CN101366686A - Application of compound carboxymethyl inulin - Google Patents
Application of compound carboxymethyl inulin Download PDFInfo
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- CN101366686A CN101366686A CNA2008101401812A CN200810140181A CN101366686A CN 101366686 A CN101366686 A CN 101366686A CN A2008101401812 A CNA2008101401812 A CN A2008101401812A CN 200810140181 A CN200810140181 A CN 200810140181A CN 101366686 A CN101366686 A CN 101366686A
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- inulin
- carboxymethyl
- moisture
- carboxymethyl inulin
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Abstract
The invention relates to the daily chemical field and a medicine industry, in particular to application of carboxymethyl synanthrin compound. The carboxymethyl synanthrin compound can be used as a moisture absorption and retention agent. The carboxymethyl synanthrin has strong capacity of moisture absorption and retention, can be used as a substitute for expensive hyaluronic acid in a moisture retention agent of cosmetic, and substantially reduces cost.
Description
Technical field
The present invention relates to household chemicals field and pharmaceuticals industry, specifically is a kind of application of compound carboxymethyl inulin.
Background technology
Moisture-absorption humectant is an indispensable important component in the cosmetics, and it plays an important role in cosmetics: (one) improves the xerosis cutis state: moisture-absorption humectant can obviously improve the water content of skin, increases skin elasticity.(2) prevention skin damage and the reparation of promotion damaged skin.The wetting agent kind is a lot, wherein derives from the wetting agent of organism---and (Hyaluronic acid HA) is the splendid wetting agent of a kind of performance to hyaluronic acid.HA does not have any zest to human body skin, is applied in the cosmetics, and skin is had the effect of moistening, and can make skin high resilience, smooth, delay skin aging.Hyaluronic source one is to extract from animal tissue, the 2nd, from microbial fermentation solution, extract.But hyaluronic acid mainly is distributed in the animal tissues such as connective tissue, umbilical cord, human serum, cockscomb, knuckle synovia, cartilage, vitreum, and raw material is limited, be difficult to collection and processing, cost of material height, content are low, separation process complexity etc.And utilize the fermentative Production hyaluronic acid only to be in research and starting stage at present.Owing to above reason makes hyaluronic acid can't satisfy market demand.For this reason, people constantly research and develop the product similar to its effect.
Inulin (Inulin) is called inulin again and (referring to Fig. 1 a), is a kind of biological polyoses, mainly is present in the body of plant that as Jerusalem artichoke, Herba Cichorii, tragopogon pratensis l., Dahlia Pinnata Cav. tuber etc., wherein Jerusalem artichoke is the primary raw material source that inulin is produced.Jerusalem artichoke is commonly called as Jerusalem artichoke, Jerusalem artichoke, China's various places common cultivated, and its tuber is rich in inulin, and total inulin content is generally 14～17%, and the source is abundant, and cost is lower.The inulin hygroscopicity is strong, has the ability in conjunction with Free water, thereby the wetting agent control food humidity that can be used as food extends the shelf life.Structure and the character special according to inulin itself, with its object as chemical modification, introducing has the moisture-absorbing moisture-keeping active group on its active hydroxyl, enlarges the application of inulin in cosmetics.
Summary of the invention
The purpose of this invention is to provide a kind of compound carboxymethyl inulin, can be used as with low cost, moisture-absorption humectant efficiently.
For achieving the above object, the technical solution adopted in the present invention is:
The application of compound carboxymethyl inulin, described compound carboxymethyl inulin can be used as moisture-absorption humectant.Wherein carboxymethyl inulin is according to meticulous and specialty chemicals, and on October 6th, 2007, the 15th rolled up for the 19th phase; Author: Sun Ting, Lv Rongwen, Zhang Hongbing, the start-stop page number: 10-13, preparation.
With carboxymethyl inulin place with the saturated ammonium sulfate aqueous solution keep relative humidity (RH) be 81% and saturated aqueous sodium carbonate to keep relative humidity be in 43% the exsiccator, measure its moisture pick-up properties, at RH is under 43% condition, 24, after 48 hours, the hydroscopicity of carboxymethyl inulin is respectively 28.69% and 42.33%; At RH is under 81% condition, and after 24,48 hours, the hydroscopicity of carboxymethyl inulin is respectively 25.06% and 35.59%. With water content be 10% carboxymethyl inulin place relative humidity be 43%, 81% and silica gel drier in, measure its performance of keeping humidity, be under 43% condition at RH, after 24,48 hours, the rate of preserving moisture of carboxymethyl inulin is respectively 273.89% and 373.40%; At RH is under 81% condition, and after 24,48 hours, the rate of preserving moisture of carboxymethyl inulin is respectively 221.17% and 252.51%; In silica gel drier, after 24,48 hours, the rate of preserving moisture of carboxymethyl inulin is respectively 38.59% and 28.36%.
The advantage that the present invention had: carboxymethyl inulin of the present invention can be used as moisture-absorption humectant.Because inulin itself is a macromolecular structure, many hydroxy functional groups are arranged, and carboxymethyl inulin has been introduced the carboxymethyl hydrophilic functional groups on the inulin molecule, therefore, carboxymethyl inulin not only can absorb a large amount of hydrones, and can discharge hydrone lentamente, so its moisture-absorbing moisture-keeping activity will be higher than inulin, and its moisture absorption activity is higher than hyaluronic acid 20-30%, and its activity of preserving moisture is higher than hyaluronic acid 30-70%.And the raw material sources that are used for producing carboxymethyl inulin are extensive, and low production cost so just makes its production cost as moisture-absorption humectant is significantly reduced.
Figure of description
Fig. 1 is inulin and carboxymethyl inulin structural formula sketch map, wherein (inulin a and carboxymethyl inulin b structural formula sketch map wherein, n=2-70; R=-CH
2COO
-).
Fig. 2 is the infrared spectrogram of inulin.
Fig. 3 is the infrared spectrogram of the carboxymethyl inulin of the present invention's employing.
The specific embodiment
The preparation of carboxymethyl inulin:
Take by weighing 3g inulin (referring to Fig. 1 a and Fig. 2), add the 30mL isopropyl alcohol, stirring at room was divided 6 times and is added 10molL after 20 minutes
-1NaOH solution, each 1.26mL continues to stir 45 minutes, and the 3.6g chloroacetic acid is dissolved in the isopropyl alcohol, gradation adds in the reactant liquor, continues reaction 3 hours under the room temperature.After reaction finished, sucking filtration precipitated 3-4 time vacuum lyophilization with methanol wash.Products therefrom is faint yellow pulverulent solids soluble in water.(referring to Fig. 1 b and Fig. 3) by inulin a shown in Figure 1 and carboxymethyl inulin b structural formula sketch map wherein, n=2-70; R=-CH
2COO.
Described compound carboxymethyl inulin is as the application of moisture-absorption humectant:
1) moisture absorption determination of activity: carboxymethyl inulin is ground to form fine powder, vacuum lyophilization is to constant weight, accurately take by weighing 0.5g, place respectively with the saturated ammonium sulfate aqueous solution keep relative humidity (RH) be 81% and saturated aqueous sodium carbonate to keep relative humidity be moisture absorption in 43% the exsiccator, each weighing of 24h, 48h once, parallel two parts average (referring to table 1).Matched group is respectively inulin, hyaluronic acid and carboxymethyl chitosan.Hydroscopicity (%)=(W
1-W
0) * 100/W
0, W
0And W
1Be respectively carboxymethyl inulin and place forward and backward quality (g).
2) determination of activity of preserving moisture: with water content be 10% sample place relative humidity be 43%, 81% and silica gel drier in each weighing of 24h, 48h once, parallel two parts average (referring to table 2).
Moisture survival rate (%)=100 * H
n/ H
0, H
0, H
nBe respectively the quality (g) of moisture before and after placing.
Three groups of matched groups, inulin, hyaluronic acid and carboxymethyl chitosan are also surveyed hydroscopicity and moisture survival rate by same procedure.
Experimental result: the moisture absorption of carboxymethyl inulin is active and preserve moisture activity respectively shown in table 1, table 2, and its moisture pick-up properties and performance of keeping humidity all are better than inulin and hyaluronic acid.
The hydroscopicity of table 1 carboxymethyl inulin (%)
The rate of preserving moisture (%) of table 2 carboxymethyl inulin
Claims (1)
1. the application of a compound carboxymethyl inulin is characterized in that: described compound carboxymethyl inulin can be used as moisture-absorption humectant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810140181A CN100594877C (en) | 2008-09-05 | 2008-09-05 | Application of carboxymethyl inulin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810140181A CN100594877C (en) | 2008-09-05 | 2008-09-05 | Application of carboxymethyl inulin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101366686A true CN101366686A (en) | 2009-02-18 |
| CN100594877C CN100594877C (en) | 2010-03-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810140181A Expired - Fee Related CN100594877C (en) | 2008-09-05 | 2008-09-05 | Application of carboxymethyl inulin |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101824102A (en) * | 2010-04-27 | 2010-09-08 | 中国科学院烟台海岸带研究所 | N-(ethylamino) inulin and preparation and application thereof |
| WO2013087665A3 (en) * | 2011-12-12 | 2013-08-08 | Dequest Ag | Composition comprising a carboxylated fructan for epidermis hydratation |
| FR3003166A1 (en) * | 2013-03-12 | 2014-09-19 | Limousine D Applic Biolog Soc Ind | USE OF FRUCTANES OF TARAXACUM OFFICINALE TO COMBAT THE EFFECTS OF POLLUTION OF THE SKIN |
| CN109431914A (en) * | 2018-12-27 | 2019-03-08 | 湖南御家化妆品制造有限公司 | Scalp care composition and application thereof |
| CN109762078A (en) * | 2019-04-09 | 2019-05-17 | 中国科学院烟台海岸带研究所 | A kind of hydroxypropyltrimethylammonium chloride chitosan-carboxylated polysaccharide complex salt and preparation method and application |
-
2008
- 2008-09-05 CN CN200810140181A patent/CN100594877C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101824102A (en) * | 2010-04-27 | 2010-09-08 | 中国科学院烟台海岸带研究所 | N-(ethylamino) inulin and preparation and application thereof |
| CN101824102B (en) * | 2010-04-27 | 2014-04-16 | 中国科学院烟台海岸带研究所 | N-(ethylamino) inulin and preparation and application thereof |
| WO2013087665A3 (en) * | 2011-12-12 | 2013-08-08 | Dequest Ag | Composition comprising a carboxylated fructan for epidermis hydratation |
| FR3003166A1 (en) * | 2013-03-12 | 2014-09-19 | Limousine D Applic Biolog Soc Ind | USE OF FRUCTANES OF TARAXACUM OFFICINALE TO COMBAT THE EFFECTS OF POLLUTION OF THE SKIN |
| CN109431914A (en) * | 2018-12-27 | 2019-03-08 | 湖南御家化妆品制造有限公司 | Scalp care composition and application thereof |
| CN109762078A (en) * | 2019-04-09 | 2019-05-17 | 中国科学院烟台海岸带研究所 | A kind of hydroxypropyltrimethylammonium chloride chitosan-carboxylated polysaccharide complex salt and preparation method and application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100594877C (en) | 2010-03-24 |
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