CN101175405A - Anti-bacterial composition and anti-bacterial material - Google Patents
Anti-bacterial composition and anti-bacterial material Download PDFInfo
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- CN101175405A CN101175405A CNA2006800171526A CN200680017152A CN101175405A CN 101175405 A CN101175405 A CN 101175405A CN A2006800171526 A CNA2006800171526 A CN A2006800171526A CN 200680017152 A CN200680017152 A CN 200680017152A CN 101175405 A CN101175405 A CN 101175405A
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- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/12—Iodine, e.g. iodophors; Compounds thereof
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Abstract
The aim of the present invention is to provide means for effectively utilizing iodine in an anti-bacterial material. An anti-bacterial composition comprising (A) an iodine-containing compound, (B) an iodine-containing oxidizing agent and (C) an acid compound, the iodine-containing compound (A) and the iodine-containing oxidizing agent (B) being contained at a ratio by mass: (B)/(A) = 1 to 1000; and an anti-bacterial material comprising a solid substrate and (A) an iodine-containing compound, (B) an iodine-containing oxidizing agent and (C) an acid compound retained within or on the surface of the solid substrate, the iodine-containing compound (A) and the iodine-containing oxidizing agent (B) being contained at a ratio by mass: (B)/(A) = 1 to 1000.
Description
Technical field
The present invention relates to anti-bacterial composition and anti-bacterial material.In detail, the present invention relates to contain the anti-bacterial composition and the anti-bacterial material of iodine.
Background technology
In our living space, exist microorganisms such as various bacteriums or mould.These microorganisms become the reason of food spoilage, stench generation, bring offending sensation to us.In addition, for human body, become the reason that causes the various diseases headed by the food poisoning.For life wholesomely, suppress these microbial reproductions or remove these microorganisms extremely important.
Viewpoint is set out thus, has proposed various schemes for the living space that cleaning is provided in the past.As one, iodine receives publicity.This is because iodine has the broad-spectrum antiseptic spectrum, and very high to the safety of human body, has excellent antibiotic property.
But, even if iodine also is easy to distillation at normal temperatures.Therefore when iodine directly is used for the purposes of antibiotic or deodorizing with simple substance, has the problem that can't obtain abundant effect owing to the distillation of iodine.
In order to remedy this shortcoming, to reduce the volatility of iodine etc., various iodine attached (iodophor) (for example with reference to Japanese Patent Publication 60-19762 communique, No. 2739922 specification of United States Patent (USP), No. 3028300 specification of United States Patent (USP) and Japanese kokai publication sho 51-88625 communique) have been proposed.As the attached object lesson of iodine, in Japanese Patent Publication 60-19762 communique, disclose as the shitosan of carrier and the complex of iodine.The complex (below be also referred to as " betadin ") of polyvinylpyrrolidone (PVP) as carrier and iodine is disclosed in No. 2739922 specification of United States Patent (USP) and No. 3028300 specification of United States Patent (USP) in addition.And, in Japanese kokai publication sho 51-88625 communique, disclose iodine atom bag and be connected on the iodo-cyclodextrin bag that forms in the cyclodextrin and connect compound (below be also referred to as " CDI ").
In addition, also attempt by the attached base material that remains in of these iodine is given the base material antibiotic property and made anti-bacterial material.For example, in TOHKEMY 2001-89974 communique, disclose povidone iodine and remained in the fiber base material that fiber surface forms with the regulation polymer.In addition, sterilization, the corrosion-proof packing paper that beta-schardinger dextrin-inclusion compound that iodine is set forms is disclosed in Japanese kokai publication sho 51-100892 communique.
The technology of being put down in writing as TOHKEMY 2001-89974 communique and Japanese kokai publication sho 51-100892 communique, if the form attached with iodine remains in fiber base material with iodine, then compare with use the situation of iodine with simple substance, can suppress iodine distillation, can improve the continuation of effects such as antibiotic or deodorizing.
In addition, disclose solid iodophor composition (preparation) in Japanese kokai publication sho 63-225308 communique and the Japanese kokai publication hei 2-110 communique, it contains iodophor, iodide, oxidant and powder acid and contains the powder alkali with the character that foams with the powder acid reaction as required.By these technology, can provide and make simple and stable solid iodophor composition (preparation).
Summary of the invention
But, be held in the anti-bacterial material (for example sheet anti-bacterial material) that base material forms in that iodine is attached, still have a certain amount of iodine to distil from substrate surface, the iodine concentration that is held in base material successively decreases.Its result, antibacterial action also successively decreases in time, even the situation that has antibacterial action to disappear.In addition, to have put down in writing sterilization, the anticorrosion mechanism of wrapping paper be by being discharged into the sublimed iodine (I in the packing material space to above-mentioned document 6
2) carry out, hence one can see that, and iodine can distil from substrate surface.
But, think that iodine is with teriodide ion (I in above-mentioned iodine attached middle school
3 -) or pentaiodide ion (I
5 -) form contain.
The iodine that iodine attached middle school is contained with above-mentioned ionic forms is when bringing into play bactericidal action with contacting of pollutant etc., by with this pollutant in reactions such as microorganism, organic matter such as bacterium, fungi, protozoon, virus, these ions are reduced, and generate iodide ion (I
-).
But, this iodide ion (I
-) can not enter the attached carrier of iodine (for example polyvinylpyrrolidone, cyclodextrin) regeneration iodine substantially once more attached, but disappear through antibacterial activity behind the certain hour.On the other hand, when the iodine of interpolation high concentration was attached in preparation in order to obtain effect of sufficient, anti-bacterial material presented the iodine look, has apparent problem when being applicable to the commodity of claiming " antibiotic property ".In addition, in use, might be attached to object being treated or object being treated generation corrosion etc. by the iodine look.But, even if this problem is arranged, in dealing with during certain, use anti-bacterial material, be necessary originally to exist iodine (I than the required amount excess quantity of expression effect
2) and the problem of ignorance outward appearance, corrosion.
Therefore, in utilizing the anti-bacterial material of iodine, present situation be expectation develop effectively utilize contained iodine, in order to keep the technology of the iodine of low concentration between long-term.
Thereby, the object of the present invention is to provide effective utilization of the iodine that can make in the anti-bacterial material that utilizes iodine to become possible method.
The inventor etc. further investigate in order to solve above-mentioned problem.In its process, find, when iodine such as making iodate is oxidant during with respect to excessive coexistences of iodine based compound such as iodide salts, the I that can after the performance antibiotic property, be generated by iodine
-Regeneration I
3 -, I
5 -, and then can to make iodine be oxidant plays a role as the supply source of iodine.And then, utilize the I that generates and regenerate
3 -And I
5 -Amount corresponding to the amount of interpolation iodine based compound and the phenomenon that is determined, by adding a spot of iodine based compound, keep the iodine (I of low concentration between can be stably long-term
3 -, I
5 -).That is, find to realize effective utilization of iodine, and then finish the present invention by this formation.In addition, in the solid iodophor composition (preparation) that above-mentioned Japanese kokai publication sho 63-225308 communique and Japanese kokai publication hei 2-110 communique are put down in writing, not setting forth iodine is that oxidant is that essential aftermentioned is found, iodine is that oxidant is just as being used for oxidation iodide ion (I
-) one of cited a plurality of oxidants example and being put down in writing.On the other hand, when to suppose in anti-bacterial composition of the present invention, the anti-bacterial material to use iodine be oxidant beyond the oxidant, a small amount of iodine based compound moment of coexistence was all oxidized, reaction terminating, I at short notice
3 -And I
5 =These can not regenerated to be consumed the back, so the end-of-life of anti-bacterial composition, anti-bacterial material, can not get action effect of the present invention fully.Therefore and in the embodiment that above-mentioned document is put down in writing, being iodine is the content of the content of oxidant less than iodine based compound (iodide), can not expect effectively to utilize the action effect of the present application of iodine substantially.
