CN101214403A - Light emitting diode light therapeutic instruments - Google Patents

Light emitting diode light therapeutic instruments Download PDF

Info

Publication number
CN101214403A
CN101214403A CNA2007100971886A CN200710097188A CN101214403A CN 101214403 A CN101214403 A CN 101214403A CN A2007100971886 A CNA2007100971886 A CN A2007100971886A CN 200710097188 A CN200710097188 A CN 200710097188A CN 101214403 A CN101214403 A CN 101214403A
Authority
CN
China
Prior art keywords
light
photo
emitting diode
light emitting
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CNA2007100971886A
Other languages
Chinese (zh)
Other versions
CN100591394C (en
Inventor
魏勋斌
张占详
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Caihong Communication Co Ltd
Fudan University
Original Assignee
Caihong Communication Co Ltd
Fudan University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caihong Communication Co Ltd, Fudan University filed Critical Caihong Communication Co Ltd
Priority to CN200710097188A priority Critical patent/CN100591394C/en
Publication of CN101214403A publication Critical patent/CN101214403A/en
Application granted granted Critical
Publication of CN100591394C publication Critical patent/CN100591394C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Abstract

The invention provides an LED light therapeutic apparatus, the probe of which can include a special lens array combination to strengthen the illumination effect; a blue LED and a red LED are combined as the light source of the LED light therapeutic apparatus; and a light beam deformation thin or mechanical pupillar is used for regulating the shape or size of the illumination treatment zone.

