CN101238982A - Device and method for determining the muscular activity of a physiological body - Google Patents
Device and method for determining the muscular activity of a physiological body Download PDFInfo
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Abstract
An apparatus (100) for determining muscular activity of a physiological body, said apparatus (100) comprising a pneumatic mechanism (101 to 105) for pneumatically determining muscular activity of a physiological body.
Description
Technical field
The present invention relates to a kind of device of measuring physiological organism muscular work.
The invention still further relates to a kind of method of measuring physiological organism muscular work.
And, the present invention relates to a kind of program element.
In addition, the present invention relates to a kind of computer-readable medium.
In addition, the invention still further relates to the method for using a kind of device, it is of flaccid muscles that described device is measured the caused physiological organism of medicine.
Background technology
Myography can refer to describe the science of muscle, comprises the research of muscle contraction.
Muscular tremor is traced (MMG) at Viby-Mogensen J, Engbaek J, people such as Eriksson LI are in Acta Anaesthesiol Scand 1996,40:59-74 deliver " disclosed in " Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents (about the good clinical trial of the pharmacodynamic studies of neuromuscular blocking drug) " literary composition, muscular tremor is traced based on the measurement that irriate muscle is produced strength.
Electromyogram (EMG) equipment is known (for example M-NMT module of Finland Datex Ohmeda company), and it is based on the measurement that irriate muscle is produced voltage.
Acceleration tracing (AMG) is at Loan PB; Paxton LD; Mirakhur RK; Deng the people in Anaesthesia 1995, " The TOF-Guard neuromuscular transmissionmonitor.A comparison with the Myograph 2000 (the neuromuscular transmission monitor of TOF protection that 50:699-702 delivers.Comparison with myograph 2000) " disclosed in the literary composition, the acceleration tracing is based on the measurement to the acceleration of patient's thumb.
In addition, the method that is wrapped with crooked press belt between two fingers of patient also can be used, the signal of telecommunication of its generation can indicate flexibility (to see Dahaba AA, Klobucar F, Rehak PH, List WF is at BrJAnaesthesia, 1999, " Comparison of a new piezoelectrictrain-of-four neuromuscular monitor; the ParaGraph, the and the Relaxometermechanomyograph (comparison that a kind of new-type four one rows' piezoelectric type neuromuscular watch-dog and Relaxometer muscular tremor are traced) " that delivers on the 82:780-2)
Yet the moving scanning device of known flesh is too complicated when making and use, and/or lack flexibility ratio in operation.
Summary of the invention
One of purpose of the present invention is to make the moving scanning device of flesh effective.
In order to realize the foregoing invention purpose, this paper provides a kind of device of definite physiological organism muscular work according to independent claims, a kind of method of definite physiological organism muscular work, a kind of program element, a kind of computer-readable medium, with the method for using a kind of device, it is of flaccid muscles that described device is measured the caused physiological organism of medicine.
According to an embodiment exemplary of the present invention, a kind of device of measuring physiological organism muscular work is provided, this device comprises a pneumatic mechanism of determining (perhaps monitoring) physiological organism muscular work with air effect.
According to another embodiment exemplary of the present invention, a kind of method of definite physiological organism muscular work is provided, this method comprises with air effect determines (perhaps monitoring) physiological organism muscular work.
According to another embodiment exemplary of the present invention, a kind of computer-readable medium is provided, stored a computer program that is used for determining physiological organism muscular work in this medium, when processor was carried out this program, it can control or realize having the method for above-mentioned characteristic.
According to another embodiment exemplary of the present invention, a kind of program element that is used for determining physiological organism muscular work is provided, when processor was carried out this program, it can control or realize having the method for above-mentioned characteristic.
According to another embodiment exemplary of the present invention, used a kind of device with above-mentioned characteristic, described device is used to determine that the caused physiological organism of medicine is of flaccid muscles.
According to embodiments of the invention, device control, the signal that can be performed produce and signal processing, these can be realized by the form of computer program with software, perhaps realize, perhaps realize by the mixed form of component software and nextport hardware component NextPort by one or more optimization circuit special in the hardware.
In the application's text, term " pneumatic mechanism " can refer in particular to one and make its operationalization by hydraulic pressure or as the Compressed Gas of air but operate, and by the system of its driving or filling.Term " pneumatic mechanism " may be relevant to or use a media just as fluid, liquid, gas (pressurization), gelinite, semi-solid (as hydrargyrum); Or solid (for example powder or granular substance).
