CN101530372A - Blow molding medical container - Google Patents

Blow molding medical container Download PDF

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Publication number
CN101530372A
CN101530372A CN200810086522A CN200810086522A CN101530372A CN 101530372 A CN101530372 A CN 101530372A CN 200810086522 A CN200810086522 A CN 200810086522A CN 200810086522 A CN200810086522 A CN 200810086522A CN 101530372 A CN101530372 A CN 101530372A
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China
Prior art keywords
container
blow molding
shoulder
main part
ratio
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Pending
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CN200810086522A
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Chinese (zh)
Inventor
小野泽英树
鹫见武彦
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Kyoraku Co Ltd
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Kyoraku Co Ltd
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Application filed by Kyoraku Co Ltd filed Critical Kyoraku Co Ltd
Priority to CN200810086522A priority Critical patent/CN101530372A/en
Publication of CN101530372A publication Critical patent/CN101530372A/en
Pending legal-status Critical Current

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  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)

Abstract

The invention relates to such medical containers as an infusion solution container for gathering infusion solution used for intravenous injection and infusion solution dropping upon the insertion of needle into a rubber stopper, in particular to a light blow molding medical container with excellent transparency, softness and shock resistance. The blow molding medical container is formed by extrusion and blow molding of propylene random copolymer resin and has a mouth part with a flange, a head part under the mouth part, a shoulder part connected with the head part, a main body part being approximately flat at the up and down direction, a bottom part under the main body part and a freely bending suspension piece positioned on the bottom part for suspending the container. The structural parts are integrally formed, the ratio (h2/h1) between the height sum h2 of the head part and the shoulder part and the height h1 of the main body part is 20 percent to 50 percent, and the ratio (volume/resin content) between the volume and the content of resin forming the container is within a range from 20 to 50.

