CN101137339A - Improved construction of an intraocular artificial lens - Google Patents

Improved construction of an intraocular artificial lens Download PDF

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Publication number
CN101137339A
CN101137339A CN200680007371.6A CN200680007371A CN101137339A CN 101137339 A CN101137339 A CN 101137339A CN 200680007371 A CN200680007371 A CN 200680007371A CN 101137339 A CN101137339 A CN 101137339A
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CN
China
Prior art keywords
optical element
artificial lens
intra ocular
ocular artificial
capsule bag
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Granted
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CN200680007371.6A
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Chinese (zh)
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CN101137339B (en
Inventor
米希尔·克里蒂安·龙巴赫
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Akkolens International BV
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Akkolens International BV
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Priority claimed from NL1029041A external-priority patent/NL1029041C1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648Multipart lenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1616Pseudo-accommodative, e.g. multifocal or enabling monovision
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1632Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing radial position, i.e. perpendicularly to the visual axis when implanted

Abstract

Intraocular artificial lens of variable optical power comprises two optical elements which are shiftable mutually perpendicular to the optical axis, and have such a shape that they exhibit, in combination, different optical powers at different positions; positioning mechanism for positioning the optical elements in the eye; and driving mechanism for driving optical element(s) for executing a movement relatively to the other optical element. The positioning mechanisms are adapted to urge the optical elements to a resting position when the driving mechanisms are inactive. An independent claim is also included for method for manufacturing an intraocular artificial lens comprising at least two optical elements and positioning mechanism to position the optical elements in a capsular bag, comprising connecting both optical elements to the positioning mechanism prior to implantation in the capsular bag.

Description

The improvement structure of intra ocular artificial lens
Technical field
The present invention relates to a kind of variable dioptric intra ocular artificial lens that has, it comprises two optical elements, positioner and driving devices, two optical elements can move mutually along the direction perpendicular to optical axis, wherein the shape of optical element makes them have different diopters in the mode of combination at different relative positions, positioner is used for optical element is positioned in the eyes, and driving device is used to drive one of them optical element at least to realize the motion with respect to another optical element.
Background technology
This intra-ocular lens was also described in Netherlands patent applications 1025622.
Present patent application is described the application principle of two optical elements, and described two optical elements can move mutually along the direction perpendicular to optical axis in the intra ocular artificial lens.The application comprises after the removal natural lens, several basic measures of locating in the capsule bag, fixing and driving this intra ocular artificial lens.Natural ciliary muscle by eyes drives, and optical element can relative to each other move, to obtain to regulate (accommodative) function.
Ciliary muscle has formed the capsulociliary part of eyes, and corpus ciliare just in time is positioned at after the iris of eyes, before the vitreous body.Put at the stop bit of having a rest, the ciliary muscle diameter is bigger, and diameter diminishes when shrinking.Ciliary muscle drives regulatory function.The capsule bag is positioned at ciliary muscle, and the crystalline lens with nature flexibility of eyes is arranged in the capsule bag.The capsule bag is connected to ciliary muscle by the ciliary zonule (zonulea) that radially extends basically.
Use natural lens, regulating naturally of eyes is as follows.When seeing at a distance, ciliary muscles relax and diameter are bigger.Thereby the ciliary zonule of tension capsule bag is subjected to pulling force, makes crystalline lens more flat.Ciliary muscle can be seen at a distance in the raw.When seeing at a distance, ciliary muscle contraction becomes diameter less.Zonulae relax, natural lens return to the more recessed shape of its nature.
Summary of the invention
The purpose of this invention is to provide a kind of intra ocular artificial lens, wherein try one's best near the natural regulatory function of eyes.
Because positioner is suitable for that optical element is forced to the stop bit of having a rest and puts, this purpose is achieved.Thereby, formed just like the same structure of natural lens, wherein there be not external force to be applied under the situation on the artificial lens construction, it returns to the stop bit of having a rest on the whole and puts.
