CN101053685A - Portable atomized medicine introducing device - Google Patents

Portable atomized medicine introducing device Download PDF

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Publication number
CN101053685A
CN101053685A CN 200610011639 CN200610011639A CN101053685A CN 101053685 A CN101053685 A CN 101053685A CN 200610011639 CN200610011639 CN 200610011639 CN 200610011639 A CN200610011639 A CN 200610011639A CN 101053685 A CN101053685 A CN 101053685A
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China
Prior art keywords
storage container
liquor storage
introducing device
physic liquor
atomized medicine
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Pending
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CN 200610011639
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Chinese (zh)
Inventor
陈清甫
李国增
周伟
范云清
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Individual
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Individual
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Priority to CN 200610011639 priority Critical patent/CN101053685A/en
Publication of CN101053685A publication Critical patent/CN101053685A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a portable atomization administration apparatus, including a case having an air hole, an active separator arranged in the case dividing the case into to two chambers, wherein one chamber is provided with a liquor storage container with one end connected with an electric control pump connecting the atomization nozzle, and the other end is provided with a pressure sensor connected with the input end of the control circuit, while the other chamber of the liquor storage container is equipped with a cell connected with a diode. The device has small volume, light weight, low cost, and easy to carry along and realize the precise control, which can work along the breath rhythm of the human. The users inhale the medicine atomization air actively and spiritedly, wherein the atomization air is warm to enhance the thermal effect and can not cause the cough. The liquor is easy to be inhaled into the human body, and improves the therapeutic. The invention has simple structure, simple operation, which is applicable for the household and the personal and easy to popularize.

Description

Portable atomized medicine introducing device
Technical field
The present invention relates to a kind of armarium, specifically, relate to a kind of portable atomized medicine introducing device of the medicine of packing into.
Background technology
In life, often use nebulizer to treat throat, trachea, bronchus or pulmonary disease.Nebulizer is to utilize hyperacoustic acoustic energy, and medicinal liquid is become trickle aerosol, with people's the air-breathing absorption that enters respiratory tract in order to blood capillary, the aerosol particles diameter of atomizing is 1-5 μ m, can reach the respiratory bronchioles position deeply during suction, and drug waste is few, effect is remarkable, few side effects.But in actual applications,, must add cold water again in tank and the atomization tank, cause the atomization gas temperature to reduce because of the piezoelectric ceramic piece in the nebulizer just quits work after being heated.The low temperature atomization gas does not have too much influence to the adult of general health, but to old, chronic, postoperative patient, behind a large amount of fast suction atomization gas such as child, because of differing greatly with body temperature, can make and pharyngeally feel intensive cold stimulation, thereby bring out apasm of coughing, interrupt using, and atomization gas does not have the physical action of heat, has reduced therapeutic effect.And the nebulizer that generally uses at present all is continuous atomised form, or with the irrelevant timing of people's breath rhythm atomised form intermittently, atomization gas is to be sent outside the machine by the air-blast device in the nebulizer, nebulizer one energized, just atomizing or self-timing intermittently atomize continuously, and aerator is continuously sent the atomization gas in the aerochamber outside the machine in the machine.Because this class nebulizer not only is equipped with aerator in complex circuit, the machine, volume is big, price is high, inconvenience is carried the medium limited occasion of can only being in and is used, and can not carry out work according to people's breath rhythm, the vaporific gas of sending in the slave continually, just therapist is had more visitors or business than one can attend to, cause cough easily, have influence on the acceptance and the therapeutic effect of therapist, and cause the waste of electric energy and about liquid.The general per minute of people's eupnea carries out about 12 times approximately, the time ratio of exhaling and inhaling generally is about 1: 1 to 1.2: 1, therefore when treatment, the maximum per minutes of nebulizer only need send mist half a minute just enough, so existing nebulizer is that electricity wasting expense and medicinal liquid are bigger to treating, and is very unpractical.
Summary of the invention
(1) technical problem that will solve
The objective of the invention is provides a kind of portable atomized medicine introducing device of the medicine of packing at above-mentioned the deficiencies in the prior art.
