CN101172190B - Multiplexing method of planning data of ultrasonic therapy system - Google Patents
Multiplexing method of planning data of ultrasonic therapy system Download PDFInfo
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- CN101172190B CN101172190B CN200710124327XA CN200710124327A CN101172190B CN 101172190 B CN101172190 B CN 101172190B CN 200710124327X A CN200710124327X A CN 200710124327XA CN 200710124327 A CN200710124327 A CN 200710124327A CN 101172190 B CN101172190 B CN 101172190B
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Abstract
The invention discloses a multiplexing method of planning data of an ultrasonic therapy system, which comprises the following steps: a1, recording the current planning data when the treatment planning is carried out; a2, when the position of the focus is changed relative to the initial position of the probe, judging whether the planning data is multiplexed or not after the image data is collected, if so, executing the step A3, otherwise, executing the step A4; a3, multiplexing the planning data to plan the treatment; a4, re-determining the lesion area, setting the target distribution parameters and carrying out target distribution. The multiplexing method of the planning data of the ultrasonic therapy system realizes the multiplexing of the planning data, thereby reducing the workload and the operation complexity of doctors and shortening the treatment time of patients.
Description
Technical field
The present invention relates to the ultrasonic therapeutic technical field, be specifically related to a kind of multiplexing method of layout data of supersonic therapeutic system.
Background technology
Medical research finds that the thermostability of tumor cell is than normal cell difference.Under the temperature environment more than 42.5 ℃, inner tumour cell death in 30 minutes, and normal cell damages light and can reverse.The HIFU therapy system is exactly these characteristics according to tumor cell, with the ultrasound wave is energy source, but utilize its penetrance and aggregation, the ultrasound wave that the average sound intensity that the treatment hair is penetrated is lower passes through medium (water behind the air is removed in general employing) coupling, enter body tumor tissue through skin, assemble or converge to a spatial point, form an average sound intensity at 1000W/m
2Above burnt territory (burnt territory size: an ellipsoid zone that is generally 3mm * 3mm * 8mm), making this Jiao territory instantaneous (0.1 second to 5 seconds) produce intensive temperature raises (being higher than 70 ℃), add its cavitation (promptly strong ultrasonic similar vaporific bubble that in liquid, produces, its formation and disappearance can produce high temperature and pressure, thereby make tissue be subjected to heavy damage) and the mechanical oscillation effect, the tissue of destruction Jiao Yuchu.By tumor being carried out so to face,, thereby making the intracellular protein of area for treatment occur coagulation necrosis rapidly by line, produce the effect of treatment by the treatment of face to body point by point scanning by putting line.
Along with the development of ultrasonic therapeutic technology, imaging devices such as ultrasonic combined B ultrasonic device detect the treatment tumor and have also obtained significant progress.In existing ultrasonic therapeutic process, usually all can be with a cover position fixture on the fixing certain location on one's sick bed of patient.And then the tumor before treating is positioned and observes, and gather corresponding lesion image with imaging devices such as B ultrasonic.As shown in Figure 1, B ultrasonic scanning obtains focus 41 before the image acquisition, after the image acquisition, carries out layering and handles back formation figure layer 31.As shown in Figure 2, on gather good image (figure layer 31), carry out cropping cloth target, define the position and the energy parameter that each point are carried out ultrasonic therapy, fill the focus zone 21 that needs emitting treatment with target spot 11, focus zone 21 is approximate ranges of the focus sketched the contours of of doctor." target spot " is the size in institute coking territory after a ultrasonic emitting focuses on." image-region " then is meant the B ultrasonic image that collects on " figure layer ".Repeat the process of this cloth target, finish up to the whole cropping cloth of the figure layer target that all are gathered.Treat at last according to the planning emission ultrasound wave that configures, during treatment, system in layer read data.At first take out a figure layer, obtain the position of a target spot then, in three dimensions, move the treatment head to the position that target spot configures.The energy emission ultrasound wave of setting during then according to planning is finished the treatment of a target spot.Repeat above process, finish whole therapeutic scheme.And in this whole therapeutic process, patient's position is that requirement remains on an immobilized state always, and the point that could guarantee emission is consistent with the three-dimensional position of the point that planning the time is arranged.
