CN101474364A - Chinese medicinal oral wine for treating vitiligo - Google Patents

Abstract

The invention discloses a Chinese medicine oral vinum for the treatment of vitiligo, which has medicinal materials as follows: 20-100 parts of zaocys dhumnade, 15-75 parts of gastrodia elata, 5-50 parts of radix sileris, 5-35 parts of cinnamon, 6-60 parts of white puncture vine, 6-24 parts of cortex acanthopanacis, 5-25 parts of notopterygium incisium, 5-55 parts of achyranthes, 6-34 parts of fructus aurantii, 25-75 parts of prepared rhizome of rehmannia, 5-40 parts of angelica dahurica, 15-65 parts of ligustrum lucidum and 15-65 parts of cortex dictamni. The invention is a pure Chinese medicine preparation that is safe and reliable with the medicinal materials available, free from toxic side effect, short in treatment time and high in therapeutic effect as well as that not only can remove lung heat, expel wind and free lung, but also can invigorate blood, dissolve stasis, free lung channel, protect lung, ameliorate kidney and strengthen spleen, therefore, the invention can take effect stably with high cure rate and can radically cure the vitiligo in free from relapse.

Description

The leukodermic extract oral medicated wine of a kind of treatment

Technical field

The invention belongs to medical technical field, be specifically related to the leukodermic extract oral medicated wine of a kind of treatment.

Background technology

According to clinical observation, vitiligo starts from child and teenager usually, and only about half of patients with vitiligo was fallen ill before 20 years old, and incidence rate descends with age.Report according to related data, the vitiligo sickness rate is 1% in the U.S., and Denmark is 0.38%, and the Ursula of India is specially for 1.13%, Calcutta is 0.46%, dermatosis generaI investigation in northeast village finds that leukodermic crowd's incidence rate is 0.09%-0.15% in China, and the area, Nanjing is 0.29%, and the area, Shanghai is 0.54%, Hubei is 0.5%-1%, Jinan, Shandong is unexpectedly up to 2.7%, this may with people's life, factors such as dietary habit and working environment are relevant.

Motherland's medical science is to start with from etiology and pathogenesis to leukodermic understanding, and dialectical demonstration is diagnosed and treated, and main pattern of syndrome has (1) disharmony between QI and blood card, (2) deficiency of the liver and kindey card, (3) congestion retardance card etc.

The leukodermic method of western medical treatment is many, and each method all has certain curative effect.Up to the present, also do not have a kind of western medicine therapy can cure various, all kinds of, each phase vitiligo, but its each therapy all has the shortcoming and defect that can not more get over comprehensively:

The beauty treatment means are treated leukodermic shortcoming: be not suitable for active stage vitiligo and general property therapy for vitiligo, because it can not suppress leukodermic continuation diffusion, also can't cure vitiligo simultaneously.

The cortex class because of the leukodermic shortcoming of pure therapy for treating is: 1, stop oral and medicine for external use after, cause recurrence easily; 2, have potential serious consequence, cause a day bacterium property femur head necrosis as meeting, its curative effect also is difficult to determine; 3, also diseases such as steroid atrophy, hypercortisolism, acne, telangiectasis can take place.

The leukodermic shortcoming of PUVA therapy for treating is: have certain bad reflection, as dizziness, feel sick, vomit, skin pruritus, the distortion of lymphocytes such as local edema and vesicle.

Surgery epidermic grafting therapy for treating vitiligo, its shortcoming are to be only limited to segmental and limitation vitiligo, and patient's skin lesion is limited in non-acra position, can not treat or treat failure to the vitiligo at acra position.At all can't therapeutic advance and general property vitiligo, and sequela can often take place, and causes the skin spot as meeting, all treats vitiligo and may.

Melanocyte In vitro culture transplantation effect attracts people's attention, but shortcoming is the long crinite position of body surface to be transplanted be difficult for successfully, and costly.

