CN101690753A - Chinese medicament preparation for treating burn injuries and preparation method thereof - Google Patents
Chinese medicament preparation for treating burn injuries and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicament preparation for treating burn injuries and a preparation method thereof. Based on the tests and researches performed by the inventor in a long period, the medicament with excellent treatment effect is prepared form the following raw materials in dosage by mass: 500 to 1,050 grams of giant knotweed rhizome, 125 to 255 grams of garden burnet root, 125 to 255 grams of Chinese ilex leaf, 125 to 255 grams of scandent schefflera stem and leaf, 80 to 170 grams of dahurian angelica root, and 60 to 130 grams of liquorice root. In the Chinese medicament preparation, the giant knotweed rhizome, the garden burnet root, the Chinese ilex leaf, the scandent schefflera stem and leaf, the dahurian angelica root and the liquorice root are selected for combination that allows all the raw material medicaments to generate a synergy effect in efficacy to effectively dissipate heat and remove toxins, eliminate dampness, eliminate swelling and stop pain, relieve itching and protect the skin and promote tissue regeneration; and compared with the prior art, the Chinese medicament preparation has the advantages of no side effect, low treating cost, quick pain alleviation, quick control of exudation, highly efficient infectious resistance and quick healing and can treat burn injuries more effectively, so that the Chinese medicament preparation is worthy of clinical popularization and application.
Description
Affiliated technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of extreme misery for the treatment of and scald Chinese medicine preparation of burn and preparation method thereof.
Background technology
The damage of a kind of skin that factor caused such as burn is meant the electric flame of various thermals source (hydrothermal solution, flame, vapours and thermometal etc.), burns, electric burn, lonizing radiation, chemical attack even dark tissue, wherein heat injury is the most common.Ancient literature such as the Tang Dynasty " very heavy side " (652), Ming Dynasty's " Waike Zhengzong, Orthodox Manual of External Diseases " (1671), the Qing Dynasty " surgery great achievement " (1665) etc. thinks that all burn is a pyretic toxicity. TCM Document thinks that burn is the injury of boiling water raging fire now, intenseness of heat is then rotten, skin rots, and muscle muscle arteries and veins is immersed in contamination, so that the skin and flesh damage, stay scar to disable, very then threat to life.Ancient Chinese medicine doctor heat clearing away, detoxifcation, poison holding be with for oral administration, and removing toxic substances and promoting granulation is with external treatment, cures and save countless fire victims.Behind right patient's burn, all persons who uses the ice of cold water ice cube cold, to force the pathogenic heat stasis of blood to advance again subcutaneous in addition, and cold and heat are fought mutually, damage is to dark, the external-applied ointment polyphyly is refrigerant now in addition, wraps not only but also wrap up in, and it is rotten difficult to go bad, stay scar person crowd, moreover also there is following shortcoming: 1, wrapping burn surface, the smearing ointment amount is big, waste medical material and medical material; 2, ointment is many by vegetable oil, vaseline modulation, makes not easy cleaning of wound surface; 3, unhygienic, easy suppuration, easily pollution resistant bed is by clothes; 4, flushing is changed dressings and is damaged the skin island repeatedly, prolongs the epithelization time, early stage complete the healing of influence; 5, a shallow II ° infection becomes dark II ° or III ° and burns and stay cicatrix, very then influences function; 6, the medical expense costliness increases the weight of the patient burden.
Summary of the invention
So still there is demand in the Chinese medicine preparation that the mankind better treat burn to curative effect, up to now, also do not find the report of any relevant medicine of the present invention, for solving the problem that the external-use burn medicine exists at present, the inventor through for a long time, repeatedly research, constantly research improves the clinical efficacy that improves treatment burn medicine, has found the Chinese medicine preparation of the treatment burn of better efficacy finally, has finished the present invention.The object of the invention provides a kind of controlling aches soon, and control is oozed out fast, forms a scab soon, and infection is efficient, and it is fast to fully recover, and can more effectively treat the Chinese medicine preparation of burn.
