CN101474105B - Parallel type electrostatic filature blood vessel support collector - Google Patents
Parallel type electrostatic filature blood vessel support collector Download PDFInfo
- Publication number
- CN101474105B CN101474105B CN2008102043491A CN200810204349A CN101474105B CN 101474105 B CN101474105 B CN 101474105B CN 2008102043491 A CN2008102043491 A CN 2008102043491A CN 200810204349 A CN200810204349 A CN 200810204349A CN 101474105 B CN101474105 B CN 101474105B
- Authority
- CN
- China
- Prior art keywords
- capillary tube
- filature
- blood vessel
- solution
- electrostatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Abstract
The invention relates to a parallel type electrostatic spinning intravascular stent collector which comprises a solution flow-velocity controlling device, a solution pipeline, a solution tank, a nozzle, a scale oscillometer, a stander, a motor and a capillary roller collector, wherein, the motor is fixed on the stander, and the output end of a rotating shaft of the motor is connected with the capillary roller collector; the scale oscillometer is connected with the solution flow-velocity controlling device which is connected with the solution tank; and one end of the solution pipeline positioned on the solution flow-velocity controlling device is inserted into the solution tank and connected with the nozzle. When the parallel type electrostatic spinning intravascular stent collector is used for collecting electrostatic spinning intravascular stent fibers, the hollow intravascular stent fibers with the diameter of 2-3mm can be produced through the parallel distribution of the capillaries and the rotating-speed regulation of the roller collector, and the hollow intravascular stent fibers can be ensured to be very even due to the telescopic function of the scale oscillometer.
Description
Technical field
The invention belongs to the tissue engineering bracket field, relate to a kind of spinning equipment, particularly relate to a kind of electrostatic filature blood vessel support collector.
Background technology
Adopting electrospinning device to prepare intravascular stent is to adopt the form of capillary tube catcher to receive.Resulting static spinning membrane is arranged and is covered on the capillary tube with the form of non-woven fabrics, can obtain the capillary blood pipe holder of hollow by the tubular type extracting method.Have many uses general, the present research of electrostatic spinning technique in making up tissue engineering bracket at present concentrates in the selection of electrostatic spinning membrane material mostly, also is the focus of research for the exploration of morphosis.Because the particularity of vascular morphology, the control of its aperture and epidermal thickness and adjusting are difficult points always; The intravascular stent that how can obtain mass simultaneously under identical sample preparation condition also is a very significant job.Preparation meet the human vas aperture the electrostatic filature blood vessel support structure, and the intravascular stent that under identical sample preparation condition, obtains mass be the important step of sample tissue engineering.
In the research about electrostatic filature blood vessel support collector, there are some documents to mention the structure of electrostatic filature blood vessel support and the relativity problem of gathering-device, as:
As document Satoru Kidoaki, Il Kuen Kwon, Takehisa Matsuda.Biomacromolecules.2005,26,37-46 has invented a kind of method of collecting multilamellar electrostatic filature blood vessel support fiber, obtains the electrostatic filature blood vessel support that diameter is the hollow of 3mm by the rotating speed of regulating the capillary tube catcher.
Document C.M.Vaz, S.van Tuijl, C.V.C.Bouten, F.P.T.Baaijens.Acta Biomaterialia.2005,1,575-582 has invented a kind of preparation single shaft electrostatic filature blood vessel support fiber process, and this method makes the electrostatic filature blood vessel support of the hollow of diameter 6mm.
But, the orientation gathering-device of said structure, can only obtain the thicker electrostatic filature blood vessel support fiber of aperture ratio, the electrostatic filature blood vessel support fiber exists fiber problem pockety simultaneously, make that distribution density and mass preparation process are not fine, need further optimize.
Summary of the invention
The object of the present invention is to provide a kind of parallel type electrostatic filature blood vessel support collector, to overcome the above-mentioned defective that prior art exists.
