CN101096017B - Modified type static inhalation toxicant exposure cabinet - Google Patents

Modified type static inhalation toxicant exposure cabinet Download PDF

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Publication number
CN101096017B
CN101096017B CN2007100277866A CN200710027786A CN101096017B CN 101096017 B CN101096017 B CN 101096017B CN 2007100277866 A CN2007100277866 A CN 2007100277866A CN 200710027786 A CN200710027786 A CN 200710027786A CN 101096017 B CN101096017 B CN 101096017B
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China
Prior art keywords
cabinet
type static
toxicant exposure
modified type
static inhalation
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Expired - Fee Related
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CN2007100277866A
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Chinese (zh)
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CN101096017A (en
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姚朗
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Southern Medical University
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Southern Medical University
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Abstract

The invention discloses a modified static inhaled toxicant exposure cabinet, comprising cabinet body (1), heater (10)and fan (9)set in the cabinet body (1), which is characterized in that the cabinet body (1)is a cylinder container; sample volatilizing box (6)is set under the cover plate (5); the volatilizing box (6)is a tetrahedron; evaporating dish (8)is set at the bottom and the heater (10)is set at the bottom of evaporating dish (8); the fan (9)is set at one end of volatilizing box (6)and oblique flow guide plate (11)is set at the other end; air outlet port (7)is set near the lower end of flow guide plate (11). The invention not only can improve concentration uniformity of test chemical in cabinet but also shorten testing time. It also saves electric energy and protects circumstance.

