CN101696388A - Fermentation cylinder with gas distributor - Google Patents
Fermentation cylinder with gas distributor Download PDFInfo
- Publication number
- CN101696388A CN101696388A CN 200910154461 CN200910154461A CN101696388A CN 101696388 A CN101696388 A CN 101696388A CN 200910154461 CN200910154461 CN 200910154461 CN 200910154461 A CN200910154461 A CN 200910154461A CN 101696388 A CN101696388 A CN 101696388A
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- China
- Prior art keywords
- gas distribution
- distribution sheet
- inlet pipe
- gas
- gaseous emission
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention relates to a fermentation cylinder, in particular to a fermentation cylinder with a gas distributor, which comprises a fermentation cylinder body, a stirrer arranged in the fermentation cylinder body, and an inlet pipe, wherein the inlet pipe comprises an inlet end and an exhaust end, the inlet end is positioned outside the fermentation cylinder body, the exhaust end extends into the fermentation cylinder body, the exhaust end of the inlet pipe and the stirrer are coaxially arranged, and the end port of the exhaust end of the inlet pipe is arranged towards the bottom of the fermentation cylinder body, the end port of the exhaust end of the inlet pipe is provided with the gas distributor, the gas distributor comprises a gas distribution sheet connected with the inlet pipe, the middle of the gas distribution sheet is provided with a connecting hole for the exhaust end of the inlet pipe to penetrate and clamp, and a plurality of vent holes are arranged in the end face of the gas distribution sheet uniformly. By adopting the technical scheme, the fermentation cylinder with the gas distributor has simple structure, good gas distribution effect and easy cleaning.
Description
Technical field
The present invention relates to a kind of fermentor tank, particularly a kind of fermentor tank with gas distributor.
Background technology
In the fermentation equipment of numerous types,, be widely used in every field such as microbiotic, amino acid, citric acid because the high oxygen consumption requirement of leavened prod mostly has ventilation concurrently and is with churned mechanically standard type fermentor tank purposes the most general again.A very important aspect of fermentor tank design is gas distributor.Good and bad growth, form, oxygen and the pipe that is directly connected to bacterial classification of gas distribution situation supported the absorption and the metabolism of thing, directly has influence on fermentation unit and productive rate thus.Though can improve the gas distribution situation by the improvement of agitator,, under many circumstances, under the operating mode of especially high ventilation ratio, the effect of depending merely on agitator is also powerless.
At present, the gas distributor that uses in the fermentor tank on market and the data is generally the single hole pipe or by the gas distribution ring of pipe coiled.The single hole tubular construction is simple, is easy to sterilization, and production process is not easy to produce the microbiological contamination problem, but has the uneven fair problem of gas distribution; Inlet pipe is extended to part coiled annular in the fermentor tank, on being wound into the side face of ring-like part, inlet pipe sets out pore then, such set-up mode gas distribution is effective, but because structure is responsible for, be easy to generate the halfway problem of sterilization, thereby cause the microbiological contamination in the production process, have influence on normally carrying out of production.
Summary of the invention
At the deficiency that prior art exists, the invention provides a kind of simple in structure, gas distribution is effective, the fermentor tank of the band gas distributor of easy cleaning.
For achieving the above object, the invention provides following technical scheme: a kind of fermentor tank with gas distributor, include the fermentation tank body, be located at intravital agitator of fermentor tank and inlet pipe, described inlet pipe includes inlet end and gaseous emission end, it is external that inlet end is in fermentor tank, the gaseous emission end extends in the fermentation tank body, the gaseous emission end of described inlet pipe extends to the lower end of agitator in the fermentation tank body, and with the coaxial setting of agitator, and the port of the gaseous emission end of inlet pipe was provided with towards the jar end of fermentation tank body, the port of the gaseous emission end of described inlet pipe is provided with gas distributor, this gas distributor includes the gas distribution sheet that is connected with inlet pipe, the middle part of this gas distribution sheet is provided with gaseous emission end for inlet pipe and penetrates and block the connecting hole of establishing, and is evenly equipped with some production wells on the end face of gas distribution sheet.