In order to achieve the above object, solution of the present invention is: this device comprises motor, frame, HV generator, shower nozzle, scale oscillometer, capillary tube cylinder catcher etc.The sun level of HV generator is connected with shower nozzle, and cathode connects catcher; The solution flow rate control device is fixed on the frame, and its solution tank is connected with the scale oscillometer; The solution flow rate control device links to each other with solution tank, and solution conduit one end that is positioned on the solution flow rate control device inserts solution tank, and is connected with shower nozzle.Catcher adopts capillary tube cylinder catcher.
The electrostatic spinning orientation that the present invention proposes is regulated gathering-device, comprises solution flow rate control device, solution conduit, solution tank, shower nozzle, scale oscillometer, frame, motor, also comprise capillary tube cylinder catcher;
Described motor is fixed on the frame, and the outfan of the turning cylinder of motor connects capillary tube cylinder catcher;
Described scale oscillometer is connected with the solution flow rate control device;
Described solution flow rate control device links to each other with solution tank, and solution conduit one end that is positioned on the solution flow rate control device inserts solution tank, and is connected with shower nozzle.
Further, the capillary tube in the described cylinder catcher is and column distribution, and is detachable, rotatable.
Described capillary tube, the fixed form at its two ends are to fix by the draw-in groove on the cylindrical roller panel of capillary tube cylinder catcher, and draw-in groove aperture adjustment scope is 2～5mm.
The cylindrical roller panel of described capillary tube cylinder catcher, wherein, the draw-in groove hole number on the cylindrical roller panel can be regulated, and quantity is 6～15.
Described capillary tube cylinder catcher can inner spinning, makes that the capillaceous original and column distribution on the cylindrical roller panel rearranges.
Parallel type electrostatic filature blood vessel support collector of the present invention, when the preparation electrostatic filature blood vessel support, can control the thickness range of electrostatic filature blood vessel support by the radius of clean-up of regulation and control slip shower nozzle, inside spinning by capillary tube cylinder catcher and the adjusting of draw-in groove pore diameter range make the electrostatic filature blood vessel support in different apertures, and pore diameter range is 2～5mm.
Description of drawings
Fig. 1 is an embodiment of the invention parallel type electrostatic filature blood vessel support collector structural representation.
Fig. 2 is an embodiment of the invention capillary tube cylinder collector structure sketch map.
Fig. 3 is the enlarged diagram of embodiment of the invention capillary tube cylinder catcher draw-in groove structure.
Number in the figure: 1 is the solution flow rate control device, and 2 is solution conduit, and 3 is solution tank, and 4 is shower nozzle, and 5 is the scale oscillometer, and 6 is frame, and 7 is capillary tube cylinder catcher, and 8 is motor, and 9 is capillary tube cylinder catcher draw-in groove, and 10 is card structure 10 in the spring.
The specific embodiment
Below by embodiment the present invention is further illustrated the invention.
Embodiment 1: as seen from Figure 1, this device comprises: solution flow rate control device 1, solution conduit 2, solution tank 3, shower nozzle 4, scale oscillometer 5, frame 6, capillary tube cylinder catcher 7, motor 8.
Described motor 8 is fixed on the frame 6, and the outfan of the turning cylinder of motor connects capillary tube cylinder catcher 7, makes the capillary tube cylinder catcher 7 can inner spinning;
Described scale oscillometer 5 is connected with solution flow rate control device 1;
Described solution flow rate control device 1 links to each other with solution tank 3, and solution conduit 2 one ends that are positioned on the solution flow rate control device 1 insert solution tank 3, and are connected with shower nozzle 4.
Referring to Fig. 1 and Fig. 2, described capillary tube cylinder catcher 7, capillary tube wherein are and column distribution; Two ends capillaceous are fixed by the draw-in groove on the cylindrical roller panel of capillary tube cylinder catcher, and draw-in groove aperture adjustment scope is 2～5mm.
Draw-in groove hole number on the cylindrical roller panel can be regulated, and quantity is 6～15.
