CN101522144A - Temperature control device and thermal sensor assembly for medical device - Google Patents
Temperature control device and thermal sensor assembly for medical device Download PDFInfo
- Publication number
- CN101522144A CN101522144A CNA2007800384207A CN200780038420A CN101522144A CN 101522144 A CN101522144 A CN 101522144A CN A2007800384207 A CNA2007800384207 A CN A2007800384207A CN 200780038420 A CN200780038420 A CN 200780038420A CN 101522144 A CN101522144 A CN 101522144A
- Authority
- CN
- China
- Prior art keywords
- temperature control
- control equipment
- distributor chamber
- chamber housing
- heat sensor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
- A61M5/445—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media the media being heated in the reservoir, e.g. warming bloodbags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0612—Eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1413—Modular systems comprising interconnecting elements
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a dispensing assembly (205) has a dispensing chamber housing (425), a temperature control device (450), a thermal sensor (460), and an interface (530). The dispensing chamber housing has an inner surface, an outer surface, and a wall thickness. The inner surface partially defines a dispensing chamber (405) for receiving a quantity of a substance. The temperature control device at least partially surrounds the dispensing chamber housing. The temperature control device alters a temperature of a substance in the dispensing chamber. The temperature control device and the thermal sensor are located on a substrate. The substrate is wrapped around an exterior surface of the dispensing chamber housing. The interface is connected to the temperature control device and the thermal sensor. An interface connector (520) is connected to the interface. The distance between the temperature control device and the thermal sensor is approximately equal to the wall thickness of the dispensing chamber housing.
Description
The application is the part continuation application of the U.S. Patent application No.11/581591 of the U.S. Patent application No.11/581629 that submitted on October 16th, 2006, the U.S. Patent application No.11/581630 of submission on October 16th, 2006, submission on October 16th, 2006, and relevant with the U.S. Patent application No.11/435906 that submitted on May 17th, 2006.
Technical field
The present invention relates to the medical treatment device that a kind of single uses, more specifically, the present invention relates to a kind of double-body bike ophthalmic injection device with disposable aspiration needle end, this disposable aspiration needle end comprises temperature control equipment and temperature sensor assembly.
Background technology
The some diseases and the situation of eyes back segment constitute a threat to vision.Age-related macular degeneration (ARMD), choroidal neovascularization (CNV), retinopathy are (for example, diabetic renal papillary necrosis, vitreoretinopathy), to infect (for example, giant cell (CMV) viral infection), uveitis, macular edema, glaucoma and optic neuropathy be wherein several examples for retina virus.
By being expelled in the eyes, medicine can treat these and other disease.Typically adopt traditional syringe and pin manually to carry out this injection.Fig. 1 is the perspective view that is used for injecting medication into the existing syringe in the eyes.In Fig. 1, syringe comprises pin 105, Lu Eshi hub 110, chamber 115, piston 120, piston rod 125 and thumb post 130.Just as is known, injected medicine to be arranged in chamber 115.Promoting thumb post 130 makes piston 120 make medicine pass through pin 105 discharges.
When using this syringe, need the surgeon with being needled into eye tissue, keeping syringe steady and activating syringe piston (under nurse's help or do not need nurse's help), to inject a fluid in the eyes.The amount of being injected is not typically controlled with accurate way, because read the influence that scale is subjected to parallax.Fluid flow is uncontrolled.And because " unsettled " injection can cause tissue damage.When eyes remove pin, also the medicine adverse current occurring.
People have made great efforts to attempt to control the conveying of small amount of liquid.The ULTRA that the EFD company in the Providence city that commercial available fluid distributor is a Rhode Island,USA produces
TMThe SF allotter.The ULTRA allotter typically is used in the distribution of a small amount of industry adhesive.This allotter utilizes traditional syringe and distribution syringe needle commonly used.Adopt motor and actuating fluid to activate syringe piston.Adopt such allotter, the amount of being carried highly depends on fluid viscosity, surface tension and specific distribution syringe needle.Cleveland, the ParkerHannifin company of Ohio have issued the small amount of liquid allotter that drug development is used that is used for by Aurora instrument level control (LLC) the company manufacturing in Santiago, California.The Parker/aurora allotter has utilized the piezoelectricity distributor gear.Although this allotter is accurate, this allotter is very expensive and the signal of telecommunication need be transported to distributor gear.