Adopt technique scheme, inlet pipe to extend to the lower end of the agitator in the fermentor tank, the gaseous emission end of inlet pipe is provided with gas distributor, and gas distributor is made of the gas distribution sheet that is connected with inlet pipe and evenly be provided with production well on it; After being provided with like this, production well directly is opened on the gas distribution sheet, without any corner and the existence at dead angle, so clean easily and sterilize, can not produce the problem of microbiological contamination; Gas distribution sheet simple in structure, convenient processing and installation, and gas can move along the end face of gas distribution sheet when gas enters in the fermentor tank by the inlet pipe place, just can on the agitator direction, move until the place, some air outlets that moves on the gas distribution sheet, improved the utilising efficiency of gas, and made that the distribution of gas is better.
The present invention further is set to: described gas distribution sheet is the plate-like setting, and the edge of the end face of gas distribution sheet at the bottom of jar is provided with the annular cover that is vertical setting with the gas distribution sheet, and the side face of this annular cover is provided with some breather holes.
Adopt technique scheme, with the setting of gas distribution sheet be plate-like mainly be since agitator to after carrying out medium in the fermentor tank and stirring, medium is the plate-like rotation, the gas distribution sheet is the distribution that helps gas after the plate-like; The setting of the annular that is connected with gas distribution sheet cover then is by in order to prevent that gas is run off by the edge of gas distribution sheet, the gas that moves to gas distribution sheet edge can move along the annular cover, discharge from the breather hole that annular puts until gas, improve gas effciency and gas distribution effect.
The present invention further is set to: described some production well combinations are arranged on the gas distribution sheet in the form of a ring, and offer the some groups of production wells of arranging in the form of a ring on the gas distribution sheet, wherein respectively organize production well and dwindle setting from outside to inside successively along gas distribution sheet radius.
Adopt the convenient on the one hand processing of arranging in the form of a ring of technique scheme, production well, then increased production well on the other hand and be positioned at fraction of coverage on the gas distribution sheet; Each organizes pore, and to dwindle setting from outside to inside successively along gas distribution sheet radius then be when moving on the gas distribution sheet for the gas that enters in the inlet pipe, prevent gas directly by the just whole discharges in the inner ring place of gas distribution sheet, thereby cause the distribution effect of gas to reduce.
The present invention further is set to: described gas distribution sheet includes upper surface and lower surface, its end face at the bottom of fermentation tank body jar is the lower surface, the other end is the upper surface, after the connecting hole at the gaseous emission end of described inlet pipe and gas distribution sheet middle part plugged together, the lower surface of the port of gaseous emission end and gas distribution sheet was in same plane.
After adopting technique scheme, the lower surface of the port of gaseous emission end and gas distribution sheet to be in same plane to guarantee that then gas is entered by inlet pipe, can move to fast on the gas distribution sheet, prevent gas loss and influence gas distribution.
Below in conjunction with accompanying drawing the present invention is further described:
Description of drawings
Fig. 1 is the structural representation of the embodiment of the invention;
Fig. 2 is the schematic perspective view of gas distributor in the embodiment of the invention;
Fig. 3 is the main diagrammatic sketch of gas distribution sheet in the embodiment of the invention;
Fig. 4 is the schematic perspective view of annular cover in the embodiment of the invention.
