CN101446454A - Refrigeration method for freezedryers to backup each other - Google Patents
Refrigeration method for freezedryers to backup each other Download PDFInfo
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- CN101446454A CN101446454A CNA2008102072935A CN200810207293A CN101446454A CN 101446454 A CN101446454 A CN 101446454A CN A2008102072935 A CNA2008102072935 A CN A2008102072935A CN 200810207293 A CN200810207293 A CN 200810207293A CN 101446454 A CN101446454 A CN 101446454A
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- compressor
- freeze dryer
- shelf
- freeze
- freezedryer
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Abstract
The invention relates to a refrigeration method for freezedryers to backup each other. The method is characterized in that a first compressor and a second compressor are connected with a first freezedryer respectively by board connection to refrigerate the shelf of the first freezedryer; at the same time, the first compressor or the second compressor is connected with a second freezedryer by the board connection to refrigerate the shelf of the second freezedryer; a third compressor and a fourth compressor are connected with the second freezedryer respectively by the board connection to refrigerate the shelf of the second freezedryer; and at the same time, the third compressor or the fourth compressor is connected with the first freezedryer by the board connection to refrigerate the shelf of the first freezedryer. The invention has the advantages of being capable of realizing the very fast speed for refrigerating the shelf of the freezedryer and improving the reliability and the stability of the system greatly.
Description
Technical field
The present invention relates to the mutually redundant refrigerating method of a kind of freeze dryer, but the hydrous matter of freeze-drying or solution are freezed in advance at low temperatures, under vacuum environment, make the material dehydration obtain dry article then, belong to the vacuum freeze drier technical field.
Background technology
Vacuum freeze drying (abbreviation freeze dryer) but be exactly that the hydrous matter of freeze-drying or solution are freezed in advance at low temperatures, under vacuum environment, make the material dehydration obtain dry article then.
This drying means with common dry, dry, boil dry, spray-drying is compared with vacuum drying that many outstanding advantages are arranged:
(1) do not make protein, microorganism and so on produce sex change or lose biologos;
(2) loss of the nutritional labeling of volatile ingredient in the material and heated denaturalization is little;
(3) effect of microbial growth and enzyme almost can't be carried out, and can keep the original proterties of material best;
(4) drying back form is constant substantially, is spongy open structure; Rehydration is easy, can promptly be reduced into former
The proterties of coming;
(5) dry under vacuum, oxygen is few, makes the material of easy oxidation obtain protection;
(6) can remove in the material 95%～99% moisture, the goods long shelf-life;
So freeze dryer is widely used in: pharmaceuticals industry, biological products; Biological tissue, microbiology class; Animals and plants; Food industry; Chemical industry; Health care products and Chinese herbal medicine etc.
Freeze dryer mainly comprises refrigeration system, vacuum system, the circulatory system, hydropneumatic system, CIP/SIP system, control system etc., wherein refrigeration system is the core of freeze dryer, it is the cardia of freeze dryer, so the quality of refrigeration system quality directly has influence on the reliable type of freeze dryer system operation, what the tradition freeze dryer adopted is the refrigeration modes of piston machine or screw rod machine, and shortcoming is: refrigerating speed is slow comparatively speaking; The refrigeration system backup capabilities is strong inadequately.In existing medicine freeze-drier, the freezing process of medicine is finished mostly on the shelf, and the rate of temperature fall of shelf is relatively slow, is generally less than 2 ℃/min.Liquid formulation is with in the shelf temperature-fall period, ice crystal forms prior to the cillin bottle bottom, and thermograde is relatively large in the upper heat and lower cold, preparation, ice interface degree of pushing ahead is slow, solute migration time abundance in the solution, solution surface frozen crust solute gathers more, and high concentration " top layer duricrust " phenomenon occurs easily, form one deck fine and close " duricrust " behind the high concentration superficial drying, thereby the effusion of water vapour in the obstruction freeze-drying process prolongs freeze-drying time, increases the difficulty of freeze-dried products rehydration.In the actual production process, the solute Distribution inequality that the shelf slow freezing forms also can cause the difference of residual water content after the medicine preparation drying, and this solute and water content problem of uneven distribution thereof can be brought adverse influence to the storage-stable of freeze-drying process and product.
Summary of the invention
The purpose of this invention is to provide the mutually redundant refrigerating method of the fast freeze dryer of a kind of refrigerating speed.
For realizing above purpose, technical scheme of the present invention provides the mutually redundant refrigerating method of a kind of freeze dryer, it is characterized in that, first compressor is handed over by plate with second compressor and is connected with first freeze dryer respectively, shelf to first freeze dryer freezes, first compressor or second compressor give second freeze dryer to connect by plate simultaneously, shelf to second freeze dryer freezes, the 3rd compressor is handed over by plate with the 4th compressor and is connected with second freeze dryer respectively, shelf to second freeze dryer freezes, simultaneously the 3rd compressor or the 4th compressor give first freeze dryer to connect by plate, and the shelf of first freeze dryer is freezed.