U.S. Patent No. 6290690 discloses a kind of ophthalmic system that is used for viscous fluid (for example silicone oil) is expelled to eyes, this ophthalmic system simultaneously at intra-operative with the form of fluid/fluid exchange from second kind of viscous fluid of eyes sucking-off (for example perfluorocarbon liquid), break away from or break with repairing retina.This system comprises the conventional syringe with piston.One end of this syringe and pneumatic pressure source fluid coupled, this pneumatic pressure source provides constant Pneumatic pressure, with power piston.The other end of syringe is via pipeline and infusion cannula fluid coupled, to carry the viscous fluid that will inject.
Need a kind of portable hand-held device (handpiece) that is used for injecting medication in the eyes.This hander can comprise the limited number of time repeated use assembly that can be attached to disposable aspiration needle portion and remove from disposable aspiration needle portion.This disposable aspiration needle portion comprises medicine, be used for the pin of administration and be used to change the temperature control equipment (for example heater) of the temperature of medicine.Assembling for the ease of device need be integrated in temperature control equipment and heat sensor in the single component.
Summary of the invention
In a embodiment, the invention provides a kind of allocation component with distributor chamber housing, temperature control equipment and heat sensor according to principle of the present invention.This distributor chamber housing has inner surface, outer surface and certain wall thickness.Be defined for to described inner surface portion the distributor chamber of admitting a certain amount of material.Temperature control equipment to small part is surrounded the distributor chamber housing.Described temperature control equipment is used for changing the temperature at the material of described distributor chamber.Temperature control equipment and heat sensor all are positioned on the substrate.
In another embodiment, the invention provides a kind of monomer temperature Control Component according to principle of the present invention.This monomer temperature Control Component comprises heat sensor and the temperature control equipment that is positioned on the substrate.Heat sensor is substantially equal to distance between the material that described temperature control equipment and its temperature will change by described temperature control equipment being arranged such that on the described substrate in the distance between described heat sensor and the described temperature control equipment.
In another embodiment according to principle of the present invention, the invention provides a kind of allocation component, this allocation component comprises distributor chamber housing, temperature control equipment, heat sensor and composition surface.This distributor chamber housing has inner surface, outer surface and certain wall thickness.Be defined for to described inner surface portion the distributor chamber of admitting a certain amount of material.Temperature control equipment to small part is surrounded described distributor chamber housing.Described temperature control equipment is used for changing the temperature of the material of described distributor chamber.Temperature control equipment and heat sensor are positioned on the described substrate.Described composition surface is connected with described heat sensor with described temperature control equipment.The composition surface connector is connected with described composition surface.Distance between described temperature control equipment and described heat sensor is substantially equal to the described wall thickness of described distributor chamber housing.Described substrate is around the outer surface parcel of described distributor chamber housing.
Be appreciated that above-mentioned describe, in general terms and following detailed description only are exemplary and indicative, and aim to provide desired further explanation of the present invention.Below other advantage of the present invention and purpose are set forth and have been hinted in description and practice of the present invention.
Description of drawings
Incorporate in this description and constitute a part of the present invention description of drawings several embodiments of the present invention, this accompanying drawing also comes together to explain principle of the present invention with description.
Fig. 1 is the perspective view of existing syringe.
Fig. 2 is the view that principle according to the present invention comprises the ophthalmic medical devices of disposable aspiration needle portion and limited number of time repeated use assembly.
Fig. 3 is the embodiment that reuses assembly according to the limited number of time of principle of the present invention.
Fig. 4 is the cross sectional view according to the disposable aspiration needle portion of principle of the present invention and limited number of time repeated use assembly.
Fig. 5 is the cross sectional view according to the disposable aspiration needle portion of principle of the present invention.
Fig. 6 A and 6B are the cross sectional view according to the distributor chamber housing unit of principle of the present invention.
Fig. 7 A and 7B are according to the temperature control equipment of principle of the present invention and the view of thermal sensor assembly.
The specific embodiment
Now the exemplary embodiment of the present invention shown in the accompanying drawing is described in detail.In whole accompanying drawing, adopt identical Reference numeral to represent same or analogous parts as far as possible.