Term " physiological organism " may refer in particular to a people (child or adult, woman or man), perhaps an animal (for example monkey).
Term " air bag " (perhaps big envelope) may refer in particular to a kind of physical arrangement, and it can be for example selected from following tabulation:
Reusable form or;
2. the form of a unique purposes (disposable);
3. simply use the big envelope of an easy-to-use endotracheal tube.
According to an embodiment exemplary, provide a flesh to move scanning device, wherein can be fixed on aerating gasbag on people or the animal palm.For example, by the electricity irritation of specific muscles on hand, when physiological organism (referring to that people or animal here) when demonstrating musculation, stimulation will cause physiological organism muscle contraction on hand, thereby adjusts or revise the pressure in the air bag.This stress reaction can be measured and be can be used as the foundation that whether takes place of flaccid muscles of judging physiological organism.For instance, as be used for anesthesia when treatment of surgical operation or its analog and under the effect of the medicine implemented, characteristics of flaccid muscles can be according to the measurement of patient (remaining) musculation and monitored or adjust.So a simple muscular irritation can be implemented in a kind of very simple mode according to embodiments of the invention in conjunction with the pneumatic gauging to musculation or degree of flaccid muscles.Therefore, according to an embodiment exemplary, the moving scanning device (CMG) of pneumatic flesh can be provided.
In the anesthesia field, by reducing or eliminating muscular tone, of flaccid muscles can being employed so that the surgeon is easier of drug-induced implemented surgical operation to the patient.On the other hand, this situation also occurs in when needing to make the patient to be in a kind of special position in the operation.Embodiments of the invention make to accurate monitoring of flaccid muscles and simultaneously under the situation of not disturbing musculation to measure and the arrangement patient of high flexible becomes possibility.
For this purpose, of flaccid muscles in order to monitor, a special nerve (for example ulna nerve) can be installed in one or more (generally being two) the electrode electricity irritation near wrist.For example, lasting 200ms and frequency be 2 hertz rectangular signal can be used 2 seconds (" four one rows ", TOF).When the patient is in the state that muscle do not loosen (just, remaining musculation in addition), this processing causes a stimulation of adductor pollicis, thereby causes the interior receipts of thumb.When increasing lax (just, losing musculation), this action can be suppressed gradually, and complete obiteration under a unexpected state.
Trace in (MMG) at traditional muscular tremor, can be measured by the strength that the muscle of irriate produces.For the direct measurement of clinical relevant parameter (strength), the ability of this system is can be gratifying.But, when using this device, trace measurement for muscular tremor, patient's accurate position is necessary, therefore, do not have postural change may and also the research of the special applications that only is applicable to of MMG.
According to traditional electromyogram (EMG), it is measured that muscular irritation produces voltage.Voltage can obtain relaxation information, but the degree of accuracy deficiency.
In traditional acceleration method (AMG), the acceleration that is subjected to the thumb of muscular irritation can be measured.But in some special application, acceleration method can not provide enough degree of accuracy equally.
The traditional measurement that the bending of tying up the press belt on forefinger and thumb is carried out can obtain the signal of telecommunication that the degree according to bending produces.Although this method has certain flexibility ratio on patient's position, its accuracy deficiency.
According to an embodiment exemplary, air bag can be filled (for example gas and/or liquid) by media, for example can be by 20 milliliters fills with air, and then be placed on patient's the palm.Optionally, a sheet can be placed in or be positioned on the forefinger and/or thumb of open hands.Such power transmit element can be efficiently with the pressure of thumb or strength transmission to air bag, therefore increase the accuracy of measurement.Then, patient's hands can have been held or fix with elastic bandage.Air bag connects a pressure transducer.There is not the pressure of lax air bag can be calibrated to a reference value (for example " 100 ").Then, use ulna nerve of traditional nerve stimulation deposits yields to stimulate.Along with muscle lax (for example be used in the medicine that control is used in the anesthesia process and reach lax) gradually, thumb can reduce the pressure of air bag, and therefore the pressure in air bag also reduces.The measurement result data can be interpreted as the relax level of muscle.
So, according to an embodiment exemplary, clinical interested target component, the pressure or the strength of patient's (for example life entity of anesthesia treatment) generation just can directly be measured.On the other hand, because the design of sensor-based system, the high flexibility ratio relevant with position opportunity in the operation is retained.An embodiment like this can be used as a module in the anesthesia watch-dog or (independent) standalone module monitoring as neuromuscular.
