CN101184981A - Single-hand operated syringe-like device that provides electronic chain of custody when securing a sample for analysis - Google Patents
Single-hand operated syringe-like device that provides electronic chain of custody when securing a sample for analysis Download PDFInfo
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- CN101184981A CN101184981A CNA2006800132521A CN200680013252A CN101184981A CN 101184981 A CN101184981 A CN 101184981A CN A2006800132521 A CNA2006800132521 A CN A2006800132521A CN 200680013252 A CN200680013252 A CN 200680013252A CN 101184981 A CN101184981 A CN 101184981A
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Abstract
A syringe-like device (hereinafter ''syringe'') that is operable by a single hand, wherein the syringe includes a plunger for ejecting and then retracting a fiber or filament used for the collection of solids, solids in suspensions and liquids, wherein the syringe includes a microchip embedded in the syringe housing, and wherein the microchip enables electronic chain of custody tracking of a sample from a point of origin through final analysis.
Description
Cross reference to related application
Presents requires to submit on April 21st, 2005, sequence number be 60/673745 and file number be 05-17 and submit on April 21st, 2005, sequence number be 60/673744 and file number be the temporary patent application of 05-18 as right of priority, and introduce whole themes of being contained in wherein as a reference.
Technical field
The present invention relates generally to be used for the syringe-like device of collection analysis with sample.More specifically, the invention provides the improved syringe-like device of the electronic chain of custody of the sample that makes it possible to when obtaining sample for analysis one-handed performance and make it possible to realize be collected.
Background technology
When explanation during correlation technique, consider that the sample that the present invention can lay various different materials is crucial.These materials comprise the chemicals of liquid or gas form, thus solid phase micro extraction (Solid Phase Microextraction SPME) is the applicable field of the present invention.But although SPME is generally relevant with extraction chemicals from liquid and steam, the present invention also can obtain sample from the suspending liquid of solid and solid.
SPME samples with chemical compound and the technology that concentrates is conventionally known to one of skill in the art to chromatography or other methods analyst as being used for.Usually, fiber is used to from sample extraction of analytes and transmits them be used for analyzing.Fiber generally is used for by separating or absorption is caught and the polymkeric substance of concentrating analysis or the fused silica or the metal fibre of absorbing agent are made by being coated with.The sample inlet port that fiber is shifted into chromatograph or spectrometer is used for desorption or extraction and analyzes.For convenience's sake, the fiber that is used for SPME generally is maintained in the syringe-like device.In the wall of the outward extending protective sleeve of syringe-like device, fiber is easy to protected and transmits.
Before explanation SPME technology, notice that the present invention is used to gather, concentrates, the syringe-like device of transmission and injected sample.Though at its shell stored liquid, shell of the present invention is built as and seems syringe-like syringe-like device unlike the syringe of reality, this instrument used for injection has handle, piston and is actually the nadel body of the sheath that is used for above-mentioned fiber.Therefore, the term that uses in presents and the claim " syringe " is the syringe-like device that will more prove absolutely below, should not be mistaken for actual syringe.
One of the shortcoming that is used for the existing syringe of SPME is general two manual manipulations of needs.For example, after taking sample, first stack shell (shaft) that holds syringe, second hand-lifting goes out piston so that fiber is moved in the syringe simultaneously.Therefore, obtain two hands of process need of sample.Therefore, aspect the SPME syringe, can be advantage than the prior art state thereby the syringe that can only make second hand freely be used for other task with a manual manipulation is provided.
Understandably, SPME is not that must consider of the present invention only has application.Obviously, another aspect of the present invention can use the syringe acquisition of the solid from solid and suspending liquid sample equally.For example, different with the fiber that is used for from liquids and gases collection sample, solid can be collected on the filament.Filament of the present invention is designed to have cavity, hole or other similar characteristics of making it possible on filament or collecting solid in the filament.As will be revealed, the present invention also is provided for collecting the device of the solid in the suspending liquid.
Also need carefully to follow the tracks of sample by being transferred to final analysis from starting point.Provide to have fiber or filament and comprise and be used for electronics to follow the tracks of the said syringe of device of the Chain of Custody of sample can be another advantage than the prior art state.
