CN101411606B - Biological measuring system for combined iris and cortex tissue - Google Patents
Biological measuring system for combined iris and cortex tissue Download PDFInfo
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Abstract
The invention provides and realizes a bioassay system for combined iris and cortical tissues, which comprises an optical imaging device, detection and analysis of biological tissue activity, and an assay method based on image analysis. The bioassay system is suitable for all users, has the applicability of common population, and satisfies the scale application based on national level; the most reliable detection and analysis of the biological tissue activity ensure the self-reliability of the bioassay system; and the assay method based on image analysis improves the accuracy and reliability of the performance of the bioassay system.
Description
Technical field
The present invention relates to the optical imaging device of the bioassay system employing of a kind of bioassay system, particularly combined iris and cortical tissue, tissue activity detection analysis reaches based on the graphical analysis assay method.
Background technology
According to inventor's basic research of relevant iris bioassay system in early days, the result of the large sample crowd test by reality, disclose the following improved shortcoming that needs:
1. although the early stage visible iris standard that proposes of the inventor is: at registration time 〉=70%, at comparison time 〉=40%.But the user of about 1%-0.5%, particularly old user is used for analyzed visible iris and is less than 30%, and can not improve; The user of about 0.01%-0.001%, be subjected to all kinds of ocular disease such as degenerative pathology effects, can't be used to the iris bioassay, so demand better is suitable for the bioassay system of whole user, have general crowd's suitability, satisfy based on national sizable application.
2. the reliability of bioassay system itself is that the tissue activity detection analysis function needs further to improve, other is easier to forge as facial and fingerprint etc., comprise about the present known counterfeiting detection method of iris: the iris image periodic frequency of printing, optics red-eye effect and cornea are reflective, and iris pupil changes.But the inventor has obtained confirmation: be higher than under the 20pixel/mm in the iris image resolution quality of printing, make the tissue activity detection analysis inefficacy by the periodic frequency of image low resolution; The eyes cavity body structure of suitable optical material manufacture physiological simulation makes by optics red-eye effect and the reflective tissue activity detection analysis of cornea and lost efficacy; Detect light intensity by photometer, and the pupil of corresponding change false iris might make activity detection analysis lose efficacy.Therefore the tissue activity detection analysis function is very important, and its unreliability causes the unreliability of bioassay system itself.Be badly in need of further better improving the activity detection analysis of bioassay system;
3. demand better improves the performance of bioassay system, comprise: solve the problem that produces mistake when heterphoria when to cause iris deformation to make iris be non-circular, the expression way of better characteristic image, further improve the ability of feature extraction and encoding information entropy, reach and improve the accuracy and reliability that template is estimated, the accuracy and reliability of FAR/FRR.
Summary of the invention
The objective of the invention is to overcome the shortcoming that exists in the above-mentioned prior art, propose and realize a kind of bioassay system, comprise the optical imaging device of the bioassay system employing of combined iris and cortical tissue, tissue activity detection analysis reaches based on the graphical analysis assay method.
It comprises following technical characterictic and content:
The optical imaging device that the bioassay system of a kind of combined iris and cortical tissue adopts is made of light source unit for lighting and image-generating unit, it is characterized in that: light source unit for lighting and image-generating unit are configured to multispectral multi-polarization state combination optical imagine system,
Described multispectral multi-polarization state combination optical imagine system, produce at least four kinds of combined imagings, comprise: black light and orthogonal polarisation state combined imaging, black light and parallel polarization state combined imaging, near infrared light and orthogonal polarisation state combined imaging, and near infrared light and parallel polarization state combined imaging;
Described multispectral multi-polarization state combination optical imagine system comprises:
Light source unit for lighting is by black light at least, the near infrared light light source, and the polarizer constitutes;
Image-generating unit is by black light at least, the near infrared light imaging light path, and analyzer constitutes;
Wherein: described light source unit for lighting and image-generating unit are combined and are configured at least that the wave-length coverage of black light is 300-500nm, the wave-length coverage of near infrared light is 700-900nm, and the polarizer is combined with analyzer and is configured to have at least quadrature and parallel polarization state.
Comprise chromatophorous iris and by the corticoline fabric texture of epithelium/dermis/subcutaneous organizational composition, under multispectral multi-polarization state combination optical imagine system, the combined imaging that obtains is to have visibly different optical signature.