Another object of the present invention provides a kind of preparation method of this Chinese medicine preparation.
The consumption that medicine of the present invention is formed part is that inventor's process gropes to sum up to get for a long time in a large number, and the each component consumption all has curative effect preferably in following weight compatibility ratio range:
Rhizoma Polygoni Cuspidati 500-1050 gram, Radix Sanguisorbae 125-255 gram, Folium Ilicis Purpureae 125-255 gram, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 125-255 gram, Radix Angelicae Dahuricae 80-170 gram, Radix Glycyrrhizae 60-130 gram.
For reaching above-mentioned purpose, the preparation method that the present invention takes is: take by weighing the various Chinese medicines of above-mentioned weight compatibility proportioning, put into aluminum pot, add pure water, addition is as the criterion to cover medicine, boils 30-60 minute, filters, and gets medicinal liquid; Add pure water in the medicine after above-mentioned filtration, addition is as the criterion to cover medicine, boils 30-60 minute, filters, and gets medicinal liquid; Twice medicinal liquid mixed, be concentrated into concentration and be the concentrated medicament more than 30%, and then this concentrated medicament is divided in 10 milliliters, 20 milliliters, 50 milliliters, 100 milliliters, 250 milliliters the vial, above-mentioned vial and bottle stopper are put into food steamer to be steamed and boiled 50-70 minute, the medicinal liquid of packing behind the high temperature sterilization is covered bottle stopper, and the wax medicated cap seals standby.
Medicament selection Rhizoma Polygoni Cuspidati of the present invention, Radix Sanguisorbae, Folium Ilicis Purpureae, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), the Radix Angelicae Dahuricae, Radix Glycyrrhizae make up, and make each efficacy of drugs produce synergism these drug regimens, thereby the detoxifcation of dispelling the heat effectively, dampness, detumescence relieve the pain, antipruritic, skin protection granulation promoting; First-selected Rhizoma Polygoni Cuspidati among the present invention, its property is bitter flat, " property of medicine opinion " day: Rhizoma Polygoni Cuspidati is sweet flat, expelling wind and removing dampness, the removing blood stasis with potent drugs latus rectum is controlled wind.Wet bones and muscles pain, jaundice due to damp-heat, the stranguria with turbid discharge leukorrhagia, women's amenorrhea, lochiostasis is scalded." property of medicine opinion " claims this product to press all pyretic toxicity, " Bai Huazi book on Chinese herbal medicine " meaning this product evacuation of pus master furuncle carbuncle poison." your continent side's medicine among the people collection " claims this product convergence of drying, expelling pathogenic factors from the exterior dissipating blood stasis, external treatment burn.This product is cool and cold, and both relieved inflammation or internal heat poison and do not check steam and loose, Fa Gan and moistening, the capable urine of promoting diuresis and pus discharge, oral administration and externally is executed it in a large number, and is useful and harmless.Facts have proved and clinically utilize Rhizoma Polygoni Cuspidati to act on burn wound to make secretions and ooze out obvious minimizing, painless stimulation, the incrustation decrustation is fast, is monarch drug; The harness the river key medicine of burning hot wound of Radix Sanguisorbae, Folium Ilicis Purpureae, assist monarch drug dispel the heat more fully detoxifcation, dampness, subside a swelling, relieve the pain, antipruritic, so be ministerial drug.Radix Sanguisorbae acid is cold nontoxic, cooling blood for hemostasis, and heat-clearing and toxic substances removing is controlled the burn key medicine, has obvious antipruritic convergence, an effect of the granulation that disappears.Folium Ilicis Purpureae has broad-spectrum antibacterial action, the kind scald ulcer of controlling, disunion for a long time.Treat various infection oral administration and externallies, do not see hepatorenal damage.The assistant Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), the Radix Angelicae Dahuricae is got the effect of relieving the pain of its promoting blood circulation to remove obstruction in the collateral, burn wound's pain time is shortened or disappearance, thereby strengthens the effect of relieving the pain