Fig. 2 has described a view of ophthalmic medical devices according to an embodiment of the invention, and this ophthalmic medical devices comprises disposable aspiration needle portion and limited number of time repeated use assembly.In Fig. 2, this medical treatment device comprises needle section 205 and limited number of time repeated use assembly 250.Needle section 205 comprises pin 210, housing 215 and optional luminous body 275.Limited number of time is reused assembly 250 and is comprised housing 255, switch 270, locking mechanism 265 and threaded portion 260.
Switch 270 is suitable for providing input to this system.For example, can adopt switch 270 to come starting system or heater.The control input that other switch, button or user handle is known and can reuses assembly 250 and/or needle section 205 uses with limited number of time.
When preparing to use needle section 205, optional luminous body 275 is illuminated.Optional luminous body 275 can stretch out from housing 215, and perhaps it can be accommodated in the housing 215, under optional luminous body 275 is accommodated in situation in the housing 215, can see optional luminous body 275 by the transparent part of housing 215.In other embodiments, can replace optional luminous body 275 with indicator (for example liquid crystal display, segment displays or the state of indication disposable aspiration needle portion 205 or other device of condition).For example, optional luminous body 275 also can intermittently pulse with indicate other state (such as but not limited to system mistake, battery be full of fully, battery is not full of fully or reuse connection fault between the assembly 250 at needle section 205 and limited number of time).Although shown optional luminous body 275 or other indicator are set on the needle section 205, it also can be set at limited number of time and reuse on the assembly 250.
Fig. 3 is another embodiment that reuses assembly according to the limited number of time of principle of the present invention.Limited number of time is reused assembly 250 and is comprised button 310, display 320 and housing 330.Disposable aspiration needle portion 205 is attached to limited number of time and reuses on the end 340 of assembly 250.Button 310 activated, to be provided to the input of system.Utilize switch 270, button 310 can start heater or other temperature control equipment or can cause the actuating of piston.Display 320 is that liquid crystal display, segment displays or indication disposable aspiration needle portion 205 or limited number of time are reused the state of assembly 250 or other device of condition.
Fig. 4 is that disposable aspiration needle portion and limited number of time are reused the cross sectional view of assembly according to an embodiment of the invention.Fig. 4 shows needle section 205 and reuses the mode that assembly 250 engages with limited number of time.In the embodiment of Fig. 4, needle section 205 comprises plunger interface 420, piston 415, distributor chamber housing 425, needle section housing 215, temperature control equipment 450, heat sensor 460, pin 210, distributor chamber 405, composition surface 530 and tip interface connector 520.Limited number of time is reused assembly 250 and is comprised mechanical links 545, actuator rod 510, actuator 515, power supply 505, controller 305, limited number of time repeated use assembly housing 255, composition surface 535 and limited number of time repeated use assembly composition surface connector 525.
In needle section 205, plunger interface 420 is positioned at an end of piston 415.The other end of piston 415 forms an end of distributor chamber 405.Piston 415 is suitable for sliding in distributor chamber 405.Make the inner surface fluid-tight of the outer surface and the distributor chamber housing 425 of piston 415.Distributor chamber housing 425 surrounds distributor chamber 405.Typically, distributor chamber housing 425 has drum.For example, distributor chamber 405 also has drum.
The parts of needle section 205 (comprising distributor chamber housing 425, temperature control equipment 450 and piston 415) to small part is sealed by needle section housing 215.In an embodiment consistent, the piston 415 and the inner surface of distributor chamber housing 425 are sealed with principle of the present invention.This sealing stops the pollution that is accommodated in any material in the distributor chamber 405.When being used for medical purpose, this sealing needs.Sealing can be positioned at any point place on piston 415 or the distributor chamber housing 425.
Reuse in the assembly 250 at limited number of time, power supply 505 provides electric power for actuator 515.Composition surface (not shown) between power supply 505 and actuator 515 is used to actuator 515 that the pipeline of electric power is provided.Actuator 515 is connected with actuator rod 510.When actuator 515 was stepper motor, actuator rod 510 was integrally formed with actuator 515.Mechanical linkage 545 is connected with actuator rod 510.In this structure, when actuator 515 makes actuator rod 510 when pin 210 moves up, mechanical linkage 545 also moves up towards pin 210.