Under the black light image-forming condition different with near infrared light, iris has different spectroscopy difference with the corticoline fabric texture.More specifically, the optical absorption of iris and corticoline fabric texture/reflectance ratio, the contrast near infrared light has 10 times of left and right sides differences under black light.Under the orthogonal polarisation state image-forming condition different with parallel polarization state, iris has different to a greater extent spectroscopy difference with the corticoline fabric texture.More specifically, the optical absorption of iris and corticoline fabric texture/reflectance ratio, contrast parallel polarization attitude has difference more than at least 10 times under orthogonal polarisation state.
Described multispectral multi-polarization state combination optical imagine system, light source unit for lighting and image-generating unit are further increased the combination configuration, and comprising: visible wavelength range is 500-700nm, and the polarizer and analyzer are combined and are configured to the polarization states of 45 degree.The purpose that further increases the combination configuration is for obtaining more different optical signature information about iris and corticoline fabric texture.
Described black light imaging optical path is by near ultraviolet optics narrow band filter, imaging len, and imaging sensor constitutes.
Described near infrared light imaging optical routing near-infrared optical narrow band filter, imaging len, imaging sensor constitutes.
Optical imaging device uses under the complex background environment of practical application, consider the wavelength complexity, non-imaging veiling glares etc. are to the influence of image quality, further, described multispectral multi-polarization state combination optical imagine system, light source unit for lighting and image-generating unit are configured synchronous pulsing light and imaging.
For further improving the ease of use of optical imaging device, be extended to picture unitary imaging viewing field (field ofview), the imaging optical path of described image-generating unit is formed array as lens and imaging sensor and is constituted by form more, and imaging sensor adopts the cmos imaging device of mega pixel level (multi-megapixel) resolution further to obtain bigger imaging viewing field.
The tissue activity detection analysis method that the bioassay system of a kind of combined iris and cortical tissue adopts is characterized in that: may further comprise the steps:
1. the combined imaging of multispectral multi-polarization state combination optical imagine system's generation iris and corticoline fabric texture;
2. produce the biological tissue activity feature detection data of combined imaging image;
3. obtain the normalization comparison value of the biological tissue activity feature detection data of combined imaging image;
4. according to the comparison value term of reference of standard, determine the activity detection analysis result of iris and corticoline fabric texture;
The biological tissue activity feature detection data creating method of described combined imaging image comprises: brightness/contrast analytical method, frequency spectrum analysis method, variance statistical analysis technique.Described biological tissue activity feature detection data produce in the overall situation of combined imaging image and/or local region of interest (ROI), with reliability and the accuracy that further improves the tissue activity detection analysis result.
The normalization comparison value of the biological tissue activity feature detection data of combined imaging image has the advantage of image-forming condition no dependence, so can improve tissue activity detection analysis result's reliability and accuracy.
At last, the comparison value term of reference of the standard that obtains according to priori is determined the activity detection analysis result of iris and corticoline fabric texture if in term of reference, to judge to have activity, otherwise judges and do not have an activity.
In fact, the data that detect the living features that multispectral multi-polarization state combination optical imagine system produces the combined imaging image of iris and corticoline fabric texture have reflected at least that at black light with near infrared light and under the parallel polarization attitude combined imaging condition different with orthogonal polarisation state, iris has different optical absorption/reflectance ratio with the corticoline fabric texture.The combined imaging that obtains is to have visibly different biological tissue spectroscopy feature, and so the tissue activity detection analysis method is tool reliability.
The bioassay system of a kind of combined iris and cortical tissue adopt based on the graphical analysis assay method, it is characterized in that:
May further comprise the steps:
1. define iris and the determined analyzed area of cortical tissue's image;
The determined analyzed area of described iris tissue is defined as model of ellipse,
The determined analyzed area of described cortical tissue is defined as the rotation rectangular model.
2. the determined analyzed area of conversion iris and cortical tissue is iris and cortical tissue's characteristic image;
The method that the determined analyzed area of described iris and cortical tissue is transformed to iris and cortical tissue's characteristic image adopts coordinate space standardization mapping transformation;
3. extract the characteristic information of iris and cortical tissue's characteristic image;
The characteristics information extraction method of described iris and cortical tissue's image adopts Gauss-orthogonal function base small echo (Gauss-Orthogonal function based wavelet) convolution integral iris and cortical tissue's characteristic image of many space displacements multiresolution yardstick multidirectional;
4. produce the feature coding template of iris and cortical tissue's characteristic information;
The method that the feature coding template (BioCode) of described iris and cortical tissue's characteristic information produces adopts the fluctuation status quantization coding (IDCode) of assemblage characteristic information and the energy quality quantization coding (EnergyCode) of characteristic information.