Summary of the invention
The present invention be a kind of can be by the syringe-like device (hereinafter referred to as " syringe ") of one-handed performance, wherein, syringe comprises to be used for discharging returns solid and the fiber of liquid or the piston of filament that is used to collect solid, suspending liquid then, syringe comprises the microchip that is embedded in the syringe shell, and microchip makes it possible to provide the electronic chain of custody of following the tracks of sample from starting point until final analysis.
Read following detailed description in conjunction with the accompanying drawings, these and other objects of the present invention, feature, advantage and substituting aspect will it will be apparent to those skilled in the art.
Description of drawings
Fig. 1 is the perspective view according to the syringe of the assembling of principle instruction of the present invention.
Fig. 2 is the wire frame skeleton view according to the syringe of the assembling of principle instruction of the present invention.
Fig. 3 is the exploded wireframe perspective view of the parts that use in syringe illustrated in figures 1 and 2.
Fig. 4 provides the diagrammatic sketch that is designed to receive from syringe of the present invention receiving port on the analyzing device of sample.
The example that Fig. 5 provides the interior ID circuit of a part of the handle of syringe to place.
Fig. 6 provides the circuit diagram of circuit of visit of the storer of the ID circuit that is arranged in the syringe body.
Fig. 7 provides the circuit diagram of circuit of accessed record instrument of the storer of ID circuit.
Fig. 8 is the diagrammatic sketch of the evaporation process of the solid in the suspending liquid on the twisted filament.
Fig. 9 is the diagrammatic sketch of three rhizoids (wire) of whipper (whisk) that is formed for obtaining the sample of the solid in solid and the suspending liquid.
Embodiment
Referring now to accompanying drawing, in these accompanying drawings, give each element Reference numeral of the present invention and the present invention is discussed so that those skilled in the art can implement and use the present invention.Should be appreciated that following explanation only exemplarily illustrates principle of the present invention, and should not be regarded as the scope of following claim is narrowed down.
Fig. 1 be provided for can be only with the perspective view of the first embodiment of the present invention of a manual syringe 10.Visible in the figure parts comprise shell or handle 12, thumb actuator (actuator) 14, end cap (ground cap) 26 and are used for filament or the shell or the protective sleeve 28 of fiber (below be referred to as " fiber ").
Fig. 2 provides the wire frame skeleton view of the first embodiment of the present invention shown in Figure 1.Visible in the figure parts comprise shell or handle 12, thumb actuator 14, cam mechanism 16, piston 18, spring 20, be suitable for filament or fiber 22, identification (ID) circuit 24, end cap 26, shell that is used for fiber or the protective sleeve 28 that solid from liquid, steam, solid or suspending liquid obtains sample to be analyzed, the electrode 30 that is arranged on ID circuit 24 downsides.
Fig. 3 is with all parts of the syringe 10 of exploded view presentation graphs 1, and wherein, when extraction, transmission and transimiison analysis were used sample, syringe can one-handed performance.As mentioned above, these parts comprise shell or handle 12, thumb actuator 14, cam mechanism 16, piston 18, spring 20, fiber 22, identification (ID) circuit 24, end cap 26 and are used for the shell or the protective sleeve 28 of fiber.Fiber clamp 32 is provided to fiber is fixed in the handle 12.Notice that two other parts are sightless, but still are contained in the parts that illustrate in this view.These parts are arranged on two strip of paper used for sealings in the end cap 26.
It is simple relatively only using the operation of syringe 10 of first embodiment of a hand.In first embodiment, the user holds handle 12 with all fingers of a hand, makes thumb be placed on the thumb actuator 14.Scheme as an alternative, the user can hold handle 12 between the forefinger of a hand and middle finger.Thumb is placed in the top of thumb actuator 14 then, makes it be ready to operate in arbitrary embodiment.
The user can freely use and not take the hand of syringe 10 to carry out other task.These tasks comprise such as fixed sample container when obtaining sample, prepare the device that analytical equipment is used for the sample introducing and takes other.Therefore, the user can freely use empty hand to finish any other task obviously, and generally will freely carry out otherwise need be by the task of another person's execution.Therefore, the present invention not only makes the user can carry out the task more than when taking sample, and makes it possible to take sample under the situation of having only a people to execute the task.
Note, for the sake of clarity, be meant the solid in liquid, solid and the suspending liquid of any material of available fiber sampling of the present invention below the term " sample ".
Being described in more detail of operation of syringe 10 described for first embodiment here.Syringe 10 of the present invention comprises camming, locks fiber 22 in the position of stretching out when activating for the first time with box lunch and discharges when activating for the second time and return fiber.Need spring 20 so that camming works as described above.