Description

A kind of modified type static inhalation toxicant exposure cabinet
Technical field:
The present invention relates to a kind of diagnostic instrument, be specifically related to toxicant exposure cabinet, type static inhalation toxicant exposure cabinet particularly, this cabinet are applicable to set up and suck the toxicology test that contamination animal model or research external source chemicals suck the toxicity of contamination.
Background technology:
Set up the mode that sucks the contamination animal model and mainly contain two kinds, a kind of is that quiet formula sucks contamination, and another kind is a dynamic inhalation contamination.It is that animal used as test is placed a closed container that a constant volume is arranged that quiet formula sucks contamination, add the gaseous state that a certain amount of volatile liquid state tried chemicals or certain volume and tried chemicals, in this closed container, form and contain the air ambient that desired concn tried chemicals and make animal contaminated.Dynamic inhalation contamination then is the toxicant exposure cabinet that places an air to flow animal used as test, and toxicant exposure cabinet is equipped with additional fresh air to be tried the dynamical system of chemicals mist and quantitatively replenish the air distribution system that is tried chemicals at any time with discharge.These two kinds suck contaminating modes its characteristics are respectively arranged: dynamic inhalation contamination relatively tallies with the actual situation, but the contamination device complexity costs an arm and a leg, and is very big to the consumption that is tried chemicals, and pollutes the operation room air ambient easily, less installation of common laboratory and use.It is cheap that quiet formula sucks the contamination equipment needed thereby, be easy to build, easy to operate, it is little to be tried the chemicals consumption, be particularly useful for education experiment and general acute, the inferior chronic and chronic suction viral infection test of toy, shortcoming is that contamination time is after causing degradation under the toxicant exposure cabinet partial pressure of oxygen for a long time.
The type static inhalation toxicant exposure cabinet structure that existing market provided is simple and crude, lack heater and lighting device, exist suck contamination time long, can not control the volatility liquid state and tried the liquid state of the evaporation rate of chemical substance, adding and tried problems such as chemicals easily drip at the bottom of the cabinet.State Intellectual Property Office discloses " a kind of type static inhalation toxicant exposure cabinet " on November 22nd, 2006, and (Granted publication number is: utility model patent CN 2838538Y), this patent scheme has a cuboid cabinet, the inboard, animal inlet top of cabinet also is provided with heater, and four jiaos are provided with air inlet, gas outlet and fan relatively.Though this patented technology has accelerated to be tried the evaporation rate of chemicals, the concentration uniformity of being tried chemicals in the cabinet is improved, but still there is following deficiency: the one, cabinet is a cuboid, there is the dead angle easily in the cabinet inner air flow, influence the concentration uniformity of being tried chemicals in the cabinet, the designer attempts to be remedied by the fan of two diagonal angle settings, but effect is still not very good, also wastes physical resources; The 2nd, the distance of placing the electro-heat equipment tried chemicals and fan is too far away, there are not organic connections between the two, the gas that produces when being tried the chemicals heated volatile can not be distributed in the whole cabinet timely and effectively, is unfavorable for being tried instant, the volatilization fast of chemical substance; The 3rd, need to add in advance to be tried to close the cabinet door again after the chemical substance, can cause a small amount of poisonous leaking of chemicals of being tried, both can influence accuracy of experimental results, can pollute laboratory environment and surrounding environment again, the harm health of operators; The 4th, the heating power of electro-heat equipment is fixed, and can not regulate heating power according to the volatilization complexity of being tried chemical substance, makes its volatilization fully within the predetermined time.
Summary of the invention:
In view of there is above-mentioned deficiency in prior art, technical problem underlying to be solved by this invention is further to improve the concentration uniformity of being tried chemical substance in the cabinet.
The technical scheme that the present invention solves the problems of the technologies described above is:
A kind of modified type static inhalation toxicant exposure cabinet, comprise cabinet and be located at cabinet interior heater and fan, it is characterized in that cabinet is a hydrostatic column, be provided with sample volatilization box below the cover plate on its mouthful, this volatilization box is a tetrahedron, and the bottom is provided with evaporating dish, the bottom of evaporating dish is provided with heater element, one end of box is provided with a desk fan, and the other end is provided with the deflector of an inclination, is provided with the gas outlet near the lower end of deflector.
Modified type static inhalation toxicant exposure cabinet of the present invention, wherein said heater element is a PTC heating sheet, its quantity is at least 3, generally be advisable with 3~6, the top of wherein said cover plate is provided with the multi-group power switch, so that regulate the heating power of PTC heating sheet according to the complexity of chemical substance volatilization.
Modified type static inhalation toxicant exposure cabinet of the present invention, the top of wherein said cover plate is provided with fan governor, so that regulate wind speed according to the complexity of gaseous volatilization.
Modified type static inhalation toxicant exposure cabinet of the present invention, the central authorities of wherein said cover plate are provided with a well, this hole is over against evaporating dish, can after putting animal subject into and building cover plate, add and be tried chemicals, avoid being influenced accuracy of experimental results because of adding in advance tries chemicals, and causing toxic gas to leak and pollution laboratory and surrounding environment, the harm operating personnel are healthy.
