CN101264163A - Chinese medicine powder for treating headache - Google Patents

Abstract

The invention discloses a Chinese herbal medicine powder for curing headache, comprising ten Chinese herbal medicines as the material: angelica sinensis, rhizoma ligustici wallichii, uncaria, prepared rhizome of rehmanniae, rhizoma corydalis, notopterygium, root of herbaceous peony, prunella vulgaris, balloonflower and milettia reticulate. The production method operation is simple; the dose of the formed powder is accurate, the bioavailability is high and the effect-taking speed is quick. The medicine provided by the invention has obvious therapeutic effects for curing headache.

Description

A kind of Chinese powder medicine that is used for the treatment of headache

Technical field

The invention belongs to the Chinese medicine preparation technical field, relate to a kind of powder, be specifically related to a kind of Chinese powder medicine that is used for the treatment of headache, and its preparation method has been done correlational study.

Technical background

Headache means that diseases caused by exogenous pathogenic factor or internal injury cause chronic, the headache of incessant recurrence that stasis caused of a local passages through which vital energy circulates.Its wind syndrome of head or migraine are meant this type of headache, belong to the chronic headache of doctor trained in Western medicine.And TAI YANG headache does not belong to this type of headache.

In recent years, the agonist of American scholar invention 5-HT1D receptor was as Shu Mateliputan (5umntriptan).Although Chinese scholars has been done very big effort in this respect, create these therapies, can only be the respite migraine, its migrainous attack times is outbreak as usual still, so chronic headache remains one of problem of domestic and international research.I am in 27 years that have a headache with Chinese traditional treatment, and realizing the Chinese traditional treatment chronic headache is a big advantage of the traditional Chinese medical science, promptly can cure chronic headache with Chinese medicine, there is no the antipyretic-antalgic property of medicine chronic gastritis of obeying antipyretic analgesic and causing, the toxic and side effects of antipyretic-antalgic nephritis.But must be pointed out the headache of the traditional Chinese medical science, its etiology and pathogenesis complexity, typing is various, is difficult to grasp, and it is not good that therapeutic effect has.The etiology and pathogenesis of the headache that I grope to make new advances in the long-term treatment headache and new typing are executed the scheme of controlling, its curative effect has obviously improved major step, these are published in respectively in " Journal of Traditional Chinese Medicine ", " combination of Chinese and Western medicine magazine ", " a collection of selected materials of blood circulation promoting and blood stasis dispelling data ", " Beijing University of Chinese Medicine's journal ", " headache Differential Diagnosis and the treatment ", introduce the progress part of relevant headache in the authoritative works " practical Chinese Internal Medicine ", " clinical Chinese Internal Medicine " of the traditional Chinese medical science in recent years again.

Headache is one of tcm clinical practice common sympton, at tcm theory, think head for " confluence of all yang-channels ", " internal organs of clear sun ", the essence of five ZANG-organs and six FU-organs China annotates in head on all, so if QI and blood fills, the negative and positive lifting is as usual, no exopathogen is attacked, and then can not produce headache; No matter so be to experience wind, cold, wet, hot heresy, or expectorant is turbid, stagnation of blood stasis, causes through the gas superinverse; Or irritability stasis, strongly fragrant fire-transformation of a specified duration, on disturb key clearly; Or deficiency of vital energy clear YANG failing to ascend, blood deficiency can not the nutrition brain, all can cause headache, need remove the cause of disease when therefore treating, could alleviating pain, and the present invention provides correct traditional Chinese medical science prescription and rational drug according to the differentiation of tcm principle.

Summary of the invention

The object of the invention is to provide a kind of Chinese powder medicine that is used for the treatment of headache, comprises its material combination and preparation method.Medicine provided by the present invention has apparent in view therapeutic effect for headache.

Be achieved through the following technical solutions order of the present invention:

1, the present invention is the powder of being made by the Chinese medicine of following weight proportioning:

Radix Angelicae Sinensis 10-45 part Rhizoma Chuanxiong 15-30 part Ramulus Uncariae Cum Uncis 15-30 part

Radix Rehmanniae Preparata 10-45 part Rhizoma Corydalis 10-45 part Rhizoma Et Radix Notopterygii 10-45 part

Radix Paeoniae Alba 30-70 part Spica Prunellae 30-70 part Radix Platycodonis 50-80 part

Caulis Spatholobi 30-70 part

2, each raw material weight proportioning of the best of the present invention's prescription is:

20 parts of 20 parts of Ramulus Uncariae Cum Uncis of 35 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis

35 parts of 35 portions of Rhizoma Et Radix Notopterygiis of 35 parts of Rhizoma Corydalis of Radix Rehmanniae Preparata

70 parts of 50 parts of Radix Platycodoniss of 50 parts of Spica Prunellaes of the Radix Paeoniae Alba

50 parts of Caulis Spatholobis

3, preparation method:

(1) get the Radix Paeoniae Alba, be ground into fine powder, standby;

(2) get Radix Angelicae Sinensis, Ramulus Uncariae Cum Uncis, Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, mix, add 70% ethanol of 6～10 times of medical material amounts, flooded 6～10 hours, heating and refluxing extraction is three times then, and each 1 hour, merge extractive liquid, filtered, and decompression filtrate recycling ethanol is not hidden to there being alcohol, and is standby;

(3) get Radix Rehmanniae Preparata, Spica Prunellae, Radix Platycodonis, Caulis Spatholobi, mix, add the water of 6～10 times of medical material amounts, decoct 4 times, each 1～2 hour, filter, merging filtrate mixes with above-mentioned nothing alcohol flavor concentrated solution, and is concentrated into thick paste, and is standby;

(4) get thick paste, cold drying is ground into fine powder, adds Radix Paeoniae Alba fine powder and an amount of pharmacy adjuvant, and mix homogeneously is made powder, promptly.

The dosage of preparation is accurate after the simple to operate and molding of Chinese powder medicine production method of the present invention, the bioavailability height, and onset speed is fast.Medicine provided by the present invention has apparent in view therapeutic effect for headache.

The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.

The specific embodiment

Embodiment 1:

Adopt following material combination:

Radix Angelicae Sinensis 35g Rhizoma Chuanxiong 20g Ramulus Uncariae Cum Uncis 20g

Radix Rehmanniae Preparata 35g Rhizoma Corydalis 35g Rhizoma Et Radix Notopterygii 35g

Radix Paeoniae Alba 50g Spica Prunellae 50g Radix Platycodonis 70g

Caulis Spatholobi 50g

Its preparation method is:

(1) get Radix Paeoniae Alba 50g, be ground into fine powder, standby;

(2) get Radix Angelicae Sinensis 35g, Ramulus Uncariae Cum Uncis 20g, Rhizoma Corydalis 35g, Rhizoma Et Radix Notopterygii 35g, mix, add 70% ethanol of 8 times of medical material amounts, flooded 8 hours, heating and refluxing extraction is three times then, and each 1 hour, merge extractive liquid, filtered, and decompression filtrate recycling ethanol is to there not being the alcohol flavor, and is standby;

(3) get Radix Rehmanniae Preparata 35g, Spica Prunellae 50g, Radix Platycodonis 70g, Caulis Spatholobi 50g, mix, add the water of 8 times of medical material amounts, decoct 4 times, each 1 hour, filter, merging filtrate mixes with above-mentioned nothing alcohol flavor concentrated solution, and is concentrated into thick paste, and is standby;

(4) get thick paste, cold drying is ground into fine powder, adds Radix Paeoniae Alba fine powder and the about 97g of starch, and mix homogeneously sieves, and makes powder.

Embodiment 2:

Adopt following material combination:

Radix Angelicae Sinensis 45g Rhizoma Chuanxiong 30g Ramulus Uncariae Cum Uncis 30g

Radix Rehmanniae Preparata 45g Rhizoma Corydalis 45g Rhizoma Et Radix Notopterygii 45g

Radix Paeoniae Alba 70g Spica Prunellae 70g Radix Platycodonis 80g

Caulis Spatholobi 70g

Its preparation method is:

(1) get Radix Paeoniae Alba 70g, be ground into fine powder, standby;

(2) get Radix Angelicae Sinensis 45g, Ramulus Uncariae Cum Uncis 30g, Rhizoma Corydalis 45g, Rhizoma Et Radix Notopterygii 45g, mix, add 70% ethanol of 10 times of medical material amounts, flooded 9 hours, heating and refluxing extraction is three times then, and each 1 hour, merge extractive liquid, filtered, and decompression filtrate recycling ethanol is to there not being the alcohol flavor, and is standby;

(3) get Radix Rehmanniae Preparata 45g, Spica Prunellae 70g, Radix Platycodonis 80g, Caulis Spatholobi 70g, mix, add the water of 10 times of medical material amounts, decoct 4 times, each 1 o'clock, filter, merging filtrate mixes with above-mentioned nothing alcohol flavor concentrated solution, and is concentrated into thick paste, and is standby;

(4) get thick paste, cold drying is ground into fine powder, and the ratio that adds Radix Paeoniae Alba fine powder and starch and lactose is 4: 1 the about 168g of mixture, and mix homogeneously makes powder.

Claims (3)

1, a kind of Chinese powder medicine that is used for the treatment of headache is characterized in that it comprises that unit of weight is a raw material by the following Chinese medicine of part:

Radix Angelicae Sinensis 10-45 part Rhizoma Chuanxiong 15-30 part Ramulus Uncariae Cum Uncis 15-30 part

Radix Rehmanniae Preparata 10-45 part Rhizoma Corydalis 10-45 part Rhizoma Et Radix Notopterygii 10-45 part

Radix Paeoniae Alba 30-70 part Spica Prunellae 30-70 part Radix Platycodonis 50-80 part

Caulis Spatholobi 30-70 part.

2, a kind of Chinese powder medicine that is used for the treatment of headache as claimed in claim 1 is characterized in that the weight proportion of each raw material is:

20 parts of 20 parts of Ramulus Uncariae Cum Uncis of 35 parts of Rhizoma Chuanxiongs of Radix Angelicae Sinensis

35 parts of 35 portions of Rhizoma Et Radix Notopterygiis of 35 parts of Rhizoma Corydalis of Radix Rehmanniae Preparata

70 parts of 50 parts of Radix Platycodoniss of 50 parts of Spica Prunellaes of the Radix Paeoniae Alba

50 parts of Caulis Spatholobis.

3, as the described a kind of Chinese powder medicine that is used for the treatment of headache of claim 1-2, it is characterized in that the preparation method of this powder is:

(1) get the Radix Paeoniae Alba, be ground into fine powder, standby;

(2) get Radix Angelicae Sinensis, Ramulus Uncariae Cum Uncis, Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, mix, add 70% ethanol of 6～10 times of medical material amounts, flooded 6～10 hours, heating and refluxing extraction is three times then, and each 1 hour, merge extractive liquid, filtered, and decompression filtrate recycling ethanol is to there not being the alcohol flavor, and is standby;

(3) get Radix Rehmanniae Preparata, Spica Prunellae, Radix Platycodonis, Caulis Spatholobi, mix, add the water of 6～10 times of medical material amounts, decoct 4 times, each 1～2 hour, filter, merging filtrate mixes with above-mentioned nothing alcohol flavor concentrated solution, and is concentrated into thick paste, and is standby;

(4) get thick paste, cold drying is ground into fine powder, adds Radix Paeoniae Alba fine powder and an amount of pharmacy adjuvant, and mix homogeneously is made powder, promptly.