Specifically, a mode of the present invention is for providing a kind of anti-bacterial composition, it contains iodine based compound (A), iodine is oxidant (B) and acid compound (C), and aforementioned iodine based compound (A) and aforementioned iodine are that the mass ratio of the content of oxidant (B) is (B)/(A)=1～1000.
In addition, other modes of the present invention are for providing a kind of anti-bacterial material, it contains solid substrate and remains in the inside of described solid substrate or iodine based compound (A), the iodine on surface is oxidant (B) and acid compound (C), and described iodine based compound (A) and described iodine are that the mass ratio of the content of oxidant (B) is (B)/(A)=1～1000.Wherein, above-mentioned solid substrate is preferably sheet base material or particulate substrates.And then, above-mentioned anti-bacterial composition, anti-bacterial material can as lay-up with, dipping with, filter with, wiping with, spraying with or fill the antibacterial agent of usefulness.
Other purpose of the present invention, feature and speciality can by with reference to after explanation and the preferred implementation of accompanying drawing institute example as can be known.
Description of drawings
Fig. 1 is the sectional view of a preferred embodiment of the anti-bacterial material of expression the 2nd embodiment.
Fig. 2 is the i.e. sectional view of the optimum position embodiment of the anti-bacterial material of the 2nd embodiment of sheet anti-bacterial material of presentation layer die mould.
Fig. 3 is the figure of the situation of the laminated-type sheet anti-bacterial material of expression manufacturing the 2nd embodiment.
Embodiment
(the 1st embodiment)
According to a mode of the present invention, a kind of anti-bacterial composition is provided, it contains iodine based compound (A), iodine is oxidant (B) and acid compound (C), and aforementioned iodine based compound (A) and aforementioned iodine are that the mass ratio of the content of oxidant (B) is (B)/(A)=1～1000.In addition, " antibiotic property " among the present invention is meant the notion that suppresses microbial reproduction by iodine.In this notion, kept any of bacteriostasis that breeding suppressed by iodine though comprise bactericidal action by the iodine killing microorganisms and microorganism survival condition.Breeding is not particularly limited by the microorganism of the anti-bacterial composition of the manner and the inhibition of aftermentioned anti-bacterial material, except bacterium, also comprises virus, fungi etc.
Below, for the preferred implementation of the manner, describe each constituent in detail, but protection scope of the present invention is not limited in following concrete mode.
[iodine based compound (A)]
The anti-bacterial composition of the manner first contains iodine based compound (A).Here, " iodine based compound " is meant with moisture, organic solvent, according to circumstances contacts with air etc. and generate iodide ion (I
-) compound.This I-is that the effect of oxidant 14 is oxidized to I by the iodine that describes in detail later
3 -, I
5 -, the performance antibacterial action.But aftermentioned iodine is that the contained compound of oxidant (B) is not comprised in the notion of this iodine based compound (A).
For the concrete kind of iodine based compound (A), promptly be not particularly limited so long as show the compound of above-mentioned effect.As an example, can enumerate potassium iodide (KI), sodium iodide iodide salts such as (NaI) etc.In addition, according to circumstances, can also be with the simple substance (I of iodine molecule
2) as iodine based compound (A).In addition, these iodine based compounds (A) can only use a kind separately, can also be also with more than 2 kinds.
[iodine is oxidant (B)]
It is oxidant (B) that the anti-bacterial composition of the manner second contains iodine.Here, " iodine is oxidant " is meant and can generates the I that above-mentioned iodine based compound (A) can be generated
-Be oxidized to I
3 -, I
5 -The compound of active specy.As the object lesson of aforementioned active specy, for example can enumerate hypoiodous acid ion (IO
-), acid iodide ion (IO
3 -) and periodic acid ion (IO
4 -).These ions with concentration along with the I that increases with contacting of moisture
-Oxidation changes I into
3 -, I
5 -If explain this mechanism, then I
-By the effect of each active specy, according to following chemical equation (1)～(3):
IO
-+I
-+2H
+→I
2+H
2O ······ (1)
3IO
3 -+I
-+18H
+→2I
2+9H
2O ·· (2)
IO
4 -+I
-+8H
+→I
2+4H
2O ····· (3)
Be oxidized to iodine molecule (I
2), and then, by with water in other I
-Reaction generates I
3 -, I
5 -The I that generates like this
3 -, I
5 -, can bring into play antibacterial action once more.That is, realize effective utilization of iodine.Further, the I that is regenerated
3 -, I
5 -Amount depend on I
-Amount, therefore can be by the anti-bacterial composition of the manner with I
3 -, I
5 -Amount remain at low concentration.Its result, the long lifetime of anti-bacterial composition becomes possibility, and the problem of corrosivity, tone also can be eliminated.In addition, above-mentioned mechanism infers only that also even if obtain action effect of the present invention by the mechanism beyond above-mentioned, protection scope of the present invention can not be affected yet.
In addition, among the present invention, iodine is that oxidant (B) not only plays a role as the supply source of above-mentioned active specy, by the reaction of above-mentioned reaction equation (1)～(3), can also play a role as the supply source of iodine.Therefore, according to the present invention, the compound that contains iodine by employing can further be brought into play the such action effect of the present invention of effective utilization of iodine as being used for the oxidant that the oxidation iodide ion generates iodine molecule.When to use iodine be oxidant beyond the oxidant, can't obtain these effects as mentioned above.
Iodine is that the concrete kind of oxidant (B) is not particularly limited, so long as by getting final product with the compound that can generate above-mentioned active specy that contacts of moisture.As an example, can enumerate hypoiodous acid (HIO), acid iodide (HIO
3), para-periodic acid (HIO
4), periodic acid (H
5IO
6) wait acid iodide class, the slaine of aforementioned acid iodide class (for example sodium salt, sylvite etc.), I (IO
3)
3Deng salt compounded of iodine and iodous acid (I
2O), three iodine oxide (I
2O
3), iodine pentoxide (I
2O
5), seven iodine oxide (I
2O
7), four iodine oxide (IO
4) wait oxyiodide.In addition, these iodine are that oxidant (B) can only use a kind separately, can also be also with more than 2 kinds.
[acid compound (C)]
By chemical equation (1)～(3) as can be known, by I
-Generate I
3 -, I
5 -Mechanism in, hydrogen ion is consumed.Therefore, when anti-bacterial composition of the present invention contacts with moisture, in order to generate I
3 -, I
5 -,, must show acidity with the contacted moisture of the anti-bacterial composition of the manner in order to carry out above-mentioned mechanism.Thereby the anti-bacterial composition the 3rd of the manner contains acid compound (C).Here, " acid compound " is meant by making this moisture become acid compound with contacting of moisture.For example, except acid, can also enumerate the salt of strong acid and weak base generation etc.Object lesson for acid compound is not particularly limited, if lift an example, can enumerate citric acid monohydrate compound, succinic acid, malic acid, oxalic acid, tartaric acid etc. as acid.Can also use these derivatives such as hydrate.In addition, as the acid compound beyond the acid, except the salt that strong acid such as ammonium chloride, ammonium sulfate, ammonium iodide and weak base generate, can also use niter cake, potassium dihydrogen phosphate, as the chloration hydro-oxidation magnesium (Mg (OH) Cl) of basic salt etc. as ackd salt.In addition, these acid compounds (C) can only use a kind separately, can also be also with more than 2 kinds.