1/4 place (near tested animal place) also is provided with a gas sampling hole far from the bottom surface for modified type static inhalation toxicant exposure cabinet of the present invention, wherein said cabinet side, is used for experiment and extracts in the cabinet gas at any time and analyze.
Modified type static inhalation toxicant exposure cabinet of the present invention, wherein said cabinet are transparent pmma material, and the outside is provided with illuminating lamp thereafter, so that timely observation experiment situation.
Modified type static inhalation toxicant exposure cabinet of the present invention, wherein said bottom of cabinet bulk are provided with a blowoff valve, at the bottom of this valve has concurrently and is convenient to test the back combustion gas and cleans cabinet after these 2 kinds of purposes of waste discharge.
Modified type static inhalation toxicant exposure cabinet of the present invention, wherein said is cylinder, obviously reduce the cabinet inner air flow and had the dead angle easily, further again with evaporating dish, heater and fan are concentrated and are formed sample volatilization box, and the relative position of these parts has been carried out reasonable disposition, heater is directly heated tried chemicals, evaporation immediately, the chemicals gas that tried that is volatilized is in time blown out by the fan that is arranged on evaporating dish one end, air-flow turns to through the deflector of the evaporating dish other end, blow from top to bottom to bottom of cabinet bulk, and be dispersed into whole cabinet inner chamber rapidly, both effectively improved the concentration uniformity of being tried chemicals in the cabinet, shortened test period again, also saves energy.
Description of drawings
Fig. 1 and Fig. 2 are the structural representation of a kind of specific embodiment of the present invention, and wherein, Fig. 1 is a front view, and Fig. 2 is a upward view;
Fig. 3 and Fig. 4 are embodiment cover plate illustrated in figures 1 and 2 and the structural representation enlarged drawing that is located at the sample volatilization box under it, and wherein, Fig. 3 is a front view, and arrow is the air current flow direction among the figure, and Fig. 4 is a upward view.
The specific embodiment:
Referring to Fig. 1 and Fig. 2, the hydrostatic column of cabinet 1 for adopting the transparent organic glass pipe to make, upper end open, mouth is provided with cover plate 5, forms an airtight space in the cabinet 1.Be provided with sample volatilization box 6 (seeing Fig. 3 and Fig. 4) below the described cover plate 5.This volatilization box 6 is a tetrahedron, and the bottom is provided with evaporating dish 8, one ends and is provided with fan 9, and the deflector 11 of the other end for tilting is provided with gas outlet 7 near the lower end of deflector 11, and wherein 3 PTC heating sheets 10 are posted as heater in the bottom of evaporating dish 8.According to the quantity that the gasification point that is tried chemical substance suitably selects PTC heating sheet 10 to work, make and tried chemical substance volatilization fully within the predetermined time.In order to obtain wideer thermoregulation range or thinner temperature interval, the sheet 10 that PTC can be generated heat is increased to 6 even more.For the ease of operation, the power control switch 12 of PTC heating sheet 10 and fluorescent lamp 4 and the speed regulator 13 of fan 9 all be located at cover plate 5 above.The top of described cover plate 5 also is provided with thermometer hole 14 and well 15, and wherein well 15 is positioned at the central authorities of cover plate 5, and it is down over against evaporating dish 8.
Referring to Fig. 1 and Fig. 2, the outer rim of cabinet 1 oral area studs with the lucite edge of a wing 17, is provided with lucite reinforcement block 18 in this edge of a wing 17 and the formed armpit of cabinet 1 lateral wall, to improve the fastness that combines between cabinet 1 and the edge of a wing 17.
Referring to Fig. 1 and Fig. 2, the bottom of cabinet 1 is provided with 4 feets 3, and this feet 3 is propped up cabinet 1, is located at the space of cabinet 1 bottom so that blowoff valve 2 to be provided.
Referring to Fig. 1 and Fig. 2, the side of cabinet 1 is provided with gas sampling hole 16, and the outside, back is provided with illumination fluorescent lamp 4, and wherein gas sampling hole 16 is apart from 1/4 place, bottom surface of cabinet, promptly near the animal subject place.
Well 15 described in the present embodiment, thermometer hole 14 and thief hole 16 all can adopt the rubber stopper sealing.
The using method of the described type static inhalation toxicant exposure cabinet of present embodiment can follow these steps to carry out:
1, with animal used as test (normally mouse or rat) from cabinet 1 cabinet of putting into suitable for reading, observe normal condition rear enclosed well 15, thermometer hole 14 and gas sampling hole 16 before the experimental animal contamination in the cabinet;
2, cover cover plate 5 (between the edge of a wing 17 of cover plate 5 and cabinet 1, coating sealing substances such as vaseline earlier), the inside and outside air exchange of isolated cabinet;
3, connect the power supply of fluorescent lamp 4;
4, add an amount of volatility liquid state from well 15 and tried chemicals in stainless steel evaporating dish 8, gaseous state is tried chemicals and is also added through this well 15.Seal well 15 with rubber stopper earlier behind the application of sample, open the gauge tap of fan 9 and PTC heating sheet 10 again, room temperature during according to the volatility of being tried chemical substance and test is regulated the wind speed of fan 9 and the unlatching group number of control PTC heating sheet 10, make and tried chemicals and in the required time, volatilize and finish, disconnect the power supply of PTC heating sheet 10 thereafter;
5, observe and write down and tried the toxicity of chemicals experimental animal.
6, open well 15 and thermometer hole 14 earlier during off-test, open blowoff valve 2 again, connect blast pipe to aspiration pump for combustion gas and suitably handle in order to avoid contaminated environment.
7, open cover plate 5, take out the experimental animal of placing at the bottom of the cabinet, clean at the bottom of the cabinet, waste water and animal wastes etc. are discharged by sunk type blowoff valve 2.

Claims (8)

1. modified type static inhalation toxicant exposure cabinet, comprise cabinet (1) and be located at cabinet (1) interior heater (10) and fan (9), it is characterized in that cabinet (1) is a hydrostatic column, be provided with sample volatilization box (6) below its cover plate (5), this volatilization box (6) is a tetrahedron, the bottom is provided with evaporating dish (8), one end is provided with fan (9), the deflector (11) of the other end for tilting, lower end near deflector (11) is provided with gas outlet (7), and wherein the bottom of evaporating dish (8) is provided with heater (10).
2. a kind of modified type static inhalation toxicant exposure cabinet according to claim 1 is characterized in that described heater (10) is PTC heating sheet, and its quantity is at least 3.
3. a kind of modified type static inhalation toxicant exposure cabinet according to claim 2 is characterized in that described PTC heating sheet is 3~6.
4. a kind of modified type static inhalation toxicant exposure cabinet according to claim 1 is characterized in that the top of described cover plate (5) is provided with fan governor (13).
5. a kind of modified type static inhalation toxicant exposure cabinet according to claim 1 is characterized in that the central authorities of described cover plate (5) are provided with well (15), and this hole is over against evaporating dish (8).
6. a kind of modified type static inhalation toxicant exposure cabinet according to claim 1 is characterized in that 1/4 place is provided with a gas sampling hole (16) far from the bottom surface in described cabinet (1) side.
7. a kind of modified type static inhalation toxicant exposure cabinet according to claim 1 is characterized in that described cabinet (1) is transparent pmma material, and lateral surface is provided with illuminating lamp (4) thereafter.
8. according to one of them described a kind of modified type static inhalation toxicant exposure cabinet of claim 1~7, it is characterized in that described cabinet (1) bottom is provided with blowoff valve (2).
CN2007100277866A 2007-04-29 2007-04-29 Modified type static inhalation toxicant exposure cabinet Expired - Fee Related CN101096017B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2007100277866A CN101096017B (en) 2007-04-29 2007-04-29 Modified type static inhalation toxicant exposure cabinet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2007100277866A CN101096017B (en) 2007-04-29 2007-04-29 Modified type static inhalation toxicant exposure cabinet

Publications (2)

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CN101096017A CN101096017A (en) 2008-01-02
CN101096017B true CN101096017B (en) 2011-05-25

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102641156B (en) * 2012-05-03 2013-10-09 天津开发区合普工贸有限公司 Anti-explosion safe shielding device for gas contamination cabinet
CN109470594A (en) * 2018-10-29 2019-03-15 上海化工研究院有限公司 A kind of quantitative direct-evaporation-type toxicant exposure cabinet aerosol producer
CN110934646A (en) * 2019-12-20 2020-03-31 黔东南民族职业技术学院 Separately-stored livestock veterinarian toolbox with sterilization function
CN113081373A (en) * 2021-03-12 2021-07-09 中国石油化工股份有限公司 Inhalation contamination device for producing intermediate product/byproduct in ethylene glycol synthesis process and application

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Granted publication date: 20110525

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