CN101390749B - Near infrared detection probe for mammary tissue - Google Patents
Near infrared detection probe for mammary tissue Download PDFInfo
- Publication number
- CN101390749B CN101390749B CN2008102254454A CN200810225445A CN101390749B CN 101390749 B CN101390749 B CN 101390749B CN 2008102254454 A CN2008102254454 A CN 2008102254454A CN 200810225445 A CN200810225445 A CN 200810225445A CN 101390749 B CN101390749 B CN 101390749B
- Authority
- CN
- China
- Prior art keywords
- light source
- photodetector
- near infrared
- wire resistance
- slide wire
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Disclosed is a breast tissue near infrared detection probe, belonging to breast tissue near infrared detection technical field. The breast tissue near infrared detection probe is characterized in that a displacement detector is arranged between a light source and a photodetector; the moveable end of the slider resistor is connected to the shell of the photodetector through a down-lead, and the fixed end of the slider resistor is connected to the shell of the light source; or that the moveable end of the slider resistor is connected to the shell of the light source and the fixed end of the slider resistor is connected to the photodetector. With the change of the linear distance between the light source and the photodetector, the moveable end correspondingly moves on the slider resistor.
Description
Technical field
The invention belongs to the complex art field that near-infrared laser, computer, machinery, electronics and Flame Image Process are used in biomedicine.
Background technology
Mastopathy is one of multiple disease of women, and sickness rate rises in recent years, has become first malignant tumor of China women, so the generaI investigation of mammary gland tissue and early diagnosis work are very important.Mostly adopt Mammography or CR technology to generally investigate, diagnose at present, though they have higher recall rate ratio, efficient is low, and the expense height has injury to human body.Image checks such as general X ray, B ultrasonic need possess certain density resolution, only the lump that occurs in canceration reaches just meeting video picture more than the 2mm, and when mammary gland generation canceration, occur in mammary gland tip catheter lobule at first, from the atypical hyperplasia to the cancer in situ, more all be confined to leaflet tissue in the mm size to the change procedure of micro-infiltrating carcinoma etc. between, so generally image check such as X ray, B ultrasonic is inapplicable.
Utilize the near infrared light technological development to go out mammary gland near-infrared somascope in recent years.It utilize hemoglobin in the blood of human body to the absorption of near infrared light than around its hetero-organization come imaging to differentiate greatly.The probe that existing near infrared light mammary gland tissue is surveyed usefulness have survey fl transmission light with survey retroreflection transmission light.The characteristics difference of these two kinds of technology is applicable to different occasions.
Retroreflection also can be described as back-reflection.Survey the retroreflection transmission light time, light source incidence point and back reflected laser bleeding point are usually located at the homonymy of mammary gland tissue.Light source and detector that the existing near infrared light mammary gland tissue of surveying retroreflection transmission light is surveyed the probe of usefulness are fixed, can not adjust the relative position of light source and detector during detection, and distance between the two is constant.Announced that as BrittonChance a kind of near infrared light mammary gland tissue surveys the structure of the probe of usefulness (" Academic Radiology ", Vol 12, No 8, August 2005), as shown in Figure 1.A plurality of photodetectors 2 be distributed in light source 1 around.The signal of telecommunication is collected and converted to the light that light source sends for subsequent treatment by detector after the mammary gland tissue transmission.The light source of this probe--distance is fixing nonadjustable between the-detector.
Near infrared light propagates into detector from light source path locus is a Fructus Musae shape in statistics, as shown in Figure 2.Photon is gone through and is repeatedly absorbed and scattering in this communication process.If distance is r between light source-detector, the middle part from tissue surface to Fructus Musae shape track is maximum average investigation depth so
Relative fixed between the light source of existing probe and the detector, distance is immutable, can't adjust the tissue of surveying different depth with convenient as required.The above-mentioned probe that is used to survey back reflected laser all exists some defectives.
Summary of the invention
The objective of the invention is to overcome the weak point of prior art, propose the probe that a kind of mammary gland tissue near infrared detection is used, have the detection efficient advantages of higher.
Described probe contains near-infrared light source and is used to receive the photodetector that is sent and passed through the mammary gland tissue near infrared light by described near-infrared light source, and the distance between described near infrared light light source and the described photodetector can be adjusted.It is characterized in that a displacement detector is arranged between described light source and the photodetector, described displacement detector is a slide wire resistance, the moved end of described slide wire resistance is connected on the shell of a described photodetector through lead-in wire, and a stiff end of this slide wire resistance is connected on the shell of described light source, along with described moved end moving on this slide wire resistance, thereby changed air line distance between described light source and the described photodetector.The moved end of described slide wire resistance is connected on the shell of described light source through lead-in wire, and a stiff end of this slide wire resistance is connected on the shell of described photodetector.Described photodetector and displacement detector are one separately at least simultaneously.Described displacement detector is a spring that has slide plate.
Distance between multi-wavelength near infrared light light source of the present invention and the described photodetector can be adjusted, so when test, do not need mobile probe, only need to regulate and change light source-detector distance between them, it is the tissue of detectable different depth, make exploration operation easier, detection efficient is improved.
Description of drawings
The sonde configuration sketch map that the existing a kind of mammary gland tissue near infrared from detecting of Fig. 1 is used.
Fig. 2 near infrared light propagates into the path locus sketch map of detector from light source.
A kind of embodiment sketch map of the probe that a kind of mammary gland tissue near infrared from detecting of Fig. 3 the present invention is used.
The another kind of embodiment sketch map of the probe that a kind of mammary gland tissue near infrared from detecting of Fig. 4 the present invention is used.
The specific embodiment
The invention is characterized in, a displacement detector is arranged between described light source and the photodetector, described displacement detector is a slide wire resistance, the moved end of described slide wire resistance is connected on the shell of a described photodetector through lead-in wire, and a stiff end of this slide wire resistance is connected on the shell of described light source, along with described moved end moving on this slide wire resistance, thereby changed air line distance between described light source and the described photodetector.
Operation principle of the present invention is: light source is sent out the light of different wave length successively, and the light incident of sending also enters mammary gland tissue, and overflow and organize in the transmission back in mammary gland tissue, receives the light that these pass through mammary gland tissue by being positioned at the outer photodetector of tissue.Photodetector converts the optical signal that detects to the corresponding signal of telecommunication, and sends the subsequent treatment unit to.Light source is sent out the light time of a wavelength, and detector obtains data, and it is right to have formed corresponding test data thus.The subsequent treatment unit is right according to test data, analyzes, exports under current light source-detector position relation, the optical characteristics of the position mammary gland tissue of surveying.Change distance between light source-detector then as required, repeat said process, to record the optical characteristics that light source-detector distance changes the back mammary gland tissue of being surveyed.
The present invention has designed the probe that a kind of mammary gland tissue near infrared detection is used, and implements 1 example and 3 is described in detail as follows in conjunction with the accompanying drawings:
Shown in Figure 3, in the probe of the embodiment of the invention, described near-infrared light source 1 is selected launched 730nm, 805nm that Epitex company produces and the three-wavelength light emitting diode L4*730/4*805/4*850-40Q96-I of 850nm for use, with OPT101 as described photodetector 2.Described slide wire resistance 3 adopts slide wire resistance.
Described slide wire resistance 3 is mechanically fastened at described detector 2 sides, and the moved end of described slide wire resistance 3 links to each other with described light source 1 by described line 4.The two ends of described line 4 are separately fixed on the moved end and described light source 1 of described slide wire resistance 3.
During test, at first controlled processing unit is controlled 1 wavelength X of described light source
1Light, described photodetector 2 sends the signal of telecommunication to the subsequent treatment unit after converting the optical signal of collecting to the signal of telecommunication, thereby obtains data Data
1Controlled processing unit is controlled described light source 1 and is sent out two wavelength X successively other then
2, λ
3Light, obtain corresponding data Data
2, Data
3According to data (Data
1, Data
2, Data
3), the current output resistance of described slide wire resistance 3 and the property calculation that near infrared light is propagated in mammary gland tissue, obtain related characteristics at mammary gland tissue that current location is surveyed.
Then as required, change the position of described light source 1.Along with the moved end of the described slide wire resistance 3 of described line 4 drives, the corresponding variation takes place in the output resistance of described slide wire resistance 3, and relative distance changes between described light source 1 and the described detector 2.Repeat aforementioned measuring process, the measurement data (Data behind the position that acquires change
1, Data
2, Data
3), and in the output resistance of the described slide wire resistance 3 of reposition, the property calculation of propagating in mammary gland tissue according near infrared light obtains the related characteristics at mammary gland tissue that reposition is surveyed again.
The present invention has designed the embodiment 2 of the probe that a kind of mammary gland tissue near infrared detection uses, and 4 is described in detail as follows in conjunction with the accompanying drawings:
Shown in Figure 4, select launched 730nm, 805nm that Epitex company produces and the three-wavelength light emitting diode L4*730/4*805/4*850-40Q96-I of 850nm for use at the near-infrared light source 1 described in the probe of the embodiment of the invention, with OPT101 as described photodetector 2.Described slide wire resistance 3 adopts slide wire resistance.
Described slide wire resistance 3 is fixed on described light source 1 side, and described slide wire resistance 3 links to each other with described detector 2 by described line 4.The two ends of described line 4 are separately fixed on described slide wire resistance 3 and the described detector 2.
During test, controlled processing unit is at first controlled 1 wavelength X of described light source
1Light, described photodetector 2 sends the signal of telecommunication to the subsequent treatment unit after converting the optical signal of collecting to the signal of telecommunication, thereby obtains data Data
1Controlled processing unit is controlled described light source 1 and is sent out two wavelength X successively other then
2, λ
3Light, obtain corresponding data Data
2, Data
3According to data (Data
1, Data
2, Data
3), the current output resistance of described slide wire resistance 3 and the property calculation that near infrared light is propagated in mammary gland tissue, obtain related characteristics at mammary gland tissue that current location is surveyed.
