CN101621930A - 包含氟氯苯菊酯和氟啶蜱脲的杀虫倾注组合物 - Google Patents

包含氟氯苯菊酯和氟啶蜱脲的杀虫倾注组合物 Download PDF

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CN101621930A
CN101621930A CN200780005582A CN200780005582A CN101621930A CN 101621930 A CN101621930 A CN 101621930A CN 200780005582 A CN200780005582 A CN 200780005582A CN 200780005582 A CN200780005582 A CN 200780005582A CN 101621930 A CN101621930 A CN 101621930A
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composition
pours
flumethrin
desinsection
fluazuron
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CN101621930B (zh
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F·R·埃姆斯利
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Bayer Pharma AG
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Bayer Animal Health GmbH
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

本发明涉及一种对抗扁虱，特别是牛身上的扁虱的杀虫组合物，其具有氟氯苯菊酯和氟啶蜱脲作为其活性成分。除上述活性成分外，组合物可以包括N－甲基吡咯烷酮，一缩二丙二醇单甲醚和，任选地，染料作为载体和辅助剂。

Description

包含氟氯苯菊酯和氟啶蜱脲的杀虫倾注组合物
技术领域
本发明涉及一种杀虫组合物。
背景技术
可以获得很多化合物用于动物中的杀虫应用。在很多情况下，尤其对于防治扁虱，期望具有倾注(pour on)组合物。对于这类组合物而言，期望其具有良好的击倒(knockdown)和延长的持久性。然而，目前大部分可获得的组合物具有这些品质中的一种或另一种，很少两者兼具。
发明内容
发明目的
本发明的目的在于提供一种能够减轻上述问题的杀虫倾注组合物。
发明概述
根据本发明提供了一种杀虫倾注组合物，其特征在于，活性成分包括氟氯苯菊酯和氟啶蜱脲。
本发明的进一步的特征提供了含有9-11g/l氟氯苯菊酯和20-40g/l氟啶蜱脲的组合物，优选含有10g/l氟氯苯菊酯和25g/l氟啶蜱脲。
本发明的更进一步的特征提供了包括载体和辅助剂的组合物；对于这些可以包括N-甲基吡咯烷酮，一缩二丙二醇单甲醚(dipropylene glycol monomethylether)，以及任选地染料；以及包含196-241g/l，优选210-230g/l，特别优选215-225，特别是约218.8g/l的N-甲基吡咯烷酮；649-794g/l，优选670-771g/l，特别优选700-740g/l，特别是约721g/l的一缩二丙二醇单甲醚以及，以及任选地，0.09-0.11g/l，特别是0,10g/l的专利蓝染料。
下述实施例举例说明了根据本发明制备的杀虫倾注组合物的一个实施方案。
具体实施方式
实施例1
通过混合下述化合物制备杀虫倾注组合物：
氟氯苯菊酯*           10.0g/l
氟啶蜱脲*             25.0g/l
N-甲基吡咯烷酮        218.76g/l
一缩二丙二醇单甲醚    721.48g/l
专利蓝染料            0.1g/l
*假定氟氯苯菊酯和氟啶蜱脲的效力为100％的用量
当需要调整效力时，利用一缩二丙二醇单甲醚来补偿体积的变化。使用的一缩二丙二醇单甲醚以商品名″Dowanol DPM″销售。染料是任选的，当不使用染料时，用一缩二丙二醇单甲醚补足体积。
如.此得到的组合物可以用作对抗动物，特别是牛上的扁虱的倾注产品。优选的施用剂量，特别对于牛，是1ml/10kg，这等同于氟氯苯菊酯0.9-1.1mg/kg，优选1mg/kg；氟啶蜱脲2-4mg/kg，优选2.5mg/kg。其它施用剂量可能是适合的，这依赖于各个情形的情况。已经发现，所述组合物对于对抗牛蜱(Rhipicephalus(Boophilus)decoloratus)蓝色扁虱，比氟氯苯菊酯本身，提供了可比拟至改进的扁虱击倒和持久性，以及比氟啶蜱脲本身，提供了更长的持久性。已经发现，所述提高的持久性对抗拟除虫菊酯抗性(resistant)牛蜱(Rhipicephalus(Boophilus)decoloratus)蓝色扁虱至少是35天，对抗敏感型牛蜱(Rhipicephalus(Boophilus)decoloratus)蓝色扁虱至少是60天，这比经证明了的单独使用氟啶蜱脲对抗敏感型扁虱的48天更长。因此本发明组合物优于单独使用的这两种已知产品中的任何一个，这表明了意料不到的增效作用，因为在本发明的给药率表示氟啶蜱脲的施用率降低了16.7％。尽管目前还不知道该增效作用的该机理。
应该理解的是，存在该杀虫组合物的许多其他实施方案，其均落入本发明的范围，特别是关于所使用的活性化合物和赋形剂的浓度。任何合适的载体和辅助剂都可以以合适的浓度使用。

