CN101273916A - System and method for evaluating status of patient - Google Patents

System and method for evaluating status of patient Download PDF

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Publication number
CN101273916A
CN101273916A CNA200710101644XA CN200710101644A CN101273916A CN 101273916 A CN101273916 A CN 101273916A CN A200710101644X A CNA200710101644X A CN A200710101644XA CN 200710101644 A CN200710101644 A CN 200710101644A CN 101273916 A CN101273916 A CN 101273916A
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image
scoring
patient
mucosa
images
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CN101273916B (en
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马克·G.·吉尔利斯
布莱尔·刘易斯
莫迪凯·弗里施
德博拉·穆特
哈吉特·埃弗拉斯
埃迪·鲁迪克
艾伦·克莱文斯
塔尔·戴维森
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JIWEN IMAGING CO Ltd
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JIWEN IMAGING CO Ltd
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Abstract

The invention discloses a system and a method for combining image data of a patient, such as gastrointestinal images of the patient. The system and the method can assess the gastrointestinal conditions of a patient according to a plurality of embodiments of the invention, thus checking the mucosa treatment of preferential small intestine (SB) in the gastrointestinal tract of the patient, and/ or differentiating the different pathological conditions. The system and the method of the invention can provide a value or a score obtained by designating the score which is related to one or more preset parameters.

Description

The system and method for assess patient situation
The cross reference of related application
The application requires the priority of the 60/787th, No. 696 provisional application of the U.S. of submission on March 31st, 2006, and it all is combined in this by reference.
Technical field
The present invention relates to the system and method for assess patient situation.More specifically, the present invention relates to the system and method for struvite or mucosa infection in the assess patient gastrointestinal tract.
Background technology
Suffers from inflammatory bowel disease up to 100 ten thousand American according to estimates.Enteritis usually causes the pathological changes of mucosa or gastrointestinal (GI) road wall tissue.Inflammatory bowel disease refers generally to the chronic disease that two classes can cause enteritis: ulcerative colitis and Crow engler's disease (Crohn disease).Two kinds of modal symptoms of disease of ulcerative colitis and Crow engler's disease are diarrhoea and stomachache.
Because may there not be symptom, inflammatory bowel disease is difficult to diagnosis, even in the past few years his intestinal becomes from smoke into smother.When symptom occurring, they often demonstrate and the similar symptom of other disease, and this can make the doctor be difficult to make diagnosis.
Up to the present, inflammatory bowel disease is the symptom by doctor's record patient and manually provides an assessment based on the record symptom and check.Yet, always fully not related between symptom and patient's the actual state.
Summary of the invention
Embodiments of the invention provide a kind of view data in conjunction with the patient, and patient's gastrointestinal tract image for example is with the system and method for mucosa injury evaluation.
According to some embodiments of the present invention, a kind of system and method for assess patient gastrointestinal conditions is provided, with the mucosal treatment in the inspection patient's gastrointestinal tract, preferred small intestinal (SB) mucosa, and/or distinguish different pathological conditions.The invention provides a kind of value or scoring by specifying the mark relevant to obtain with one or more predefined parameters.
Other embodiments of the invention provide the scoring index of mucous membrane of small intestine situation.According to one embodiment of present invention, thus by calculating and using algorithm to draw scoring to one or more predefined parameters scorings.Usually, these parameter-definitions to the mucosa injury of stomach intestinal tissue.Can assess these parameters by observing the gastrointestinal image.Image can utilize for example endoscope, cryptomere endoscope or the shooting of other in-vivo imaging device.
Can conventionally use or as adventurous patient's (for example, Crow engler disease patient, through chemotherapeutic patient, NSAID carrier) follow up survey according to the method for the embodiment of the invention.Can also be used to checking the progress of treatment according to the method for the embodiment of the invention.Embodiments of the invention can also provide other purposes.