According to an embodiment exemplary, according to the pressure that acts on air bag in patient's hands that patient's muscle strength produces, (for example under narcotic effect) of flaccid muscles can be measured, and wherein musculation is triggered by (for example electric current) muscular irritation.
So a neuromuscular transmission monitor can be provided, it is represented as the moving scanning device (CMG) of compression flesh, is used for nervimuscular monitoring.
Then, more embodiment will be explained.But these embodiment also are applicable to a kind of method of definite physiological organism muscular work, a computer-readable medium, and a kind of program element and a kind of method of using this device, described device is used for determining the musculation of the drug-induced of physiological organism.
Pneumatic mechanism comprises the air bag that can be filled by media.Term " pneumatic " refers in particular to the pressure of compressible fluid, described pressure be can be measured the power that on air bag or similar object, applies by the patient.Such air bag can have one to be globular shape basically.Other geometry also can, flat elliptical shape for example, a cubold or other analogous shapes.Shape can be adjusted according to the dissection of people or animal patient.Such air bag is made by elastomeric material, and its pliability allows the patient when it is exerted pressure on air bag, shape that can sizable change air bag.Air bag is inflatable, that is to say can throw fluid into air bag or from air bag fluid is discharged.
Air bag can be adjusted so that be placed in the hands of physiological organism.So, shape, material, and the stress reaction characteristic can be adjusted to the value that is suitable for specific physiological organism use.
Pneumatic mechanism comprises that one and air bag carry out the media pipe (as a plastic cement pipe) of fluid communication.This media pipe is one can be hollow pipe, for example makes with plastic material, and filler cells that is suitable for filling air bag and air bag are linked together.This filler cells is an accumulator, such as the gas cylinder in the laboratory, pump or pressure air linker, or the like.So, by media pipe (can be that inflexible material is made and had little internal diameter to reduce " dead volume " basically) air bag and filler cells are coupled together, air bag can optionally be in a kind of extension/expansible state or relaxed state.A valve gear or analog can be provided between filler cells and air bag, and this valve gear opens or closes the acquiescence pressure that can adjust air bag like this.
Outside this, this device should comprise a fixed part, air bag can be fixed in the hands of physiological organism by adjusting it.By air bag being fixed in patient's hands, the reliability of system will be promoted significantly, and this is can be guaranteed because of the suitable strength that passes to air bag from hands.The example of a this fixed part can be an elasticity band or binder, it around be entangled in hold air bag the patient on hand, it also can have a fixed mechanism, such as a snap-fastener, a buckle, perhaps a VELCRO.
This device should comprise that one is used for exciting nerve, particularly the stimulating unit of physiological organism ulna nerve.Ulna nerve refers to the person and goes up the nerve that extends downwardly into hands from big arm and forearm.
This stimulating unit should comprise being connected to also gives the electrode of physiological organism with galvanism on the physiological organism.For example, two electrodes can be placed on the special area of patient skin, and the stimulating current signal is applied in to the patient, cause the action of thumb muscles.This stimulating unit can be by user program so that define as time sequencing the stimulation programs of the electric wave width of cloth etc.
A pressure transducer is provided the pressure that is used for measuring (perhaps in the media pipe) in the air bag, particularly when measuring by to the inflation of small part the time.Pressure sensor/gauge can be pressure transducer (MEMS for example, Pressure gauge, an air velocity indicator arbitrarily, pick off based on piezoelectricity, based on diaphragm-operated strength sensor, based on the pick off of elastic force, perhaps effusion meter) and be connected on media pipe and the air bag.Pressure when muscle response is moved to the physiological organism nerve stimulation in the air bag can change, and pressure transducer can detect the pressure of different time points in the air bag.So muscle movement or of flaccid muscles can by pressure transducer detected.The pipe that connects air bag and pressure transducer is incompressible in essence, can avoid because of described pipe compression like this or the patient's muscle movement due to expanding, and the pressure of the air bag that causes thus changes.So the accuracy of native system has obtained improving significantly.