Shown in Fig. 3 prior art therapeutic process flow chart, we can very clearly see, in therapeutic process, if patient has produced moving of position.After having retightened patient's position, then whole original treatment planning will be upset, because patient's position is treated an initial position relatively variation has been arranged, so original planning just can not continue to use.At this moment will carry out the process of image acquisition and cropping cloth target again.In the process of cropping cloth target, carry out the cropping of a focus again, the layout of target spot, the setting of energy parameter, and this operation is suitable wasting time and energy, and is the equal of that whole therapeutic process just gives me change.And, owing to the reason that moves, system can not identify the zone of having treated, the doctor has only according to previous impression for the zone of having treated and the experience of observing is again judged, may cause same zone to launch several times ultrasound wave repeatedly treats, cause treatment excessive,, so just have very big potential safety hazard to such an extent as to be damaged to normal tissue.And the zone that has, not treatment, but the doctor feels and may treat, and do not treat once more, just can not effectively kill pathological tissues, do not reach therapeutic effect.
The shortcoming of technology is exactly that the doctor must be patient's cloth target again when the situation that patient moves takes place now.At first to get back to the stage of focus scanning, redefine the starting point and the terminating point of scanning.And then planning again, each figure layer all will be operated again, has increased doctor's workload and complicated operation degree, has increased patient's treatment time.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of multiplexing method of layout data of supersonic therapeutic system, overcomes prior art when carrying out ultrasonic therapeutic, when patient's position relative to treating after head moves, must plan the defective of cloth target again.
The present invention solves the problems of the technologies described above the technical scheme that is adopted to be:
A kind of multiplexing method of layout data of supersonic therapeutic system comprises step:
A1, treating when planning, write down current layout data;
A2, when focus produces change in location with respect to the probe initial position, after acquisition of image data, judge whether multiplexing described layout data, if, execution in step A3 then, if not, execution in step A4 then;
A3, multiplexing described layout data are treated planning;
A4, redefine the focus zone, cloth target parameter is set, carries out the cloth target.
Described treatment planning comprises to be determined the focus zone, cloth target parameter is set, carries out step such as cloth target.
Described layout data comprises focal zone numeric field data, cloth target mode, energy grade, figure layer numbering and cloth target parameter.
Also comprise step after the described steps A 3: judge whether ordering parameter, if then adjust focal zone numeric field data or cloth target parameter.
Also comprise step after the described steps A 4: judge whether ordering parameter, if then adjust focal zone numeric field data or cloth target parameter.
Comprise step before the described steps A 3: the figure layer of selecting multiplexing described layout data.
Described layout data deposits in the data of database table.
Set up a data structure, use described data structure that described layout data is imported in the data of database table.
Multiplexing described layout data comprises step:
The value of the relevant field in B1, the renewal figure layer data table;
B2, find the focal zone numeric field data of focal zone numeric field data table according to described figure layer data table data;
B3, find the target spot arrangement parameter according to described focal zone numeric field data table data;
B4, repaint focus zone and all target spots;
B5, data in the novel targets tables of data more.
Beneficial effect of the present invention is: because the multiplexing method of the layout data of supersonic therapeutic system of the present invention has been realized the multiplexing of layout data, therefore reduced doctor's workload and complicated operation degree, shortened patient's treatment time.
Description of drawings
Fig. 1 is prior art focus and figure layer sketch map;
Fig. 2 fills a certain figure layer focus area schematic that needs emitting treatment for prior art with target spot;
Fig. 3 is a prior art ultrasonic therapeutic process flow diagram flow chart;
Fig. 4 is the multiplexing layout data flow chart of the present invention;
Fig. 5 is a tables of data corresponding relation sketch map of the present invention;
Fig. 6 is the present invention's first cloth target mode sketch map;
Fig. 7 is the present invention's second cloth target mode sketch map;
Fig. 8 is the present invention's the 3rd cloth target mode sketch map;
Fig. 9 is the present invention's the 4th cloth target mode sketch map;
Figure 10 is the multiplexing layout data database manipulation of a present invention flow chart;
Figure 11 is the cloth target design sketch after the multiplexing layout data of the present invention.