Be that the spring 20 that uses in this first embodiment can be replaced by any suitable spring-like device that provides cam mechanism 16 to play a role needed tension force for important understanding of the present invention.Similarly; because spring 20 and cam mechanism 16 are used as and make fiber 22 can discharge and be retracted into the system in the protective sleeve 28 from protective sleeve 28, so this system can be one aspect of the present invention by being used to provide any equality unit replacement of this fiber discharge and retraction.
Continue first embodiment, when syringe 10 was ready to use, fiber 22 was loaded in the handle 12 and by fiber clamp 32 and is fixed.For example, fiber clamp 32 can be little nut.Fiber clamp 32 prevents that with strip of paper used for sealing any chemicals from entering in the handle 12.After being used to fixed sample, fiber clamp 32 also makes it possible to remove and change fiber 22.But, can imagine that syringe 10 will be enough cheap, make that it can be a disposable.But it is contemplated that if desired, fiber 22 can be replaced and syringe 10 can be reused.
When the user was ready to syringe 10 samplings, the user must lock fiber 22 in the drain position, makes sample to be set on the fiber by absorption, absorption, static charge etc.The user uses finger (being generally thumb) on thumb actuator 14.Thumb actuator 14 slips in the handle 12, arrives camming up to it and prevents that fiber 22 is retracted into the point in the protective sleeve 28.This moment in this process, the user needn't keep finger to be on the thumb actuator 14 in order to make fiber 22 keep stretching out from protective sleeve 28.The user makes fiber 22 remain on then and well known to a person skilled in the art the reasonable time amount in the sample.
In first embodiment of syringe 10, for being moved to, cam mechanism 16 allow fiber 22 to be retracted into different position in its protective sleeve 28, and the user pushes thumb actuator 14 once more.Syringe 10 is shifted into storage then or is brought to the chemical analysis station, and at this chemical analysis station, the sample that is absorbed by fiber 22 is retrieved also analyzed.
Should be noted that the camming that illustrates can be modified to operation in a different manner in first embodiment.For example, cam mechanism also can activated by thumb, but comprises the tripper (locking release) that can touch in handle 12 outsides.Therefore, discharge the fiber 22 that stretches out and comprise mobile protrusion (tab) or other releasing means that is arranged on handle 12 sides.
Note, in case when fiber 22 stretches out from its protective sleeve 28 outside, syringe 10 can also be appended on the container of maintenance sample.Therefore, syringe 10 makes it possible to carry out " without hand " operation when sample is absorbed.But this is optional aspect of the present invention, is not the necessary condition of first embodiment.
In case sample is obtained, fiber 22 just is retracted in the protective sleeve 28.Protective sleeve 28 is not only protected the sample that is absorbed by fiber 22, also avoids user or on the scene other people to touch chemicals in the sample.The user is release cam mechanism 16 and fiber 22 is retracted in the protective sleeve 28 by for the second time activating thumb actuator 14.
Above-mentioned first embodiment has illustrated the camming in the single desired location of fiber 22 being locked its protective sleeve 28 outsides when sample is obtained.But, in an alternative embodiment, can imagine that camming comprises the device that makes that fiber 22 can be exposed with ever-increasing length outside protective sleeve 28.Therefore can imagine, in an alternate embodiment, can be exposed to the maximum length of discharging up to fiber by when repeatedly activating thumb actuator 14, using predetermined increment size exposed fibers 22.
In another alternate embodiment, it is contemplated that fiber 22 can be exposed in the mode of non-increment, and be exposed to the non-predetermined length of any hope, up to the maximum length of fiber.It is contemplated that therefore fiber 22 is discharged from thumb actuator 14 and is pushed into the direct proportional length of length in the handle 12.
In case sample is obtained, sample just is safely moved to for example analytical equipment or memory device.The example of the type of the analysis that can be performed comprises mass spectrophotometry, ion mobility spectroscopic assay, gas chromatographic analysis, liquid-phase chromatographic analysis, Flow Injection Analysis (flow injectionanalysis) etc.Importantly analytical equipment comprises the injection port that is used to receive syringe 10 for purposes of the invention.