of this product.And the hot temperature of the Radix Angelicae Dahuricae is nontoxic, dispeiling pathogenic wind and removing dampness, subduing swelling and detoxicating, controls that the headache superciliary ridge is painful, toothache nasal sinusitis cold-damp stomachache hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge ulcer sores, skin pruritus." herbal classic " meaning longue skin is moist.The broken stagnated blood of " Japan hanako materia medica " meaning Radix Angelicae Dahuricae and tissue regeneration promoting blood is controlled carbuncle carbuncle on the back, scrofula hemorrhoidal hamorrhage anal fistula, the evacuation of pus granulation promoting is gone face infantile malnutrition defect abdominal mass.The messenger drug Radix Glycyrrhizae, sweet in the mouth is flat, goes into taste lung meridian and middle emergency, lung moistening detoxifcation coordinating the actions of various ingredients in a prescription; " book on Chinese herbal medicine is just " day: the Radix Glycyrrhizae flavor is main sweet, and the property that must neutralize has the merit of transferring benefits, so its poison that looses that poison gets, firm medicine gets its property of sum, and what medicine administered to bring out the cold got helps outside it, put in poison delay its speed, go into gas with the gas medicine, go into blood with the blood medicine.The promoting blood circulation so moisten skin.
Drug matching preparation color and luster of the present invention is bright reddish brown not muddy, abnormal smells from the patient delicate fragrance.The external-use burn wound surface, heat-clearing and toxic substances removing and cold is evacuated diathermanously and not dry, supports the profit skin and oiliness, and wound surface is dry and comfortable and do not ache.
Medicine treatment burn of the present invention, the main atomizing wet exposing therapy that adopts, be primarily aimed at large-area burns of shallow II ° of degree and dark II °＜50% burn, to the fire victim that goes to a doctor at first debridement burn wound then this product atomizing shape ground is sprayed on the position of burning, pain relief after ten minutes.Large-area burns 40-60 minute, pain promptly disappeared.Little person need not handle to blister, and blister the greater goes out with the sterile needle bank of tubes, the skin avulsion, this product is directly sprayed disperse in wound surface, be no more than twenty four hours and promptly form a scab.Fire victim to wound surface suppurative infection directly washes wound surface with this product, the tissue of the putrid necrosis of debridement and pus, and the wound surface pus disappeared and formed a scab next day.To electric fire burn, need not excise eschar, this product is directly sparged the burn position, treat white row decrustation after its epithelization, more the no scar in back.All oral mucosas, throat, nostril, eyelid, sclera, burn are burnt, external auditory meatus is burnt, and all available this product is directly sprayed, and is without any side effects.Just spray once, after one hour, every one hour with this product disperse in suitable per ten minutes, the disperse spraying once, control the painful time by shortening to a few minutes to 1 hour in original 3 hours until recovery from illness, until the no longer pain of fully recovering, ooze out by 72 hours and be reduced to 24-30 hour.Burn position skin avulsion, i.e. incrustation in 12 hours.The sterilization anti-infection ability obviously improves, and clinical practice proves that this medicine, all has and suppresses and killing action as escherichia coli, staphylococcus aureus, bacillus pyocyaneus etc. various suppuration bacterium.To burnt many days and through the treatment the patient, reuse medicine flushing of the present invention spraying, pus disappeared or obviously minimizing in second day, can substitute the general disinfectant solution that washes burn wound fully with this product, and there is not the side effect of pain and injured skin, and very fast incrustation, treat decrustation voluntarily after its epithelization, the cicatrix rate of dark II ° and lII ° of burn is reduced to floor level.Compared with prior art, the present invention have medical expense low, control painfully fast, control is oozed out fast, incrustation is fast, infection is efficient, it is fast fully recover, can more effectively treat the advantage of burn, worth clinical application.