As previously mentioned, needle section 205 is suitable for reusing with limited number of time that assembly 250 cooperates or is attached.In the embodiment of Fig. 5, be positioned at plunger interface 420 on the basal surface of piston 415 and be suitable for and be positioned near the mechanical linkage 545 that limited number of time reuses the top surface of assembly housing 255 and cooperate.In addition, tip interface connector 520 is suitable for being connected with limited number of time repeated use assembly composition surface connector 525.When needle section 205 by this way when limited number of time is reused assembly 250 and is connected, actuator 515 and actuator rod 510 are suitable for towards pin 210 driven plunger 415 that makes progress.In addition, between controller 305 and temperature control equipment 450, form a composition surface.Signal can be reused assembly composition surface connector 525, tip interface connector 520 and composition surface 530 slave controllers 305 by composition surface 535, limited number of time and be sent to temperature control equipment 450.
In operation, when needle section 205 and limited number of time were reused assembly 250 and be connected, controller 305 was controlled the operation of actuators 515.Actuator 515 activated and makes actuator rod 510 to move up towards pin 210.Then, the mechanical linkage 545 that cooperates with plunger interface 420 makes piston 415 move up towards pin 210.Then, the material that is arranged in distributor chamber 405 is discharged by pin 210.
In addition, the operation of controller 305 control temperature control equipments 450.Temperature control equipment 450 is suitable for heating and/or chilled distribution chamber housing 425.Because distributor chamber housing 425 to small part is a heat conductivity, heating or chilled distribution chamber housing 425 make heating or cooling be arranged in the material of distributor chamber 405.Temperature information can be transferred to controller 305 from heat sensor 460 via any in a plurality of different interface configurations.Can adopt this temperature information to control the operation of temperature control equipment 450.When temperature control equipment 450 was heater, controller 305 controls were sent to the magnitude of current of temperature control equipment 450.The magnitude of current that is sent to temperature control equipment 450 is big more, and it is hot more that temperature control equipment becomes.Adopt this mode, controller 305 can adopt the operation that is used to control from the feedback circuit of the information of heat sensor 460 temperature control equipment 450.Can adopt the control algolithm (for example PID (PID) algorithm) of any adequate types to control the operation of temperature control equipment 450.
Fig. 5 is the cross sectional view that is used for the disposable aspiration needle portion of ophthalmic medical devices according to an embodiment of the invention.In Fig. 5, disposable aspiration needle portion 205 comprises housing 215, pin 210, piston 415, plunger interface 420, distributor chamber 405, distributor chamber housing 425, temperature control equipment 450, heat sensor 460, composition surface 530 and tip interface connector 520.Disposable aspiration needle portion 205 operates as disposable syringe device.
In the embodiment of Fig. 5, piston 415 is arranged in distributor chamber housing 425.Distributor chamber 405 is assigned with chamber housing 425 and piston 415 sealings.Piston 415 forms fluid-tight with the inner surface of distributor chamber housing 425.Pin 210 and distributor chamber 405 fluid coupled.Adopt this mode, piston can contact the material that is arranged in distributor chamber 405 and it is released pin 210.Temperature control equipment 450 is with distributor chamber housing 425 adjacent layouts and to small part encirclement distributor chamber 405.The outer housing that housing 215 forms in the disposable aspiration needle portion 205.
In each embodiment of the present invention, temperature control equipment 450 is heating and/or chiller.Temperature control equipment 450 forms thermo-contact with distributor chamber housing 425.Like this, temperature control equipment 450 can change the temperature of the material in the distributor chamber 405.Composition surface 530 and tip interface connector 520 connect temperature control equipment 450 and limited number of time repeated use assembly.In this case, temperature control equipment 450 is reused assembly by limited number of time and is powered and control.In one embodiment of the invention, temperature control equipment 450 is reused the assembly received current via composition surface 530 from limited number of time.Provide electric current to make temperature control equipment 450 heating along the direction positive voltage of device (promptly by).The negative voltage of device (promptly by) provides electric current to make temperature control equipment 450 coolings in opposite direction.