Description

Blow molding medical container
Technical field
The present invention relates to place the transfusion liquid of used for intravenous injection, on rubber stopper, insert pin and medical containers such as infusion vessel that transfusion liquid is dripped, relate in particular to the blow molding medical container of the lightweight and the transparency, flexibility and excellent impact resistance.
Background technology
Below, in the medical containers such as infusion vessel of the transfusion liquid that places used for intravenous injection, come the classification declaration conventional art according to the manufacture method of synthetic resin material.
In the past, place the known container and the plastic container that glass is arranged of medical containers such as infusion vessel of the transfusion liquid of used for intravenous injection.Plastic medical container is known a container that is called as the bag of the bag shape of the periphery welding of two films, and at the container of the blow molding of blow molding mould internal shaping three-dimensional shape.And above-mentioned blow molding medical container can pass through resin is shaped through biaxial stretch-formed injection-blow molding, or is shaped by the extrusion blow molding of the parison direct forming after will pushing.
Injection-blow molding is shaped the requirement of system medical container when being discharged from the container transfusion liquid, begin to finishing and discharging equably from drop, and transfusion liquid residual few in container, therefore develop the container that a kind of main part at container is provided with rib, so that when the intrinsic pressure minimizing of container, the easy and regular property of wall of a container ground distortion (the open CN85107756A of Chinese patent).
In addition, also developed a kind of projection of utilizing as the vestige of the injection port that when injection moulding, produces, the container (the Japanese Patent Laid bulletin is put down into 2-6535) of the Suspension of container has been installed.
On the other hand, the extrusion blow molding container is shaped unlike injection-blow molding needs injection-molded mould and two kinds of moulds of blow molding mould, only use the advantage that the blow molding mould just can direct forming and have, also have in addition in the bottom of container can integrally formed bending Suspension freely advantage (the Japanese Patent Laid bulletin is put down into 5-10947).
Patent documentation 1: the open CN85107756A of Chinese patent
Patent documentation 2: the Japanese Patent Laid bulletin is put down into 2-6535
Patent documentation 3: the Japanese Patent Laid bulletin is put down into 5-10947
The problem points of conventional art below is described.
The injection-blow molding forming containers utilize biaxial stretch-formed have can mass production the advantage of the good container of the transparency.Opposite is to need complicated and large-scale former such as die device, heater, stretch orientation device.
The injection-blow molding forming containers intention of patent documentation 1 record is, by constituting rib, realizes that the container wall deforms when discharging the medicinal liquid that places.The container that constitutes this kind rib has medicinal liquid to a certain extent and discharges the easy feature that becomes, but the small characteristic variations of the resin of thick distribution of wall of a container and formation container all might be destroyed the discharge effect of above-mentioned medicinal liquid.
The cast gate that the injection-blow molding forming containers of patent documentation 2 records produces when utilizing injection moulding can be installed Suspension simply.But, when Suspension is installed, in will operation, because the variation of the position of small melting condition setting tool causes producing the deviation of installation strength as the end fusion fusing of the projection of cast gate.The in-problem goods of installation strength appear sometimes.
The extrusion blow molding container purpose of patent documentation 3 record is, by determining to constitute the resin of container and the Thickness Distribution of container above-below direction, with the orthostatic that satisfies container simultaneously and discharge property naturally of medicinal liquid.But, reach above-mentioned described Thickness Distribution in order to stablize, need to improve the precision of creating conditions, the minor variations of creating conditions just may be damaged effect.
According to the requirement of resources effective utilization and lightization of product weight, all require lighting for any container of injection-blow molding forming containers and extrusion blow molding container.But, have some problems in the development requires of light-weighted raising.
That is, because with the container thin-walled property, heat affecting causes the problem that produces distortion or shrink when existing because of decline that appearance that small uneven thickness causes the pin hole in the chamber wall, resistance to impact occur or sterilization etc.
Summary of the invention
The inventor carries out various researchs, the result makes up with optimal condition by the material that will constitute container, the modular construction and the shape of container, lightweight, the transparency, excellent heat resistance have been found, simultaneously the blow molding medical container of thickness homogeneous and excellent impact resistance.
The blow molding medical container that the invention of the present invention the 1st aspect relates to is characterised in that, by being that the random copolymer resin extrusion blow constitutes with propylene, has the oral area that is formed with flange, be positioned at the stem of oral area below, the shoulder that is connected with stem, main part in the above-below direction general planar, be positioned at the bottom of main part below and the Suspension that is positioned at the free bend that container is sling of bottom, structure member shown in above-mentioned is integrally formed, the height summation h2 of stem and shoulder is 20~50% divided by the main part of the height h1 of main part than (h2/h1), and volume is 20~50 with respect to the ratio (volume/amount of resin) of the amount of resin that constitutes container.
The blow molding medical container that the invention of the present invention the 2nd aspect relates to is the blow molding medical container affiliated as the invention of the 1st aspect, wherein, the main part of container is 1.4~1.8 at the flat ratio (width of the width/fore-and-aft direction of left and right directions) of cross section.
The blow molding medical container that the invention of the present invention the 3rd aspect relates to is the described blow molding medical container of invention as the 1st or 2 aspects, wherein, the enlarging rate of shoulder wall (height of the hole enlargement parts of the horizontal wide/shoulder of the hole enlargement part of shoulder) is 0.3~0.9 on the container fore-and-aft direction.
Below explanation constitutes the definition and the meaning of the technological project of feature of the present invention.
(1) resin material
Propylene is that random copolymer is the random copolymer of propylene (80~99 weight %) and alpha-olefin (20~1 weight %), and preferred MFR (melt flow rate (MFR), melt flow rate) is 1~20, more preferably 2~5 polymer.By MFR being set in the above-mentioned scope, vertical wall unevenness and the bad order of prolonging when preventing to be shaped, thus even obtain also can not being out of shape, rotten container at the temperature heat sterilization more than 11 ℃.MFR is to be the value that benchmark records with JIS-K7210 (230 ℃, 216Kg load).
The propylene that constitutes container is that the extrusion blow molding of random copolymer resin is good, and the transparency is good simultaneously, and to compare flexibility good with the propylene based block copolymer.Suspension and bending section are integrally formed among the present invention.In such structure, the above-mentioned material of softness and alternating bending characteristic good is the most suitable.
In addition, the above-mentioned material material of starting point in 105 ℃~170 ℃ scope that preferably except that having above-mentioned characteristic, flow.By as above setting mobile starting point, can obtain blow molding good, be maintained and confirm content and the necessary transparency, the container of the hinge characteristic good of indeformable and Suspension in sterilization process.
The bending that container the is sling Suspension freely that is positioned at the bottom is that to utilize extrusion head extruding be the resin that random copolymer forms by propylene, afterwards when blow molding, shaping can obtain the good container of durability that Suspension can not rupture by this by the hinge of mould compression.
(2) main part ratio