(2) technical scheme
For achieving the above object, the present invention adopts following technical scheme:
Portable atomized medicine introducing device of the present invention, comprise housing with pore, in housing, be provided with the active clapboard that housing is divided into two chambers, one of them indoor physic liquor storage container that is provided with, one end of this physic liquor storage container is connected with the automatically controlled pump that is connected with atomizing nozzle, the other end is provided with the stream pressure pick off that is connected with the input of control circuit, the indoor battery that is provided with of another of physic liquor storage container, and this battery is connected with a diode.
Described high temperature atomizing nozzle links to each other with the physic liquor storage container that medicinal liquid solution is housed through automatically controlled pump, atomizing nozzle inwardly is disposed with electrical heating elements from the mouth of pipe, high frequency nebulizer and control circuit, 3 outfans on the circuit board of installation control circuit, be connected with high frequency generator, atomizing nozzle and automatically controlled pump respectively, the high frequency nebulizer is connected with high frequency generator, and described stream pressure pick off is connected with the input of control circuit.
Described battery is disposable battery or chargeable battery, is installed on the insulating battery mounting, and its negative pole end is provided with spring.
Described housing profile is straight tube-like or slightly shaped form or the form of a stroke or a combination of strokes or cigarette holder shape.The opening of housing is equipped with ornament.
Described high frequency generator is the bikini electric capacity agitator that integrated circuit and field effect transistor are formed, and frequency is between 35KHz to 20MHz.
The material of described physic liquor storage container is a silicone rubber, and the feed flow coma of being made by natural fiber or synthetic fibers is arranged in the physic liquor storage container.
(3) beneficial effect
Portable atomized medicine introducing device of the present invention is compared with existing nebulizer following advantage and good effect:
1, this atomising device can be worked with people's breath rhythm automatically, be that the people is when air-breathing, the work of this atomising device, like this by user be initiatively, spiritedness preparatively inhalation put atomization gas, atomization gas is warm, strengthens thermotherapy and imitates, and what can not cause cough, medical liquid atomizing gas is inhaled into human body easily, improves and lifts therapeutic effect.When the people exhaled, this atomising device quit work, and had avoided medicinal liquid and waste of electric energy.
2, this atomising device volume is little, in light weight, cost is low, easy to carry, realizes accurately control easily.Noise is little, and particle size distribution is more concentrated, and the controlled amount of initial velocity can realize advantages such as dosed administration, thereby realize portable construction.
3, this atomising device is simple in structure, easy and simple to handle, is suitable for family and individual's use, is convenient to wide popularization and application.
4, this atomising device can be applicable to peptide class, the protein medicaments of antibiotic, antiviral agents, antihypertensive, angina pectoris treatment medicine and current concentrated research, even in the administration of some vaccines and other biological product.The medicine that must rely on for patient as the non-injection administration approach and the Common Pediatric Diseases of insulin, has social value and economic benefit more widely as the research of asthma and smoking cessation etc.
Only with regard to treatment asthma and smoking cessation, its market is huge.
Have 0.5% to suffer from asthma in the middle of the adult, and that the child suffers from asthma being comparatively common, approximately is adult ten times according to the document announcement child's who has asthma prevalence.The whole world has that the people suffers from asthma more than 100,000,000.
" Smoking is harmful to your health ", the words has been under the wheezy situation, and the whole world still has 1,000,000,000 people's smokings at present, and annual this numeral is also enlarging.
In fact, it is used more than that, at peptide class, the protein medicaments of antibiotic, antiviral agents, antihypertensive, angina pectoris treatment medicine and current concentrated research, insulin, some vaccines and other biological product, even in the administration of nanometer Chinese medicine, this device all has market greatly.
Description of drawings
Fig. 1 is the cutaway view of portable atomized medicine introducing device of the present invention;
Among the figure: 1. pebble or lucite medicated cap shape ornament; 2. light emitting diode; 3. housing; 4 batteries; 5. pore; 6. spring; 7. control circuit; 8. dividing plate; 9. high temperature atomizing nozzle; 10. automatically controlled pump; 11. physic liquor storage container; 12. stream pressure pick off; 13. suction nozzle; 14. battery mounting; 15. high frequency nebulizer; 16. electrical heating elements; 17. high frequency generator.
Below in conjunction with accompanying drawing, further describe the atomized medicine introducing device specific embodiment of the present invention, but be not used for limiting protection scope of the present invention.