Adopt Chinese medicine of the present invention to control the burn preparation and directly sparge the burn position, clinical effectiveness shows the following aspects: 1, the burn time sparged the burn position continuously with this product in 15-30 minute, pain relieving rapidly, skin returns to the normal colour of skin gradually by flushing, promptly take off the shallow cutin skin of one deck about one week,, directly sparge burn site the fire victim of blister and skin avulsion is arranged, very fast natural drying need not be wrapped up.2, the medicinal cost of raw material of this product is low, and existing good economic benefit can alleviate patient's financial burden again.3, save medicinal materials, convenient and healthy, do not pollute clothing, be convenient to traumatic condition and observe and nurse.4, manufacturing process is easy to grasp, and clinical effectiveness and economic benefit are very considerable.5, this product is the good medicine of tourism indispensability at home, and water, fire burn are scalded, spraying immediately, and pain relieving is not rapidly got blister.Sparge the burn position repeatedly, promptly healed the same day.6, this product has been widened the burn treating field, and oral cavity, nostril, throat, eyelid, external auditory meatus and privileged sites are all had tangible curative effect.
The specific embodiment
The present invention is made by following weight compatibility proportion raw material medicine: Rhizoma Polygoni Cuspidati 500-1050 gram, Radix Sanguisorbae 125-255 gram, Folium Ilicis Purpureae 125-255 gram, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 125-255 gram, Radix Angelicae Dahuricae 80-170 gram, Radix Glycyrrhizae 60-130 gram.
The preparation method that the present invention takes is: take by weighing the various Chinese medicines of above-mentioned weight compatibility proportioning, put into aluminum pot, add pure water, addition is as the criterion to cover medicine, boils 30-60 minute, filters, and gets medicinal liquid; Add pure water in the medicine after above-mentioned filtration, addition is as the criterion to cover medicine, boils 30-60 minute, filters, and gets medicinal liquid; Twice medicinal liquid mixed, be concentrated into concentration and be the concentrated medicament more than 30%, and then this concentrated medicament is divided in 10 milliliters, 20 milliliters, 50 milliliters, 100 milliliters, 250 milliliters the vial, above-mentioned vial and bottle stopper are put into food steamer to be steamed and boiled 50-70 minute, the medicinal liquid of packing behind the high temperature sterilization is covered bottle stopper, and the wax medicated cap seals standby.
Embodiment 1:
The present invention is made by following weight compatibility proportion raw material medicine: Rhizoma Polygoni Cuspidati 500 grams, Radix Sanguisorbae 125 grams, Folium Ilicis Purpureae 125 grams, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 125 grams, the Radix Angelicae Dahuricae 80 grams, Radix Glycyrrhizae 60 grams.
Embodiment 2:
The present invention is made by following weight compatibility proportion raw material medicine: Rhizoma Polygoni Cuspidati 700 grams, Radix Sanguisorbae 200 grams, Folium Ilicis Purpureae 200 grams, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 200 grams, the Radix Angelicae Dahuricae 100 grams, Radix Glycyrrhizae 100 grams.
Embodiment 3:
The present invention is made by following weight compatibility proportion raw material medicine: Rhizoma Polygoni Cuspidati 1050 grams, Radix Sanguisorbae 255 grams, Folium Ilicis Purpureae 255 grams, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 255 grams, the Radix Angelicae Dahuricae 170 grams, Radix Glycyrrhizae 130 grams.
Chinese medicine preparation of the present invention is through repeated screening checking, nontoxic, pure Chinese medicine.The present invention adds the burn external atomizing spray that pure water extracts through decocting and concentrating.In preparation process, note sterilization.When facing the disease use, this concentrated medicament is poured into respectively in 10 milliliters, 20 milliliters, 50 milliliters, 100 milliliters, the 250 milliliters sterile watering cans, directly sparged the burn position.
Character: the liquid thing of pale brown color, flavor fragrance, slightly pained acid, volatilization slightly.
Pharmacology: facts have proved all has inhibition and killing action to staphylococcus aureus, escherichia coli, bacillus pyocyaneus etc., and the painful effect in good town is arranged, and there is convergence in burn wound, controls the effect of oozing out, protecting from infection and promoting epithelization.