The specific embodiment
With embodiment the present invention is described in further detail with reference to the accompanying drawings below:
As shown in Figure 4, the treatment flow chart of comparison diagram 3 can see after image acquisition was finished, system can point out the user whether to select to want the multiplexing layout data that has had.When not selecting when multiplexing, the step of execution also is with original the same.When having selected then can be multiplexed into all data on the newly-generated All Layers when multiplexing, skipped the step of 2-4, directly carry out the 8th step.And be all figure layers to be carried out multiplexing, other figure layer does not need the doctor to carry out manual planning more yet, has saved the time and the step of operation greatly, has liberated the doctor.
The principle of multiplexing realization is that when the doctor treated planning, system noted current cloth target mode, energy grade, figure layer numbering and cloth target region parameter automatically.On new figure layer, regenerate corresponding cropping zone with above-mentioned data parameters, and fill with target spot.In therapy system, a patient may do repeatedly and check, his each inspection numbering of doing is a unique value, and we come unique identification to go out a patient with it.Carrying out data when multiplexing, need in planning process, preserve data, when multiplexing, take out corresponding data again.For this reason system design relevant tables of data be used to preserve data, the tables of data corresponding relation is as shown in Figure 5.
When " image acquisition ", we construct tables of data T_Images and write down corresponding figure layer region parameter in system, and list structure is as follows:
| Field name | Implication |
| Identifier | Major key ID (generating automatically) |
| Study_Id | Check ID |
| Image_No | The figure layer numbering (number of natural sequence number |
| Word) | |
| Image_GUID | Used numbering when getting graph data |
| CureDevice_X | A treatment X position |
| CureDevice_Y | A treatment Y position |
| Field name | Implication |
| CureDevice_Z | A treatment Z position |
| Bdevice_Pos | The Ultrasonic-B probe position |
When gathering, system at first is saved in the image that collects (image can be stored as the BMP image of standard) in the hard disk.And calculate the GUID of one 64 place value, Image_GUID field and the image path by tables of data carries out related, can take out corresponding graphic data by the Image_GUID field of tables of data in the future.The position of treatment head (CureDevice_X, CureDevice_Y, when CureDevice_Z) being illustrated in the image of getting when anterior layer, the three-dimensional space position of treatment head.Ultrasonic-B probe position (Bdevice_Pos) is illustrated in when obtaining this tomographic image, and Ultrasonic-B probe is with respect to the distance that dead-center position rose of treatment probe.Writing down these positions is for after carrying out ensuing planning, can calculate the absolute position of target spot with respect to the position of figure tomographic image with them according to the position of figure layer in the treatment.
After " image acquisition " finished, begin to carry out " focus planning ", this comprises two steps, is exactly the cropping in focus zone and the cloth target in cropping zone.
When " focus cropping ", we construct tables of data T_Ranges and write down corresponding cropping region parameter in system, and list structure is as follows:
| Field name | Implication |
| Identifier | Major key ID (generating automatically) |
| Image_Id | Figure layer ID (from table T_Images) |
| Paint_GUID | The numbering of cropping data |
When we on figure layer, when touching off the focus zone by dragging of mouse, there are the data that cropping comes out in the data file in system.And calculate the GUID of one 64 place value, related by Paint_GUID field in the tables of data with the path of data file (data file can be the data format of the vector graphics of standard).Can find corresponding vector data file by the Paint_GUID field of T_Ranges table after the system, and again vectogram is plotted in corresponding screen position, its position is a relative position with respect to the figure layer.
