CN101637623A - Dental tampon and preparation method thereof - Google Patents
Dental tampon and preparation method thereof Download PDFInfo
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- CN101637623A CN101637623A CN200910041914A CN200910041914A CN101637623A CN 101637623 A CN101637623 A CN 101637623A CN 200910041914 A CN200910041914 A CN 200910041914A CN 200910041914 A CN200910041914 A CN 200910041914A CN 101637623 A CN101637623 A CN 101637623A
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Abstract
The invention provides a dental tampon which contains fibrous protein and polysaccharides, wherein the fibrous protein contains collagen, and the collagen accounts for 10-90% of the total mass of thedental tampon according to mass percent; and the dental tampon can also contain organic polymeric materials, and the organic polymeric materials account for 20-0.05% of the total mass of the dental tampon according to mass percent. The invention further provides a preparation method of the dental tampon, comprising the steps of stirring and mixing raw materials of the dental tampon, and then sizing and freeze-drying the raw materials in a mold to obtain the integrally formed dental tampon. The dental tampon mainly uses the collagen for stopping bleeding, has the shape conforming to tooth structure characteristics of all age groups, is a disposable sterile non-toxic dental haemostatic material, has convenient use and simple operation, and can stop bleeding for the gingival wound surface caused by tooth extraction.
Description
Technical field
The present invention relates to dental care articles for use field, be specifically related to a kind of dentistry tampon and preparation method thereof.
Background technology
Present clinical odontopathy patient's number increases, and the patient relates to child, youth, mid-aged population.Wherein juvenile's dental caries sickness rate is up to more than 90%, and old dental caries prevalence reaches 98.4%.Clinical thorough treatment odontopathy adopts the mode of exodontia dental filling more.But can be hemorrhage in the exodontia process because of the gingiva wound surface.Conventional hemostasis method is doctor's on-the-spot self-control cotton balls or gauze ball hemostasis by compression, generally requires the patient to sting the cotton balls or the gauze ball of hemostasis by compression after exodontia, and the patient can spue after 30 minutes to 1 hour.Hemostasis by compression can be oppressed the open blood vessel of tooth extraction wound, makes blood form the thrombosis artery-clogging and hemostasis automatically at the broken ends of fractured bone, this process generally at least 30 minutes, and cotton balls or the gauze ball of removing compressing too early do not reach the hemostasis purpose.Brush teeth after gargling for a long time in the exodontia back, the blood clot of wound surface is easy to come off, and makes inaccessible blood vessel open, hemorrhage once again again.
The doctor utilizes the method for on-the-spot self-control cotton balls or gauze ball hemostasis by compression that following shortcoming is arranged: 1. it is longer to reach thorough hemostasis required time, and needs the sufferer close fit; 2. cotton yarn needs clinician's field fabrication to become to meet the specification of sufferer demand, and more time-consuming, the patient often needs the long period to wait for; 3. cotton yarn hemostatic material non-once sex hygiene articles for use do not have security guarantee to the patient; 4. cotton yarn can carry out hemostasis by compression to the gingiva wound surface less petechia, back of having tooth pulled out, but to the patient of big wound surface anthemorrhagic difficulty, must be in conjunction with local styptic powder and the hemorrhage of using, or wound surface sewed up the hemostasis processing; 5. the cotton yarn hemostasis only is a physics hemostasis method, can not play the healing effect to wound surface.Therefore general exodontia patient often need after the exodontia through 1 week about in addition diet, the life of longer time adjust, could effectively promote the growth of wound healing and newborn gingiva tissue.
Summary of the invention
For overcoming above-mentioned technological deficiency, one of purpose of the present invention provides a kind of dentistry tampon, and this dentistry tampon carries out drug hemostasis, more effective convenience of stopping blooding after having tooth pulled out.
For achieving the above object, adopt following technical scheme:
A kind of dentistry tampon of the present invention, comprise fibrous protein and polysaccharide, described fibrous protein comprises collagen, described collagen is the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, the mass percent that described collagen accounts for described dentistry tampon gross mass is 10%-90%, and all the other compositions complement to 100%.The character of described collagen comprises sponge, powder or liquid preparation.
Further, described dentistry tampon also comprises high-molecular organic material, wherein, the mass percent that described high-molecular organic material accounts for described dentistry tampon gross mass is 20%-0.05%, the mass percent that collagen accounts for described dentistry tampon gross mass is 10%-90%, and all the other compositions complement to 100%.
Preferably, described fibrous protein comprises collagen, fibrin or gelatin.