A kind of strength transmission part also can be provided, and it is used to promote that the hands from the physiology body transmits strength to air bag.This strength transmission part can be arbitrary physical unit or member that improves the strength association between air bag and hands.For example, can provide first rigid element (as plastic strip) that is provided with along the finger of physiological organism palm row (the preceding finger that comprises hands, the i.e. finger of all the other except thumb).Thumb along the physiological organism palm can be provided with second rigid element, and it also can be plastic strip.Described two plastic strips cooperate on function and as unitary two limits of lever.Therefore, when patient's musculation is intact, even slight muscle strength also can be converted into sizable pressure in the air bag.
Pneumatic mechanism is of flaccid muscles applicable to pneumatic monitoring of physiologic body.This fractional reduction or the complete obiteration that can be musculation of flaccid muscles is as muscle relaxant or suck as of flaccid muscles at due to patient's the anesthetis.
Described device can comprise that one makes the user control this device, operates this device, and/or the user interface of the musculation of supervisory physiological organism.Described user interface can comprise a display unit (as LCD display, cathode ray tube, plasma display or its analog) and can therefore comprise a graphic user interface (GUI).User interface can further comprise input block, described input block such as button, keyboard, control stick, trace ball or even be little phone of sound recognition system.This user interface can be computer or the handheld device that assisted user makes things convenient for operative installations.This user interface can with the control unit communication, the component that is used for controlling this device in the center is to improve the automaticity of system.
According to an embodiment that can imitate of the present invention, described system can be used to measure the of flaccid muscles of drug-induced physiological organism, particularly is determined as the drug dose that applies in the predeterminated level value and at physiological organism of flaccid muscles that keeps physiological organism.Therefore, in surgical procedures, the Anesthetist can continuity ground or monitor the state of flaccid muscles of surgical operation target patient every now and then.
Description of drawings
The further each side of above-mentioned aspect and the present invention will be understood at the embodiment in the following embodiment and be set forth as example with reference to those.
Fig. 1 is for measuring physiological organism device of flaccid muscles according to one exemplary embodiment of the present invention;
Fig. 2 to Figure 11 is each parts of mensuration physiological organism device of flaccid muscles, and the method for using this device according to one exemplary embodiment of the present invention;
Figure 12 is the Bland and the Altman scatterplot of moving scanning device (CMG) of compression flesh and the moving scanning device of muscular tremor flesh;
Figure 13 is the regression curve of the moving scanning device (CMG) of compression flesh with respect to the moving scanning device of muscular tremor flesh;
Figure 14 is the Bland and the Altman scatterplot of moving scanning device (CMG) of compression flesh and the moving scanning device of muscular tremor flesh;
Figure 15 is the regression curve of the moving scanning device (CMG) of compression flesh with respect to the moving scanning device of muscular tremor flesh;
Figure 16 be six patients use the Luo Ku ammonium and cause of flaccid muscles during, by the moving scanning device (CMG) of compression flesh and the T1% of moving scanning device (MMG) mensuration of muscular tremor flesh and the average of TOF;
After Figure 17 is patient's excitement formerly, apply with after the muscle relaxant order of the reaction signal of patient's hands then;
Figure 18 has shown the geometry of plate like rigid element, and described rigid element is used for measuring according to one exemplary embodiment of the present invention the device of physiological organism muscular work.
The specific embodiment
This description of drawings is schematic.In different figure, similar or same parts are marked by identical drawing reference numeral.
A kind of device 100 of measuring patient's musculation according to one exemplary embodiment of the present invention with reference to Fig. 1, will be described in following ground.
Pneumatic mechanism comprises a compressibility plastic gas bag 101, and this air bag has for example volume of 20ml under full state, so the adult that this size can be used as physiological organism is placed in the hands.This air bag 101 is obtained by elastoplast, and can be inflated by air.
Can predict a pipeline 102 as the hollow pipe element, it is incompressible and is communicated with to carry out fluid communication by a three-way valve 120 with inflatable airbag 101.Described three-way valve 120 can be communicated with on 101 to pressure transducers 103 of described air bag by selectivity, or is connected with gas container 105 or pump by a further optional valve 104.
When the described air bag 101 of three-way valve 120 connections was to gas container 105 or pump, air bag 101 can be thrown into gas to be filled.When three-way valve 120 was communicated with described air bag 101 to pressure transducer 103, the pressure in the air bag 101 can be measured (disposable, every now and then or seriality ground).
In addition, provide a binder 106 with when accepting or locate this air bag to human patient's the hands the time, and fixed this air bag.This binder 106 is weaved cotton cloth 107 obtained by the elasticity with long rectangular shape, and has VELCRO parts 108, with when it twines around patient's hands of holding air bag 101, and can immovable bandage 106.