According to first embodiment, optical element is suitable for returning to and has the dioptric stop bit of having a rest that is used to see nearby and put.This is to see modal situation nearby in our present society, for example, reads or browse computer screen.
In alternate embodiments, optical element is suitable for returning to having and is used to see that the dioptric stop bit of having a rest at a distance puts.In this embodiment, when being adjusted to close-ups, element moves away from the stop bit of having a rest and puts.
Two kinds of embodiments have all used the structure that drives prosthetic lens, and these structures all are similar to the driving mechanism of nature eye lens a little.
Another embodiment provides following measure, that is, positioner is included in the work stop device of (active) of at least one position.These stop devices can be positioned on structural desirable (attractive) position around the intra-ocular lens.Stop device can be located such that element all works at the two ends of working range, thereby they are as limiting the area that optical element is movable through.
Another embodiment provides following measure, that is, positioner is suitable for outwards urging the outward flange of capsule bag, and makes this edge and ciliary muscle Mechanical Contact.The capsule bag is connected to ciliary muscle indirectly by the flexible support ribbons of radially extending.This measure is connected to ciliary muscle with the edge of capsule bag, and therefore, the motion of ciliary muscle is directly changed into the motion of optical element, thereby has obtained more direct being coupled.
Another preferred implementation provides following measure, that is, optical element forms in their overlapping maximum positions to have the low light level and learn dioptric crystalline lens, and forms the crystalline lens with the strongest optical diopter in their overlapping minimum positions.This has been avoided following situation, that is, when iris magnified, quality was observed in the dazzle influence.
Alternate embodiments provides following measure, that is, optical element forms in their overlapping maximum positions to have high light and learn dioptric crystalline lens, and forms the crystalline lens with the most weak optical diopter in their overlapping minimum positions.Utilize the particular design of artificial lens construction, this embodiment has the size that reduces within the eye.
Next embodiment provides following measure, that is, positioner is suitable for the stop bit of having a rest of back adjusting optical element in being implanted to the capsule bag and puts.In the operation process, implant prosthetic lens.Often, owing to can not accurately determine the situation of ophthalmic in advance, so positioner need have some adjustables.Therefore, at intra-operative, can regulate positioner according to situation about finding.Yet, also may after regulate again, for example, lenticular through lasting in user has been experienced the synthetic eye in several weeks.It is viewed not normal period that can correct this section this moment.
By the element that comprises that in positioner size adjustable is whole, it is desirable implementing this embodiment.This adjustable obtains by comprise two parts in element, they can be interconnection at diverse location, for example, can engage pattern (pattern), and the engagement device that is suitable for engaging at diverse location this pattern is provided for other element by providing for one of them parts.Also may utilize the element that can change length by external factor.Its example forms by the element made from certain polymer, and this element carries out further polymerization by energy is provided, and changes its length in this further polymerization process.Another example is just to use so-called memory metal because the energy that appends---should with in be preferably laser, memory metal can change their shape lastingly.Element with this shape can be designed to that its length can change when its alteration of form.
Simple relatively first embodiment provides following measure, promptly, driving device comprises four bars, wherein the first pair of bar is connected to the side of one of them optical element, second pair of bar is connected to the opposite side of another optical element, and one of them of every pair of bar is connected with the first of the same ciliary muscle associated movement of capsule bag, and two other bars of every pair of bar all are connected with second motion parts with the ciliary muscle associated movement, and second motion parts is positioned to relative with first.
Alternate embodiments provides following measure, that is, driving device comprises the element that mainly is rigidly connected, and element one side that is rigidly connected is connected with optical element, and is suitable for being connected with the part of the same ciliary muscle associated movement of capsule bag at opposite side.This measure also provides better simply structure, in addition, provides more direct being coupled between the motion of the part that is connected to ciliary muscle of capsule bag and described optical element.
Obviously, also the element that is rigidly connected may be manufactured firm to making whole parts have propagation function, thereby do not need other guider.This makes the rigid element volume too big.For preventing this situation, desirable (attractive) mode is by link optical element to be connected to the capsule bag at opposite side.
This link can have the configuration of sliding structure or hinge structure.Positioner is comprised flexibly connect element, flexibly connect element and be positioned at the side relative with the element that is rigidly connected, it is connected to optical element and is designed to be able to and is connected with the edge of the same ciliary muscle associated movement of capsule bag.Therefore, obtained lightweight support component, made that structure is very simple and efficient.
As mentioned above, the present invention needs to exist between the part of same ciliary muscle associated movement of link and capsule bag and connects.In order to set up this connection, rigidity and compliant member have fixture, be also referred to as " button loop (haptics) ", its be positioned at each means of attachment to the relative place, side of that side of optical element, and fixture allows to be connected to the part of the same ciliary muscle associated movement of capsule bag.These fixtures can be the integral part of rigidity or flexible attachment components.
Intra-ocular lens must be implanted in operation process.This means that ciliary muscle loosens in implantation process.Intra-ocular lens according to first embodiment is positioned at---because structure is urged the positioner that the stop bit of having a rest is put---stop bit of having a rest and puts.Then, intra-ocular lens has the highest diopter, and driving device shrinks.Within the eye in the prosthetic lens implantation process, between rigidity and the flexible attachment components, may fully not be connected between the edge of fixture and the same ciliary muscle associated movement of capsule bag.Need this connection,, make the normal function of regulating intra-ocular lens become possibility so that link is connected with the part of the same ciliary muscle associated movement of capsule bag.For this contact is provided, another embodiment provides following feature, that is, intra-ocular lens comprises retaining element, retaining element worked in the limited cycle, and can realize contacting between the part of rigidity and flexible attachment components and the same ciliary muscle associated movement of capsule bag.These retaining elements connect the part of the same ciliary muscle associated movement of rigidity and flexible attachment components and capsule bag, thereby these parts have had the possibility that grows together.
Above-mentioned measure needs following situation,, behind the limit cycle of lasting connection growth, does not hinder regulatory function that is.Therefore, another embodiment provides following measure, that is, retaining element is by being made by the dissolved material of the liquid in the eyes.Can suppose that the time long enough of course of dissolution cost grows together with the part of the same ciliary muscle associated movement that allows link and capsule bag.
In another embodiment, comprise Ω shape structure in each flexible attachment components.This Ω shape structure can simply be made by milling or molding process, and calculates, and this shape is very suitable, because the mechanical tension distribution is favourable.This is important, because must prevent the fatigue of material as far as possible.
Preferred implementation of the present invention comprises stop device.Above-mentioned Ω shape structure provides possibility these stop devices to be embodied as the stop teat that is arranged in these Ω shape structures.Comprise that the stop teat is a kind of simple measure.
In alternative constructions, flexible by following measure acquisition, that is, flexible attachment components comprises the longitudinal component of the direction of motion extension that is basically perpendicular to optical element, and it is connected to fixture at two ends, is connected to optical element at medium position.This configuration seems to have desirable mechanical property.
Modern technologies and material provide make thin, according to the probability of intra-ocular lens of the present invention.Yet this has caused following problem, that is, and and the crystalline lens overrelaxation that can become, and optical surface can be applied to its force deformation in adjustment process.Because optical element, this will cause degenerating of crystalline lens optical quality.This measure of reinforcing element by extending around the edge that is provided at optical element can prevent this situation, and by reinforcing element, optical element will obtain required rigidity.
Modern attachment techniques provides following probability, that is, the edge of reinforcement is made by the material different with the material of making optical element.This provides the material of selecting optimum specification to be fit to the measure of specific (special) requirements.
But capsule bag contact optical element that optical element inserted and bonding (stick) or tie (tack) to them or even grow together.This can influence the function of the regulatory function of intra-ocular lens.In order to prevent this situation, fixture is equipped with the cushion block parts that extend along optical axis direction, and the front side of its maintenance capsule bag and rear side and optical element leave.
Specific implementations provides following measure, that is, the shape of fixture makes them be suitable for changing the diameter of capsule bag flexibly.The capsule bag is a dynamic cell; It changes shape and diameter according to the contraction of ciliary muscle or the state that loosens.
Principle of the present invention need be used at least two optical elements.The inventor is well understood to, and these elements can be identical.This says so very favourable on the angle of making.Essential attention, this feature also not only refers to optical element, and refer to be connected to the parts of optical element.
Obviously, two elements must be positioned on two different axis and rotate.Optical element also can have different shapes, and perhaps the regulatory function of one of them optical element can be added on the fixing dioptric crystalline lens, and this fixing dioptric crystalline lens can be corrected the basic dioptric of eyes.Produced different optical elements thereupon.
Flexible connecting member and fixture and rigid connector and fixture can be made with identical materials.This feature provides by same manufacturing process---for example by turning and milling or by molded---produces the chance of all these parts.
Also possible with different material manufacture optical elements and other parts, therefore can be the selection of each function optimization material.
According to selected material, separately make and treat that the element that links together subsequently also is desirable.This embodiment also relates to the method for making intra ocular artificial lens, the positioner that it comprises at least two optical elements and is used for optical element is positioned at the capsule bag, and wherein two optical elements connect before prosthetic lens is implanted the capsule bag.
Desirable, one of them is planted and connects by the mechanical form acquisition that is connected between optical element, flexibility and rigid connector and the fixture.This connection can be made simply, and does not use other device.
This embodiment also relates to a kind of method that is used to make intra ocular artificial lens, it comprises at least two optical elements and optical element is positioned at positioner in the capsule bag that wherein optical element is connected to positioner in the operation process that intra-ocular lens is positioned in the capsule bag.
Also possible is, optical element, flexibility and be rigidly connected between parts and the fixture that one of them is planted to connect and comprises bonding connection.Adherent type must carefully be selected, and makes it not influence lenticular function.
When optical element, flexibility be rigidly connected between parts and the fixture that one of them plants the repeated polymerization effect that connects by material when obtaining, obtained desirable especially embodiment.
Another possibility is, optical element, flexibility and be rigidly connected between parts and the fixture that one of them is planted and connects by being welded to connect acquisition.Laser and ultrasonic technique are the examples of this solder technology.
Also possible is, optical element, flexibility and be rigidly connected between parts and the fixture that one of them is planted to connect and is connected to form by molded.Might use same or different material for different elements and parts.
When using form fit to connect, preferably, connection should be in various relative positions.This provides and has changed the chance of optical element relative position, and the possibility that makes optical specification be suitable for wearer's condition is provided.This process can take place when implanting intra ocular artificial lens.The invention still further relates to and during implanting, determine capsule bag size and the method for work that connects optical element according to described measured value with positioner.
After the implantation, fixture must be fixed to the part of the same ciliary muscle associated movement of capsule bag.The tissue of supposing fixture and capsule bag grows together.Optionally scheme is, for fixture provides coarse or corrugated surface to stimulate this growth course.Coarse and the wrinkling extension letter justice that comprises surface area of term with other shape or other increase pattern.
Be noted that in addition that in order to use feature of the present invention optical element certain distance of must moving is poor to produce enough diopters between end position.It may be exactly this situation that the internal diameter varies of ciliary muscle is not enough to use the present invention.
By using leverage head it off substantially, leverage becomes the little conversion of motion of ciliary muscle the big motion of optical element.
Also may utilize the additional-energy of other form---micromechanics for example, it is included in the blood flow, perhaps in response to the motion of electromotive force or ciliary muscle or eyelid.Ciliary muscle or can be used to control the motion of optical element by the represented direction of visual lines in the position of eyeball or iris.Do not get rid of yet and be used for control or be used for energy---the energy of drive system for example, for example from the energy of light---the out of Memory source.