The autoplastic shortcoming of melanocyte is: to osteoarthrosis knuckle face, graft is difficult for surviving, and therapeutic domain utmost point limitation can not all be cured vitiligo.

Band melanocyte epidermis is cultivated its shortcoming of autotransplantation treatment vitiligo: the melanocyte disease of transplanting survival can not cover white macula fully, plantation point intersection still can be left over down white macula, cost height, workload are big, the technical operation difficulty is big, injecting cell concentration is difficult to inject according to everyone body constitution requirement accurately, the expense of patient's payment is also quite high, and its treatment time is also long.

Summary of the invention

The objective of the invention is for overcoming disadvantages of background technology, and provide a kind of treatment time short, taking convenience, dosage is little and can effect a radical cure leukodermic extract oral medicated wine.

To achieve these goals, the technical solution used in the present invention is: the leukodermic extract oral medicated wine of a kind of treatment is characterized in that containing the raw material of following weight portion:

Zaocys 20-100 part Rhizoma Gastrodiae 15-75 part Radix Saposhnikoviae 5-50 part Cortex Cinnamomi 5-35 part

Fructus Atriplicis Sibiricae 6-60 part Cortex Acanthopancis 6-24 part Rhizoma Et Radix Notopterygii 5-25 part Radix Achyranthis Bidentatae 5-55 part

Fructus Aurantii 6-34 part Radix Rehmanniae Preparata 25-75 part Radix Angelicae Dahuricae 5-40 part Fructus Ligustri Lucidi 15-65 part

Cortex Dictamni 15-65 part.

Optimized technical scheme of the present invention is: the leukodermic extract oral medicated wine of a kind of treatment is characterized in that containing the raw material of following weight portion:

Zaocys 30-90 part Rhizoma Gastrodiae 20-60 part Radix Saposhnikoviae 10-40 part Cortex Cinnamomi 10-30 part

Fructus Atriplicis Sibiricae 10-50 part Cortex Acanthopancis 10-20 part Rhizoma Et Radix Notopterygii 10-20 part Radix Achyranthis Bidentatae 10-50 part

Fructus Aurantii 10-30 part Radix Rehmanniae Preparata 30-60 part Radix Angelicae Dahuricae 10-30 part Fructus Ligustri Lucidi 20-60 part

Cortex Dictamni 20-60 part.

Described weight portion can be weight metering units such as gram, two, jin, kilogram, ton.

The present invention is complete, and the side has dispelling wind and removing obstruction in the collateral, and lung moistening is regulated the flow of vital energy, and collateral dredging is had one's ideas straightened out, and protects the liver kidney tonifying, consolidates and sets upright, activating blood circulation, the effect of the white secondary color of dispelling.

The present invention compared with prior art has the following advantages: the invention belongs to pure Chinese medicinal preparation, safe and reliable, the medicine source is easy to get, and has no side effect, treatment time is short, the curative effect height, can remove lung-heat, the lung qi dispersing that dispels the wind, again can blood circulation promoting and blood stasis dispelling, logical lung meridian, protect the liver, kidney tonifying, spleen invigorating, its curative effect is rapid, and can stablize and take effect, the cure rate height, non-relapse after healing can be effected a radical cure various vitiligo.

The specific embodiment

Following examples medical material all restrains by measurement unit.

Embodiment 1

The used medical material of present embodiment is Zaocys 20g, Rhizoma Gastrodiae 15g, Radix Saposhnikoviae 5g, Cortex Cinnamomi 5g, Fructus Atriplicis Sibiricae 6g, Cortex Acanthopancis 6g, Rhizoma Et Radix Notopterygii 5g, Radix Achyranthis Bidentatae 55g, Fructus Aurantii 34g, Radix Rehmanniae Preparata 75g, Radix Angelicae Dahuricae 40g, Fructus Ligustri Lucidi 65g, Cortex Dictamni 65g.