Embodiment
As Fig. 1, Fig. 2, Fig. 3, a kind of fermentor tank shown in Figure 4 with gas distributor, include fermentation tank body 1, be located at agitator 2 and inlet pipe 3 in the fermentation tank body 1, described inlet pipe 3 includes inlet end 31 and gaseous emission end 32, inlet end 31 is in outside the fermentation tank body 1, gaseous emission end 32 extends in the fermentation tank body 1, the gaseous emission end 32 of inlet pipe 3 extends to the lower end of agitator 2 in the fermentation tank body 1, and with agitator 2 coaxial settings, and the port of the gaseous emission end 32 of inlet pipe 3 was provided with towards the jar end 11 of fermentation tank body 1, port 321 places of the gaseous emission end 32 of inlet pipe 3 are provided with gas distributor, this gas distributor includes the gas distribution sheet 4 that is connected with inlet pipe 3, the middle part of this gas distribution sheet 4 is provided with gaseous emission end 32 for inlet pipe 3 and penetrates and block the connecting hole of establishing 41, is evenly equipped with some production wells 42 on the end face of gas distribution sheet 4.Adopt above-mentioned set-up mode, production well 42 directly is opened on the gas distribution sheet 4, without any corner and the existence at dead angle, so clean easily and sterilize, can not produce the problem of microbiological contamination; Gas distribution sheet 4 simple in structure, convenient processing and installation, and gas can move along the end face of gas distribution sheet 4 when gas enters in the fermentor tank by inlet pipe 3 places, just can on agitator 2 directions, move until 42 places, some air outlets that move on the gas distribution sheet 4, improved the utilising efficiency of gas, and made that the distribution of gas is better.
In embodiments of the present invention, gas distribution sheet 4 is the plate-like setting, need to prove that the plate-like here can be circle, also can be ellipse, certainly, be provided with gas distribution sheet 4 rectangular or trilateral also is feasible, just carry out in 2 pairs of fermentor tanks of agitator after medium stirs, medium is the plate-like rotation, gas distribution sheet 4 is the distribution that helps gas after the plate-like, thus the present invention preferred the former; Gas distribution sheet 4 edge of 11 end face at the bottom of jar is provided with the annular cover 5 that is vertical setting with gas distribution sheet 4, the side face of this annular cover 5 is provided with some breather holes 51, gas distribution sheet 4 and the 5 bonding settings of annular cover, certainly gas distribution sheet 4 also can overlap 5 by the clamping setting with annular, joining place sealing between gas distribution sheet 4 and the annular cover 5 gets final product, and breather hole 51 is rounded on the annular cover 5, certainly also can be rectangle, ellipse or trilateral, all be feasible, and circular port is easily processed; The purpose that annular cover 5 is set herein is in order to prevent that gas is run off by the edge of gas distribution sheet 4, the gas that moves to gas distribution sheet 4 edges can overlap 5 along annular and move, discharge from the breather hole 51 on the annular cover 5 until gas, improve gas effciency and gas distribution effect.
In embodiments of the present invention, some production well 42 combinations are arranged on the gas distribution sheet 4 in the form of a ring, and offer the some groups of production wells of arranging in the form of a ring 42 on the gas distribution sheet 4, wherein respectively organize production well 42 and dwindle setting from outside to inside successively along the radius of gas distribution sheet 4; Being provided with like this is when moving on the gas distribution sheet 4 for the gas that enters in inlet pipe 3, prevents gas directly by the just whole discharges in the inner ring place of gas distribution sheet 4, thereby causes the distribution effect of gas to reduce.Gas distribution sheet 4 includes upper surface 43 and lower surface 44, its end face of 11 at the bottom of 1 jar of tank body of fermentation is lower surface 44, the other end is upper surface 43, after the gaseous emission end 32 of described inlet pipe 3 plugged together with the connecting hole 41 at gas distribution sheet 4 middle parts, the port 321 of gaseous emission end 32 was in same plane with the lower surface 44 of gas distribution sheet 4.After the port 321 of gaseous emission end 32 and the lower surface 44 of gas distribution sheet 4 are in same plane and can guarantee that then gas is entered by inlet pipe 3, can move to fast on the gas distribution sheet 4, prevent gas loss and influence gas distribution.Certainly, to extend out also be feasible to the port 321 of gaseous emission end 32.