As the essential factor of the global shape that determines container, the relation of stem, shoulder and main part is extremely important.Among the present invention, the summation h2 of the height of stem and the shoulder main part after divided by main part h1 is set in 20~50% than (h2/h1).
Transmission power when in order to make container being cased is near to greatest extent, and the oral area of the extrusion blow molding container shown in injection-blow molding forming containers shown in the patent documentation 1 and the patent documentation 3 and the height of shoulder and the height of main part are in a ratio of the shortest state.For example, the main part of the container shown in patent documentation 1 and the patent documentation 2 than (h2/h1) in about 15~18% scope.Such mode is difficult to obtain the thin and uniform container of wall thickness of integral container wall.That is, among the present invention,, can obtain the thin and uniform container of thickness of integral container wall, can guarantee maximum volume with the amount of resin of minimum by main part is set in 20~50% than (h2/h1).
(3) volumetric ratio
Volumetric ratio among the present invention is meant the amount of filling with of container (when placing medicinal liquid in the container, is reached the amount of brimmer.The cc of unit) (unit is gram divided by the amount of resin that constitutes container.Remove the amount of resin of cock body and Suspension) ratio (amount of filling with/amount of resin).For the injection-blow molding forming containers, form the volumetric ratio below 18 usually so that the wall of drawn orientation is indeformable when heat sterilization.Among the present invention,, constitute specific shape, can reach 20~50 volumetric ratio, can enough few amount of resin pack constant medicinal liquid with material specific in the medical containers such as transfusion by extrusion blow molding.It is particularly useful when particularly the present invention is small containers such as 100ml or 250ml for the amount of placing of making medicinal liquid.
Volumetric ratio is to be to form the every use of container 1g resin with the numeric representation, can form the volume of the container of what degree.The big more expression of numerical value can obtain the container of constant volume with few more material.That is the lighting progress of expression container.The above-mentioned volumetric ratio of injection-blow molding shaping system medical container is generally less than 20.Infer that its reason is to extend the pass that is orientated and fasten the distortion that uneven thickness, heat cause or the generation of contraction owing to injection-blow molding is shaped in order to prevent.
(5) flat ratio
Among the present invention, flat ratio is represented the ratio (Da/Db) of the width D a of left and right directions divided by the width D b of fore-and-aft direction.If not flat in general, stable the dripping property when then medicinal liquid is discharged is bad.But, if flat ratio is too high container when upright, can not stably be stood, perhaps might cause the generation of wall unevenness, pin hole because of the variation of blow-up ratio.The invention is characterized in that flat ratio is 1.4~1.8.By such structure, can obtain the container of the excellent in stability of the discharge of medicinal liquid when upright.
(6) enlarging rate
The enlarging rate of shoulder wall is meant: as shown in Figure 2, in the shoulder face shaping at the front of container and the back side, mensuration from the boundary portion x of stem (the 2nd stem) and shoulder 4 to shoulder 4 with the boundary portion y of main part 5 above-below direction record apart from xy, in above-mentioned scope apart from xy, with the distance D after the shoulder hole enlargement divided by distance xy's and ratio (D/xy).
For the injection-blow molding forming containers, must improve blow-up ratio and equably stretch orientation therefore need the enlarging rate more than 1.2 usually to improve intensity.But for extrusion blow molding, the shape that above-mentioned enlarging rate is big can produce thinner wall section, even pin hole can occur, and is therefore undesirable.Since this reason, preferred in the present invention 0.3~0.9.Fig. 2 of embodiment has shown that enlarging rate is about 0.4 shoulder shape.
Usually, the violent change of shape of the high expression of enlarging rate.Violent change of shape causes the variation of violent blow-up ratio.Among the present invention, be prerequisite, can stably do not have the shaping of pin hole or extreme wall unevenness, and can realize the volumetric ratio expected with resin and forming process.The common enlarging rate of injection-blow molding shaping system medical container is about 1.2.That is, enlarging rate is higher than the present invention.Infer that its reason is for resin stretched orientation being improved the cause of blow-up ratio.
Description of drawings
Fig. 1 is the front view of the container that the present invention relates to.
Fig. 2 is the right view of the container that the present invention relates to.
Fig. 3 is the upward view of the container that the present invention relates to.
Fig. 4 is with put upside down the upward view of the container that the present invention relates to of state of Suspension.
Fig. 5 is the container that the present invention relates to of explanation and the figure of the shape comparison of conventional example.
The specific embodiment
Each structure of the container that the present invention relates to and the meaning of above-mentioned each structure below are described.
Among Fig. 1~Fig. 4,1 is the container that the present invention relates to, and is specially the medical containers such as infusion vessel of the transfusion liquid that places used for intravenous injection.Container 1 possesses: be formed with the oral area 2 of flange, the stem 3 that is positioned at oral area below, the shoulder 4 that is connected with stem, the main part 5 of above-below direction general planar, be positioned at main part below bottom 6 and be positioned at bottom the bending that container is sling Suspension 7 freely.And the container flange 2a of container 2, stem 3, shoulder 4, main part 5, bottom 6 and Suspension 7 are shaped integratedly by extrusion blow molding, thereby constitute one.
The 8th, inside is filled with the elastomeric cock bodys such as rubber that can insert entry needle.Cock body 8 below have cock body flange 8a, have pulling-on piece 8b up.Cock body 8 is with cock body flange 8a and container flange 2a butt and utilize the heat welded method to install under the state that pressurizes.Pulling-on piece 8b is the parts that are used for seal opening device that are called as draw ring, when extraction is captured in medicinal liquid in the container, can hook pulling-on piece 8b tractive with finger, makes the top opening of oral area, and entry needle is inserted the elastomer that is filled in the cock body 8, and medicinal liquid is extracted out.
Stem 3 has columned the 1st stem 3a, be positioned at the below of above-mentioned the 1st stem 3a outwards outstanding cyclic rib 3b, be positioned at cylindric the 2nd stem 3c of the below of above-mentioned cyclic rib 3b.Container 1 needs carrying, encapsulates each operation line such as oral area operation sterilization process vanning operation to check the operation filling work procedure through the forming process of container, therefore.During carrying, the mechanical holding assembly in the last operation keeps the 1st stem 3a, and holding assembly keeps the 2nd stem 3c in one operation of back.Like this, carry out the transmission of each operation shown in above-mentioned.
Shoulder 4 is parts that thin stem 3 is connected with flat and thick main part.
Main part 5 is the flat parts in the approaching cross section in the front and the back side.Main part 5 has par 5a from container profile depression with the back in front, has the end difference 5b of crescent shape in the boundary portion with shoulder 4, has the end difference 5c of crescent shape in the boundary portion with bottom 6.Main part 5 about two sides have the side end 5d of the face that is almost parallel up and down.Par 5a can sell labeing of points for attention that producer handles etc. as the kind of the medicinal liquid that places of expression and expression portion such as pay.
Bottom 6 is shapes of lower end band circle, has when container 1 erect with erectility and the contacted mounting surface 6a of mounting portion such as desk and two placed side 6a clamp about quilt part have recess 6b.Suspension 7 has and is used for container 1 is hung over opening 7a on the suspension apparatus in ward etc. and the hinge 7b that Suspension 7 is connected bottom 6.Suspension 7 utilize crooked freely hinge 7b and link into an integrated entity with the recess 7b of bottom 6.And Suspension 7 becomes the state of Fig. 4 that front or the back side overwhelms from the state of Fig. 3.
During the use of container, spin upside down, utilize Suspension to extract medicinal liquid out from oral area with the state of slinging from the state of Fig. 1.