Further show as Fig. 1 institute, provide one to be used to excite nerve, especially stimulate the muscular irritation unit 109 of patient's ulna nerve.This stimulating unit 109 comprises the control unit 110 of 109 operations of a control stimulating unit, electromotive force application etc., and comprises two electrodes 111 that are connected with described control unit 110 by cable 112.When activating described stimulating unit 109, and when described electrode 111 is set on the human patients skin appropriate location, described stimulating unit just can stimulate ulna nerve, and when the muscle of human patients was in inactive state, ulna nerve can cause the action of staff.
Described pressure transducer 103 be set to when air bag by when small part is full of and measure pressure in the air bag 101.This pressure can change air bag in response to the nerve stimulation of human patients, and this is because this stimulation can cause the muscle movement of hands.
Fig. 1 shown in further a plate like rigid element 113, its shape and size are applicable to the thumb that is arranged on the human patients hands.Further, provide a plate like rigid element 114 as the second strength transmission part, its shape is applicable to be arranged on and is applicable to that the finger that is arranged on the human patients hands lists.
In addition, but provide a center to control the control unit (for example, computer, CPU, microprocessor or its analog) 115 of described device 100 operations.Described control unit 115 can carry out both-way communication with I/O unit 116, pressure transducer 103, valve 104, inflation unit 105 and muscular irritation unit 109 especially.Therefore, described control unit 115 can provide control instruction each these parts or miscellaneous part to described device 100, also can receive information from these parts.
I/O unit 116 can be a user interface, and it makes the user can control the operation of described device 100, monitors the musculation of human patients.Each communication pipeline 117 can be wired or wireless.When line structure is arranged, pipeline 117 can comprise cable, and when wireless topology, be bluetooth, infrared or other enforceable wireless telecommunications schemes.
According to a further exemplary embodiment of the present invention, but air bag 101 and two sheet 113,114 integral types formation also promptly form as parts.Alternatively, binder 106 also can be connected on air bag 101 and/or two sheets 113,114 and form structure to form an integral type.This mode has improved the convenience that the user operates described device 100.Also can omit sheet 113,114.Under this scene, can may substitute sheet 113,114 by the air bag part that correspondingly fixedly positioning, the described air bag part that fixedly positioning can improve or improve the strength transmission.Therefore, described strength transmission part 113,114 and described air bag 101 integral types form and are fine.
Following ground with reference to Fig. 2 to Figure 11, is measured the operation of the described device 100 of physiological organism muscular work and will be set forth according to one exemplary embodiment of the present invention.
In Fig. 2 to Figure 11, inflatable airbag 101 is realized by an endotracheal tube (feasible ground, as, the product of the Hi-Contour by name of Mallinckrodt company).According to one exemplary embodiment of the present invention, in this endotracheal tube, only used inflatable airbag 101 and its corresponding pipeline 102, wherein other duct members can keep unused state.Specifically, shown a duct member 1102 that in the embodiment that describes, is not used.Inflatable airbag 101 inside are connected to be used for fluid communication with described pipeline 102 by opening 200.An end points 201 of described pipeline 102 seals.
Fig. 2 has shown inflatable airbag 101 and duct member 1102.The size of described air bag 101, shape can be predicted it and can be filled into or throw into the air of 20ml.
Fig. 3 has shown patient's hand 300, and it comprises that a palm 301, thumb 302 and one refer to row 303.Under the mode of operation of Fig. 3, inflatable airbag 101 is located on patient's the palm.
As shown in Figure 4, sheet 113,114 is positioned and moves to the ability of air bag 101 to improve accurate transmission thumb 302.This thumb action is indicated by reference number 400.Sheet 113 is positioned to extend along the palm 301 of thumb 302 to hands 300.Sheet 114 is along referring to that row 303 are positioned, and its direction is perpendicular with the extension of finger 303 basically.
As shown in Figure 5, binder 106 guaranteeing the location of air bag 101 and/or sheet 113,114, and produces opposite pressure to inflatable air bag 101 strength around hands 300 location simultaneously.
Fig. 6 has shown the binder 106 under the mode of operation, and its hands 300 around the people twines and be fastened.
Therefore, described system is well fixed, and patient's hands 300 can move freely.
Fig. 7 is when binder 106 is wrapped on the hands 300, a further view of patient's hands.