Claims (6)
1. fermentor tank with gas distributor, include the fermentation tank body, be located at intravital agitator of fermentor tank and inlet pipe, described inlet pipe includes inlet end and gaseous emission end, it is external that inlet end is in fermentor tank, the gaseous emission end extends in the fermentation tank body, it is characterized in that: the gaseous emission end of described inlet pipe extends to the lower end of agitator in the fermentation tank body, and with the coaxial setting of agitator, and the port of the gaseous emission end of inlet pipe was provided with towards the jar end of fermentation tank body, the port of the gaseous emission end of described inlet pipe is provided with gas distributor, this gas distributor includes the gas distribution sheet that is connected with inlet pipe, the middle part of this gas distribution sheet is provided with gaseous emission end for inlet pipe and penetrates and block the connecting hole of establishing, and is evenly equipped with some production wells on the end face of gas distribution sheet.
2. the fermentor tank of band gas distributor according to claim 1, it is characterized in that: described gas distribution sheet is the plate-like setting, the edge of the end face of gas distribution sheet at the bottom of jar is provided with the annular cover that is vertical setting with the gas distribution sheet, and the side face of this annular cover is provided with some breather holes.
3. the fermentor tank of band gas distributor according to claim 2 is characterized in that: described gas distribution sheet is provided with the welding of annular cover.
4. the fermentor tank of band gas distributor according to claim 1 and 2, it is characterized in that: described some production well combinations are arranged on the gas distribution sheet in the form of a ring, and offer the some groups of production wells of arranging in the form of a ring on the gas distribution sheet, wherein respectively organize production well and dwindle setting from outside to inside successively along the radius of gas distribution sheet.
5. according to the fermentor tank of claim 1 or 2 or 3 described band gas distributors, it is characterized in that: described gas distribution sheet includes upper surface and lower surface, its end face at the bottom of fermentation tank body jar is the lower surface, the other end is the upper surface, after the connecting hole at the gaseous emission end of described inlet pipe and gas distribution sheet middle part plugged together, the lower surface of the port of gaseous emission end and gas distribution sheet was in same plane.
6. the fermentor tank of band gas distributor according to claim 4, it is characterized in that: described gas distribution sheet includes upper surface and lower end, its end face at the bottom of fermentation tank body jar is the lower surface, the other end is the upper surface, after the connecting hole at the gaseous emission end of described inlet pipe and gas distribution sheet middle part plugged together, the lower surface of the port of gaseous emission end and gas distribution sheet was in same plane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200910154461 CN101696388A (en) | 2009-10-29 | 2009-10-29 | Fermentation cylinder with gas distributor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200910154461 CN101696388A (en) | 2009-10-29 | 2009-10-29 | Fermentation cylinder with gas distributor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101696388A true CN101696388A (en) | 2010-04-21 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200910154461 Pending CN101696388A (en) | 2009-10-29 | 2009-10-29 | Fermentation cylinder with gas distributor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101696388A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101870946A (en) * | 2010-06-08 | 2010-10-27 | 南京工业大学 | Bioreactor suitable for fermentation of long-chain polyunsaturated fatty acid |
| CN102408985A (en) * | 2011-10-28 | 2012-04-11 | 河南农业大学 | Equipment for producing ethanol by fermentation of biomass synthesis gas |