According to one embodiment of present invention, can gather a series of image that is examined inner chamber (for example, a part of gastrointestinal tract is as small intestinal (SB) or colon).For example, utilization can be swallowed the imaging capsule and can gather the gastrointestinal image and can be wirelessly transmitted to outside receptor/monitor.Image can download to work station and is used for further handling and being shown to the user then.This a series of image (can also be shown as one section film usually) can be divided into several fragments, and can be to each fragment or to marking from each segmental image subfamily.
According to another embodiment of the invention, the film of SB or gastrointestinal other parts can be divided into fragment based on the time schedule bar that for example offers film, the film of film such as cryptomere endoscope.The thumbnail by the image that photographs for example, the user can scrutiny fragment or a series of from segmental image, and can select the image that is used for marking.Each thumbnail can pull or otherwise import the cryptomere endoscope and observe software (for example, RAPID TMThe page of report group software).The page can comprise button, and it can be used to import the parameter value of several predefined parameters.Can be value of each parameter input of every width of cloth image (descriptive or digital) by the button click user, and software can be given the final scoring of weight and the selected image of calculating for parameter value.Final scoring can be presented to the user on workstation monitors.This scoring can be used for estimating the situation of SB mucosal tissue.This scoring can be used for evaluate patient situation and/or distinguish the different pathological situation.
The method of inflammatory disorders in a kind of assess patient gastrointestinal tract is provided according to one embodiment of present invention.Described method comprises step: provide a series of gastrointestinal tract image to the observer; A series of image segmentation is become fragment; Receive the scoring of piece image at least in each fragment, the relating to parameters of described scoring and at least one definition mucosa injury; And merge scoring to obtain final scoring.Described a series of images can be the image of small intestinal.According to an embodiment, the step of cutting apart a series of images comprises a series of images is divided into three fragments.According to an embodiment, described fragment is an isoplith.
The parameter of definition mucosa injury is: the fine hair outward appearance; Mucosa comes off; Ulcer; And the combination that organ is narrow or it is all or part of.
According to an embodiment, described method comprises that reception is selected from one group and comprises quantity, longitudinal extent, distribution pattern, shape, size and the one or more finger target values that traverse.
Described method can comprise and produces the thumbnail of piece image at least.Described method can comprise that generation comprises the report of thumbnail and final scoring.
Described method can comprise the final scoring of demonstration.
Provide according to some embodiments of the present invention and to be used for the gastrointestinal tract mucous system of assess patient.Described system can comprise the display of the piece image at least that shows the patient's gastrointestinal tract mucosa; And the scoring of acceptance pattern picture and based on the processor of the final scoring of image score calculation, wherein said image scoring is made up of the parameter value of definition mucosa situation.Described display can also comprise the time schedule bar that presentation video is consuming time.
According to an embodiment, described system comprises that the image stream with patient's gastrointestinal tract is divided into a plurality of segmental processors.Described fragment can be isometric.According to some embodiment, described system can comprise the processor that forms report, and described report comprises the combination of image scoring.Described report can also comprise the thumbnail of image.
According to some embodiment, the described parameter of definition mucosa situation can comprise the fine hair outward appearance; Mucosa comes off; Ulcer; And organ is narrow.According to some embodiment, described system comprises the capsule swallowed with imaging device; And receive from the receptor that can swallow capsular view data.
Further embodiment provides a kind of method of definite small intestinal situation according to the present invention, said method comprising the steps of: a plurality of small intestinal images are provided; In image, discern mucosa injury, thereby identification comprises the image of damage; And determine degree of injury based on the image that the minority in the multiple image comprises damage.Mucosa injury can be that organ injury (for example ulcer) and described degree can be sizes.Described degree can also comprise shape or other key element.
Determine final scoring according to an embodiment based on degree of injury.
