CN101310753A - Analgesic and anticancer plaster and preparation method thereof - Google Patents
Analgesic and anticancer plaster and preparation method thereof Download PDFInfo
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- CN101310753A CN101310753A CNA2007100491446A CN200710049144A CN101310753A CN 101310753 A CN101310753 A CN 101310753A CN A2007100491446 A CNA2007100491446 A CN A2007100491446A CN 200710049144 A CN200710049144 A CN 200710049144A CN 101310753 A CN101310753 A CN 101310753A
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Abstract
The invention discloses an analgesic and anti-cancer plaster, which is prepared by raw materials such as pedate pinallia jackinthepulpit rhizome, common monkshood mother root, giant typhonium rhizome, frankincense, myrrh, long pepper, manchurian wildginger, dahurian angelica root, yanhusuo, pricklyash peel, pepper, aconitum brachypodum diels, edible tulip, toad venom, resina draconis, borneol, castor oil and litharge, etc. The analgesic and anti-cancer plaster has low cost, significant analgesic effect, exact efficacy, safety, no toxicity or side effects and very convenient usage. The invention further discloses a preparation method of the analgesic and anti-cancer plaster.
Description
Technical field
The invention belongs to medical technical field, particularly a kind of anticancer plaster and preparation method thereof that eases pain.
Background technology
Cancer is one of disease of current serious threat human health.China has the cancer patient about 2,600,000 at present, annual new cancer diagnosis patient about 1,800,000.Pain is one of common sympton of cancer patient experience, and according to The World Health Organization's statistics, nearly half the cancer patient in the whole world is with in various degree pain, and about have serious, insufferable pain more than 30%.Pain causes great influence to patient's body, spirit, psychology, social inter personal contact.Therefore pain management effectively make the cancer pain patient equally with the normal person dignity is arranged spend the remaining years in comfort in the face of life and society, thereby the life quality of raising patients with advanced cancer is worldwide major issue, also is the important topic in the clinical position.WHO released " three ladders " analgesic treatments in 1986, in year surplus China's implementation " three ladders " analgesic treatments has ten, Cancer pain Therapy work is had large improvement.Yet, basic hospital owing to people to reasons such as the scruple of opioid addiction and fears, in the treatment work of cancer pain, still exist many problems.There are many cancer pain patients to fail to obtain pain therapy timely and effectively.
Plaster therapy is a kind of methods for the treatment of diseases of inner disease outer treat, and it borrows the path of meridians to bring into play its network that stimulates the menstrual flow away, row stagnate blood stasis dispelling, the function deep, the wind dispelling cold expelling of having one's ideas straightened out, in clinical practice, have letter, just, honest and clean, the characteristics tested.
Summary of the invention
The purpose of this invention is to provide a kind of easy to use, safe having no side effect and economic plaster with analgesia antitumaous effect.
Another object of the present invention provides the preparation method of the anticancer plaster of a kind of above-mentioned analgesia.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of anticancer plaster that eases pain, it is made by the following weight parts proportion raw material:
Rhizoma Arisaematis 10-50 part, Radix Aconiti 10-40 part, Rhizoma Typhonii 10-40 part, Olibanum 5-30 part,
Myrrha 5-30 part, BIBO 5-30 part, Herba Asari 5-30 part, Radix Angelicae Dahuricae 5-30 part,
Corydalis tuber 5-30 part, Pericarpium Zanthoxyli 5-30 part, Fructus Piperis 1-15 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 10-40 part,
Pseudobulbus Cremastrae Seu Pleiones 10-40 part, Venenum Bufonis 1-15 part, Sanguis Draxonis 1-20 part, Borneolum Syntheticum 1-20 part,
Oleum Sesami 1000-2000 part, Plumbum preparatium 350-550 part.
The weight portion proportion optimization of above-mentioned each raw material is:
Rhizoma Arisaematis 20-30 part, Radix Aconiti 20-30 part, Rhizoma Typhonii 20-30 part, Olibanum 10-20 part,
Myrrha 10-20 part, BIBO 10-20 part, Herba Asari 10-20 part, Radix Angelicae Dahuricae 10-20 part,
Corydalis tuber 10-20 part, Pericarpium Zanthoxyli 10-20 part, Fructus Piperis 1-10 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 20-30 part,
Pseudobulbus Cremastrae Seu Pleiones 20-30 part, Venenum Bufonis 1-10 part, Sanguis Draxonis 5-15 part, Borneolum Syntheticum 1-10 part,
Oleum Sesami 1200-1800 part, Plumbum preparatium 400-500 part.
