CN101081859A - Rutin extraction method - Google Patents
Rutin extraction method Download PDFInfo
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- CN101081859A CN101081859A CN 200610014018 CN200610014018A CN101081859A CN 101081859 A CN101081859 A CN 101081859A CN 200610014018 CN200610014018 CN 200610014018 CN 200610014018 A CN200610014018 A CN 200610014018A CN 101081859 A CN101081859 A CN 101081859A
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- rutin
- impurity
- bitter buckwheat
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- extract
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Abstract
The process of extracting rutin includes the following steps: washing tartary buckwheat, crushing, stoving, extracting with methanol, filtering to eliminate fiber residue, distilling to recover methanol to obtain coarse extract; dissolving the coarse extract in isopropanol, depositing and filtering to eliminate impurity, recovering isopropanol to obtain extract; extracting the extract with trichloromethane, filtering to eliminate impurity to obtain coarse rutin product while recovering trichloromethane; dissolving coarse rutin product in mixed solvent of alcohol and ethyl acetate, filtering to obtain pure filtrate; adsorbing the filtrate, washing in column, concentrating the eluted liquid to recover alcohol, centrifugally filtering and stoving to obtain rutin product. The process has the advantages of facile materials, no environmental pollution and useability of the dregs as feed or fertilizer.
Description
Technical field
The present invention relates to a kind of rutin extraction method.
Background technology
At present, China extracts rutin from woody leguminous plants sophora bud bud, but this method raw material sources difficulty, complex process yields poorly.
Summary of the invention
The objective of the invention is to overcome above-mentioned defective, a kind of rutin extraction method is provided.
Technical scheme of the present invention is: a kind of rutin extraction method, and buckwheat powder is broken, oven dry, then by bitter buckwheat: the part by weight of solvent=1: 6-25 stirs extraction 4-24 hour with methyl alcohol under 65-80 ℃, filter and remove fibrous residue, the filtrate distillating recovering solvent gets the rutin crude extract; Above-mentioned rutin crude extract is pressed bitter buckwheat: the part by weight of solvent=1: 6-30 is removed impurity such as protein and part tannin, pigment with Virahol normal-temperature dissolution, precipitation, filtration, and the filtrate distillating recovering solvent gets the rutin extract; Above-mentioned rutin extract is pressed bitter buckwheat: the part by weight of solvent=1: 6-20 is used trichloromethane to heat down at 65-110 ℃ and was extracted 0.5-2 hour, filtration, and the filtrate distillating recovering solvent gets the rutin crude product; Above-mentioned rutin crude product is pressed bitter buckwheat: at 65-95 ℃ of following heated and stirred 0.5-2 hour, filtered while hot was removed filter residue, filtrate that must be purer to the part by weight of solvent=1: 5-20 with ethanol; Above-mentioned filtrate is adsorbed with adsorption column, wash post with methyl alcohol, elutriant reclaims solvent through distilling to concentrate, centrifuging, dry below 80 ℃ the elaboration rutin, add the gac of the heavy 0.3%-5% of filtrate in the filtrate before adsorbing, to remove impurity such as pigment.
The present invention has the following advantages: raw material is easy to get, the product yield height, and good product purity, production technique low toxicity, safety, the process time is short, and non-environmental-pollution, waste residue can be used as feed or fertilizer.
Embodiment
Embodiment: a kind of rutin extraction method, bitter buckwheat is cleaned, be ground into the length of 2-3mm, the moisture content of oven dry to 6%, then by bitter buckwheat: the part by weight of solvent=1: 6 stirs down at 65 ℃ with methyl alcohol and extracted in 24 hours, filter and remove fibrous residue, methyl alcohol is reclaimed in distillation, must contain tannin, protein, the rutin extract of impurity such as pigment, with the said extracted thing by bitter buckwheat: the part by weight Virahol normal-temperature dissolution of solvent=1: 6, precipitate 20 minutes after-filtration, removal protein and part tannin, impurity such as pigment, reclaim Virahol, must contain tannin, the rutin extract of impurity such as pigment; With the said extracted thing by bitter buckwheat: the part by weight of solvent=1: 6 extracted 2 hours down at 65 ℃ with trichloromethane, filter, remove tannin, impurity such as pigment, get the rutin crude product, reclaim trichloromethane, with above-mentioned rutin crude product by bitter buckwheat: the part by weight of solvent=1: 5 with the mixture of 55: 45 ethanol and vinyl acetic monomer 65 ℃ of stirrings 2 hours down, filtered while hot is removed filter residue, filtrate that must be purer, above-mentioned filtrate is adsorbed, adopt poly-phthalein amine adsorption column absorption rutin, wash post with 70% ethanol, concentrate eluant reclaims ethanol, centrifuging, dry below 80 ℃ the elaboration rutin.
Claims (1)
1, a kind of rutin extraction method, it is characterized in that: bitter buckwheat is cleaned, be ground into the length of 2-3mm, the moisture content of oven dry to 6%, then by bitter buckwheat: the part by weight of solvent=1: 6 stirs down at 65 ℃ with methyl alcohol and extracted in 24 hours, filter and remove fibrous residue, methyl alcohol is reclaimed in distillation, must contain tannin, protein, the rutin extract of impurity such as pigment, with the said extracted thing by bitter buckwheat: the part by weight Virahol normal-temperature dissolution of solvent=1: 6, precipitate 20 minutes after-filtration, removal protein and part tannin, impurity such as pigment, reclaim Virahol, must contain tannin, the rutin extract of impurity such as pigment; With the said extracted thing by bitter buckwheat: the part by weight of solvent=1: 6 extracted 2 hours down at 65 ℃ with trichloromethane, filter, remove tannin, impurity such as pigment, get the rutin crude product, reclaim trichloromethane, with above-mentioned rutin crude product by bitter buckwheat: the part by weight of solvent=1: 5 with the mixture of 55: 45 ethanol and vinyl acetic monomer 65 ℃ of stirrings 2 hours down, filtered while hot is removed filter residue, filtrate that must be purer, above-mentioned filtrate is adsorbed, adopt poly-phthalein amine adsorption column absorption rutin, wash post with 70% ethanol, concentrate eluant reclaims ethanol, centrifuging, dry below 80 ℃ the elaboration rutin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610014018 CN101081859A (en) | 2006-06-02 | 2006-06-02 | Rutin extraction method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610014018 CN101081859A (en) | 2006-06-02 | 2006-06-02 | Rutin extraction method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101081859A true CN101081859A (en) | 2007-12-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610014018 Pending CN101081859A (en) | 2006-06-02 | 2006-06-02 | Rutin extraction method |
Country Status (1)
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| CN (1) | CN101081859A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103030671A (en) * | 2012-11-26 | 2013-04-10 | 李玉山 | Preparation method of low color-value rutin |
| CN103833808A (en) * | 2013-12-03 | 2014-06-04 | 西安应化生物技术有限公司 | Method for extraction separation of rutin of tartary buckwheat |
| CN106071782A (en) * | 2016-06-16 | 2016-11-09 | 凉山孜莫拉魔芋产业发展有限公司 | A kind of processing method of Konjak fine dried noodle |
| CN107432304A (en) * | 2016-06-16 | 2017-12-05 | 西昌学院 | The processing method of buckwheat potato cake |
-
2006
- 2006-06-02 CN CN 200610014018 patent/CN101081859A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103030671A (en) * | 2012-11-26 | 2013-04-10 | 李玉山 | Preparation method of low color-value rutin |
| CN103833808A (en) * | 2013-12-03 | 2014-06-04 | 西安应化生物技术有限公司 | Method for extraction separation of rutin of tartary buckwheat |
| CN106071782A (en) * | 2016-06-16 | 2016-11-09 | 凉山孜莫拉魔芋产业发展有限公司 | A kind of processing method of Konjak fine dried noodle |
| CN107432304A (en) * | 2016-06-16 | 2017-12-05 | 西昌学院 | The processing method of buckwheat potato cake |
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Addressee: Li Defa Document name: Written notice of preliminary examination of application for patent for invention |
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