The specific embodiment
Referring to Fig. 1.Portable atomized medicine introducing device of the present invention, comprise housing 3 with pore 5, in housing 3, be provided with the dividing plate 8 that housing is divided into two chambers, one of them indoor physic liquor storage container 11 that is provided with, one end of this physic liquor storage container is connected with the automatically controlled pump 10 that is connected with atomizing nozzle 9, the other end is provided with the stream pressure pick off 12 that is connected with the input of control circuit, the indoor battery 4 that is provided with of another of physic liquor storage container, and this battery is connected with a diode 2.
Described high temperature atomizing nozzle 9 links to each other with the physic liquor storage container 11 that medicinal liquid solution is housed through automatically controlled pump 10, and atomizing nozzle 9 inwardly is disposed with electrical heating elements 16 from the mouth of pipe, high frequency nebulizer 15 and control circuit 7.
3 outfans on the circuit board of installation control circuit are connected with high frequency generator 17, atomizing nozzle 9 and automatically controlled pump 10 respectively, and high frequency nebulizer 15 is connected with high frequency generator, and described stream pressure pick off 12 is connected with the input of control circuit.
Described battery 4 is installed on the insulating battery mounting 14, and its negative pole end is provided with spring 6, and this spring not only can be installed on the battery holder but also play cathode conductor battery is stable.
The end that high temperature atomizing nozzle 9 is installed is called suction end, and its termination is called suction nozzle 13.Its other end is called opening.
Heating element heater 16 and the automatically controlled pump 10 of control circuit in atomizing nozzle 9 provides starting current, make the medicinal liquid solution in sump assemblies pump into atomizing nozzle 9, liquid is under the high temperature dither ripple condition of atomizing nozzle 9, the atomizing ejection is condensed into smoke-like rapidly, and the duty of control circuit 7 is started by the stream pressure pick off 12 that is connected on the control circuit.By the battery 4 of control circuit to automatically controlled pump 10, high frequency generator 17,9 power supplies of high temperature atomizing nozzle, can be disposable, also can be chargeable battery.
Described diode can be yellow or other color,
Described housing profile is a straight tube-like, and also shaped form slightly can also be the common form of a stroke or a combination of strokes, cigarette holder shape or other design.The opening of housing is equipped with pebble or lucite medicated cap shape ornament 1.Pore 3 when the people is air-breathing on the housing enters air.
Described battery is a chargeable lithium cell, also Ni-MH battery.High frequency generator 17 is bikini electric capacity agitators that integrated circuit and field effect transistor are formed, frequency is at 35KHz to 20MHz, have Automatic Frequency trimming circuit and piezoelectric patches resonance in the circuit, the purpose that has the Automatic Frequency fine setting in its high frequency generator is to make piezoelectric patches be in resonance point all the time.
Physic liquor storage container is made by silicone rubber, also can not used by the submerged macromolecular compound of medicinal liquid, and the feed flow coma of being made by natural fiber or synthetic fibers is arranged in the physic liquor storage container.
Stream pressure pick off 12 is made by integrated thin-film thermistor array or silicon.Automatically controlled pump 10 is a kind of micropumps, is driven by linear electric motors, and the decelerator that drives large speed ratio through shaft coupling drives running with the low velocity high pulling torque, and little automatically controlled pump causes the contraction compressing by ferronickel memorial alloy or copper-based memory alloy silk at electric heating and constitutes on silicone rubber tube.High temperature atomizing nozzle 9 is the exotic materials with lower thermal conductivity, makes as aluminum silicate ceramic, is shaped as straight tube-like, its effective active length 3-20mm, and inner an internal diameter is arranged is the tubule of 0.05-2mm, this tubule is connected with electrical heating elements 16.High frequency nebulizer 15 and lumen shape design help liquid gasification and ejection; Electrical heating elements in the atomizing nozzle can be made with nichrome wire, platinum filament, tungsten platinum alloy silk, is shaped as linearity, single-screw shape.
The high frequency nebulizer comprises piezoelectric transducer and spray orifice face, and described piezoelectric transducer is to constitute by the elastic cavity film of circular piezoelectric potsherd and single crystal silicon material is bonding.The spray orifice face then is made of the micro-spraying hole array that is etched with some diameter unanimities on monocrystalline silicon piece, partly is the difference of oral cavity, nasal cavity, throat or pulmonary according to the mini spray administration, and the diameter of micro-spraying hole is generally between 3-20 μ m.Simultaneously, piezoelectric transducer and spray orifice face surround the liquid chambers of a sealing, and drug solution imports through inlet, thereby the medicinal liquid of realizing miniature spray is supplied with.At different application, the micro-spraying hole diameter can be adjusted between the 5-20 μ m, and the atomization particle diameter is 6-25 μ m.Provide the high speed Longitudinal Pressure Wave so that liquid sprays at a high speed through the micro-spraying hole place at the liquid emission direction.Ring piezoelectric sheet and another piezoelectric transducer of the bonding composition of atomizing diaphragm that has a micro-spraying hole provide the radial vibration ripple to the drop that is about to leave micro-spraying hole, make drop further broken.In the feed flow chamber of vibrating diaphragm and atomizing diaphragm composition, add a loose fiber and roll into a ball the energy and the liquid distribution that can improve each micro-spraying hole in the micro-spraying hole array, make it to be tending towards average.Vibrating diaphragm and atomizing diaphragm can be made with monocrystalline silicon piece or corrosion-resistant metal alloys.Change ring piezoelectric sheet and the driving voltage of circular piezoelectric sheet and the droplet distribution curve that frequency can obtain different-diameter.
The basic functional principle of device of the present invention is when suction nozzle 13 being placed on the mouth when air-breathing, stream pressure pick off 12 output signal of telecommunication start-up circuits, control circuit 7 is exported three driving voltages respectively, it is that the work of high frequency nebulizer atomizes that high-frequency oscillating circuits starts, another group direct current gradual change signal is supplied with yellow (or other colors), and light emitting diode 2 sends the gold-tinted of gradual change.The 3rd group starts automatically controlled pump 10, the medicinal liquid solution that is stored in the medical liquid container 11 is pumped in the high temperature atomizing nozzle 9, change into the drop that diameter is 1um-15um through little spraying, wherein 80% liquid-drop diameter is below 6um, after the air flow of air inlet 5 mixes, can arrive in bronchioles and the alveolar, each liquid supply rate is between 3-50 rises, medicinal liquid solution is gasificated into high-temperature steam and sprays to opening on the heating of jet pipe, the steam after the ejection expands in atmosphere and is condensed into the mist droplet of cigarette shape.
The effect of described high frequency nebulizer is: one, make the big drop that is in the unstable thermal current of high pressure fully contact gasification with heating element heater, two, to be in the jet pipe drop directly fragmentation atomize three, the bumping problem of solution liquid when being above the boiling point.Comprehensive atomizing effect can make the smog fogdrop diameter at 0.2um-3um.Easier the entering in the alveolar of Da Xiao droplet absorbs like this, and the diluent air stream that pneumatic sensor enters air inlet 3 when " breathing " action takes place is responsive, and its transducing signal input control circuit ends the power supply to automatically controlled pump and electric heating suggestion after delaying time.The time-delay of automatically controlled pump and heating is closed: after heating starts, start through 0.5 second automatically controlled pump 10 in time-delay back, automatically controlled pump control circuit close the back time-delay after 0.5 second electric heater close again, its objective is after quantitative transfusion the liquid noresidue that is gasified totally.Yellow light-emitting diode flash of light in each the breathing, flash signal provides a square-wave signal of 2 seconds by control circuit, makes flash of light be the variation of going out with bright.
Of the present invention with the little atomization of drug solns, per os sucks in the lung and absorbs, and is a kind of atomized medicine introducing device of hommization more.
More than be preferred forms of the present invention, according to content disclosed by the invention, some identical, replacement schemes that those of ordinary skill in the art can expect apparently all should fall into the scope of protection of the invention.

Claims (8)

1, portable atomized medicine introducing device, it is characterized in that comprising housing (3) with pore (5), in housing (3), be provided with the active clapboard (8) that housing is divided into two chambers, one of them indoor physic liquor storage container (11) that is provided with, one end of this physic liquor storage container is connected with the automatically controlled pump (10) that is connected with atomizing nozzle (9), the other end is provided with the pressure transducer (12) that is connected with the input of control circuit, the indoor battery (4) that is provided with of another of physic liquor storage container, this battery is connected with a diode (2).
2, atomized medicine introducing device according to claim 1, it is characterized in that described high temperature atomizing nozzle (9) links to each other with the physic liquor storage container that medicinal liquid solution is housed (11) through automatically controlled pump (10), atomizing nozzle (9) inwardly is disposed with electrical heating elements (16) from the mouth of pipe, high frequency nebulizer (15) and control circuit (7), 3 outfans on the circuit board of installation control circuit, respectively with high frequency generator 17, atomizing nozzle (9) is connected with automatically controlled pump (10), high frequency nebulizer (15) is connected with high frequency generator 17, and described stream pressure pick off (12) is connected with the input of control circuit.
3, atomized medicine introducing device according to claim 1 and 2 is characterized in that described battery (4) is disposable battery or chargeable battery, is installed on the insulating battery mounting (14), and its negative pole end is provided with spring (6).
4, atomized medicine introducing device according to claim 1 and 2 is characterized in that described housing profile is straight tube-like or slightly shaped form or the form of a stroke or a combination of strokes or cigarette holder shape. the opening of housing is equipped with ornament (1).
5, atomized medicine introducing device according to claim 4 is characterized in that described high frequency generator 17 is bikini electric capacity agitators that integrated circuit and field effect transistor are formed, and frequency is between 35KHz to 20MHz.
6, atomized medicine introducing device according to claim 3 is characterized in that the material of described physic liquor storage container (11) is a silicone rubber, and the feed flow coma of being made by natural fiber or synthetic fibers is arranged in the physic liquor storage container.
7, atomized medicine introducing device according to claim 4 is characterized in that the material of described physic liquor storage container (11) is a silicone rubber, and the feed flow coma of being made by natural fiber or synthetic fibers is arranged in the physic liquor storage container.
8, atomized medicine introducing device according to claim 5 is characterized in that the material of described physic liquor storage container (11) is a silicone rubber, and the feed flow coma of being made by natural fiber or synthetic fibers is arranged in the physic liquor storage container.
CN 200610011639 2006-04-10 2006-04-10 Portable atomized medicine introducing device Pending CN101053685A (en)

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Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008055423A1 (en) * 2006-11-10 2008-05-15 Li Han Aerosolizing inhalation device
WO2008058455A1 (en) * 2006-11-11 2008-05-22 Tafelberg International Limited Pulmonary medicament delivery device
CN103126765A (en) * 2013-03-25 2013-06-05 河南绿荫科贸有限公司 Pharyngitis therapeutic device
WO2015196379A1 (en) * 2014-06-25 2015-12-30 Outstanding Healthcare Company Limited A micro-humidifier
CN105194782A (en) * 2014-06-25 2015-12-30 卓效医疗有限公司 Micro humidifier
CN105413026A (en) * 2015-11-27 2016-03-23 吉林大学 Special atomizer facilitating aerosol inhalation of patient with cough
CN105496587A (en) * 2016-01-20 2016-04-20 深圳市赫拉铂氢时代科技有限公司 Micron/nano hydrogen water jet oral cavity cleaning instrument and cleaning method
CN105749385A (en) * 2016-02-01 2016-07-13 北京怡和嘉业医疗科技有限公司 Medicine spraying control method and medicine spraying control device for atomizer and atomizer
CN106390252A (en) * 2016-08-30 2017-02-15 苏州品诺维新医疗科技有限公司 Liquid medicine atomization apparatus and liquid medicine atomization method
CN106573123A (en) * 2014-06-30 2017-04-19 Syqe医药有限公司 Methods, devices and systems for pulmonary delivery of active agents
US20170360089A1 (en) 2010-12-22 2017-12-21 Syqe Medical Ltd. Method and system for drug delivery
CN108030663A (en) * 2017-12-07 2018-05-15 广东捷成科创电子股份有限公司 A kind of micro-sprayer that moisturizing improving eyesight is carried out using tea
CN109498920A (en) * 2018-07-17 2019-03-22 上海合微智能科技有限公司 Portable multi-function atomizer
CN109793967A (en) * 2019-01-31 2019-05-24 黄宏伟 A kind of anaesthetic atomizer
US11160937B2 (en) 2014-06-30 2021-11-02 Syqe Medical Ltd. Drug dose cartridge for an inhaler device
US11291781B2 (en) 2014-06-30 2022-04-05 Syqe Medical Ltd. Flow regulating inhaler device
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
US11311480B2 (en) 2014-06-30 2022-04-26 Syqe Medical Ltd. Method and device for vaporization and inhalation of isolated substances
CN114452494A (en) * 2022-02-23 2022-05-10 四川大学华西医院 Respiratory medicine atomization drug delivery device capable of adjusting drug delivery speed
US11806331B2 (en) 2016-01-06 2023-11-07 Syqe Medical Ltd. Low dose therapeutic treatment

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008055423A1 (en) * 2006-11-10 2008-05-15 Li Han Aerosolizing inhalation device
WO2008058455A1 (en) * 2006-11-11 2008-05-22 Tafelberg International Limited Pulmonary medicament delivery device
US20170360089A1 (en) 2010-12-22 2017-12-21 Syqe Medical Ltd. Method and system for drug delivery
US11071712B2 (en) 2010-12-22 2021-07-27 Syqe Medical Ltd. Method and system for drug delivery
US11766399B2 (en) 2010-12-22 2023-09-26 Syqe Medical Ltd. Method and system for drug delivery
CN103126765A (en) * 2013-03-25 2013-06-05 河南绿荫科贸有限公司 Pharyngitis therapeutic device
WO2015196379A1 (en) * 2014-06-25 2015-12-30 Outstanding Healthcare Company Limited A micro-humidifier
CN105194782A (en) * 2014-06-25 2015-12-30 卓效医疗有限公司 Micro humidifier
US11311480B2 (en) 2014-06-30 2022-04-26 Syqe Medical Ltd. Method and device for vaporization and inhalation of isolated substances
CN106573123A (en) * 2014-06-30 2017-04-19 Syqe医药有限公司 Methods, devices and systems for pulmonary delivery of active agents
US12016997B2 (en) 2014-06-30 2024-06-25 Syqe Medical Ltd. Flow regulating inhaler device
US11160937B2 (en) 2014-06-30 2021-11-02 Syqe Medical Ltd. Drug dose cartridge for an inhaler device
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
US11291781B2 (en) 2014-06-30 2022-04-05 Syqe Medical Ltd. Flow regulating inhaler device
CN105413026A (en) * 2015-11-27 2016-03-23 吉林大学 Special atomizer facilitating aerosol inhalation of patient with cough
US11806331B2 (en) 2016-01-06 2023-11-07 Syqe Medical Ltd. Low dose therapeutic treatment
CN105496587A (en) * 2016-01-20 2016-04-20 深圳市赫拉铂氢时代科技有限公司 Micron/nano hydrogen water jet oral cavity cleaning instrument and cleaning method
CN105749385A (en) * 2016-02-01 2016-07-13 北京怡和嘉业医疗科技有限公司 Medicine spraying control method and medicine spraying control device for atomizer and atomizer
CN106390252B (en) * 2016-08-30 2019-07-30 苏州涵轩信息科技有限公司 A kind of medicinal liquid atomizer
CN106390252A (en) * 2016-08-30 2017-02-15 苏州品诺维新医疗科技有限公司 Liquid medicine atomization apparatus and liquid medicine atomization method
CN108030663A (en) * 2017-12-07 2018-05-15 广东捷成科创电子股份有限公司 A kind of micro-sprayer that moisturizing improving eyesight is carried out using tea
CN109498920A (en) * 2018-07-17 2019-03-22 上海合微智能科技有限公司 Portable multi-function atomizer
CN109498920B (en) * 2018-07-17 2024-04-26 上海合微智能科技有限公司 Portable multifunctional atomizer
CN109793967A (en) * 2019-01-31 2019-05-24 黄宏伟 A kind of anaesthetic atomizer
CN114452494A (en) * 2022-02-23 2022-05-10 四川大学华西医院 Respiratory medicine atomization drug delivery device capable of adjusting drug delivery speed

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