Claims (9)

1、一种杀虫倾注组合物，其特征在于，活性成分包括氟氯苯菊酯和氟啶蜱脲。
2、权利要求1所述的杀虫倾注组合物，其特征在于，组合物含有9-11g/l氟氯苯菊酯和20-40g/l氟啶蜱脲。
3、权利要求2所述的杀虫倾注组合物，其特征在于，组合物含有10g/l氟氯苯菊酯和25g/l氟啶蜱脲。
4、前述权利要求中任一项所述的杀虫倾注组合物，其特征在于，组合物还包括载体和/或辅助剂。
5、权利要求4所述的杀虫倾注组合物，其特征在于，载体和/或辅助剂选自：N-甲基吡咯烷酮，一缩二丙二醇单甲醚和染料。
6、权利要求5所述的杀虫倾注组合物，其特征在于，其含有196-241g/l N-甲基吡咯烷酮。
7、权利要求5或6所述的杀虫倾注组合物，其特征在于，其含有649-794g/l一缩二丙二醇单甲醚。
8、权利要求5-7中任一项所述的杀虫倾注组合物，其特征在于，其含有0.09-0.11g/l专利蓝染料。
9、权利要求1-8所述的杀虫倾注组合物，其比得上目前可获得的类似组合物，其对抗牛上的牛蜱(Rhipicephalus(Boophilus)decoloratus)蓝色扁虱提供了改进的击倒和改进的持久性。
CN200780005582.0A 2006-02-17 2007-02-14 包含氟氯苯菊酯和氟啶蜱脲的杀虫倾注组合物 Expired - Fee Related CN101621930B (zh)

Applications Claiming Priority (3)

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ZA200601411 2006-02-17
ZA2006/01411 2006-02-17
PCT/EP2007/001257 WO2007093393A2 (en) 2006-02-17 2007-02-14 Pesticidal pour-on composition comprising flumethrin and fluazuron

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CN101621930A true CN101621930A (zh) 2010-01-06
CN101621930B CN101621930B (zh) 2016-10-05

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AR (1) AR059519A1 (zh)
AU (1) AU2007214652B2 (zh)
BR (1) BRPI0707846B1 (zh)
MX (1) MX2008010451A (zh)
NZ (1) NZ570512A (zh)
UY (1) UY30168A1 (zh)
WO (1) WO2007093393A2 (zh)
ZA (1) ZA200807935B (zh)

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EP3760045A1 (en) * 2019-07-04 2021-01-06 Laboratorios Virbac Mexico SA DE CV Topical composition against rhipicephalus (boophilus) microplus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU568003B2 (en) * 1984-02-24 1987-12-10 Pitman-Moore Australia Limited Cyhalothrin and iki 7899 mixtures

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11511152A (ja) * 1995-08-16 1999-09-28 バイエル・アクチエンゲゼルシヤフト ピレスロイド類および昆虫の発生阻害剤を含む活性化合物の組合わせ
AU2003100144B4 (en) * 2003-02-28 2004-03-04 Jurox Pty Ltd Lousicide composition
AU2005100403B4 (en) * 2005-05-13 2005-09-01 Jurox Pty Ltd Parasiticide Composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU568003B2 (en) * 1984-02-24 1987-12-10 Pitman-Moore Australia Limited Cyhalothrin and iki 7899 mixtures

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BRPI0707846A2 (pt) 2011-05-10
BRPI0707846B1 (pt) 2016-02-23
AU2007214652B2 (en) 2013-05-16
CN101621930B (zh) 2016-10-05
WO2007093393A3 (en) 2008-11-27
UY30168A1 (es) 2007-09-28
WO2007093393A2 (en) 2007-08-23
AU2007214652A1 (en) 2007-08-23
NZ570512A (en) 2011-10-28
ZA200807935B (en) 2009-11-25
MX2008010451A (es) 2008-11-12

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