Function cures mainly: heat radiation detoxifcation, dampness, detumescence relieve the pain, antipruritic, skin protection granulation promoting.Treat various thermals source and chemical substance extremely skin surface redness, painful, the vesicle of burning, I ° of burn of skin exfoliation, shallow II ° burn, dark II ° burn and area 5% with interior III ° burn.
Usage: adopt directly to sparge the burn position,, shake up use if any precipitation; Do not affect the treatment.The spraying of per 10 minutes of burn initial stage is once per hour sprayed once later on, and wound surface exposes need not wrapped up.
Points for attention: 1, the major burn patients that area is bigger or other serious diseases are arranged, symptomatic treatment should use under physician guidance or be in hospital.2, should lie up at lower limb in the burn position.3, fasting beef, the flesh of fish, wine and the hot thing of pungent Rhizoma Zingiberis Recens Bulbus Allii.
50 milliliters/bottle of specifications, 100 milliliters/bottle, 250 milliliters/bottle.
Medicinal liquid effect duration: 2 years
Product of the present invention uses through 1200 many cases patients, and effective percentage is up to more than 98%.
Model case:
Case 1, Wang, man, 22 years old, the Fangcheng County, Henan Province Si Lidian township village electrician that sticks together, on January 20th, 2004 is because of transformator combustion fire, women's head-ornaments, neck, trunk, the fire burn of extremity electricity, wherein hair burns, both hands skin Jiao take off, and area reaches more than 50%, and dark II ° reaches more than 15%, in township's hospitalize after 48 hours, because of severe infections, 41 ℃ of hyperpyrexias infect, control and ooze out through control, especially after using product of the present invention, ooze out and infect and contained, the wound surface drying, pus reduces, treat incrustation in 13 days, took off frame in 17 days, no scar is seamless, and the whole family is very grateful.
Case 2: Cui, the woman, 18 years old, the worker of oil company, Fangcheng County was scalded whole body by boiled water, and area accounts for 45%, and the degree of depth reaches dark II °, behind the combination therapy of Chinese and western of system, behind the external product of the present invention, thoroughly recovery from illness in 16 days, nothing stays any cicatrix.
Case 3: first will Pu, man, 49 years old, Gu Zhuan Dian Miaogang people from village, Fangcheng County, 95 years native small arms propellant burn faces, cervical region, shirtfront and bilateral upper limb, area accounts for 38%, and the shallow II of depth of burn part °, most of dark II °, behind the external product of the present invention, treat incrustation in 12 days and come off, no scar is seamless.
Case 4: Zhang Chundang, the man, 18 years old, refreshing woods peach garden Gou Yangwan people from village in four li shops, Fangcheng County, the mechanic of Fangcheng County vehicle repairing factory, fire burn because of gasoline accidentally on June 5th, 1997, the bilateral upper limb, cervical region, facial, shirtfront and burn of lower limb, wherein, the right side, the burn of upper limb area accounts for 17%, face, burn of neck region accounts for 5%, and breast and burn of trunk area account for 16%, bilateral burn of lower limb right side accounts for 12%, the left side burn surface area accounts for 3%, and wherein the dark II of burn of upper limb ° accounts for 15%, neck, breast, the dark II of a trunk ° burn accounts for 8%, the dark II of a right side lower limb ° burn surface area accounts for 6%, hand III ° of burn to the carpal joint in right side accounts for 1.5%, and TBS accounts for 53%, use product of the present invention after, control in the 2nd day is oozed out, suppurative infection does not appear during the treatment, incrustation in the 3rd day, beginning decrustation in the 8th day, except that right hand hand has the white abnormal pigmentary deposit on the skin of strip, recovery from illness in 12 days.
Claims (2)
1. Chinese medicine preparation for the treatment of burn is characterized in that it is made by following weight compatibility proportion raw material medicine: Rhizoma Polygoni Cuspidati 500-1050 gram, Radix Sanguisorbae 125-255 gram, Folium Ilicis Purpureae 125-255 gram, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 125-255 gram, Radix Angelicae Dahuricae 80-170 gram, Radix Glycyrrhizae 60-130 gram.