More than, the concrete formation of each composition that the manner anti-bacterial composition is contained has been described, the content of each composition of anti-bacterial composition is not particularly limited, and having or not etc. of the stoichiometric proportion by considering above-mentioned chemical equation (1)～(3), manufacture method, additive can suitably be regulated.But in the anti-bacterial composition of the manner, iodine based compound (A) and iodine are that the ratio of the content of oxidant (B) is controlled at the value in the prescribed limit.Specifically, iodine based compound (A) and iodine are that the mass ratio of the content of oxidant (B) is controlled at (B)/(A)=1～1000.Like this, when the content of each composition of control makes that iodine is that the content of oxidant (B) reaches the content of iodine based compound (A) when above, above-mentioned mechanism is carried out well, can effectively utilize iodine contained in the composition.In addition, preferred (B)/(A)=5～200, more preferably (B)/(A)=10～100.Here, when the value of (B)/(A) was too small, the number of times that carries out of reaction shown in above-mentioned chemical equation (1)～(3) reduced, the regeneration of iodine as a result between short-term in end, can not fully obtain to realize the action effect of the present invention of effective utilization of iodine.
In addition, as long as satisfying afore mentioned rules, the content separately of contained each composition of anti-bacterial composition then is not particularly limited.Wherein, in preferred mode, the content of iodine based compound (A) so long as the oxidized and iodine performance antibacterial action institute that generates fully amount get final product, with respect to total composition, be preferably 0.001～10 quality %, more preferably 0.005～5 quality %, 0.01～3 quality % more preferably.In addition, be the content of oxidant (B) for iodine, be controlled at value in the above-mentioned scope with the mass ratio of iodine based compound (A), and then for acid compound (C), can use that to be used to make whole iodine be oxidant (B) reaction institute amount fully.Therefore, iodine is that the content of oxidant (B) is preferably 1～95 quality %, more preferably 5～90 quality %, 10～80 quality % more preferably with respect to total composition.In addition, the content of acid compound (C) is preferably 1～95 quality %, more preferably 5～90 quality %, 10～80 quality % more preferably with respect to the total amount of composition.Here, when the content of iodine based compound (A) was too much, the primary quantity of iodine and regeneration amount (being the maintenance dose of iodine concentration) became too much, might be able to not give full play to the such action effect of the present invention of stabilisation that improves the iodine under corrosivity, tone, the low concentration.On the other hand, when iodine is the content of oxidant (B) when too much, the amount that consumes whole iodine and be the required acid oxidase thing (C) of oxidant (B) increases, the danger that has the acidity degree of spending of anti-bacterial composition to rise.In addition, when adding the various additive of aftermentioned, as the content of (A)～(C) of essential component in the anti-bacterial composition situation of the above-mentioned scope of disengaging is arranged, even if also can be included in protection scope of the present invention in this case.
In addition, in TOHKEMY 2000-507217 communique, Japanese kokai publication sho 59-202248 communique, Japanese kokai publication sho 56-99419 communique, Japanese kokai publication sho 53-148540 communique etc., also disclose contain the iodine based compound, iodine is the bactericidal properties composition of oxidant and acid compound.But, in the technology that these documents are put down in writing, iodine be oxidant be for the iodine that makes other interpolation or iodine attached stable and add, for the combination that is oxidant by a spot of iodine based compound and a large amount of iodine and with I
3 -, I
5 -Maintain the purpose of the application under the low concentration and action effect without any enlightenment.And, even if the invention that these documents are put down in writing use iodine be material beyond the oxidant as oxidant, also can expect equal effect, iodine is that oxidant is only put down in writing side by side with other oxidant.
The anti-bacterial composition of the manner can also further contain other additive as required.Concrete mode for other additive is not particularly limited, can be suitably with reference to existing known knowledge.As preferred additives, for example can enumerate the compound that can form complex with iodine.As the compound that can form complex, for example can enumerate cyclodextrin (CD), polyvinylpyrrolidone (PVP), glycine etc. with iodine.By adding these compounds, the sublimability of iodine and corrosivity are relaxed.Wherein, preferably contain cyclodextrin.The interpolation of cyclodextrin also brings all cpds bag in the pollutant is connected on deodorizing effect in self circulus except above-mentioned effect." cyclodextrin " is meant that D-glucose is combined into the compound of ring-type by α-1,4 bond.Cyclodextrin is by the number of the D-glucose of formation self, and rough classification is alpha-cyclodextrin (6), beta-schardinger dextrin-(7) and gamma-cyclodextrin (8).In the anti-bacterial composition of the manner, can use wherein any.
The concrete mode of cyclodextrin is not particularly limited, and can suitably adopt existing known mode.Not only can use 3 kinds of above-mentioned cyclodextrin, can also use their derivative.As the object lesson of cyclodextrine derivatives, can enumerate the derivative of alkylation (methylate, ethylization, propylated, isopropylation, butylation etc.), monoacylphosphineization, triacetylization, monochloro triazinylization.As the object lesson of cyclodextrin, for example can enumerate as CAVAMAX (registration mark) series, CAVASOL (registration mark) series by commercially available commodity (be Wacker Co., Ltd. produces).In addition, can also use as Dexypearl, Isoelite (the international biological study in Co., Ltd. Yokohama is produced) by other cyclodextrin such as commercially available malt-base (maltosyl group) substituted type cyclodextrin.In addition, these cyclodextrin can only use a kind separately, can also be also with more than 2 kinds.
As mentioned above, cyclodextrin contained in the anti-bacterial composition can be brought into play deodorization by all cpds bag in the pollutant is connected in the circulus of self.In addition, in the manner, the cyclodextrin bag was connected the I that above-mentioned mechanism generates
3 -, I
5 -Thereby, can generate as a kind attached iodo-cyclodextrin bag of iodine and connect compound (CDI).Therefore, I
3 -, I
5 -Resolve into I
2And the possibility of distillation reduces the raising of the antibiotic continuation when anti-bacterial composition is used in expectation.In addition, according to circumstances, in the anti-bacterial composition of the manner, part or all of cyclodextrin can also be originally just connects the form that cyclodextrin-iodine bag that iodine forms connects compound with bag and contains.In addition, the anti-bacterial composition of the manner contains in the time of can forming the compound of complex with iodine, this can be not particularly limited with the content that iodine forms the compound of complex, with respect to the total amount of composition, be preferably 0～90 quality %, more preferably 0～80 quality %, 0～70 quality % more preferably.
In addition, the anti-bacterial composition of the manner can also contain known antibiotic, synthetic antibacterial agents etc. where necessary.As known antibiotic, for example can enumerate mould prime system, cephem system, carbapenem system, monobactam and be beta-lactam such as antibiotic is antibiotic; Aminoglycoside antibiotics; The macrolide antibiotic; Terracycline antibiotics; Chloramphenicol; Lincomycin, phosphonomycin; Peptide is antibiotic and antifungal activity antibiotic etc.As synthetic antibacterial agents, can enumerate acidum nalidixicum, Novel Quinolone series antibacterial agent and thiazole is antifungal agent etc.In addition, be not limited in above-mentioned substance, also all cpds as external application agent, disinfectant can be added as additive.According to circumstances, can also add antivirotic.In addition, illustrated additive can only use a kind separately, can also be also with more than 2 kinds.