Fig. 4 provides the diagrammatic sketch of the analytical equipment 40 that is designed to receive syringe 10.Analytical equipment itself is not a key element of the present invention.But injection port 42 shown in Figure 4 is correlated with, and is used for the circuit shown in Figure 7 of communicating by letter with ID circuit 24 because it comprises.As long as satisfy two criterions, receiving port 42 just can be any desirable shape.The first, injection port 42 must have the hole 46 that is used to receive protective sleeve 28.The second, injection port 42 must provide the surface that at least two electrodes 44 can be set thereon, and wherein, described at least two electrodes must electrically contact with two electrodes 30 of syringe 10.Outside these two requirements, analytical equipment 40 is only limited by the demand of himself.
Scheme as an alternative, syringe 10 can couple with receiving port 42 by twisting handle 12, thus by in receiving port, be provided with complementary locking channel (channel) with syringe mechanical caging to receiving port.In case making fiber be discharged in the analytical equipment 40, this alternate embodiment just can transmit sample without hand.
Another importance of this first embodiment of the present invention is that the microchip that will have storer embeds in the syringe 10.Microchip is used to discern uniquely the sample that is absorbed by fiber 22.Therefore, following microchip and storer will be collectively referred to as identification (ID) circuit 24.The definite layout of ID circuit 24 in this first embodiment discharged near its fiber and return end, make it can be at an easy rate with can electrically contact from ID circuit reading of data or to the device that the ID circuit writes data.Fig. 5 provides a kind of example of possible position, and wherein, ID circuit 24 can be set in the part of handle 12 of syringe 10.More specifically, being arranged on ID circuit 24 on himself circuit board can be arranged on below the bead 48 on the handle 12.But it should be noted that is not influencing in fact under the situation of operation of the present invention, and the layout of ID circuit 24 can be changed.Important just ID circuit 24 is positioned as and makes it to communicate by letter with receiving port 42 interior electrically contacting.
In this first embodiment, ID circuit 24 is any number storage module and the I/O circuit that make it possible to store and read the data of the electronic chain of custody that can keep sample.Storer is preferably non-volatile, even make that being removed the back data at electric power also remains in the storer safely.The use of nonvolatile memory makes does not need to be used for preserving at storer the battery of data in the syringe 10.
In alternate embodiment of the present invention, it is contemplated that ID circuit 24 is also only comprised memory module by further the simplification.Therefore, any register instrument must be provided for the device with memory communication.
When the storer of considering to be used for the first embodiment of the present invention essential, notice that the data that are stored in wherein can not be wiped free of after being stored.Therefore, though new information can be added in the storer, old information is retained always.Storer also can be read at any time not revising under the data conditions.
In an alternative embodiment, it is contemplated that reusable syringe comprises the ID circuit 24 of the storer that use can be wiped fully.Importantly, memory erase can not be optionally, avoids the suspection about the integrality of electronic chain of custody thus.
In another alternate embodiment, it is contemplated that reusable instrument used for injection is useful on the removable fiber of collection sample and new ID circuit 24.Fiber 22 and ID circuit 24 are individual units of guaranteeing the integrality of electronic chain of custody again.
Another importance of the storer of first embodiment is that it has stored the unique code of ID circuit 24 therein.By giving each ID circuit 24 unique code, because two ID circuit can not have identical code, so electronic chain of custody is guaranteed again.Therefore, even syringe is reusable, still needing provides new unique code for the storer that uses in ID circuit 24.
Can store data by using suitable physics and being electrically connected to fetch in the storer that is implemented in ID circuit 24.Be used for to the nonvolatile memory stores data and therefrom the system and method for reading of data be well known to a person skilled in the art, therefore be used to realize that the means of these tasks are not particular importances for the present invention.To the present invention importantly, be applied to electronic chain of custody task memory stores and fetch (retrieval) The Application of Technology.
Physical connection was carried out in first embodiment requirement between syringe 10 and register instrument before data can be stored in the ID circuit 24 a reason is that the data that this step prevents to be stored in are wherein carried out undesirable altering.Therefore, it is inappropriate the storer storage data that the wireless device such as radio frequency (RF) or infrared (IR) device is used at ID circuit 24 being set.But the RF or the IR device that are used for reading of data are admissible, and should be regarded as in the scope of alternate embodiment of the present invention.
