CN101348463A - Synthetic method of argatroban and intermediate thereof - Google Patents
Synthetic method of argatroban and intermediate thereof Download PDFInfo
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- CN101348463A CN101348463A CNA2008100841497A CN200810084149A CN101348463A CN 101348463 A CN101348463 A CN 101348463A CN A2008100841497 A CNA2008100841497 A CN A2008100841497A CN 200810084149 A CN200810084149 A CN 200810084149A CN 101348463 A CN101348463 A CN 101348463A
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Priority Applications (1)
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CN2008100841497A CN101348463B (en) | 2007-12-25 | 2008-03-27 | Synthetic method of argatroban and intermediate thereof |
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CN200710060132.3 | 2007-12-25 | ||
CN200710060132 | 2007-12-25 | ||
CN2008100841497A CN101348463B (en) | 2007-12-25 | 2008-03-27 | Synthetic method of argatroban and intermediate thereof |
Publications (2)
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CN101348463A true CN101348463A (en) | 2009-01-21 |
CN101348463B CN101348463B (en) | 2010-06-02 |
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CN2008100841497A Active CN101348463B (en) | 2007-12-25 | 2008-03-27 | Synthetic method of argatroban and intermediate thereof |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101560244B (en) * | 2009-04-21 | 2011-05-25 | 深圳翰宇药业股份有限公司 | New method for synthesizing argatroban by combining solid phase method and liquid phase method |
CN102558047A (en) * | 2011-12-14 | 2012-07-11 | 天津药物研究院药业有限责任公司 | Method for preparing 3-methylquinoline |
CN101519429B (en) * | 2009-03-31 | 2012-07-25 | 深圳翰宇药业股份有限公司 | Solid phase method for synchronizing Argatroban |
CN104059125A (en) * | 2014-06-20 | 2014-09-24 | 天津市亨必达化学合成物有限公司 | Method for preparing argatroban intermediate amidate |
CN105218627A (en) * | 2015-11-19 | 2016-01-06 | 天津市亨必达化学合成物有限公司 | A kind of purification process of argatroban chiral intermediate hydrolyzate |
CN103936821B (en) * | 2013-01-18 | 2016-04-13 | 江苏奥赛康药业股份有限公司 | A kind of preparation method of optical purity argatroban |
CN111793022A (en) * | 2020-04-27 | 2020-10-20 | 滁州拜奥生物科技有限公司 | Preparation method of 3-methylquinoline |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100465161C (en) * | 2006-11-10 | 2009-03-04 | 天津市炜杰科技有限公司 | Process for preparing argatroban intermediates |
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2008
- 2008-03-27 CN CN2008100841497A patent/CN101348463B/en active Active
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101519429B (en) * | 2009-03-31 | 2012-07-25 | 深圳翰宇药业股份有限公司 | Solid phase method for synchronizing Argatroban |
CN101560244B (en) * | 2009-04-21 | 2011-05-25 | 深圳翰宇药业股份有限公司 | New method for synthesizing argatroban by combining solid phase method and liquid phase method |
CN102558047A (en) * | 2011-12-14 | 2012-07-11 | 天津药物研究院药业有限责任公司 | Method for preparing 3-methylquinoline |
CN102558047B (en) * | 2011-12-14 | 2013-10-30 | 天津药物研究院药业有限责任公司 | Method for preparing 3-methylquinoline |
CN103936821B (en) * | 2013-01-18 | 2016-04-13 | 江苏奥赛康药业股份有限公司 | A kind of preparation method of optical purity argatroban |
CN104059125A (en) * | 2014-06-20 | 2014-09-24 | 天津市亨必达化学合成物有限公司 | Method for preparing argatroban intermediate amidate |
CN105218627A (en) * | 2015-11-19 | 2016-01-06 | 天津市亨必达化学合成物有限公司 | A kind of purification process of argatroban chiral intermediate hydrolyzate |
CN111793022A (en) * | 2020-04-27 | 2020-10-20 | 滁州拜奥生物科技有限公司 | Preparation method of 3-methylquinoline |
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Publication number | Publication date |
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CN101348463B (en) | 2010-06-02 |
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Owner name: TIANJIN MEDICINE RESEARCH INSTITUTE OF PHARMACEUTI Free format text: FORMER NAME: TAIPU MEDICINE SCIENCE + TECHNOLOGY DEVELOPMENT CO., LTD., TIANJIN |
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CP03 | Change of name, title or address |
Address after: 300192 No. 24, Nankai District, Tianjin, Yuquanlu Road Co-patentee after: Tianjin Taipu Pharmaceutical Science & Technology Development Co., Ltd. Patentee after: Tianjin Medicine Research Institute of Pharmaceutical Co., Ltd. Address before: 300193 Tianjin City, Nankai District Anshan West Road No. 308 Co-patentee before: Tianjin Medicine Research Institute of Pharmaceutical Co., Ltd. Patentee before: Tianjin Taipu Pharmaceutical Science & Technology Development Co., Ltd. |
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TR01 | Transfer of patent right |
Effective date of registration: 20200414 Address after: 300192 No. 24, Nankai District, Tianjin, Yuquanlu Road Co-patentee after: TIANJIN TAIPU PHARMACEUTICAL Co.,Ltd. Patentee after: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH PHARMACEUTICAL RESPONSIBLE Co.,Ltd. Address before: 300192 No. 24, Nankai District, Tianjin, Yuquanlu Road Co-patentee before: TIANJIN TAIPU PHARMACEUTICAL SCIENCE & TECHNOLOGY DEVELOPMENT Co.,Ltd. Patentee before: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH PHARMACEUTICAL RESPONSIBLE Co.,Ltd. |
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TR01 | Transfer of patent right |