CN101426540A - Device and systems for the intermittent drainage of urine and other biological fluids - Google Patents

Device and systems for the intermittent drainage of urine and other biological fluids Download PDF

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Publication number
CN101426540A
CN101426540A CNA2005800177975A CN200580017797A CN101426540A CN 101426540 A CN101426540 A CN 101426540A CN A2005800177975 A CNA2005800177975 A CN A2005800177975A CN 200580017797 A CN200580017797 A CN 200580017797A CN 101426540 A CN101426540 A CN 101426540A
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China
Prior art keywords
negative pressure
eduction gear
conduit
pump
gathering
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Pending
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CNA2005800177975A
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Chinese (zh)
Inventor
M·L·斯托勒
M·V·蒙
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University of California
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University of California
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Abstract

This invention provides a drainage device for biological fluids. The device typically comprises a port for attachment of the device to a catheter or to a waste collection device; and a means for applying a negative pressure to said port, wherein said negative pressure is an intermittent substantially constant negative pressure.

Description

The eduction gear and system at intermittence of urine and other biological fluid
The reference of related application
The United States Patent (USP) serial number that the application requires on May 27th, 2004 to propose is that the United States Patent (USP) serial number of proposition on April 2nd, 60/575,468 and 2004 is 60/559,179 rights and interests and priority, and both are introduced in full as general reference.
Technical field
The present invention relates to use the gathering-device and the method for urine and other biological fluid conduit.
Background technology
The urine conduit, for example the Foley conduit is hollow, the tube that is generally used for medical profession, is used for inserting by urethra tube patient's bladder, and the urine conductance is gone out.Using catheter is necessary to the patient who suffers surgical diseases, plastic surgery's disease, incontinence or can not arbitrarily urinate usually.Yet the unfavorable problem of catheterization is that the development that sepsis and/or urethra tube infect (UTIs) causes antibacterial to invade bladder and urethra tube by various microorganisms.Sepsis is a kind of potential fatal factor, and the most common in the old people, and wherein urethra tube and bladder infection become and be very easy to influence whole body, particularly under the insufficient situation of hydration of hygienic knowledge shortage and tissue.The danger of sepsis increases with the use of urine conduit, wherein common plant and/or upwards enter bladder easily from the antibacterial of feces or skin around the conduit that inserts.
In addition, the residual urine that keeps staying cool around the air bag provides a kind of culture medium under warm body temperature, and it promotes the growth of antibacterial.As a result, antibacterial can accumulate in bladder, breed and cause a disease, and final circulation flows into kidney and whole body system, causes the sepsis of body system.Be used for this tendency that infects in patient's generation, although conduit is useful, medical practitioner usually refuses to expand its use.
Summary of the invention
The invention provides a kind of eduction gear of biological fluid.This device typically comprises the path of device fitting to conduit or rubbish collecting device; And applying means for applying negative to described path, wherein said negative pressure is intermittently and substantially invariable negative pressure.
Definition
Term " intermittently ", when with respect to " intermittently and substantially invariable negative pressure ", this term refers to be used for the negative pressure that then stops at interval.
Term " substantially constant ", when using this system with respect to substantially invariable negative pressure, this term has referred to change no more than about 20% negative pressure, is preferably no more thanly about 10% or 15%, and best is no more than about 5%.
Term " closed system " refers to the system that can be handled by user, and not have to contact the danger of the biological fluid that is present in this system substantially.
Any one that the term biological fluid refers to be produced by biologic artifact or multiple liquid.This biofluid includes but not limited to urine, seminal fluid, brains liquid, blood or clot, plasma, saliva or other mouthful liquid, gastric juice, bile, pus, liquefaction tissue or the like.
Term " conduit " is used in reference to any excretory duct here, is used for the collection of body fluid.This device includes but not limited to the Foley conduit, any other conduit, nasal feeding tube, Jackson Pratt Drain or spherical draining (bulb drain) or the like.
Description of drawings
Fig. 1 schematically shows eduction gear 2, and this eduction gear 2 comprises the interior arrangement 6 that produces negative pressure.
Fig. 2 schematically shows eduction gear 2, and this eduction gear 2 together uses with external vacuum source 22.
Fig. 3 schematically shows eduction gear 2, and this eduction gear 2 comprises the crank 20 that produces the energy that is used for manipulation device 6, and manipulation device 6 is used to produce negative pressure.
