CN101396495B - Traditional Chinese medicine for treating cardiovascular and cerebrovascular disease - Google Patents
Traditional Chinese medicine for treating cardiovascular and cerebrovascular disease Download PDFInfo
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- CN101396495B CN101396495B CN2007101896420A CN200710189642A CN101396495B CN 101396495 B CN101396495 B CN 101396495B CN 2007101896420 A CN2007101896420 A CN 2007101896420A CN 200710189642 A CN200710189642 A CN 200710189642A CN 101396495 B CN101396495 B CN 101396495B
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Abstract
The invention relates to a traditional Chinese drug for treating cardiovascular and cerebrovascular diseases. The traditional Chinese drug is made from the following components by weight: 0.3-5 parts of dragons blood, 0.1-1 part of borneol, 2-15 parts of notoginseng, 10-80 parts of red peony root and 10-30 parts of beggarticks. The combined use of the components of the traditional Chinese drug can effectively treat the cardiovascular and cerebrovascular diseases, has apparent blood vessel dilation function, and can significantly improve the blood supply to infraction parts of patients with cardiovascular and cerebral infarction. The drug has adequate analgesic function since pain is caused by obstruction and no pain exists after removal of the obstruction. The traditional Chinese drug can cause the pain of patients with angina pectoris to disappear in about one week, has obvious function of lowering blood fat, and can effectively clean blood vessels and rapidly dissolve fibrin in thrombi and plaques on vascular wall. The traditional Chinese drug can significantly relieve the symptoms of patients with the cardiovascular and cerebrovascular diseases; avoid pain of some patients resulting from operative treatment; greatly reduce the treatment expenses, and significantly lower the treatment cost, thus the traditional Chinese drug is acceptable for most patients.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of cardiovascular and cerebrovascular disease, belong to technical field of Chinese medicines.
Background technology
Along with social senilization and growth in the living standard, the sickness rate and the case fatality rate of cardiovascular and cerebrovascular disease rise day by day, according to the survey, ischemic heart desease and cerebrovascular disease have become the main cause of death, in addition, also have a large amount of cardiovascular and cerebrovascular disease patients to become the important crowd who needs medical care.Studies show that have 60% patient to die from cardiovascular and cerebrovascular disease, as seen nurse one's health blood fat, the health of protection blood vessel, softening cleaning blood vessel rubbish is for guaranteeing that people's is healthy extremely important.The pathogenic factor of cardiovascular and cerebrovascular disease is because endovascular rubbish is the fibrin that triglycerides, cholesterol, lipid peroxidation, low-density albumen form is fixed on the blood vessel wall, formation is as the speckle of Stalactitum, in the course of time, cause sclerosis of blood vessels, obstruction, and existing medicine is difficult to these materials are disposed.At present, the medicine that is used for the treatment of cardiovascular and cerebrovascular disease is a lot, logical etc. as SUXIAO JIUXIN WAN, Radix Salviae Miltiorrhizae drop pill, Radix Salviae Miltiorrhizae Tabellae, FUFANG DANSHEN PIAN, the network heart, these medicines are through behind the life-time service, most of cardiacs also keep away unavoidably puts support and bypass surgery and handles, and needs a large amount of money of cost, and the medicine of existing treatment cardiovascular and cerebrovascular disease in the blood and the speckle of blood vessel wall, blood fat etc. old and feeble plain remove ineffective, or can not remove, therefore can not eradicate to angiopathy. at all
Summary of the invention
The object of the present invention is to provide a kind of therapeutic effect good, cost is low, the Chinese medicine of the treatment cardiovascular and cerebrovascular disease that has no side effect.
To achieve these goals, technical program of the present invention lies in adopting a kind of Chinese medicine for the treatment of cardiovascular and cerebrovascular disease, be prepared from by the component of following parts by weight:
Resina Draconis 0.3-5 part Borneolum Syntheticum 0.1-1 part Radix Notoginseng 2-15 part
Radix Paeoniae Rubra 10-80 part Herba Bidentis Bipinnatae 10-30 part.
Chinese medicine of the present invention preferably is prepared from by the component of following parts by weight:
Resina Draconis 0.5-3 part Borneolum Syntheticum 0.2-0.8 part Radix Notoginseng 3-12 part
Radix Paeoniae Rubra 20-60 part Herba Bidentis Bipinnatae 15-25 part.