After " focus collection " more than having carried out and " regional cropping " step, then carry out " the cloth target in cropping zone ".Before generating target spot, system will define the rule of cloth target, just the generation parameter of target spot.We construct tables of data T_TargetParams and write down corresponding cloth target parameter in system, list structure is as follows:
| Field name | Implication |
| Identifier | Major key ID (generating automatically) |
| Range_Id | Area I D (from T_Ranges) |
| Field name | Implication |
| Target_HSpace | The horizontal value in target spot gap |
| Target_VSpace | Vertical value in target spot gap |
| Target_Mode | Cloth target mode |
| Power_Level | Energy grade |
The target spot gap is meant that when carrying out the arrangement of cloth target, between two target spots, relative distance value comprises horizontal and vertical.The meaning of cloth target mode is meant in specified zone target spot by a kind of which type of rule generates and fills.Cloth target mode has four kinds, is respectively cloth target in the focus zone as shown in Figure 6, as shown in Figure 7 along cropping zone inscribe cloth target, as shown in Figure 8 along cropping edges of regions central point cloth target, as shown in Figure 9 along the circumscribed cloth target in cropping zone.
After the parameter that sets the cloth target, system begins to generate the target spot data.We construct tables of data T_Targets and carry out record in system, list structure is as follows:
| Field name | Implication |
| Identifier | Major key ID (generating automatically) |
| Range_Id | Area I D (from T_Ranges) |
| Target_No | Target spot numbering (numeral of natural sequence number) |
| CureDevice_X | A treatment X position |
| CureDevice_Y | A treatment Y position |
| CureDevice_Z | A treatment Z position |
| IsCured | Whether carried out treatment (0 not, the 1st) |
| Power_Level | Energy grade (from T_PowerLevels) |
| Puls_Cycle | Pulse period |
| Field name | Implication |
| Voltage | Emission voltage |
| Shoot_Mode | Radiation pattern |
| Shoot_Time | Expose to the sun the time of penetrating |
Wherein (CureDevice_X, CureDevice_Y are to calculate by the relative position with the figure layer CureDevice_Z) to the three-dimensional position of treatment head, and what preserve in the data base is a relative position at the upper left corner image of current layer.Power_Level is the Grade numbers numeral of an integer, if be zero, then represent the user after generation, adjusted current target spot parameter (Puls_Cycle, Voltage by hand once more, Shoot_Mode, Shoot_Time), then when treatment, read current corresponding target spot parameter (Puls_Cycle, Voltage, Shoot_Mode, Shoot_Time).If Power_Level is non-vanishing, the expression user does not have the manual setting relevant parameters, then read the Power_Level value record identical in the T_PowerLevels table with current Power_Level field value, obtain corresponding target spot parameter (Puls_Cycle, Voltage, Shoot_Mode, Shoot_Time).
Energy grade has comprised the concrete parameter of wanting ultrasonic waves transmitted, and the parameter of a concrete energy grade is fixed in system, carries out record so we construct tables of data T_PowerLevels in system, data structure such as following table:
| Field name | Implication |
| Identifier | Major key ID (generating automatically) |
| Power_Level | Energy grade |
| Puls_Cycle | Pulse period |
| Voltage | Emission voltage |
| Shoot_Mode | Radiation pattern |
| Shoot_Time | Expose to the sun the time of penetrating |
After having finished above data preservation, also just finished the process of image acquisition and focus planning, preserved primary basic data for later data are multiplexing, this moment is with regard in the formal link that has entered treatment.
In the process of treatment, the doctor mainly is responsible for operation ultrasonic therapeutic software.In the treatment, if treated a target spot, then the value of the field IsCured among the updated data table T_Targets is understood by system.Behind all target spots of having treated a figure layer, system reads the target spot data of next figure layer automatically and treats (according to the rule of figure layer numbering, the doctor also can carry out manual selection).In the therapeutic room, can be equipped with the nursing staff of a specialty, because patient is in therapeutic process, can insert some auxiliary monitoring instruments (as the brain wave monitor etc.), the nursing staff is exactly to observe in therapeutic process except monitoring these equipment in addition, and whether patient's position has taken place to move.Because before treatment, generally be to anaesthetize and add the position fixture to patient.And in this therapeutic process, may be for a certain reason (crossed as the anesthesia drug effect etc.) to such an extent as to the variation (as stand up or move etc.) of position has taken place in patient.At this time, the nursing staff will notify the doctor that the situation that this position changes has taken place.The doctor stops current therapeutic process, is patient's fixation postures then again.The doctor gets back to the step of " focus collection " then, gathers patient's image again.After collection is finished, when the user selects a figure layer to prepare to carry out cropping and cloth target once more, system searching is to there being cloth to cross the figure layer of target originally, so it is multiplexing to point out the user whether to carry out data, when the user selects when multiplexing, program is carried out a series of algorithm, and original cropping and cloth target data are multiplexed on the current layer, and the multiplexing flow process of data as shown in figure 10.Repeat above process, till the layout data before all multiplexing all figure layers.Wherein, in the process of novel targets table (T_Targets) more, can multiplexingly whether carry out the sign (being to carry out multiplexing) of treatment according to the principle of target spot numbering.If it is many that new target spot has, then Duo sign is made as not treatment.Target spot table (T_Targets) is except Range_Id and IsCured field, and other field data all will be rewritten again.If it is multiplexing that the user does not select, then delete the data (except the T_PowerLevels) of above-mentioned all tables relevant with figure layer numbering, regenerate again.On the basis that has generated cropping zone and target spot, but the same sample selection of doctor is carried out manual setting to one target spot, or adjusts the position in whole cropping zone.During adjustment, the target position in the zone can produce the identical variation of relative position, and upgrades the related data in T_Ranges and the T_Targets table simultaneously.
In multiplexing intact data and when treating once more, therapeutic process with multiplexing before the same, the target spot of having treated just, system can skip automatically and not carry out treating.The doctor is if treat separately the target spot of having treated.In treatment, can select manual mode, select a target spot, again treatment.
In image acquisition process, after having gathered piece image, we set up in program, and such data structure is used for and data base's swap data:
struct T_IMAGES
{
int Study_Id；
int Image_No；
char Image_GUID[64]；
double CureDevice_X；
double CureDevice_Y；
double CureDevice_Z；
double Bdevice_Pos；
}；
Example pseudo-code is as follows:
int main()
{
T_IMAGES images_data；
images_data.Study_Id＝1；
images_data.Image_No＝1；
images_data.Image_GUID＝″{0038-3837-3938-940C-3939-83C3}″；
images_data.CureDevice_X＝2.3；
images_data.CureDevice_Y＝2.5；
images_data.CureDevice_Z＝3.0；
images_data.Bdevice_Pos＝0.5；
// at last data structure as a new record, be inserted into the table T_Images in.
TDataSet DataSet＝new DataSet()；
DataSet.Insert()；
DataSet.Post()；
}
We copy the Programming Methodology of image acquisition, and the data of doctor's cropping are deposited in the T_Ranges table, and the cloth target parameter that is provided with is deposited in the T_TargetParams table, and the target spot data of filling in the zone are deposited in the T_Targets table.In this example, suppose to have carried out the planning of focus.Suppose to have the image of N shell, the tomographic image that we choose wherein describes, and wherein for target spot, different energy grades has different color depths and represents.The cloth target effect of figure layer 1 as shown in figure 11.
The doctor has selected " begin treatment " function in program after, the treatment head moved to a target spot (CureDevice_X of the target spot that reads before this from database table T_Targets, CureDevice_Y, the value of CureDevice_Z, position by these three values adds that the relative position of figure layer decides) the position, pass the parameter (being exactly the relevant parameter of energy grade) of treatment then down, launch ultrasound wave then and treat from the value of the Power_Level among the table T_Targets.Treat what a target spot, move to next target spot, move in circles, finish up to the whole treatment of this figure layer.Read in next figure layer then, carry out identical operations.In the therapeutic process, move if patient has produced, then the doctor at first clicks " stopping treatment " button in the treatment interface, ends current therapeutic process.This moment, the doctor was fixed up patient's position again, again the process of carries out image collection.After collection is finished, carry out the function of planning cloth target.At this moment, whether system can search for has had cloth to cross target originally, if having, expression has the data can be multiplexing, points out, and multiplexing if the doctor has selected to carry out, at this moment, system reads data from tables of data, is applied to current figure layer and comes up.
Those skilled in the art do not break away from essence of the present invention and spirit, can there be the various deformation scheme to realize the present invention, the above only is the preferable feasible embodiment of the present invention, be not so limit to interest field of the present invention, the equivalent structure that all utilizations description of the present invention and accompanying drawing content are done changes, and all is contained within the interest field of the present invention.
Claims (9)
1. the multiplexing method of the layout data of a supersonic therapeutic system is characterized in that, comprises step:
A1, treating when planning, write down current layout data;
A2, when focus produces change in location with respect to the probe initial position, after acquisition of image data, judge whether multiplexing described layout data, if, execution in step A3 then, if not, execution in step A4 then;
A3, multiplexing described layout data are treated planning;
A4, redefine the focus zone, cloth target parameter is set, carries out the cloth target.
2. the multiplexing method of the layout data of supersonic therapeutic system according to claim 1 is characterized in that: described treatment planning comprises step: determine the focus zone, cloth target parameter is set, carries out the cloth target.
3. the multiplexing method of the layout data of supersonic therapeutic system according to claim 2 is characterized in that: described layout data comprises focal zone numeric field data, figure layer numbering and a cloth target parameter.
4. the multiplexing method of the layout data of supersonic therapeutic system according to claim 2 is characterized in that: also comprise step after the described steps A 3: judge whether ordering parameter, if then adjust focal zone numeric field data or cloth target parameter.
5. the multiplexing method of the layout data of supersonic therapeutic system according to claim 2 is characterized in that: also comprise step after the described steps A 4: judge whether ordering parameter, if then adjust focal zone numeric field data or cloth target parameter.
6. the multiplexing method of the layout data of supersonic therapeutic system according to claim 4 is characterized in that: comprise step before the described steps A 3: the figure layer of selecting multiplexing described layout data.
7. the multiplexing method of the layout data of supersonic therapeutic system according to claim 6, it is characterized in that: described layout data deposits in the data of database table.
8. the multiplexing method of the layout data of supersonic therapeutic system according to claim 7 is characterized in that: set up a data structure, use described data structure that described layout data is imported in the data of database table.
9. the multiplexing method of the layout data of supersonic therapeutic system according to claim 8, it is characterized in that: multiplexing described layout data comprises step:
The value of the relevant field in B1, the renewal figure layer data table;
B2, find the focal zone numeric field data of focal zone numeric field data table according to described figure layer data table data;
B3, find the target spot arrangement parameter according to described focal zone numeric field data table data;
B4, repaint focus zone and all target spots;
B5, data in the novel targets tables of data more.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1803224A (en) * | 2005-01-10 | 2006-07-19 | 重庆海扶(Hifu)技术有限公司 | High intensity focused ultrasound therapy device and method |
| CN1809399A (en) * | 2003-04-17 | 2006-07-26 | 布赖汉姆妇女医院 | Shear mode therapeutic ultrasound |
| CN1997913A (en) * | 2004-06-29 | 2007-07-11 | 皇家飞利浦电子股份有限公司 | Method and device for medical ultrasound diagnosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1809399A (en) * | 2003-04-17 | 2006-07-26 | 布赖汉姆妇女医院 | Shear mode therapeutic ultrasound |
| CN1997913A (en) * | 2004-06-29 | 2007-07-11 | 皇家飞利浦电子股份有限公司 | Method and device for medical ultrasound diagnosis |
| CN1803224A (en) * | 2005-01-10 | 2006-07-19 | 重庆海扶(Hifu)技术有限公司 | High intensity focused ultrasound therapy device and method |
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