The anti-bacterial composition of the manner can be that above-mentioned (A)～(C) must component and the powdered composition that mixes of the additive that adds as required, can also be the water-soluble aqueous composition that further contains water.By the form of the aqueous solution, processing and preservation become simply, owing to can pass through uses such as spraying, distribution, therefore have the advantage that scope applicatory becomes wideer.In addition, when the composition of the manner further contained water, the addition of water was not particularly limited, with respect to the total amount of composition beyond the water, be preferably 1～2000 quality doubly, more preferably 2～1000 quality doubly, more preferably 20～500 quality are doubly.Certainly can also adopt the mode that breaks away from these scopes.
In addition, the manufacture method of the anti-bacterial composition of the manner is not particularly limited, can be suitably with reference to the existing known knowledge relevant with the manufacturing of powdered composition, water-soluble liquid composition.For example, when making powder the shape composition, can adopt following method: prepare the constituent of composition, with the suitably granulation of each composition of being prepared, be ground into required particle diameter, the method for mixing equably by mixer etc.According to circumstances, can also when mixing, carry out granulation, pulverizing.In addition, when desire was made water-soluble aqueous composition, can also make with the following method: the constituent of the composition of weighing ormal weight was also added in the water, makes the method for its dissolving by stirring.Wherein, can also use said method method in addition certainly.
(the 2nd embodiment)
According to alternate manner of the present invention, a kind of anti-bacterial material is provided, its comprise solid substrate and remain in described solid substrate inside or the surface iodine based compound (A), iodine be oxidant (B) and acid compound (C), described iodine based compound (A) and described iodine are the mass ratio (B)/(A)=1～1000 of the content of oxidant (B).
Below use the preferred implementation of description of drawings the manner.Wherein, protection scope of the present invention is not limited to following manner and illustrated mode.For example; in the following description; enumerating as solid substrate has used the sheet anti-bacterial material of sheet base material to explain the anti-bacterial material of the manner as an example; but be not limited in mode as described above, use the aftermentioned particulate substrates to be also contained in protection scope of the present invention as the granular anti-bacterial material of solid substrate.
Fig. 1 is the sectional view of a preferred implementation of expression the manner anti-bacterial material.The anti-bacterial material of mode shown in Figure 1 is a sheet anti-bacterial material 10.That is, use sheet base material 12 as solid substrate.Sheet anti-bacterial material 10 shown in Figure 1 have in the inside of sheet base material 12 maintain iodine based compound (A) 14, iodine is the formation of oxidant (B) 16 and acid compound (C) 18.In addition, in mode shown in Figure 1, each composition only remains in the inside of sheet base material 12, but is not limited in this mode.For example, can adopt above-mentioned each composition only to remain in the mode on the surface of sheet base material 12, remain in the inside of sheet base material 12 and surperficial both sides' mode.In addition, when each composition remains in sheet base material 12 surperficial, can only remain in the single face of sheet base material 12, also can remain in the two sides of sheet base material 12.
[sheet base material]
The sheet anti-bacterial material 10 of mode shown in Figure 1 has sheet base material 12 as solid substrate.
The concrete mode of sheet base material 12 is not particularly limited.As the composition material of employed sheet base material 12 in the sheet anti-bacterial material 10 of the manner, for example can enumerate paper, fabric, nonwoven etc.Comprise Japan paper, filter paper, drawing paper, high-quality paper, corrugated paper (corrugated paper), cardboard (cardboard), recycled writing paper, synthetic paper, white board, yellow plate paper, chipboard, colour table paper, building materials body paper, paperboard, tissue paper, heat-sensitive paper, artifical fibre paper etc. in the paper.As the raw material of fabric and nonwoven, can also use any of organic fiber and inorfil.Here, organic fiber comprises vegetable fiber, animal fiber, regenerated fiber, semisynthetic fibre and synthetic fibers.In addition, inorfil comprises glass fibre, carbon fiber, ceramic fibre etc.As vegetable fiber, except enumerating woodies such as wood pulp, yellow pulp, bamboo pulp, mestha paper pulp, can also enumerate draft class, cotton, fiber crops etc., can enumerate fibers such as thin,tough silk, wool as animal fiber.As regenerated fiber, can enumerate rayon fiber, cuprammonium rayon etc., as semisynthetic fibre, acetate fiber, triacetate fiber, Promix (Promix) fiber etc. can be enumerated, fibers such as nylon fiber, acrylic fiber, vinylon fiber, inferior vinyl fiber, polyvinyl chloride fibre, polyester fiber, polyethylene fibre, polypropylene fibre, benzoate fibre, ripple Rec Le Er (polyclar) fiber, phenol fibre can be enumerated as synthetic fibers.In addition,, commercially available product can also be used, oneself synthetic product can also be used as sheet base material 12.
Size, the shape of sheet base material 12 are not particularly limited, and can suitably determine according to the purposes of sheet anti-bacterial material.
For the concrete mode of the kind of each composition that remains in sheet base material 12 etc. and since with the 1st embodiment in illustrated same, therefore omission will be described here.
In the anti-bacterial material of the manner, when each composition remained in solid substrate, iodine based compound (A) and iodine were that the mass ratio of the content of oxidant (B) is controlled to be (B)/(A)=1～1000.Too, so that iodine is the content of oxidant (B) is the content of iodine based compound (A) when above, above-mentioned mechanism is carried out well when the content of each composition of control in the anti-bacterial material of the manner, and iodine contained in the anti-bacterial material can be effectively utilized.
In addition, in the anti-bacterial material of the manner,, the content separately of contained each composition then is not particularly limited as long as satisfying afore mentioned rules.For example, the content of iodine based compound (A) is so long as the concentration of the iodine that oxidation generated is to show the sufficient amount of antibacterial action institute to get final product, and according to the kind (for example nonwoven, paper) of solid substrate, its proportion also changes, therefore very difficult regulation uniformly.Wherein, in preferred mode, the content of iodine based compound (A) is preferably 0.00001～20 quality %, more preferably 0.0001～5 quality %, 0.0001～1 quality % more preferably with respect to the total amount of anti-bacterial material.In addition, iodine is that the content of oxidant (B) is controlled at mass ratio with iodine based compound (A) and reaches value in the above-mentioned scope, and then can to use whole iodine for acid compound (C) be oxidant (B) reaction institute amount fully.
When sheet anti-bacterial material 10 contacts with moisture in use, generate I by above-mentioned mechanism
3 -, I
5 -These ions are owing to present the iodine look, thus the sheet anti-bacterial material of the manner can use by visual identification before or use after any situation.Wherein, in the sheet anti-bacterial material 10 of the manner, by the recycling iodine of above-mentioned mechanism.Be identified as the situation of " using the back " even if therefore present the iodine look, also can bring into play antibacterial action fully.
In the anti-bacterial material of the manner, can also further keep other additive at solid substrate as required.As the additive that can further remain in solid substrate, for example can enumerate the additive that in the anti-bacterial composition of the 1st embodiment, illustrates.
In addition, in the manner, can also effectively utilize other additive.For example, though iodine shows antibacterial action, the iodine look also tone with general pollutant is close.Therefore, in case present the sheet anti-bacterial material 10 that utilizes the manner behind the iodine look once more, can take place attractive in appearance on preferred situation.Viewpoint is set out thus, in the sheet anti-bacterial material 10 of the manner, can keep starch, its derivative at sheet base material 12.By this mode, when generating I by above-mentioned mechanism
3 -, I
5 -The time, they and starch or derivatives thereof form complex, present bright-coloured bluish violet (so-called " starch-iodine reaction ").Therefore, can reduce because once the colour generation of used sheet anti-bacterial material 10 was caused to harmful effect attractive in appearance.In addition, I
3 -, I
5 -Even if, also can bring into play antibacterial action with starch, when its derivative forms complex.
And then, as other additive, for example when solid substrate is paper, can keep with cationic starch or amphoteric starch is brightener, surfactant, spices, pigment, the pigment etc. such as various sizing agents such as pigment such as dyestuff, chrome yellow, rosin, starch, animal glue, carboxymethyl cellulose, polyvinyl alcohol, glycerine such as various fillers such as paper strengthening agent, talcum, diatomite and titanium oxide, aniline such as inner adhesive, polyacrylamide of principal component.In addition, solid substrate is during by fibrous fabric, nonwoven, can keep antistatic additive, stabilizing agent, anti-yellowing agent, lubricant etc.
The sheet anti-bacterial material 10 of the manner can be dry, also can be moistening.Wherein, from the viewpoint of reduction for the stability of corrosion of metal, raising iodine, preferably dry.Here, when the sheet anti-bacterial material 10 of the manner is moistening,, for example can enumerate water, aqueous alcohol, surfactant etc. as containing the immersion liquid that contains that is immersed in the sheet anti-bacterial material 10.
In addition, the sheet anti-bacterial material 10 of the manner can also be laminated-type.As the form of the sheet anti-bacterial material 10 of laminated-type, for example can enumerate form shown in Figure 2.Fig. 2 is the sectional view of presentation layer die mould sheet anti-bacterial material.In form shown in Figure 2, sheet anti-bacterial material 10 is made of the 1st sheet material 10A and the 2nd sheet material 10B.The 1st sheet material 10A has the composition that only maintains iodine based compound (A) 14 at the 1st sheet base material 12A.On the other hand, the 2nd sheet material 10B has at the 2nd sheet base material 12B and maintains the composition that iodine is oxidant (B) 16 and acid compound (C) 18.
As shown in Figure 2, iodine based compound (A) 14 is that oxidant (B) 16 remains in the laminated-type sheet anti-bacterial material 10 that different solid substrates form with iodine, owing to do not present the iodine look before use substantially, and therefore preferred.And, owing in manufacturing process, there is not I
3 -, I
5 -, therefore also preferred from the viewpoint of the corrosion that can prevent to make machine.Wherein, protection scope of the present invention is not limited to the iodine look shallow form that sheet anti-bacterial material 10 is presented.The reason that the iodine look that the sheet anti-bacterial material 10 of mode shown in Figure 2 is presented reduces describes in detail in following manufacture method.In addition, as shown in Figure 2, acid compound (C) 18 is when remaining in different solid substrates with iodine based compound (A) 14, in other words, when being the solid substrate of oxidant (B) when keeping acid compound (C) 18 maintaining iodine, that can remove fully that the influence of acid compound (C) causes generates iodine (I by iodine based compound (A)
3 -, I
5 -) possibility, be preferred from this viewpoint.
Here, each sheet material (10A, 10B) and the main body to each sheet material that constitutes the sheet anti-bacterial material 10 of form shown in Figure 2 is that the term of each sheet base material (12A, 12B) " the 1st " and " the 2nd " labeled is only in order to represent that iodine based compound 14 and iodine are that oxidant 16 and acid compound 18 are held in different respectively sheet base materials, constitute different sheet materials and the term of expedient use separately.Therefore the ordering itself of " the 1st " and " the 2nd " there is no special meaning.In addition, the raw material of the raw material of the 1st sheet base material 12A and the 2nd sheet base material 12B can be identical, also can be different.
In addition, when the anti-bacterial material of the manner was the sheet anti-bacterial material, each composition remained in the form of sheet base material and not only is confined to form shown in Figure 2, can also adopt form arbitrarily.For example, except form shown in Figure 2, (1) iodine based compound (A) and iodine are that oxidant (B) remains in the form that the 1st sheet base material, acid compound (C) remain in the 2nd sheet base material; (2) iodine based compound (A) and acid compound (C) remain in the 1st sheet base material, iodine is the form that oxidant (B) remains in the 2nd sheet base material; (3) iodine based compound (A) remains in the 1st sheet base material, iodine is that oxidant (B) remains in the 2nd sheet base material, acid compound (C) remains in the 3rd sheet base material (wherein, the lamination of the 1st～the 3rd sheet base material order is unqualified) form etc., can adopt various forms.
Perhaps, the sheet anti-bacterial material 10 of the manner can also be that single or double at the sheet anti-bacterial material 10 of mode illustrated in figures 1 and 2 further disposes the laminated-type sheet material that the sheet material beyond the sheet anti-bacterial material of the manner forms.As mentioned above, the sheet anti-bacterial material of the manner has the situation that presents the iodine look in use.In this case, by making the laminated-type sheet material with other sheet material lamination, the sheet anti-bacterial material that then presents the manner of iodine look is coated, and can improve outward appearance.In this laminated-type sheet material, be attached to the layer that the contamination by micro thing can diffuse to the manner sheet anti-bacterial material that contains of laminated-type sheet surface, so antibacterial action can be brought into play fully.In addition, in the sheet anti-bacterial material 10 of mode shown in Figure 2, between the 1st sheet material 10A and the 2nd sheet material 10B, can also dispose the manner the sheet anti-bacterial material, constitute the sheet material beyond the sheet material of this material.In this laminated-type sheet material, antibacterial action can be brought into play fully.In addition, when the sheet anti-bacterial material of the manner is made the laminated-type sheet material, be not particularly limited, for example can adopt the formed sheet material of the base material that can be used in the manner as the sheet material that on the sheet anti-bacterial material basis of the manner, can dispose.
The manufacture method of the sheet anti-bacterial material 10 of the manner is not particularly limited.
The sheet anti-bacterial material 10 of form shown in Figure 1 for example can contain the dipping solution that desire keeps composition, impregnated sheet shape base material 12 in this solution, the method manufacturing that is dried after the taking-up by modulation.Process sequence below is described.
At first, prepare appropriate solvent, the above-mentioned iodine based compound of interpolation (A) 14, iodine are oxidant (B) 16 and acid compound (C) 18 in the solvent of being prepared, thus the modulation dipping solution.At this moment, when desire also remains in sheet base material 12 with the composition beyond the mentioned component, the composition that desire keeps can also be added in the dipping solution simultaneously.In addition, according to existing known knowledge, except these additives,, can also add other additives such as stabilization agent in order to change the characteristic of solution.Be not particularly limited for the solvent of being prepared, can make water, ethanol, methyl alcohol, toluene, ethyl acetate, acetone, oxolane, dimethyl sulfoxide (DMSO) and their mixed solvent etc.From in order fully to dissolve the viewpoint of above-mentioned each composition, can preferably make water or be the solvent of principal component with water.
Then, the sheet base material of preparing in addition 12 is immersed in the dipping solution of above-mentioned modulation.Thus, each contained composition remains to the inside and the surface of sheet base material 12 in the dipping solution.Actual temp condition, dip time during for dipping are not particularly limited, can be suitably with reference to existing known knowledge.
Afterwards, from dipping solution, take out sheet base material 12, be dried.Dry concrete grammar is not particularly limited, and can adopt natural seasoning, can also adopt the force drying that utilizes heating, air-supply to carry out.Temperature condition, drying time during heating are not particularly limited, and can suitably set with reference to existing known knowledge.
More than, for example understand the mode that contained each composition in the dipping solution is remained in inside with the surface of sheet base material 12 by infusion process, but the manufacture method of sheet anti-bacterial material 10 of the present invention is not limited to aforesaid way.For example, can also adopt by methods such as spraying coating or roller apposition methods the solution coat of above-mentioned modulation method on the surface of sheet base material 12.Then, can also implement same drying after coating handles.By this mode, can make the sheet anti-bacterial material 10 of mode that each composition in the solution remains in the surface of sheet base material 12.And then if possible, can also adopt further raw material to add the method for carrying out papermaking in the above-mentioned dipping solution to sheet base material 12.
According to alternate manner of the present invention, provide the preferable production process of above-mentioned sheet anti-bacterial material.By the manufacture method of the manner, can make the sheet anti-bacterial material of mode shown in Figure 2.That is, the manner is the sheet anti-bacterial material manufacture method with following operation: dipping the 1st sheet base material in the solution that dissolving iodine based compound (A) forms in solvent, to keep the operation of aforementioned iodine based compound (A) at aforementioned the 1st sheet base material; Dissolving iodine is to flood the 2nd sheet base material in the solution that forms of oxidant (B) and acid compound (C) in solvent, is the operation of oxidant (B) and aforementioned acid compound (C) to keep aforementioned iodine at aforementioned the 2nd sheet base material; The operation of dry aforementioned the 1st sheet base material and the 2nd sheet base material; The operation of aforementioned the 1st sheet base material of lamination and aforementioned the 2nd sheet base material.As a reference, in Fig. 3, express the situation of making laminated-type sheet anti-bacterial material by the manufacture method of the manner.
The manufacture method of the manner as shown in Figure 3, modulation contains the dipping solution of iodine based compound (A) and contains the dipping solution that iodine is oxidant (B) and acid compound (C) respectively, flood sheet base material 12 separately respectively and keep each composition, make sheet anti-bacterial material 10 by each sheet base material 12 of lamination, in addition, the above-mentioned manufacture method with the sheet anti-bacterial material of mode shown in Figure 1 is identical.
The sheet anti-bacterial material 10 of the mode shown in Figure 2 of the manufacture method manufacturing by the manner as mentioned above, does not present the iodine look before use substantially.The following explanation of its reason.
That is, when primary modulation contained the dipping solution of the whole compositions that keep to some extent, in this dipping solution, the reaction shown in above-mentioned chemical equation (1)～(3) was carried out.Therefore, generation I to a certain degree
3 -, I
5 -, I
2, these also are held in keeping operation, so the sheet anti-bacterial material 10 of manufacturing presents iodine look to a certain degree.Relative therewith, according to the manufacture method of the manner,, therefore can not generate the I that presents the iodine look because each composition that is kept can once not coexist as in the dipping solution
3 -, I
5 -, I
2Thereby the sheet anti-bacterial material of the manufacture method manufacturing by the manner does not present the iodine look before use substantially.Therefore, can make the preferred sheet anti-bacterial material 10 of attractive in appearance by the manufacture method of the manner.And, owing in manufacturing process, there is not I
3 -, I
5 -, therefore also preferred from the viewpoint of the corrosion that can prevent to make machine.
In the manner manufacture method, behind the required separately composition that has kept the 1st sheet base material 12A and the 2nd sheet base material 12B,, make the sheet anti-bacterial material 10 of laminated-type with its lamination.At this moment, can from each dipping solution, take out each sheet base material 12 after, before drying, carry out lamination, also can behind lamination, carry out drying; After can also taking out each sheet base material 12 from each dipping solution, dry each sheet base material 12 carries out lamination after drying.Never generate I by above-mentioned mechanism
3 -, I
5 -, I
2Viewpoint set out, can preferably adopt the mode of carrying out lamination after the drying.
Laminating method when making the laminated-type sheet material by each sheet base material 12 of lamination is not particularly limited, and can suitably adopt existing known method in the manufacturing field of laminate.When selecting laminating method, preferably consider composition that remains in the 1st sheet base material 12A and the composition that remains in the 2nd sheet base material 12B are not reacted when lamination substantially.As an example of laminating method, for example can enumerate overlapping the 1st sheet base material 12A and the 2nd sheet base material and make layered product, only with the method for the peripheral part heat bonding of this layered product.Certainly can also adopt other method.
The form of the maintenance dose of the sheet anti-bacterial material 10 of the manner by suitably regulating each composition, solid substrate etc. goes for various uses.For example, by using the sheet anti-bacterial material 10 of the manner containing interval that the contamination by micro thing can adhere to, pollutant is attached to the sheet anti-bacterial material 10 of the manner, by contacting the iodide ion (I that generates with moisture in the accompanying pollutant
-), iodine is oxidant (IO
-, IO
3 -, IO
4 -) and proton (H
+), generate I by mechanism shown in above-mentioned chemical equation (1)～(3)
3 -, I
5 -, thus can be effectively with contained microbial disinfection.That is performance antibacterial action.
Thus, as the concrete purposes of the sheet anti-bacterial material 10 of the manner, for example can enumerate as the lavatory and be layered on pad on the ground in lavatory, in the research facilities of handling microorganism, be layered on experimental bench or the ground, be layered on as medical sheet material on the operating desk or ground of medical treatment office, be layered on sheet material in pet litter box or the birdcage, be layered on kitchen worktop or ground lay-up is used as kitchen paper as pet as the experimental bench sheet material; Be immersed in by the dipping in the solution of microbial contamination as dipping sterilization sheet material and use; Be installed in air-conditioning, air purifier and the dust catcher etc. as the filtration of filter and mode such as use, not limited thereto.In addition, in above-mentioned various places, can also be used in the wiping that is used for the wiping pollutant certainly and use.
(the 3rd embodiment)
More than; enumerate composition and the manufacture method thereof of having used the sheet base material to understand anti-bacterial material of the present invention in detail as the sheet anti-bacterial material of solid substrate; but protection scope of the present invention should be determined according to the record of claims, be not limited only to the mode of sheet.
As the mode beyond the sheet of the anti-bacterial material of the manner, can enumerate and for example use the granular mode of particulate substrates as solid substrate.That is, solid substrate also is provided is the anti-bacterial material of particulate substrates to the application.
The anti-bacterial material of the manner is except being shaped as of solid substrate is granular, and is same with above-mentioned sheet anti-bacterial material.Therefore omit detailed explanation here.
The particle diameter of particulate substrates is not particularly limited, and can suitably determine according to the purposes of granular anti-bacterial material.
In the anti-bacterial material of the manner, each composition that illustrates in the 1st embodiment is included in the particulate substrates.At this moment, the mode that contains of each composition is not particularly limited.For example, can be the mode that oxidant (B) and acid compound (C) all remain in same particulate substrates for iodine based compound (A), iodine.The conceptive sheet anti-bacterial material of this mode corresponding to mode shown in Figure 1.In addition, the granular anti-bacterial material of the manner can also be that to maintain the 1st bulk material of iodine based compound (A) and maintain iodine in the 2nd particulate substrates in the 1st particulate substrates be the mixed type mode that the 2nd bulk material of oxidant (B) and acid compound (C) mixes.This mode is conceptive corresponding to laminated-type sheet anti-bacterial material shown in Figure 2.But be not only to be confined to these modes, for example can adopt (1) iodine based compound (A) and iodine is that oxidant (B) remains in the mode that the 1st particulate substrates, acid compound (C) remain in the 2nd particulate substrates; (2) iodine based compound (A) and acid compound (C) remain in the 1st particulate substrates, iodine is the form that oxidant (B) remains in the 2nd particulate substrates; (3) iodine based compound (A) remains in the 1st particulate substrates, iodine is that oxidant (B) remains in the 2nd particulate substrates, acid compound (C) remains in the 3rd particulate substrates, the variety of ways such as mode that these particulate substrates mix equably.
The shape and size of particulate substrates also are not particularly limited.The shape of particulate substrates can also be cuboid, indefinite form shape for spherical.In addition, to being called as the granular degree, the large-size that can also use impression such as causing bulk or solids is as particulate substrates except little for size.
The anti-bacterial material manufacture method of the manner is not particularly limited.In the manufacture method of the anti-bacterial material of above-mentioned the 2nd embodiment,, can make the granular anti-bacterial material of the manner by used solid substrate is replaced with particulate substrates by the sheet base material.In addition, according to the thought identical with the anti-bacterial material manufacture method of above-mentioned the 2nd embodiment, by keeping iodine based compound (A) in the 1st particulate substrates, keeping iodine in the 2nd particulate substrates is oxidant (B) and acid compound (C), the 1st particulate substrates and the 2nd particulate substrates that will maintain each composition are then mixed, thereby can make the granular anti-bacterial material of mixed type.
As granular the manner anti-bacterial material, can suitably regulate the mode of the content, solid substrate etc. of each composition, thereby, go for various uses, performance antibiotic property by the mechanism same with the sheet anti-bacterial material.And this moment, can effectively utilize iodine.
Concrete purposes as granular the manner anti-bacterial material, for example can enumerate the lay-up that is layered on the pet litter box bottom as pet litter box sand with, as quilt with or the pillow filling that is filled in quilt or pillow inside with packing material form such as use, but be not limited thereto.
Embodiment
Below use embodiment that the present invention is described in further detail, but protection scope of the present invention is not only to be confined to following manner.
＜embodiment 1 〉
Adding as the potassium iodide (KI) (0.109 quality %) of iodine based compound (A), as iodine in water is the Potassiumiodate (KIO of oxidant (B)
3) (1.0 quality %), as the citric acid monohydrate compound (2.0 quality %) of acid compound (C), as α-CD (3.0 quality %) and the methyl β-CD (2.0 quality %) of cyclodextrin (CD), prepare the 100mL aqueous solution that dissolves by stirring.
In the aqueous solution of above-mentioned preparation, add 1 quality % starch test solution 10mL, obtain blue liquid by starch-iodine reaction.
When in this blue liquid, dripping 0.02N sodium thiosulfate liquid while stirring, because the reduction of iodine and blue the disappearance, but when continuing to stir, can recover with initially equal blueness when the dropping that stops sodium thiosulfate liquid.And, when dripping above-mentioned sodium thiosulfate liquid once more while stirring, because the reduction of iodine and blue the disappearance, but when continuing to stir, can recover once more with initially equal blueness when the dropping that stops sodium thiosulfate liquid.
As known from the above, in the aqueous solution of present embodiment, be present in the iodide ion (I in the aqueous solution
-) constantly be regenerated as iodine (I
3 -, I
5 -).
＜embodiment 2 〉
By the following method, according to manufacture method shown in Figure 3, make laminated-type sheet anti-bacterial material shown in Figure 2.
[modulation of dipping solution]
At first, as the solvent of the 1st dipping solution, prepare water.In this water, add as the potassium iodide (KI) (0.109 quality %) of iodine based compound (A) and as α-CD (3.0 quality %) and the methyl-β-CD (2.0 quality %) of cyclodextrin (CD),, modulate the 1st dipping solution with stirring by mixing.
On the other hand, prepare and the solvent of above-mentioned same water as the 2nd dipping solution.Adding as iodine in this water is the Potassiumiodate (KIO of oxidant (B)
3) (1.0 quality %), as the citric acid monohydrate compound (2.0 quality %) of acid compound (C) and with above-mentioned same methyl-β-CD (5.0 quality %), mix equably by stirring, modulate the 2nd dipping solution.
As solid substrate, with commercially available paper pulp weaving thing (Sun Japan Corp. system; " Paper Chemical Dust Cloth ", thick size) size that is cut into 5cm * 5cm amounts to 2, prepares the 1st and the 2nd sheet base material.
In the 1st and the 2nd dipping solution of above-mentioned modulation, flood the 1st and the 2nd sheet base material of above-mentioned preparation respectively, placed 1 minute down, make each composition in the dipping solution remain in the sheet base material at 25 ℃.
Then, from each dipping solution, take out each sheet base material,, make each sheet base material drying its 80 ℃ of hot blasts that blow dryer generation in 30 minutes.
Afterwards, behind each sheet base material of lamination, utilize fixedly layered product of clip, make the antibacterial sheet of present embodiment.
When the central portion of the antibacterial sheet of making drips 1 quality % amidin, drip the position and present bright-coloured bluish violet, confirm that so-called starch-iodine reaction carries out.The colour generation that this starch-iodine reaction caused can not disappear at short notice, keeps about a few hours.
＜embodiment 3 〉
After many of commercially available paper handkerchiefs (Elleair (registration mark), Daio Seishi KK produce) are peeled off, be cut into the size of 3cm * 3cm, be impregnated in the water back and take out, utilize finger tip group to become the wheat size except that anhydrating.Then, use infrared absorption spectrometry under the pressure of 300kg, to pressurize it is solidified, obtain granular solid substrate with the KBr tablet press machine.Afterwards, the gained solidfied material is divided into 2 groups, makes its natural seasoning.
Afterwards, in one group, drip the 1st dipping solution of the foregoing description 1 modulation, drip the 2nd dipping solution of the foregoing description 1 modulation in another group, make each composition in the dipping solution remain in solid substrate.
Then, the solid substrate that maintains each composition is blown 1 hour 80 ℃ of hot blast, thereby make its drying, 2 groups of solid substrates are mixed equably, make granular anti-bacterial material.
When in the granular anti-bacterial material of making, dripping 1 quality % amidin, drip the position and present bright-coloured bluish violet, confirm that so-called starch-iodine reaction carries out.The colour generation that this starch-iodine reaction caused can not disappear at short notice, can keep about a few hours.
As known from the above, among the granular anti-bacterial material both sides of the sheet anti-bacterial material of embodiment 1 and embodiment 2, by generating I with contacting of moisture
3 -, I
5 -, and then the effect of iodine can continue for a long time.Therefore, this shows that anti-bacterial material of the present invention when contacting with pollutant, can bring into play antibacterial action.
In addition, the application is based on the Japanese patent application of on May 19th, 2005 application 2005-146972 number, and its disclosure is as with reference to all being cited.
Claims (24)
1. anti-bacterial composition, it contains iodine based compound (A), iodine is oxidant (B) and acid compound (C), and described iodine based compound (A) and described iodine are that the mass ratio of the content of oxidant (B) is (B)/(A)=1～1000.
2. anti-bacterial composition according to claim 1, the content of described iodine based compound (A) is 0.001～10 quality % with respect to the total amount of composition.
3. anti-bacterial composition according to claim 1 and 2, described iodine based compound (A) is an iodide salt.
4. according to each described anti-bacterial composition of claim 1～3, described iodine is that oxidant (B) is hypoiodite, iodate or periodate.
5. according to each described anti-bacterial composition of claim 1～4, it also contains the compound that can form complex with iodine.
6. anti-bacterial composition according to claim 5, the described compound that can form complex with iodine is a cyclodextrin.
7. anti-bacterial composition according to claim 6, described cyclodextrin connect the form that cyclodextrin-iodine bag that iodine forms connects compound with bag and are contained.
8. according to each described anti-bacterial composition of claim 1～7, it also contains water.
9. anti-bacterial material, it contains
Solid substrate and
Remaining in the inside of described solid substrate or iodine based compound (A), the iodine on surface is oxidant (B) and acid compound (C),
Described iodine based compound (A) and described iodine are that the mass ratio of the content of oxidant (B) is (B)/(A)=1～1000.
10. anti-bacterial material according to claim 9, the content of described iodine based compound (A) is 0.0000 1～20 quality % with respect to the total amount of anti-bacterial material.
11. according to claim 9 or 10 described anti-bacterial materials, described iodine based compound (A) is an iodide salt.
12. according to each described anti-bacterial material of claim 9～11, described iodine is that oxidant (B) is hypoiodite, iodate or periodate.
13., can further be held in described solid substrate with the compound that iodine forms complex according to each described anti-bacterial material of claim 9～12.
14. anti-bacterial material according to claim 13, the described compound that can form complex with iodine is a cyclodextrin.
15. anti-bacterial material according to claim 14, described cyclodextrin connects the form that cyclodextrin-iodine bag that iodine forms connects compound with bag and is held in described solid substrate.
16. according to each described anti-bacterial material of claim 9～15, the material that constitutes described solid substrate is paper, fabric or nonwoven.
17. according to each described anti-bacterial material of claim 9～16, described solid substrate is sheet base material or particulate substrates.
18. according to each described anti-bacterial material of claim 9～17, described iodine based compound (A) is that oxidant (B) is held in solid substrate separately with described iodine.
19. according to each described anti-bacterial material of claim 9～18, described acid compound (C) is held in and maintains the solid substrate that described iodine is oxidant (B).
20. anti-bacterial material according to claim 19, it will keep the 1st sheet material that described iodine based compound (A) forms and keep described iodine at the 2nd sheet base material at the 1st sheet base material is that the 2nd sheet material lamination that oxidant (B) and described acid compound (C) form forms.
21. anti-bacterial material according to claim 19, it will keep the 1st bulk material that described iodine based compound (A) forms and keep described iodine in the 2nd particulate substrates in the 1st particulate substrates is that the 2nd bulk material that oxidant (B) and described acid compound (C) form mixes.
22. lay-up is used, dipping is used, filtration is used, wiping is used, spraying is used or the antibacterial agent of filling usefulness, it contains each described anti-bacterial composition of claim 1～8 or each described anti-bacterial material of claim 9～21.
23. the manufacture method of sheet anti-bacterial material, it has following operation:
Dipping the 1st sheet base material in the solution that dissolving iodine based compound (A) forms in solvent is to keep the operation of described iodine based compound (A) at described the 1st sheet base material;
Dissolving iodine is to flood the 2nd sheet base material in the solution that forms of oxidant (B) and acid compound (C) in solvent, is the operation of oxidant (B) and described acid compound (C) to keep described iodine at described the 2nd sheet base material;
The operation of dry described the 1st sheet base material and described the 2nd sheet base material;
The operation of described the 1st sheet base material of lamination and described the 2nd sheet base material.
24. the manufacture method of granular anti-bacterial material, it has following operation:
Dipping the 1st particulate substrates in the solution that dissolving iodine based compound (A) forms in solvent is to keep the operation of described iodine based compound (A) in described the 1st particulate substrates;
Dissolving iodine is to flood the 2nd particulate substrates in the solution that forms of oxidant (B) and acid compound (C) in solvent, is the operation of oxidant (B) and described acid compound (C) to keep described iodine in described the 2nd particulate substrates;
The operation of dry described the 1st particulate substrates and described the 2nd particulate substrates;
The operation of described the 1st particulate substrates of lamination and described the 2nd particulate substrates.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP146972/2005 | 2005-05-19 | ||
| JP2005146972 | 2005-05-19 | ||
| PCT/JP2006/310048 WO2006123784A1 (en) | 2005-05-19 | 2006-05-19 | Anti-bacterial composition and anti-bacterial material |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101175405A true CN101175405A (en) | 2008-05-07 |
| CN101175405B CN101175405B (en) | 2012-08-15 |
Family
ID=37431353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006800171526A Expired - Fee Related CN101175405B (en) | 2005-05-19 | 2006-05-19 | Anti-bacterial composition and anti-bacterial material |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPWO2006123784A1 (en) |
| CN (1) | CN101175405B (en) |
| TW (1) | TW200640369A (en) |
| WO (1) | WO2006123784A1 (en) |
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| CN102617225A (en) * | 2012-03-12 | 2012-08-01 | 河北科技大学 | Agricultural inorganic sterilization composition and preparation method of agricultural inorganic sterilization composition |
| CN111632192A (en) * | 2020-06-19 | 2020-09-08 | 浙江大学 | Iodine-carrying titanium alloy implant with antibacterial, osteogenic differentiation promoting and mineralization functions and preparation method thereof |
| CN113056321A (en) * | 2018-11-22 | 2021-06-29 | 日挥通用株式会社 | Filter medium for air filter and method for producing filter medium for air filter |
| CN114917267A (en) * | 2022-04-25 | 2022-08-19 | 杭州西子卫生消毒药械有限公司 | Iodine-containing disinfectant for skin and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5782736B2 (en) | 2010-03-16 | 2015-09-24 | 株式会社リコー | Thermal recording medium |
| JP2022039918A (en) * | 2020-08-27 | 2022-03-10 | 株式会社都ローラー工業 | Inactivation agent, inactivation agent adhering substrate, inactivation method, inactivation device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02110A (en) * | 1987-10-02 | 1990-01-05 | Sanyo Chem Ind Ltd | Solid iodophor preparation |
| JPH01290608A (en) * | 1988-05-18 | 1989-11-22 | Sunstar Inc | Germicidal composition |
| JP2005065965A (en) * | 2003-08-22 | 2005-03-17 | Kao Corp | Deodorant composition |
-
2006
- 2006-05-19 TW TW095117881A patent/TW200640369A/en not_active IP Right Cessation
- 2006-05-19 WO PCT/JP2006/310048 patent/WO2006123784A1/en active Application Filing
- 2006-05-19 JP JP2007516353A patent/JPWO2006123784A1/en active Pending
- 2006-05-19 CN CN2006800171526A patent/CN101175405B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102617225A (en) * | 2012-03-12 | 2012-08-01 | 河北科技大学 | Agricultural inorganic sterilization composition and preparation method of agricultural inorganic sterilization composition |
| CN113056321A (en) * | 2018-11-22 | 2021-06-29 | 日挥通用株式会社 | Filter medium for air filter and method for producing filter medium for air filter |
| US12128339B2 (en) | 2018-11-22 | 2024-10-29 | Nikki-Universal Co., Ltd. | Filtering material for air filters and method for manufacturing filtering material for air filters |
| CN111632192A (en) * | 2020-06-19 | 2020-09-08 | 浙江大学 | Iodine-carrying titanium alloy implant with antibacterial, osteogenic differentiation promoting and mineralization functions and preparation method thereof |
| CN114917267A (en) * | 2022-04-25 | 2022-08-19 | 杭州西子卫生消毒药械有限公司 | Iodine-containing disinfectant for skin and preparation method thereof |
| CN114917267B (en) * | 2022-04-25 | 2023-04-11 | 杭州西子卫生消毒药械有限公司 | Iodine-containing disinfectant for skin and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| TWI365042B (en) | 2012-06-01 |
| TW200640369A (en) | 2006-12-01 |
| CN101175405B (en) | 2012-08-15 |
| JPWO2006123784A1 (en) | 2008-12-25 |
| WO2006123784A1 (en) | 2006-11-23 |
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