Fig. 4 represents an example according to " linear configurations " of drainage/gathering system of the present invention.
Fig. 5 represents an example according to " the T-configuration " of drainage/gathering system of the present invention.
The specific embodiment
The present invention relates to surprising discovery in most of typical patients, the remarkable free-pouring Foley conduit of liquid is inserted in its body, urine (for example 200-400ml) remains in the bladder substantially.The placement pond of this urine (standing pool) has increased the probability of infection (for example sepsis and/or UTIs) and has reduced the drainage of kidney.
Surprising discovery is, lower negative pressure (absorption) is put on conduit and/or conduit to excretory container wherein, particularly intermittently (for example at random, accidental or the cycle) negative pressure has been eliminated the residual pond of urine effectively, has reduced the outbreak of infecting, and has promoted the health of bladder and kidney.In certain preferred embodiment, in application, intermittently negative pressure is substantially invariable negative pressure (for example the change of negative pressure amplitude is less than about 20% or 25%).
Be not limited to particular principles, certainly intermittently negative pressure has been eliminated " vent plug " in conduit and the relevant refuse/ejection system.What can also affirm is that negative pressure has overcome surface tension effects, thereby stops flow of liquid to cross conduit and/or refuse/ejection system.In addition, certainly intermittently negative pressure has strengthened " siphon " effect in the conduit, thereby has strengthened the discharge function of bladder.
In addition, also have surprising discovery to be, the intermittence of negative pressure is more effective than constant negative pressure in this.Be not limited to particular principles, certainly when bladder was fully drained, constant negative pressure caused the conduit obturation because of mucosa (for example mucosa of arranging along bladder).Intermittently negative pressure has reduced or eliminated this obturation, has also reduced the stimulation to mucosa.
Simultaneously, in certain embodiment, system of the present invention is particularly suitable for promoting the drainage of bladder, and certainly this method and apparatus also is suitable for draining other biological fluid (for example nasal feeding body fluid, peritoneum body fluid, particularly the conduit at position flows out outside inserting barrier film, or the like).Therefore, when reference example such as Foley conduit show device described herein and system, be appreciated that they can be used for any biological fluid gathering-device in fact similarly.This device includes but not limited to nasal feeding tube, Jackson Pratt Drain or spherical draining or the like.
Therefore, in certain embodiment, the invention provides a kind of biological fluid eduction gear.Fig. 1 has schematically shown a this device.Device 2 typically comprises path 4, is used for this device is connected in collecting pipe 18, conduit or rubbish collecting device; And install 6, be used for negative pressure is put on this path.In the embodiment shown in fig. 1, being used to apply means for applying negative is membrane pump 6.This pump is connected in actuator 10 by electric wire 28b, and controller 14 is provided in certain preferred embodiment, is used to adjust the time of opening and/or closing of pump, and/or controller 16 is provided, and is used to adjust the negative pressure amplitude.Actuator and pump are by power supply 8 (permanent battery for example, removable battery, manual generator, the battery/generator combination or the like) excitation that for example is connected in actuator by electric wire 28a.Negative pressure typically intermittently and substantially invariable negative pressure.When Fig. 1 represented membrane pump, the multiple device that is used to apply negative pressure was known for a person skilled in the art, and was suitable for using in this device.In described embodiment, membrane pump 6 is discharged gas by path 12.
In certain embodiment, be used to apply means for applying negative 6 and comprise pneumatic, motor-driven or electronic vacuum pump.Suitable vacuum pump includes but not limited to piston pump, centrifugal pump, bellows pump, membrane pump or the like.
Device of the present invention is not limited to the use of various vacuum pumps.In certain embodiment, this device can be configured to external vacuum source and is connected (for example wall vacuum).In this example, as shown in Figure 2, this device typically comprises path 26 or other adapter (joint, flange, luer locking piece etc.), is used to connect external vacuum source 22.Except pump, this device comprises pressure regulator/valve module 24.This regulator valve assembly is adjusted the amplitude of negative pressure, and make this valve circulation to provide intermittently substantially invariable negative pressure.This regulator valve assembly for example is connected in actuator 10 by electric wire 28b, in certain preferred embodiment, is provided for adjusting the controller of opening and/or close the time 14 of this valve, and/or is used to regulate the controller 16 of negative pressure amplitude.In various embodiments, actuator 10 by shown in electric wire 28a obtain electric energy from power supply 8.