Be stored in the nonvolatile memory of ID circuit 24 can be selected from and generally be considered to this purpose Useful Information with the data that produce electronic chain of custody.For example, this information can comprise but should not be regarded as being limited to sampling time and date, obtain sample the position, carry out sampling, storage or the operator's that analyzes cognizance code and be used for unique cognizance code of register instrument.
Be used to ID circuit 24 storage data and therefrom the register instrument of reading of data can be portable or static device.Therefore, register instrument can pass through powered battery, or directly by the current practice from wall socket.
Visit for register instrument can be provided by any interface easily.For example, computing machine can connect by USB interface, live wire (Firewire) or any other wired access protocal or hardware provides to register instrument and from there to the visit of ID circuit 24.As mentioned above, in substituting embodiment, wireless accessing device also can be configured to read the data that are stored in the ID circuit 24.In this case, ID circuit 24 also must comprise and be used to transmit the device that is stored in data wherein.
Register instrument also can comprise display and keyboard, makes that it needn't be accessed by computing machine, makes it become real autonomous device thus.But, provide visit the most possible size and sophistication that reduces register instrument by computing machine, and avoid register instrument self to need keyboard and display thus.
The specialized version of register instrument is designated as the analyser register instrument.The analyser register instrument can be designed to provide the interface with specific analyser.In first embodiment, the analyser register instrument is configured to make that it is programmed with whole particular demands of the particular analysis instrument of operating with it.
Fig. 6 provides the circuit diagram of a possibility embodiment of the circuit that can be used for visiting the ID circuit 24 on the syringe 10.This circuit illustrates first and is electrically connected 50 and second electrical connection 52, diode 54, resistor 56, capacitor 58 and Nonvolatile memory devices 60.
In order to replenish the circuit of Fig. 6, Fig. 7 provides the circuit diagram of a possibility embodiment of the circuit that can be used in the register instrument, and this register instrument and ID circuit 24 couple to obtain visit and to send data or fetch data.Fig. 7 illustrates first and is electrically connected 70, second electrical connection 72, I/O driver chip 74, diode 76 and microcontroller 78.Microcontroller 78 will comprise the visit for the exterior I that is used for communicating by letter with outer computer/O port via circuit 80, perhaps, if register instrument is as autonomous device, for the visit of innernal CPU.
Though ID circuit 24 is used to provide the Chain of Custody of the sample that is absorbed by fiber 22, the ID circuit also can be used in other device.For example, general syringe, be used for collecting the filtrator of sample and being used for fixing plug (plug) sampling device of the sample of solid material from air or other gaseous environment.
Of the present invention several aspects that further explanation is provided are from fiber 22 beginnings of the filament that forms the solid that is used for collecting liquid, solid or suspending liquid.Solid in the collection suspending liquid shown in Figure 8.Fig. 8 illustrates the twisted wire 90 of the drop 92 with solid in the suspending liquid disposed thereon.Liquid in the suspending liquid is evaporated shown in four diagrammatic sketch that liquid in twisted wire 90 and the suspending liquid fades away, on remaining on twisted wire all be solid 94 in the suspending liquid till.This solid twisted wire 90 the silk between and separate out on every side.Twisted wire 90 (it is a fiber 22) can be retracted in the protective sleeve 28 now.
By using whipper shown in Figure 9 100 to illustrate to be used for another system of the solid of collecting liquid, solid and suspending liquid.Fig. 9 illustrates three rhizoids 102 that are configured to whipper 104 shapes.The all alternative design shown in Figure 9 of shape of any suitable whipper shape of the function that realization will illustrate.Importantly, can by whipper 104 is placed in the liquid, withdrawal whipper and as the liquid among Fig. 8 is done, evaporate liquid in the sample and obtain solid in the suspending liquid.
As last aspect of the present invention, can produce suitable whipper 104 by using following process.Three nitinol wires at one end are welded together.It is in 0.006 inch the stainless-steel tube that three free ends of silk are inserted into internal diameter.Metal spacer is inserted into three then and follows between the silk silk is separated and formation whipper 104.Silk and pipe were placed in 500 ℃ the stove 5 minutes then.Can remove sept now, and the memory effect that causes remains desirable shape with whipper 104 now on three rhizoids.Three rhizoids are removed from pipe now and couple with the stilt that is inserted in the syringe 10.
Should be appreciated that above-mentioned configuration only exemplarily illustrates the application of principle of the present invention.Under the situation that does not deviate from the spirit and scope of the present invention, those skilled in the art can design a large amount of change schemes and alternate configuration.Appended claim purpose is to cover these change schemes and configuration.