Feature coding template (BioCode)=fluctuation status quantization coding (IDCode)+energy quality quantization coding (EnergyCode).
5. the probability measure between the feature coding template of statistics iris and cortical tissue;
The statistical method of the probability measure between the feature coding template of described iris and cortical tissue adopts:
MD(BioCode1，BioCode2)＝MDstd+MDvalid+MDdb (Eq11)
MDstd＝SameBits/ValidBits
MDvalid＝-0.05*log2(ValidBits/TotalBits)
MDdb＝0.01*log10(db)
SameBits＝||?AND(XORCode，ANDCode)||
ValidBits＝||?ANDCode||
XORCode＝XOR(IDCode1，IDCode2)
ANDCode＝AND(EnergyCode1，EnergyCode2)
BioCode1＝IDCode1+EnergyCode1；
BioCode2＝IDCode2+EnergyCode2；
Wherein:
(BioCode1 BioCode2) is probability measure between the feature coding template to MD;
MDstd is the standard probability measure between the feature coding template;
MDval id is the biasing probability measure of the bits of coded quantity of the logical validity between the feature coding template;
MDdb is the biasing probability measure of the quantity of feature coding template;
Db is the quantity of feature coding template among the data base;
SameBits is the identical bits of coded quantity of logic;
ValidBits is the bits of coded quantity of logical validity;
TotalBits is whole bits of coded quantity;
XORCode is logic XOR (XOR) computing;
ANDCode is logical AND (AND) computing;
|| || be the bits of coded quantity accumulating operation of logical validity;
The bits of coded of described logical validity, promptly logic is 1 bits of coded; The bits of coded that logic is identical, promptly logic is all 1 or 0 bits of coded.
6. according to predetermined probability measure reference value, the probability measure of combination comparison iris and cortical tissue is judged bioassay results.
The probability measure combination comparison method of described iris and cortical tissue adopts two groups to satisfy simultaneously or any one group of satisfied predetermined probability measure reference value.
Sum up foregoing description, technical characterictic and content that the present invention proposes, the bioassay system of combined iris and cortical tissue has the following advantages:
Be suitable for whole user, have general crowd's suitability, satisfy based on national sizable application;
The tissue activity detection analysis of tool reliability is guaranteed reliability of bioassay system itself;
Improve the accuracy and reliability of bioassay system performance.
To and contrast accompanying drawing by specific embodiment below, the present invention is described in further detail.
Description of drawings
Fig. 1 is the optical imaging device schematic diagram of the specific embodiment of the invention 1.
Fig. 2 is the logic configuration figure that the multispectral multi-polarization state combination optical imagine system of the specific embodiment of the invention 1 forms.
Fig. 3 is the tissue activity detection analysis method flow diagram of the specific embodiment of the invention 1.
Fig. 4 be the specific embodiment of the invention 1 based on graphical analysis assay method flow chart.
Fig. 5 is the method flow diagram that the feature coding template (BioCode) of the specific embodiment of the invention 1 produces.
The specific embodiment
Embodiment 1,
Fig. 1 has described the optical imaging device schematic diagram of embodiments of the invention 1, and it specifically comprises:
The shell 0 of airtight optical imaging device, facial iris and corticoline fabric texture 1, the polarizer (2a, 2b), diffusing globe (3a, 3b), black light and near infrared light light source (4a, 4b), optical window 5, light separator 6, near ultraviolet optics narrow band filter 7, near-infrared optical narrow band filter 8, and analyzer (9a, 9b), imaging len (20a, 20b), imaging sensor (21a, 21b), and system's control and processor (30a, 30b).
Black light and near infrared light (4a from light source unit for lighting, 4b), through diffusing globe (3a, 3b), the polarizer (2a, 2b) form illumination path, incide iris and corticoline fabric texture 1 place respectively, in iris and corticoline fabric texture 1, produce optical absorption/reflectance signature then after, return and shine optical window 5, the optical filter of process reflection black light transmission near infrared light forms and analyzer (9a, 9b) Zu He black light imaging optical path (7 as the separation of light separator 6,20a, 21a) and the near infrared light imaging light path (8,20b, 21b), system's control and processor (30a, 30b) all computational methods that are used for bioassay system are handled, control peripheral interface, store template data etc.
Certainly as a kind of optical transform of equivalence, light separator 6 also can be the optical filter of reflect near infrared light transmission black light, and the position of exchange near ultraviolet optics narrow band filter 7 and near-infrared optical narrow band filter 8.