In each component of the present invention, Resina Draconis, GUIXIN, Liver Channel, sweet flat, no obvious toxic and side effects has good analgesic activity, and the promoting blood circulation and hemostasis two-way function is stopped blooding and is not flowed the stasis of blood; Anti thrombotic action, the platelet increasing electrophoretic velocity has reduction trend to the viscosity of blood, can increase the active unit of lyase, promotes fibrinolytic.Borneolum Syntheticum, the GUIXIN lung meridian, pharmacological action is: pain relieving, antiinflammatory, inducing resuscitation, treatment apoplexy locked mouth, practical observation has significant blood vessel dilating effect.Radix Notoginseng, sweet, little hardship, temperature, has certain short sleep effect, obviously analgesic activity and anti-arrhythmia effect have antagonism to the mice atrial fibrillation, can eliminate the ventricular premature contraction or the chamber sinus tachycardia that are caused by chemical substance, coronary artery dilator, increase coronary flow, improve the survival rate of core cell under the anaerobic condition, Radix Notoginseng total arasaponins can obviously dwindle cardiac muscle and lack heart district area; In addition, also have hypotensive effect, its action principle and Radix Notoginseng total arasaponins can block the outer Ca of born of the same parents
2+Ca in interior stream and the inhibition cell
2+Release action similar; The arteriosclerosis effect, Radix Notoginseng total arasaponins can significantly suppress the formation of experimental atherosclerosis speckle; The two-way function that hemostasis is arranged and invigorate blood circulation; Suppress fibrinous formation, promote the fibrinolytic effect; To the effect of blood fat, Radix Notoginseng powder can stop the absorption of intestinal to fat, and the cholesterol in the serum and the content of triglyceride acid are significantly reduced, and the arteries fat deposit significantly reduces; Lipid peroxidation in the blood is significantly reduced, can also make in the blood SOD particularly the fork of the oxidation in brain enzymatic activity significantly raise.Radix Paeoniae Rubra, the hardship that is slightly cold is returned Liver Channel, eliminating stasis to stop pain, and obviously the formation of the inside and outside thrombosis of extension body alleviates the thrombosis dry weight; Can directly improve CaAMP content in the cell, the activity of activation fiber lyase is dissolved the fibrin that is fixed on the blood vessel wall; Suppress the platelet consolidation; The stagnant blood coronary heart disease of high viscosity had the effect of the hemorheological property of change; blood viscosity relatively significantly reduces before the medication; heart there is protective effect; coronary blood flow increasing 28.4%, expansion lung cardiovascular improves pulmonary circulation; calmness and spasmolysis are arranged; the liver protecting promotes the synthetic increase of DNA, promotes the liver detoxification effect.Herba Bidentis Bipinnatae contains anthraquinone glycoside, and property is flat, and bitter in the mouth can reduce triglyceride in the blood, cholesterol, reduces the viscosity of blood.All medicines of the present invention share, and can effectively treat cardiovascular and cerebrovascular disease, have tangible blood vessel dilating effect, can significantly improve the amount of blood supply of blocking part to the heart and brain infarct victims; Enough analgesic activities are arranged, and pain is then obstructed, general rule not bitterly, Chinese medicine of the present invention can make patient with angina pectoris one all left and right sides pain disappear; Have tangible effect for reducing blood fat, can effectively clear up blood vessel, rapidly the fibrin in the speckle on thrombus and the blood vessel wall.Cardiovascular and cerebrovascular disease patient symptom after taking Chinese medicine of the present invention is significantly improved, the patient who has has avoided the misery of operative treatment, medical expense significantly reduces, the treatment cost that originally needs units up to ten thousand, taking Chinese medicine of the present invention only needs hundreds of unit just can cure, greatly reduce the treatment cost, be easy to be accepted by extensive patients.There is the patient who can't take care of oneself originally about 70% after taking Chinese medicine of the present invention, not only can take care of oneself, but also can be engaged in housework and work.Chinese medicine of the present invention can be any dosage form.
Chinese medicine application of treatment cardiovascular and cerebrovascular disease in early stage 111 examples of the present invention, cure rate reaches 70%, shows as transference cure, and recovers operate as normal; Effective percentage reaches 100%, shows as transference cure, but can not recover operate as normal fully.
Preparation method of Chinese medicine of the present invention is: earlier the Radix Paeoniae Rubra of 10-80 part, the Herba Bidentis Bipinnatae of 10-30 part are heated concentrated extract with ethanol, after the drying, add Resina Draconis 0.3-5 part, Borneolum Syntheticum 0.1-part, Radix Notoginseng 2-15 part, mix homogeneously, be ground into the 140-160 order, go into capsule then and get final product.
The specific embodiment
Embodiment 1
The Chinese medicine that the present invention treats cardiovascular and cerebrovascular disease is prepared from by the component of following parts by weight:
2 parts of 0.1 portion of Radix Notoginseng of 0.3 part of Borneolum Syntheticum of Resina Draconis
10 parts of 10 portions of Herba Bidentis Bipinnatae of Radix Paeoniae Rubra.