Claims (43)
1. the syringe of the sample of a material that is suitable for obtaining wanting analyzed, wherein, syringe only needs one-handed performance, and described syringe comprises:
Be suitable for from wanting analyzed material to collect the fiber of sample;
Be used to protect the protective sleeve of fiber, wherein, fiber can extract and return the inside from protective sleeve;
Be used to activate the piston that is used for discharging and returning the device of fiber from protective sleeve; With
Thumb actuator, this thumb actuator and piston couple, and promote piston when causing device to hold handle and to promote thumb when finger thus, discharge and retraction means with one-handed performance thus.
2. syringe as claimed in claim 1, wherein, the device that is used to discharge and return fiber also comprises:
Be arranged on and be used in the handle fiber being locked drain position and being used to discharge the cam mechanism that fiber makes that it can be return; With
Be used to cam mechanism that the tensioner of tension force is provided.
3. syringe as claimed in claim 2; wherein; cam mechanism also comprises latched position; wherein; cam mechanism is remained under the tension force to discharge fiber from protective sleeve by tensioner when thumb actuator is pushed for the first time; and thumb actuator can be released when fiber remains in the drain position.
4. syringe as claimed in claim 3, wherein, cam mechanism also comprises unlocked position, and wherein, cam mechanism is released under tension force when thumb actuator is pushed for the second time, makes fiber to be retracted in the protective sleeve thus.
5. syringe as claimed in claim 3, wherein, cam mechanism also comprises unlocked position, and wherein, cam mechanism is released under tension force when the releasing means of handle side activated, and makes fiber to be retracted in the protective sleeve thus.
6. syringe as claimed in claim 3, wherein, cam mechanism also comprises and is used to make fiber can respond repeatedly activating of thumb actuator and is discharged from the device of discharging length up to the maximum that reaches fiber in the mode of increment.
7. syringe as claimed in claim 3, wherein, cam mechanism also comprises and is used to make that fiber can be discharged to the device that is pushed into the direct proportional non-increment size of length in the handle with thumb actuator.
8. syringe as claimed in claim 1, wherein, syringe also comprises identification disposed thereon (ID) circuit, and wherein, the ID circuit makes it possible to provide the electronic chain of custody of the sample that is obtained by fiber.
9. syringe as claimed in claim 8, wherein, syringe also comprises at least two of being used to make it possible to the ID circuit communication on its outer surface and is electrically connected.
10. syringe as claimed in claim 9, wherein, the ID circuit also comprises at least one memory module, and wherein, memory module is non-volatile, keeps data to make it possible to being removed the back at electric power from the ID circuit thus.
11. syringe as claimed in claim 10, wherein, described at least one memory module also comprises the storer that can only be written into and read but can not be wiped free of, and guarantees the integrality of the electronic chain of custody of sample thus.
12. syringe as claimed in claim 10, wherein, described at least one memory module also comprises the storer that can be written into, read with bulk erase, if guarantee that thus described at least one memory module is re-used, the integrality of the electronic chain of custody of sample is guaranteed.
13. the system as claimed in claim 1, wherein, system also comprises register instrument, and wherein, register instrument can write data and from ID circuit sense data to the ID circuit.
14. system as claimed in claim 13, wherein, register instrument is the autonomous device of interface with the user of self, and the information that makes can be written into the ID circuit according to the order of input register instrument and read from the ID circuit.
15. system as claimed in claim 13, wherein, the register instrument and second device couple, and wherein, second device provides interface, and the information that makes can be written into the ID circuit according to the order of input second device and read from the ID circuit.
16. system as claimed in claim 13, wherein, register instrument can be powered by battery or external power source.
17. system as claimed in claim 13, wherein, system also comprises and is used to mechanical hook-up that syringe and register instrument machinery are coupled, makes it possible to thus transmit sample to register instrument in without the hand process.
18. syringe as claimed in claim 1, wherein, syringe also comprises radio communication device, and wherein, radio communication device can only be used to transmit data from the ID circuit.
19. the system of syringe as claimed in claim 13 and register instrument, wherein, register instrument also comprises the analyser register instrument, wherein, analyser register instrument and analyser couple, and the analyser register instrument is become to operate with specific analyser by specialized designs, with the operation of enhanced system thus.
20. the system of syringe as claimed in claim 13 and register instrument, wherein, register instrument also comprises:
With the 1st electrically contacting that the output of input of the data of I/O driver and the 1st diode couples;
With the 2nd electrically contacting that the input of input of the ground connection of I/O driver and the 1st diode couples; With
With go into connector and data in data and go out the microcontroller that connector I/O driver couples, and microcontroller also comprises and is used for and innernal CPU or external communication ports communicating devices.
21. syringe as claimed in claim 2 wherein, is used to cam mechanism to provide the tensioner of tension force also to comprise spring.
22. a syringe that only needs a manual manipulation also to obtain sample thus by use obtains the method for the sample of material that will be analyzed, said method comprising the steps of:
(1) provides and have the shell, the protective sleeve that are provided with fiber therein, be used to activate and be used for discharging and return the piston of device of fiber and the thumb actuator that couples with piston from protective sleeve;
(2) hold the shell of syringe with the finger of first hand;
(3) thumb with first hand is placed on the thumb actuator; With
(4) promote thumb actuator only to use first hand actuating cam mechanism thus with thumb for the first time.
23. method as claimed in claim 22, wherein, this method is further comprising the steps of:
(1) use the cam mechanism be arranged in the handle to be used for fiber locked drain position and be used to discharge fiber making it to be return; With
(2) use spring to think that cam mechanism provides tension force.
24. method as claimed in claim 23, wherein, this method is further comprising the steps of: for the second time promote thumb actuator with thumb, thus release cam mechanism and cause fiber to be retracted in the protective sleeve.
25. method as claimed in claim 23, wherein, this method is further comprising the steps of:
(1) provides first latched position for cam mechanism; With
(2) when being pushed for the first time, thumb actuator use spring that cam mechanism is remained under the tension force, to discharge fiber from protective sleeve; With
(3) when discharging thumb actuator, fiber is remained on drain position.
26. method as claimed in claim 23, wherein, this method is further comprising the steps of:
(1) provides unlocked position for cam mechanism; With
(2) when thumb actuator is pushed for the second time by cam mechanism is moved to unlocked position and the tension force of retracting spring; With
(3) fiber is retracted in the protective sleeve.
27. method as claimed in claim 26, wherein, this method is further comprising the steps of:
(1) is provided for responding repeatedly activating and the device of increment ground discharge fiber of thumb actuator; With
(2) repeatedly activate thumb actuator, discharge length up to the maximum that reaches fiber.
28. method as claimed in claim 26, wherein, this method is further comprising the steps of:
(1) is provided for the device that fiber is discharged on non-increment ground;
(2) activate thumb actuator, discharge fiber and thumb actuator thus and be pushed into the interior direct proportional length of length of shell.
29. method as claimed in claim 22, wherein, this method is further comprising the steps of:
(1) identification (ID) circuit is set in syringe; With
(2) recorded information in the ID circuit, the electronic chain of custody that makes it possible to follow the tracks of the sample that obtains by fiber thus.
30. method as claimed in claim 29, wherein, this method is further comprising the steps of:
(1) at least two electrical connections of ID circuit is set on the outside surface of shell; With
(2) be connected electrically in canned data on the ID circuit by described at least two.
31. method as claimed in claim 30, wherein, this method is further comprising the steps of: at least one non-volatile memory module is set in the ID circuit, and wherein, memory module is removed the back at electric power and keeps the information that is stored in wherein from the ID circuit.
32. method as claimed in claim 31, wherein, this method is further comprising the steps of:
(1) make it possible to from the unlimited number of times of described at least one non-volatile memory module read;
(2) make it possible to write, up to reaching memory capacity to described at least one non-volatile memory module; With
(3) prevent to wipe any data, guarantee the integrality of the electronic chain of custody of sample thus from described at least one non-volatile memory module.
33. method as claimed in claim 32, wherein, this method is further comprising the steps of:
(1) make it possible to from the unlimited number of times of described at least one non-volatile memory module read;
(2) make it possible to write, up to reaching memory capacity to described at least one non-volatile memory module; With
(3) if memory module will be re-used, then make it possible to wipe all data fully from described at least one non-volatile memory module, guarantee the integrality of the electronic chain of custody of sample thus.
34. method as claimed in claim 22, wherein, this method is further comprising the steps of: provide to the ID circuit to write and from the register instrument of ID circuit sense data.
