CN101318008A - Method for preparing capsule for expelling cold and relieving exterior syndrome - Google Patents

Method for preparing capsule for expelling cold and relieving exterior syndrome Download PDF

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Publication number
CN101318008A
CN101318008A CNA2008101406074A CN200810140607A CN101318008A CN 101318008 A CN101318008 A CN 101318008A CN A2008101406074 A CNA2008101406074 A CN A2008101406074A CN 200810140607 A CN200810140607 A CN 200810140607A CN 101318008 A CN101318008 A CN 101318008A
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CN
China
Prior art keywords
exterior syndrome
radix
relieving exterior
capsule
expelling cold
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Pending
Application number
CNA2008101406074A
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Chinese (zh)
Inventor
王忠东
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LUOYANG ZISHENG TECHNOLOGY DEVELOPMENT Co Ltd
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LUOYANG ZISHENG TECHNOLOGY DEVELOPMENT Co Ltd
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Application filed by LUOYANG ZISHENG TECHNOLOGY DEVELOPMENT Co Ltd filed Critical LUOYANG ZISHENG TECHNOLOGY DEVELOPMENT Co Ltd
Priority to CNA2008101406074A priority Critical patent/CN101318008A/en
Publication of CN101318008A publication Critical patent/CN101318008A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a manufacturing method of the capsules for dispelling cold and relieving exterior syndrome. In the invention, eight medicinal materials of angelica, processed radix aconiti, processed radix aconiti kusnezoffii, asarum, tuber of pinellia ternate, radix scutellariae, ginger and prepared licorice are carried out fine treatment to make into dry drug powder, the dry drug powder and magnesium stearate are mixed evenly according to proportion, and are made into wet grains by using ethanol as a wetting agent, dried, put into capsules, thus obtaining the product. The composition of the medicine of the invention is simple and specific, technics is advanced, quality is controlled easily, technical content is high, medicine taking is convenient, mouthfeel is good, moisture is not absorbed easily, and stability is good; the capsules are characterized in that the level of biology utilization is high, curative effect is the same as the other medicament forms, etc. The preparation is designed reasonably, medicine taking is convenient, carrying is convenient, and the preparation has special curative effect for dispelling cold and relieving exterior syndrome.

Description

A kind of manufacture method of capsule for expelling cold and relieving exterior syndrome
Technical field
The present invention relates to a kind of medicine of capsule for expelling cold and relieving exterior syndrome.Especially a kind of Rhizoma Et Radix Notopterygii, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata etc. eight flavor Chinese crude drugs are made into the manufacture method that capsule is used for the treatment of expelling cold and relieving exterior syndrome.
Background technology
Treating at present expelling cold and relieving exterior syndrome disease Chinese patent medicine commonly used clinically has a lot, and they differ from one another, and goodish effect is all arranged; But the medicine of controlling expelling cold and relieving exterior syndrome is still based on Western medicine, and the Western medicine effect is often too single again.Someone once designed Chinese crude drugs such as Radix Paeoniae Rubra, Rhizoma Smilacis Glabrae was made into tablet, and adjuvant is soluble starch, Pulvis Talci, magnesium stearate, but this product stability is poor, and the moisture absorption is rotten easily, and additive is many in the tablet, and active substance content is lower, and dose is big.
Summary of the invention
Be made into a kind of capsule after the objective of the invention is to Rhizoma Et Radix Notopterygii, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata etc. eight flavor Chinese crude drugs are extracted effective ingredient, this capsule can overcome the deficiency that existing product exists, and for expelling cold and relieving exterior syndrome unique curative effect is arranged.
The present invention is achieved in that
The selected herbal raw material of the present invention is eight flavors, and it is made up of the proportioning of following parts by weight: 0.3 part of Rhizoma Et Radix Notopterygii, 0.2 part of Radix Aconiti Preparata, 0.2 part of Radix Aconiti Kusnezoffii Preparata, 0.1 part of Herba Asari, 0.3 part of Rhizoma Pinelliae, 0.3 part of Radix Scutellariae, 0.3 part in Rhizoma Zingiberis Recens, 0.2 part of Radix Glycyrrhizae Preparata.
The manufacture method of capsule for expelling cold and relieving exterior syndrome: get Rhizoma Et Radix Notopterygii, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Herba Asari, Rhizoma Pinelliae, Radix Scutellariae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae Preparata pulverize separately and become fine powder, cross 100 mesh sieves; Decoct with water secondary, the decocting that adds for the first time 8 times boiled 1.5 hours, and the decocting that adds 8 times of amounts for the second time boiled merging filtrate 1.5 hours, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), and spray drying is made dried cream powder, with above-mentioned fine powder mixing, must do medicated powder, calculate: get dried medicated powder, magnesium stearate in 1: 0.05~0.1 ratio mixing, make wet granular as wetting agent with the ethanol of simmer down to 70%~90% with composition by weight.Drying is made dried granule, and is encapsulated, promptly.
Capsule for expelling cold and relieving exterior syndrome of the present invention is that it constitutes simple, clear and definite, quality and is easy to control with Rhizoma Et Radix Notopterygii, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata etc. the eight flavor Chinese crude drugs medicine that to be raw material make by advanced person's preparation method, the capsule of making is the Sugarless type preparation, can increase the crowd of being suitable for, capsule is Chinese medicine advanced person's a dosage form, with high content of technology, patient's taking convenience, mouthfeel is good, be difficult for the moisture absorption, good stability; It is few that this product and tablet have been compared dose, and curative effect has the characteristics of equivalence with it.This capsule has definite curative effect to expelling cold and relieving exterior syndrome, especially expelling cold and relieving exterior syndrome is had unique curative effect.Its volume is little, and is easy to carry, the standing medication that is fit to family and travels away from home.
Embodiment 1:
Calculate with composition by weight: get dried medicated powder 500g, magnesium stearate 50g mixing in 1: 0.1 ratio, make wet granular as wetting agent with the edible ethanol 6ml of simmer down to 90%, dry about 70 ℃, make capsule, be up to the standards, powdery promptly gets the capsule for expelling cold and relieving exterior syndrome finished product.
The specific embodiment:
Rhizoma Et Radix Notopterygii 0.3g, Radix Aconiti Preparata 0.23g, Radix Aconiti Kusnezoffii Preparata 0.2g, Herba Asari 0.1g, Rhizoma Pinelliae 0.3g Radix Scutellariae 0.3g, Rhizoma Zingiberis Recens 0.3g, Radix Glycyrrhizae Preparata 0.2g.Be ground into fine powder, cross 100 mesh sieves.Amount to the 1720g medical material, decoct with water secondary, the decocting that adds 13.76kg for the first time boiled 1.5 hours, and the decocting that adds 13.76kg for the second time boiled 1.5 hours, merging filtrate, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), spray drying, baking temperature is about 120 ℃, make dried cream powder,, must do medicated powder with above-mentioned fine powder mixing.Two components calculate in one: take by weighing dried medicated powder 500g, magnesium stearate 25g mixing in 1: 0.05 ratio, make wet granular as wetting agent, drying about 50 ℃ with the edible ethanol 4ml of simmer down to 70%, make capsule, be up to the standards, powdery promptly gets the capsule for expelling cold and relieving exterior syndrome finished product.
The function of this product cures mainly: expelling cold and relieving exterior syndrome, numbness relieving and pain relieving.

Claims (4)

1, a kind of manufacture method of capsule for expelling cold and relieving exterior syndrome is characterized in that it is to have the raw material of following parts by weight to make; 0.3 part of Rhizoma Et Radix Notopterygii, 0.2 part of Radix Aconiti Preparata, 0.2 part of Radix Aconiti Kusnezoffii Preparata, 0.1 part of Herba Asari, 0.3 part of Rhizoma Pinelliae, 0.3 part of Radix Scutellariae, 0.3 part in Rhizoma Zingiberis Recens, 0.2 part of Radix Glycyrrhizae Preparata.
2, a kind of manufacture method of capsule for expelling cold and relieving exterior syndrome.It is characterized in that; Get Rhizoma Et Radix Notopterygii, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Herba Asari, Rhizoma Pinelliae, Radix Scutellariae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae Preparata, pulverize separately becomes fine powder, crosses 100 mesh sieves; Decoct with water the secondary merging filtrate, filter, filtrate is concentrated into the clear paste that relative density is 1.10 (70 ℃), and spray drying is made dried cream powder, with above-mentioned fine powder mixing, must do medicated powder; Calculate with composition by weight: get dried medicated powder, make wet granular with the ethanol of simmer down to 70%~90% as wetting agent, drying is made dried granule, and is encapsulated, promptly.
3, the manufacture method of a kind of capsule for expelling cold and relieving exterior syndrome according to claim 2 is characterized in that: the temperature of spray drying chamber is 100 ℃~120 ℃.
4, the manufacture method of a kind of capsule for expelling cold and relieving exterior syndrome according to claim 2 is characterized in that; The baking temperature temperature is 50 ℃~70 ℃.
CNA2008101406074A 2008-07-15 2008-07-15 Method for preparing capsule for expelling cold and relieving exterior syndrome Pending CN101318008A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2008101406074A CN101318008A (en) 2008-07-15 2008-07-15 Method for preparing capsule for expelling cold and relieving exterior syndrome

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2008101406074A CN101318008A (en) 2008-07-15 2008-07-15 Method for preparing capsule for expelling cold and relieving exterior syndrome

Publications (1)

Publication Number Publication Date
CN101318008A true CN101318008A (en) 2008-12-10

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Application Number Title Priority Date Filing Date
CNA2008101406074A Pending CN101318008A (en) 2008-07-15 2008-07-15 Method for preparing capsule for expelling cold and relieving exterior syndrome

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CN (1) CN101318008A (en)

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Open date: 20081210