CN101234162A

CN101234162A - Chinese medicine formula for treating leukoderma and preparation thereof

Info

Publication number: CN101234162A
Application number: CNA2007101448871A
Authority: CN
Inventors: 汤铁强
Original assignee: Individual
Current assignee: Individual
Priority date: 2007-12-21
Filing date: 2007-12-21
Publication date: 2008-08-06

Abstract

The invention relates to a Chinese traditional medicine preparation, which particularly relates to an internal treatment formula Zijin powder and an external treatment formula Lithargyrum ointment for match usage of vitiligo treatment. The internal treatment formula Zijin powder can effectively regulate the human immune system and endocrine dyscrasia and plays a role of promoting qi and activating blood circulation, nourishing liver and kidney, warming yang and reinforcing spleen, while the external treatment formula Lithargyrum ointment can effectively repair melanocyte of human skin and promote the generation of melanin. The Chinese traditional medicine preparation of the invention has an effective rate of 100 percent for the adolescent patients, and has an effective rate of more than 90 percent in three to six months for the patients with mild symptoms. The Chinese traditional medicine preparation of the invention is of easy oral administration, remarkable curative effect and is suitable for various kinds of vitiligo patients.

Description

A kind of treatment by Chinese herbs vitiligo prescription and preparation method thereof

Technical field:

The present invention relates to a kind of treatment vitiligo Chinese medicine and preparation method thereof.Relating in particular to a kind of treatment by oral administration of medicines prescription Zijin that with the Chinese herbal medicine is feedstock production treatment vitiligo is used looses and external treatment prescription Lithargyrum cream.

Background technology:

Leucoderma disease by universally acknowledged be dead person's " cancer " not.

At present the leukodermic main method of state's internal therapy has: methods such as ultraviolet radiation, pigment separations, subcutaneous injection, but most methods only cures the symptoms, not the disease, and also can recur in case stop to treat.The medicine that has has added hormone, makes the patient see curative effect in a short period of time, but so not only can't fundamentally thoroughly remove leucoderma disease, but also has a lot of side effect.Also have the Western medicine of some chemicals, side effect is big, and life-time service can bring very big misery for patient's body and mind to patient's the Liver and kidney two dirty infringements that cause in various degree.If will thoroughly cure leucoderma disease, must rely on the Chinese medicine and pharmacy technology, to regulate energy and blood of human body, heat clearing and blood circulation promoting the meridian dredging, strengthening the body resistance are main.Could fundamentally thoroughly cure this disease like this.

The leukodermic cause of disease is up to the present also not fully aware of, concludes and gets up to have following factor: inherited genetic factors; The neural factor of spirit; Chemical factor; The autoimmune factor; Melanocyte self-destruction factor; Endocrine factors; The tyrosine copper ion lacks factor relatively; Infective agent; Wound factor etc.As seen, leukodermic pathogenic factors is many-sided, but has quite a few patient to can not check any risk factor.At present from disease popularity aspect, minimum have following several factor can be described as to bring out leukodermic odjective cause:

(1) spiritual neuralization theory: a lot of clinical observations show spiritual neural factor and leukodermic confidential relation are arranged.2/3 case is arranged according to estimates approximately at onset or skin lesion developmental stage spiritedness wound, overworked, excessive thinking, weighed down with anxieties after being ill, even the then dream of feeling uneasy even when eating and sleeping, lie awake all night, sleep such as disturbs at spiritual hypertonicity situation.Vitiligo easily send out in be subjected to friction and outside the injury.Experiment confirm, near the white macula and on the normal skin of remote part through scratch grab stimulation after, can make this place whiteness of skin, and there is the variation of nerve fiber degeneration at the leucismus place.The patients with vitiligo autonomic nervous dysfunction of often occurring together.It is unusual to perspire as leucismus portion; With alopecia areata.

(2) theory of autoimmunity: autoimmune and vitiligo onset relation draw attention day by day.Notice that in recent years patient and relatives thereof can merge other autoimmune disease, also the someone finds the organ specific antibody of antithyroglobulin and anti-smooth muscle, anti-parietal cell or anti-adrenal tissue in the serum of patients with vitiligo, and recall rate obviously raises.And the general high 10-15 of crowd of autoimmune philtrum vitiligo incidence rate doubly.

(3) melanocyte self-destruction theory: leukodermic basic lesion be epidermal melanin cell part or loss of function completely, cause epidermis obviously to lack melanocyte and melanin granule.Intermediate material (or melanin precursor) in biosynthesis melanin (the comprising tyrosine) process is single phenol or Polyphenols.

(4) tyrosine, copper ion lack theory of factor relatively: melanic production process is the Biochemical processes of a complexity.And DOPA is a melanocyte is adrenergic predecessor, all derives from tyrosine, forms through the tyrosine oxidation.Can consume a large amount of adrenal hormones when psychentonia, this moment, DOPA mainly led adrenergic synthetic.Melanic therebetween synthetic will being affected.

(5) inherited genetic factors: have and think that primary disease may be a kind of dermatosis of autosomal dominant inheritance, AD.According to the foreign statistic data, the vitiligo sickness rate is about 18.75%-40% among the patients with vitiligo relatives, and between we the clinical experience 10%-20%, its positive rate more abroad is low.

In sum, leukodermic method of associated treatment and medicine are not also broken through so far, and the patient endures spirit and ailing torment to the fullest extent.

Summary of the invention:

The present invention overcomes the drawback of prior treatment method and medicine, according to pathogeny, adopts the Therapeutic Method of Orally taken and externally and reaches the purpose for the treatment of both the principal and secondary aspects of a disease.

For achieving the above object, the medicine that the present invention selects for use is to dispel the wind, hold concurrently and adjust human immune system and endocrine disturbance, thereby external application prescription Lithargyrum cream can effectively be repaired the human body skin melanocyte and promote melanin to generate the purpose that reaches healing with promoting flow of QI and blood, nourishing the liver and kidney, warming YANG spleen reinforcing.

Treatment by oral administration of medicines prescription Zijin of the present invention looses and is formed by following Chinese herbal medicine proportioning: 2 parts of the floating grass of the purple back of the body, 2 parts of Rhizoma Cibotiis, 1 part of Herba Schizonepetae, 1 part of Radix Saposhnikoviae, 1 part of Formica fusca, 1 part of Fructus Atriplicis Sibiricae, 1 part of Radix Clematidis, 2 parts of the Radixs Angelicae Dahuricae, 1 part of Squama Manis, 1 part of Radix Salviae Miltiorrhizae, 1 part of Rhizoma Chuanxiong, 1 part of the Radix Aucklandiae, 2 parts of Fructus Psoraleaes, 2 parts of Radix Polygoni Multiflori, 1 part of Herba Ecliptae, 1 part of the Rhizoma Atractylodis Macrocephalae, 1 part of Rhizoma Dioscoreae, 1 part of Massa Medicata Fermentata, 0.5 part in Radix Glycyrrhizae.

In above ratio compatibility, pulverize and be fine powder (or encapsulated), obey 5 grams, every day three times at every turn.Upper limb and trunk severe symptom are fried in shallow oil water for drawing with Rhizoma Et Radix Notopterygii 10 grams, take after meal.The heavy person of symptoms of lower extremity fries in shallow oil water for drawing with Radix Angelicae Pubescentis 10 grams, and take ante cibum.

External treatment prescription Lithargyrum cream of the present invention is formed by following Chinese herbal medicine proportioning: 3 parts of Lithargyrums, 2 parts of Fructus Psoraleaes, 1 part of the Radix Angelicae Dahuricae, 0.5 part of Calomelas, 2 parts in sulfur, 1 part of Pollen Typhae, 1 part of Fructus Gardeniae, 1 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of Fructus Mume, 1 part of Pyritum.

In above ratio compatibility, earlier with following herbal drug: Fructus Psoraleae, the Radix Angelicae Dahuricae, Pollen Typhae, Fructus Gardeniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Mume are fried and are deceived into charcoal, pulverize altogether and be superfine end, again Lithargyrum, Calomelas, Pyritum are respectively ground superfine end, more than each powder convert mixing together, with an amount of furnishing ointment of medical petrolatum oil, color ash duskiness.

Usage: fry in shallow oil water temperature with Radix Polygalae earlier and embrocate this cream, every day 2-3 time after deposited affected part 10-15 minute.

Attention:, must embrocate examination quick back application by first small size to the careful usefulness of hydrargyrum allergy sufferers.

Advantage of the present invention is:

It is raw material that the present invention selects natural Chinese medicine for use, according to the leucoderma disease etiopathogenesis, inside and outside rule together, compatibility is accurate, consumption is proper.Evident in efficacy, human body is not produced any toxic and side effects and harmful effect.

Specific embodiment:

Treatment by oral administration of medicines prescription Zijin looses and is formed by following Chinese herbal medicine proportioning: 2 parts of the floating grass of the purple back of the body, 2 parts of Rhizoma Cibotiis, 1 part of Herba Schizonepetae, 1 part of Radix Saposhnikoviae, 1 part of Formica fusca, 1 part of Fructus Atriplicis Sibiricae, 1 part of Radix Clematidis, 2 parts of the Radixs Angelicae Dahuricae, 1 part of Squama Manis, 1 part of Radix Salviae Miltiorrhizae, 1 part of Rhizoma Chuanxiong, 1 part of the Radix Aucklandiae, 2 parts of Fructus Psoraleaes, 2 parts of Radix Polygoni Multiflori, 1 part of Herba Ecliptae, 1 part of the Rhizoma Atractylodis Macrocephalae, 1 part of Rhizoma Dioscoreae, 1 part of Massa Medicata Fermentata, 0.5 part in Radix Glycyrrhizae.

Therapeutic effect example of the present invention:

The present invention was applied to so far clinical from 1993, implement treatment patients with vitiligo 107 examples.To adolescent patient effective percentage 100%, patient with slight symptoms three is to six months cure rates more than 90%.Follow the tracks of survey of patients and cure back nothing recurrence.

Claims

A kind of treatment by Chinese herbs vitiligo prescription and preparation method thereof

1. its feature of treatment by Chinese herbs vitiligo prescription and preparation method thereof: comprise that treatment by oral administration of medicines prescription Zijin looses and external treatment prescription Lithargyrum cream.
According to the described treatment by oral administration of medicines of claim 1 prescription Zijin loose by: 2 parts of the floating grass of the purple back of the body, 2 parts of Rhizoma Cibotiis, 1 part of Herba Schizonepetae, 1 part of Radix Saposhnikoviae, 1 part of Formica fusca, 1 part of Fructus Atriplicis Sibiricae, 1 part of Radix Clematidis, 2 parts of the Radixs Angelicae Dahuricae, 1 part of Squama Manis, 1 part of Radix Salviae Miltiorrhizae, 1 part of Rhizoma Chuanxiong, 1 part of the Radix Aucklandiae, 2 parts of Fructus Psoraleaes, 2 parts of Radix Polygoni Multiflori, 1 part of Herba Ecliptae, 1 part of the Rhizoma Atractylodis Macrocephalae, 1 part of Rhizoma Dioscoreae, 1 part of Massa Medicata Fermentata, Radix Glycyrrhizae are formed for 0.5 part.
3. loose in above ratio compatibility according to claim 1,2 described treatment by oral administration of medicines prescription Zijins, pulverize and be fine powder (or encapsulated), upper limb and trunk severe symptom restrain with Rhizoma Et Radix Notopterygii 10 and fry in shallow oil water for drawing, and take after meal.
4. loose and be fine powder (or encapsulated) in above ratio compatibility pulverizing according to claim 1,2 described treatment by oral administration of medicines prescription Zijins, the heavy person of symptoms of lower extremity fries in shallow oil water for drawing with Radix Angelicae Pubescentis 10 grams, and take ante cibum.
According to the described external treatment of claim 1 prescription Lithargyrum cream by: 3 parts of Lithargyrums, 2 parts of Fructus Psoraleaes, 1 part of the Radix Angelicae Dahuricae, 0.5 part of Calomelas, 2 parts in sulfur, 1 part of Pollen Typhae, 1 part of Fructus Gardeniae, 1 part of the Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of Fructus Mume, Pyritum are formed for 1 part.
6. fill a prescription the Lithargyrum cream in above ratio compatibility according to claim 1,5 described external treatment, earlier with following herbal drug: Fructus Psoraleae, the Radix Angelicae Dahuricae, Pollen Typhae, Fructus Gardeniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Mume are fried and are deceived into charcoal, pulverize altogether and be superfine end, again Lithargyrum, Calomelas, Pyritum are respectively ground superfine end, more than each powder convert mixing together, with an amount of furnishing ointment of medical petrolatum oil, color ash duskiness.
According to claim 1,2,3,4,5,6 described be that raw material treatment vitiligo prescription and preparation method thereof is all at this claim protection domain with Chinese medicine.