CN101318395B - Method of manufacturing medicinal cold-forming composite aluminum foil - Google Patents
Method of manufacturing medicinal cold-forming composite aluminum foil Download PDFInfo
- Publication number
- CN101318395B CN101318395B CN 200710041644 CN200710041644A CN101318395B CN 101318395 B CN101318395 B CN 101318395B CN 200710041644 CN200710041644 CN 200710041644 CN 200710041644 A CN200710041644 A CN 200710041644A CN 101318395 B CN101318395 B CN 101318395B
- Authority
- CN
- China
- Prior art keywords
- aluminum foil
- composite
- preparation
- compound
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Laminated Bodies (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a preparation method for a medical cold-forming compound aluminum foil. The first compounding step of the method is adopting a bond to carry out compounding on a PA film and an aluminum foil one surface of which is coated with a bottom sizing agent to obtain a compound film I; the second compounding step of the method is using the bond to carry out compounding on the compound film I obtained in the first step and the PVC of an inner layer and obtain a compound film II; finally curing the compound film II is carried out to obtain the medical forming compound aluminum foil. The erichsen number of the medical cold-forming compound aluminum foil prepared by the invention is more than or equal to 10mm and the thickness is 0.1mm. Besides, the anti-chemical performance is excellent. The medical cold-forming compound aluminum foil prepared by the invention completely solves the defects similar to those of the prior medical compound aluminum foils and is prepared through a reasonable production technique by utilizing the environment-protective materials like nylon (PA), aluminum foil, PVC, bond, etc. High barrier materials are adopted by the invention; therefore, the transmittance of hydrosphere and oxygen is almost zero; the preparation method for a medical cold-forming compound aluminum foil has the largest characteristics of high barrier property, safety andinnocuity; the safety of the medicine is essentially ensured.
Description
Technical field
The present invention relates to a kind of preparation method of drug packing material, particularly the preparation method of non-toxic, environmental friendly medicinal cold-forming composite aluminum foil.
Background technology
Medical bubble-cap is packed same PVC (polyvinyl chloride) and has been existed for many years in China, and as the material of packaged pharmaceuticals, it has good processing characteristics and light and handy quality, but medicinal PVC exists the hidden danger on the safety.At first it is chloride, and what can be subject to the pollution of chlorine in long medicine of storage life, and this health to human body can be brought very large recessiveness infringement.Secondly, medicinal PVC be that the transit dose of aqueous vapor and oxygen is larger, be fatal on the impact of the stability of drug quality, it has shortened storage and the period of guarantee of medicine greatly, the security of medicine has also reduced.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of preparation method of five poisonous creatures: scorpion, viper, centipede, house lizard, toad environment-friendly type medicinal cold-forming composite aluminum foil, to solve the existing existing weak point of PVC medical bubble-cap.
Technical problem to be solved by this invention can be achieved through the following technical solutions:
A kind of preparation method of medicinal cold-forming composite aluminum foil comprises the steps:
1, the first composite steps, this step are to adopt adhesive to carry out the compound composite membrane I of getting on PA film and the aluminium foil that simultaneously scribbles silane coupling agent;
2, the second composite steps, this step are that composite membrane I and internal layer PVC that the first composite steps obtains are carried out the compound composite membrane II that obtains with adhesive;
3, the composite membrane II that second step is obtained carries out slaking and obtains medicinal moulding clad aluminum foil.
In preparation method of the present invention, the composite pressure that the first composite steps adopts is 4-5kg/cm
2, combined temp is 65-75 ℃, hauling speed is 60-100m/ minute.The glue-spread of the first composite steps is 5-6g/m
2
The composite pressure that the second composite steps adopts is 4-5kg/cm
2, combined temp is 65-75 ℃, hauling speed is 60-100m/ minute.The glue-spread of the second composite steps is 3-4g/m
2
In preparation method of the present invention, it is the urethane adhesives of 60-70% that binding agent adopts constant concentration, a kind of including but not limited in ethyl ester, the butanone of impregnation solvent.Gelatin viscosity is the 20-30S/4 cup.
In preparation method of the present invention, silane coupling agent is that constant concentration is 20% epobond epoxyn, a kind of including but not limited in ethyl ester, the butanone of impregnation solvent.Gelatin viscosity is the 20-30S/4 cup.
In preparation method of the present invention, the thickness of PA film is 25 μ m, the thickness 45-50 μ m of aluminium foil.
In preparation method of the present invention, curing temperature is 55-60 ℃, and the curing time is more than 8 days.