Preferably, described polysaccharide comprises chitosan, hyaluronic acid and sodium salt thereof, alginic acid and sodium salt thereof.
Preferably, described high-molecular organic material comprises cellulose, polyvinyl alcohol, polyvinylpyrrolidone or politef.
Preferably, the shape of described tampon cooperates with the gingiva nest.
Preferred, described tampon be shaped as cone.
Preferably, described tampon is one-body molded.
Preferably, the thickness of described tampon is 0.2～0.6cm, highly is 0.5～1.6cm, and width is 0.2～1.5cm.
At child, teenager, can use the dentistry tampon of junior size, the junior size of this dentistry tampon is thickness 0.2～0.6cm, height 0.5～1.0cm, width 0.2～0.8cm.At the young and the middle aged, can use the dentistry tampon of medium size, the medium size of this dentistry tampon is thickness 0.3～0.6cm, height 0.5～1.5cm, width 0.4～1.2cm; At elderly population, can use the dentistry tampon of queen size, the queen size of this dentistry tampon is thickness 0.4～0.6cm, height 0.5～1.6cm, width 0.5～1.5cm.
Second purpose of the present invention provides a kind of preparation method of dentistry tampon, and after the raw material stirring of dentistry tampon was mixed, typing and carry out lyophilization in mould obtained integrated dentistry tampon.
The raw material packet fibrousness albumen and the polysaccharide of above-mentioned dentistry tampon, described fibrous protein comprises collagen, described collagen is the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, the mass percent that described collagen accounts for described dentistry tampon gross mass is 10%-90%, and all the other compositions complement to 100%.
Further, the raw material of above-mentioned dentistry tampon also comprises high-molecular organic material, wherein, the mass percent that described high-molecular organic material accounts for described dentistry tampon gross mass is 20%-0.05%, the mass percent that collagen accounts for described dentistry tampon gross mass is 10%-90%, and all the other compositions complement to 100%.
Compared with prior art, dentistry tampon of the present invention passes through drug hemostasis, and profile meets each crowd's tooth structure characteristics, it is disposable nontoxic aseptic dentistry hemostatic material, easy to use, simple to operate, have certain intensity, toughness and flexibility, can be made into the tampon of length different size model, be filled in the oral cavity in each gingiva cavity hemorrhage the hemostasis of gingiva wound surface and the repair that can cause exodontia.
The specific embodiment
For making the present invention easier to understand,, further set forth the present invention below in conjunction with specific embodiment.Should be understood that these embodiment only to be used to the present invention is described and be not used in and limit the scope of the invention.
Embodiment 1
A kind of dentistry tampon of present embodiment, form by collagen and chitosan, collagen is selected from the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, and the mass percent that collagen accounts for dentistry tampon gross mass is 90%, and all the other compositions complement to 100%.
Embodiment 2
A kind of dentistry tampon of present embodiment is made up of collagen, fibrin and hyaluronic acid, collagen is selected from the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, the mass percent that collagen accounts for dentistry tampon gross mass is 70%, and all the other compositions complement to 100%.The shape of tampon cooperates with the gingiva nest.The thickness of this tampon is 0.2cm, highly is 0.5cm, and width is 0.2cm, is fit to child, teenager use.
Embodiment 3
A kind of dentistry tampon of present embodiment is made up of collagen, sodium alginate and chitosan, collagen is selected from the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, the mass percent that collagen accounts for dentistry tampon gross mass is 60%, and all the other compositions complement to 100%.The shape of tampon cooperates with the gingiva nest, tampon be shaped as cone.This tampon is a medium size, its thickness 0.3cm, and height 1.5cm, width 0.4cm is fit to young and middle-aged the use.
Embodiment 4
A kind of dentistry tampon of present embodiment is made up of collagen, gelatin, alginic acid and cellulose, collagen is selected from the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, the mass percent that collagen accounts for dentistry tampon gross mass is 10%, the mass percent of cellulose comprises dentistry tampon gross mass is 20%, and all the other compositions complement to 100%.The shape of tampon cooperates with the gingiva nest, and is one-body molded.This tampon is a queen size, its thickness 0.6cm, and height 1.6cm, width 1.5cm is fit to elderly population and uses.
Embodiment 5
A kind of dentistry tampon of present embodiment is made up of collagen, sodium alginate and polyvinylpyrrolidone, collagen is selected from the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, the mass percent that collagen accounts for dentistry tampon gross mass is 90%, the mass percent that polyvinylpyrrolidone accounts for dentistry tampon gross mass is 0.05%, and all the other compositions complement to 100%.The shape of tampon cooperates with the gingiva nest.