Fig. 8 has shown nerve stimulation unit 110, and it is used for by the ulna nerve of electrode transmission pulse to human patient.
Referring now to Fig. 9, the electrode 111 of stimulating unit 110 stimulates ulna nerve by surface electrode on the skin or subaermal needle electrod, and described subaermal needle electrod is provided with by people's skin of arm.
As shown in Figure 9, when ulna nerve was stimulated, thumb 302 was with regard to interior receipts.
At mode of operation, people's N﹠M be active (as, in orthobiosis or for before preparing operating anesthetis effect), the interior receipts 400 of thumb 302 will compression bladders 101 and will be made the pressure change that pressure transducer 103 is measured in the air bags 101.These information can be transferred to control unit 115 by connecting 117, and control unit 115 can output an information display unit of giving I/O element 116 correspondingly.
Yet, when of flaccid muscles when appearing in patient's body (as, self-supporting patient uses the medicine that is used to anaesthetize), as shown in figure 10, receive 400 (or only being interior receipts reduction or time-delay) in not having and take place.Therefore, in air bag 101, be measured as no pressure and change, and the surgeon to confirm that this patient does not have remaining of flaccid muscles.
As shown in Figure 11, the change of air bag 101 internal pressures reduces to pressure transducer 103 (not shown) by incompressible formula pipeline 102.As shown in Figure 1, can predict a three-dimensional formula valve 120 so that fluid (or how general media) exchange.
Figure 16 be six patients use the Luo Ku ammonium and cause of flaccid muscles during, by the moving scanning device (CMG) of compression flesh and the T1% of moving scanning device (MMG) mensuration of muscular tremor flesh and the average of TOF.
Figure 17 be the patient in excitement after 4 times, the order of its hand reaction signal is respectively and the patient is being imposed loosening all muscles agent (at anestheticing period) before and afterwards.
More properly, Figure 17 has shown Figure 170 0, and the abscissa 1701 that it has identified time also has in pneumatic system of being identified at (as shown in Figure 1) vertical coordinate 1702 by the density of the measured muscle contraction of pressure transducer.
First order of four equidistant signals 1703, by be provided with device shown in Figure 1 the patient on hand after, and use a muscular irritation pulse and measure to the patient.Subsequently, use with a loosening all muscles thing for this patient at the time point shown in the reference number 1704.After this, second order of four equidistant signals 1705, by be provided with device shown in Figure 1 the patient on hand after, and make the patient be in active state, under this state, use a muscular irritation pulse and measure to the patient.As the result who imposes the loosening all muscles thing, it is more and more slower that musculation becomes.
Can indicate opiate whether to suppress the activatory significant parameter of patient's musculation, be T1: the ratio value of T0 and T4: T1.Yet,, also can implement other activation scheme or evaluations of programme according to exemplary embodiment of the present invention.
Figure 18 is that it can be used like lamellar rigid element 113 and 114 employed same way as by above-mentioned optionally like the geometry of lamellar rigid element 1800 and 1810.
Like the shape and size of lamellar rigid element 1800, on function, make it can be suitably locate along the thumb (schematically being marked) of human patients palm by reference number 1801.The primary seal of hands is closed part and is schematically marked by reference number 1802.Be designed to mate the dissection of staff like lamellar rigid element 1800, and make that the patient can no pain or the inconvenient sheet 1800 that carries with feeling.For this purpose, comprise a thickening part 1803 with mechanical consolidation effect like lamellar rigid element 1800.In addition, comprise that like lamellar rigid element 1800 a thin extension 1804 is to prolong along patient's palm easily.For convenience, the angle 1805 like lamellar rigid element 1800 is circular.Be essentially orthogonal like lamellar rigid element 1800 so applicable to the dissection of mating staff.
Like the shape and size of lamellar rigid element 1810, on function, make it to be listed as along the finger of human patients palm and to locate.Be designed to mate the dissection of staff like lamellar rigid element 1810, and make that the patient can no pain or the inconvenient sheet 1810 that carries with feeling.For this purpose, comprise a thickening part 1803 with mechanical consolidation effect like lamellar rigid element 1810.In addition, have straight geometry and comprise that one is essentially orthogonal like lamellar rigid element 1800, wherein for convenience, seemingly the angle 1811 of lamellar rigid element 1810 is circular.The design plane part is to be applicable to the dissection of coupling staff.
Subsequently, provide a strength transmission part that comprises element 1800,1810, described element 1800,1810 is designed the dissection in order to the coupling staff.
What need to indicate is, term " comprises " and do not refer to get rid of other elements or step, and " one ", " a kind of " do not refer to get rid of a plurality of.Can the element that be associated with different embodiment is combined.
What need indicate equally is that the reference number in the strong request should not be interpreted as the restriction to the strong request scope.
Claims (31)
1, a kind of device (100) that is used to measure physiological organism muscular work, it comprises a pneumatic mechanism (101 to 105), described pneumatic mechanism is used for pneumatically measuring physiological organism muscular work.
2, device according to claim 1 (100) is characterized in that described pneumatic mechanism (101 to 105) comprises an air bag (101), and described air bag (101) is filled by fluid especially by media.
3, device according to claim 2 (100), the shape and size that it is characterized in that described air bag (101) are applicable in the staff holds it.
4,, it is characterized in that described pneumatic mechanism (101 to 105) comprises the pipeline (102) that is connected with air bag (101) phase fluid according to claim 2 or 3 described devices (100).
5,, it is characterized in that described pneumatic mechanism (101 to 105) comprises the filler cells (104,105) of selectivity filling air bag (101) according to the described device of the arbitrary claim of claim 2-4 (100).
6, device according to claim 5 (100), it is characterized in that described filler cells (104,105) is connected with described air bag (101) by fluid line (102) in order to carry out fluid communication between described filler cells (104,105) and described air bag (101).
7,, it is characterized in that described device (100) comprises that one is used for fastening described air bag (101) to the interior secure component (106) of physiological organism hands (300) according to the described device of the arbitrary claim of claim 2-6 (100).
8, device according to claim 7 (100) is characterized in that described secure component (106) comprises an elastic bandage.
9,, it is characterized in that described device (100) comprises a stimulating unit (109) that is used to stimulate the physiological organism nerve according to the described device of the arbitrary claim of claim 1-8 (100).
10, device according to claim 9 (100) is characterized in that described stimulating unit (109) is used to stimulate the ulna nerve of physiological organism.
11, according to claim 9 or 10 described devices (100), it is characterized in that described stimulating unit (109) comprises one or more electrodes that link to each other with physiological organism (111), to be used for from described stimulating unit (109) to electrical stimulation signal of physiological organism transmission.
12,, it is characterized in that described device (100) comprises a pressure transducer (103) that is used to measure intracapsular pressure according to the described device of the arbitrary claim of claim 2-11 (100).
13, device according to claim 12 (100) is characterized in that described pressure transducer (103) is used to measure the pressure that produces in response to the nerve stimulation of physiological organism in the air bag (101) and changes.
14,, it is characterized in that described device (100) comprises one in order to be communicated with incompressible basically pipeline (102) of described air bag (101) and described pressure transducer (103) according to claim 12 or 13 described devices (100).
15, according to the described device of the arbitrary claim of claim 2-14 (100), it is characterized in that described device (100) comprises a strength transmission part (113,114), be used to promote the transmission of strength between hands (300) at physiological organism and described air bag (101).
16, device according to claim 15 (100) is characterized in that described strength transmission part comprises one along the finger of physiological organism row (303) and localized first rigid element (114).
17,, it is characterized in that described strength transmission part comprises a thumb along physiological organism (302) and localized second rigid element (113) according to claim 15 or 16 described devices (100).
18, according to claim 16 or 17 described devices (100), it is characterized in that at least one parts in described first rigid element (114) and described second rigid element (113) comprise at least a structure in the following structure, these structures are band, sheet and bar.
19,, it is characterized in that described pneumatic mechanism (101 to 105) is used for the of flaccid muscles of monitoring of physiologic body pneumatically according to the described device of the arbitrary claim of claim 1-18 (100).
20, according to the described device of the arbitrary claim of claim 1-19 (100), it is characterized in that described device (100) comprises a user interface elements (116), to be used for the allowing user carry out at least a of following operation, these operations comprise control described device (100), the musculation of operating described device (100) and monitoring physiological body.
21,, it is characterized in that described strength transmission part (113,114) and described air bag (100) integral type form according to the described device of the arbitrary claim of claim 15-20 (100).
22,, it is characterized in that described strength transmission part comprises the parts (1800,1810) that one or more dissections that are designed for staff are complementary according to the described device of the arbitrary claim of claim 1-21 (100).
23, a kind of method that is used to measure physiological organism muscular work, this method comprises the musculation of pneumatically measuring physiological organism.
24, method according to claim 23 is characterized in that described method comprises to fix an inflatable airbag (101) to the palm (301) of the hands (300) of physiological organism.
25, method according to claim 24 is characterized in that described method comprises described air bag (101) is filled.
26, according to the described method of the arbitrary claim of claim 23-25, it is characterized in that the nerve that described method comprises stimulates physiological organism.
27, method according to claim 25 is characterized in that described method comprises that measuring the pressure that produces in response to the physiological organism nerve stimulation in the air bag changes.
28, a kind of computer readable medium, wherein stored a kind of computer program of measuring physiological organism muscular work, when processor (115) was carried out this computer program, described program was used to carry out the described method of arbitrary claim among the claim 23-27 is controlled.
29, a kind of program element that is used to measure physiological organism muscular work, when processor (115) was carried out this program element, described program element was used to carry out the described method of arbitrary claim among the claim 23-27 is controlled.
30, the method for the described device of arbitrary claim (100) among a kind of use claim 1-22 is used to measure physiological organism of flaccid muscles of drug-induced.
31, method according to claim 30 is characterized in that described method comprises the device (100) that is used to control drug dose, and described medicine imposes physiological organism to keep described physiological organism of flaccid muscles.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100093458A CN101238982A (en) | 2008-02-25 | 2008-02-25 | Device and method for determining the muscular activity of a physiological body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100093458A CN101238982A (en) | 2008-02-25 | 2008-02-25 | Device and method for determining the muscular activity of a physiological body |
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| CN101238982A true CN101238982A (en) | 2008-08-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2008100093458A Pending CN101238982A (en) | 2008-02-25 | 2008-02-25 | Device and method for determining the muscular activity of a physiological body |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102697506A (en) * | 2012-05-29 | 2012-10-03 | 广州乾华生物科技有限公司 | Method and system for monitoring action response condition |
| CN103124518A (en) * | 2010-07-07 | 2013-05-29 | Tmg-Bmc公司 | Method and device for non-invasive and selective determination of biomechanical, contractile and viscoelastic properties of surface skeletal muscles |
| CN103167828A (en) * | 2010-10-20 | 2013-06-19 | 皇家飞利浦电子股份有限公司 | Method and apparatus for diagnosing obstructive sleep apnea with an awake patient |
| CN107137098A (en) * | 2017-04-27 | 2017-09-08 | 山西师范大学 | A kind of fixed device for measuring force of rabbit jump |
| CN113974614A (en) * | 2015-02-04 | 2022-01-28 | 艾瑞迪尔通信有限公司 | Determining health changes of a user using neuro and neuro-mechanical fingerprints |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103124518A (en) * | 2010-07-07 | 2013-05-29 | Tmg-Bmc公司 | Method and device for non-invasive and selective determination of biomechanical, contractile and viscoelastic properties of surface skeletal muscles |
| CN103124518B (en) * | 2010-07-07 | 2015-11-25 | Tmg-Bmc公司 | For non-invasively and optionally measure the method and apparatus of the biomechanics of surface skeletal, contraction and viscoelastic property |
| CN103167828A (en) * | 2010-10-20 | 2013-06-19 | 皇家飞利浦电子股份有限公司 | Method and apparatus for diagnosing obstructive sleep apnea with an awake patient |
| CN103167828B (en) * | 2010-10-20 | 2016-02-24 | 皇家飞利浦电子股份有限公司 | For diagnosing the method and apparatus of the obstructive sleep apnea of clear-headed patient |
| US10165959B2 (en) | 2010-10-20 | 2019-01-01 | Koninklijke Philips N.V. | Method and apparatus for diagnosing obstructive sleep apnea with an awake patient |
| CN102697506A (en) * | 2012-05-29 | 2012-10-03 | 广州乾华生物科技有限公司 | Method and system for monitoring action response condition |
| CN113974614A (en) * | 2015-02-04 | 2022-01-28 | 艾瑞迪尔通信有限公司 | Determining health changes of a user using neuro and neuro-mechanical fingerprints |
| CN107137098A (en) * | 2017-04-27 | 2017-09-08 | 山西师范大学 | A kind of fixed device for measuring force of rabbit jump |
| CN107137098B (en) * | 2017-04-27 | 2020-02-21 | 山西师范大学 | Force measuring device for rabbit jumping and fixing |
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