Description of drawings
To understand and understand the present invention more fully by detailed description below in conjunction with accompanying drawing, wherein:
Fig. 1 is the sketch map according to the imaging system of the embodiment of the invention;
Fig. 2 is the flow chart according to the method for embodiments of the invention assess patient gastrointestinal conditions;
Fig. 3 is the flow chart according to the method for inflammatory disorders in the embodiments of the invention assessment mucosal tissue;
Fig. 4 is the screen display according to the monitor of the embodiment of the invention; And
Fig. 5 is the screen display according to the exemplary scoring report template of the embodiment of the invention.
The specific embodiment
In the following description various aspects of the present invention will be described.For the purpose of explaining, concrete structure and details have been provided so that complete understanding the present invention.Yet, conspicuous for those of ordinary skills, the detail that here proposes not, the present invention also can implement.And hard to understand in order not make the present invention, well-known feature is omitted or simplifies.
Unless special provision in addition, obviously be to be appreciated that the term that adopts in the discussion of whole description in the following discussion, for example " processing ", " calculating ", " storage ", " determining " or similarly, be meant the action and/or the processing of computer or computing system or similar electronic computing device, other class likelihood data that the physical quantity in (for example electronics) date processing that it represents the depositor of computing system and/or the physical quantity in the memorizer and/or memorizer, depositor or out of Memory storage, transmission or the display device that converts computing system to is represented.
Here, embodiments of the invention can comprise the device of executable operations.This device can make up especially according to required purposes, perhaps can comprise by the computer program selectivity that is stored in the computer using the general purpose computer that activates or reequip.This computer program can be stored in the computer-readable storage media, disk such as but not limited to any type comprises floppy disk, CD, CD-ROM, magneto-optic disk, read only memory (ROM), random-access memory (ram), EPROM (EPROM), Electrically Erasable Read Only Memory (EEPROM), magnetic or light-card, perhaps is suitable for the medium that store electrons is instructed and can be connected to any other type of computer system bus.
The processing of Ti Chuing here is inevitable relevant with any concrete computer or other device with demonstration.Various general-purpose systems can be used jointly with the program that meets teaching of the present invention, perhaps are more easily to set up a more special-purpose device to carry out desired method.Be to be appreciated that various program languages can be used for realizing teaching of the present invention described here.
With reference to Fig. 1, it has represented the sketch map of imaging system according to an embodiment of the invention.In the exemplary embodiment, described system can comprise having the equipment 40 in the body of imager 46 of photographic images that is used for, for example capsule or other suitable device, be used for illuminating human intracavity's light source 42, and be used for receiving for example emitter 41 of image and possible out of Memory of data to receiving equipment emission or from receiving equipment.Equipment 40 can not be capsule in optional embodiment; For example, equipment 40 can be endoscope or other in-vivo imaging device.The optical system that for example comprises one or more lens can help reflected light is focused on the imager 46.Equipment 40 can insert in patient's body by for example swallowing, and preferably passes patient's gastrointestinal tract.In certain embodiments, described equipment and image capturing apparatus are similar to the United States Patent (USP) 5,604 that licensed to people such as Iddan on March 7th, 2006,531 or United States Patent (USP) 7, the embodiment that describes in 009,634, the two all transfers the application's commonly-assigned us and is combined in here by reference.In optional embodiment, can use other image picking-up apparatus with other structure and other image capturing apparatus with other structure.
Preferably, picture receiver 12 is positioned at the external one or more positions of patient, and picture receiver 12 preferably includes antenna or aerial array, picture receiver memory element 16, data processor 14, data processor memory element 19 and is used to show the image of 40 records of equipment especially and the image monitor 18 of out of Memory.Preferred image receptor 12 and picture receiver memory element 16 volumes are little, easy to carry, and may be worn on one's body the patient during document image.Data processor memory element 19 can comprise image data base 10, parameter database 20, as the condition of illness parameter, scoring or other data base, data that other data base can comprise such as capsular endoscope standardization term (CEST), CEST can be used to prepare the report of assess patient situation, for example scoring report.Although can use other structure, but preference data processor 14, data processor memory element 19 and monitor 18 are parts of PC or work station, it can comprise assembly such as processor 14, memorizer, disc driver and input/output unit, and described system and method for the present invention can be finished in various suitable processing systems.Data base 20 can and can store the information that is different from condition of illness or CEST in other position, and for example, data base 20 can pass through for example the Internet remote access of network.