The material (typically being medicine) that is transported in the eyes is arranged in distributor chamber 405.Adopt this mode, this material is touched by the inner surface of distributor chamber housing 425 and a face of piston 415.Typically, distributor chamber 405 is shaped as cylindrical shape.Temperature control equipment 450 forms thermo-contact with distributor chamber housing 425.Adopt this mode, temperature control equipment 450 is suitable for controlling the temperature of the contents of distributor chamber 425.Heat sensor 460 provides temperature information, with the operation of assist control temperature control equipment 450.
In one embodiment of the invention, the material that is arranged in distributor chamber 405 is the medicine that is loaded into distributor chamber in advance.In this case, disposable aspiration needle portion 205 is suitable as single and uses consumable goods.Pack into when this disposable products can assemble in the factory medicine of doses.
When medicine is loaded in the distributor chamber 405 in advance, the medicine of lading clearance amount in advance.For example, the medicine of 100 microlitres can be loaded in the distributor chamber 405, and can distribute the nearly any amount of 100 microlitres.In this case, piston 415 can be moved an accurate distance, so that the medicine of exact dose is carried by pin 210 and to eyes from distributor chamber 405.This provides the convenience of the motility and the assembling of administration.
Fig. 6 A is the cross sectional view according to the distributor chamber housing unit of principle of the present invention.In Fig. 6, the shape of distributor chamber housing 425 is columnar generally.Distributor chamber 405 is positioned at the intracavity that is limited by the inner surface of distributor chamber housing 425 to small part.Temperature control equipment 450 to small part is surrounded distributor chamber housing 425.Temperature control equipment 450 and heat sensor 460 are integrated into single component, and this single component is around the outer surface parcel of distributor chamber housing 425.In one embodiment of the invention, heat sensor 460 is critesistor.
Fig. 6 B is the cross sectional view according to the distributor chamber housing unit of principle of the present invention.This view is the horizontal cross-section of the embodiment of Fig. 6 A (it is a vertical section).In Fig. 6 B, the distributor chamber housing has circular generally cross section (because it is drum generally).The thickness of the wall of distributor chamber housing is " d ".Distributor chamber 405 is positioned at distributor chamber housing 425.Temperature control equipment 450 to small part is surrounded distributor chamber housing 425.Temperature sensor 460 adjacent settings with the distributor chamber housing.
Fig. 7 A has described temperature control equipment and thermal sensor assembly according to an embodiment of the invention.In Fig. 7 A, temperature control equipment 450 is disposed on the substrate (for example, flexible print wiring board or similar structures), as shown in the figure.In its form of simplifying most, temperature control equipment is to work as electric current by producing the resistive element of heat at that time.Heat sensor 460 is positioned on the same substrate with temperature control equipment 450.Composition surface 530 and tip interface connector 520 are used for making temperature control equipment 450 and heat sensor 460 to be connected to limited number of time and reuse on the assembly.
Fig. 7 B is the guide wire of alternative shape of temperature control equipment and the heat sensor of Fig. 7 A.In Fig. 7 B, show the configuration of heat sensor 460 and temperature control equipment 450.Heat sensor 460 is configured to apart from temperature control equipment 450 1 distance ' ' d ' '.This distance ' ' d ' ' is substantially equal to the thickness of distributor chamber housing 425, shown in Fig. 6 B.Adopt this mode, heat sensor 460 reads a temperature, and this temperature is substantially equal to the temperature inside of distributor chamber housing 425.Because distance ' ' d ' ' is the distance between temperature control equipment 450 and heat sensor 460 and the distributor chamber 405, reads a temperature so heat sensor 460 is oriented to it, this temperature is similar to the temperature in the distributor chamber 405.
According to above be appreciated that the invention provides a kind of be used for will be accurately the mass transport of amount to the improved system of eyes.The disposable delivery device needle portion that the invention provides that the single of the medicine that can carry doses uses.This needle section is reused assembly with limited number of time and is engaged.Disposable aspiration needle portion has the assembly that comprises temperature control equipment and heat sensor.The structure of this assembly makes and manufacturing and the assembling of being convenient to this device has realized reliable injection process simultaneously.
Although described the present invention in conjunction with the opthalmological conveyer device that single uses, the present invention includes any medical treatment device or injection device.According to description of the present invention disclosed herein and practical operation, other embodiments of the invention are obvious to those skilled in the art.Description and example are only as exemplary, and true scope of the present invention and spirit are pointed out by claims.
Claims (20)
1. allocation component, this allocation component comprises:
The distributor chamber housing, this distributor chamber housing has inner surface, outer surface and certain wall thickness; Be defined for to described inner surface portion the distributor chamber of admitting a certain amount of material;
Temperature control equipment, this temperature control equipment are positioned on the substrate and to small part and surround described distributor chamber housing, and described temperature control equipment is used for changing the temperature at the material of described distributor chamber; And
Be positioned at the heat sensor on the described substrate.
2. allocation component according to claim 1, wherein, the shape of described distributor chamber housing is cylindrical shape generally.
3. allocation component according to claim 1, wherein, the distance between described temperature control equipment and described heat sensor is substantially equal to the described wall thickness of described distributor chamber housing.
4. allocation component according to claim 1 also comprises:
The composition surface that is connected with described heat sensor with described temperature control equipment; With
The composition surface connector that is connected with described composition surface.
5. allocation component according to claim 4 wherein, offers described temperature control equipment by described composition surface with electric power.
6. allocation component according to claim 4, wherein, temperature information spreads out of from described heat sensor by described composition surface.
7. allocation component according to claim 1, wherein, described heat sensor is a critesistor.
8. allocation component according to claim 1, wherein, described temperature control equipment is the heater that comprises resistive element.
9. allocation component according to claim 1 also comprises:
Pin with described distributor chamber fluid coupled.
10. allocation component according to claim 1, wherein, described substrate is around the outer surface parcel of described distributor chamber housing.
11. a monomer temperature Control Component, this monomer temperature Control Component comprises:
Substrate;
Be positioned at the temperature control equipment on the described substrate;
Be arranged in the heat sensor on the described substrate, make to be substantially equal to distance between the material that described temperature control equipment and its temperature will change by described temperature control equipment in the distance between described heat sensor and the described temperature control equipment.
12. monomer temperature Control Component according to claim 11 also comprises:
The composition surface that is connected with described heat sensor with described temperature control equipment; With
The composition surface connector that is connected with described composition surface.
13. monomer temperature Control Component according to claim 11, wherein, described heat sensor is a critesistor.
14. monomer temperature Control Component according to claim 11, wherein, described temperature control equipment is the heater that comprises resistive element.
15. an allocation component, this allocation component comprises:
The distributor chamber housing, this distributor chamber housing has inner surface and outer surface, is defined for to described inner surface portion the distributor chamber of admitting a certain amount of material, and described distributor chamber housing has certain wall thickness;
Temperature control equipment, this temperature control equipment are positioned on the substrate and surround described distributor chamber housing to small part, and described temperature control equipment is used for changing the temperature of the material of described distributor chamber;
Be positioned at the heat sensor on the described substrate;
The composition surface that is connected with described heat sensor with described temperature control equipment; And
The composition surface connector that is connected with described composition surface;
Wherein, the distance between described temperature control equipment and described heat sensor is substantially equal to the described wall thickness of described distributor chamber housing, and wherein said substrate is around the outer surface parcel of described distributor chamber housing.
16. allocation component according to claim 15, wherein, the shape of described distributor chamber housing is cylindrical shape generally.
17. allocation component according to claim 15 wherein, offers described temperature control equipment by described composition surface with electric power.
18. allocation component according to claim 15, wherein, temperature information spreads out of from described heat sensor by described composition surface.
19. allocation component according to claim 15, wherein, described heat sensor is a critesistor.