Claims (3)

1. a blow molding medical container is characterized in that,
By being that the random copolymer resin extrusion blow molding constitutes with propylene,
Possess: be formed with flange oral area, be positioned at the stem of oral area below, is connected with stem setting shoulder, the main part of general planar on the above-below direction, be positioned at the bottom below the main part and be positioned at bottom the bending that container is sling Suspension freely,
Structure member shown in above-mentioned is shaped integratedly, and the height summation h2 of stem and shoulder is that h2/h1 is 20~50% divided by the main part ratio of the height h1 gained of main part, and volume is 20~50 with respect to the ratio of the amount of resin that constitutes container.
2. blow molding medical container as claimed in claim 1 is characterized in that,
The main part of container is that the width of the width/fore-and-aft direction of left and right directions is 1.4~1.8 at the flat ratio of cross section.
3. blow molding medical container as claimed in claim 1 or 2 is characterized in that,
The enlarging rate of the shoulder wall on the container fore-and-aft direction is that the hole enlargement height partly of the hole enlargement transverse width/shoulder partly of shoulder is 0.3~0.9.
CN200810086522A 2008-03-14 2008-03-14 Blow molding medical container Pending CN101530372A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200810086522A CN101530372A (en) 2008-03-14 2008-03-14 Blow molding medical container

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200810086522A CN101530372A (en) 2008-03-14 2008-03-14 Blow molding medical container

Publications (1)

Publication Number Publication Date
CN101530372A true CN101530372A (en) 2009-09-16

Family

ID=41101369

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200810086522A Pending CN101530372A (en) 2008-03-14 2008-03-14 Blow molding medical container

Country Status (1)

Country Link
CN (1) CN101530372A (en)

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Application publication date: 20090916