Data processor 14 can comprise any suitable data processor, for example microprocessor, multiprocessor, accelerator card or any other serial or parallel high-performance data processor.Image monitor 18 can be that computer screen, conventional video display units or any other can provide the equipment of image or other data.
Preferably, imager 46 is appropriate C MOS photographing units, for example the cmos imaging instrument of " photographing unit on the sheet " type.In optional embodiment, imager 46 can be a miscellaneous equipment, for example is CCD.Can use the imager of 320 * 320 pixels according to some embodiment.Pixel Dimensions can be between the 5-6 micron.Can cooperate with a lenticule according to each pixel of some embodiment.Light source 42 for example can be one or more light emitting diodes or other suitable light source.
In operation, imager 46 can photographic images and can be sent the data of representative image to emitter 41, and emitter for example can use that electromagnetic wave is transferred to picture receiver 12 with image.Picture receiver 12 can be sent to view data picture receiver memory element 16.After the data acquisition certain hour, the view data that is stored in the memory element 16 can send to data processor 14 or data processor memory element 19.For example, can take off picture receiver memory element 16, and,, be connected to the PC or the work station that comprise data processor 14 and data processor memory element 19 as the serial or parallel interface of known configurations by the normal data link from patient body.View data can be transferred to image data base 10 the data processor memory element 19 from picture receiver memory element 16 then.Data processor 14 can analytical data and institute's analytical data is offered image monitor 18, and the sanitarian can perspective image data there.Data processor 14 can move the software with the operation of function software such as operating system and device driver control data processor 14.Preferably, the software of control data processor 14 comprises the coding of writing with C Plus Plus or possible other Languages, but can finish with various known methods.Needn't use intermediate receiver 12 in other embodiments.
Be included in data base 20 in the memory element 19 and for example can be included in the computer-readable storage media, comprise floppy disk, CD, CD-ROM, magneto-optic disk, read only memory (ROM), random-access memory (ram), EPROM (EPROM), Electrically Erasable Read Only Memory (EEPROM), magnetic or light-card sheet or any other type media that is suitable for storing such as but not limited to the disk of any type.The condition of illness data base can comprise for example CEST and/or known condition of illness or case, known disease, tumor and particular tissues.Known condition of illness can comprise polyp, pathological changes, hemorrhage or the like.Data base 20 can also comprise the out of Memory image-related with every, for example appraisal result, scoring formula, subject information, key word, description, complete medical diagnosis, relevant case, article or image, for example image of closed area, condition of illness image or any out of Memory.In other embodiments, other reference data for example with the tabulation of mucosa injury related data, can be included in the graphical analysis scoring and the preparation diagnosis report that are used among the data base 20 based on imaging device 40 shootings.
Other position, processing or analysis can ad infinitum be stored, be transferred to the view data of gathering and storing.The sanitarian can be according to the parameter scores of one or more image to several predetermined gastrointestinal tract such as SB.System can provide for example finally scoring of information, the situation of the mucosal tissue of indicated number in image.According to some embodiment, system can provide the information about patient's mucosal tissue and/or patient's treatment situation.When using at first by data processor memory element 19 image data, then with transfer of data during to the system of data processor 14, view data can not Real Time Observation, other structure permission Real Time Observation.
Image monitor 18 can display image data, preferably with the form of static and dynamic menu, can show out of Memory in addition.In one exemplary embodiment, this additional information can include but not limited to show the timeline of every width of cloth image time spent, confirm condition of illness such as hemorrhage image, swallow the position of capsule in patient's abdominal part etc.In one exemplary embodiment, various information are presented in the window.Can use a plurality of monitor display images and other data.
Gather a series of still images when preferably, gastrointestinal tract passes in the in-vivo imaging system.Subsequent picture can be rendered as and for example pass gastrointestinal image stream or film.The in-vivo imaging instrument system can be gathered mass data because equipment 40 can pass gastrointestinal tract with several hrs in the body, and can be with for example speed document image of per second two width of cloth images, outcome record several thousand width of cloth images.Image record speed (or picture photographing speed) can change.
With reference to Fig. 2, it has described the flow chart of the method for assess patient gastrointestinal conditions according to one embodiment of present invention.In step 200, the user for example can observe from endoscope or a series of images that receives from in-vivo imaging device such as equipment 40, for example gastrointestinal tract image.Image can be stored in private database, thereby maybe can send out Real Time Observation from equipment in the intravital body of patient.The user can observe image on monitor, monitor can be the part of PC, work station, PDA etc.In step 210, the user can select the interested image of one or more or select the part of piece image from a series of images.Based on the anatomical area of pictorial display, a series of images can be divided into a plurality of parts.Selection can be finished by operating user interface, for example keyboard, control stick, mouse or any other input equipment.The image that the user selectes can show on special display screen.In step 220, the user can specify value descriptive or numeral, value and one or several predetermined parameter correlation to image.In one embodiment, the user can give several parameter assigned tags or marks of pre-determining, and these parameters can be selected from data base 20.
In one embodiment, the user can send order by for example data processor 14 of user interface 30 in data processor memory element 19, and user interface can be keyboard, control stick, mouse or other suitable input/output unit.Based on specified Several Parameters labelling of user or mark, data processor 14 can move any suitable score calculation or software for calculation or method and determine final scoring.The software that is used for marking, algorithm or method can be based on numeral, the semantic calculating of logic OR, and calculating relates to parameter value, predetermined data base's constant and weight, term and formula.
The process of report, classification and scoring can realize with different pattern, and for example, the medical science that systematic search image data base 10 is searched the condition of illness of coupling and can be calculated the patient automatically in automatic mode is marked or classification results.In semi-automatic pattern for image or partial images perhaps many images sanitarian for example input, labelling or fill in piece image or the analysis form of the part of piece image or multiple image; for example scoring report; output can receive diagnosis, classification or the appraisal result of selected picture then; it can comprise usually every width of cloth image is provided fractional summation; according to an embodiment is weighted sum, or other combination.In manual mode, the sanitarian can be according to the one or more values that pre-determine parameter of one or more image observation input, and can require appraisal result based on the value of input.In one embodiment of the invention, the sanitarian can confirm diagnosis or scoring report, to understand status of patient better.Can use other pattern or the method for mating.
Appraisal result can use various suitable methods to show, for example according to the results list of image correlation proper alignment, show relevant final scoring or any other appropriate method of image of selecting in the image stream with shooting.Appraisal result can comprise the score of pictorial display, as progress bar, scale, numerical value or any alternate manner.
Referring now to Fig. 3, it has described the flow chart of assessing the method for struvite pathological changes in the mucosal tissue according to one embodiment of present invention.In step 300, the user can observe a series of images, for example the gastrointestinal tract image that receives from endoscope, capsular endoscope or in-vivo imaging device such as equipment 40.Image can be stored in the private database, or can be on one side in the intravital body of patient device transmission Real Time Observation on one side.The user can observe image on monitor, monitor can be the part of PC, work station, PDA etc.A series of gastrointestinal tract images or a part of gastrointestinal tract in step 310 (for example, SB or colon) image can be divided into several fragments.For example, a series of in certain embodiments small intestinal images can be divided into three fragments (three sections) based on the time schedule bar that offers the imaging device film.According to another embodiment, image can be cut apart according to anatomical area.In step 320, the user can check all images in each fragment or a few width of cloth images of picking out from each fragment.According to some embodiment, the parameter for example size of the longitudinal length of pathological changes or pathological changes (for example ulcer) can be determined based on the picture of lesions showed or the sum of image.In step 330, the user can select the interested image of one or more or select the part of image from fragment or from a series of images.For example, the user can select single image and produce the thumbnail of this image from each fragment.Selected and generation thumbnail can be finished by operating user interface, for example keyboard, control stick, mouse or any other input equipment.The image of interest that the user selects can show on the concrete display screen of monitor.In step 340, the user can specify and several labelling or marks that pre-determine relating to parameters, and these parameters define mucosa injury usually, can select from data base 20.
In another embodiment, by importing one or more and interested image relevant interested word or key word, the user can search for its one or several concrete parameter of wishing scoring.Occurrence can comprise the very relevant parameter of one or more and selected interested image.Can use any other search and method.Search can be used local data base, for example is arranged in the data base of work station, PC, perhaps uses remote data base, for example the Internet or the special health data base that shares with other hospital or medical institutions.
According to some embodiments of the present invention, at the report section of the display screen of capsule endoscope system, the user can pull the thumbnail of interested image or interested image or move to the page of for example marking.In certain embodiments, the page for example mark output the page can comprise and each parameter that will assess and the corresponding button of parameter value.The user can or specify a value to each parameter setting labelling of every width of cloth image, and can use algorithm or a series of medical science formula to increase or composite marking up to drawing final scoring.According to another embodiment, the user selects to be reflected in the descriptive term of the condition of illness feature of finding in the thumbnail.Software program is then based on selected descriptive term assigned tags.
In certain embodiments, parameter can define the mucosa injury of SB tissue.According to an embodiment parameter can be: 1. fine hair outward appearance; 2. mucosa come off (no fine hair); 3. ulcer; 4. organ narrow (the gastrointestinal tract inner chamber dwindles).Each of these parameters can receive labelling, and final scoring derives from the specified all or part of value of each parameter.Final scoring can comprise the summation of whole labellings.For example, final scoring is approximately 9 and can indicates ' not having disease ', final scoring is 17 can indicate ' minor ailment ', final scoring is 33 can indicate ' not having the clinical manifestation disease ', and final scoring is that 130 can to indicate ' moderate disease ' and final scoring be 179 can indicate the patient to suffer from ' serious disease '.Scoring can conventional be carried out or to adventurous patient's (for example, Crow engler disease patient, through chemotherapeutic patient, NSAID carrier) follow up survey.Scoring can also for example be used to check the mucosa reparation in response to treatment.
Be based on three variablees according to other embodiment coefficient of marking: fine hair outward appearance, ulcer and organ are narrow.According to this embodiment,, per three minutes positions are analyzed by being divided into three moieties (three fens positions) the capsule time of passing.According to an embodiment, ulcer can be defined as mucosa and sport white or xanchromatic base portion and red or peach neck ring.The ulcer size can comprise its neck ring based on whole pathological changes, and can measure according to the capsule amount of images relevant with pathological changes.Typical ulcer size can be based in each maximum ulcer of being seen in the position in three minutes.
According to some embodiment, the fine hair outward appearance can be defined as edema when the fine hair width is equal to or greater than height of naps.
According to an embodiment, pathological changes quantity is defined as one, minority (2-7 pathological changes) or a plurality of (8 or above pathological changes).The small intestinal fragment length twines and can define with the percentage ratio of special three minutes positions that comprise mucosa infection.For example, 10% and the long segment that short-movie section can be defined as three fens positions can be defined as the 11-50% of three fens positions.
According to an embodiment, irrelevant with single three minutes positions, based on the whole sample of observed image the narrow mark of organ is assessed.
According to an embodiment, produce final scoring by scoring and the narrow scoring of increase organ that merges each three fens position.For example, can generation as described below finally mark: increase (fine hair parameter x scope x descriptor)+(ulcer parameter x scope x size) and then increase (can narrow several x ulcer x pass (be passed narrow definite by capsule)) for each three fens position.
According to some embodiment, final scoring adds the narrow scoring of organ based on position scoring in the highest three minutes.
According to some embodiment, the scoring of clinical unconspicuous disease and minor ailment is 0-135, and the scoring of slight and moderate disease is 135-790, and the serious disease scoring is more than 790.
Referring now to Fig. 4, represented screen display according to an embodiment of the invention and/or graphical interface of user, it is used to prepare a report as the scoring report, and/or assesses several quantity or marks that pre-determine parameter.Screen display 400 can comprise the simple and clear pictorial display 420 of in-vivo image stream, for example color fringe.Usually, pictorial display 420 can be to be shown as in the other fixedly demonstration of the dynamic demonstration of image stream 410.In other embodiments of the invention, pictorial display 420 can separately show.Pictorial display 420 can comprise a series of colors, a series of colored region or a series of pattern, image detail, image or pixel groups (for example a series of stripeds 422 or colored region, arrange to form bigger striped or rectangular area), the component in every kind of color in the series 422 and the original data stream or the component group is associated and/or correspondingly wherein.For example, each color fringe 422 can be corresponding with image or the image sets from data flow 410.Can use elementary area (as pixel, block etc.) rather than striped, and elementary area can change various aspects (for example pattern, size, width, brightness, activeness etc.) rather than color.An elementary area (for example striped 422) can be represented one or more unit (for example image frame) in original data stream.In one embodiment of the invention, order directional pattern shows that striped in 420 can make image stream advance to picture corresponding to striped.
In one embodiment, along with corresponding in fact data show in the data flow 410 (for example video), labelling or indicator 450 can be passed or advance along pictorial display 420 simultaneously, with the corresponding relation of indication between pictorial display 420 and data flow 410.According to other embodiment, can use sound, figure and other suitable form presentation graphic to show.
When image stream 410 was presented on the screen 400, indicator 450 for example cursor can be advanced along time schedule bar 430 and pictorial display 420.In one embodiment, in display, can comprise control knob 440, can allow for example F.F. of user, refund, stop playing image stream 410 or get back to the beginning or end of image stream 410.In other embodiments of the invention,, for example jump to area-of-interest by revising the starting position of dynamic demonstration, by the position of moving indicator 450 with mouse or other indicating equipment, the user can control data the demonstration of stream 410.
According to some embodiments of the present invention, the inner chamber of checking, for example gastrointestinal tract or SB more specifically can be by aircraft pursuit course 460 expressions, curve can be divided into several fragments, for example three section 460 ', 460 " and 460 ' " thereby can locate damaged tissues or pathological changes better.In addition, because some can have the reveal any symptoms of fritter with mucosa injury diseases associated (for example Crow engler disease), therefore need the whole length of detection inner chamber.It is also very important that what degree understanding is damaged to along inner chamber.In certain embodiments, checked inner chamber can be divided into interval 430 ', 430 based on time schedule bar 430 " and 430 ' ".For example, interval 430 ' can be indicated one of three sections 460 ', interval 430 " can indicate one of three sections 460 ", interval 430 ' " can indicate one of three sections 460 ' ".According to some embodiment, interval 430 ', 430 " and 430 ' " be equal-sized.
Shown in Fig. 2 and 3, obtain report/scoring button 480 and can allow the user to start scoring procedures.According to some embodiments of the present invention, user or sanitarian can be from promptly three section 460 ', 460 of fragments " and 460 ' " selection one or more image for example mark and report to be included in report.Can indicate the specific picture of having selected by highlighted show tags 470.Click or indicate " obtaining report/scoring " button 480 can make the user advance to the new screen of the Show Button, this button can also provide for example template of scoring report for preparing a report for the user corresponding to the parameter that will assess.
In other embodiments of the invention, user and/or sanitarian can insert indicator or labelling such as thumbnail so that find these positions in the future easily in mark position.For example, labelling 470 can be indicated along time bar 420 and can be obtained the candidate image picture.
With reference to Fig. 5, it has represented the screen display 500 of exemplary scoring report template according to some embodiments of the invention.Screen display 500 for example first three section scoring report of report template of can representing to mark.Screen display 500 can comprise one or more parameters that can draw from the gastrointestinal tract image.These parameters define the mucosa injury of stomach intestinal tissue usually.According to one embodiment of present invention, parameter can be a fine hair outward appearance 510; Mucosa (the no fine hair) 520 that comes off; Ulcer 530; And organ narrow 540.Each parameter can comprise that a plurality of users can specify fractional descriptive characteristics to it, for example quantity 532, longitudinal extent 534, distribution pattern 536, shape 538 and size 539.For example, the user can be by clicking button 531,533 and 535 one of them shape 538 setting labelling or scoring to ulcer 530.
According to some embodiments of the present invention, the user can see the accumulative total overall score of following progress on independent UI screen.In certain embodiments, after scoring was finished dealing with, for example after the user finished scoring report and fills in, final scoring can be shown to the user.
After here explaining and having described some feature of the present invention, those of ordinary skills can make many modifications, replacement, change and behavior of equal value.Therefore, should be appreciated that appended claims covers all these class modifications and variations in the spirit of the present invention.

Claims (21)

1. method that is evaluated at struvite pathological changes in the patient's gastrointestinal tract, described method comprises:
Provide a series of gastrointestinal tract image to the observer;
A series of image segmentation is become fragment;
From each fragment, receive the scoring of piece image at least, the relating to parameters of described scoring and at least one definition mucosa injury; And
Merge scoring to obtain final scoring.
2. according to the process of claim 1 wherein that described a series of images comprises the image of small intestinal.
3. according to the process of claim 1 wherein that the described step of cutting apart a series of images comprises a series of images is divided into three fragments.
4. according to the process of claim 1 wherein that the described step of cutting apart a series of images comprises a series of images is divided into isoplith.
According to the process of claim 1 wherein the parameter of described definition mucosa injury be selected from comprise that fine hair outward appearance, mucosa come off, ulcer, and narrow or its all or part of combination of organ.
6. according to the process of claim 1 wherein that described reception scoring comprises the numerical value that receives the one or more factors that are used to be selected from quantity, longitudinal extent, distribution pattern, shape, size and traverse.
7. according to the method for claim 1, comprise producing the thumbnail of piece image at least.
8. according to the method for claim 7, comprise producing report that described report comprises thumbnail and final scoring.
9. according to the method for claim 1, comprise showing final scoring.
10. system that assess patient is gastrointestinal tract mucous, described system comprises:
The display that shows the piece image at least of patient's gastrointestinal tract mucosa; And
Scoring of acceptance pattern picture and the processor of finally marking based on the image score calculation;
Wherein said image scoring is made up of the parameter value of definition mucosa situation.
11. according to the system of claim 10, wherein said display also comprises the time schedule bar that presentation video is consuming time.
12., be divided into a plurality of segmental processors comprising image stream with patient's gastrointestinal tract according to the system of claim 10.
13. according to the system of claim 12, wherein said fragment is isometric.
14. according to the system of claim 10, comprising a processor that forms report, described report comprises the combination of image scoring.
15. according to the system of claim 14, wherein said report comprises the thumbnail of image.
16. according to the system of claim 10, the described parameter that wherein defines the mucosa situation is selected from: fine hair outward appearance, mucosa come off, ulcer, and organ narrow.
17. according to the system of claim 10, comprising:
The capsule swallowed with imaging device; And
Reception is from the receptor that can swallow capsular view data.
18. the method for a definite small intestinal situation, described method comprises:
Several small intestinal images are provided;
Mucosa injury in the recognition image, thus identification comprises the image of damage;
Determine damage range based on the quantity that comprises the image of damage in many width of cloth images.
19. according to the method for claim 18, wherein said mucosa injury is an organ injury.
20. according to the method for claim 18, wherein said scope refers to size.
21. according to the method for claim 18, comprising determine final scoring based on damage range.
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