20. allocation component according to claim 15, wherein, described temperature control equipment is the heater that comprises resistive element.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58159106A | 2006-10-16 | 2006-10-16 | |
| US58163006A | 2006-10-16 | 2006-10-16 | |
| US58162906A | 2006-10-16 | 2006-10-16 | |
| US11/581,591 | 2006-10-16 | ||
| US11/581,630 | 2006-10-16 | ||
| US11/581,629 | 2006-10-16 | ||
| PCT/US2007/080078 WO2008108886A2 (en) | 2006-10-16 | 2007-10-01 | Temperature control device and thermal sensor assembly for medical device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101522144A true CN101522144A (en) | 2009-09-02 |
| CN101522144B CN101522144B (en) | 2011-04-13 |
Family
ID=39721774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007800384207A Expired - Fee Related CN101522144B (en) | 2006-10-16 | 2007-10-01 | Temperature control device and thermal sensor assembly for medical device |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JP5215313B2 (en) |
| KR (1) | KR20090091714A (en) |
| CN (1) | CN101522144B (en) |
| AU (1) | AU2007348610B2 (en) |
| BR (1) | BRPI0717160A2 (en) |
| CA (1) | CA2666924C (en) |
| MX (1) | MX2009003825A (en) |
| WO (1) | WO2008108886A2 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103339483A (en) * | 2010-12-02 | 2013-10-02 | 雀巢产品技术援助有限公司 | Low-inertia thermal sensor in a beverage machine |
| CN105771031A (en) * | 2016-04-01 | 2016-07-20 | 国网安徽省电力公司培训中心 | Insulin pump suitable for all-weather use |
| CN107106772A (en) * | 2014-11-18 | 2017-08-29 | 伊莱利利公司 | Hot locking mechanism for delivery device |
| US10335163B2 (en) | 2013-03-05 | 2019-07-02 | Depuy Ireland Unlimited Company | Polymer 4-in-2 femoral cutting instrument having separable A/P and chamfer cutting blocks |
| CN110124154A (en) * | 2019-04-24 | 2019-08-16 | 浙江科技学院 | Vaccine needle |
| US12076025B2 (en) | 2022-05-11 | 2024-09-03 | DePuy Synthes Products, Inc. | Polymer cutting block |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8372036B2 (en) | 2009-05-06 | 2013-02-12 | Alcon Research, Ltd. | Multi-layer heat assembly for a drug delivery device |
| US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
| JP2016503669A (en) * | 2012-12-13 | 2016-02-08 | メディコム イノベーション パートナー エイ／エス | Detection device and injection device including the same |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4910158Y1 (en) * | 1969-09-30 | 1974-03-11 | ||
| JPS58500928A (en) * | 1981-05-04 | 1983-06-09 | ソ−ラ−・エナ−ジ−・テクノロジ−・インコ−ポレ−テツド | Root canal occlusion syringe |
| HU196265B (en) * | 1986-04-11 | 1988-10-28 | Rolitron Mueszaki Fejlesztoe K | Method and apparatus for producing flow of wanted temperature of a physiological solution, as well as temperature control method and a heating device for the previously mentioned method and apparatus |
| DE69216485T2 (en) * | 1991-06-26 | 1997-07-17 | Ppg Industries Inc | Electrochemical sensor construction |
| CA2129284C (en) * | 1993-11-24 | 1999-03-09 | Kenneth J. Niehoff | Controlling plunger drives for fluid injection in animals |
| US5690614A (en) * | 1995-09-06 | 1997-11-25 | Microwave Medical Systems, Inc. | Microwave apparatus for warming low flow rate infusates |
| US6290690B1 (en) | 1999-06-21 | 2001-09-18 | Alcon Manufacturing, Ltd. | Simultaneous injection and aspiration of viscous fluids in a surgical system |
| US6259074B1 (en) * | 1999-10-26 | 2001-07-10 | Sims Level 1, Inc. | Apparatus for regulating the temperature of a fluid |
| KR100350576B1 (en) * | 2000-04-14 | 2002-08-30 | 박 군 | Warmer for medical treatment and its control method |
| US6882797B2 (en) * | 2003-03-26 | 2005-04-19 | Gaymar Industries, Inc. | Multiple plate fluid warmer unit |
| KR100577406B1 (en) * | 2003-09-17 | 2006-05-10 | 박재상 | Heater and the method for producing the same using pcb |
| JP2006136417A (en) * | 2004-11-10 | 2006-06-01 | Univ Of Electro-Communications | Medicament injector and medicament injection method |