Then as required, change the position of described detector 2.Along with moving of described detector 2, described detector 2 is by the moved end of the described slide wire resistance 3 of described line 4 drives, and corresponding variation has taken place the output resistance of described slide wire resistance 3, and the distance between described light source 1 and the described detector 2 changes.Repeat aforementioned measuring process, the measurement data (Data behind the position that acquires change
1, Data
2, Data
3), and the current output resistance of described slide wire resistance 3, the property calculation of propagating in mammary gland tissue according near infrared light obtains the related characteristics at mammary gland tissue that reposition is surveyed again.
Claims (3)
1. probe that is used for the mammary gland tissue near infrared detection, contain a light source and a plurality of photodetector, it is characterized in that, near the light source place displacement detector is arranged between described light source and the photodetector, described displacement detector is a slide wire resistance, the moved end of described slide wire resistance is connected on the shell of a described photodetector through lead-in wire, and a stiff end of this slide wire resistance is connected on the shell of described light source, along with described moved end moving on this slide wire resistance, thereby changed air line distance between described light source and the described photodetector.
2. a kind of probe that near-infrared mammary tissue detects that is used for according to claim 1 is characterized in that, the identical and number of the number of described photodetector and displacement detector is one separately at least simultaneously.
3. a kind of probe that near-infrared mammary tissue detects that is used for according to claim 1 is characterized in that described displacement detector is a spring that has slide plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008102254454A CN101390749B (en) | 2008-10-31 | 2008-10-31 | Near infrared detection probe for mammary tissue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008102254454A CN101390749B (en) | 2008-10-31 | 2008-10-31 | Near infrared detection probe for mammary tissue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101390749A CN101390749A (en) | 2009-03-25 |
| CN101390749B true CN101390749B (en) | 2011-01-26 |
Family
ID=40491400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008102254454A Expired - Fee Related CN101390749B (en) | 2008-10-31 | 2008-10-31 | Near infrared detection probe for mammary tissue |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101390749B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101595434B1 (en) * | 2014-10-13 | 2016-02-19 | 한국생산기술연구원 | Apparatus and method for measuring the shape of stool |
| CN105997026B (en) * | 2016-06-13 | 2018-11-20 | 北京阿纽山医药科技有限公司 | A kind of intelligent health portable detection equipment |
| CN111134626B (en) * | 2020-01-13 | 2021-08-24 | 西安电子科技大学 | Flat mammary gland diffusion light tomography system without optical fiber |
| CN115211830A (en) * | 2021-04-15 | 2022-10-21 | 天津工业大学 | Near-infrared diffusion coherent spectrum local cerebral blood flow speckle imaging device and detection method |
-
2008
- 2008-10-31 CN CN2008102254454A patent/CN101390749B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101390749A (en) | 2009-03-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100353910C (en) | Non-invasive subject information imaging method and apparatus | |
| CN101002670B (en) | Method and apparatus for analyzing information of object, endoscope device | |
| CN110367941B (en) | Detection light fusion non-contact photoacoustic-optical coherence tomography dual-mode imaging system | |
| RU2571329C2 (en) | Device for receiving object information | |
| WO2012014390A2 (en) | Photoacoustic diagnostic apparatus | |
| CN100506150C (en) | Optical detection device and working method for tissue of living body | |
| WO1998050781A1 (en) | Method and apparatus for frequency encoded ultrasound-modulated optical tomography of dense turbid media | |
| CN101390749B (en) | Near infrared detection probe for mammary tissue | |
| US10674918B2 (en) | Near-infrared (NIR) optical scanner | |
| JPWO2011027548A1 (en) | Probe and image reconstruction method using the probe | |
| JP4327738B2 (en) | Biological light measurement device and biological light measurement method | |
| CN103654867A (en) | Imaging probe and imaging device with same | |
| JP6573732B2 (en) | Continuous monitoring of tumor hypoxia using near-infrared spectroscopy and tomography with a photonic mixer device | |
| US20210052210A1 (en) | Detection device and detection method for fusion of tactile sensing and optical tomography | |
| US9131844B2 (en) | Method and apparatus for tissue measurement position tracking and depth adjustment | |
| CN100536762C (en) | Probe for detecting the near-infrared mammary tissue | |
| CN110470646A (en) | Tumor tissues identifying system based on artificial intelligence and Raman spectrum | |
| CN105996999A (en) | Method and system for measuring depth resolution attenuation coefficient of sample based on OCT | |
| JP2017042643A (en) | Subject information acquisition apparatus and subject information acquisition method | |
| EP1809164B1 (en) | System and micro-catheter devices for medical imaging of the breast | |
| CN111012311A (en) | Handheld MEMS optical scanning imaging device | |
| CA2467407A1 (en) | Optical transillumination and reflectance spectroscopy to quantify disease risk | |
| JPWO2014042130A1 (en) | Scattered light measuring device | |
| CN201042433Y (en) | Living body tissue optical detector | |
| KR101420003B1 (en) | Integrated coherence tomography |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110126 Termination date: 20171031 |