| CN102500286A (en) * | 2010-10-26 | 2012-06-20 | 周洪山 | Gas distributor |
| CN103756889A (en) * | 2013-12-31 | 2014-04-30 | 江苏元洲生物工程有限公司 | High-efficiency gas distributor |
| CN103952293A (en) * | 2014-05-04 | 2014-07-30 | 梁山菱花生物科技有限公司 | Air distributor of fermentation tank utilizing ultrasonic waves for defoaming |
| CN106635740A (en) * | 2011-09-30 | 2017-05-10 | 生命科技股份有限公司 | Container with film sparger |
| CN107177502A (en) * | 2017-07-18 | 2017-09-19 | 汇森生物设备镇江有限公司 | A kind of high performance plant cell fermentation tank |
| CN108300649A (en) * | 2018-04-08 | 2018-07-20 | 浙江长城搅拌设备股份有限公司 | Stirring reactor in process of high-density fermentation |
| US10123940B2 (en) | 2014-06-26 | 2018-11-13 | Advanced Scientific, Inc. | Bag assembly and system for use with a fluid |
| US10301585B2 (en) | 2011-09-29 | 2019-05-28 | Life Technologies Corporation | Filter systems for separating microcarriers from cell culture solutions |
| US10328404B2 (en) | 2005-04-22 | 2019-06-25 | Life Technologies Corporation | Gas spargers and related container systems |
| US10589197B2 (en) | 2016-12-01 | 2020-03-17 | Life Technologies Corporation | Microcarrier filter bag assemblies and methods of use |
-
2009
- 2009-10-29 CN CN 200910154461 patent/CN101696388A/en active Pending
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10328404B2 (en) | 2005-04-22 | 2019-06-25 | Life Technologies Corporation | Gas spargers and related container systems |
| CN101870946A (en) * | 2010-06-08 | 2010-10-27 | 南京工业大学 | Bioreactor suitable for fermentation of long-chain polyunsaturated fatty acid |
| CN102500286B (en) * | 2010-10-26 | 2014-06-04 | 周洪山 | Gas distributor |
| CN102500286A (en) * | 2010-10-26 | 2012-06-20 | 周洪山 | Gas distributor |
| US10934514B2 (en) | 2011-09-29 | 2021-03-02 | Life Technologies Corporation | Filter systems for separating microcarriers from cell culture solutions |
| US11840684B2 (en) | 2011-09-29 | 2023-12-12 | Life Technologies Corporation | Filter systems for separating microcarriers from cell culture solutions |
| US10301585B2 (en) | 2011-09-29 | 2019-05-28 | Life Technologies Corporation | Filter systems for separating microcarriers from cell culture solutions |
| CN106635740A (en) * | 2011-09-30 | 2017-05-10 | 生命科技股份有限公司 | Container with film sparger |
| US10843141B2 (en) | 2011-09-30 | 2020-11-24 | Life Technologies Corporation | Container with film sparger |
| US10350554B2 (en) | 2011-09-30 | 2019-07-16 | Life Technologies Corporation | Container with film Sparger |
| CN106635740B (en) * | 2011-09-30 | 2019-03-15 | 生命科技股份有限公司 | Container with film sprinkler |
| CN102408985A (en) * | 2011-10-28 | 2012-04-11 | 河南农业大学 | Equipment for producing ethanol by fermentation of biomass synthesis gas |
| CN103756889A (en) * | 2013-12-31 | 2014-04-30 | 江苏元洲生物工程有限公司 | High-efficiency gas distributor |
| CN103756889B (en) * | 2013-12-31 | 2015-10-21 | 江苏元洲生物工程有限公司 | Efficient gas sparger |
| CN103952293A (en) * | 2014-05-04 | 2014-07-30 | 梁山菱花生物科技有限公司 | Air distributor of fermentation tank utilizing ultrasonic waves for defoaming |
| CN103952293B (en) * | 2014-05-04 | 2015-07-08 | 梁山菱花生物科技有限公司 | Air distributor of fermentation tank utilizing ultrasonic waves for defoaming |
| US10123940B2 (en) | 2014-06-26 | 2018-11-13 | Advanced Scientific, Inc. | Bag assembly and system for use with a fluid |
| US10463571B2 (en) | 2014-06-26 | 2019-11-05 | Advanced Scientifics, Inc. | Bag assembly and bag system for use with a fluid |
| US10589197B2 (en) | 2016-12-01 | 2020-03-17 | Life Technologies Corporation | Microcarrier filter bag assemblies and methods of use |
| US11344827B2 (en) | 2016-12-01 | 2022-05-31 | Life Technologies Corporation | Microcarrier filter bag assemblies and methods of use |
| US11890557B2 (en) | 2016-12-01 | 2024-02-06 | Life Technologies Corporation | Microcarrier filter bag assemblies and methods of use |
| CN107177502A (en) * | 2017-07-18 | 2017-09-19 | 汇森生物设备镇江有限公司 | A kind of high performance plant cell fermentation tank |
| CN108300649A (en) * | 2018-04-08 | 2018-07-20 | 浙江长城搅拌设备股份有限公司 | Stirring reactor in process of high-density fermentation |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20100421 |