Description

A kind of light emitting diode light therapeutic instruments
Technical field
The present invention relates to treatment of department of dermatologry light or beautifying technique field, be specifically related to a kind of structure of light emitting diode light therapeutic instruments.
Background technology
Acne is a kind of disease of sebaceous glands, and clinical symptoms has, sebum distortion, exfoliation and inflammation.A variety of factors can cause the formation of acne, for example bacteria breed; Over-exposure is under solar ulatraviolet radiation; Be in adolescence teenager of a large amount of hormones of secretion or the like.Fig. 1 has shown the forming process of acne.
Usually the first-selected antibiotic of doctor is as the method for treatment acne, or is used in combination old-fashioned near infrared-ray treating device, and its process as shown in Figure 2.But because antibiotic often taking brought Drug resistance, the not good and side effect in addition of many patients' therapeutic effect.
Acne malignant bacteria skin ulcer bleb propanoic acid Propiobacterium (P.Acne) contains a large amount of porphyrins, and porphyrin has very strong absorption on wavelength 410nm, porphyrin shown in the following formula I has powerful absorption band near wavelength 410nm, this absorption band is called the Soret band, see also typical ultraviolet shown in Figure 3 to visible PROPHYRIN (porphyrin) light absorption line, wherein being the strong Soret band that absorbs near the 410nm, is 4 Q bands that indicate with digital IV-I subsequently.When the rayed acne of certain wavelength, the light of wavelength about 410nm will be easy to be absorbed by the porphyrin in the malignant bacteria of acne, this absorption process can be brought corresponding photochemical reaction, for example, produce the free radicals such as single oxygen of energy killing bacteria behind the porphyrin absorption light, to kill the antibacterial at acne position effectively, and make the ruined organized renewing in acne position normal.
Figure A20071009718800061
This shows that photodynamic therapy is effective for acne.In an about century, the light source of many types is used to treat acne.Comprising the fluorescent lamp, Halogen light, tengsten lamp and laser in recent years and light emitting diode.Main company and product have been enumerated in the following table 1.
Table 1 is used the dominant company and the product of laser and light source principle treatment acne
Light source Manufacturer Model Parameter Target/chromatophore
Fluorescent lamp Sylvania HF 885 415nm P.acnes
Fluorescent lamp 660-nm P.acnes
Full spectral light Philips HPA 400W Visible light and ultraviolet light,long wave P.acnes
Green glow Philips Thalium The 470-nm filter P.acnes
Purple light Philips HPM-10 The 390-nm filter P.acnes
Blue metal halide lamp CureLight 407 to 420nm P.acnes
The xenon flashing lamp Radiancy ClearTouch 430 to 1200nm P.acnes
Laser Candela Smoothbeam 1450nm Sebaceous gland
Laser Cynosure PhotoGenica 595nm Oxyhemoglobin
Laser Cynosure Unknown 800-nm+ICG * Sebaceous gland
*The ICG=indocyanine green.
High strength, the narrow-band blue light light source of amplification (Cure Light) are used for treating the acne of slight and moderate.The blue light of this therapy apparatus output high-power, output wavelength arrives 420nm, power density 90mw/cm 407 2. can cure face, the acne of back and chest.
Another cries the pulse output wavelength of therapy equipment of Clear Touch between 430 to 1200nm, and wherein gold-tinted and green glow 500 to 600nm can reach several millimeters by skin permeation.
Light emitting diode photodynamic therapy technology (Light Emitting Diode-Photo DynamicTherapy, LED-PDT) treatment technology is a rising in recent years, with light emitting diode and semiconductor laser be light source be used for treat and diagnose a kind of novel medical, health care and beautifying technique.At the characteristic and the advantage of this technology, can design and develop treatment, diagnostic machine usually according to demand into numerous species.Be used in the treatment cutaneous diseases at present, promote the diagnosis of the healing of bodily tissue wound and tissue regeneration and disease of eye and analyze three aspects most popular.And being used for beauty treatment and fat-reducing, the demand that smoothes away wrinkles is also heightening.Along with the structural design of light emitting diode photodynamic therapy machine, the updating and improve doctor and patient and can further increase of date processing and technological process to this demand.
The commonly encountered diseases of department of dermatologry, acne for example, butterfly spot, vitiligo, skin allergy inflammation that the skin over-exposure causes under sunlight and ultraviolet or the like usually owing to can not get effectively, is treated timely and is let slip a golden opportunity.Most of people have acne, because have bacteria breed in various degree on everyone skin.Acne is to cause the common disease of chafing, particularly at the first half of facial and health.The skin carcinoma that accounts for the second largest cause of the death of cancer in the U.S. has nearly 40% to damage skin keratin by photochemistry and cause.Because skin produces photochemical effect, usually can on facial and scalp, occur coarse, fish scale shape, white symptoms such as speckle.This class that seriously is of problem is subjected to photochemical effect skin to tend to develop into skin carcinoma.
Three medical institutions that the U.S. is main, American Cancer Society is if skin cancer foundation and the suggestion of U.S. department of dermatologry institute it is found that oneself have the photochemical symptom of cutin to see the doctor for treatment immediately.Therefore owing to producing the frequency that photochemical reaction goes to see the doctor under sunlight and ultraviolet, the skin over-exposure comes the 3rd in the U.S..Because the demand of this respect, Food and Drug Administration has ratified also there be not the skin keratin that plays photochemical effect of keratinization to avoid the generation of cancer with light emitting diode-photodynamics blue-light treatment recently.Ultraviolet light is prejudicial to skin, but the light of not all wavelength is all as ultraviolet light.The skin that opposite suitable selective light wavelength can be treated and be recovered to be damaged.One of technology of research light emitting diode and laser therapeutic apparatus key is exactly to select optimal light wavelength and luminous power.
Photodynamic therapy is that a main innovation is used for treating potential cases with severe in conjunction with blue light and topical remedy.Breadboard treatment data show, use the light emitting diode instrument for treating acne, and 70% sufferer is being fully recovered through after the treatment in 12 week of phase I.The treatment of second stage also need be treated for 8 week more if desired.Through the treatment in the one the second two stages, 88% sufferer can be cured original skin more than 75% of cutin photochemistry symptom, both pachylosiies, and white point disappears.94% patient is with deep impression to therapy apparatus.Reflection is good.84% patient is ready need also can reuse light emitting diode-photodynamic therapy machine if having from now on.
The characteristics and the advantage of this class therapeutic instrument are as follows: therapeutic effect is fast, do not need anesthesia, nonpain treatment, have no side effect, each about 20 minutes of treatment time, be used safely in the chemical reaction exfoliating skin, the acne of the excessive and other type of solar radiation, be applicable to any age, sex, the skin of any kind of includes Pigmented skin.
Yet in existing light emitting diode and laser diagnosis and treatment acne technology, equally yet there is following various problems:
At first, existing light emitting diode and laser diagnosis and treatment acne technology are just at acne bacteria itself, for example only be to use blue light clinically, and bacterial inflammation symptom is not directly handled, so clinical effectiveness is not rapid usually, for example need week age just can embody effect, rather than take effect in a couple of days.This situation is disadvantageous for treatment.
Secondly, present light emitting diode and laser diagnosis and treatment acne technology are having tangible deficiency aspect the shape of light area, the dimension adjustable, and the shape of light area, size directly have influence on curative effect.Be applied to clinical in, the difficult different needs of existing technology with the acne patient that satisfies different situations.
In addition, currently used therapeutic instrument is all bulky usually, has only the use of just having ready conditions of special places such as hospital, and needs professional's maintenance and operation in addition, obviously influences the popularization and the use of this kind treatment technology.
Therefore, be necessary to occur photo-therapeutic instrument a kind of easy to use, respond well and safe.
Summary of the invention
At the every problem that exists in the prior art the present invention is proposed.The object of the present invention is to provide a kind of volume little, price is low, safe and reliable and LED source therapeutic instrument that therapeutic effect is good.
When using laser and light emitting diode light treatment acne, light source can be launched continuously and the light of pulse.The output of continuous light source light is stable but peak power is low.The light source of pulse is owing to the peak power height, and the time of treatment irradiation can be very short.For example pulse width 35ms exports energy 3.5J/cm 2The light source power ratio be 100,00mw/cm 2And the power ratio of the continuous light source of identical wavelength is 10mw/cm 2The photon output that is light-pulse generator is 10000 times of continuous light source.Though light intensity is different, no matter use any light source, organizing irradiated energy is the same in the scope at one time.
Ultraviolet light,long wave and UV-B have better curative effect to remedy of acne, but have carcinogenic danger, comparatively speaking, use blue light and red light-emitting diode treatment acne safer among the present invention, and have effect preferably equally, effect is more remarkable when being used alternatingly.As for HONGGUANG or blue light, still two kinds of light sources play a role in acne treatment simultaneously, not limited by prior theory.Confirmablely in the present invention be that with blue light 450nm with HONGGUANG 630nm is used and use blue light to compare separately, the former more produces effect in the slight and moderate acne process in treatment.According to inventor's finding, will use for example blue light-emitting diode and the 633nm red light-emitting diode of 410nm in the present invention, or with the near-infrared luminous diode design of 830nm with make photo-therapeutic instrument efficiently.
Technical specification about blue light-emitting diode is as shown in table 2 below:
Table 2 blue-ray LED technical specification
Output 600 milliwatts
Power density 50 milliwatt/square centimeters
Output wavelength 405+/-5 nanometers
Bandwidth 22 nanometers+/-3 nanometers
48 joules/square centimeter of standard doses
Treatment time 10-30 minute
Dosage range 1-55 joule/square centimeter
Light source analogy light emitting diode (LED)
Weight 450 grams
50/63/170 millimeter of volume
The critical piece of light emitting diode light therapeutic instruments of the present invention comprises: the photo-therapeutic instrument main body and the light outgoing parts (i.e. probe) that comprise Power Supply Assembly.
Photo-therapeutic instrument adopts light emitting diode subsection light source, is combined by blue LED and red light emitting diodes, and light emitted energy density is 20-200 milliwatt/square centimeter.Wherein the optical wavelength of blue LED emission is 400-420nm, and the optical wavelength of red light emitting diodes emission is 600-850nm.When being applied to processes such as skin care or beauty treatment, blue LED is mainly used in killing bacteria, and red light emitting diodes is mainly used in the dephlogistication symptom.It will be understood by those of skill in the art that in photo-therapeutic instrument of the present invention, parameters such as light emitted wavelength, power can be selected according to actual needs so long as for above-mentioned purpose.
The probe of described light emitting diode light therapeutic instruments includes a special lens arra combination, wherein comprises a plurality of lenslets.The array combination of this lenslet can effectively be collected the light that sends from each light emitting diode subsection light source of photo-therapeutic instrument inside, the concrete mode of described lens arra combination can be, the polygon array that is combined into by a plurality of lens arrangement, hexagon planar array for example, octagon planar array, perhaps circular flat array.In fact, the array shape of lens and the lenslet number of use all can be looked actual demand and adjusted.Above-mentioned lens arra is fixed on the panel, and whole lens arra can be embedded in the probe of photo-therapeutic instrument with panel.
Because the existence of lens arra, the inner outwards emission of probe from the light of each light emitting diode subsection light source at first the scioptics array just arrive the irradiation target, the illumination energy density that direct effect is illuminated into treatment sites obtains increasing, and promotes the curative effect of photo-therapeutic instrument; Correspondingly, because energy passes through converging of lens arra and distributes, its loss can reduce, and it is simpler and low-cost that the electric power system of whole therapeutic instrument and heat treatment system also can become.
Except above-mentioned lens arra, the probe of light emitting diode light therapeutic instruments of the present invention also has the light beam anamorphoser, described light beam anamorphoser is the thin film that is covered on the lens arra, when light during from the lens arra outgoing, by described thin film, promptly the light beam anamorphoser just arrives the irradiation target earlier.The effect of light beam anamorphoser is the shape that changes the light area, and light can become circle at an easy rate by after the light beam anamorphoser, oval or other shape.Described light area shape variable voltinism makes the be content with very little acne patient needs of different situations, different irradiated sites of photo-therapeutic instrument.
Above-mentioned light beam distortion thin film as the light beam anamorphoser can design by holographic beam diffusion technique and light beam distortion to be produced, these contents can be with reference to sophisticated prior art, and described light beam anamorphoser thin film also can have been bought on market.For the present invention, purpose only is to reach the light beam that makes the outgoing of light-emitting-diode therapeutic instrument and changes shape, therefore at this light beam modification thin film technique is not described further.Certainly, it will be understood by those of skill in the art that this light beam distortion thin film also can carry out conventional design on the prior art basis for specific requirement of the present invention.For example, because the led array light source is not a single source, light beam distortion thin film also should be designed to be different from the situation of using on the single light source.Described film thickness is generally in the millimeter rank.Be applied to when of the present invention, light beam distortion thin film directly is installed on the light outgoing path of photo-therapeutic instrument with a holder, presses close to lens arra.
Light emitting diode light therapeutic instruments of the present invention also has mechanical pupil device, is installed on the beam projecting position of probe, and the size of a switch scalable pupil is arranged on it, and when mechanical coreclisis, light path is blocked, and the light of light emitting diode can not outgoing; When the open-shaped attitude of mechanical pupil, can be by regulating the size that size that this mechanical pupil opens the hole is regulated the formed photo-irradiation treatment of emergent ray zone.The size adjustment in photo-irradiation treatment zone can satisfy the demand of different acne patients in the actual therapeutic process equally.
Need the consideration of oxygen supply for the photochemical reaction of physiology self regulation function that strengthens human body in actual use and porphyrin absorption blue light killing bacteria, light emitting diode light therapeutic instruments of the present invention can be set light-struck ON/OFF cycle and frequency, specifically be set to: for example, switch periods is 0.5 hertz~5 hertz, and open/close time portion ratio is 2: 1~1: 2.
On the other hand, in order to make luminous energy transdermal top layer and arrive and make use more deeply, it is bacterial infection inflammation place, certain shape and size are taked in the irradiation head design of light emitting diode light therapeutic instruments of the present invention, and lens arra and light spot shape manipulator can design according to situation about will treat.Concrete example can be, for example hexagon, octagon, circular or the like.
When using laser and light emitting diode light therapeutic instruments treatment acne, no matter LED blue light or HONGGUANG are that use separately or alternating treatment are all very effective on the one hand, particularly, when the two is combined treatment, can present and take effect rapidly, than the more perfect advantage of single Use Limitation fruit.
Description of drawings:
The accompanying drawing that comprises among the application is a component part of description, and accompanying drawing and description and claims one are used from explanation flesh and blood of the present invention, are used for understanding better the present invention.
Fig. 1 is the forming process sketch map of acne;
Fig. 2 is the process sketch map of acne treatment;
Fig. 3 is that typical ultraviolet is to visible PROPHYRIN (porphyrin) light absorption line;
Fig. 4 has shown a kind of overall schematic according to portable light emitting diode light therapeutic instruments of the present invention;
Fig. 5 a has shown the power supply dependency structure of photo-therapeutic instrument shown in Figure 4;
Fig. 5 b has shown the view of above-mentioned photo-therapeutic instrument when charging;
Fig. 6 is the sketch map of lens arra compositions panel;
Fig. 7 is the sketch map of photo-therapeutic instrument assembling light beam distortion thin film; With
Fig. 8 is the sketch map of mechanical pupil.
Description of reference numerals:
1 portable light emitting diode light therapeutic instruments
11 bodies
111 times were provided with switch
112 start buttons
113 charging indicator lights
114 low electric weight display lamps
115 set of cells
116 charging inlets
117 on and off switch
12 probes
121 lens arra assembled panels
122 light beams distortion thin film
2 charging pedestals
The specific embodiment
The present invention is further elaborated below in conjunction with embodiment, but these embodiment do not constitute any restriction to the present invention.
Embodiment 1
The structure of portable light emitting diode light therapeutic instruments
See also the overall schematic of portable light emitting diode light therapeutic instruments (hereinafter to be referred as photo-therapeutic instrument) shown in Figure 4.
Photo-therapeutic instrument 1 comprises body 11 and probe 12, has the time on the panel of body 11 switch 111 is set, and is used to set the light application time of photo-therapeutic instrument 1 when user mode; Start button 112 is used to start photo-therapeutic instrument; Charging indicator light 113 is used to indicate charged state; With low electric weight display lamp 114, be used to indicate low state of charge.
This photo-therapeutic instrument uses compact power, sees also the photo-therapeutic instrument power supply dependency structure sketch map shown in Fig. 5 a, and body 11 back sides of photo-therapeutic instrument 1 have on and off switch 117, are used to open or close the power supply of photo-therapeutic instrument; Set of cells 115 is arranged in the body 11, be used for powering to photo-therapeutic instrument; Set of cells 115 can connect external power source by the charging inlet on the body 11 116, charges.
The view that Fig. 5 b is this photo-therapeutic instrument when charging, as shown in the figure, photo-therapeutic instrument 1 engages with the pedestal 2 that charges by the charging inlet (not shown) on the body, and 2 of pedestals link to each other with conventional supply socket by transformator.
In the present embodiment, photo-therapeutic instrument adopts light emitting diode subsection light source, is combined by blue LED and red light emitting diodes, and light emitted energy density is 20-200 milliwatt/square centimeter.Wherein the optical wavelength of blue LED emission is 400-420nm, and the optical wavelength of red light emitting diodes emission is 600-850nm.When being applied to processes such as skin care or beauty treatment, blue LED is mainly used in killing bacteria, and red light emitting diodes is mainly used in the dephlogistication symptom.The parameter area that it will be understood by those of skill in the art that among the embodiment is provided is not construed as limiting, and in photo-therapeutic instrument of the present invention, parameters such as light emitted wavelength, power can be selected according to actual needs.
The probe 12 of photo-therapeutic instrument includes lens arra assembled panel 121, as shown in Figure 6, described lens arra assembled panel 121 as shown in Figure 6, panel comprises the hexagon planar array that 30 lenslets are formed.Described lens arra assembled panel 121 is positioned on the light outgoing path of photo-therapeutic instrument probe, makes the effect of the light of the inner outgoing of photo-therapeutic instrument through lens arra, and its actual installation site is 5a with reference to the accompanying drawings.
The array combination of above-mentioned 30 lenslets can effectively be collected the light that sends from each light emitting diode subsection light source of photo-therapeutic instrument inside, can make the illumination energy density of illuminated into treatment sites obtain increasing, and promotes the curative effect of photo-therapeutic instrument; Correspondingly, because energy passes through converging of lens arra and distributes, its loss can reduce, and it is simpler and low-cost that the electric power system of whole therapeutic instrument and heat treatment system also can become.Should be noted that, though provided the concrete mode of lens arra combination in the present embodiment, but the polygon array that is combined into by a plurality of lens arrangement that meets this technical scheme original intention, also be included in the category of the present invention, pentagon planar array for example, hexagon planar array, octagon planar array etc., perhaps circular flat array, and the lenslet quantity of correspondingly using in array etc. all can be looked actual needs and adjust.
The probe of photo-therapeutic instrument has also used light beam distortion thin film, and as shown in Figure 7, light beam distortion thin film 122 is positioned on the light outgoing path of photo-therapeutic instrument probe 12, is used to change the shape that emergent light forms the photo-irradiation treatment zone.
This light beam distortion thin film can become circle with the shape in photo-irradiation treatment zone, oval or other shape.Light area shape variable voltinism makes the be content with very little acne patient needs of different situations, different irradiated sites of photo-therapeutic instrument.
The light beam of light beam anamorphoser distortion thin film can design by holographic beam diffusion technique and light beam distortion and produce, and these contents can be with reference to sophisticated prior art, and described light beam anamorphoser thin film also can have been bought on market.For the present invention, purpose only is to reach the light beam that makes the outgoing of light-emitting-diode therapeutic instrument and changes shape, therefore at this light beam modification thin film technique is not described further.Certainly, it will be understood by those of skill in the art that this light beam distortion thin film also can carry out conventional design on the prior art basis for specific requirement of the present invention.For example, because the led array light source is not a single source, light beam distortion thin film also should be designed to be different from the situation of using on the single light source.Described film thickness is generally in the millimeter rank.When being applied to present embodiment, light beam distortion thin film directly is installed on the light outgoing path of photo-therapeutic instrument with a holder, presses close to lens arra.
The probe of photo-therapeutic instrument is equipped with mechanical pupil, and this machinery pupil is positioned on the light outgoing path of photo-therapeutic instrument probe, can regulate the size that emergent light forms the photo-irradiation treatment zone by switch.Described mechanical pupil as shown in Figure 8.The size that the machinery pupil can be regulated pupil by switch.When mechanical coreclisis, light path is blocked, and the light of light emitting diode can not outgoing; When the open-shaped attitude of mechanical pupil, can be by regulating the size that size that this mechanical pupil opens the hole is regulated the formed photo-irradiation treatment of emergent ray zone.The size adjustment in photo-irradiation treatment zone can satisfy the demand of different acne patients in the actual therapeutic process equally.
Need the consideration of oxygen supply for the photochemical reaction of physiology self regulation function that strengthens human body in actual use and porphyrin absorption blue light killing bacteria, light emitting diode light therapeutic instruments of the present invention can be set light-struck ON/OFF cycle and frequency, specifically be set to: for example, switch periods is 0.5 hertz~5 hertz, and open/close time portion ratio is 2: 1~1: 2.
On the other hand, in order to make luminous energy transdermal top layer and arrive and make use more deeply, it is bacterial infection inflammation place, certain shape and size are taked in the irradiation head design of light emitting diode light therapeutic instruments of the present invention, and lens arra and light spot shape manipulator can design according to situation about will treat.Concrete example can be, for example hexagon, octagon, circular or the like.
Embodiment 2
The clinical effectiveness of photo-therapeutic instrument
Voluntary user (face) has been carried out the research of four stars phase with embodiment 1 described portable light emitting diode phototherapy instrument.The result is as follows:
Illustrate: 1) be divided into two kinds (inflammatory and non-inflammatory) because of the acne type.Each patients with acne is general existing inflammatory, and non-inflammatory acne is also arranged.Under study for action each inflammatory and non-inflammatory acne of voluntary user face phototherapy processing, the line trace of going forward side by side have all been carried out.But in following table, inflammatory acne of face and non-inflammatory acne number are carried out statistical disposition (acne has disappeared then, and counting is 0) respectively.
Table 3) total inflammatory acne number over time situation (every group of number is 5, and matched group is for being left intact; For more convenient, total inflammatory acne number is 100 by standardization (Normalize) before the treatment; Standard variance=+/-5)
Group the time Before the treatment After treating a week After treating for two weeks Treatment Samsung after date Treatment four stars after date
The treatment group 100 79 58 54 51
Matched group 100 92 83 77 72
Table 4) total non-inflammatory acne number over time situation (every group of number is 5, and matched group is for being left intact; For more convenient, the acne number is 100 by standardization (Normalize) before the treatment; Standard variance=+/-5)
Group the time Before the treatment After treating a week After treating for two weeks Treatment Samsung after date Treatment four stars after date
The treatment group 100 93 88 85 82
Matched group 100 97 94 93 91
Conclusion: Phototherapeutic instrument of the present invention has obvious effects (to see Table 3 to the treatment of inflammatory acne; Compare with matched group).Though and Phototherapeutic instrument has certain effect to the treatment of non-inflammatory acne, compares with matched group (seeing Table 4), does not have the difference on the tangible statistics.

Claims (28)

1. light emitting diode light therapeutic instruments, it is characterized in that, the probe of photo-therapeutic instrument has lens arra, the planar array that described lens arra is made up of on same panel a plurality of lens, this panel that contains lens arra is positioned on the light outgoing path of photo-therapeutic instrument probe, makes the effect of the light of the inner outgoing of photo-therapeutic instrument through lens arra.
2. light emitting diode light therapeutic instruments as claimed in claim 1 is characterized in that described lens arra comprises the pentagon planar array at least, hexagon planar array, octagon planar array and circular flat array.
3. light emitting diode light therapeutic instruments as claimed in claim 2 is characterized in that, the hexagon planar array that described lens arra is made up of 30 lens.
4. light emitting diode light therapeutic instruments as claimed in claim 1 is characterized in that, described photo-therapeutic instrument is that blue LED and red light emitting diodes are combined as the light source of light emitting diode light therapeutic instruments.
5. light emitting diode light therapeutic instruments as claimed in claim 4 is characterized in that, described blue LED wavelength of transmitted light scope is 400~420nm, and red light emitting diodes wavelength of transmitted light scope is 600-850nm.
6. light emitting diode light therapeutic instruments as claimed in claim 1, it is characterized in that, the probe of photo-therapeutic instrument has light beam distortion thin film, and this light beam distortion thin film is positioned on the light outgoing path of photo-therapeutic instrument probe, is used to change the shape that emergent light forms the photo-irradiation treatment zone.
7. light emitting diode light therapeutic instruments as claimed in claim 1 is characterized in that the probe of photo-therapeutic instrument has mechanical pupil, and this machinery pupil is positioned on the light outgoing path of photo-therapeutic instrument probe, is used to regulate the size that emergent light forms the photo-irradiation treatment zone.
8. as any described light emitting diode light therapeutic instruments in the claim 1~7, it is characterized in that described photo-therapeutic instrument has the device of setting ON/OFF cycle and rayed frequency.
9. light emitting diode light therapeutic instruments as claimed in claim 8 is characterized in that, the time portion ratio in described ON/OFF cycle is 2: 1~1: 2, and frequency is 0.5 hertz~5 hertz.
10. as any described light emitting diode light therapeutic instruments in the claim 1~7, it is characterized in that the radiative energy density of described photo-therapeutic instrument is 20~200 milliwatt/square centimeters.
11. a light emitting diode light therapeutic instruments is characterized in that, described photo-therapeutic instrument is that blue LED and red light emitting diodes are combined as the light source of light emitting diode light therapeutic instruments;
The probe of photo-therapeutic instrument has following parts:
Lens arra, the planar array that described lens arra is made up of on same panel a plurality of lens, this panel that contains lens arra is positioned on the light outgoing path of photo-therapeutic instrument probe, makes the effect of the light of the inner outgoing of photo-therapeutic instrument through lens arra;
Light beam distortion thin film, this light beam distortion thin film is positioned on the light outgoing path of photo-therapeutic instrument probe, obtains changing the photo-irradiation treatment zone of shape through the effect of light beam distortion thin film from the light of the inner outgoing of photo-therapeutic instrument.
12. light emitting diode light therapeutic instruments as claimed in claim 11 is characterized in that, described lens arra comprises the pentagon planar array at least, hexagon planar array, octagon planar array and circular flat array.
13. light emitting diode light therapeutic instruments as claimed in claim 12 is characterized in that, the hexagon planar array that described lens arra is made up of 30 lens.
14., it is characterized in that described photo-therapeutic instrument has the device of setting ON/OFF cycle and rayed frequency as any described light emitting diode light therapeutic instruments in the claim 11~13.
15. light emitting diode light therapeutic instruments as claimed in claim 14 is characterized in that, the time portion ratio in described ON/OFF cycle is 2: 1~1: 2, and the rayed frequency is 0.5 hertz~5 hertz.
16., it is characterized in that the radiative energy density of described photo-therapeutic instrument is 20~200 milliwatt/square centimeters as any described light emitting diode light therapeutic instruments in the claim 11~13.
17. a light emitting diode light therapeutic instruments is characterized in that, described photo-therapeutic instrument is that blue LED and red light emitting diodes are combined as the light source of light emitting diode light therapeutic instruments;
The probe of photo-therapeutic instrument has following parts:
Lens arra, the planar array that described lens arra is made up of on same panel a plurality of lens, this panel that contains lens arra is positioned on the light outgoing path of photo-therapeutic instrument probe, makes the effect of the light of the inner outgoing of photo-therapeutic instrument through lens arra;
The machinery pupil, this machinery pupil is positioned on the light outgoing path of photo-therapeutic instrument probe, is used to regulate the size that emergent light forms the photo-irradiation treatment zone.
18. light emitting diode light therapeutic instruments as claimed in claim 17 is characterized in that, described lens arra comprises the pentagon planar array at least, hexagon planar array, octagon planar array and circular flat array.
19. light emitting diode light therapeutic instruments as claimed in claim 18 is characterized in that, the hexagon planar array that described lens arra is made up of 30 lens.
20., it is characterized in that described photo-therapeutic instrument has the device of setting ON/OFF cycle and rayed frequency as any described light emitting diode light therapeutic instruments in the claim 17~19.
21. light emitting diode light therapeutic instruments as claimed in claim 20 is characterized in that, the time portion ratio in described ON/OFF cycle is 2: 1~1: 2, and the rayed frequency is 0.5 hertz~5 hertz.。
22., it is characterized in that the radiative energy density of described photo-therapeutic instrument is 20~200 milliwatt/square centimeters as any described light emitting diode light therapeutic instruments in the claim 17~19.
23. a light emitting diode light therapeutic instruments is characterized in that, described photo-therapeutic instrument is that blue LED and red light emitting diodes are combined as the light source of light emitting diode light therapeutic instruments;
The probe of photo-therapeutic instrument has following parts:
Lens arra, the planar array that described lens arra is made up of on same panel a plurality of lens, this panel that contains lens arra is positioned on the light outgoing path of photo-therapeutic instrument probe, makes the effect of the light of the inner outgoing of photo-therapeutic instrument through lens arra;
Light beam distortion thin film, this light beam distortion thin film is positioned on the light outgoing path of photo-therapeutic instrument probe, obtains changing the photo-irradiation treatment zone of shape through the effect of light beam distortion thin film from the light of the inner outgoing of photo-therapeutic instrument;
The machinery pupil, this machinery pupil is positioned on the light outgoing path of photo-therapeutic instrument probe, is used to regulate the size that emergent light forms the photo-irradiation treatment zone.
24. light emitting diode light therapeutic instruments as claimed in claim 23 is characterized in that, described lens arra comprises the pentagon planar array at least, hexagon planar array, octagon planar array and circular flat array.
25. light emitting diode light therapeutic instruments as claimed in claim 24 is characterized in that, the hexagon planar array that described lens arra is made up of 30 lens.
26., it is characterized in that described photo-therapeutic instrument has the device of setting ON/OFF cycle and rayed frequency as any described light emitting diode light therapeutic instruments in the claim 23~25.
27. light emitting diode light therapeutic instruments as claimed in claim 26 is characterized in that, the time portion ratio in described ON/OFF cycle is 2: 1~1: 2, and the rayed frequency is 0.5 hertz~5 hertz.。
28., it is characterized in that the radiative energy density of described photo-therapeutic instrument is 20~200 milliwatt/square centimeters as any described light emitting diode light therapeutic instruments in the claim 23~25.
CN200710097188A 2007-01-05 2007-04-12 Light emitting diode light therapeutic instruments Expired - Fee Related CN100591394C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200710097188A CN100591394C (en) 2007-01-05 2007-04-12 Light emitting diode light therapeutic instruments

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200710036243 2007-01-05
CN200710036243.0 2007-01-05
CN200710097188A CN100591394C (en) 2007-01-05 2007-04-12 Light emitting diode light therapeutic instruments

Publications (2)

Publication Number Publication Date
CN101214403A true CN101214403A (en) 2008-07-09
CN100591394C CN100591394C (en) 2010-02-24

Family

ID=39620947

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200710097188A Expired - Fee Related CN100591394C (en) 2007-01-05 2007-04-12 Light emitting diode light therapeutic instruments

Country Status (1)

Country Link
CN (1) CN100591394C (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101889859A (en) * 2010-08-18 2010-11-24 天津市同业科技发展有限公司 LED wood lamp
CN105233423A (en) * 2015-07-20 2016-01-13 云南极粹生物科技有限公司 Intelligent laser therapy bracelet and control method thereof
CN105363132A (en) * 2014-08-14 2016-03-02 中央大学 UVB-LED portable automatic tracking psoriasis treatment machine
CN105381546A (en) * 2015-10-27 2016-03-09 何江思 Vitiligo treatment instrument
CN105944236A (en) * 2016-05-23 2016-09-21 宿州市埇桥区善堂白癜风研究所 Light kinetic energy leucoderma therapeutic instrument with 380nm spectrum
WO2016184441A1 (en) 2015-05-18 2016-11-24 Univerzita Palackého v Olomouci Planar irradiation source especially for induction and monitoring of photodynamic effect in vitro
CN109663215A (en) * 2018-12-19 2019-04-23 广州联合群美进出口有限公司 A kind of laser anti-acne pen
CN110339473A (en) * 2019-07-12 2019-10-18 浙江赛美克电子科技有限公司 A kind of multifunctional portable beauty-care physiotherapy box

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101889859A (en) * 2010-08-18 2010-11-24 天津市同业科技发展有限公司 LED wood lamp
CN105363132A (en) * 2014-08-14 2016-03-02 中央大学 UVB-LED portable automatic tracking psoriasis treatment machine
WO2016184441A1 (en) 2015-05-18 2016-11-24 Univerzita Palackého v Olomouci Planar irradiation source especially for induction and monitoring of photodynamic effect in vitro
CN105233423A (en) * 2015-07-20 2016-01-13 云南极粹生物科技有限公司 Intelligent laser therapy bracelet and control method thereof
CN105381546A (en) * 2015-10-27 2016-03-09 何江思 Vitiligo treatment instrument
CN105381546B (en) * 2015-10-27 2018-03-23 何江思 A kind of leucoderma therapeutic equipment
CN105944236A (en) * 2016-05-23 2016-09-21 宿州市埇桥区善堂白癜风研究所 Light kinetic energy leucoderma therapeutic instrument with 380nm spectrum
CN109663215A (en) * 2018-12-19 2019-04-23 广州联合群美进出口有限公司 A kind of laser anti-acne pen
CN110339473A (en) * 2019-07-12 2019-10-18 浙江赛美克电子科技有限公司 A kind of multifunctional portable beauty-care physiotherapy box

Also Published As

Publication number Publication date
CN100591394C (en) 2010-02-24

Similar Documents

Publication Publication Date Title
CN100591394C (en) Light emitting diode light therapeutic instruments
EP1457234B1 (en) Therapeutic light source and method
EP1871476B1 (en) Probe device for photobiomodulation of tissue lining a body cavity
WO2018090840A1 (en) Phototherapy device and method for use in metabolic disease
US20120123507A1 (en) Phototherapeutic Apparatus and Method
CN203525150U (en) Photon therapeutic instrument
RU2012110193A (en) DEVICE FOR ACTIN RADIATION IRRADIATION WITH DIFFERENT WAVE LENGTHS
CN105498096A (en) Optical wound therapy apparatus
CN104127958B (en) High-power phototherapy instrument with dynamically adjustable spectral energy
EP3402570B1 (en) Compact uvb light therapy device for treating dermal conditions
CN112043966A (en) LED facial mask appearance
KR20110118039A (en) Multi-directional light treatment apparatus
KR100848391B1 (en) Therapeutic light source and method using the same
CN205339869U (en) Optics wound therapeutic instrument
CN206577255U (en) A kind of Phototherapeutic device
CN112972906A (en) Multifunctional LED beauty and health lamp based on red, yellow and blue wavelength gain
CN214550672U (en) Portable multi-wavelength combined photon pulse physiotherapy instrument
CN203123358U (en) Semiconductor narrow-bandwidth breast disease therapeutic apparatus
RU96007U1 (en) DEVICE FOR RADIATING THE SURFACE OF A BODY WITH OPTICAL RADIATION AT BURNS
US20230149737A1 (en) Method and apparatus for treatment of pulmonary inflammation
KR20160071484A (en) Portable photodynamics therapeutic apparatus for using ALA
RU131973U1 (en) DEVICE FOR TREATMENT OF INFLAMMATORY DISEASES OF THE EXTERNAL EAR
KR20020088832A (en) Therapeutic light source and method using the same
US20170281965A1 (en) Assembly for photodynamic therapy
RU34382U1 (en) The device for therapeutic radiation "Magic beam"

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C53 Correction of patent of invention or patent application
CB03 Change of inventor or designer information

Inventor after: Wei Xunbin

Inventor after: Zhang Zhanxiang

Inventor before: Wei Xunbin

Inventor before: Zhang Zhanxiang

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100224

CF01 Termination of patent right due to non-payment of annual fee