Embodiment 6
A kind of dentistry tampon of present embodiment is made up of collagen, hyaluronic sodium salt and polyvinyl alcohol, collagen is selected from the active collagen in source such as muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail of cattle, the mass percent that collagen accounts for dentistry tampon gross mass is 85%, the mass percent that polyvinyl alcohol accounts for dentistry tampon gross mass is 5%, and all the other compositions complement to 100%.In another embodiment, polyvinyl alcohol can be replaced by politef.The shape of tampon cooperates with the gingiva nest.
Embodiment 7
A preferred embodiment of the preparation method of dentistry tampon of the present invention is after the raw material stirring of dentistry tampon is mixed, and typing and carry out lyophilization in mould obtains integrated dentistry tampon.The raw material of above-mentioned dentistry tampon comprises the described various situations as preceding embodiment 1-6.
Disposable dentistry tampon of the present invention carries out clinical 60 examples according to clinical trial regulation total, inclusion criteria is the dental patients of no other diseases, during use, open non-returnable container, embed gingiva nest after the exodontia with this tampon of tweezers gripping, slightly firmly push and make and closely contact with gingiva.Treat stop blooding fully back or after wound repair do not have pain of wound surface, can assist to take out by patient or doctor.Wherein the age is 8 examples below 10 years old, 11 years old to 18 years old patient's 13 examples, and 19 years old to 55 years old patient's 31 examples, the patient is 8 examples more than 56 years old.The specification that the dentistry hemostasis that the patient uses below 10 years old is calculated is 0.3cm, height 0.8cm, width 0.6cm as thickness, and 3min to 7.5min arrives haemostatic effect, and wherein 5 examples are 3.3min, and 2 examples are 5.2min, and 1 example is 7min; The specification of the tampon that used to 18 years old in 11 years old is 0.5cm, height 0.9cm, width 0.7cm as thickness, and bleeding stopping period is at 3～6min, and wherein 9 examples are 3.3min, and 2 examples are 4min, and 2 examples are 5.1min; The specification of the tampon that used to 55 years old in 19 years old is 0.6cm, height 1.2cm, width 1cm as thickness, and bleeding stopping period is at 3～5min, and wherein 25 examples are 3.6min, and 4 examples are 3.9min, and 2 examples are 4.3min; The specification of the tampon that the patient uses more than 56 years old is 0.5cm, height 1.3cm, width 1.2cm as thickness, and bleeding stopping period is at 4～6min, and wherein 6 examples are 4.1min, and 2 examples are 4.5min.Above-mentioned use result shows that this dentistry tampon haemostatic effect is good, and the hemostasis point is had quick repair, has avoided repeatedly hemorrhage, and is simple to operate, easy to use.Dentistry tampon of the present invention is applicable to quick-acting haemostatic powder and the reparation when gingiva wound surface that the each age group crowd caused because of dental caries or other any reasons cause having tooth pulled out is hemorrhage, can be used for family and hospital.
Last institute should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention but not limiting the scope of the invention; although the present invention has been done detailed description with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can make amendment or be equal to replacement technical scheme of the present invention, and not break away from the essence and the scope of technical solution of the present invention.
Claims (10)
1, a kind of dentistry tampon, it is characterized in that, described dentistry tampon comprises fibrous protein and polysaccharide, described fibrous protein comprises collagen, described collagen is the active collagen in muscle tendon, Corii Bovis seu Bubali, Corii Sus domestica, fish skin or the Mus tail source of cattle, and the mass percent that described collagen accounts for described dentistry tampon gross mass is 10%-90%.
2, dentistry tampon according to claim 1 is characterized in that, described dentistry tampon also comprises high-molecular organic material, and the mass percent that described high-molecular organic material accounts for described dentistry tampon gross mass is 0.05%-20%.
3, according to the described dentistry tampon of one of claim 1-2, it is characterized in that described fibrous protein also comprises fibrin or gelatin.
According to the described dentistry tampon of one of claim 1-2, it is characterized in that 4, described polysaccharide comprises chitosan, hyaluronic acid or its sodium salt, alginic acid or its sodium salt.
5, dentistry tampon according to claim 2 is characterized in that, described high-molecular organic material comprises cellulose, polyvinyl alcohol, polyvinylpyrrolidone or politef.
According to the described dentistry tampon of one of claim 1-2, it is characterized in that 6, the shape of described tampon cooperates with the gingiva nest.
7, according to the described dentistry tampon of one of claim 1-2, it is characterized in that, described tampon be shaped as cone.
8, according to the described dentistry tampon of one of claim 1-2, it is characterized in that described tampon is one-body molded.