The preparation technology of present embodiment is: take by weighing the medical material of respectively distinguishing the flavor of by above-mentioned weight, concoct qualified after, put into the Porcelain Jar that fills 500-1000ml fermented wine (being aging Chinese liquor), sealing is soaked, stir 1-2 every day, soaks after 7-15 days, filtration is bottled and is got final product.

Embodiment 2

The used medical material of present embodiment is Zaocys 100g, Rhizoma Gastrodiae 75g, Radix Saposhnikoviae 50g, Cortex Cinnamomi 35g, Fructus Atriplicis Sibiricae 60g, Cortex Acanthopancis 24g, Rhizoma Et Radix Notopterygii 25g, Radix Achyranthis Bidentatae 5g, Fructus Aurantii 6g, Radix Rehmanniae Preparata 25g, Radix Angelicae Dahuricae 5g, Fructus Ligustri Lucidi 15g, Cortex Dictamni 15g.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 3

The used medical material of present embodiment is Zaocys 60g, Rhizoma Gastrodiae 45g, Radix Saposhnikoviae 30g, Cortex Cinnamomi 20g, Fructus Atriplicis Sibiricae 33g, Cortex Acanthopancis 15g, Rhizoma Et Radix Notopterygii 15g, Radix Achyranthis Bidentatae 30g, Fructus Aurantii 20g, Radix Rehmanniae Preparata 50g, Radix Angelicae Dahuricae 25g, Fructus Ligustri Lucidi 40g, Cortex Dictamni 40g.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 4

The used medical material of present embodiment is Zaocys 30g, Rhizoma Gastrodiae 20g, Radix Saposhnikoviae 10g, Cortex Cinnamomi 10g, Fructus Atriplicis Sibiricae 10g, Cortex Acanthopancis 10g, Rhizoma Et Radix Notopterygii 10g, Radix Achyranthis Bidentatae 50g, Fructus Aurantii 30g, Radix Rehmanniae Preparata 60g, Radix Angelicae Dahuricae 30g, Fructus Ligustri Lucidi 60g, Cortex Dictamni 60g.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 5

The used medical material of present embodiment is Zaocys 90g, Rhizoma Gastrodiae 60g, Radix Saposhnikoviae 40g, Cortex Cinnamomi 30g, Fructus Atriplicis Sibiricae 50g, Cortex Acanthopancis 20g, Rhizoma Et Radix Notopterygii 20g, Radix Achyranthis Bidentatae 10g, Fructus Aurantii 10g, Radix Rehmanniae Preparata 30g, Radix Angelicae Dahuricae 10g, Fructus Ligustri Lucidi 20g, Cortex Dictamni 20g.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 6

The used medical material of present embodiment is Zaocys 60g, Rhizoma Gastrodiae 40g, Radix Saposhnikoviae 25g, Cortex Cinnamomi 20g, Fructus Atriplicis Sibiricae 30g, Cortex Acanthopancis 15g, Rhizoma Et Radix Notopterygii 15g, Radix Achyranthis Bidentatae 30g, Fructus Aurantii 20g, Radix Rehmanniae Preparata 45g, Radix Angelicae Dahuricae 20g, Fructus Ligustri Lucidi 40g, Cortex Dictamni 40g.

The preparation technology of present embodiment is with embodiment 1.

Usage and dosage: every day 3 times, each 5-10ml, the each clothes at most of build overweight people 10-15ml, child below 15 years old obeys 5-7ml at every turn and gets final product, and a week all can take effect, and 2 months is a course of treatment, and cure 1-3 the course of treatment.

Curative effect determinate standard:

Recovery from illness: white macula all disappears, and recovers the normal colour of skin.

Produce effects: white macula partly disappears or dwindles, and the area that recovers the normal colour of skin accounts for skin lesion area 〉=50%.

Effectively: white macula partly disappears or dwindles, and the area that recovers the normal colour of skin accounts for skin lesion area 〉=10%,＜50%.

Invalid: white macula no change or dwindle, the area that recovers the normal colour of skin accounts for skin lesion area＜10%.

Clinical data of the present invention: the clinical observation case is totally 170 examples, and wherein 119 examples are organized in treatment, matched group 51 examples.Treatment group: male 68 examples, woman: 51 examples, minimal ages 15 years old, maximum 58 years old age.Course of disease 24-48 month 32 examples, 49-72 month 45 examples, 73-100 month 28 examples, 14 examples more than 100 months.Oral the present invention " Feng Yu dispel white first medicated wine of returning " is organized in treatment, takes every day 3 times, and each oral 5-10ml, the overweight people takes maximum 10-15ml at every turn, and 2 months is a course of treatment, shared 1-2 course of treatment.Matched group: male 36 examples, women 15 examples, minimal ages 23 years old, maximum 48 years old age, course of disease 24-48 month 17 examples, 49-72 month 31 examples, 73-100 month 3 examples.The matched group oral dexamethasone, every day 3 times, 1-2 month continuously, 1 of hormone successively decreased in every 2-4 week in the back of taking effect.During to 1 of next day clothes, the next day of adding 6-mp or phosphamide 2, generally kept 3-6 month.

Table 1 liang group sex age distribution situation

Group	The example number	The man	The woman
				The treatment group	119	68(57.14％)	51(42.86％)
Matched group	51	36(70.59％)	15(29.41％)

Table 2 liang group is sick plants national standard: two type distribution situations

Table 3 liang group is sick plants national standard: two class distribution situations

Table 4 liang group curative effect situation contrast

Group	The example number	Cure	Produce effects	Effectively	Invalid	Total effective rate
							The treatment group	119	90.76％	8.4％	0.84％	0％	100％
Matched group	51	17.64％	31.37％	25.5％	25.5％	74.5％

Clinical observation case 170 examples of the present invention, 119 examples are organized in treatment, matched group 51 examples.Treatment group and matched group general curative effect compare, and its result is: treatment is organized in 119 examples, cures 108 examples, accounts for 90.76%.Produce effects 10 examples account for 8.4%, and effective 1 example accounts for 0.84%, and invalid 0 example accounts for 0%, and total effective rate is 100%.In matched group 51 examples, cure 9 examples, account for 17.67%; Produce effects 16 examples account for 31.37%; Effective 13 examples account for 25.5%; Invalid 13 examples account for 25.59%, total effective rate 74.5%.There were significant differences for two groups of comparison curative effects.

Claims (2)

1, the leukodermic extract oral medicated wine of a kind of treatment is characterized in that containing the raw material of following weight portion:

Zaocys 20-100 part Rhizoma Gastrodiae 15-75 part Radix Saposhnikoviae 5-50 part Cortex Cinnamomi 5-35 part

Fructus Atriplicis Sibiricae 6-60 part Cortex Acanthopancis 6-24 part Rhizoma Et Radix Notopterygii 5-25 part Radix Achyranthis Bidentatae 5-55 part

Fructus Aurantii 6-34 part Radix Rehmanniae Preparata 25-75 part Radix Angelicae Dahuricae 5-40 part Fructus Ligustri Lucidi 15-65 part

Cortex Dictamni 15-65 part.

2, the leukodermic extract oral medicated wine of a kind of treatment according to claim 1 is characterized in that containing the raw material of following weight portion:

Zaocys 30-90 part Rhizoma Gastrodiae 20-60 part Radix Saposhnikoviae 10-40 part Cortex Cinnamomi 10-30 part

Fructus Atriplicis Sibiricae 10-50 part Cortex Acanthopancis 10-20 part Rhizoma Et Radix Notopterygii 10-20 part Radix Achyranthis Bidentatae 10-50 part

Fructus Aurantii 10-30 part Radix Rehmanniae Preparata 30-60 part Radix Angelicae Dahuricae 10-30 part Fructus Ligustri Lucidi 20-60 part

Cortex Dictamni 20-60 part.