35. method as claimed in claim 34, wherein, this method is further comprising the steps of: provide independently register instrument, wherein, register instrument provides the user's of himself interface, and the information that makes can be written into the ID circuit according to the order of input register instrument and read from the ID circuit.
36. method as claimed in claim 34, wherein, this method is further comprising the steps of:
(1) register instrument and second device are coupled; With
(2) operate second device as the interface of register instrument, wherein, information can be written into the ID circuit according to the order of input second device and read from the ID circuit.
37. method as claimed in claim 36, wherein, this method is further comprising the steps of:
(1) when register instrument is operated away from external power source, register instrument is powered with battery; With
(2) but when the external power source time spent, register instrument is powered with external power source.
38. method as claimed in claim 36, wherein, this method is further comprising the steps of: be provided for syringe machinery is couple to the mechanical hook-up of register instrument, make it possible to thus transmit sample to register instrument.
39. method as claimed in claim 29, wherein, this method is further comprising the steps of:
(1) provides radio communication device; With
(2) only transmit data from circuit I D.
40. method as claimed in claim 34, wherein, this method is further comprising the steps of:
(1) provides the analyser register instrument; With
(2) analyser register instrument and chemical analyzer are coupled, wherein, the analyser register instrument is become to operate with the operation of enhanced system thus with specific chemical analyzer by specialized designs.
41. the syringe of the sample of a material that is suitable for obtaining wanting analyzed, wherein, syringe only needs one-handed performance, and described syringe comprises:
Be suitable for from wanting analyzed material to collect the fiber of sample;
Be used to protect the protective sleeve of fiber, wherein, fiber can be extracted out and return the inside from protective sleeve;
Be used to activate the piston that is used for discharging and returning the device of fiber from protective sleeve;
Thumb actuator, this thumb actuator and piston couple, and promote piston when causing device to hold handle and to promote thumb when finger thus, discharge and retraction means with one-handed performance thus; With
Identification disposed thereon (ID) circuit, wherein, the ID circuit makes it possible to provide the electronic chain of custody of the sample that is obtained by fiber.
42. syringe as claimed in claim 41, wherein, fiber is selected from silk, silk that weaves that comprises SPME fiber, distortion and the group of fibers that forms the silk of whipper.
43. the syringe of the sample of a material that is suitable for obtaining wanting analyzed, wherein, syringe only needs one-handed performance, and described syringe comprises:
Be suitable for from wanting analyzed material to collect the fiber of sample;
Be used to protect the protective sleeve of fiber, wherein, fiber can be extracted out and return the inside from protective sleeve;
Be used for discharging the piston of fiber from protective sleeve;
Be arranged on and be used in the handle fiber being locked drain position and being used to discharge the cam mechanism that fiber makes that it can be return;
The spring that is used for providing tension force in the handle to cam mechanism; With
Thumb actuator, this thumb actuator and piston couple, and promote piston when causing device to hold handle and to promote thumb when finger thus, use the one-handed performance cam mechanism thus.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67374405P | 2005-04-21 | 2005-04-21 | |
| US60/673,745 | 2005-04-21 | ||
| US60/673,744 | 2005-04-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101184981A true CN101184981A (en) | 2008-05-21 |
Family
ID=39449499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006800132521A Pending CN101184981A (en) | 2005-04-21 | 2006-04-21 | Single-hand operated syringe-like device that provides electronic chain of custody when securing a sample for analysis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101184981A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107530504A (en) * | 2015-03-31 | 2018-01-02 | 南方依诺维绅兹有限公司 | For making needle device depart from sheath and the equipment for reentrying sheath |
| CN110234973A (en) * | 2017-01-31 | 2019-09-13 | 珀金埃尔默健康科学有限公司 | Coil wire type sampler |
-
2006
- 2006-04-21 CN CNA2006800132521A patent/CN101184981A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107530504A (en) * | 2015-03-31 | 2018-01-02 | 南方依诺维绅兹有限公司 | For making needle device depart from sheath and the equipment for reentrying sheath |
| US10722659B2 (en) | 2015-03-31 | 2020-07-28 | Southern Innovationz Limited | Apparatus for unsheathing and resheathing a needle device |
| CN110234973A (en) * | 2017-01-31 | 2019-09-13 | 珀金埃尔默健康科学有限公司 | Coil wire type sampler |
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Open date: 20080521 |