As a kind of optical transform of equivalence, light separator 6 also can be substituted by optical spectroscope equally.
The black light of specific embodiment 1 and near infrared light light source (4a 4b) is made of surface LED (LED), the polarizer of specific embodiment 1 (2a, 2b) and analyzer (9a 9b) is made of polarization state optics element.
Fig. 2 is the logic configuration figure that the multispectral multi-polarization state combination optical imagine system of the specific embodiment of the invention 1 forms, and the logic configuration of clearly having expressed specific embodiment 1 constitutes.Specifically comprise:
Light source unit for lighting and image-generating unit are configured to multispectral multi-polarization state combination optical imagine system.
Light source unit for lighting by black light and near infrared light light source (4a, 4b), and the polarizer (2a 2b) constitutes; Image-generating unit by the black light imaging optical path (7,20a, 21a) and the near infrared light imaging light path (8,20b, 21b) and analyzer (9a 9b) constitutes; The black light imaging optical path is by near ultraviolet optics narrow band filter 7, imaging len 20a, and imaging sensor 21a constitutes.Near infrared light imaging optical routing near-infrared optical narrow band filter 8, imaging len 20b, imaging sensor 21b constitutes.Light source unit for lighting of describing in the specific embodiment 1 and the image-generating unit wave-length coverage that is configured to black light that is combined is 300-500nm, the wave-length coverage of near infrared light is 700-900nm, the polarizer (2a, 2b) and analyzer (9a, 9b) be combined and be configured to have quadrature and parallel polarization state, as adopting 2a and 9a to form orthogonal polarisation state, 2b and 9a form the parallel polarization attitude; 2a and 9b form orthogonal polarisation state, and 2b and 9b form the parallel polarization attitude.
Therefore the multispectral multi-polarization state combination optical imagine system of describing in the specific embodiment 1, produce four kinds of combined imagings, comprise: black light and orthogonal polarisation state combined imaging, black light and parallel polarization state combined imaging, near infrared light and orthogonal polarisation state combined imaging, and near infrared light and parallel polarization state combined imaging.
Although above-mentioned multispectral multi-polarization state combination optical imagine system configuration is optimum for specific embodiment 1, but light source unit for lighting and image-generating unit are further increased the combination configuration: visible wavelength range is 500-700nm, the polarizer and analyzer are combined and are configured to have the polarization state of 45 degree, can further obtain more about the iris optical signature information different with the corticoline fabric texture.
For further improving image quality, the multispectral multi-polarization state combination optical imagine system of describing in the specific embodiment 1, light source unit for lighting and image-generating unit are configured synchronous pulsing light and imaging.
For further improving the ease of use of optical imaging device, be extended to picture unitary imaging viewing field (field ofview), the imaging optical path of image-generating unit is formed array as lens and imaging sensor and is constituted by form more, as constitute the 2X2 array and can expand 4 times imaging viewing field, imaging sensor adopts the cmos imaging device of mega pixel level (multi-megapixel) resolution further to obtain bigger imaging viewing field to increase the working region.
Certainly adopt the early stage technology that proposes of the inventor, optical imaging device has predetermined projection or disperses the optical projection lead beam projection of solid angle or disperse and produces three-dimensional zone and form working region (imaging viewing field), the guiding user can with quicklook easily method be positioned in the working region (imaging viewing field).
Above-mentioned visibly different optical signature information is by the imaging of multispectral multi-polarization state combination optical imagine system in combination, is used for tissue activity detection analysis and based on the graphical analysis assay method.
As shown in Figure 3, the tissue activity detection analysis method that the bioassay system of combined iris and cortical tissue adopts may further comprise the steps:
1. the combined imaging of multispectral multi-polarization state combination optical imagine system's generation iris and corticoline fabric texture;
2. produce the biological tissue activity feature detection data of combined imaging image;
3. obtain the normalization comparison value of the biological tissue activity feature detection data of combined imaging image;
4. according to the comparison value term of reference of standard, determine the activity detection analysis result of iris and corticoline fabric texture;
The biological tissue activity feature detection data creating method of described combined imaging image comprises: brightness/contrast analytical method, frequency spectrum analysis method, variance statistical analysis technique.
Described biological tissue activity feature detection data produce in the overall situation of combined imaging image and/or local region of interest, with reliability and the accuracy that further improves the tissue activity detection analysis result.
The normalization comparison value of the biological tissue activity feature detection data of combined imaging image has the advantage of image-forming condition no dependence, so can improve tissue activity detection analysis result's reliability and accuracy.
At last, the comparison value term of reference of the standard that obtains according to priori is determined the activity detection analysis result of iris and corticoline fabric texture if in term of reference, to judge to have activity, otherwise judges and do not have an activity.
For the multispectral multi-polarization state combination optical imagine system of describing in the specific embodiment 1, produce four kinds of combined imagings, comprise: black light and orthogonal polarisation state combined imaging, black light and parallel polarization state combined imaging, near infrared light and orthogonal polarisation state combined imaging, and near infrared light and parallel polarization state combined imaging.The iris of described four kinds of combined imaging images detects data with corticoline fabric texture living features has reflected that under different image-forming conditions iris has the optical characteristics that different optical absorption/reflectance ratio forms with the corticoline fabric texture.The combined imaging that obtains is to have visibly different spectroscopy feature, and so the tissue activity detection analysis method is tool reliability.
As shown in Figure 4, the bioassay system of combined iris and cortical tissue adopt based on the graphical analysis assay method, may further comprise the steps:
1. define iris and the determined analyzed area of cortical tissue's image.
The determined analyzed area of described iris tissue is defined as model of ellipse.
The determined analyzed area of described cortical tissue is defined as the rotation rectangular model.
(ap bp) is the model of ellipse Ep of iris tissue inner boundary pupil for xp, yp
[(x-xp)/ap]
2+[(y-yp)/bp]
2＝1 (Eq1)
(ai bi) is the model of ellipse Ei of iris tissue external boundary for xi, yi
[(x-xi)/ai]
2+[(y-yi)/bi]
2＝1 (Eq2)
Wherein:
(xp yp) is the centre coordinate of iris tissue inner boundary pupil, and (ap bp) is the X of iris tissue inner boundary pupil, the ellipse length of Y-axis;
(xi yi) is the centre coordinate of iris tissue external boundary, and (ai bi) is the X of iris tissue external boundary, the ellipse length of Y-axis; When heterphoria when to cause iris deformation to make iris be non-circular, the iris tissue that is defined as model of ellipse can address this problem.Further, consider actual iris deformation situation, the parameter-definition territory that further limits model of ellipse is to lower computation complexity:
The determined analyzed area of described cortical tissue is defined as rotation rectangular model I (x ', y '):
I(x’，y’)＝Roation(θ)Rect(x，y)； (Eq3)
Wherein: Roation (θ) is a spin matrix, and (x y) is rectangular model to Rect, and Xl and Xr are that (Yt and Yb are rectangular model Rect (x, Y-axis up-and-down boundary y) to rectangular model Rect for x, border, X-axis left and right sides y).θ is rectangular model Rect (x, y) anglec of rotation of relative X-Y coordinate axes.
The important characteristic of the determined analyzed area define method of iris of the present invention and cortical tissue's image is: set up the only in essence mathematical expression model of determined analyzed area, for the performance that improves bioassay system lays the foundation.
2. the determined analyzed area of conversion iris and cortical tissue is iris and cortical tissue's characteristic image;
The method that the determined analyzed area of described iris and cortical tissue is transformed to iris and cortical tissue's characteristic image adopts coordinate space standardization mapping transformation.
The determined analyzed area coordinate space of described iris tissue standardization mapping transformation be iris tissue characteristic image I (x, y),
Wherein: r ∈ [0,1], Ф ∈ [1,1];
[xp (Ф), yp (Ф)] is the coordinate space position of the model of ellipse of satisfied following iris tissue inner boundary pupil,
Or of equal value
[xi (Ф), yi (Ф)] is the coordinate space position of the model of ellipse of satisfied following iris tissue external boundary,
Or of equal value
The determined analyzed area coordinate space standardization mapping transformation of described cortical tissue be the characteristic image I of cortical tissue (x, y): I (x ', y ') :-＞I (x, y) (EQ5)
Be summed up as with cortical tissue analyzed mensuration area I (x ', y ') and have identical coordinate space expression way, therefore directly the code requirement mapping transformation generation characteristic image I of cortical tissue (x, y).
After being appreciated that the discrete sampling of above-mentioned coordinate space standardization mapping transformation mathematics is expressed, has the characteristic image of unified standard yardstick.The important characteristic of coordinate space standardization mapping transformation method of the present invention is: by coordinate space standardization mapping transformation, iris and cortical tissue analyzed mensuration zone becomes iris and cortical tissue's characteristic image, not only making follow-up institute have normalized unified standard in steps handles, and has an image translation, rotation, image-forming condition no dependences such as convergent-divergent promptly do not have dependency.
Following content description is handled iris and cortical tissue's characteristic image with identical method.
3. extract the characteristic information of iris and cortical tissue's characteristic image;
The characteristics information extraction method of described iris and cortical tissue's characteristic image adopts Gauss-orthogonal function base small echo (Gauss-Orthogonal function based wavelet) convolution integral iris and cortical tissue's characteristic image of many space displacements multiresolution yardstick multidirectional.
Described Gauss-orthogonal function base small echo (Gauss-Orthogonal function based wavelet) prototype be G (x, y),
G(x，y)＝Gauss(x，y)*Orth(x，y) (Eq6)
Wherein: Gauss (x y) is two-dimensional Gaussian function (2D Gauss function), and Orth (x is two-dimensional quadrature function (2D Orthogonalfunction) y), as Sin/Cos, and Hermite, Chebyshev, Laguerre, orthogonal functions such as Legerdre.
(x y) has following mathematical feature: Gauss-orthogonal function base small echo is combined by Gaussian function and orthogonal function described Gauss-orthogonal function base small echo G.Possess and make any analytic signal can both be at [∞, + ∞] be broken down into complete orthogonal function linear combination in the spatial domain, more importantly, complete orthogonal property has the Analytical Expression ability that no dependency is a redundancy to analytic signal, can reflect the maximization comentropy that analytic signal comprises.Gaussian function possesses in conjunction with the minimum indeterminacy precision in space/frequency domain, has optimum space/frequency localization window, with Gaussian function as the constraint window, the spatial domain that makes orthogonal function is from [∞, + ∞] convergence, be defined as tight support, have optimum space/frequency localization characteristic.Understand from the signal analysis angle, Gauss-orthogonal function base small echo has the characteristic of equivalence zone passband limit wave filter.
Above-mentioned Gauss-orthogonal function base small echo G (x, y), through space displacement, resolution-scale convergent-divergent, direction is rotated, and forms the Gauss-orthogonal function base small echo Gs of many space displacements multiresolution yardstick multidirectional, xo, yo, θ (x, y):
Wherein: s is the resolution-scale parameter, and xo, yo are the space displacement parameter, and θ is a direction anglec of rotation parameter.
The Gauss of many space displacements multiresolution yardstick multidirectional-orthogonal function base small echo Gs, xo, yo, θ (x, y) convolution integral iris and the characteristic image I of cortical tissue (x, y) be used for producing and characteristic information extraction W (s, xo, yo, θ):
W(s，xo，yo，θ)＝∫∫I(x，y)Gs，xo，yo，θ(x，y)dxdy (Eq8)
According to information theory, to any analytic signal is characteristic image, the characteristic information spatial coherence length that the said extracted method obtains is more than or equal to the frequency bandwidth inverse of wavelet filter, and and if only if characteristic information frequency dependence bandwidth when equaling the frequency bandwidth of wavelet filter equal sign set up.
The important characteristic of the characteristics information extraction method of iris of the present invention and cortical tissue's characteristic image is: the Gauss of many space displacements multiresolution yardstick multidirectional-orthogonal function base small echo convolution integral iris and cortical tissue's characteristic image possess optimum in conjunction with space/frequency localization analysis ability, extract the comentropy maximization that characteristic image comprises.
4. produce the feature coding template of iris and cortical tissue's characteristic information;
The method that described feature coding template (BioCode) produces adopts the fluctuation status quantization coding (IDCode) of assemblage characteristic information and the energy quality quantization coding (EnergyCode) of characteristic information.Promptly can be expressed as:
Feature coding template (BioCode)=fluctuation status quantization coding (IDCode)+energy quality quantization coding (EnergyCode).As Fig. 5, the method that described feature coding template (BioCode) produces specifically may further comprise the steps:
The down-sampled characteristic information W 4.1 standardize (s, xo, yo, θ).
The frequency dependence bandwidth that the down-sampled frequency of described standardization obtains smaller or equal to characteristic information, or of equal value, the spatial coherence length that the down-sampled space length that standardizes obtains more than or equal to characteristic information.
The down-sampled reason of code requirementization is to consider:
A. space/frequency domain resolution of comprising of characteristic information itself is a restricted gender, and it has band passband limit characteristic.