Refrigeration system between two freeze dryers of the present invention can be done mutual backup, but also can realize the purpose of freeze dryer fast-refrigerating, first freeze dryer is provided with two compressors, wherein there is a compressor can the shelf of second freeze dryer be freezed, second freeze dryer is provided with two compressors equally, wherein there is a compressor can the shelf of freeze dryer be freezed, that is to say no matter be that first freeze dryer or second freeze dryer can realize that all 3 compressors freeze to it, but two total freeze dryers only are equipped with 4 compressors, and Pei Zhi benefit is like this:
1. can realize the refrigeration speed that the freeze dryer shelf is very fast, freezing dry process is complicated heat transfer, mass transport process, freeze-drying process and freezing process are closely related, the latter has determined the time of freeze-drying process and the quality of dried frozen aquatic products to a certain extent, accelerated the pre-freeze speed of goods greatly, played very large effect for the raising of quality of item.
2. the compressor between two freeze dryers can be realized backuping each other, even if there is a compressor to break down in the freeze-drying process, can opens the refrigeration compressor of an other freeze dryer immediately and support, and improves the reliability and stability of system greatly.
Description of drawings
Fig. 1 is the mutually redundant refrigerating method schematic diagram of a kind of freeze dryer.
The specific embodiment
The invention will be further described below in conjunction with drawings and Examples.
Embodiment
As shown in Figure 1, be the mutually redundant freeze dryer structural representation of a kind of refrigeration system, the mutually redundant freeze dryer of described a kind of refrigeration system is made up of first freeze dryer 1, first compressor 2, second compressor 3, second freeze dryer 4, the 3rd compressor 5 and the 4th compressor 6.
The mutually redundant refrigerating method of a kind of freeze dryer is: first compressor 2 is handed over by plate with second compressor 3 and is connected with first freeze dryer 1 respectively, shelf to first freeze dryer 1 freezes, second compressor 3 gives second freeze dryer 4 to connect by plate simultaneously, shelf to second freeze dryer 4 freezes, the 3rd compressor 5 is handed over by plate with the 4th compressor 6 and is connected with second freeze dryer 4 respectively, shelf to second freeze dryer 4 freezes, the 3rd compressor 5 gives first freeze dryer 1 to connect by plate simultaneously, shelf to first freeze dryer 1 freezes, and improves refrigerating speed.
Claims (1)
1. mutually redundant refrigerating method of freeze dryer, it is characterized in that, first compressor (2) is handed over by plate with second compressor (3) and is connected with first freeze dryer (1) respectively, shelf to first freeze dryer (1) freezes, first compressor (2) or second compressor (3) give second freeze dryer (4) to connect by plate simultaneously, shelf to second freeze dryer (4) freezes, the 3rd compressor (5) is handed over by plate with the 4th compressor (6) and is connected with second freeze dryer (4) respectively, shelf to second freeze dryer (4) freezes, simultaneously the 3rd compressor (5) or the 4th compressor (6) give first freeze dryer (1) to connect by plate, and the shelf of first freeze dryer (1) is freezed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810207293 CN101446454B (en) | 2008-12-18 | 2008-12-18 | Refrigeration method for freezedryers to backup each other |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810207293 CN101446454B (en) | 2008-12-18 | 2008-12-18 | Refrigeration method for freezedryers to backup each other |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101446454A true CN101446454A (en) | 2009-06-03 |
| CN101446454B CN101446454B (en) | 2010-12-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200810207293 Expired - Fee Related CN101446454B (en) | 2008-12-18 | 2008-12-18 | Refrigeration method for freezedryers to backup each other |
Country Status (1)
| Country | Link |
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| CN (1) | CN101446454B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028623A (en) * | 2010-12-28 | 2011-04-27 | 昆明龙津药业股份有限公司 | Continuous production process for freeze-dried preparation |
| CN106440479A (en) * | 2016-12-12 | 2017-02-22 | 远大空调有限公司 | High-efficiency condensation heat recovery heating device and method |
-
2008
- 2008-12-18 CN CN 200810207293 patent/CN101446454B/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028623A (en) * | 2010-12-28 | 2011-04-27 | 昆明龙津药业股份有限公司 | Continuous production process for freeze-dried preparation |
| CN106440479A (en) * | 2016-12-12 | 2017-02-22 | 远大空调有限公司 | High-efficiency condensation heat recovery heating device and method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101446454B (en) | 2010-12-01 |
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Granted publication date: 20101201 Termination date: 20191218 |
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| CF01 | Termination of patent right due to non-payment of annual fee |