The weight portion proportioning of above-mentioned each raw material is more preferably:
25 parts of Rhizoma Arisaematiss, 25 parts of Radix Aconitis, 25 parts of Rhizoma Typhoniis, 15 parts of Olibanums,
15 parts of Myrrhas, 15 parts of BIBO, 15 parts of Herba Asaris, 15 parts of the Radixs Angelicae Dahuricae,
15 parts of corydalis tubers, 15 parts in Pericarpium Zanthoxyli, 5 parts in Fructus Piperis, 25 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s,
25 parts of Pseudobulbus Cremastrae Seu Pleioness, 5 parts of Venenum Bufoniss, 10 parts of Sanguis Draxonis, 5 parts of Borneolum Syntheticums,
1500 parts in Oleum Sesami, 450 parts in Plumbum preparatium.
Plumbum preparatium in the above-mentioned raw materials is the Plumbum preparatium, and its preparation method is: pure lead is placed in the iron pan heats, fry and move, utilize air to make it oxidation, be placed on pulverize in the stone mortar then; Use water rinse, the fine powder that drifts out through oxidation 24 hours, is ground into fine powder and sieves promptly again.
The plaster that the above-mentioned analgesia of the present invention is anticancer can prepare by the method that mainly comprises the steps:
(1), get the preceding 13 flavor raw medicinal materials (Rhizoma Arisaematis, Radix Aconiti, Rhizoma Typhonii, Olibanum, Myrrha, BIBO, Herba Asari, the Radix Angelicae Dahuricae, corydalis tuber, Pericarpium Zanthoxyli, Fructus Piperis, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Pseudobulbus Cremastrae Seu Pleiones) of described proportioning, put into Oleum Sesami and soaked 1-5 days;
(2), there is the Oleum Sesami of 13 flavor raw medicinal materials to boil (1) described immersion of step, endure withered removing slag (all become coke black to the crude drug surface then pull medicinal residues out) with slow fire then, add the Plumbum preparatium of described proportioning slowly, be stirred to and drip into pearl, receive cream, in the impouring cold water releasing fire-toxin 1-5 days again;
(3), the ointment of (2) step behind the releasing fire-toxin put into pot, heat to 60-80 ℃ and make it fusing, add Venenum Bufonis, Sanguis Draxonis and the Borneolum Syntheticum of described proportioning again, stir, make into cream drug and get final product.
In the above-mentioned preparation method, the whipping process in (2) step and (3) step uses non-ironworks such as waddy or bamboo pole to carry out.
Through the cream drug that above-mentioned (3) step makes, also can share and mount on the backing material in kraft paper, non-woven fabrics etc., use with convenient.
The plaster using method that the present invention is eased pain anticancer is: earlier affected part or sore spot are disinfected in alcohol (the sterilization area is greater than the plaster surface covered), plaster is spread on the surface get final product; Mount plaster on the backing material if adopt medicine have been shared in kraft paper, non-woven fabrics etc., burning things which may cause a fire disaster such as available lighter or wax candle toast its back side, and its Wen Huahou is applied ointment or plaster again; Change dressings about 48 hours.To the cancer pain patient, plaster of the present invention can be spread on the disease corresponding acupoints.
Compared with prior art, the invention has the beneficial effects as follows: the present invention ease pain anticancer plaster meticulously surplus the screening ten kind of a Chinese medicine make, very cheap with respect to its cost of analgesics such as morphine, dolantin, and its analgesic activity is obvious, determined curative effect, safe without toxic side effect is used also very convenient.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
But this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following embodiment.
Embodiment 1
The analgesia anticancer plaster of present embodiment for making by the following weight parts proportion raw material:
25 parts of Rhizoma Arisaematiss, 25 parts of Radix Aconitis, 25 parts of Rhizoma Typhoniis, 15 parts of Olibanums,
15 parts of Myrrhas, 15 parts of BIBO, 15 parts of Herba Asaris, 15 parts of the Radixs Angelicae Dahuricae,
15 parts of corydalis tubers, 15 parts in Pericarpium Zanthoxyli, 5 parts in Fructus Piperis, 25 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s,
25 parts of Pseudobulbus Cremastrae Seu Pleioness, 5 parts of Venenum Bufoniss, 10 parts of Sanguis Draxonis, 5 parts of Borneolum Syntheticums,
1500 parts in Oleum Sesami, 450 parts in Plumbum preparatium.
The method preparation of plaster that the present embodiment analgesia is anticancer by comprising the steps:
(1), get the preceding 13 flavor raw medicinal materials of described proportioning, put into Oleum Sesami and soaked 3 days;
(2), have the Oleum Sesami of 13 flavor raw medicinal materials to boil (1) described immersion of step, endure withered removing slag with slow fire then, add the Plumbum preparatium of described proportioning slowly, be stirred to Ramulus Salicis Babylonicae and drip into pearl, receive cream, again releasing fire-toxin 3 days in the impouring cold water;
(3), the ointment of (2) step behind the releasing fire-toxin put into pot, heat to 60-70 ℃ and make it fusing, add Venenum Bufonis, Sanguis Draxonis and the Borneolum Syntheticum of described proportioning again, stir, share again in mounting on the backing material non-woven fabrics, promptly with Ramulus Salicis Babylonicae.
Embodiment 2
The analgesia anticancer plaster of present embodiment for making by the following weight parts proportion raw material:
20 parts of Rhizoma Arisaematiss, 30 parts of Radix Aconitis, 10 parts of Rhizoma Typhoniis, 30 parts of Olibanums,
20 parts of Myrrhas, 10 parts of BIBO, 5 parts of Herba Asaris, 20 parts of the Radixs Angelicae Dahuricae,
30 parts of corydalis tubers, 20 parts in Pericarpium Zanthoxyli, 1 part in Fructus Piperis, 10 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s,
40 parts of Pseudobulbus Cremastrae Seu Pleioness, 15 parts of Venenum Bufoniss, 15 parts of Sanguis Draxonis, 20 parts of Borneolum Syntheticums,
1800 parts in Oleum Sesami, 400 parts in Plumbum preparatium.
The method preparation of plaster that the present embodiment analgesia is anticancer by comprising the steps:
(1), get the preceding 13 flavor raw medicinal materials of described proportioning, put into Oleum Sesami and soaked 1 day;
(2), have the Oleum Sesami of 13 flavor raw medicinal materials to boil (1) described immersion of step, endure withered removing slag with slow fire then, add the Plumbum preparatium of described proportioning slowly, be stirred to Ramulus Salicis Babylonicae and drip into pearl, receive cream, again releasing fire-toxin 5 days in the impouring cold water;
(3), the ointment of (2) step behind the releasing fire-toxin put into pot, heat to 70-80 ℃ and make it fusing, add Venenum Bufonis, Sanguis Draxonis and the Borneolum Syntheticum of described proportioning again, stir, share again in mounting on the backing material kraft paper, promptly with Ramulus Salicis Babylonicae.
Embodiment 3
The analgesia anticancer plaster of present embodiment for making by the following weight parts proportion raw material:
10 parts of Rhizoma Arisaematiss, 20 parts of Radix Aconitis, 30 parts of Rhizoma Typhoniis, 20 parts of Olibanums,
5 parts of Myrrhas, 20 parts of BIBO, 30 parts of Herba Asaris, 5 parts of the Radixs Angelicae Dahuricae,
10 parts of corydalis tubers, 30 parts in Pericarpium Zanthoxyli, 15 parts in Fructus Piperis, 20 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s,
30 parts of Pseudobulbus Cremastrae Seu Pleioness, 10 parts of Venenum Bufoniss, 5 parts of Sanguis Draxonis, 1 part of Borneolum Syntheticum,
1000 parts in Oleum Sesami, 500 parts in Plumbum preparatium.
The method preparation of plaster that the present embodiment analgesia is anticancer by comprising the steps:
(1), get the preceding 13 flavor raw medicinal materials of described proportioning, put into Oleum Sesami and soaked 5 days;
(2), have the Oleum Sesami of 13 flavor raw medicinal materials to boil (1) described immersion of step, endure withered removing slag with slow fire then, add the Plumbum preparatium of described proportioning slowly, be stirred to bamboo pole and drip into pearl, receive cream, again releasing fire-toxin 3 days in the impouring cold water;
(3), the ointment of (2) step behind the releasing fire-toxin put into pot, heat to 65-75 ℃ and make it fusing, add Venenum Bufonis, Sanguis Draxonis and the Borneolum Syntheticum of described proportioning again, stir, share again in mounting on the backing material non-woven fabrics, promptly with bamboo pole.
Embodiment 4
The analgesia anticancer plaster of present embodiment for making by the following weight parts proportion raw material:
50 parts of Rhizoma Arisaematiss, 10 parts of Radix Aconitis, 40 parts of Rhizoma Typhoniis, 10 parts of Olibanums,
30 parts of Myrrhas, 5 parts of BIBO, 10 parts of Herba Asaris, 10 parts of the Radixs Angelicae Dahuricae,
20 parts of corydalis tubers, 5 parts in Pericarpium Zanthoxyli, 10 parts in Fructus Piperis, 40 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s,
10 parts of Pseudobulbus Cremastrae Seu Pleioness, 1 part of Venenum Bufonis, 20 parts of Sanguis Draxonis, 10 parts of Borneolum Syntheticums,
1200 parts in Oleum Sesami, 550 parts in Plumbum preparatium.
The method preparation of plaster that the present embodiment analgesia is anticancer by comprising the steps:
(1), get the preceding 13 flavor raw medicinal materials of described proportioning, put into Oleum Sesami and soaked 2 days;
(2), have the Oleum Sesami of 13 flavor raw medicinal materials to boil (1) described immersion of step, endure withered removing slag with slow fire then, add the Plumbum preparatium of described proportioning slowly, be stirred to waddy and drip into pearl, receive cream, again releasing fire-toxin 3 days in the impouring cold water;
(3), the ointment of (2) step behind the releasing fire-toxin put into pot, heat to 60-70 ℃ and make it fusing, add Venenum Bufonis, Sanguis Draxonis and the Borneolum Syntheticum of described proportioning again, stir, share again in mounting on the backing material kraft paper, promptly with waddy.
Embodiment 5
The analgesia anticancer plaster of present embodiment for making by the following weight parts proportion raw material:
30 parts of Rhizoma Arisaematiss, 40 parts of Radix Aconitis, 20 parts of Rhizoma Typhoniis, 5 parts of Olibanums,
10 parts of Myrrhas, 30 parts of BIBO, 20 parts of Herba Asaris, 30 parts of the Radixs Angelicae Dahuricae,
5 parts of corydalis tubers, 10 parts in Pericarpium Zanthoxyli, 8 parts in Fructus Piperis, 30 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s,
20 parts of Pseudobulbus Cremastrae Seu Pleioness, 2 parts of Venenum Bufoniss, 1 part of Sanguis Draxonis, 15 parts of Borneolum Syntheticums,
2000 parts in Oleum Sesami, 350 parts in Plumbum preparatium.
The method preparation of plaster that the present embodiment analgesia is anticancer by comprising the steps:
(1), get the preceding 13 flavor raw medicinal materials of described proportioning, put into Oleum Sesami and soaked 4 days;
(2), have the Oleum Sesami of 13 flavor raw medicinal materials to boil (1) described immersion of step, endure withered removing slag with slow fire then, add the Plumbum preparatium of described proportioning slowly, be stirred to Ramulus Salicis Babylonicae and drip into pearl, receive cream, again releasing fire-toxin 2 days in the impouring cold water;
(3), the ointment of (2) step behind the releasing fire-toxin put into pot, heat to 60-70 ℃ and make it fusing, add Venenum Bufonis, Sanguis Draxonis and the Borneolum Syntheticum of described proportioning again, stir, make into cream drug, promptly.
Adopt the method for preparing plaster with the various embodiments described above similar methods or other, also can make the anticancer plaster of analgesia in parameter area of the present invention, that have different material medicine proportioning.
Claims (6)
1. anticancer plaster of analgesia, it is made by the following weight parts proportion raw material:
Rhizoma Arisaematis 10-50 part, Radix Aconiti 10-40 part, Rhizoma Typhonii 10-40 part, Olibanum 5-30 part,
Myrrha 5-30 part, BIBO 5-30 part, Herba Asari 5-30 part, Radix Angelicae Dahuricae 5-30 part,
Corydalis tuber 5-30 part, Pericarpium Zanthoxyli 5-30 part, Fructus Piperis 1-15 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 10-40 part,
Pseudobulbus Cremastrae Seu Pleiones 10-40 part, Venenum Bufonis 1-15 part, Sanguis Draxonis 1-20 part, Borneolum Syntheticum 1-20 part,
Oleum Sesami 1000-2000 part, Plumbum preparatium 350-550 part.
2. the anticancer plaster of analgesia according to claim 1 is characterized in that: the weight portion proportioning of described each raw material is:
Rhizoma Arisaematis 20-30 part, Radix Aconiti 20-30 part, Rhizoma Typhonii 20-30 part, Olibanum 10-20 part,
Myrrha 10-20 part, BIBO 10-20 part, Herba Asari 10-20 part, Radix Angelicae Dahuricae 10-20 part,
Corydalis tuber 10-20 part, Pericarpium Zanthoxyli 10-20 part, Fructus Piperis 1-10 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 20-30 part,
Pseudobulbus Cremastrae Seu Pleiones 20-30 part, Venenum Bufonis 1-10 part, Sanguis Draxonis 5-15 part, Borneolum Syntheticum 1-10 part,
Oleum Sesami 1200-1800 part, Plumbum preparatium 400-500 part.
3. the anticancer plaster of analgesia according to claim 1 is characterized in that: the weight portion proportioning of described each raw material is:
25 parts of Rhizoma Arisaematiss, 25 parts of Radix Aconitis, 25 parts of Rhizoma Typhoniis, 15 parts of Olibanums,
15 parts of Myrrhas, 15 parts of BIBO, 15 parts of Herba Asaris, 15 parts of the Radixs Angelicae Dahuricae,
15 parts of corydalis tubers, 15 parts in Pericarpium Zanthoxyli, 5 parts in Fructus Piperis, 25 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s,
25 parts of Pseudobulbus Cremastrae Seu Pleioness, 5 parts of Venenum Bufoniss, 10 parts of Sanguis Draxonis, 5 parts of Borneolum Syntheticums,
1500 parts in Oleum Sesami, 450 parts in Plumbum preparatium.
4. the preparation method of the anticancer plaster of the described analgesia of claim 1 mainly comprises the steps:
(1), get the preceding 13 flavor raw medicinal materials of described proportioning, put into Oleum Sesami and soaked 1-5 days;
(2), have the Oleum Sesami of 13 flavor raw medicinal materials to boil (1) described immersion of step, endure withered removing slag with slow fire then, add the Plumbum preparatium of described proportioning slowly, be stirred to and drip into pearl, receive cream, in the impouring cold water releasing fire-toxin 1-5 days again;
(3), the ointment of (2) step behind the releasing fire-toxin put into pot, heat to 60-80 ℃ and make it fusing, add Venenum Bufonis, Sanguis Draxonis and the Borneolum Syntheticum of described proportioning again, stir, make into cream drug and get final product.
5. the preparation method of the plaster that analgesia according to claim 4 is anticancer is characterized in that: the whipping process in described (2) step and (3) step uses non-ironwork to carry out.
6. the preparation method of the plaster that analgesia according to claim 4 is anticancer is characterized in that: the cream drug that will make through described (3) step, and share in kraft paper, non-woven fabrics etc. and mount on the backing material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100491446A CN101310753A (en) | 2007-05-22 | 2007-05-22 | Analgesic and anticancer plaster and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100491446A CN101310753A (en) | 2007-05-22 | 2007-05-22 | Analgesic and anticancer plaster and preparation method thereof |
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| CN101310753A true CN101310753A (en) | 2008-11-26 |
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| CNA2007100491446A Pending CN101310753A (en) | 2007-05-22 | 2007-05-22 | Analgesic and anticancer plaster and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103120700A (en) * | 2012-12-22 | 2013-05-29 | 北华大学 | Method for preparing arisaema heterophyllum polysaccharide with anti-tumor activity |
| CN104435573A (en) * | 2014-11-18 | 2015-03-25 | 毛毛 | External traditional Chinese medicine preparation for relieving cancer pain and preparation method thereof |
| CN108553633A (en) * | 2018-07-04 | 2018-09-21 | 宋广峰 | A kind of Dressed plaster and preparation method thereof for treating rheumatism and neck-shoulder pain, lumbago and leg pain |
| CN108671110A (en) * | 2018-08-21 | 2018-10-19 | 甘勇 | A kind of anticancer ointment |
-
2007
- 2007-05-22 CN CNA2007100491446A patent/CN101310753A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103120700A (en) * | 2012-12-22 | 2013-05-29 | 北华大学 | Method for preparing arisaema heterophyllum polysaccharide with anti-tumor activity |
| CN104435573A (en) * | 2014-11-18 | 2015-03-25 | 毛毛 | External traditional Chinese medicine preparation for relieving cancer pain and preparation method thereof |
| CN108553633A (en) * | 2018-07-04 | 2018-09-21 | 宋广峰 | A kind of Dressed plaster and preparation method thereof for treating rheumatism and neck-shoulder pain, lumbago and leg pain |
| CN108671110A (en) * | 2018-08-21 | 2018-10-19 | 甘勇 | A kind of anticancer ointment |
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Open date: 20081126 |