As mentioned above, this device can encourage by electric power, perhaps encourages by manual in certain embodiment.When manual excitation, being used to apply means for applying negative 6 can be manual pump (for example crank driving pump, " compressed ball pump ", syringe etc.) or electrodynamic pump, and wherein electric energy obtains from hand gear (crank 20/ clockwork generator for example shown in Figure 3) basically.If this device by dynamic drive, then can be encouraged by external power source, and/or by internal electric source excitation the battery of permanent installation (for example removable or).Certain embodiment considers the disposable device 2 that comprises integral battery door.This battery can be recharged, or when battery was depleted, whole device 2 was replaced.Certain embodiment considers light stimulus or light rechargeable battery, and wherein this device main body also comprises one or more photoelectric cells, with this pump of direct-drive and/or to encouraging the battery charge of this pump.
This pump or other vacuum source typically are conditioned, draw to provide intermittently, and in the absorption cycle, negative pressure amplitude substantially constant (for example its amplitude of variation is not higher than about 20% or 25%).
In certain preferred embodiment, this device is fully independently (to comprise battery), and can use arbitrarily.This device be easy to be fixed on conduit (or other gathering-device) and/or with waste canister that conduit is connected on, thereby negative pressure is connected in conduit cavity.
In certain embodiment, applying of negative pressure can be at random, accidental or cycle.In certain embodiment, apply between the negative pressure periodic regime from about per 30 seconds by approximately per 4 hours, better from approximately per 1 minute to approximately per 1 or 2 hour, preferably from approximately per 2 minutes to approximately per 30 minutes or 1 hour.The persistent period scope that applies negative pressure typically from about 5 seconds by about 1 hour, preferably from about 10 seconds by about 10 minutes, preferably from about 10 seconds to about 30 seconds.In certain embodiment, negative pressure was applied in 15 seconds kinds at per 10 minutes.
Negative pressure is lower negative pressure, in certain embodiment, from about 40cm water, preferably from about 30cm water, preferably from about 1 or 5cm water up to about 15cm water.
The system shown in bladder drainage various that acts on schematically shows in Fig. 4 and Fig. 5.Should notice that this system can use with any eduction gear basically similarly when Fig. 4 and Fig. 5 represent the Foley conduit.
As shown in Figure 4, eduction gear 2 can be used for bladder 40 is drained.In " linear configurations " shown in Figure 4, gathering-device/conduit 38 (shown in the Foley conduit that comprises air bag 42) is connected in the connection tube 44a that stops in adapter 36.Adapter 36 closely cooperates with another adapter 34, is connected in rubbish collecting device 46, for example drainage bag by connection tube 44b and/or 44c conversely.Rubbish collecting device 46 comprises anti-return trap (trap) alternatively, refluxes by connection tube and/or excretory duct to stop urine (or other biological fluid).Drainage bag further comprises the trap that stops body fluid to flow into eduction gear (pump) 2 alternatively.
When eduction gear 2 was energized, negative pressure was applied in gathering-device 38 (for example Foley conduit) by the collecting bag that links to each other with excretory duct 44a, 44b, and inserted the liquid into rubbish collecting device 46 by gathering-device and excretory duct.When device 2 was closed, liquid continued to flow by siphonage.This system is typically in waste collection container 46 with install on for example waste canister 46 (for example litter bag) between 2 valve is housed, perhaps as the element of device 2.When this valve is opened, allow gas to pass in and out this system, when this valve cuts out, with this system and air insulated.When device 2 when opening, this valve (for example ball valve, disk valve etc.) cuts out, and makes negative pressure at collecting bag and/or form in the various pipes of this system and form, thereby with body fluid sucking-off biological part (for example bladder).When device 2 was closed, this valve was opened so that air can be discharged from this system, thereby makes body fluid flow into collecting bag by waveguide by siphonage.One or more check-valves (for example 48a, 48b) can assemble at all places in this system, reflux by this system to stop body fluid.Check-valves 50 also can stop body fluid inflow device 2.
Fig. 5 schematically shows this system " T-structure ".In this structure, eduction gear 2 is connected between waste canister 46 and the gathering-device/conduit 38 (for example Foley conduit) by " T " or " Y ".In the embodiment shown in fig. 5, " T-" or " Y-" connects by adapter 36 generation effects, makes eduction gear 2 and/or waste canister 46 and this system be easy to be connected or break away from.This system with optional trap 32 shown in Figure 5 stops the body fluid access to plant 2 by this systematic collection.This system comprises check-valves 50 alternatively, and it also can limit body fluid inflow device 2.In various embodiments, one or two of two positions shown in valve 50 is positioned at.Rubbish collecting device 46 comprises the anti-return trap alternatively, and it stops urine (or other biological fluid) to reflux by connection tube and/or excretory duct.In certain embodiment, when installing 52 when this system applies negative pressure, rubbish collecting device 46 comprises check valve 52.When negative pressure was closed, valve 52 was opened, and made waste canister discharge refuse, and body fluid is entered and was full of this container.
In various embodiments, this system typically between litter bag and this device 2 etc., for example is equipped with valve on litter bag.When this valve is opened, make air pass in and out this system, when this valve cuts out, make this system and air insulated.When device 2 when opening, this valve (for example ball valve, disk valve etc.) cuts out, and makes negative pressure at waste canister 46 and/or form in the various pipes of this system and form, thereby with body fluid sucking-off biological part (for example bladder).When device 2 was closed, this valve was opened so that air can be discharged from this system, thereby makes body fluid flow into waste canister by waveguide by siphonage.One or more check-valves (for example 48a, 48b) can assemble at all places in this system, reflux by this system to stop body fluid.
In certain embodiment, the present invention also provides instrument.In various embodiments, this instrument typically comprises eduction gear 2 and the gathering-device (for example conduit or other gathering-device) that puts on specific part described herein.This instrument is typically packaged, so that this gathering-device and/or eduction gear are sterile, perhaps can be placed in traditional disinfector.In certain embodiment, this instrument further comprises connection tube, and/or waste canister, is used to receive the biological fluid of discharging from specific part.This instrument further comprises the instruction material alternatively, and this instruction material indication is used described eduction gear with gathering-device.In various embodiments, this instruction material is the suitable negative pressure of expression further, the persistent period of opening and/or closing of described position (for example lung, oral cavity, thoracic cavity, wound, bladder or the like) being drained employed described eduction gear.
When typically comprising, the instruction material writes or during printing material, they are not limited thereto.The present invention has considered and anyly can store this instruction and make it and the media of communicating with terminal user.This media includes but not limited to electric storage medium (for example disk, tape, cassette tape, chip), light media (for example CD ROM) or the like.This media can comprise the address of the internet site that this instruction material is provided.
Be appreciated that example described herein and embodiment only are for illustrative purposes, those skilled in the art can propose various modifications or the change carried out at it, and are included in the application's the spirit and scope and in the scope of claims.All publications, patent and the patent application of quoting here all is with its whole introducing as general reference.

Claims (45)

1, a kind of eduction gear of biological fluid, described device comprises:
Device fitting is to the path of conduit or rubbish collecting device;
Apply means for applying negative to described path, wherein said negative pressure is intermittence and substantially invariable negative pressure.
2, eduction gear as claimed in claim 1, the described device that wherein is used to apply negative pressure is a manual pump.
3, eduction gear as claimed in claim 1, wherein said pump comprises compressed ball.
4, eduction gear as claimed in claim 1, the described device that wherein is used to apply negative pressure is an electric pump.
5, eduction gear as claimed in claim 4, wherein said electric pump is battery-powered.
6, eduction gear as claimed in claim 4, wherein said device further are included as described electric pump power supply or are the photovoltaic element of battery charge.
7, eduction gear as claimed in claim 4, wherein said electric pump are selected from the group that centrifugal pump, bellows pump, membrane pump and piston pump constitute.
8, eduction gear as claimed in claim 1, wherein said device further comprise the device in the cycle that is used to adjust described negative pressure and/or described negative pressure amplitude.
9, eduction gear as claimed in claim 1, per 30 seconds, extremely about per 30 minutes interval applied negative pressure to wherein said device with approximately.
10, eduction gear as claimed in claim 1, per 30 seconds, extremely about per 10 minutes interval applied negative pressure to wherein said device with approximately.
11, eduction gear as claimed in claim 1 wherein is used to apply the negative pressure of the described device generation of negative pressure until about 100cm water.
12, eduction gear as claimed in claim 1 wherein is used to apply the negative pressure of the described device generation of negative pressure until about 40cm water.
13, eduction gear as claimed in claim 1 wherein is used to apply the negative pressure of the described device generation of negative pressure until about 15cm water.
14, eduction gear as claimed in claim 1, wherein said path are the paths that is additional to Foley conduit or Foley conduit gathering-device.
15, eduction gear as claimed in claim 1, wherein said device is battery-powered, this battery is described device part of the whole, and described device is disposable.
16, eduction gear as claimed in claim 1, wherein said device comprises electric pump, and the electric power of described pump is provided by manual generation system.
17, eduction gear as claimed in claim 16, wherein said manual generation system is a clockwork spring clockwork generator.
18, be used to realize the system of bladder drainage, described system comprises:
Insert the conduit of described bladder;
Eduction gear according to one of claim 1 to 17; And
The rubbish collecting device that links to each other by liquid with described conduit.
19, system as claimed in claim 18, wherein said conduit is the Foley conduit.
20, system as claimed in claim 18, wherein said conduit is a Jackson Pratt pipe.
21, system as claimed in claim 18, wherein said rubbish collecting device is the bedside drainage bag.
22, system as claimed in claim 21, wherein said rubbish collecting device comprises anti-adverse current trap.
23, system as claimed in claim 18, wherein said system further comprise and are used to prevent that liquid return from going into the trap of described eduction gear.
24, system as claimed in claim 23, wherein said trap is the parts of rubbish collecting device.
25, system as claimed in claim 23, wherein said trap be independent maybe can be isolating from described rubbish collecting device.
26, system as claimed in claim 18, wherein said system further comprises one or more check-valves, refluxes by described system to prevent liquid.
27, system as claimed in claim 18, wherein said system further comprises drain valve, this valve makes system cut out with respect to big sky when eduction gear applies negative pressure, and this system is opened with respect to atmosphere and allows air to flow out at liquid.
28, system as claimed in claim 18, wherein said system is a closed system.
29, system as claimed in claim 18, wherein said eduction gear is connected between described conduit and the described rubbish collecting device with the T-structure.
30, system as claimed in claim 18, wherein said eduction gear is connected in described rubbish collecting device with linear configurations.
31, be used for reducing the method that urethra tube infects the person under inspection who suffers from the urethra tube disease, described method comprises:
Will be intermittently and substantially invariable negative pressure put on described conduit, thereby the urine that described negative pressure has reduced in described person under inspection's the bladder keeps, thereby reduced the incidence rate that urethra tube infects.
32, method as claimed in claim 31, the wherein said step that applies comprises the device of utilization according to claim 1 to 17.
33, method as claimed in claim 31 wherein provides described negative pressure by suction means, and this suction means is fixed on described conduit or collecting pipe or the collecting bag.
34, method as claimed in claim 31 wherein provides described negative pressure by suction means, and this suction means is fixed on the waste canister, and this waste canister is fixed on the described conduit.
35, method as claimed in claim 31, wherein said intermittence and substantially invariable negative pressure are applied in about per 30 seconds to about per 10 minutes interval.
36, derive the method for biological fluid from certain position of person under inspection, described method comprises:
Described position described person under inspection provides gathering-device;
To link to each other by liquid with described gathering-device according to the device of one of claim 1 to 17, when being energized with the described device of box lunch, liquid is introduced into waste canister by described gathering-device.
37, method as claimed in claim 36, wherein said gathering-device are selected from the group that Foley conduit, nasal feeding tube and Jackson Pratt pipe constitute.
38, method as claimed in claim 36, wherein said position are selected from the group that lung, oral cavity, thoracic cavity, wound and bladder constitute.
39, a kind of instrument that is used for drawing biological fluid from person under inspection's a certain position, described instrument comprises:
Be applied to the gathering-device at described position; And
Eduction gear according to one of claim 1 to 17.
40, instrument as claimed in claim 39 further comprises the waste canister of the biological fluid that reception is drawn from described position.
41, instrument as claimed in claim 39, wherein said gathering-device is a conduit.
42, instrument as claimed in claim 39, wherein said gathering-device are selected from the group that Foley conduit, Jackson Pratt pipe and nasal feeding tube constitute.
43, instrument as claimed in claim 39, wherein said instrument further comprises the instruction material, this instruction material indication is with the use of the described eduction gear of described gathering-device.
44, instrument as claimed in claim 43, wherein said instruction material be the suitable negative pressure of expression further, the persistent period of opening and/or closing of described position being drained employed described eduction gear.
45, instrument as claimed in claim 39, wherein said position are selected from the group that lung, oral cavity, thoracic cavity, wound and bladder constitute.
CNA2005800177975A 2004-04-02 2005-04-01 Device and systems for the intermittent drainage of urine and other biological fluids Pending CN101426540A (en)

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US55917904P 2004-04-02 2004-04-02
US60/559,179 2004-04-02
US60/575,468 2004-05-27

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014043650A3 (en) * 2012-09-17 2015-07-16 Theranova, Llc Systems, devices and methods for urine monitoring
CN110269970A (en) * 2019-07-23 2019-09-24 乐山市人民医院 A kind of automatic bladder flusher
CN111263653A (en) * 2017-08-25 2020-06-09 斯特拉塔卡系统有限公司 Urination pump for promoting urine removal from urethra
CN113350654A (en) * 2015-07-20 2021-09-07 斯卓特凯系统有限责任公司 Ureteral and bladder catheters and methods of introducing negative pressure to increase renal perfusion
US11229771B2 (en) 2015-07-20 2022-01-25 Roivios Limited Percutaneous ureteral catheter
US11471583B2 (en) 2015-07-20 2022-10-18 Roivios Limited Method of removing excess fluid from a patient with hemodilution
US11541205B2 (en) 2015-07-20 2023-01-03 Roivios Limited Coated urinary catheter or ureteral stent and method
US11612714B2 (en) 2015-07-20 2023-03-28 Roivios Limited Systems and methods for inducing negative pressure in a portion of a urinary tract of a patient
US11752300B2 (en) 2015-07-20 2023-09-12 Roivios Limited Catheter device and method for inducing negative pressure in a patient's bladder
US11896785B2 (en) 2015-07-20 2024-02-13 Roivios Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
US11918754B2 (en) 2015-07-20 2024-03-05 Roivios Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014043650A3 (en) * 2012-09-17 2015-07-16 Theranova, Llc Systems, devices and methods for urine monitoring
US11541205B2 (en) 2015-07-20 2023-01-03 Roivios Limited Coated urinary catheter or ureteral stent and method
US11896785B2 (en) 2015-07-20 2024-02-13 Roivios Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
CN113350654A (en) * 2015-07-20 2021-09-07 斯卓特凯系统有限责任公司 Ureteral and bladder catheters and methods of introducing negative pressure to increase renal perfusion
US11229771B2 (en) 2015-07-20 2022-01-25 Roivios Limited Percutaneous ureteral catheter
CN113350654B (en) * 2015-07-20 2024-04-12 罗维奥斯有限公司 Ureter and bladder catheter and method of introducing negative pressure to increase renal perfusion
US11420014B2 (en) 2015-07-20 2022-08-23 Roivios Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
US11918754B2 (en) 2015-07-20 2024-03-05 Roivios Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
US11612714B2 (en) 2015-07-20 2023-03-28 Roivios Limited Systems and methods for inducing negative pressure in a portion of a urinary tract of a patient
US11471583B2 (en) 2015-07-20 2022-10-18 Roivios Limited Method of removing excess fluid from a patient with hemodilution
US11752300B2 (en) 2015-07-20 2023-09-12 Roivios Limited Catheter device and method for inducing negative pressure in a patient's bladder
US11904121B2 (en) 2015-07-20 2024-02-20 Roivios Limited Negative pressure therapy system
US11904113B2 (en) 2015-07-20 2024-02-20 Roivios Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
CN111263653A (en) * 2017-08-25 2020-06-09 斯特拉塔卡系统有限公司 Urination pump for promoting urine removal from urethra
CN111263653B (en) * 2017-08-25 2022-06-03 罗维奥斯有限公司 Urinary pump for promoting removal of urine from urethra
CN110269970A (en) * 2019-07-23 2019-09-24 乐山市人民医院 A kind of automatic bladder flusher

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