Referring to Fig. 1, described scale slip instrument 5 and solution flow rate control device 1 are to be slidingly connected, and a connecting rod one end stretches in the groove on the scale slip instrument 5, and the other end connects solution flow rate control device 1, forms continuous action relation, sliding scale 0～30cm by connecting rod; It can drive spinning nozzle 4 in running.
Referring to Fig. 2 and Fig. 3, described capillary tube cylinder catcher 7 can inner spinning, what capillary tube cylinder catcher draw-in groove 9 adopted is card structure 10 in the spring, can stir card structure 10 in the spring and make the capillaceous original and column distribution on the cylindrical roller panel rearrange in collection process, it can be so that wall energy intactly receives spinning material outside capillaceous in running.
The above-mentioned description to embodiment is can understand and apply the invention for ease of those skilled in the art.The person skilled in the art obviously can easily make various modifications to these embodiment, and needn't pass through performing creative labour being applied in the General Principle of this explanation among other embodiment.Therefore, the invention is not restricted to the embodiment here, those skilled in the art should be within protection scope of the present invention for improvement and modification that the present invention makes according to announcement of the present invention.
Claims (6)
1. electrostatic filature blood vessel support collector, comprise: solution flow rate control device (1), solution conduit (2), solution tank (3), shower nozzle (4), scale oscillometer (5), frame (6), motor (8), it is characterized in that: also comprise capillary tube cylinder catcher (7)
Described motor (8) is fixed on the frame (6), and the outfan of the turning cylinder of motor connects capillary tube cylinder catcher (7);
Described scale oscillometer (5) is connected with solution flow rate control device (1);
Described solution flow rate control device (1) links to each other with solution tank (3), and solution conduit (2) one ends that are positioned on the solution flow rate control device (1) insert solution tank (3), and are connected with shower nozzle (4).
2. electrostatic filature blood vessel support collector according to claim 1 is characterized in that: the capillary tube in the described capillary tube cylinder catcher is and column distribution.
3. electrostatic filature blood vessel support collector according to claim 2 is characterized in that: described two ends capillaceous are fixed by the draw-in groove on the cylindrical roller panel of capillary tube cylinder catcher.
4. electrostatic filature blood vessel support collector according to claim 3 is characterized in that: the range of accommodation in the aperture of described draw-in groove is 2～5mm.
5. electrostatic filature blood vessel support collector according to claim 3 is characterized in that: the draw-in groove quantity on the cylindrical roller panel of described capillary tube cylinder catcher is 6～15.
6. electrostatic filature blood vessel support collector according to claim 3, it is characterized in that: the draw-in groove (9) on the cylindrical roller panel of described capillary tube cylinder catcher is a card structure (10) in the spring, can stir in collection process that card structure makes the capillary tube on the cylindrical roller panel rearrange in the spring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008102043491A CN101474105B (en) | 2008-12-10 | 2008-12-10 | Parallel type electrostatic filature blood vessel support collector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008102043491A CN101474105B (en) | 2008-12-10 | 2008-12-10 | Parallel type electrostatic filature blood vessel support collector |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101474105A CN101474105A (en) | 2009-07-08 |
| CN101474105B true CN101474105B (en) | 2011-05-25 |
Family