The preparation method of Chinese medicine of present embodiment is: be that 10 parts Radix Paeoniae Rubra, 10 parts Herba Bidentis Bipinnatae are heated concentrated extract with ethanol with parts by weight earlier, after the spray drying, add 0.3 part of Resina Draconis, 0.1 part of Borneolum Syntheticum, 2 parts of Radix Notoginseng, mix homogeneously, be ground into 150 orders in the lump, go into capsule then and get final product.
Embodiment 2
The Chinese medicine that the present invention treats cardiovascular and cerebrovascular disease is prepared from by the component of following parts by weight:
8 parts of 0.5 portion of Radix Notoginseng of 2 parts of Borneolum Syntheticums of Resina Draconis
20 parts of 40 portions of Herba Bidentis Bipinnatae of Radix Paeoniae Rubra.
Embodiment 3
The Chinese medicine that the present invention treats cardiovascular and cerebrovascular disease is prepared from by the component of following parts by weight:
15 parts of 1 portion of Radix Notoginseng of 5 parts of Borneolum Syntheticums of Resina Draconis
30 parts of 80 portions of Herba Bidentis Bipinnatae of Radix Paeoniae Rubra.
Clinical case of the present invention is as follows:
Lee XX
The woman, 64 years old, heart disease 6 years, blood pressure systolic pressure 160-170mmHg, diastolic pressure 100-110mmHg is through the Chinese People's Liberation Army's 153 examination in hospital, be cardiovascular and cerebrovascular disease, show as uncomfortable in chest, hyperlipidemia, during morbidity, the lip blue can not be walked, and can not work, need weekly to have an injection in hospital once, be with SUXIAO JIUXIN WAN, FUFANG DANSHEN PIAN all day, depressor is continuous, and the doctor requires to perform an operation to put support.Behind the oral Chinese medicine of the present invention, all cardiotropic formulations and the depressor that have stopped taking originally, self-after two months symptom complete obiteration, blood pressure on inspection, it is normal that blood fat and electrocardiogram all recover.After oral four months, can do all housework, and pick child and go to school, not have any clinical symptoms, blood pressure maintains between the systolic pressure 130-140mmHg all the time, between the diastolic pressure 80-90mmHg, follows up a case by regular visits to 2 years, does not see recurrence.
Old XX
The woman, 67 years old, surplus the hypertension, heart disease 20 year, blood pressure systolic pressure 190-210mmHg, heart is overrun, heart rate 100 times/minute.Merge Meniere, both legs are unable, can not walk, and hospitalization repeatedly once, successively oral nimodipine, voltage stabilizing are quiet, troxerutin, Luo Buma, Radix Salviae Miltiorrhizae Tabellae etc.In case drug withdrawal, systolic pressure just rise to 210mmHg.Begin oral Chinese medicine of the present invention in March, 2007, takes after two months above-mentioned symptom and disappear, and diet and defecation are normal, blood pressure stabilization is about 150/90mmHg, limbs are movable, and can be by tricycle, body weight is reduced to present 60kg by original 70kg, and conscious health is easily a lot.
Du XX
The man, 69 years old, obesity, body weight 90kg, hyperlipidemia, blood viscosity height, health is stranded heavy, and not high with parkinson disease, a hand tremor, blood pressure, it is light from head to foot that oral Chinese medicine of the present invention promptly felt in 1 month, 5.5kg loses weight, appetite increases, and health is strong, and the parkinson disease symptom also greatly alleviates, followed up a case by regular visits to satisfactory effect 4 years.
Old XX
The woman, 55 years old, the retired professor, blood pressure 160/90mmHg had the coronary disease medical history 10 years, and symptom is uncomfortable in chest, can not go upstairs, asthma, oral Chinese medicine 1 all backs above-mentioned symptom of the present invention greatly alleviates, and does not have the asthma phenomenon upstairs, and the blood pressure recovery is normal, follows up a case by regular visits to 2 years, does not see recurrence.
Still XX
The man, 67 years old, the engineer, multiple cerebral infarction medical history 10 years, the blood pressure systolic pressure is more than 170mmHg, can't walk, dizziness, both legs are unable, and oral Chinese medicine of the present invention is the lower-limb muscular strength increase after 10 days, orally can walk after two months, it is normal that blood pressure recovers, and followed up a case by regular visits to 2 years, do not recur.