According to the described dentistry tampon of one of claim 1-2, it is characterized in that 9, the thickness of described tampon is 0.2～0.6cm, highly is 0.5～1.6cm, and width is 0.2～1.5cm.
10, a kind of preparation method of dentistry tampon is characterized in that, after the raw material stirring of dentistry tampon was mixed, typing and carry out lyophilization in mould obtained integrated dentistry tampon.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910041914A CN101637623A (en) | 2009-08-18 | 2009-08-18 | Dental tampon and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910041914A CN101637623A (en) | 2009-08-18 | 2009-08-18 | Dental tampon and preparation method thereof |
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| CN101637623A true CN101637623A (en) | 2010-02-03 |
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| CN200910041914A Pending CN101637623A (en) | 2009-08-18 | 2009-08-18 | Dental tampon and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102228716A (en) * | 2011-06-25 | 2011-11-02 | 四川大学 | Collagen-polycaprolactone (PCL) dental hemostatic sponge and preparation method thereof |
| CN102247617A (en) * | 2011-07-01 | 2011-11-23 | 莫秀梅 | Medical adhesive or hemostatic |
| CN102247615A (en) * | 2011-06-25 | 2011-11-23 | 四川大学 | Gelatine-PCL (posterior cruciate ligament) dental hemostatic sponge and preparation method thereof |
| CN104368034A (en) * | 2014-11-14 | 2015-02-25 | 苏州蔻美新材料有限公司 | Collagen-based biological material and preparation method thereof |
| CN106139129A (en) * | 2016-08-08 | 2016-11-23 | 桂林市晟博科技服务有限公司 | A kind of haemostatic medicament and preparation method thereof |
| CN114288090A (en) * | 2021-12-30 | 2022-04-08 | 福建恒安卫生材料有限公司 | Preparation method of disposable hygienic product with oxygen slow release function |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3699965A (en) * | 1970-11-10 | 1972-10-24 | Int Playtex Corp | Tampon for absorbing body fluids |
| CN1905844A (en) * | 2003-11-24 | 2007-01-31 | 雷特拉克托托普有限公司 | Dental device and method for its use |
| CN101001649A (en) * | 2004-07-09 | 2007-07-18 | 弗罗桑公司 | Haemostatic composition comprising hyaluronic acid |
-
2009
- 2009-08-18 CN CN200910041914A patent/CN101637623A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3699965A (en) * | 1970-11-10 | 1972-10-24 | Int Playtex Corp | Tampon for absorbing body fluids |
| CN1905844A (en) * | 2003-11-24 | 2007-01-31 | 雷特拉克托托普有限公司 | Dental device and method for its use |
| CN101001649A (en) * | 2004-07-09 | 2007-07-18 | 弗罗桑公司 | Haemostatic composition comprising hyaluronic acid |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102228716A (en) * | 2011-06-25 | 2011-11-02 | 四川大学 | Collagen-polycaprolactone (PCL) dental hemostatic sponge and preparation method thereof |
| CN102247615A (en) * | 2011-06-25 | 2011-11-23 | 四川大学 | Gelatine-PCL (posterior cruciate ligament) dental hemostatic sponge and preparation method thereof |
| CN102247617A (en) * | 2011-07-01 | 2011-11-23 | 莫秀梅 | Medical adhesive or hemostatic |
| CN104368034A (en) * | 2014-11-14 | 2015-02-25 | 苏州蔻美新材料有限公司 | Collagen-based biological material and preparation method thereof |
| CN104368034B (en) * | 2014-11-14 | 2017-02-08 | 重庆紫郡农业发展有限公司 | Collagen-based biological material and preparation method thereof |
| CN106139129A (en) * | 2016-08-08 | 2016-11-23 | 桂林市晟博科技服务有限公司 | A kind of haemostatic medicament and preparation method thereof |
| CN114288090A (en) * | 2021-12-30 | 2022-04-08 | 福建恒安卫生材料有限公司 | Preparation method of disposable hygienic product with oxygen slow release function |
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Owner name: GUANGZHOU TRAUER BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: TONG GANG Effective date: 20120412 |
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Effective date of registration: 20120412 Address after: 510663, Guangdong, Guangzhou Science City, Xiangshan Road, No. 17, excellent science and Technology Park, block A, four Applicant after: Guangzhou Trauer Biotechnology Co., Ltd. Address before: 510663, Guangdong, Guangzhou Science City, Xiangshan Road, No. 17, excellent science and Technology Park, block A, four Applicant before: Tong Gang |
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Application publication date: 20100203 |