ID=40834955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008102043491A Expired - Fee Related CN101474105B (en) | 2008-12-10 | 2008-12-10 | Parallel type electrostatic filature blood vessel support collector |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101474105B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103334168A (en) * | 2013-07-24 | 2013-10-02 | 苏州大学 | Receiving device of electrostatic spinning |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101884573B (en) * | 2010-05-27 | 2012-05-02 | 清华大学 | Multi-nozzle injection device for complex organ prosoma three-dimensional controlled forming machine |
| CN102284404A (en) * | 2010-06-18 | 2011-12-21 | 北京承峰纳泰科技有限公司 | Preparation method of tubular membrane for membrane distillation |
| CZ303380B6 (en) * | 2011-06-27 | 2012-08-22 | Contipro Biotech S.R.O. | Process for producing materials exhibiting anisotropic properties and composed of nanofibers or microfibers and apparatus for making the same |
| CN103225174A (en) * | 2013-04-25 | 2013-07-31 | 北京化工大学 | Method for coating esophageal stent through melt electrospinning |
| CN104141174B (en) * | 2014-07-23 | 2016-06-01 | 北京化工大学 | A kind of electrostatic spinning orientation fibers preparation facilities |
| CN104611773B (en) * | 2015-01-19 | 2017-01-04 | 上海理工大学 | A kind of decentralized casing spinneret arranged side by side and application thereof |
| TWI598479B (en) * | 2015-05-29 | 2017-09-11 | 國立交通大學 | An electrospinning apparatus |
| CN105664262B (en) * | 2016-01-16 | 2019-01-11 | 上海大学 | The method that drum-type collects the three-dimensional perforation class blood vessel structure network bracket of preparation |
| CN106176000B (en) * | 2016-08-31 | 2018-03-23 | 杭州捷诺飞生物科技有限公司 | For preparing the 3D printing device and equipment of angiocarpy bracket |
| CN107201557B (en) * | 2017-05-04 | 2019-09-24 | 郑州大学 | The reception device of electrostatic spinning engineering blood vessel with nonlinear mechanics performance |
| CN108642719B (en) * | 2018-05-11 | 2020-12-01 | 西安工程大学 | Preparation method of integrated small-caliber artificial blood vessel stent |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0009941A1 (en) * | 1978-10-10 | 1980-04-16 | Imperial Chemical Industries Plc | Production of electrostatically spun products |
| WO2002040242A1 (en) * | 2000-11-17 | 2002-05-23 | Virginia Commonwealth University Intellectual Property Foundation | Electroprocessed collagen |
| WO2003087443A1 (en) * | 2002-04-11 | 2003-10-23 | Secant Medical, Inc. | Covering process using electrospinning of very small fibers |
| CN1715463A (en) * | 2004-06-30 | 2006-01-04 | 东华大学 | Static spinning device and its industrial use |
| WO2006036130A1 (en) * | 2004-09-29 | 2006-04-06 | National University Of Singapore | A composite, method of producing the composite and uses of the same |
| CN2915892Y (en) * | 2006-07-10 | 2007-06-27 | 东华大学 | Special collection device for electrostatic spinning |
| WO2007112446A2 (en) * | 2006-03-28 | 2007-10-04 | University Of Washington | Alginate-based nanofibers and related scaffolds |
| WO2008041183A2 (en) * | 2006-10-05 | 2008-04-10 | Technion Research & Development Foundation Ltd. | Microtubes and methods of producing same |
| CN201141055Y (en) * | 2007-11-23 | 2008-10-29 | 东华大学 | Electrostatic spinning device for nano-fiber |
-
2008
- 2008-12-10 CN CN2008102043491A patent/CN101474105B/en not_active Expired - Fee Related
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0009941A1 (en) * | 1978-10-10 | 1980-04-16 | Imperial Chemical Industries Plc | Production of electrostatically spun products |
| WO2002040242A1 (en) * | 2000-11-17 | 2002-05-23 | Virginia Commonwealth University Intellectual Property Foundation | Electroprocessed collagen |
| WO2003087443A1 (en) * | 2002-04-11 | 2003-10-23 | Secant Medical, Inc. | Covering process using electrospinning of very small fibers |
| CN1715463A (en) * | 2004-06-30 | 2006-01-04 | 东华大学 | Static spinning device and its industrial use |
| WO2006036130A1 (en) * | 2004-09-29 | 2006-04-06 | National University Of Singapore | A composite, method of producing the composite and uses of the same |