King XX
The woman, 60 years old, the retired professor, coronary heart disease medical history 9 years, uncomfortable in chest, asthma need be laid support through hospital therapy, and an oral course of treatment of Chinese medicine of the present invention (2 months) back above-mentioned symptom disappears, and can stem portion housework, follows up a case by regular visits to 2 years, does not see recurrence.
Wu XX
The woman, 56 years old, coronary heart disease medical history 5 years, uncomfortable in chest, hyperlipidemia, oral Chinese medicine two weeks of the present invention, above-mentioned symptom is greatly improved, and above-mentioned symptom disappears after oral 2 months, and recovers operate as normal, follows up a case by regular visits to 3 years, does not see recurrence.
Still XX
The man, hyperlipidemia medical history 20 years is with dizziness, oral Chinese medicine of the present invention is after 2 weeks, blood fat recovers normal on inspection, and cholesterol level drops to 5.79 by 7.04, and triglyceride drops to 1.88 by 2.2, low-density albumen drops to 4.04 by 4.99, blood glucose drops to 4.45 by 5.53, and high-density protein is raised to 1.39 by 1.2, and feels transference cure, followed up a case by regular visits to 2 years, and do not see recurrence.
It should be noted last that: above embodiment is the unrestricted technical scheme of the present invention in order to explanation only, although the present invention is had been described in detail with reference to the foregoing description, those of ordinary skill in the art is to be understood that: still can make amendment or be equal to replacement the present invention, and not breaking away from any modification or partial replacement of the spirit and scope of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.
Claims (1)
1. Chinese medicine for the treatment of cardiovascular and cerebrovascular disease, it is characterized in that: the component by following parts by weight is prepared from:
Sanguis Draxonis 0.5-3 part Borneolum Syntheticum 0.2-0.8 part Radix Notoginseng 3-12 part
Radix Paeoniae Rubra 20-60 part Herba Bidentis Bipinnatae 15-25 part, described Chinese medicinal preparation method is: earlier Radix Paeoniae Rubra, Herba Bidentis Bipinnatae heated concentrated extract with ethanol, after the drying, adds Sanguis Draxonis, Borneolum Syntheticum, Radix Notoginseng, mix homogeneously is ground into the 140-160 order, goes into capsule then and gets final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2007101896420A CN101396495B (en) | 2007-09-26 | 2007-09-26 | Traditional Chinese medicine for treating cardiovascular and cerebrovascular disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101896420A CN101396495B (en) | 2007-09-26 | 2007-09-26 | Traditional Chinese medicine for treating cardiovascular and cerebrovascular disease |
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| Publication Number | Publication Date |
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| CN101396495A CN101396495A (en) | 2009-04-01 |
| CN101396495B true CN101396495B (en) | 2011-03-30 |
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| CN2007101896420A Expired - Fee Related CN101396495B (en) | 2007-09-26 | 2007-09-26 | Traditional Chinese medicine for treating cardiovascular and cerebrovascular disease |
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Families Citing this family (1)
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| WO2023066162A1 (en) * | 2021-10-18 | 2023-04-27 | 苏州沪云新药研发股份有限公司 | Use of borneol in preparation of drug for treatment of cerebral ischemic stroke |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1198342A (en) * | 1997-03-27 | 1998-11-11 | 崔兴 | Medicine series for preventing and curing hypotension, angiocardiopathy and cerebrovascular disease and productive method thereof |
| CN1470268A (en) * | 2003-04-25 | 2004-01-28 | 云南省个旧市药业有限责任公司 | Compound Longxue scorpion and preparation method thereof |
| CN101085064A (en) * | 2006-06-08 | 2007-12-12 | 天津天士力制药股份有限公司 | Composition containing radix paeoniae rubrathe for treating cardiovascular diseases and its preparation |
-
2007
- 2007-09-26 CN CN2007101896420A patent/CN101396495B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1198342A (en) * | 1997-03-27 | 1998-11-11 | 崔兴 | Medicine series for preventing and curing hypotension, angiocardiopathy and cerebrovascular disease and productive method thereof |
| CN1470268A (en) * | 2003-04-25 | 2004-01-28 | 云南省个旧市药业有限责任公司 | Compound Longxue scorpion and preparation method thereof |
| CN101085064A (en) * | 2006-06-08 | 2007-12-12 | 天津天士力制药股份有限公司 | Composition containing radix paeoniae rubrathe for treating cardiovascular diseases and its preparation |
Non-Patent Citations (2)
| Title |
|---|
| 杨坚毅.冠心病心绞痛中医药治疗研究进展.《湖北中医杂志》.2002,第24卷(第8期),第53-56页. * |
| 阮金兰等.赤芍化学成分和药理作用的研究进展.《中国药理学通报》.2003,第19卷(第9期),第965-970页. * |
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