B. reduce computation complexity, be easy to real-time processing.
C. maximize the encoding information entropy that the feature coding template comprises.
D. normalized unified standard coded sample is arranged and can be improved treatment effeciency and improve stability.
4.2 fluctuation status quantization coding (IDCode),
Wherein: n, m 〉=0 is the partial differential exponent number.
If promptly
N+m/
nx
mY[W (s, xo, yo, θ)] 〉=0 be encoded to binary logic 1, otherwise be encoded to binary logic 0.
Energy quality quantization coding (EnergyCode)
Wherein: E is an energy quality control threshold value.
That is, if | W (s, xo, yo, θ) |
2〉=E is encoded to binary logic 1, otherwise is encoded to binary logic 0.
The reflection of fluctuation status quantization coding production method is to the variation characteristic information representation of the fluctuation status of individual features information, and coding 1 or 0 representative is the logic quantification of maximum/minimum two states to the partial differential polarity of the fluctuation status of characteristic information.
The reflection of energy quality quantization coding production method is to the control characteristic information representation of the energy quality of individual features information, coding 1 or 0 representative to the effectiveness of the energy quality of characteristic information promptly effectively/logic of invalid two states quantizes.
The important characteristic of feature coding method of iris of the present invention and cortical tissue's characteristic information is: the coded method of fluctuation status quantization has the maximization encoding information entropy that produces characteristic information, possess to as the illumination, focus on, gain, image-forming condition no dependence or dependencys such as contrast, energy quality quantization coding has control action to the effectiveness of the energy quality of characteristic information.
5. the probability measure between the feature coding template of statistics iris and cortical tissue;
The statistical method of the probability measure between described feature coding template adopts:
MD(BioCode1，BioCode2)＝MDstd+MDvalid+MDdb (Eq11)
MDstd＝SameBits/ValidBits
MDvalid＝-0.05*log2(ValidBits/TotalBits)
MDdb＝0.01*log10(db)
SameBi?ts＝||?AND(XORCode，ANDCode)||
ValidBits＝||?ANDCode||
XORCode＝XOR(IDCode1，IDCode2)
ANDCode＝AND(EnergyCode1，EnergyCode2)
BioCode1＝IDCode1+EnergyCode1；
BioCode2＝IDCode2+EnergyCode2；
Wherein:
(BioCode1 BioCode2) is probability measure between the feature coding template to MD;
MDstd is the standard probability measure between the feature coding template;
MDvalid is the biasing probability measure of the bits of coded quantity of the logical validity between the feature coding template;
MDdb is the biasing probability measure of the quantity of feature coding template;
Db is the quantity of feature coding template among the data base;
SameBits is the identical bits of coded quantity of logic;
ValidBits is the bits of coded quantity of logical validity;
TotalBits is whole bits of coded quantity;
XORCode is logic XOR (XOR) computing;
ANDCode is logical AND (AND) computing;
|| || be the bits of coded quantity accumulating operation of logical validity;
The bits of coded of described logical validity, promptly logic is 1 bits of coded; The bits of coded that logic is identical, promptly logic is all 1 or 0 bits of coded.
The important characteristic of statistical method of the probability measure between iris of the present invention and cortical tissue's feature coding template is: possess image-forming condition no dependence or dependency, have logic coding position i.e. only statistic logic efficient coding position and the biasing probability measure of removing invalid characteristic information according to the energy quality control action of characteristic information, improve the accuracy and reliability of feature coding template probability measure.
6. according to predetermined probability measure reference value, the probability measure of combination comparison iris and cortical tissue is judged bioassay results.
The probability measure combination comparison method of described iris and cortical tissue adopts two groups to satisfy simultaneously or any one group of satisfied predetermined probability measure reference value.
If FAR1, FAR2 is respectively the false acceptance rate degree of accuracy of the predetermined probability measure reference value of iris and cortical tissue, if FRR1, FRR2 is respectively the false rejection rate degree of accuracy of the predetermined probability measure reference value of iris and cortical tissue, two groups of false acceptance rate degree of accuracy that satisfy the combination comparison of the predetermined probability measure reference value of iris and cortical tissue simultaneously are FARboth, the false rejection rate degree of accuracy is FRRboth, so
FARboth＝FAR1*FAR2 (Eq12)
FRRboth＝1-(1-FRR1)*(1-FRR2)
Any one group of false acceptance rate degree of accuracy that satisfies the combination comparison of the predetermined probability measure reference value of iris and cortical tissue is FARany, and the false rejection rate degree of accuracy is FRRany, so
FARany＝1-(1-FAR1)*(1-FAR2) (Eq13)
FRRany＝FRR?1*FRR2
The important characteristic of probability measure combination comparison method of iris of the present invention and cortical tissue is: select the predetermined probability measure reference value by the priori acquisition, by the probability measure combination comparison method of iris and cortical tissue, comprehensively improve the accuracy and reliability of bioassay system thus.