Description of drawings
To the present invention be described by accompanying drawing below, shown in the figure:
Fig. 1: be used to explain axonometric chart of the present invention;
Fig. 2: along transverse to planar sectional view according to the optical axis of the optical element of the intra ocular artificial lens of first embodiment;
Fig. 3: the sectional view suitable in second embodiment with Fig. 2;
Fig. 4: be parallel to sectional view according to the optical axis of the intra ocular artificial lens of another embodiment;
Fig. 5: the sectional view of another embodiment of intra ocular artificial lens in the another embodiment of the present invention; And
Fig. 7: the sectional view of specific implementations of the present invention.
The specific embodiment
Fig. 1 illustrates the axonometric chart according to intra ocular artificial lens of the present invention, and wherein crystalline lens is whole represents with 1.Crystalline lens comprises two optical elements 2,3, and they all are positioned on the lenticular optical axis 4.The optical signature of crystalline lens 1 changes with moving mutually of optical element.Optical element the 2, the 3rd, separately.From optical angle, these elements can contact, but from angle biology about precipitate on the optical element and possible tiing (tack), this contact is so undesirable.
Last optical element 2 is connected to fixture 6 by the parts 5 that are rigidly connected, intra ocular artificial lens is attached to the capsule bag in---ophthalmic is used for lenticular natural cavity---.Following optical element 3 is connected to fixture 8 by the parts 7 that are rigidly connected. Fixture 6,8 extends in relative position, and they are suitable for being attached to the part of the same ciliary muscle associated movement of capsule bag.
Optical element 2 is connected to the fixture 10 of the element opposite side that is rigidly connected by flexible attachment components 9.And optical element 3 is connected to the fixture 12 of the element opposite side that is rigidly connected by flexible attachment components 11. Fixture 10 and 12 roles are similar to fixture 6 and 8, are respectively applied for supporting optical component 2 and 3.The flexibility of flexible attachment components 9,11 allows optical element 2,3 motions.Because this structure, last optical element 2 will along with the motion of fixture 6 and along with the motion of the connected part of capsule bag associated movement, the capsule bag is then with the ciliary muscle associated movement.Similarly, optical element 3 will be with fixture 8 associated movements.According to this structure, optical element will present mutual linear movement.Also might construct link as follows, that is, make optical element present mutual rotation or aggregate motion.Under the situation of the design that is used for rotational motion, center of rotation can place the outside of optical element.
Can be connected and fixed part in every way to 6,12 and be connected and fixed part to 8,10.Yet keeping these fixtures also is a kind of selection scheme to disconnecting.But all fixtures must be attached to the capsule bag.
Fixture 6,8,10,12 is equipped with extension 13 to produce at interval between capsule bag and optical element.
Point out that at last this figure is a sketch map, be intended to illustrate various elements, their relative position and their function.The shape of various elements can---and inciting somebody to action in most cases---remarkable difference.
Fig. 2 illustrate in greater detail optical element 2 with and the structure of attached parts.This relates in particular to the flexible attachment components 9 that Ω shape parts 15 are housed.The structure of Ω shape parts provides flexibility to a certain degree.Help preventing mechanical stress concentration though Ω shape parts have been shown among the figure, also do not get rid of other shape, for example thread-shaped and spiral type.Compliant member 9 also is equipped with two stopping elements 16,17, and they define the stop bit of having a rest of optical element 2 and 3 respectively and put, but does not get rid of other structure.
Another modification has been shown among Fig. 3, wherein, has replaced Ω shape parts 15, used two this structure 15A and 15B, they all are positioned at same plane.In this structure, possible cross force is cancelled, the therefore only remaining power that vertically acts on along flexible attachment components.
Fig. 4 shows a kind of modification, and wherein optical element 2,3 makes so to approach and makes these elements not have enough rigidity. Optical element 2,3 all is equipped with the support portion 18 of thickening along the edge, to prevent the position of indefiniteness.And the ring portion of Ω shape parts extends in the plane that is parallel to optical axis.And, also may use two ring portions that are positioned at same plane.
Fig. 5 illustrates the alternative method of the optical element that is used to suspend.Ciliary muscle make two diagonally, 20,21 motions of the fixture of relative localization, fixture 20,21 connects by being positioned to rhombohedral four bars 22,23,24,25.Between each bar and the fixture and between the bar 22,23, comprise hinge between the bar 24,25.Two last hinges also are connected respectively to optical element 2,3.The motion of fixture 20,21 will cause the mutual motion of optical element 2 and 3.With preferred embodiment compare, in this embodiment, do not comprise flexible member.Yet, can comprise that stop teat 26,27 puts with the qualification stop bit of having a rest.Can comprise that other stop teat is to limit another extreme position of motion.
Fig. 6 shows in detail the selection scheme that is used for optical element and is rigidly connected the connection between the parts.Wherein the adjusting between two elements 2 and 9 or adaptive be possible.The parts that are rigidly connected comprise a plurality of recesses 28, and recess 28 is suitable for engaging and is attached to a plurality of protruding 29 of optical element.By a large amount of recesses, optical element may be connected different mutual alignments with the parts that are rigidly connected.Mutual alignment when this measure makes two optical elements be in the stop bit of having a rest to put can be able to adaptive, and therefore, makes the diopter of putting at the stop bit of having a rest be able to adaptive.This borrowing executed the stage that provides than the back carries out this adaptive possibility---for example at the lenticular intra-operative in location---.
Fig. 7 illustrates the alternative constructions of flexible attachment components and the fixture that is connected, and wherein only shows an optical element.Link comprises transverse to the localized oval-shaped part 30 of the axis of movement of optical element.This oval link 30 extremely is connected to fixture 12 by coupling part 31,32 at it, and is connected to optical element 2 by bridging part 33.In this embodiment, provide flexible by oval-shaped part 30 and coupling part 31 and 32.Should be pointed out that coupling part 31,32 should be crooked, to obtain the distribution of optimum power.Therefore, by fixture 12, coupling part 31 and 32 and oval link 30 formed shape sealing, that null ellipse is arranged.Stopping element 34,35 can be included in 12,30,31,32 openings that form.These stopping elements provide the function of the retainer 16,17 that is similar to shown in Fig. 2.Obviously, intra-ocular lens according to the present invention comprises two optical elements, the angle of this two mutual Rotate 180s of optical element °, and structure is like that as shown in fig. 1.
Illustrate above, at optical element be rigidly connected and can regulate between the element, but regulatory function also can be incorporated into be rigidly connected between parts and the fixture or optical element and flexibly connect between the element or flexibly connect element and attached fixture between.The combination of all these measures also is a possibility.
Obviously, except the structure that illustrates, have a plurality of recesses and projection, also can use other structure.For example, can add that the part of different length is to replace rigidity or flexible attachment components.
As a rule, obviously, can use the combination of the measure of above-mentioned various embodiments.Under the situation that does not deviate from protection scope of the present invention, also may carry out alienation to described embodiment.

Claims (29)

1. variable dioptric intra ocular artificial lens comprises:
Two optical elements, it can move mutually along the direction perpendicular to optical axis, and wherein, the shape of described optical element makes them have different diopters in the mode of combination at different relative positions,
Positioner, it is used for described optical element is positioned in the eyes,
Driving device, it is used to drive one of them described optical element at least carrying out the motion with respect to another optical element,
It is characterized in that when described driving device inertia, described setting element is suitable for that described optical element is forced to the stop bit of having a rest and puts.
2. intra ocular artificial lens as claimed in claim 1 is characterized in that, described optical element has a rest only described that state has the diopter that is suitable for seeing nearby.
3. intra ocular artificial lens as claimed in claim 1 is characterized in that, described optical element has at the described state of having a rest only and is suitable for seeing diopter at a distance.
4. as claim 1,2 or 3 described intra ocular artificial lens, it is characterized in that during described crystalline lens was implanted described capsule bag, described positioner was designed to force the edge of described capsule bag to contact with described ciliary muscle.
5. each described intra ocular artificial lens in the claim as described above, it is characterized in that, described optical element forms the crystalline lens with the most weak optical diopter in their overlapping maximum positions, and forms the crystalline lens with the strongest optical diopter in their overlapping minimum positions.
6. each described intra ocular artificial lens in the claim as described above, it is characterized in that, described optical element forms the crystalline lens with the strongest optical diopter in their overlapping maximum positions, and forms the crystalline lens with the most weak optical diopter in their overlapping minimum positions.
7. each described intra ocular artificial lens in the claim as described above is characterized in that, described positioner is suitable for adjusting the stop bit of having a rest of described optical element and puts after it implants described capsule bag.
8. intra ocular artificial lens as claimed in claim 7 is characterized in that, described positioner comprises the element that size adjustable is whole.
9. each described intra ocular artificial lens in the claim as described above, it is characterized in that, described driving device comprises two pairs of bars, wherein the first pair of bar is connected to a side of one of them optical element, second pair of bar is connected to the another side of another optical element, and one of them of every pair of bar is connected with the first of the same described ciliary muscle associated movement of described capsule bag, another bar of every pair of bar is connected with the second portion of the same described ciliary muscle associated movement of described capsule bag, and described second portion is relative with the position of described first.
10. as each described intra ocular artificial lens among the claim 1-8, it is characterized in that, described driving device comprises the element that mainly is rigidly connected, and it is connected to described optical element in a side, is suitable for being connected to the part of the same described ciliary muscle associated movement of described capsule bag at opposite side.
11. intra ocular artificial lens as claimed in claim 10 is characterized in that, described optical element is connected to described capsule bag by the link that is positioned at described edge opposite side.
12. intra ocular artificial lens as claimed in claim 11, it is characterized in that, described positioner comprises flexible attachment components, its end relative with the described parts that are rigidly connected at described optical element is connected to described optical element, is suitable for being connected to the part of the same described ciliary muscle associated movement of described capsule bag at the other end.
13. each described intra ocular artificial lens in the claim as described above, it is characterized in that, fixture is equipped with in the side that is positioned to the described rigidity relative with the side that is connected to described optical element respectively and flexibly connects element, and described fixture is used to be connected to the part of the same described ciliary muscle associated movement of described capsule bag.
14. intra ocular artificial lens as claimed in claim 12 is characterized in that, each described flexible attachment components comprises at least one Ω shape structure.
15. intra ocular artificial lens as claimed in claim 14 is characterized in that, described structure comprises the stop teat, and described stop teat is used for the described optical element of stop further moving along one or more directions.
16. intra ocular artificial lens as claimed in claim 12, it is characterized in that, described flexible attachment components comprises that the edge is transverse to the longitudinal component of described optical element direction of motion extension basically, and it is connected to described fixture at two ends, and is connected to described optical element in the centre position.
17. the described intra ocular artificial lens of claim is characterized in that as described above, described optical element is equipped with the reinforcement structure on every side at described edge.
18. intra ocular artificial lens as claimed in claim 17 is characterized in that, described reinforcement structure is made by the material that is different from the material of making described optical element.
19. each described intra ocular artificial lens in the claim is characterized in that as described above, described fixture is equipped with the cushion block that extends along described optical axis direction, and described cushion block is used to keep the distance between described optical element and the described capsule bag.
20. each described intra ocular artificial lens in the claim is characterized in that as described above, described fixture has the flexible shape that is used to adjust to change the diameter of described capsule bag.
21. each described intra ocular artificial lens in the claim is characterized in that as described above, described optical element, described flexible attachment components and the described parts that are rigidly connected are made with identical materials.
22., it is characterized in that described optical element, described flexible connecting device and the described device that is rigidly connected are made with the material that differs from one another as each described intra ocular artificial lens in the claim 1 to 20.
23. the described intra ocular artificial lens of claim is characterized in that as described above, described optical element, described flexible attachment components, described one of them that is rigidly connected between parts and the described fixture are planted to connect and are connected to form by form fit.
24. the described intra ocular artificial lens of claim is characterized in that as described above, described optical element, described flexible attachment components, describedly is rigidly connected between parts and the described fixture that one of them is planted to connect and forms by bonding connection.
25. the described intra ocular artificial lens of claim is characterized in that as described above, described optical element, described flexible attachment components, the described repeated polymerization that one of them kind connects by material between parts and the described fixture that is rigidly connected form.
26. the described intra ocular artificial lens of claim is characterized in that as described above, described optical element, described flexible attachment components, describedly is rigidly connected between parts and the described fixture that one of them is planted to connect and is connected to form by molded.
27. method that is used to make intra ocular artificial lens, it comprises at least two optical elements and described optical element is positioned at positioner in the capsule bag, it is characterized in that described two optical elements all were connected to described positioner in the past at the described capsule bag of implantation.
28. method that is used to make intra ocular artificial lens, it comprises at least two optical elements and described optical element is positioned at positioner in the capsule bag, it is characterized in that described two optical elements all are connected to described positioner during described intra ocular artificial lens is implanted to described capsule bag.
29. as claim 27 or 28 described methods, it is characterized in that, determine the size of described capsule bag during operation, and described optical element be connected about the size that side gets with described positioner.
CN200680007371.6A 2005-03-09 2006-03-09 Improved construction of an intraocular artificial lens Active CN101137339B (en)

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NL1029041A NL1029041C1 (en) 2005-03-09 2005-05-13 Improved construction of an intraocular artificial lens
PCT/NL2006/050050 WO2006118452A1 (en) 2005-03-09 2006-03-09 Improved construction of an intraocular artificial lens

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014106374A1 (en) 2013-05-07 2014-11-13 Akkolens International B.V. Accommodating intraocular lens with sulcus fixation haptics
CN110996847A (en) * 2017-06-27 2020-04-10 爱尔康公司 Injector, intraocular lens system, and related methods
US11406490B2 (en) 2012-01-24 2022-08-09 Alcon Inc. Modular intraocular lens designs and methods

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2711908T3 (en) 2007-10-15 2019-05-08 Akkolens Int B V Adjustable accommodative intraocular lens and positioning means
NL2003881C2 (en) * 2009-11-30 2011-05-31 Akkolens Int Bv Adjustable intraocular lens.
EP2979662A1 (en) 2014-08-01 2016-02-03 Akkolens International B.V. Intraocular lens with electricity generator and additional functional systems

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305294A (en) * 1964-12-03 1967-02-21 Optical Res & Dev Corp Two-element variable-power spherical lens
EP0162573A3 (en) * 1984-04-17 1986-10-15 Sanford D. Hecht Eye implant
US4863468A (en) * 1987-12-04 1989-09-05 Designs For Vision, Inc. Universally adjustable telescopic spectacle assembly for use with implanted intraocular lenses and associated methods
US4994082A (en) * 1988-09-09 1991-02-19 Ophthalmic Ventures Limited Partnership Accommodating intraocular lens
US5443506A (en) * 1992-11-18 1995-08-22 Garabet; Antoine L. Lens with variable optical properties
DE4403326C1 (en) * 1994-02-03 1995-06-22 Hans Reinhard Prof Dr Koch Intraocular lens arrangement for astigmatism correction

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11406490B2 (en) 2012-01-24 2022-08-09 Alcon Inc. Modular intraocular lens designs and methods
DE102014106374A1 (en) 2013-05-07 2014-11-13 Akkolens International B.V. Accommodating intraocular lens with sulcus fixation haptics
US9861469B2 (en) 2013-05-07 2018-01-09 Akkolens International B.V. Accommodating intraocular lens with haptics for sulcus fixation
CN110996847A (en) * 2017-06-27 2020-04-10 爱尔康公司 Injector, intraocular lens system, and related methods

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