Adopt the medicinal cold-forming composite aluminum foil Erichsen number 〉=10mm of the present invention's preparation, thickness is 0.1mm.Anti-chemistry is good.The medicinal cold-forming composite aluminum foil of the present invention preparation has thoroughly solved shortcoming like the medicinal clad aluminum foil in the past, and it utilizes the environment-friendly materials such as nylon (PA), aluminium foil, PVC and adhesive to be prepared from through rational production technologies.It adopts high barrier material, so the transmitance of aqueous vapor and oxygen is almost nil, high barrier and the safe five poisonous creatures: scorpion, viper, centipede, house lizard, toad are characteristics of its maximum, and the security of medicine has been had basic assurance.Be mingled with without bubble, free from extraneous odour between compound medicinal cold-forming composite aluminum foil, come off without peeling off, solvent-free smell, excessive without compound adhesive, surface nondestructive is hindered.
Description of drawings
Fig. 1 is process chart of the present invention.
Fig. 2 is the medicinal cold-forming composite aluminum foil structural representation that the present invention prepares.
Among the figure: 1 is the PA layer, and 2 is polyurethane binder layer, and 3 is aluminium foil, and 4 is polyurethane binder layer, and 5 is the PVC layer.
The specific embodiment
For technological means, creation characteristic that the present invention is realized, reach purpose and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.
The medicinal cold-forming composite aluminum foil of the present invention's preparation for the packing of solid (tablet, capsule, granule, pulvis etc.), is a kind of packaging material of present a kind of higher gears, can make the medicine shelf life be increased to 3-5.Concrete structure is seen Fig. 2,
The thickness of nylon PA layer is 25 μ m, the thickness 45-50 μ m of aluminium foil.This medicinal cold-forming composite aluminum foil width also can be decided according to user's needs less than 1000mm, in 40mm, or decides according to user's needs under the volume external diameter.
The allowable error of this medicinal cold-forming composite aluminum foil is: width difference is between ± 1-1.5, and thickness error is controlled at ± 10%, and the volume outside diameter tolerance is ± 10%.
Referring to Fig. 1, the preparation method of this medicinal cold-forming composite aluminum foil comprises: the first composite steps, the second composite steps, unload the volume step, maturation stage, cut step, checking procedure, packaging step etc.Wherein most importantly the first composite steps, the second composite steps and maturation stage.Certainly can also be on medicinal cold-forming composite aluminum foil printing word.After the proportioning of specification requirement takes by weighing printing ink and solvent, pour in the mixer, stir and treat that printing ink dissolves fully, and reach technological requirement and viscosity and color, then allocate the complete printing machine of delivering to and carry out outer PA layer 1 and print.During printing, PA layer 1 film through being up to the standards delivered to by the printing machine, and be placed on the unwinding device, printing plate cylinder of all kinds is installed, and the deployed color ink that respectively overlaps is injected ink tank, put on printing element by required printing tricks, process hot blast drying tunnel is to wrap-up, adjust good hand, unwinding tension, machine, semi-finished product after quality inspection is qualified, deliver to carry out on the dry compound machine compound.Print speed printing speed＜120 rev/min.
The first composite steps adopts adhesive to carry out the compound composite membrane I of getting on the aluminium foil that PA film and one side scribble silane coupling agent; To be contained in through the PA film that is up to the standards on the dry compound machine gluing unwinding device, and pass through glue spreader, heated-air drying, compound thermal cylinder to Scroll, adjust the rolling unwinding tension, the heated-air drying temperature is to 70-80 ℃, the compound thermal bowl temperature is to 65-75 ℃, automatic deviation rectifying device is opened compounding machine.Be that the aluminium foil of 45-50 μ m is contained in and meets on the unwinding device simultaneously with the thickness that is up to the standards, scribble silane coupling agent at aluminium foil in advance, silane coupling agent is that constant concentration is 20% epobond epoxyn, and the viscosity that adopts the ethyl ester solvent to be diluted to silane coupling agent is the 20-30S/4 cup.Adhesive in the glue groove is transferred to the printing film surface, and process heated-air drying drying tunnel vapors away solvent and aluminium foil is compound on the compound thermal cylinder, and rolling obtains composite membrane I.Composite pressure is to 4-5kg/cm
2, the hauling speed of control compounding machine is 60-100m/ minute.
The glue-spread of the first composite steps is 5-6g/m
2
The second composite steps is that the composite membrane I that the first composite steps obtains is placed on the gluing unwinding device, and internal layer PVC is contained on the compound unwinding device, carries out the compound composite membrane II that obtains with adhesive according to the method for the first composite steps.The glue-spread of the second composite steps is 3-4g/m
2
It is the urethane adhesives of 60-70% that binding agent in the recombination process adopts constant concentration, and the impregnation solvent is ethyl ester.Gelatin viscosity is the 20-30S/4 cup.
Above-mentioned composite membrane II is delivered to curing chamber carry out celluloid ink curing, curing temperature is 55-60 ℃, and the curing time is more than 8 days.Composite membrane II should hang in the slaking baking oven (chamber) during slaking, horizontal departure＜0.5mm
The present invention also can adopt quick adhesive composite curing.
Said method uses material, needs the single face sided corona treatment such as the PA film, the printing surface gluing.PVC film double-sided sided corona treatment.The thin black width of the outer PA of compound tense should be less than aluminium foil width 10-20mm, and internal layer PVC thin-film width should be greater than aluminium foil width 10-20mm.
The blade interlock speed of cutting machine is 0.3-0.5mm/ second when cutting, and cuts speed 〉=80m/min, maximum speed 220m/min.Cut the flatness of card less than 1mm.
More than show and described basic principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that describes in above-described embodiment and the specification just illustrates principle of the present invention; the present invention also has various changes and modifications without departing from the spirit and scope of the present invention, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.
Claims (5)
1. the preparation method of a medicinal cold-forming composite aluminum foil is characterized in that, comprises the steps:
(1), the first composite steps, this step is to adopt adhesive to carry out compound composite membrane I on the aluminium foil that PA film and one side scribble silane coupling agent,
Wherein, the composite pressure that adopts is 4-5kg/cm
2, combined temp is 65-75 ℃, and hauling speed is 60-100m/ minute, and glue-spread is 5-6g/m
2,
It is 20% epobond epoxyn that described silane coupling agent adopts constant concentration, and the impregnation solvent comprises a kind of in ethyl ester, the butanone, and gelatin viscosity is the 20-30S/4 cup;
(2), the second composite steps, this step is that composite membrane I and internal layer PVC that the first composite steps obtains are carried out the compound composite membrane II that obtains with adhesive,
Wherein, the composite pressure that adopts is 4-5kg/cm
2, combined temp is 65-75 ℃, and hauling speed is 60-100m/ minute, and glue-spread is 3-4g/m
2
(3), the composite membrane II that second step is obtained carries out slaking and obtains medicinal moulding clad aluminum foil.
2. the preparation method of medicinal cold-forming composite aluminum foil according to claim 1, it is characterized in that, it is the urethane adhesives of 60-70% that described adhesive adopts constant concentration, and the impregnation solvent comprises a kind of in ethyl ester, the butanone, and gelatin viscosity is the 20-30S/4 cup.
3. the preparation method of medicinal cold-forming composite aluminum foil according to claim 1 is characterized in that, the thickness of described PA film is 25 μ m.
4. the preparation method of medicinal cold-forming composite aluminum foil according to claim 1 is characterized in that, the thickness of described aluminium foil is 45-50 μ m.
5. the preparation method of medicinal cold-forming composite aluminum foil according to claim 1 is characterized in that, described curing temperature is 55-60 ℃, and the curing time is more than 8 days.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710041644 CN101318395B (en) | 2007-06-05 | 2007-06-05 | Method of manufacturing medicinal cold-forming composite aluminum foil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710041644 CN101318395B (en) | 2007-06-05 | 2007-06-05 | Method of manufacturing medicinal cold-forming composite aluminum foil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101318395A CN101318395A (en) | 2008-12-10 |
| CN101318395B true CN101318395B (en) | 2013-03-13 |
Family
ID=40178771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200710041644 Active CN101318395B (en) | 2007-06-05 | 2007-06-05 | Method of manufacturing medicinal cold-forming composite aluminum foil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101318395B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102285198B (en) * | 2011-06-23 | 2014-05-07 | 广东东南薄膜科技股份有限公司 | Laminating method |
| CN102381004B (en) * | 2011-09-21 | 2014-09-10 | 扬州吉瑞尔包装材料有限公司 | Processing technology of cold-forming aluminium foil |
| CN102502054A (en) * | 2011-10-20 | 2012-06-20 | 利辛县宏达铝塑包装有限公司 | Aluminum-foil composite bag and preparation method thereof |
| CN102922856B (en) * | 2012-11-06 | 2015-05-27 | 江苏科技大学 | Method for preparing officinal cold forming composite aluminum foil |
| CN102909917A (en) * | 2012-11-16 | 2013-02-06 | 江苏科技大学 | Manufacture method for environment-friendly non-toxic cold forming composite aluminum foil for medicine |
| CN103538350B (en) * | 2013-10-16 | 2016-04-27 | 江苏真美包装科技有限公司 | A kind of solvent-free cold stamping shaped composite membrane production method |
| CN105129221B (en) * | 2015-07-30 | 2017-08-25 | 浙江金石包装有限公司 | The manufacture method of aluminum foil sealing film |
| CN109664573B (en) * | 2018-12-25 | 2020-07-17 | 常州市华健药用包装材料股份有限公司 | Printable high-strength solid medicinal cold stamping forming composite hard sheet |
| CN113954472A (en) * | 2021-09-28 | 2022-01-21 | 江苏真美包装科技有限公司 | High-strength wear-resistant composite packaging film and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1426933A (en) * | 2001-12-13 | 2003-07-02 | 刘继福 | High sealing cold pressing type packaging aluminium |
| CN2603026Y (en) * | 2003-01-27 | 2004-02-11 | 刘继福 | Cold stamping type plastics-aluminium combined diaphragm for high seal package |
| CN1597310A (en) * | 2004-08-11 | 2005-03-23 | 刘继福 | High sealing cold punching press shaped bubble cup plustic aluminium composite hard sheet and its production technology |
| CN2719566Y (en) * | 2004-07-23 | 2005-08-24 | 江阴宝柏包装有限公司 | High-barrier cold-forming aluminium die |
| CN1748995A (en) * | 2005-10-13 | 2006-03-22 | 牛科 | Film coated aluminum foil for medicine and its producing method |
-
2007
- 2007-06-05 CN CN 200710041644 patent/CN101318395B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1426933A (en) * | 2001-12-13 | 2003-07-02 | 刘继福 | High sealing cold pressing type packaging aluminium |
| CN2603026Y (en) * | 2003-01-27 | 2004-02-11 | 刘继福 | Cold stamping type plastics-aluminium combined diaphragm for high seal package |
| CN2719566Y (en) * | 2004-07-23 | 2005-08-24 | 江阴宝柏包装有限公司 | High-barrier cold-forming aluminium die |
| CN1597310A (en) * | 2004-08-11 | 2005-03-23 | 刘继福 | High sealing cold punching press shaped bubble cup plustic aluminium composite hard sheet and its production technology |
| CN1748995A (en) * | 2005-10-13 | 2006-03-22 | 牛科 | Film coated aluminum foil for medicine and its producing method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101318395A (en) | 2008-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101318395B (en) | Method of manufacturing medicinal cold-forming composite aluminum foil | |
| CN104136025A (en) | Adhesive skin patch | |
| CN103481626B (en) | A kind of production technology of PVC/PE/PVDC composite sheet | |
| CN102895926A (en) | Moistureproof treatment method for soft capsules | |
| CN207347470U (en) | A kind of coloured rupture pressure disc | |
| CN109849433A (en) | A kind of packaging bag production method | |
| CN106061722A (en) | Method for manufacturing corrugated cardboard with improved air permeability and breathability | |
| CN105073930B (en) | The method and corresponding adhesive tape of penetrant are removed from planar structure body | |
| CN201132408Y (en) | Medical cold forming composite aluminum foil | |
| FR2288514A1 (en) | Formed products film coating - using aqs solutions of water-soluble cellulose ethers | |
| CN111284049A (en) | Graphene antibacterial modified plastic film for medicine packaging and preparation method thereof | |
| AR084357A1 (en) | WATER SOLUBLE PACKING FILMS FOR AN ACID PRODUCT WITH HIGH WATER CONTENT AND METHOD TO PRODUCE THE SAME | |
| CN203567280U (en) | Suppository composite membrane | |
| CN116198187A (en) | Composite membrane for oral liquid medicine and preparation method thereof | |
| CN102807789A (en) | High-temperature-resistant ink for packaging of medical aluminum foil | |
| CN103157126B (en) | Woundplast glue and preparing method thereof | |
| JP5207473B2 (en) | Encapsulated oxygen detector | |
| CN201665649U (en) | Environmental-friendly pressure sensitive adhesive tape for light and biological degradation | |
| CN101361979B (en) | Solid preparation film coating agent and preparation method thereof | |
| CN204701230U (en) | Polyvinyl medicine composite packing film | |
| CN105172300A (en) | Multi-layer coextrusion cast film | |
| CN204701219U (en) | Polyvinyl chloride cold stamping solid medicinal composite hard sheet | |
| CN103568456A (en) | Compounding technology by taking polyacrylic acid as adhesive | |
| CN202399606U (en) | Composite film for packaging medicine | |
| CN204701216U (en) | Medical suppository composite membrane |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |