CN101384289A

CN101384289A - Inhaler

Info

Publication number: CN101384289A
Application number: CNA2007800055214A
Authority: CN
Inventors: 拉尔夫·托梅斯
Original assignee: Transmission Equipment Co Ltd; Boehringer Ingelheim International GmbH
Current assignee: Transmission Equipment Co Ltd; Boehringer Ingelheim International GmbH
Priority date: 2006-02-20
Filing date: 2007-02-19
Publication date: 2009-03-11

Abstract

An inhaler is proposed for dispensing a powdered inhalation formulation from a blister strip with a multiplicity of blister pockets. The used part of the blister strip with emptied blister pockets is wound up by a watch spring or is pushed into a helical channel. A simple structure is thus permitted, wherein the used blister strip is separtaed from the still unused part.

Description

Inhaler

Technical field

The present invention relates to inhaler according to one preamble in the independent claims.

The present invention relates to a kind of inhaler that is used for discharging Powdered suction preparaton (Inhalationsformulierung) from the bubble bar (Blisterstreifen) of the bubble bag (Blistertaschen) that has a plurality of suction preparatons that respectively contain a dosage.

Background technology

GB 2 407 042 A disclose a kind of inhaler that has the bubble bar of coiling.The suction preparaton that will steep a dosage of bag when sucking respectively takes out and therefore with this bubble bag emptying.This can be for example realizes when the air-breathing suction by the patient in the following way, promptly produces the air flow by previous bubble bag that stung out or that otherwise open, makes the suction preparaton that is positioned at the bubble bag mix with air and discharge in the way you want.The bubble bag of emptying is discharged respectively and must be processed.

WO 2005/037353 A1 discloses similar inhaler, and the part (in the present invention, this part also abbreviates " having used part " as) of wherein steeping the bubble bag of having of bar of opened and/or emptying also is stored in the inhaler.This realizes in the following way, promptly makes the bubble bar form in having the twin-feed spiral that turns to movably endless belt.This structure is expensive and requires to make the bubble bar continue to move relative to higher power, and do not guarantee to steep the part of having used of bar and the optimal separation of untapped part still.Therefore, there is the demand of having used the organization plan of part for best storage.

Summary of the invention

Technical problem to be solved by this invention provides a kind of inhaler, this inhaler has been realized the best storage of using part for the bubble bag that has emptying of bubble bar, and/or will steep bar used with untapped bubble bag or partly separate to avoid or to reduce pollution.

Above technical problem is by solving according to one in the independent claims described inhaler.Favourable expansion is the theme of dependent claims.

A first aspect of the present invention is and will uses part to twine and/or be pulled in the spatial accommodation by spring force.This realizes by the clockwork spring that is arranged in the spatial accommodation that especially this clockwork spring is bonded on the free end that uses part of bubble bar.Therefore, realized using the very compact winding of part in simple and cheap mode.

Inhaler preferably has and is used to make the bubble bar progressively to continue the feedway that moves, so that the bubble bag can one after the other be suction emptying dosage separately.According to a kind of particularly preferred expansion, feedway is configured to preferably can only make the bubble bar can continue to move to next bubble bag by spring force with progressively discharging.

This has allowed the simplification of operation, because particularly in the inhaler of pure frame for movement, does not require that user makes the bubble bar move to the continuation of next one bubble bag from a bubble bag.But only need be for example to discharge the bubble bar relative to less power and on demand very short the move release or the discharging that can realize, it is mobile until next one bubble bag to make that the bubble bar continues by spring force.

According to the second aspect that can independently realize of the present invention, the part of use of bubble bar is not drawn into spatial accommodation, but preferably only pushes this spatial accommodation.The obvious simplification that this has allowed frame for movement has particularly reduced needed part.

Spatial accommodation preferably forms passage, and passage is especially with spirally or spiral extension.Passage preferably has little channel width, and this channel width is corresponding with the radial thickness that uses part of bubble bar at least basically.Therefore realized using the mandatory guidance of part in simple mode.Especially, if will use part to push in the passage, then it is just by spiral type or spirally ground " winding ".

Especially preferred is being set for the feedway of the inhaler that the bubble bar continue to move to be constituted fully and as follows as unique driver: make to change the still untapped part that feedway is sent into the bubble bag that has as yet not emptying of bubble bar on the one hand, on the other hand then still untapped part be pushed in spatial accommodation or the passage.Feedway preferably is arranged between the memorizer and spatial accommodation that are used for untapped part still of inhaler.

According to the third aspect that also can independently realize of the present invention, inhaler have other device be used to flatten emptying the bubble bag.This size that spatial accommodation requires of using part that is used in the bubble bar can obviously reduce, because the bubble bag of emptying has occupied obviously littler space after flattening.Therefore, inhaler is constructed especially compactly.

Especially preferred is that feedway and storing apparatus can side by side or one after the other be handled, particularly by common operating element, and for example can be by the pivot manoeuvre of bar.Especially formed the attachment device of feedway.

According to the fourth aspect that can independently realize of the present invention, storing apparatus is constructed so that the part of using of bubble bar is twined or crooked on the direction that the still untapped part (the particularly part in memorizer) with the bubble bar is wound or crooked direction is identical.This has allowed again compact especially and therefore space-saving the bubble bar have been used the winding or the bending of part, makes the size of spatial accommodation and therefore the physical dimension of inhaler is minimized.

According to favourable expansion, the winding plane of not using part of bubble bar is positioned at identical plane with the winding plane of using part of bubble bar.In this case, the adjacent layout of memorizer and spatial accommodation.This has especially allowed the structure of a kind of especially flat of minimizing of structure height and inhaler.

According to a kind of optional form of implementation, do not use the winding plane of part and used the winding plane of part overlapping.In this case, memorizer and spatial accommodation are arranged overlappingly.What this had allowed especially that the area of inhaler extends minimizes.

According to the 5th aspect that can independently realize of the present invention, be used to steep bar and used the spatial accommodation of part and be used to steep that memorizer that bar do not use part is separated from each other or separated from one another, make that particularly may still exist the residue (at least when normal use of inhaler) that sucks preparaton not arrive the bubble bar does not use part and can not for example partly be discharged to the outside in undesirable mode in the not use of bubble bar in the bubble bag of opened and emptying.Otherwise may cause inaccurate dosage, but, this can be avoided by the separation according to suggestion of the present invention.

Description of drawings

Accessory rights requires and is following to having provided other aspect of the present invention, feature, characteristics and advantage in the description of preferred implementing form in conjunction with the accompanying drawings, in the accompanying drawings:

Fig. 1 shows the sketch map according to the inhaler of being advised of first form of implementation, and inhaler is in opened state, and has the bubble bar that uses fully;

Fig. 2 shows the sketch map according to the inhaler of being advised of second form of implementation, and inhaler is in opened state, has still untapped to a great extent bubble bar;

Fig. 3 shows the sketch map according to the inhaler of being advised of the 3rd form of implementation, and this inhaler is similar to first kind of inhaler very much; With

Fig. 4 shows the sketch map according to the inhaler of being advised of the 4th form of implementation, and this inhaler is similar to second kind of inhaler very much.

In the accompanying drawings, used identical Reference numeral, also omitted multiple description for same or similar part.Especially when identical or corresponding advantage and characteristics are provided.

The specific embodiment

Fig. 1 shows according to one of the inhaler of being advised 1 of first form of implementation very schematic figure, does not just have top cover or covering at the state of cutting open or opening.

Inhaler 1 is used for being preferably pulverous suction preparaton from bubble bar 2 discharges that have a plurality of bubble bags 3, and each bubble bag 3 directly contains the especially loose suction preparaton of a dosage.Form the powder 4 for example expression in bubble bag 3 in Fig. 1 that sucks preparaton.For sucking and especially when sucking, preferably respectively the suction preparaton of a dosage is taken out in bubble bag 3.

Bubble bar 2 preferably constitutes zonal.Preferably, bubble bar 2 is configured to have the end, does not promptly form the band of annular or sealing.

Inhaler 1 preferably has the still untapped bubble bar 2 of memorizer 5 with the bubble bag 3 that is used to have as yet not emptying.Especially, bubble bar 3 is reeled or is wrapped in the memorizer 5.In illustrated embodiment, memorizer 5 is constructed so that bubble bar 2 can be shifted out as far as possible gently or pull out.Especially, in illustrated embodiment, do not provide separates walls or inner guide, but memorizer 5 only passes through preferred sidewall and planar side (Flachseiten) limited boundary that connects at this.The coiling of untapped bubble bar 2 or crooked plane (being the bubble bar 2 in the memorizer 5) at this corresponding to tag plane or parallel plane.

In illustrated embodiment, bubble bar 2 directly is contained in the memorizer 5.Yet, alternatively also can be inserted in inhaler 1 or the memorizer 5 having the box that steeps bar 2, container, drum etc.

Inhaler has suction nozzle 6 to be used for unshowned user.Preferably utilize and thrust the indivedual emptyings of element A realization bubble bag 3 by withdrawing device 18.

Withdrawing device 18 only schematically illustrates at this, and preferably is arranged as contiguous suction nozzle 6.

Can open each bubble bag 3 by withdrawing device 18, for example can thrust and maybe can cut bubble bag 3.Especially, can open each bubble bag 3 from the outside, especially it be thrust or cuts with thrusting element A by withdrawing device 18.

Preferably, each the bubble bag of opening 3 emptying when sucking by sucking.Therefore the air flow L of surrounding air is inhaled into, and by withdrawing device 18 the bubble bag of opening 3 is conducted through, thereby the surrounding air that makes the suction preparaton of emitting and suction is as particulate cloud 17 discharges.

Inhaler 1 has and is used to make bubble bar 2 preferably to move the feedway 7 that bubble bag 3 ground progressively continue to move at every turn, so that bubble bag 3 can be supplied in succession withdrawing device 18 to be used to discharge and suck dosage separately.

Bubble bar 2 in feedway 7 preferably to multi-steering 90 degree.This has supported desirable easy proximity.

Feedway 7 has driving wheel 8 in illustrated embodiment, but driving wheel 8 for example is bonded between the bubble bag 3 and so form closure ground (formschluessig) supply bubble bar 2.Feedway 7 preferred manual are handled.Possible CONSTRUCTED SPECIFICATION provides according to the description to second form of implementation.

Inhaler 1 has the storing apparatus 9 that especially has spatial accommodation 10 to hold or to store the use part of for example steeping bar 2.

Storing apparatus 9 is constructed so that in first form of implementation bubble bar 2 can push in the spatial accommodation 10 in (promptly after each bubble bag 3 emptyings) after the use, particularly wherein steeps bar 2 or has used part to hold in the mode with compactness that limits.For this reason, spatial accommodation 10 for example can provide unshowned guiding piece etc.But especially preferred is that spatial accommodation 10 is provided with and bubble bar 2 can be pushed passage wherein or is configured to passage.

Fig. 1 shows at the repeatedly use of bubble bag 3 and the inhaler 1 after the corresponding emptying.The bubble bar 2 in illustrated state from memorizer 5 fully send and at least very most of on hold by storing apparatus 9 and spatial accommodation 10 thereof, in illustrated embodiment, promptly be pushed in the passage.

Passage preferably has as far as possible little channel width, and this channel width corresponds essentially to the radial thickness that uses part of bubble bar 2 at least.

Passage is preferably at least basically with spirally or spiral extension.Yet other form also is fine in principle, and for example passage can extend with indentation and/or in other planes.

Storing apparatus 9 and particularly inhaler 1 are constructed so that preferably the part of using of bubble bar 2 holds on the direction that the still untapped part of the bubble bag 3 that has as yet not emptying with bubble bar 2 is being wound in the inhaler 1 (particularly at memorizer 5) or crooked direction is identical, particularly twine or crooked.Consistent coiling or bending direction also are applicable to other zone, wherein steep bar 2 and be directed in inhaler 1 in this zone, promptly for example guide to spatial accommodation 10 from memorizer 5, promptly are usually used for steeping bar 2.Because the bending or the coiling direction of unanimity of bubble bar 2, will steep bar 2 (promptly having used part) bending or reel narrowly as far as possible and compact easilier, construct as far as possible for a short time spatial accommodation 10 and conserve space promptly easilier.In addition, must be when bubble bar 2 with the radius bend determined and when crooked in the opposite direction in advance, realize obviously littler supply power and therefore realized the easier operability of inhaler 1.

Feedway 7 is sized to fully firm in illustrated embodiment, makes the part of use of bubble bar 2 to push in the passage.Especially, therefore steeping bar 2 only continues to move or move forward by feedway.Especially, inhaler 1 only has unique feedway 7.This has allowed the simple of the inhaler 1 that formed by few parts and therefore also cheap structure.

Feedway 7 preferably is arranged between memorizer 5 and the storing apparatus 9, particularly between withdrawing device and spatial accommodation 10, promptly after emptying bubble bag 3.

Spatial accommodation 10 preferably separates with memorizer 5, especially separates by the midfeather 11 that connects in illustrated embodiment.The residue that can prevent in this way or make possible suction preparaton at least from bubble bag 3 emptying and that open deviate from and in the outside accumulates in the zone of not using part on the bubble bar 2 (the bubble bag 3 that promptly also remains full of) may reduce to minimum.Separately the preventing or making at least of spatial accommodation 10 owing to may polluting of causing of described residue or dosage mistake reduce to minimum.

Following according to detailed second form of implementation of explaining the inhaler 1 of being advised of Fig. 2, this second form of implementation is corresponding with Fig. 1 at least basically.For avoiding repetition, only explain the basic difference of second form of implementation and first form of implementation below.And as one man or replenish ground effectively hereto for general description and interpretation of the present invention to the description and interpretation of first form of implementation.

In second form of implementation, inhaler 1 and storing apparatus 9 are constructed so that the use part of bubble bar 2 twines and/or draw in the spatial accommodation 10 by spring force.Feedway 9 preferably has spring for this reason, and particularly clockwork spring 12, and its state with tensioning in Fig. 2 only schematically illustrates.

In illustrated embodiment, spring is arranged in the storing apparatus 10 and the preferred bubble bar 2 that engages has used free end partly.For example, spring 2 hangs on the end regions of bubble bar 2.

Feedway 7 continues to supply with forward bubble bar 2 more, and then (the using) of the bubble bar 2 that extends in spatial accommodation 10 part is long more, and this part is twined accordingly by clockwork spring 12 then.Yet, also be possible in this other structure solution with same or similar effect.

According to particularly advantageous expansion, the tension force of spring or pulling force (being spring force) are enough high, so that bubble bar 2 moves forward and pulls out from memorizer 5, promptly also twine bubble bar 2 in case of necessity according to structure.In this case, feedway 7 is constructed so that preferably bubble bar 2 can progressively discharge and each preferably only continues to move to next bubble bag 3 by spring force.This has realized the simple especially manipulation and the operation of inhaler 1, for example carries out release or discharge by handling unshowned button because only need to ask by unshowned user.Therefore, the bubble bar 2 that especially can get rid of in inappropriate manipulation is supplied with to the incomplete continuation of next one bubble bag 3 from a bubble bag 3.

But, feedway 7 preferably is configured to make operating element (particularly action bars 13) to be pivoted so that driving wheel 8 progressively continues rotation and therefore will steep bar 2 and correspondingly continue to supply with a step by unshowned operator in illustrated embodiment.Driving wheel 8 and feedway 7 preferably have idle running and corresponding spin locking, even make driving wheel 8 also can only rotate with the step-length of hope in one direction and especially only in the way you want in reciprocal the pivot and when action bars 13 takes place not exclusively to pivot.

In second form of implementation, inhaler 1 preferably have flatten emptying the attachment device 14 of bubble bag 3.Attachment device 14 allows to flatten the bubble bag 3 of emptying before relevant the holding of spatial accommodation 10.Flatten especially in feedway 7 or supply roll 8 backs and before spatial accommodation 10, carry out.

The flattening of the bubble bag 3 of emptying has caused being used to steeping the obvious littler space requirement that uses part of bar 2, make therefore spatial accommodation 3 and so inhaler 1 can construct obviously forr a short time and compacter.

Advantageously attachment device 14 connects with feedway 7 or is formed by it especially.Especially, the preferred and then step after the continuation of bubble bar 2 is supplied with of the flattening of the bubble bag 3 of emptying carries out, promptly is used for the bubble bag 3 that the next one is full of.Particularly preferably be fully attachment device 14 and feedway 7 operating element, particularly link with action bars 13.

In illustrated embodiment, attachment device 14 forms by the prolongation 15 of action bars 13, this prolongation 15 causes the flattening to the bubble bag 3 of emptying when the pivoting fully of action bars 13, this realizes by each bubble bag 3 is clamped between the fixed opposed abutment face 16 at the prolongation 15 that is provided with corresponding abutment face with in illustrated embodiment.Because the conversion of corresponding bar, can therefore realize the flattening of effectively bubble bag 3 to emptying.Therefore, compare with the bubble bag 3 that does not flatten, bubble bar 2 can obviously be twined more compactly by storing apparatus 9 (being clockwork spring 12 in illustrated embodiment).

Schematically showing the suction preparaton at Fig. 2 medium cloud 17 can discharge by inhaler 1 when atomizing when sucking in other words.

Third and fourth form of implementation has been shown in Fig. 3 and Fig. 4, and they are carried by pressed gas or air from the suction preparaton in each bubble bag 3 in third and fourth form of implementation to a great extent corresponding to first and second forms of implementation.This for example is an active inhaler 1; Be preferably pulverous but also be that the suction preparaton of liquid is atomized on one's own initiative or discharges in case of necessity, and by when sucking because the air flow of air-breathing generation atomizing or discharge.

Inhaler 1 and withdrawing device 18 have device 19 so that the gas under the pressure to be provided for this reason.At this, this device can for example be to be used to compress and/or the gas reservoir of liquid gas, but or for example is the air pump of manual control.

Withdrawing device 18 for example has schematically illustrated inlet tube 20, with can be with the gas under the pressure (particularly air) from installing the 19 bubble bags of supplying with to separately of opening 3.Gas under the pressure is directed in the bubble bag 3, carries out and atomizes will suck preparaton, particularly forms by sucking the mixture that can suck that preparaton and gas or air form and so generating particulate cloud 17.Yet, also be fine in this other structure solution, suction preparaton from the bubble bag of opening 3 especially can at first be supplied with in flow path where necessary, for example by supplies such as gravity, vibration, so that carry out by the gas under the pressure subsequently and atomize.

The one feature of one form of implementation and variant and aspect be combination in any or use in other inhaler 1 mutually also.

Claims

1. one kind is used for discharging the inhaler (1) that is preferably Powdered suction preparaton from the bubble bar (2) that has a plurality of bubble bags (3), and described bubble bag contains the suction preparaton of a dosage respectively, and this inhaler (1) has

Be used for progressively continuing to move the feedway (7) of described bubble bar (2),

Be used for the described bubble bag of individually emptying (3) device (18,19) and

Storing apparatus (9), this storing apparatus (9) have the spatial accommodation (10) that the bubble bar (2) that is used to hold the described bubble bag (3) that especially has emptying has used part,

It is characterized in that:

Described feedway (7) and/or described storing apparatus (9) are constructed to make the described part of having used to be pushed in the described storing apparatus (10) when continuation is mobile.

2. inhaler according to claim 1 is characterized in that: described spatial accommodation is constructed to passage.

3. inhaler according to claim 2 is characterized in that: the channel width of described passage is corresponding with the described radial thickness of part that used at least basically.

4. according to claim 2 or 3 described inhalers, it is characterized in that: the trend of described passage is spirally or spiral type.

5. according to each described inhaler in the claim 1 to 4, it is characterized in that: described feedway (7) is between the memorizer (5) that is bonded on described spatial accommodation (10) and described inhaler (1) on the described bubble bar (2), and the bubble bar (2) that this memorizer is used to have as yet the described bubble bag (3) of not emptying does not use part.

6. according to each described inhaler in the claim 1 to 5, it is characterized in that: described feedway (7) has formed the unique driver that is used for moving described bubble bar (2).

7. one kind is used for discharging the inhaler (1) that is preferably Powdered suction preparaton from the bubble bar (2) that has a plurality of bubble bags (3), and described bubble bag contains the suction preparaton of a dosage respectively, and described inhaler has

It is characterized in that:

Described storing apparatus (9) is constructed to make the described part of having used to twine and/or be pulled in the described spatial accommodation (10) by spring force.

8. inhaler according to claim 7 is characterized in that: described storing apparatus (9) has spring, particularly has a clockwork spring (12).

9. inhaler according to claim 8 is characterized in that: described spring is arranged in the described spatial accommodation (10).

10. it is characterized in that according to Claim 8 or 9 described inhalers: described spring is bonded on the described free end that has used part.

11. according to each described inhaler in the claim 7 to 10, it is characterized in that: described feedway (7) is constructed so that described bubble bar (2) can progressively be discharged and preferably can only continues step by step to move by spring force respectively.

12. one kind is used for discharging the inhaler (1) that is preferably Powdered suction preparaton from the bubble bar (2) that has a plurality of bubble bags (3), each described inhaler (1) in particularly requiring according to aforesaid right, described bubble bag contains the suction preparaton dosage of a dosage respectively, and described inhaler has

It is characterized in that:

Described inhaler (1) has the attachment device (14) of the described bubble bag (3) that is used to flatten emptying.

13. inhaler according to claim 12 is characterized in that: described attachment device (14) allows to be contained in described bubble bag (3) flattening of emptying before in the described spatial accommodation (10) separately at the described bag (3) that steeps of emptying.

14. according to claim 12 or 13 described inhalers, it is characterized in that: described attachment device (14) and described feedway (17) can particularly preferably be handled by the pivot of bar (13) in succession or side by side by common operating element, and particularly wherein said attachment device (14) forms or is integrated in the described feedway (7) by described feedway (7).

15. one kind is used for discharging the inhaler (1) that is preferably Powdered suction preparaton from the bubble bar (2) that has a plurality of bubble bags (3), each described inhaler (1) in particularly requiring according to aforesaid right, described bubble bag contains the suction preparaton of a dosage respectively, and this inhaler has

The bubble bar (2) that is used to hold the described bubble bag (3) that especially has emptying has used the storing apparatus (9) of part,

It is characterized in that:

Described storing apparatus (9) be constructed to make described used part twine inhaler (1) in the not use part of the bubble bag (3) that has as yet not emptying of described bubble bar (2) or direction that crooked direction is identical on twine or bending.

16. inhaler according to claim 15 is characterized in that: the described winding plane of part of not using is positioned at identical plane with the described winding plane of part of having used.

17. inhaler according to claim 15 is characterized in that: the winding plane of described use part and the described winding plane of part of having used are overlapping.

18. one kind is used for discharging the inhaler (1) that is preferably Powdered suction preparaton from the bubble bar (2) that has a plurality of bubble bags (3), particularly according to the described inhaler (1) of aforementioned claim, described bubble bag contains the suction preparaton of a dosage respectively, and this inhaler has

The memorizer (5) of still untapped described bubble bar (2) that is used to have as yet the described bubble bag (3) of not emptying,

It is characterized in that:

Described spatial accommodation (10) separates with described memorizer (5).

19. according to each described inhaler in the aforesaid right requirement, it is characterized in that: described inhaler (1) is constructed to portable inhaler.

20. according to each described inhaler in the aforesaid right requirement, it is characterized in that: the described device (18,19) that is used for individually emptying bubble bag (3) is configured to by the gas under the pressure, especially by compressed air discharge dosage separately.

21. according to each described inhaler in the aforesaid right requirement, it is characterized in that: described bubble bag (3) can be individually in succession from external opening, therefore especially by air-breathing when sucking the air flow (L) in the draws ambient air, form particulate cloud (17) with general's dosage separately with surrounding air.

22. according to each described inhaler in the aforesaid right requirement, it is characterized in that: described inhaler (1) is configured to hold the bubble bar (2) with end.

23. according to each described inhaler in the aforesaid right requirement, it is characterized in that: described feedway (7) makes described bubble bar (2) be diverted to many 90 degree.