| JP2006271953A (en) * | 2005-03-03 | 2006-10-12 | U Corporation | Warming device of tube for air sending or solution sending |
| US20060217740A1 (en) * | 2005-03-25 | 2006-09-28 | Alcon, Inc. | Tip assembly |
-
2007
- 2007-10-01 KR KR1020097010164A patent/KR20090091714A/en not_active Application Discontinuation
- 2007-10-01 JP JP2009533424A patent/JP5215313B2/en not_active Expired - Fee Related
- 2007-10-01 CN CN2007800384207A patent/CN101522144B/en not_active Expired - Fee Related
- 2007-10-01 CA CA2666924A patent/CA2666924C/en not_active Expired - Fee Related
- 2007-10-01 AU AU2007348610A patent/AU2007348610B2/en not_active Ceased
- 2007-10-01 MX MX2009003825A patent/MX2009003825A/en not_active Application Discontinuation
- 2007-10-01 BR BRPI0717160-9A patent/BRPI0717160A2/en not_active IP Right Cessation
- 2007-10-01 WO PCT/US2007/080078 patent/WO2008108886A2/en active Application Filing
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103339483A (en) * | 2010-12-02 | 2013-10-02 | 雀巢产品技术援助有限公司 | Low-inertia thermal sensor in a beverage machine |
| CN103339483B (en) * | 2010-12-02 | 2015-10-07 | 雀巢产品技术援助有限公司 | Low inertia thermal sensor in beverage machine |
| US10335163B2 (en) | 2013-03-05 | 2019-07-02 | Depuy Ireland Unlimited Company | Polymer 4-in-2 femoral cutting instrument having separable A/P and chamfer cutting blocks |
| US11234711B2 (en) | 2013-03-05 | 2022-02-01 | Depuy Ireland Unlimited Company | Polymer 4-in-2 femoral cutting instrument having separable A/P and chamfer cutting blocks |
| CN107106772A (en) * | 2014-11-18 | 2017-08-29 | 伊莱利利公司 | Hot locking mechanism for delivery device |
| CN107106772B (en) * | 2014-11-18 | 2020-03-27 | 伊莱利利公司 | Thermal locking mechanism for a drug delivery device |
| CN105771031A (en) * | 2016-04-01 | 2016-07-20 | 国网安徽省电力公司培训中心 | Insulin pump suitable for all-weather use |
| CN110124154A (en) * | 2019-04-24 | 2019-08-16 | 浙江科技学院 | Vaccine needle |
| CN110124154B (en) * | 2019-04-24 | 2021-08-03 | 浙江科技学院 | Vaccine needle |
| US12076025B2 (en) | 2022-05-11 | 2024-09-03 | DePuy Synthes Products, Inc. | Polymer cutting block |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007348610A1 (en) | 2008-09-12 |
| WO2008108886A2 (en) | 2008-09-12 |
| KR20090091714A (en) | 2009-08-28 |
| CN101522144B (en) | 2011-04-13 |
| BRPI0717160A2 (en) | 2013-10-15 |
| CA2666924C (en) | 2015-06-16 |
| AU2007348610B2 (en) | 2012-06-28 |
| MX2009003825A (en) | 2009-05-12 |
| WO2008108886A3 (en) | 2008-11-20 |
| JP5215313B2 (en) | 2013-06-19 |
| JP2011501973A (en) | 2011-01-20 |
| CA2666924A1 (en) | 2008-09-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101522144B (en) | Temperature control device and thermal sensor assembly for medical device | |
| CN101534759B (en) | Ophthalmic injection device including dosage control device | |
| EP2197398B1 (en) | Temperature control device and thermal sensor assembly for medical device | |
| US20080234625A1 (en) | Fuse Assembly For Single Use Medical Device | |
| US20100069842A1 (en) | Ceramic Chamber With Integrated Temperature Control Device For Ophthalmic Medical Device | |
| US7740619B2 (en) | Spring driven ophthalmic injection device with safety actuator lockout feature | |
| US20080197035A1 (en) | Sharps Container System for Two Piece Injection Device | |
| US20090177182A1 (en) | Glass Drug Chamber For Automated Ophthalmic Injection Device | |
| EP2187850B1 (en) | Thermal coefficient driven drug pellet size for ophthalmic injection | |
| WO2008115270A2 (en) | Ophthalmic injection device including dosage control device | |
| US20090227979A1 (en) | Drug Level Sensor for Injection Device | |
| AU2008311080A1 (en) | Method of delivering a rate and temperature - dependent substance into the eye |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110413 Termination date: 20201001 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |