CN101310703A - Foamable alcoholic composition - Google Patents
Foamable alcoholic composition Download PDFInfo
- Publication number
- CN101310703A CN101310703A CNA2008101277355A CN200810127735A CN101310703A CN 101310703 A CN101310703 A CN 101310703A CN A2008101277355 A CNA2008101277355 A CN A2008101277355A CN 200810127735 A CN200810127735 A CN 200810127735A CN 101310703 A CN101310703 A CN 101310703A
- Authority
- CN
- China
- Prior art keywords
- alcohol
- weight
- compositions
- lactic acid
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
A foamable composition includes greater than about 40 weight percent of an alcohol, based upon the total weight of the alcoholic composition, and a foaming surfactant selected from gemini surfactants, sulfuric acid esters, di-esters, C10-34 fatty alcohols, polyquaternium polymers, and combinations thereof.
Description
Technical field
The present invention relates to foamable alcoholic composition, especially contain and be selected from Gemini surfactant (geminisurfactant), sulfuric ester, diester, C
10-34The foaming surfactant of aliphatic alcohol, polyquaternary ammonium salt polymer and combination thereof.
Background technology
The foamed cleaning product is very common, partly because they are easy to expand from the teeth outwards.As if consumer like enjoying the foam soap product.Produce identical cleaning power, liquid or colloid need less foam, at least partially because the bigger surface area of this foam.The froth pulp of appropriate preparation can not produce traditional colloid or water clock that fluid product stood and splash, because this prescription can not disperse in liquid condition.This prevents from the base plate of the equipment that has used dispenser and wall are damaged.The production of froth pulp is easy to the colloid product, wherein usually contains the Powdered thickening agent that is difficult to handle.
For example the resistance aqueous foam cleaning product is described to contain surfactant, foaming and promotes for example foamed cleaning composition of the water of dihydroxylic alcohols and at least 80 weight % of solvent.
Alcohol formula (alcoholic) product is usually used in the disinfectant as skin.But, based on the froth pulp ambigendi locus of alcoholic composition, because known alcohol has stronger antifoam performance.Although there is aerosol base alcohol formula foam, these aerosol products involve great expense than non-aerosol foam usually.
The skin degerming prescription is described to contain: the alcohol that (a) accounts for the about 50-80 weight of whole compositionss %; (b) about 0.02 weight %-5 weight % block copolymer; (c) foaming surfactant of the about 25 weight % of about 5 weight %-; (d) emulsifying agent of the about 3 weight % of about 0 weight %-; (e) emulsifying agent of the about 5 weight % of about 1 weight %-; (f) antiseptic of the about 5 weight % of about 0 weight %-; (g) abluent of the about 10 weight % of about 1 weight %-; (h) polyalkylene glycol of the about 5 weight % of about 0.5 weight %-; (i) humidizer and/or the emollient of the about 5 weight % of about 0.05 weight %-; (j) water of the about 30 weight % of about 6 weight %-.Described foaming surfactant is for example cocos nucifera oil diglycollic amide, amine oxide for example N-isostearoyl amido ethyl-N hydroxyethyl alanine sodium and a lauroyl amido CAB surfactant of hexadecane dimethyl oxidation amine and amphoteric surfactant for example of fatty 2-Sulfosuccinic acid ammonium, cocoyl diethanolamine, alkanolamide.
Commercially available non-aerosol alcohol formula foam disperses with specific perfluoroalkyl phosphate surfactant preparation and from the foaming pump device.But the foam of Chan Shenging is of short duration like this, can get started to dwindle or liquefy to be few water liquid.Used organic silicon surfactant preparation foam, but this prescription is not suitable for all applications.Siliceous prescription is independent of the surface, can hinder surface treatment afterwards.Therefore, need can extensive use foamable alcoholic composition.
Summary of the invention
One or more embodiment of the present invention provides foamable composite, and it contains the alcohol of about at least 40 weight %, presses the total weight of the compositions of this alcohol formula; Be selected from Gemini surfactant, sulfuric ester, diester, C
10-34The foaming surfactant of aliphatic alcohol, polyquaternary ammonium salt polymer and combination thereof, prerequisite are that foaming surfactant contains the anion diester, and this foamable composite also contains aliphatic alcohol or foamed promoter.
One or more embodiment of the present invention also provides bactericidal composition, and it contains the alcohol of about at least 50 weight %, presses the total weight of the compositions of this alcohol formula; With the about 4 weight % of about 0.05-be selected from Gemini surfactant, sulfuric ester, diester, C
10-34The foaming surfactant of aliphatic alcohol, polyquaternary ammonium salt polymer and combination thereof; The foamed promoter that is selected from PVP/VA copolymer, P/VA copolymer, collagen amino acid, solubility elastin laminin and cocoyl hydrolysis amaranth albumen sodium salt (sodium cocoylhydrolyzed amaranth protein) with the about 4 weight % of about 0.005-.
One or more embodiment of the present invention also provides the foamy method of pure formula that is used to form, and this method comprises combination alcohol, is selected from Gemini surfactant, sulfuric ester, diester, C
10-34The foaming surfactant of aliphatic alcohol, polyquaternary ammonium salt polymer and combination thereof forms foamable alcoholic composition, and prerequisite is that foaming surfactant contains the anion diester, and this foamable composite also contains aliphatic alcohol or foamed promoter; Described alcoholic composition and air or noble gas mixed in mixing chamber form mixture; Described mixture is formed foam by mesh screen, press the total weight of the compositions of this alcohol formula, foamable alcoholic composition described here contains the alcohol of about at least 40 weight %.
Detailed Description Of The Invention
Comprise pure and mild at least foaming surfactant at least according to foamable alcoholic composition of the present invention.In one embodiment, this alcohol is low-grade alkane alcohol, for example contains the alcohol of 1-4 carbon atom.Typically, these alcohol have antimicrobial character.The example of low-grade alkane alcohol includes, but not limited to methanol, ethanol, propanol, isopropyl alcohol, butanols, isobutanol, tert-butyl alcohol and composition thereof.In one embodiment, this alcohol contains ethanol.
Generally speaking, press the total weight of alcoholic composition, alcoholic composition contains the alcohol of about at least 40 weight %.Press the total weight of alcoholic composition, in one embodiment, this alcoholic composition contains the alcohol of about at least 45 weight %, in another embodiment, this alcoholic composition contains the alcohol of at least 50 weight %, and in another embodiment, this alcoholic composition contains the alcohol of about at least 60 weight %.Under specific situation, need more or less alcohol, depend on other composition and/or its consumption that use in the said composition to a great extent.Press the total weight of alcoholic composition, in specific embodiment, this alcoholic composition contains the alcohol of the about 98 weight % of about 40 weight %-, in other embodiments, this alcoholic composition contains the alcohol of the about 95 weight % of about 45 weight %-, and in another embodiment again, this alcoholic composition contains the alcohol of the about 90 weight % of about 50 weight %-, and in another embodiment, this alcoholic composition contains the alcohol of the about 80 weight % of about 60 weight %-.
This foamable composite can contain C
1-9The mixture of alkanol.In one or more embodiments, foamable composite contains one or more C
1-4Alkanol and C
5-9The mixture of alkanol.This mixture can comprise primary, the second month in a season or the tertiary alcohol.
Foaming surfactant is given this alcoholic composition foam characteristics, can comprise Gemini surfactant (being also referred to as the dimeric surfactant), sulfuric ester, diester, aliphatic alcohol, polyquaternary ammonium salt polymer or its combination.
In one or more embodiments, this foaming surfactant comprises the Gemini surfactant.Opposite with the simple surfactant that is made of single hydrophilic head end and one or two hydrophobic tail end usually, the Gemini surfactant has two or more head ends and two or more tail end.
Usually, the Gemini surfactant comprises at least two hydrophobic groups, and at least two ion radicals or polar group and one is base at interval.This dimeric structure can be symmetric (for example tail end is identical and head end identical) or asymmetric.In one or more embodiments, this Gemini surfactant comprises 3 or 4 tail ends.
The example of polar group comprises polyethers and sugar.The example of ion radical comprises cation and anion.The specific example of ion radical comprises ammonium, phosphate ester, sulfuric ester and carboxylate.In one or more embodiments, head end comprises one or more sulfate groups.
The example of base comprises polarity and non-polar group at interval.The example of Ji Teding comprises amide, short chain or long-chain methylene, stilbene, polyethers, aliphatic and aromatic group at interval.In one or more embodiments, base comprises the hydrocarbon chain methylene at interval.
In one or more embodiments, the Gemini surfactant can be represented with general synoptic diagram.
The selection that is used for Gemini surfactant of the present invention is based on one or more character, for example the quantity of the length of tail end, the degree of branching, the ionic kind of head end, counter ion type, head end (for example dimer, trimer, tetramer or the like), dissolubility (for example hydrophobic or hydrophilic), the length and the stability of basic molecule at interval of base at interval of base at interval.
In specific embodiment, the Gemini surfactant also comprises ion radical or polar group at uncombined each tail end.These ion radicals or polar group can be called terminal ion radical or terminal polar group.The example of suitable terminal ion radical comprises ammonium, phosphate ester, sulfuric ester and carboxylic acid ester groups.
In one or more embodiments, the Gemini surfactant can be represented with following general formula
Wherein each R is respectively the lipophilic chain, and m and n are respectively the integer of 1-about 500.The example of lipophilic chain comprises the organic group with about 26 carbon atoms of about 2-.
In a certain embodiment, the Gemini surfactant comprises ethylene coconut oleoyl amine PEG-15 hydrogen sulfate disodium.
In another embodiment, the Gemini surfactant can be represented with following general formula.
Each R wherein
1Comprise siloxane group or fluorizated organic group respectively, and m and n are respectively the integer of 1-about 500.In one or more specific embodiments, R ' comprises-(Si-O)
xSi (CH
2)
3Or-(CF
2)
zCH
3, x wherein is the integer of 1-about 26 and z is the integer of 1-about 26.
The Gemini surfactant also is disclosed in US6, and in 710,022, it incorporates this paper into as a reference.
This foaming surfactant comprises sulfuric ester in one or more specific embodiments.Usually, sulfuric ester comprises the sulfate group shown in the following general formula:
In a certain embodiment, this sulfuric ester comprises the sulfuric ester of polyethers, dihydroxylic alcohols or polyhydric alcohol.In a certain embodiment, this sulfuric ester comprises the sulfuric ester of aliphatic alcohol, can be by the prepared in reaction of aliphatic alcohol and chlorosulfonic acid or sulfur trioxide.
In one or more embodiments, sulfuric ester is selected the chain length of favorable properties based on aliphatic alcohol.In a certain embodiment, this foaming surfactant comprises sodium salt, diethanolamine, triethanolamine or the ammonium of sulfuric ester.
Example comprises polydimethylsiloxane PEG-7 sulfuric ester, PEG-4 coconut oleoyl amine sodium sulfate, PEG-4 lauramide sodium sulfate, coconut oil monoglyceride sodium sulfate, stearyl sodium chondroitin sulfate, sodium lauryl sulfate, sulfated oil acid glyceride and combination thereof.In a certain embodiment, this foaming surfactant comprises sodium lauryl sulfate.
In one or more specific embodiments, foaming surfactant comprises diester, for example contains two or more ester group groups.In specific embodiment, this foaming surfactant comprises the long-chain fat acid diesters.In a certain embodiment, this diester is the anion diester.
The example of anion diester comprises, stearyl sodium lactate, Shan Yu acyl group sodium lactate, oleoyl sodium lactate, cocoyl sodium lactate, caproyl sodium lactate, lauroyl lactic acid, myristoyl lactic acid and combination thereof.Other example comprises triethanolamine salt, diethanolamine salt, potassium salt, calcium salt or ammonium salt and the combination thereof of stearyl lactic acid, Shan Yu acyl group lactic acid, oleoyl lactic acid, cocoyl lactic acid, caproyl lactic acid, lauroyl lactic acid, myristoyl lactic acid.
In one or more embodiments, the foaming surfactant here comprises the anion diester, presses the total weight of alcoholic composition, and this foamable composite contains fluorosurfactant or the silicone surfactant of about at least 0.1 weight %.In another specific embodiment, the foaming surface activity here comprises the anion diester, and this foamable composite contains fluorosurfactant or the silicone surfactant of about at least 0.01 weight %.In another embodiment, the foaming surface activity here comprises the anion diester, and this foamable composite contains fluorosurfactant or the silicone surfactant of about at least 0.005 weight %.In specific embodiment, the foaming surface activity here comprises the anion diester, and this foamable composite does not contain fluorosurfactant or silicone surfactant.
In one or more embodiments, the foaming surfactant here comprises the anion diester, and this foamable composite also contains aliphatic alcohol as described below.In specific embodiment, the foaming surfactant here comprises the anion diester, and this foamable composite also contains one or more foamed promoters as described below.
In one or more specific embodiments, aliphatic alcohol is used to give this alcoholic composition foam characteristics.In one or more embodiments, this aliphatic alcohol contains about 34 carbon atoms of about 10-.This aliphatic alcohol can be straight or branched, and is saturated or unsaturated.The combination of two or more aliphatic alcohol also can be used.The example of aliphatic alcohol comprises, but be not limited to decanol, lauryl alcohol, tridecyl alcohol (auroleic alcohol), myristyl alcohol, nutmeg brain alcohol, palmityl alcohol, Palmitoleyl alcohol, stearyl alcohol, oleyl alcohol, inferior oleyl alcohol, linolenyl alcohol, arachidic alcohol, gaducene alcohol, behenyl alcohol, mustard alcohol, clupanodonic acid (clupanodinic alcohol), tetracosanol, hexacosanol, octacosanol, hentriacontanol, the pure and mild inearnatyl alcohol of dotriacontane.
In one or more embodiments, aliphatic alcohol contains about 28 carbon atoms of about 12-, in another embodiment, and about about 22 carbon atoms of 12-.In a certain embodiment, this aliphatic alcohol comprises lauryl alcohol, myristyl alcohol, palmityl alcohol, stearyl alcohol Huo behenyl alcohol and combination thereof.Lauryl alcohol make a comment or criticism often dodecanol, 1-dodecanol, dodecyl alcohol or lauryl alcohol.Myristyl alcohol often is meant 1-tetradecanol or tetradecanol.Palmityl alcohol often is meant 1-hexadecanol, spermol or soft lipidol.Stearyl alcohol often is meant 1-octadecanol, octadecanol or stearyl alcohol.Behenyl alcohol often is meant 1-tadenan, mountain Yu base alcohol.
There is no particular limitation so long as produce the amount of foamy effective dose foaming surfactant.In specific embodiment, producing foamy effective dose can change, and depends on the content of pure and mild other composition.Press the total weight of alcoholic composition, in one or more embodiments, alcoholic composition contains the foaming surfactant of about at least 0.05 weight %.In another embodiment, by the total weight of this alcoholic composition, alcoholic composition contains the foaming surfactant of about at least 0.06 weight %.In another embodiment, by the total weight of this alcoholic composition, alcoholic composition contains the foaming surfactant of about at least 0.07 weight %.
In one embodiment, by the total weight of this alcoholic composition, the amount of foaming surfactant is the about 40 weight % of about 0.05-.By the total weight of this alcoholic composition, in another embodiment, the amount of foaming surfactant is the about 30 weight % of about 0.1-, in another embodiment, and about about 10 weight % of 0.5-, in another embodiment, about about 5 weight % of 1-.Higher content can be predicted and also foam can be produced effectively.All wt about ingredients listed all is based on the active component level, does not therefore comprise that carrier maybe may be present in the side-product in the commercially available material, except as otherwise noted.
In specific embodiment,, be used to produce the aliphatic alcohol of the effective dose of foamy aliphatic alcohol for about at least 0.001 weight % by the total weight of this alcoholic composition.In another embodiment, by the total weight of this alcoholic composition, this alcoholic composition contains the aliphatic alcohol of about at least 0.005 weight %.In another embodiment, by the total weight of this alcoholic composition, this alcoholic composition contains the aliphatic alcohol of about at least 0.01 weight %.In another embodiment, by the total weight of this alcoholic composition, this alcoholic composition contains the aliphatic alcohol of about at least 0.02 weight %.
By the total weight of this alcoholic composition, in a certain embodiment, the amount of aliphatic alcohol is the about 10 weight % of about 0.001-, and in another program, about about 5 weight % of 0.002-.In another embodiment, by the total weight of this alcoholic composition, the amount of aliphatic alcohol is the about 4 weight % of about 0.01-.Higher content can be predicted and also foam can be effectively produced.
In specific embodiment, the foamable alcoholic composition of the present invention here contains can be applied in cleaning or the sterile products that the surface rinses out then, can use relatively large foaming surfactant.In these embodiments, by the total weight of said composition, the content of foaming surfactant can reach about 40 weight %.
In specific embodiment, when foamable composite contains the combination of two or more foaming surfactants, can obtain useful result.In a certain embodiment, foamable composite contains aforesaid aliphatic alcohol and anion diester.In another embodiment, foamable composite contains Gemini surfactant and sulfuric ester.In another embodiment, this foamable composite contains Gemini surfactant, sulfuric ester and anion diester.In one or more embodiments, this foamable composite contains Gemini surfactant and anion diester.In a certain embodiment, to count by weight percentage, the Gemini surfactant is about 0.6 with respect to the amount of diester: about 1.7: 1 of 1-.
In one or more embodiments, this foaming surfactant directly is added in the alcoholic composition.In another embodiment, this foaming surfactant is added in the alcoholic composition as solution or emulsion.In other words, this foaming surfactant can be pre-mixed with carrier and form foaming surfactant solution or emulsion, and condition is the foam performance that this carrier can not damage this alcoholic composition.The example of carrier comprises for example propylene glycol or ethylene glycol, ketone, straight chain and/or cyclic hydrocarbon, triglyceride, carbonate, organosilicon, alkene, ester acetate, benzoate, fatty acid ester, glyceride, ether, amide, Polyethylene Glycol and PEG/PPG copolymer, inorganic salt solution saline and composition thereof for example for example of water, alcohol, dihydroxylic alcohols.Be appreciated that when this foaming surfactant is formed foaming surfactant solution or emulsion by premix being added to the solution in this alcoholic composition or the amount of emulsion can select, thereby makes the consumption of foaming surfactant drop within the foregoing scope.
Foaming surfactant mixture, solution or emulsion have commercially available, for example available from the trade name of Sasol
Available from Tri-K Industries, the Biobase of Inc. and available from Ritamulse and the Ritafactant of RITA Corporation.
In specific embodiment, alcoholic composition of the present invention also contains at least a foamed promoter.In a certain embodiment, optional auto polymerization of this foamed promoter or oligomeric foam booster.In another embodiment, this foamed promoter is polymeric or non-polymeric.In a certain embodiment, this foamed promoter contains cationic oligomeric thing or polymer.
Polymeric foam booster comprises the polyquaternary ammonium salt polymer.Usually, the polyquaternary ammonium salt polymer is the special formulation of CTFA.The polyquaternary ammonium salt polymer is characterised in that and contains quaternary ammonium group.The limiting examples of polyquaternary ammonium salt comprises those that following table 1 is listed, comprises international specialty name cosmetic material (INCI) title and technology-specific title.
Table 1
INCI title technology-specific title
Polyquaternary ammonium salt
-X
-2 couples of (2-chloroethyl) ether and N, the polymer of N '-two [3-(dimethylamino) propyl group] urea
-4 hydroxyethyl-cellulose dimethyl diallyl ammonium chloride copolymers
-5 acrylamides and Beta-methyl acrylyl oxy-ethyl-trimethyl sulfate methyl ammonium copolymer
-6 poly-(dimethyl diallyl ammonium chlorides)
-7 dimethyl diallyl ammonium chlorides and acrylamide copolymer
The quaternised polymethylacrylic acid dimethylamino ethyl ester of-9 usefulness bromomethanes
The trimethyl ammonium product that-10 hydroxyethyl-celluloses and epoxide replace
-11 PVPN, N-dimethyl aminoethyl methacrylic acid copolymer dithyl sulfate solution
-14 N, N, N-trimethyl-2-[(2-methyl isophthalic acid-oxo-2-acrylic) the oxygen base] second ammonium Methylsulfate is equal
Polymers
-15 acrylamides-dimethylaminoethyl methacrylate monochloro methane copolymer
-16 3-methyl isophthalic acid-vinyl imidazole chloride-1-vinyl pyrrolidone chloride
The quaternary ammonium salt that-17 adipic acids and diethylamino propyl group amine and dichloroether reaction make
Quaternary ammonium salt that-18 adipic acids and the reaction of diethylamino propyl group amine make and dichloroether reaction
-19 by polyvinyl alcohol in 2, the quaternary ammonium salt of 3-epoxy propylamine prepared in reaction
-20 by polyethylene octadecyl ether and 2, the quaternary ammonium salt of 3-epoxy propylamine prepared in reaction
-22 acrylic acid-diallyldimethylammonium chloride (DADMAC) polymer
-22 acrylic acid-diallyldimethylammonium chloride (DADMAC) polymer
The epoxide reactive polyquaternary ammonium salt that-24 hydroxyethyl-celluloses and lauryl dimethyl ammonium replace
The block copolymer of-27 polyquaternary ammonium salt-2 and polyquaternary ammonium salt-17
-28 vinyl pyrrolidones/Methacrylamide oxypropyl trimethyl ammonium chloride
The quaternised propoxylation chitosan of-29 usefulness chloropropylene oxides
-30 N-carboxymethyl-N, N-dimethyl-2-((2-methyl isophthalic acid-oxo-2-acrylic) oxygen base) second ammonium inner salt,
Polymer with 2-methyl-2-acrylic acid methyl ester.
-31 2-propionitrile product and N, N-dimethylated propyl diethylenetriamine sulfuric ester
-32 propionic acid amide .s-dimethylaminoethyl methacrylate monochloro methane copolymer
-37 methacrylic acid trimethyl amino ethyl ester chloride polymer
-39 acrylic acid (AA) and acrylamide and diallyldimethylammonium chloride (DADMAC)
Polymer
-42 polyoxyethylene (dimethylimino) ethylidene-(dimethylimino) ethylene chlorination
Thing
-43 acrylamides, acryloyl group oxypropyl trimethyl ammonium chloride, amidopropyl acrylamide and
The monomeric copolymer of DMAPA
The monomeric polyquaternary ammonium salt of-44 vinyl pyrrolidones and quaternized imidazoline
The polyquaternary amine of-46 caprolactams, vinyl pyrrolidone and methyl ethylene imidazole salts
Salt
-47 quaternary ammonium chlorides-acrylic acid, acrylic acid methyl ester. and the chlorination of methacryl amido oxypropyl trimethyl
Ammonium
-48 methacryl ethyl betanins, 2-hydroxyethyl meth acrylate and methacryl ethyl three
The copolymer of ammonio methacrylate
-51 4-hydroxy-ns, N, N, 10-tetramethyl-9-oxo-3,5 is in 8-three oxygen-4-phospha 11-10-alkene-1-ammonium
Salt 4-oxide, with the polymer of 2-methyl-2-butyl acrylate
-53 acrylic acid (AA)/acrylamide/basic acrylamido oxypropyl trimethyl ammonium chloride (MAPTAC)
Copolymer
-54 aspartic acids and C
6-18Alkylamine and dimethylaminopropyl amine and monochloroacetic acid sodium reaction system
The polyquaternary ammonium salt that gets
-55 lauryl trimethyl ammonium chlorides, N, N-dimethyl-N-[3-[(2-methyl isophthalic acid-oxo-2-acrylic)
Aminopropyl]-1-dodecane ammonium chloride, with N-[3-(dimethylamino) propyl group]-2-methyl-2-propylene
The polymer of amide and l-vinyl-2-pyrrolidone
-56 aspartic acids and C
6-18Alkylamine and dimethylaminopropyl amine and monochloroacetic acid sodium reaction system
The polyquaternary ammonium salt that gets
-57 by Oleum Ricini isostearate succinate (q.v.) and Oleum Ricini amidopropyl trimethyl chlorine
Change the polyquaternary ammonium salt that ammonium (q.v.) monomer constitutes
-58 2-methyl acrylate, with 2, two [(2-propenyloxy group) methyl]-1-butanols and the divinyl of 2-
The polymer of benzene and N, N-dimethyl-1, the product of the quaternized chloromethane of 3-propane diamine
-59 polyester polyquaternary ammonium salt
-60 9-octadecenoic acid 12-hydroxyls-[(2-ethoxy) imino group] two-2,1-ethane two basic esters, with
5-isocyanide acyl-1-(isocyanide acyl methyl)-1,3, the polymer of 3-trimethyl-cyclohexane, with sulphuric acid two
The complex of ethyl ester
-62 butyl methacrylates, polyethylene glycol monomethyl ether methacrylate, ethylene glycol dimethyl third
Olefin(e) acid ester and 2-methacryl ethyl-trimethyl salmiac and 2,2 '-azo two (2-methyl-prop amidine)
The polyquaternary ammonium salt that the dihydrochloride reaction makes
-63 acrylamides, acrylic acid and ethyl-trimethyl salmiac acrylate copolymer
-65 by 2-methylacryoyloxyethyl phosphocholine, butyl methacrylate and Sodium methacrylate.
The polyquaternary ammonium salt that monomer constitutes
-68 vinyl pyrrolidones (VP), methacrylic acid amino (MAM) ethylene imidazoles (VI) and
The quaternised copolymer of quaternised ethylene imidazoles (QVI)
-69 contain caprolactam, vinyl pyrrolidone, dimethylaminopropyl metering system
Gathering of amide (DMAPA) and methacryl aminopropyl lauryl dimethyl ammonium chloride
Quaternary ammonium salt
-70 are made of also ethoxylation, propoxylation stearic amine with adipic acid and dilinoleic acid condensation
With the quaternised polyquaternary ammonium salt of dimethyl sulfate
-71 poly-(hydroxypropyl four (2-hydroxypropyl) ethylidene diammonium) chlorides
The polyquaternary ammonium salt of-72 hydroxyethyl-celluloses and the reaction of cocoa alkyl dimethyl ammonium substituted epoxide
-73 by oxypropyl trimethyl ammonium chloride acrylamide, ethyl-trimethyl salmiac methacrylate and
The polyquaternary ammonium salt that the DMAA monomer constitutes
-74 polyquaternary ammonium salt that constitute by dimethylaminopropyl Methacrylamide, acrylic acid
-75 starch hydroxypropyl-trimethyl ammonium chlorides (q.v.) and starch hydroxypropyl lauryl dimethyl ammonium chloride
Polyquaternary ammonium salt
In one or more embodiments, this polyquaternary ammonium salt polymer comprises quaternised copolymer or its mixture of hydrophobically modified of quaternised copolymer, vinyl pyrrolidone and the dimethylaminopropyl Methacrylamide of vinyl pyrrolidone and dimethylaminomethyl acrylate.
In one embodiment, this polyquaternary ammonium salt polymer has 1,000-5,000,000 molecular weight, in another embodiment, have about 2,500,000 the molecular weight of about 1500-, and in another other embodiment, have about 1,000, about 2,000,000 the molecular weight of 000-.
In one or more embodiments, this polyquaternary ammonium salt polymer can not have to give this alcoholic composition foaminess under the condition of other foaming surfactant.Just, in one or more embodiments, this polyquaternary ammonium salt polymer is as foaming surfactant or as foamed promoter.In another embodiment, this polyquaternary ammonium salt polymer can be used in combination with one or more other foaming surfactants.In these or other embodiment, this polyquaternary ammonium salt polymer comprises polyquaternary ammonium salt-11, polyquaternary ammonium salt-37 or its combination.
In one or more embodiments, the polyquaternary ammonium salt polymer plays the effect of foaming surfactant, and by the total weight of this alcoholic composition, the amount of this polyquaternary ammonium salt polymer is the about 5 weight % (active component) of about 0.1-.In another embodiment, by the total weight of this alcoholic composition, the amount of polyquaternary ammonium salt polymer is the about 4.5 weight % of about 0.4-, and in another other embodiment, by the total weight of this alcoholic composition, the amount of polyquaternary ammonium salt polymer is the about 4 weight % of about 0.5-.In another embodiment, the polyquaternary ammonium salt polymer is as foamed promoter, and is as described below as the suitable amount of this polyquaternary ammonium salt polymer of foamed promoter.
Other foamed promoter that is used to improve foam quality and/or stability comprises the trimer of caprolactam (VCL), vinyl pyrrolidone (VP) and dialkyl aminoalkyl acrylate, and this trimer comprises VP/ caprolactam/dimethylaminopropyl methacrylamide copolymer.And other foamed promoter comprises isobutene ./dimethylaminopropyl maleimide/ethoxylation maleimide/acid/maleic acid copolymers.The foamed promoter of these and other often is called film forming polymer.
Also have other foamed promoter to comprise acrylamide/ammonium acrylate copolymer; acrylamide/DMAPA acrylate/methoxyl group PEG methacrylate copolymer; acrylamide/sodium acryloyldimethyl taurate/acrylic copolymer; acrylamide propyl trimethyl ammonium chloride/acrylamide copolymer; acrylamide propyl trimethyl ammonium chloride/acrylate copolymer; acrylate/acetoacetoxy groups ethyl-methyl acrylate copolymer; acrylate/acrylamide copolymer; acrylate/ammonio methacrylate copolymer; acrylate/tert-butyl group acrylamide copolymer; acrylate copolymer; acrylate/C
1-2Succinate ester/hydroxy acrylate copolymer, acrylate/amine oxides methacrylate copolymer, acrylate/acrylic acid Lauryl Ester/stearyl acrylate base ester/amine oxides methacrylate copolymer, acrylate/octyl acrylamide copolymer, the end capped polydimethylsiloxanecopolymer copolymer of acrylate/octyl acrylamide/diphenyl amino, acrylate/poly-trimethylsiloxy group methacrylate copolymer, acrylate/stearyl acrylate base ester/amine oxides methacrylate copolymer, acrylate/trifluoro propyl methacrylate/poly-trimethylsiloxy group methacrylate copolymer, acrylate/VA copolymer, acrylate/VP copolymer, adipic acid/diethylenetriamines copolymer, adipic acid/dimethylamino hydroxypropyl diethylenetriamines copolymer, adipic acid/glycidyl diethylenetriamines copolymer, adipic acid/isophthalic acid/neopentyl glycol/trimethylolpropane copolymer, stearic acid allyl ester/VA copolymer, amino-ethyl acrylate phosphate ester/acrylate copolymer, amino-ethyl propane diol-acrylate/acrylamide copolymer, amino-ethyl propane diol-AMPD-acrylate/diacetone acrylamide copolymer, VA ammonium/acrylate copolymer, amino-terminated polydimethylsiloxane/silsesquioxane (silsesquioxane) copolymer, AMPD-acrylate/diacetone acrylamide copolymer, AMP-acrylate/allyl methacrylate copolymer, AMP-acrylate/acrylic acid C
1-18Arrcostab/C
1-18The alkyl acrylamide copolymer; AMP-acrylate/diacetone acrylamide copolymer; AMP-acrylate/dimethyl amino ethyl methacrylate copolymer; bacillus/Testa oryzae extract/soybean extract fermentation filter liquor; methacrylic acid docosyl ester/amine oxides methacrylate copolymer; polydimethylsiloxane/PEG-60 copolymer that dibutoxy is amino-terminated; the polydimethylsiloxanecopolymer copolymer that diisobutyl PEG-14/ is amino-terminated; the polydimethylsiloxanecopolymer copolymer that diisobutyl PEG-15/ is amino-terminated; butyl acrylate/methacrylic acid ethylhexyl ester copolymer; butyl acrylate/hydroxypropyl dimethione acrylate copolymer; the butyl ester of ethylene/MA copolymer; the butyl ester of PVM/MA copolymer; calcium/sodium PVM/MA copolymer; chitosan; lactic acid chitosan ester; corn starch/acrylamide/sodium acrylate copolymer; the dehydrogenation xanthan gum; diglycolamine/chloropropylene oxide/piperazine copolymer; the polydimethylsiloxane cross linked polymer; polydimethylsiloxane/silsesquioxane copolymer; the end capped polydimethylsiloxane of diphenyl amino; PVM/MA ethyl ester copolymer; methacrylate ethyl-trimethyl salmiac/ethoxy acrylamide copolymer; hydrolyzed wheat protein/PVP cross linked polymer; hydroxypropyl polydimethylsiloxane base propyl group acrylate copolymer; the hydroxypropyl-trimethyl ammonium chloride hydrolysed corn starch; isobutene ./ethyl maleimide/ethoxy maleimide copolymer; isobutene ./MA copolymer; isobutyl group methacrylate/trifluoroethyl methacrylate/dihydroxypropyl polydimethylsiloxane base acrylate copolymer; the isopropyl ester of PVM/MA copolymer; acrylic acid Lauryl Ester cross-linked copolymer; methacrylic acid Lauryl Ester/ethylene glycol dimethacrylate cross linked polymer; lauryl PEG-9 poly dimethyl silica ethyl polydimethylsiloxane; methacrylic acid/acrylic amide methyl propane sodium sulfate copolymer; acryloyl group ethyl betanin/acrylate copolymer; polydimethylsiloxane/silsesquioxane copolymer that methoxyl group is amino-terminated; methoxyl group PEG-114/ poly-epsilon-caprolactone; myristic acid/Palmic acid/stearic acid/ricinoleic acid/eicosane diacid glyceride; octyl acrylamide/acrylate/butyl amino-ethyl methacrylate copolymer; the PEG-800/ polyvinyl alcohol copolymer; PEG/PPG-25/25 polydimethylsiloxane/acrylate copolymer; the PEG-8/SMDI copolymer; polyacrylamide; polyacrylate-6; polyacrylate-8; polyacrylate-9; polyacrylate-15; polyacrylate-16; polyacrylate-17; polyacrylate-18; polyacrylate-19; poly-β-alanine/1,3-propanedicarboxylic acid cross linked polymer; poly-terephthalic acids butanediol ester; polyester-1; polyethyl acrylate; the Polyethylene Terephthalates; polyimides-1; polymethyl acyl group ethyl betanin; the polypentaerythritol terephthalate; poly-perfluor perhydrophenanthrene; polyquaternary ammonium salt-4/ hydroxypropyl starch copolymer; polyurethane-1; polyurethane-6; polyurethane-10; polyurethane-18; polyurethane-19; polyvinyl acetate; polyvinyl butyral resin; the polyethylene caprolactam; the polyethylene Methanamide; polyvinyl imidazole quinoline acetate; polyvinyl methyl ethermaleic anhydride; the butyl ester potassium salt of PVM/MA copolymer; the ethyl ester potassium salt of PVM/MA copolymer; PPG-70 polyglyceryl-10 ether; the PPG-12/SMDI copolymer; the PPG-51/SMDI copolymer; the PVM/MA copolymer; the PVP/VA/ itaconic acid copolymer; PVP/VA/ vinyl propionate ester copolymer; root nodule bacteria glue (rhizobiangum); rosin and crylic acid fat; Lac; organosilicon quaternary ammonium salt-16/ glycidoxy polydimethylsiloxane cross linked polymer; the butyl ester sodium salt of PVM/MA copolymer; the ethyl ester sodium salt of PVM/MA copolymer; sodium polyacrylate; poly-gamma-glutamic acid sodium; the soybean protein phthalate ester; sterculia urens's glue; terephthalic acid/isophthalic acid/sodiosulfoisophthalic acid/diol copolymer; trimethylolpropane triacrylate; trimethylsiloxy group silicyl carbamyl amylopectin; VA/ crotonates copolymer; VA/ crotonates/methacryloxy benzophenone-1 copolymer; VA/ crotonates/vinyl neodecanoate copolymer; VA/ crotonates/vinyl propionate ester copolymer; the VA/DBM copolymer; VA/ benzoic acid vinyl butyl ester/crotonates copolymer; vinylamine/ethenol copolymer; caprolactam/VP/ dimethyl amino ethyl methacrylate copolymer; VP/ acrylate/methacrylic acid Lauryl Ester copolymer; VP/ dimethyl amino ethyl methacrylate copolymer; the VP/DMAPA acrylate copolymer; VP/ hexadecene copolymer; VP/ Methacrylamide/vinyl imidazole copolymer; the VP/VA copolymer; VP/ caprolactam/DMAPA acrylate copolymer; the yeast cetylate; silicon-based polymer or resin be phenyl propyl dimethylsilyl bis esters of silicon acis for example; the trimethylsiloxy group esters of silicon acis; encircle penta siloxanes; the trimethylsiloxy group esters of silicon acis; two isostearoyl trimethylolpropane siloxy esters of silicon acis; vinyldimethicone cross linked polymer/mixture and alkyl 16/octadecyl polydimethylsiloxane cross linked polymer.
In one embodiment, this foamed promoter comprises VP/ caprolactam/dimethylaminopropyl methacrylamide copolymer of selling with trade name Aquaflex SF-40 or the isobutene. of selling with trade name Aquaflex XL-30/dimethylaminopropyl maleimide/ethoxylation maleimide/acid/maleic acid copolymers.In one or more embodiments, this foamed promoter also comprises available from the PVP/VA-630 of ISP (P/VA copolymer), available from the Collamino 25 of ArchPersonal Care (collagen amino acid), available from the Solu-Mar Elastin of Arch Personal Care (solvable elastin laminin) or available from the Amaranth S of Arch PersonalCare (cocoyl hydrolysis amaranth albumen sodium salt).
Useful foamed promoter also comprises the PVP/VA copolymer, for example available from the PCP/VA-630 of ISP, P/VA copolymer, collagen amino acid for example available from the Collamino 25 of Arch Personal Care, solvable elastin laminin for example available from the Solu-Mar Elastin of Arch Personal Care and cocoyl hydrolysis amaranth albumen sodium salt for example available from the Amaranth S of Arch Personal Care.
In one embodiment, by the total weight of this alcoholic composition, the content of this foamed promoter is the about 4 weight % (active component) of about 0.005-.In another embodiment, by the total weight of this alcoholic composition, the content of this foamed promoter is the about 1 weight % of about 0.01-, and in other embodiments, by the total weight of this alcoholic composition, the content of this foamed promoter is the about 0.2 weight % of about 0.02-.
In one embodiment, this foamed promoter directly is added in this alcoholic composition.In one or more other embodiments, this foamed promoter is added in the alcoholic composition as solution or emulsion.In other words, this foamed promoter can be pre-mixed with carrier and form foamed promoter solution or emulsion, and condition is the foam performance that this carrier can not damage this alcoholic composition.The example of carrier comprises for example propylene glycol or ethylene glycol, ketone, straight chain and/or cyclic hydrocarbon, triglyceride, carbonate, organosilicon, alkene, ester acetate, benzoate, fatty acid ester, glyceride, ether, amide, Polyethylene Glycol and PEG/PPG copolymer, inorganic salt solution saline and composition thereof for example for example of water, alcohol, dihydroxylic alcohols.Be appreciated that when this foamed promoter is formed foamed promoter solution or emulsion by premix, thereby be added to solution in this alcoholic composition or the amount of emulsion can select to make that the consumption of foamed promoter drops within the foregoing scope.
In one embodiment, the weight ratio of foaming surfactant and foamed promoter is about 3.5: about 14.5: 1 of 1-, and in another embodiment, the weight ratio of foaming surfactant and foamed promoter is about 8: about 11: 1 of 1-.
In specific embodiment, this foamed promoter has improved foam density and butyraceous foam is provided.This foam booster is used to improve foam by distinct methods.In one or more embodiments, this foam booster has also improved foamy quality, has for example increased the quantity of bubble and/or has reduced the size of bubble.
Alcoholic composition of the present invention also contains optional member widely, and condition is its foam performance or the foamy stability that can not damage this alcoholic composition.International cosmetic composition dictionary of CTFA in 2005 and handbook, the 11st edition, all all incorporate this paper into as a reference with 2004CTFA international procurement guide, wherein disclose a large amount of nonrestrictive used for cosmetic and the medicinal ingredient that are usually used in the skin nursing industry, it is applicable to compositions of the present invention.The non-limiting instance of the functional classification of composition is disclosed in these lists of references.The example of these functional classifications comprises: grinding agent; anti-acne agents; anticaking agent; antioxidant; binding agent; bio-additive; extender; chelating agen; chemical addition agent; coloring agent; the cosmetic astringent; the cosmetic Biocide; denaturant; medicinal astringent; emulsifying agent; external-use analgesic; film former; perfume composition; wetting agent; opacifier; plasticizer; antiseptic; propellant; Reducing agent; Porcelana Skin Bleaching Agent Porcelana; skin conditioning agent be (skin moistening; preserve moisture; miscellaneous and occlusion); Derma-Guard; solvent; foam booster; hydrotropic agent; solubilizing agent; suspending agent (non-surface-active agent); sunscreen; UV absorbers; antitack agent and thickening agent (aqueous and non-aqueous).The example of other functional classification that is used for material of the present invention known to those of ordinary skills comprises solubilizing agent, sequestering agent and keratolytic or the like.In one embodiment, this alcoholic composition also contains glycerol.
The cosurfactant that is included in this alcoholic composition is used for promoting or regulating foamy quality and character, smear and/or the sensation of end formulation when dry to be adjusted in, continue or the microbial action of permanent alcohol to provide, to dissolve other composition for example spice or sunscreen, with abirritate.Cosurfactant comprises, but be not limited to sulfosuccinate, amine oxide, polyoxyethylene (80) anhydrous sorbitol laurate, poly heteroside, alkanolamide, anhydrous sorbitol derivant, aliphatic alcohol ethyl oxide, quaternary ammonium compound, amido amine, sulfobetaines, different thiol hydrochlorate, sarcosinate, betanin, polysorbate and poly alkyl alcohol ethylene glycol.
The example of polysorbate comprises polysorbate-20, and it is also referred to as polyoxyethylene 20 sorbitan monolaurate; Polysorbate-40, it is also referred to as polyoxyethylene 20 sorbitan monopalmitate; Polysorbate-60, it is also referred to as polyoxyethylene 20 sorbitan monostearate; Polyoxyethylene Sorbitan Monooleate, it is also referred to as polyoxyethylene 20 sorbitan monooleate.Other example of polysorbate comprises polysorbate-21, polysorbate-61, polysorbate-65, polysorbate-81 and polysorbate-85.
There is no particular limitation for the consumption of auxiliary agent, only otherwise can damage the foam performance or the foamy stability of this alcoholic composition.In specific embodiment, by the total weight of this alcoholic composition, the content of one or more auxiliary agents is the about 2 weight % of about 0-in the foamable alcoholic composition.In other embodiment, by the total weight of this alcoholic composition and poly alkyl alcohol ethylene glycol, the content of one or more auxiliary agents is the about 1 weight % of about 0.1-in the foamable alcoholic composition.
In one or more embodiments, compositions of the present invention does not contain any foaming surfactant that is selected from Gemini surfactant, sulfuric acid ester surfactant, anion diester surfactant, polyquaternary ammonium salt polymer and aliphatic alcohol except those.In other embodiments, compositions of the present invention also contains one or more auxiliary foaming surfactants.Cosurfactant comprises fluorinated surfactant and siloxane polymer surfactant.Fluorinated surfactant and siloxane polymer foaming surfactant are disclosed in the U.S. Patent application the 11/438th, 664, and it incorporates this paper into as a reference.
Although can use propellant to produce stable foam, propellant is optional to be favourable.In specific embodiment, by the total weight of this alcoholic composition, the content of propellant is less than about 1000 ppm by weight.In one embodiment, this alcoholic composition is substantially devoid of propellant, for example hydrocarbon propellants.Be substantially devoid of the total weight that is meant by this alcoholic composition, the content of propellant is less than about 100 ppm by weight in this alcoholic composition.
In one embodiment, alcohol is added in the said composition as unique fungicide active ingredient, and presses the total weight of this alcoholic composition in this embodiment, and the content of assisting sterilisation composition is less than about 0.1 weight %.In other embodiments, said composition also contains the assisting sterilisation agent except alcohol.The example of assisting sterilisation agent includes, but not limited to triclosan, be also referred to as 5-chloro-2 (2,4-dichloro-phenoxy group) phenol and by Ciba-Geigy Corporation with trade name
Provide; Chloroxylenol is also referred to as 4-chloro-3, the 5-xylenols and by NiPa Labratories with trade name
MX or PX provide; Hexatidine is also referred to as 5-amino-1, two (2-the ethylhexyl)-5-methyl hexahydropyrimidines of 3-; Chlorhexidine salt comprises gluconic acid hibitane and N, N "-two (4-chlorophenyls)-3,12-diimino salt-2,4,11, the salt of 14-four azepine myristyl diamides; 2-bromo-2-nitropropane-1; 3-glycol, benzalkonium chloride; Cetylpyridinium chloride; Alkylbenzene methyl dimethoxy ammonium chloride; Iodine; Phenol derivatives, contain the povidone iodine of polyvinylpyrrolidone-iodine; Nipalgin; Hydantoin and derivant thereof comprise 2,4-imidazolinedione and 2, the derivant of 4-imidazoline and dihydroxymethyl-5,5-dimethyl hydantoin (being also referred to as DMDM Hydantoin or Gloriosa saperba L. pellet (glydant)); Phenyl phenol; 1-(3-chloro pi-allyl)-3,5, the 6-three azepines-muriatic cis-isomer of 1-nitrogen diamantane (obsolete), be also referred to as quatemium-15 and by Dow Chemical Company with trade name DOWCIL
TM2000 provide; N-(methylol)-N-(1, the two methylols-2 of 3-, 5-dioxy-4-imidazolidinyl)-N '-(methylol) urea; Benzethonium chloride; Methyl benzethonium chloride and composition thereof.When using, by the total weight of this alcoholic composition, the content of this assisting sterilisation agent is the about 1 weight % of about 0.1-.
Alcoholic composition of the present invention is also optional contains local widely medicinal active ingredient, and condition is its foam performance or the foamy stability that can not damage this alcoholic composition.The example of local medicinal active ingredient comprises salicylic acid, aspirin, cis-retinoic acid, trans retinoic acid, N-acetyl-L-cysteine, thioctic acid, Azelaic Acid, phytic acid, lysophosphatidic acid, tetracycline, ibuprofen, naproxen, acetyl aminophenol, hydrocortisone, resorcinol, phenoxyethanol, benzene oxygen propanol, benzene oxygen isopropyl alcohol, 2,4,4 '-three chloro-2 '-hydroxy diphenyl ether, 3,4,4 '-trichlorine diphenylurea, Octopirox (octopirox), 2-Phenylbenzimidazole-5-sulfonic acid, dihydroxy acetone, benzoyl peroxide, 2,4,4 '-three chloro-2-hydroxy diphenyl ethers, phenoxyethanol, benzene oxygen propanol, benzene oxygen isopropyl alcohol, phytic acid, thioctic acid, lisophosphotidic acid benoxaprofen, flurbiprofen, fenoprofen, fenbufen, ketoprofen, indoprofen, pirprofen, carprofen Evil promazine, pranoprofen, miroprofen tioxaprofen, suprofen, alminoprofen, tiaprofenic acid, fluprofen, the bucloxic acid, benzocaine, lignocaine, Bupivacaine, chloroprocaine, cinchocaine, etidocaine, mepivacaine, tetracaine, dyclonine, hexylcaine hydrochloride, procaine, cocaine, ketamine, pramoxine, phenol, dihydroxy acetone, tyrosine, tyrosine ethyl ester, phospho-DOPA, β-lactim medicine, the quinoline medicine, ciprofloxacin, norfloxacin, erythromycin, amikacin, doxycycline, capreomycin, hibitane, duomycin, oxytetracycline, clindamycin, ethambutol, esomedina, metronidazole, pentamidine, gentamycin, kanamycin, lincomycin, methacycline, hexamethylenamine, minocycline, neomycin, netilmicin, paromomycin, streptomycin, tobramycin, miconazole, the tetracycline hydrochloride, erythromycin, erythromycin zinc, erythromycin propionate lauryl sulfate, erythromycin stearate, amikacin sulfate, doxycycline hydrochloride, the sulphuric acid cirramycin, the gluconic acid hibitane, chlorhexidine hydrochloride, the Chlortetracycline, tetramycin hydrochloride, Luijiemycin Hydrochloride, ebutol, the hydrochloric acid metronidazole, the hydrochloric acid pentamidine, gentamycin sulfate, kanamycin sulfate, lincomycin hydrochloride, methacycline hydrochloride, methenamine hippu, hexamine mandelate, minocycline hydrochloride, polygynax, netilmicin sulfate, paromomycin sulfate, streptomycin sulfate, obracine, the hydrochloric acid miconazole, amantadine hydrochloride, PK-Merz (Merz), Octopirox, parachlorometaxylenol, nystatin, tineatonsurans is moved back, clotrimazole, p-methoxycinnamic acid 2-Octyl Nitrite, methoxyl group Cortex Cinnamomi monooctyl ester, para-aminobenzoic acid salt, para-aminobenzoic acid, 2-Phenylbenzimidazole-5-sulfonic acid, omeprazole is upright peaceful, oxybenzone, the salicylic acid height
Ester; ethylhexyl salicylate; 4; 4 '-methoxyl group-tert-butyl group dibenzoyl methane; 4-isopropyl diphenyl formoxyl methane; the 3-benzylidene camphor; 3-(4-methyl benzal) Camphora; titanium dioxide; silicon dioxide; ferrum oxide; 2; the 4-N of 4-dihydroxy benaophenonel; N-(2-ethylhexyl) methylamino benzoate; the 4-N of 4-hydroxy benzophenone acyl group methane; N-(2-ethylhexyl) methylamino benzoate; the 4-N of 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone; N-(2-ethylhexyl) methylamino benzoate; the 4-N of 4-(2-hydroxyl-oxethyl) dibenzoyl methane; N-(2-ethylhexyl) methylamino benzoate; tetracycline; ibuprofen; naproxen; acetaminophen; resorcinol; 3; 4,4 '-trichlorine diphenylurea; Octopirox; pharmaceutically useful salt and above-mentioned mixture.
In one or more embodiments, the surplus of this alcoholic composition comprises water and other suitable solvents.In the many embodiments of the present invention, this alcoholic composition volatilizees after use, and therefore flushing or the drying after having used said composition is all optional.These embodiments can be called to be kept here or the flushing free compositions.In one embodiment, one or more volatile organosilicon sills can be added to and be used for further helping evaporation in the prescription.It is also low that exemplary volatility organosilicon evaporates required heat than alcohol.In specific embodiment, the use of organosilicon sill can reduce the surface tension of fluid composition.This provides bigger contact surface.In one embodiment, this organosilicon sill is annular dimethyl polysiloxane, trimethylsiloxy group silicate or its combination for example, total weight by this alcoholic composition, also the concentration with the about 50 weight % of about 4 weight %-can be added in the prescription, being the about 35 weight % of about 5 weight %-in other embodiments, is the about 25 weight % of about 11 weight %-in another other embodiment.
In specific embodiment, the prescription that need rinse well after for example using, the surplus of this alcoholic composition comprises foaming surfactant.
Can prepare this alcoholic composition by simply being mixed together each component.The order of adding has no particular limits.In one embodiment, the skin degerming alcoholic composition is distributed to foaming surfactant in the alcohol, adds water and add foamed promoter then and stir up to this mixture uniform method preparation by comprising stirring with low speed or middling speed.
Foamable composite of the present invention can be with the dispenser therefor of any kind that is usually used in froth pulp.Favourable, though the method foaming of passing through the atomizing said composition that this foamable composite can be chosen wantonly, atomised product is optional for foaming.Can use any can be foamable alcoholic composition and air or the blended allotter of noble gas.Noble gas comprises the gas that does not react or damage foamable composite basically with foamable composite.The example of noble gas comprises nitrogen, argon, xenon, krypton gas, helium, neon and radon gas.In one embodiment, the employed allotter of this alcoholic composition is provided with foam pump, and its surrounding air or noble gas combine in mixing chamber with alcoholic composition and mixture is passed through mesh screen.In this and other embodiment, the viscosity of compositions is less than about 100mPas, in one embodiment, and less than about 50mPas, and in another embodiment, less than about 25mPas.
For practicality of the present invention is described, has prepared and tested the following example.Embodiment should not be considered as defining scope of the present invention.Claim will be used for determining scope of the present invention.
Embodiment
List in the one-tenth of measuring among Table I-VI by mixing and assign to prepare foaming formulation.Content is weight percentage.
Table I
| Embodiment 1 | Embodiment 2 | |
| Composition | ||
| Ethanol (SDA3C) | 60.00 | 60.00 |
| The proprietary aqueous mixture of 15-25% ethylene coconut oleoyl amine PEG-15 hydrogen sulfate disodium and 15-25% 2-Lauroyloxypropionic acid sodium | 0.08 | 0.20 |
| Polyquaternary ammonium salt-11 (20% aqueous solution) | 0.18 | |
| Water | To 100 | To 100 |
Table II
| Embodiment 3 | Embodiment 4 | |
| Composition | ||
| Ethanol (SDA3C) | 60.00 | 60.00 |
| The proprietary aqueous mixture of 15-25% ethylidene coconut oleoyl amine PEG-15 hydrogen sulfate disodium and 15-25% 2-Lauroyloxypropionic acid sodium | 0.08 | 0.60 |
| Water | 39.92 | 39.40 |
Table III
| Embodiment 5 | Embodiment 6 | Embodiment 7 | Embodiment 8 | |
| Composition | ||||
| Ethanol (SDA3C) | 60.00 | 60.18 | 60.18 | 60.00 |
| The proprietary aqueous mixture of 15-25% ethylidene coconut oleoyl amine PEG-15 hydrogen sulfate disodium and 15-25% 2-Lauroyloxypropionic acid sodium * | 0.75 | 0.75 | 0.75 | 0.75 |
| Polyquaternary ammonium salt-11 (20% aqueous solution) | 0.1 | |||
| Isobutene ./ethyl maleimide/ethoxy maleimide copolymer | 0.25 | |||
| The PVM/MA copolymer | 0.06 | |||
| Collagen amino acid (25% aqueous solution) | 1.00 | |||
| Water | 39.15 | 38.82 | 39.01 | 38.25 |
Table IV
| Embodiment 9 | Embodiment 10 | |
| Composition | ||
| Ethanol (SDA3C) | 59.00 | 60.00 |
| 2-Lauroyloxypropionic acid sodium | 1.00 | 1.00 |
| Polyquaternary ammonium salt-11 (20% aqueous solution) | 0.06 | |
| Water | 40.00 | 38.94 |
With the foaming of should filling a prescription of gas blowout foam pump.Foamy description is summarised in the Table VII.Embodiment 2 and 4-9 are described with respect to embodiment 1 and 3.Embodiment 10 is described with respect to embodiment 9.Embodiment 13 is described with respect to embodiment 11 and 12.Embodiment 17-19 is described with respect to embodiment 16.
Table VII
| The embodiment numbering | Foamy description |
| Embodiment 1 | Small amount of foam, flat, of short duration |
| Embodiment 2 | Bubble amt increase, so not flat, more fluffy |
| Embodiment 3 | Small amount of foam, flat, of short duration |
| Embodiment 4 | Have brighter bubble whiter foam, some is flat, the persistent period is longer |
| Embodiment 5 | Have brighter bubble whiter foam, some is flat, the persistent period is longer |
| Embodiment 6 | Foam is whiter, more fluffy but still of short duration |
| Embodiment 7 | Foam is whiter, more fluffy but still of short duration |
| Embodiment 8 | More fluffy, so not flat, bubble is brighter |
| Embodiment 9 | Whiter foam with bright bubble |
| Embodiment 10 | More fluffy foam with bright bubble |
| Embodiment 11 | White and fluffy, break rapidly |
| Embodiment 12 | Expand, break rapidly in vain |
| Embodiment 13 | White and fluffy, can not break rapidly, optimal volume |
| Embodiment 14 | White and fluffy, than other longer duration |
| Embodiment 15 | White and expand, bubble is tight |
| Embodiment 16 | Flat, of short duration foam |
| Embodiment 17 | The foam that improves does not break rapidly |
| Embodiment 18 | Slight fluffy foam |
| Embodiment 19 | Still flat but do not break rapidly |
| Embodiment 20 | In vain, volume is little |
| Embodiment 21 | The foam of good flash of light in vain, |
| Embodiment 22 | In vain, best among good volume, the embodiment 20-22 |
To those skilled in the art, not deviate from scope and spirit of the present invention be tangible to various modifications and changes.The illustrative embodiment that the present invention just in time is not confined to here to be enumerated.
Claims (17)
1. foamable composite, it contains:
By the total weight of this alcoholic composition, the C of about at least 40 weight %
1-4Alcohol; With
Be selected from Gemini surfactant, sulfuric ester, diester, C
10-34The foaming surfactant of aliphatic alcohol, polyquaternary ammonium salt polymer and combination thereof, prerequisite are that foaming surfactant contains diester, and this foamable composite also contains aliphatic alcohol or foamed promoter.
2. bactericidal composition, it contains:
By the total weight of this alcoholic composition, the C of about at least 50 weight %
1-4Alcohol; With
The approximately surfactant that is selected from Gemini surfactant, sulfuric ester, diester and polyquaternary ammonium salt polymer of the about 40 weight % of 0.05-, or the fatty alcohol surfactant of about about 10 weight % of 0.001-, or its combination; With
The foamed promoter that is selected from cationic oligomeric thing or polymer, collagen amino acid, amaranth albumen or solvable elastin laminin of about about 4 weight % of 0.005-.
3. be used to form the foamy method of pure formula, this method comprises:
Combination C
1-4Alcohol, be selected from Gemini surfactant, sulfuric ester, diester, C
10-34The foaming surfactant of aliphatic alcohol, polyquaternary ammonium salt polymer and combination thereof forms foamable alcoholic composition, and prerequisite is that foaming surfactant contains diester, and this foamable composite also contains aliphatic alcohol or foamed promoter;
Described alcoholic composition and air or noble gas mixed in mixing chamber form mixture; With
Described mixture is formed foam by mesh screen, and by the total weight of this alcoholic composition, foamable alcoholic composition described here contains the alcohol of about at least 40 weight %.
4. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein said foaming surfactant comprises the Gemini surfactant.
5. compositions as claimed in claim 4 or method, wherein said Gemini surfactant comprise ethylene coconut oleoyl amine PEG-15 hydrogen sulfate disodium.
6. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein said foaming surfactant comprises dimerization surface activity and diester, and to count by weight percentage the Gemini surfactant be about 0.6 with respect to the amount of diester: about 1.7: 1 of 1-.
7. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein said composition contains the foaming surfactant of the about 40 weight % of about 0.05-, by the total weight of said composition.
8. compositions as claimed in claim 1, wherein said compositions also contain cationic oligomeric body or polymer, collagen amino acid, amaranth albumen or solubility elastin laminin.
9. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein, total weight by this alcoholic composition, described foamable composite contains the alcohol that surpasses about 60 weight %, approximately the Gemini surfactant of the about 20 weight % of 0.1-and the approximately diester of the about 20 weight % of 0.1-.
10. compositions as claimed in claim 1 or 2; or method as claimed in claim 3, wherein said foaming surfactant comprises polydimethylsiloxane PEG-7 sulfuric ester, PEG-4 coconut oleoyl amine sodium sulfate, PEG-4 lauramide sodium sulfate, coconut oil monoglyceride sodium sulfate, stearyl sodium chondroitin sulfate, 2-Lauroyloxypropionic acid sodium, sulfated oil acid glyceride and combination thereof.
11. compositions as claimed in claim 1 or 2; or method as claimed in claim 3, wherein said foaming surfactant comprises stearyl sodium lactate Shan Yu acyl group sodium lactate; the oleoyl sodium lactate; the cocoyl sodium lactate; the caproyl sodium lactate; lauroyl lactic acid; myristoyl lactic acid; stearyl lactic acid triethanolamine Shan Yu acyl group lactic acid triethanolamine; oleoyl lactic acid triethanolamine; cocoyl lactic acid triethanolamine; caproyl lactic acid triethanolamine; stearyl lactic acid diethanolamine Shan Yu acyl group lactic acid diethanolamine; oleoyl lactic acid diethanolamine; cocoyl lactic acid diethanolamine; caproyl lactic acid diethanolamine; stearyl potassium lactate Shan Yu acyl group potassium lactate; the oleoyl potassium lactate; the cocoyl potassium lactate; the caproyl potassium lactate; stearyl calcium lactate Shan Yu acyl group calcium lactate; the oleoyl calcium lactate; the cocoyl calcium lactate; the caproyl calcium lactate; stearyl DL-Lactic acid ammonium salt. Shan Yu acyl group DL-Lactic acid ammonium salt.; the oleoyl DL-Lactic acid ammonium salt.; the cocoyl DL-Lactic acid ammonium salt.; caproyl DL-Lactic acid ammonium salt. and combination thereof.
12. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein said foamed promoter comprises quaternised copolymer or its mixture of polyquaternary ammonium salt, vinyl pyrrolidone and the quaternised copolymer of dimethylaminomethyl acrylate, vinyl pyrrolidone and dimethylaminopropyl Methacrylamide hydrophobically modified.
13. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein said foamed promoter comprises the tetramer or the isobutene ./dimethylaminopropyl maleimide/ethoxylation maleimide/acid/maleic acid copolymers of caprolactam VCL, vinyl pyrrolidone VP and dialkyl aminoalkyl acrylate.
14. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein the weight ratio of foaming surfactant and foamed promoter is about 3.5: about 14.5: 1 of 1-.
15. compositions as claimed in claim 1 or 2, or method as claimed in claim 3, wherein foaming surfactant comprises decanol, lauryl alcohol, tridecyl alcohol, myristyl alcohol, nutmeg brain alcohol, palmityl alcohol, Palmitoleyl alcohol, stearyl alcohol, oleyl alcohol, inferior oleyl alcohol, linolenyl alcohol, arachidic alcohol, gaducene alcohol, behenyl alcohol, mustard alcohol, clupanodonic acid, tetracosanol, hexacosanol, octacosanol, hentriacontanol, n-Dotriacontanol, inearnatyl alcohol or its mixture.
16. compositions as claimed in claim 15 or method, wherein said compositions also contain at least a auxiliary agent that is selected from polysorbate-20, polysorbate-21, polysorbate-40, polysorbate-60, polysorbate-61, polysorbate-65, Polyoxyethylene Sorbitan Monooleate, polysorbate-81 and polysorbate-85.
17. compositions as claimed in claim 15 or method, wherein, by the total weight of this alcoholic composition, the content of described aliphatic alcohol is the about 10 weight % of about 0.001-.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89124307P | 2007-02-23 | 2007-02-23 | |
| US60/891243 | 2007-02-23 | ||
| US60/980194 | 2007-10-16 | ||
| US12/032083 | 2008-02-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101310703A true CN101310703A (en) | 2008-11-26 |
Family
ID=40099665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101277355A Pending CN101310703A (en) | 2007-02-23 | 2008-02-22 | Foamable alcoholic composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101310703A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8866044B2 (en) | 2011-05-04 | 2014-10-21 | GM Global Technology Operations LLC | System and method for manufacturing magnesium body panels with improved corrosion resistance |
| CN104202980A (en) * | 2012-03-30 | 2014-12-10 | Gojo工业公司 | Antimicrobial alcohol foam compositions and methods of preparation |
| CN114767560A (en) * | 2022-05-20 | 2022-07-22 | 常州瑞昊环保科技有限公司 | Antibacterial composition and application thereof |
-
2008
- 2008-02-22 CN CNA2008101277355A patent/CN101310703A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8866044B2 (en) | 2011-05-04 | 2014-10-21 | GM Global Technology Operations LLC | System and method for manufacturing magnesium body panels with improved corrosion resistance |
| CN104202980A (en) * | 2012-03-30 | 2014-12-10 | Gojo工业公司 | Antimicrobial alcohol foam compositions and methods of preparation |
| US9943080B2 (en) | 2012-03-30 | 2018-04-17 | Gojo Industries, Inc. | Antimicrobial alcohol foam compositions and methods of preparation |
| CN114767560A (en) * | 2022-05-20 | 2022-07-22 | 常州瑞昊环保科技有限公司 | Antibacterial composition and application thereof |
| CN114767560B (en) * | 2022-05-20 | 2024-02-02 | 常州瑞昊环保科技有限公司 | Antibacterial composition and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8580860B2 (en) | Foamable alcoholic composition | |
| AU2006252070B2 (en) | Foamable alcoholic composition | |
| US11737457B2 (en) | Antimicrobial and foamable alcoholic compositions | |
| CA2621986A1 (en) | Foamable alcoholic composition | |
| EP2061310B1 (en) | Foamable sanitizing compositions | |
| US8309111B2 (en) | High alcohol content foaming compositions with silicone-based surfactants | |
| TW201340988A (en) | Foamable alcoholic compositions with skin benefits | |
| CN103732225A (en) | Antimicrobial compositions | |
| CN101310703A (en) | Foamable alcoholic composition | |
| AU2011224144C1 (en) | Foamable alcoholic composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1126124 Country of ref document: HK |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20081126 |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1126124 Country of ref document: HK |