When practical application, all aforementioned calculation methods can both be expressed with the mathematics discrete form, and can be by optimizing integer code real-time implementation.
Although the description content mediopellis biological tissue at this specific embodiment is defined as facial zone, as popularization of equal value, other zone also can be understood by the specific embodiment equivalence and be adopted as palmar hand corticoline fabric texture.
The specific embodiment content that the present invention describes, under technical characterictic and content request, can be identical or be equal in the scope of understanding and make up mutually, operations such as modification and increase and decrease are implemented to carry out specific embodiment, as adopt that light path equivalence transformation, concrete structure distortion of equal value, step equivalence are replaced etc.
Claims (6)
1. the optical imaging device that adopts of the bioassay system of combined iris and cortical tissue is made of light source unit for lighting and image-generating unit, it is characterized in that:
Light source unit for lighting and image-generating unit are configured to multispectral multi-polarization state combination optical imagine system, at least four kinds of combined imagings of described multispectral multi-polarization state combination optical imagine system's generation, comprise: black light and orthogonal polarisation state combined imaging, black light and parallel polarization state combined imaging, near infrared light and orthogonal polarisation state combined imaging, and near infrared light and parallel polarization state combined imaging;
Described multispectral multi-polarization state combination optical imagine system comprises:
Light source unit for lighting is at least by the black light light source, and the near infrared light light source reaches the polarizer and constitutes;
Image-generating unit is at least by the black light imaging optical path, and the near infrared light imaging light path reaches analyzer and constitutes;
Wherein: described light source unit for lighting and image-generating unit are combined and are configured at least that the wave-length coverage of black light is 300-500nm, the wave-length coverage of near infrared light is 700-900nm, and the polarizer is combined with analyzer and is configured to have at least quadrature and parallel polarization state.
2. the optical imaging device that the bioassay system of combined iris according to claim 1 and cortical tissue adopts is characterized in that:
Described multispectral multi-polarization state combination optical imagine system, light source unit for lighting and image-generating unit are further increased the combination configuration and comprise: visible wavelength range is 500-700nm, the polarizer and analyzer are combined and are configured to the polarization states of 45 degree.
3. the optical imaging device that the bioassay system of combined iris according to claim 1 and cortical tissue adopts is characterized in that:
Described black light imaging optical path is by near ultraviolet optics narrow band filter, imaging len, and imaging sensor constitutes;
Described near infrared light imaging optical routing near-infrared optical narrow band filter, imaging len, imaging sensor constitutes.
4. the optical imaging device that the bioassay system of combined iris according to claim 1 and cortical tissue adopts is characterized in that:
Described light source unit for lighting and image-generating unit are configured synchronous pulsing light and imaging;
The imaging optical path of described image-generating unit is formed array as lens and imaging sensor and is constituted by form more,
And imaging sensor adopts the cmos imaging device of mega pixel class resolution ratio.
5. the tissue activity detection analysis method that adopts of the bioassay system of combined iris and cortical tissue, it adopts the described multispectral multi-polarization state combination optical imagine of claim 1 system, it is characterized in that: may further comprise the steps:
(1) the combined imaging image of multispectral multi-polarization state combination optical imagine system's generation iris and corticoline fabric texture;
(2) the biological tissue activity feature detection data of generation combined imaging image;
(3) the normalization comparison value of the biological tissue activity feature detection data of acquisition combined imaging image;
(4), determine the activity detection analysis result of iris and corticoline fabric texture according to the comparison value term of reference of standard.
6. the tissue activity detection analysis method that the bioassay system of combined iris according to claim 5 and cortical tissue adopts is characterized in that:
The biological tissue activity feature detection data creating method of described combined imaging image comprises: brightness/contrast analytical method, frequency spectrum analysis method, variance statistical analysis technique;
Described biological tissue activity feature detection data produce in the overall situation of combined imaging image and/or local region of interest.
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| CN108510470B (en) * | 2018-02-12 | 2020-08-04 | 佛山市顺德区中山大学研究院 | Method for extracting transition-period sheet corneal ulceration area by super pixels |
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