2. a preparation method for the treatment of the Chinese medicine preparation of burn according to claim 1 is characterized in that this preparation method is: take by weighing the various Chinese medicines of above-mentioned weight compatibility proportioning, put into aluminum pot, add pure water, addition is as the criterion to cover medicine, boils 30-60 minute, filter, get medicinal liquid; Add pure water in the medicine after above-mentioned filtration, addition is as the criterion to cover medicine, boils 30-60 minute, filters, and gets medicinal liquid; Twice medicinal liquid mixed, be concentrated into concentration and be the concentrated medicament more than 30%, and then this concentrated medicament is divided in 10 milliliters, 20 milliliters, 50 milliliters, 100 milliliters, 250 milliliters the vial, above-mentioned vial and bottle stopper are put into food steamer to be steamed and boiled 50-70 minute, the medicinal liquid of packing behind the high temperature sterilization is covered bottle stopper, and the wax medicated cap seals standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101724048A CN101690753B (en) | 2009-09-28 | 2009-09-28 | Chinese medicament preparation for treating burn injuries and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101724048A CN101690753B (en) | 2009-09-28 | 2009-09-28 | Chinese medicament preparation for treating burn injuries and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101690753A true CN101690753A (en) | 2010-04-07 |
| CN101690753B CN101690753B (en) | 2011-06-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2009101724048A Expired - Fee Related CN101690753B (en) | 2009-09-28 | 2009-09-28 | Chinese medicament preparation for treating burn injuries and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247444A (en) * | 2011-08-18 | 2011-11-23 | 胡勋禄 | Medicine for treating burn and scald and preparation method thereof |
| CN103893319A (en) * | 2014-04-09 | 2014-07-02 | 四川金堂海纳生物医药技术研究所 | Pain-relieving ointment for treating mild and deep second degree burns and scalds and preparation method of pain-relieving ointment |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1159334A (en) * | 1996-03-13 | 1997-09-17 | 冉德学 | Quick healing ointment for scald |
| CN1180805C (en) * | 2001-10-16 | 2004-12-22 | 章国华 | Medicine for curing burn and scald and its production method |
| CN1931265A (en) * | 2005-09-16 | 2007-03-21 | 贵州环宇药业有限公司 | Externally applied Chinese medicine spray for treating burns and scalds |
| CN100457155C (en) * | 2006-06-22 | 2009-02-04 | 贾付成 | Medicine for treating burn and scald |
-
2009
- 2009-09-28 CN CN2009101724048A patent/CN101690753B/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247444A (en) * | 2011-08-18 | 2011-11-23 | 胡勋禄 | Medicine for treating burn and scald and preparation method thereof |
| CN102247444B (en) * | 2011-08-18 | 2013-01-16 | 胡勋禄 | Medicine for treating burn and scald and preparation method thereof |
| CN103893319A (en) * | 2014-04-09 | 2014-07-02 | 四川金堂海纳生物医药技术研究所 | Pain-relieving ointment for treating mild and deep second degree burns and scalds and preparation method of pain-relieving ointment |
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| CN101690753B (en) | 2011-06-08 |
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Inventor after: Song Changsheng Inventor after: Song Jinlu Inventor after: Lv Jianli Inventor after: Zhou Rui Inventor after: Sun Taian Inventor after: Wang Xinjun Inventor before: Song Changsheng Inventor before: Song Jinlu Inventor before: Zhou Rui Inventor before: Sun Taian Inventor before: Wang Xinjun |
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Free format text: CORRECT: INVENTOR; FROM: SONG ZHANGSHENG SONG JINLU ZHOU RUI SUN TAIAN WANG XINJUN TO: SONG ZHANGSHENG SONG JINLU LV JIANLI ZHOU RUI SUN TAIAN WANG XINJUN |
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Granted publication date: 20110608 Termination date: 20130928 |