| WO2007112446A2 (en) * | 2006-03-28 | 2007-10-04 | University Of Washington | Alginate-based nanofibers and related scaffolds |
| CN2915892Y (en) * | 2006-07-10 | 2007-06-27 | 东华大学 | Special collection device for electrostatic spinning |
| WO2008041183A2 (en) * | 2006-10-05 | 2008-04-10 | Technion Research & Development Foundation Ltd. | Microtubes and methods of producing same |
| CN201141055Y (en) * | 2007-11-23 | 2008-10-29 | 东华大学 | Electrostatic spinning device for nano-fiber |
Non-Patent Citations (2)
| Title |
|---|
| C.M. Vaz, S. van Tuijl, C.V.C. Bouten, F.P.T. Baaijens.Design of scaffolds for blood vessel tissue engineering using a multi-layering electrospinning technique.《Acta Biomaterialia》.2005,第1卷(第5期),575-582. * |
| Takehisa Matsuda, Il Keun Kwon, and Satoru Kidoaki.Photocurable Biodegradable Liquid Copolymers: Synthesis of Acrylate-End-Capped Trimethylene Carbonate-Based Prepolymers, Photocuring, and Hydrolysis.《Biomacromolecules》.2004,第5卷(第2期),295-305. * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103334168A (en) * | 2013-07-24 | 2013-10-02 | 苏州大学 | Receiving device of electrostatic spinning |
| CN103334168B (en) * | 2013-07-24 | 2016-01-20 | 苏州大学 | A kind of receiving system of electrostatic spinning |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101474105A (en) | 2009-07-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101474105B (en) | Parallel type electrostatic filature blood vessel support collector | |
| CN103572388B (en) | A kind of needle-free coaxial electrostatic spinning silk device and spinning process | |
| CN201284386Y (en) | Electrostatic spun orientation regulating collecting device | |
| CN105839204B (en) | Layering intravascular stent formation system and method based on electrostatic direct write and electrostatic spinning technique | |
| CN201053041Y (en) | Electrostatic spinning device | |
| CN101586288A (en) | Array multi-nozzle electrospinning device | |
| CN202090111U (en) | Near field electrostatic spinning device for continuous liquid supply | |
| CN108159976A (en) | A kind of Water-In-Oil Bao Shui（W/W/O）Monodisperse double emulsion preparation method and its micro fluidic device | |
| CN103820943A (en) | Macropore three-dimensional ordered-orientation silk fibroin nano-fiber support and preparation method thereof | |
| EP2743390A1 (en) | Method and device for production of nanofibrous textile, mainly for seeding living organisms | |
| CN108691225A (en) | A kind of wellability composite twist towline and preparation method thereof of efficient collection mist | |
| CN210262218U (en) | Weaving machine of removable different diameter crochet hooks | |
| CN102061529B (en) | Spraying nozzle device for electrostatic spinning | |
| CN101423984A (en) | Ice surface collection method of polymer fiber electrostatic imitated silk and apparatus thereof | |
| WO2009044492A1 (en) | Method of removing sizing agent, and yarn, fiber body and prepreg | |
| CN2915892Y (en) | Special collection device for electrostatic spinning | |
| CN105671657A (en) | Small-aperture artificial blood vessel preparation device based on electrostatic spinning | |
| CN207756001U (en) | A kind of hollow fiber film yarn beam | |
| CN102492999B (en) | Spray nozzle capable of realizing mass production of nanometer fibers in electrostatic spinning method | |
| CN208429898U (en) | A kind of photocatalysis membrana unit for purification of water quality | |
| CN219942406U (en) | Glass fiber reinforced plastic butterfly pipe type reverse osmosis membrane shell with improved structure | |
| CN209412534U (en) | A kind of textile material tanning device facilitating adjusting | |
| CN103952777A (en) | Novel multifunctional nanofiber electrostatic spinning machine | |
| CN203319757U (en) | Aerating apparatus of flat membrane bioreactor | |
| CN218067229U (en) | Water source collection device for sewage detection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110525 Termination date: 20171210 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |