CN101198366A - Method and apparatus for assisting patients in self administration of medication - Google Patents

Method and apparatus for assisting patients in self administration of medication Download PDF

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Publication number
CN101198366A
CN101198366A CNA2006800209985A CN200680020998A CN101198366A CN 101198366 A CN101198366 A CN 101198366A CN A2006800209985 A CNA2006800209985 A CN A2006800209985A CN 200680020998 A CN200680020998 A CN 200680020998A CN 101198366 A CN101198366 A CN 101198366A
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CN
China
Prior art keywords
pen
user
sound
injection pen
manual injection
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CNA2006800209985A
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Chinese (zh)
Inventor
R·格林
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Novo Nordisk AS
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Novo Nordisk AS
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Publication date
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Publication of CN101198366A publication Critical patent/CN101198366A/en
Pending legal-status Critical Current

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Abstract

The present invention relates to a manual injection pen (1) suitable for injecting a liquid medication via a non-electrical drive mechanism (33) . The injection pen (1) is provided with a plurality of sensors (50,70,200) that senses when a user is taking a specific action with the device. Further the injection pen (1) is provided with a sound generator (10) that generates a particular sound corresponding to the specific action taken by the user. In this way a characteristic sound signal can be provided for each specific action.

Description

The method and apparatus that is used for assisting patients in self administration of medication
Technical field
The present invention relates generally to treatment of diseases and the processing under the situation of patients in self administration of medication.Particularly, the present invention relates to a kind of self administration of medication simple and/or pleasant apparatus and method that become that make.The invention still further relates to the method for administration and to the method for patient's selling device and medicine.This be particularly suitable for must own injection drug patient use, but this and do not mean that and be restricted to injection device.
Background technology
Many kinds of diseases, for example diabetes and retardation of growth disease all need patients in self administration of medication usually.Under multiple situation, can not oral drugs.Although developed a lot of new route of administration, still need oneself these medicine of injection usually; Particularly, do one's utmost to carry out the pulmonary administration of insulin at present.Although have the device that is used for from injection or suction medicine at present, this device can not offer (incorporate) user close friend's feedback usually.Although some infusion pump comprises some warning systems, common discontinuous dosing apparatus also can't provide too many information in the mode of auditory feedback to user as injection pen.Usually, this injection pen includes only very simple mechanical snap formula (click) mechanism, and it can send " click is rattled away " sound to each increment of setting on the injection pen.
Summary of the invention
The present invention has improved the experience of patient aspect self administration of medication.In one embodiment, a kind of delivery device (as injection pen) has speaker or other can transmit the output device of audition, vision and/or tactile feedback to the patient.For example, therein among embodiment, when user touches this device at first,, perhaps when medicine is successfully exported from device, install and all can sound when user changes when being provided with.
Though the present invention can comprise the dynamo-electric delivery device that drives, also can comprise the low device of complexity that relies on pure mechanical part to carry medicine.
In some embodiments, the sound that is sent is can the person of being to use select from multiple sound, or downloads to this device from external source or computer network (as the Internet).
In embodiment, the present invention shows as a kind of delivery device, as injection pen therein.This injection pen has one or morely to be brought into use injection pen or even produces induced pick off when only touching injection pen at user.Described pick off can detect the exercises that user is taked.These actions comprise pick up injection pen, remove lid, attached together with pin, adjust dosage, with entry needle be inserted into user skin, injected dose, from the skin of user, take out pin, Jiang Gai and replace etc.Described device comprises electronics or the mechanical mechanism that speech chip or other can sounding.This device comprises that also the permission speech pattern downloads to the interface of device.
In embodiment, various speech patterns are loaded in this device in advance therein.Can select speech pattern based on the predetermined user of this device.For example, in being sold to child's injection pen, sound can make the sound of the popular child's cartoon of imitation or come from the sound in other popular kid's culture field.Therefore, of the present invention this is for specific patient group one of them of very useful many methods aspect the contained drug in selling device and/or selling device on the one hand.
In another embodiment, the present invention can provide a kind of mode of educating this device of user proper operation.For example, when the present invention was attached in the pen device, user can be come this pen of proper operation by synthetic sound instruction by instruction.Even when the patient is trained up to use this special device, the present invention also is being useful aspect the patient is reminded, for example make pin stop preset time under skin after the injection, their medicine of warning user is supplied with and is reduced, and perhaps reminds the user medicine to run low.
Description of drawings
Fig. 1 shows the exemplary of injection pen form of the present invention.
The specific embodiment
In this exemplary, the present invention is attached in the injection pen of a standard, as insulin injection pen.In U.S. Pat 6277098, US6302855, US6248090, US6004297, US6235004 discloses this injection pen among the US5626566, and the full content combination of these patents is in this application as a reference.
As shown in Figure 1, pen 1 has mechanical type dosing mechanism 11 and is used for discharging from pen the mechanical drive mechanism 33 of medicine, speaker 20 and user input part 30,40 that this pen comprises processor 10, links to each other with processor.Described user input part is used to control volume or other function, as gauge tap.
Described pen can also comprise various pick offs, produces the touch sensor 50 of response when touching at user.This touch sensor 50 can be aitiogenic any pick off when contacting with user, as pressure transducer, impedance variation pick off, resistance sensor-based system or other device that can detect when contacting.In addition, pen 1 also comprises a plurality of other pick offs that are used to detect various component movement.For example, injection pen 1 can be included in to remove to cover and produce induced lid at 100 o'clock and remove pick off 70.
In addition, also other pick off can be attached in the dosing mechanism and trigger these pick offs by setting dosage.These pick offs can be the pick offs that can the perception dosing mechanism moves that moves contact or rely on magnetic contact or other type.In addition, pen 1 also comprises the pin insert type pick off 200 that is connected with entry needle, thereby triggers this pick off when pin is inserted into skin surface.Usually, these pick offs all are connected with processor 10, so that when pick off is triggered, signal are sent to processor.Processor 10 is configured to produce sound or is connected, links or cooperate with sound-producing device such as sounding car (sound cart), and generation can drive the acoustical signal of speaker 20.
In this embodiment, all acoustical signals that are sent to speaker all are identical.In another embodiment, acoustical signal can change along with the difference of the pick off that is triggered.For example, remove and cover a kind of sound of 100 generations, the rotation dosing mechanism produces another kind of alternative sounds, sticks the needle into and then produces another sound in the skin.
Insert pick off 200 if pen 1 comprises pin, processor can be programmed to warn user with audible prompting when taking out pin from skin so.This time can be programmed to corresponding to after the injection pin being retained in time of needing in the skin (as 10 seconds, be generally 4-8 second).
In some embodiment, can also comprise that in conjunction with conveyer device of the present invention visual display or sense of touch show.Therefore, processor can show the choice menus that uses for user, and user can be selected option by user input part 30.
Some embodiment can also comprise and allows user that acoustical signal such as music etc. is downloaded to input part 300 in the pen 1.This input part is configured to allow the wireless communication of wired download or acceptance and external equipment, as PC or network (as the Internet).
In some embodiments, can adopt sound or patient's feedback system that the patient is reminded.For example, described device can be formed at this device a period of time and not be used to the patient and sound or send other audible signal or visual signal or tactile alert.For example, if do not use this device in the morning, the described device signal of will sounding.Other prompting does not for example carry normal daily dose can trigger sound yet.Can adopt multiple sound for different promptings.Therefore, the present invention can be used for improving patient's compliance, and therefore improves patient's treatment and achievement.
Embodiment 1
Can construct according to pen shown in Figure 1.Following in addition content also can be incorporated in this pen.This loaded in advance come from come true about the music in the popular child film of the toy fabricated.Hero in the film is a space toy that can send especial sound.Especially, this hero can send specific sound in laser by shooting the time, and can say unique motto when it is taken a risk.
In this embodiment, when removing from pen when covering, Pen Association sends and is similar to the laser sound of hero by shooting the time.When user is adjusted dosage, can send another kind and be similar to the sound that produces when watching film.When user sticks the needle into skin surface, then can from pen, send another sound.This sound can make user feel at ease, and tells him the part of pain finishes, and perhaps user is word or a sound " very brave " or that send other encouragement.When over and done with time enough, in the time of need extracting pin, Pen Association sends the motto of heroic toy.
Embodiment 2
According to embodiment 1, can make television advertising and show that the child uses this injection pen.Television advertising shows before and after can and playing in the playing process of the film of the sound that is provided for described pen.Because the target audience of film is the child, so the target of this advertisement equally also is the child.Suppose that spectators child are abundant, so just can calculate and watch this then advertisement and need potential child's quantity of this injection pen.Therefore, the present invention can provide a kind of utilization to watch that children television or film introduce the method for new elementary introduction to drug delivery technique to child and their parents, so that can help those to need the people of this technology.

Claims (5)

1. manual injection pen (1) by on-electric mechanism (33) injecting fluid medicine is characterized in that this pen (1) comprising:
A. one or more pick offs (50,70,200), it produces induction when the user use device is taken action, and
B. acoustical generator (10), specific sound is sent in its specific action of taking corresponding to user.
2. manual injection pen as claimed in claim 1 is characterized in that described acoustical generator (10) comprises processor (10).
3. manual injection pen as claimed in claim 1 or 2 is characterized in that described acoustical generator (10) can provide audible indication to the patient who uses this pen.
4. as claim 2 or 3 described manual injection pens, it is characterized in that described processor (10) receives the signal that comes from a plurality of pick offs (50,70,200), and sound or audible indication according to the combination of the signal that is received.
5. as each described manual injection pen in the claim 1 to 4, it is characterized in that this manual injection pen (1) comprises that also the permission audio files downloads to the input part in the acoustical generator (10).
CNA2006800209985A 2005-06-16 2006-06-15 Method and apparatus for assisting patients in self administration of medication Pending CN101198366A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69116705P 2005-06-16 2005-06-16
US60/691,167 2005-06-16
EP05109085.0 2005-09-30

Publications (1)

Publication Number Publication Date
CN101198366A true CN101198366A (en) 2008-06-11

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CNA2006800209985A Pending CN101198366A (en) 2005-06-16 2006-06-15 Method and apparatus for assisting patients in self administration of medication

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CN (1) CN101198366A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102497900A (en) * 2009-07-14 2012-06-13 赛诺菲-安万特德国有限公司 Drug delivery device
CN103458945A (en) * 2011-04-11 2013-12-18 诺沃—诺迪斯克有限公司 Injection device incorporating dose monitoring
CN103648552A (en) * 2011-07-15 2014-03-19 赛诺菲-安万特德国有限公司 Drug delivery device with electro-mechanic drive mechanism
CN106714873A (en) * 2014-09-15 2017-05-24 赛诺菲 Providing temperature-based feedback regarding delivery of a medicament
CN109843360A (en) * 2016-08-17 2019-06-04 尼莎·沙惠尼 Inject monitoring device and system
CN110036432A (en) * 2016-12-07 2019-07-19 艾斯曲尔医疗公司 Training device
CN112135649A (en) * 2018-05-18 2020-12-25 诺和诺德股份有限公司 Sensor assembly with identifier determination

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102497900B (en) * 2009-07-14 2014-05-21 赛诺菲-安万特德国有限公司 Drug delivery device
CN102497900A (en) * 2009-07-14 2012-06-13 赛诺菲-安万特德国有限公司 Drug delivery device
CN103458945A (en) * 2011-04-11 2013-12-18 诺沃—诺迪斯克有限公司 Injection device incorporating dose monitoring
CN103458945B (en) * 2011-04-11 2016-01-13 诺沃—诺迪斯克有限公司 In conjunction with the injection device of dose monitoring
US10758676B2 (en) 2011-07-15 2020-09-01 Sanofi-Aventis Deutschland Gmbh Drug delivery device with electro-mechanic drive mechanism
CN103648552A (en) * 2011-07-15 2014-03-19 赛诺菲-安万特德国有限公司 Drug delivery device with electro-mechanic drive mechanism
CN103648552B (en) * 2011-07-15 2016-08-31 赛诺菲-安万特德国有限公司 drug delivery device with electromechanical drive mechanism
CN106267472A (en) * 2011-07-15 2017-01-04 赛诺菲-安万特德国有限公司 Drug delivery device with electromechanical drive mechanism
US11660395B2 (en) 2011-07-15 2023-05-30 Sanofi-Aventis Deutschland Gmbh Drug delivery device with electro-mechanic drive mechanism
CN106267472B (en) * 2011-07-15 2019-08-30 赛诺菲-安万特德国有限公司 Drug delivery device with electromechanical driving mechanism
CN106714873A (en) * 2014-09-15 2017-05-24 赛诺菲 Providing temperature-based feedback regarding delivery of a medicament
CN109843360A (en) * 2016-08-17 2019-06-04 尼莎·沙惠尼 Inject monitoring device and system
US11752274B2 (en) 2016-08-17 2023-09-12 Sawhney Nisha Injection monitoring device and system
US11475795B2 (en) 2016-12-07 2022-10-18 Shl Medical Ag Training device
CN110036432A (en) * 2016-12-07 2019-07-19 艾斯曲尔医疗公司 Training device
CN112135649A (en) * 2018-05-18 2020-12-25 诺和诺德股份有限公司 Sensor assembly with identifier determination

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Open date: 20080611