CN101432266A - 双环四氢吡咯化合物的制备方法 - Google Patents

双环四氢吡咯化合物的制备方法 Download PDF

Info

Publication number
CN101432266A
CN101432266A CNA2007800151584A CN200780015158A CN101432266A CN 101432266 A CN101432266 A CN 101432266A CN A2007800151584 A CNA2007800151584 A CN A2007800151584A CN 200780015158 A CN200780015158 A CN 200780015158A CN 101432266 A CN101432266 A CN 101432266A
Authority
CN
China
Prior art keywords
group
optional
alkyl
saturated
unsaturated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800151584A
Other languages
English (en)
Chinese (zh)
Inventor
M·A·佩里卡斯-布朗多
A·托伦斯-约弗
S·耶尼斯-明古茨
F·库瓦斯科多贝斯
C·加西亚格兰达
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of CN101432266A publication Critical patent/CN101432266A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
CNA2007800151584A 2006-04-28 2007-04-30 双环四氢吡咯化合物的制备方法 Pending CN101432266A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06008887A EP1849770A1 (en) 2006-04-28 2006-04-28 Production process for bicyclic tetrahydropyrrole compounds
EP06008887.9 2006-04-28

Publications (1)

Publication Number Publication Date
CN101432266A true CN101432266A (zh) 2009-05-13

Family

ID=37102943

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800151584A Pending CN101432266A (zh) 2006-04-28 2007-04-30 双环四氢吡咯化合物的制备方法

Country Status (7)

Country Link
US (1) US20090306403A1 (https=)
EP (2) EP1849770A1 (https=)
JP (1) JP2009535314A (https=)
CN (1) CN101432266A (https=)
CA (1) CA2641405A1 (https=)
MX (1) MX2008013476A (https=)
WO (1) WO2007128457A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1849772A1 (en) * 2006-04-28 2007-10-31 Laboratorios Del Dr. Esteve, S.A. Bicyclic tetrahydropyrrole compounds
EP2029536B1 (en) * 2006-04-28 2013-08-28 Laboratorios Del. Dr. Esteve, S.A. Bicyclic tetrahydropyrrole compounds
JP2010150211A (ja) * 2008-12-26 2010-07-08 Toray Fine Chemicals Co Ltd １−アラルキル−３−ピロリン化合物の製造法
EP3789377A1 (en) * 2019-09-03 2021-03-10 Fundación Universitaria San Pablo-Ceu A catalytically continuous flow pauson-khand reaction without carbon monoxide gas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5359087A (en) * 1993-06-03 1994-10-25 Regents Of The University Of Minnesota Bioactive quisqualic acid analogs
US5491241A (en) * 1993-10-18 1996-02-13 Eli Lilly And Company Bicyclic intermediates for excitatory amino acid receptor antagonists
US6384050B1 (en) * 1996-10-25 2002-05-07 Daiichi Pharmaceutical Co., Ltd. Tricyclic amine derivatives
GB0218260D0 (en) * 2002-08-06 2002-09-11 Charterhouse Therapeutics Ltd Improvements in pharmaceutically useful compounds
US20040044029A1 (en) * 2002-08-14 2004-03-04 Dart Michael J. Azabicyclic compounds are central nervous system active agents
EP1849772A1 (en) * 2006-04-28 2007-10-31 Laboratorios Del Dr. Esteve, S.A. Bicyclic tetrahydropyrrole compounds
EP2029536B1 (en) * 2006-04-28 2013-08-28 Laboratorios Del. Dr. Esteve, S.A. Bicyclic tetrahydropyrrole compounds

Also Published As

Publication number Publication date
US20090306403A1 (en) 2009-12-10
CA2641405A1 (en) 2007-11-15
JP2009535314A (ja) 2009-10-01
WO2007128457A1 (en) 2007-11-15
MX2008013476A (es) 2008-10-29
EP1849770A1 (en) 2007-10-31
EP2076493A1 (en) 2009-07-08

Similar Documents

Publication Publication Date Title
EP1829869A1 (en) 4,5,6,7-Tetrahydrobenzo[b]thiophene derivatives and their use as sigma receptor ligands
JP2009534344A (ja) シグマ（σ）受容体を阻害するスピロ［ベンゾピラン］誘導体またはスピロ［ベンゾフラン］誘導体
US9271959B2 (en) Bicyclic tetrahydropyrrole compounds
EP1718619A1 (en) Substituted pyrazoline compounds for reducing triglycerides in blood
JP6370803B2 (ja) シグマ受容体関連疾病及び障害の治療のための１，２，３−トリアゾール−４−アミン誘導体
CN101432266A (zh) 双环四氢吡咯化合物的制备方法
EP2029536B1 (en) Bicyclic tetrahydropyrrole compounds
EP1996548B1 (en) Sigma receptor compounds
EP1849771A1 (en) Bicyclic tetrahydropyrrole compounds
HK1216641B (en) 1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20090513