CN101049387B - Composition of Chinese traditional medicine for treating rheumatic bone disease - Google Patents
Composition of Chinese traditional medicine for treating rheumatic bone disease Download PDFInfo
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- CN101049387B CN101049387B CN2007101078060A CN200710107806A CN101049387B CN 101049387 B CN101049387 B CN 101049387B CN 2007101078060 A CN2007101078060 A CN 2007101078060A CN 200710107806 A CN200710107806 A CN 200710107806A CN 101049387 B CN101049387 B CN 101049387B
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Abstract
A Chinese medicine in the form of powder for treating rheumatic and rheumatoid diseases, periomethritis, narrow canalis vertebralis, ischias, etc is prepared from 18 Chinese-medicinal materials including white mustard seed, safflower, myrrh, musk, etc through pulverizing, spraying the spirit solution of musk, and stirring.
Description
Technical field
The present invention relates to a kind of Chinese powder medicine, particularly relate to a kind of Chinese medicine composition of the treatment of collateral dredging reducing swelling and alleviating pain fast rheumatic osteopathia.
Technical background
Rheumatism is a kind of common clinical, frequently-occurring disease.Show that according to investigations about 400,000,000 people of rheumatisant are suffered from the whole world, are class illness the hugest in the medical domain.According to the health ministry investigation statistics, annual because of rheumatism, rheumatoid, osteopathia, directly or indirectly death toll reaches 1,500,000 people approximately, and annual rheumatisant's medication amount of money has all surpassed 200 hundred million! China has at least 200,000,000 people tormented by this pertinacious disease, and 80% is effectively treated, and controls repeatly and does not heal, and sb.'s illness took a turn for the worse, is forced to the edge of paralysis, at every moment urges residual human beings'health, makes patient's pain, makes the doctor have a headache.Therefore, treatment rheumatism, rheumatoid, osteopathia are very urgent things.Common rheumatism has rheumatism, rheumatoid arthritis, cold rheumatoid joint pain, gout, ankylosing spondylitis, osteoporosis, hyperosteogeny, proliferative arthritis, scapulohumeral periarthritis, lupus erythematosus, puerperal exposure to wind, intractable lumbago and skelalgia, sciatica, sjogren syndrome etc.Generally be the bonded method in Chinese and Western to rheumatismal treatment at present, and most of medicine only acts on the osteoarthrosis surface and carries out general easing pain and diminishing inflammation effect, can't enter the inner rheumatism virus of thoroughly removing of osteoarthrosis at all.For many years, western medical treatment rheumatism, rheumatoid mainly adopt anti-inflammatory analgesic class Western medicine, can only take stopgap measures and can not effect a permanent cure, and form drug dependence, lead to complications increase day by day, renal function injury is increasing, wrecking the people physical and mental health, shortening the human life-span.And traditional Chinese traditional treatment method also is difficult to make " rheumatism, rheumatoid " to obtain radical cure." pharmaceutical composition and the preparation method of treatment cerebral infarction sequela, rheumatic arthritis " application of 200610018453 application number was disclosed on national intellectual property patent gazette is on February 28th, 2006, it adopts compositions such as Rhizoma Corydalis Decumbentis, Rhizoma corydalis decumbentis total alkaloids, Moschus, Herba Siegesbeckiae, Caulis Spatholobi, Radix Clematidis, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Radix stephaniae tetrandrae, Rhizoma Atractylodis, Radix Achyranthis Bidentatae, Radix Angelicae Pubescentis, Olibanum (processed), Myrrha (processed), Radix Saposhnikoviae, Rhizoma Drynariae, Semen Strychni, Bombyx Batryticatus, Scorpio, though but relaxing muscles and tendons and activating QI and blood in the collateral, promoting the circulation of blood pain relieving, the course of treatment is long.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of instant effect, short treating period, few side effects, with the Chinese herbal medicine Chinese medicine composition that the master can treat rheumatic osteopathia fast.
The object of the present invention is achieved like this: a kind of Chinese medicine composition for the treatment of rheumatic osteopathia, form by following medicine according to percentage by weight calculating,
Semen Sinapis Albae 29%～35%, Rhizoma Arisaematis 6%～12%, Radix Aconiti 6%～12%, Radix Aconiti Kusnezoffii 6%～12%, Herba Asari 6%～12%, Radix Clematidis 6%～12%, Semen Strychni 2%～8%, ZHENMEIPIAN 2%～4%, Radix Dipsaci 1.5%～2.5%, Pyritum 1.5%～2.5%, Flos Carthami 1.5%～2.5%, Olibanum 1.5%～2.5%, Myrrha 1.5%～2.5%, Herba speranskiae tuberculatae 1.2%～2.7%, Herba Lycopodii 0.5%～1.5%, Sanguis Draxonis 0.5%～1.5%, Squama Manis 0.5%～1.5%, Moschus 0%～0.1%.
Pharmaceutical composition optimum weight percentage ratio of the present invention is:
Semen Sinapis Albae 32%, Rhizoma Arisaematis 9%, Radix Aconiti 9%, Radix Aconiti Kusnezoffii 9%, Herba Asari 9%, Radix Clematidis 9%, Semen Strychni 5%, ZHENMEIPIAN 3%, Radix Dipsaci 2%, Pyritum 2%, Flos Carthami 2%, Olibanum 2%, Myrrha 2%, Herba speranskiae tuberculatae 1.95%, Herba Lycopodii 1%, Sanguis Draxonis 1%, Squama Manis 1%, Moschus 0.05%.Wherein Herba Asari is a root of taking from it.
Above-mentioned Chinese crude drug (except that Moschus) is weighed according to percentage by weight, and 120 mesh sieves, standby altogether ground to the powder; Again with Moschus according to percentage by weight weigh, with 15 milliliters of Chinese liquor dissolve the back be sprayed onto in the above-mentioned mixed powder evenly in the medicamental pulverata ratio stir, sealed package.Packing is transferred the cream external application by 35 gram/bags.
During use, can be affixed on the affected part with medicated powder with hot water furnishing thick paste, generally applying the cream time is 60～120 minutes, each medication interval 5～9 days, and the general patient treatment phase can fully recover for 3～5 times.
The present invention fully uses Chinese medical theory, has used in ProductName of the present invention " the deep pain-relieving powder for treating of Moschus collateral dredging ":
With Semen Strychni, Rhizoma Arisaematis, Herba Asari, Radix Clematidis etc. is monarch drug, expelling wind and removing dampness cold expelling, promoting the flow of QI in the collateral by warming the meridian pain relieving; Flos Carthami, Radix Dipsaci, Semen Sinapis Albae, Pyritum etc. are ministerial drug, blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, bone strengthening removing obstruction in the collateral to relieve pain; Herba Lycopodii, Squama Manis, Pyritum, Sanguis Draxonis etc. are adjuvant drug, to strengthen the effect of expelling wind and removing dampness cold expelling, blood circulation promoting and blood stasis dispelling, warming the meridian eliminating stagnation, reducing swelling and alleviating pain; With Moschus, Borneolum Syntheticum is messenger drug, the collateral dredging that makes it to have one's ideas straightened out, saturating flesh bone, gets rid of evils and goes out, and pain is removed.
Compared with the prior art, the present invention is simple, the short treating period of preparation technology not only, and have expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, a promoting blood circulation to remove blood stasis, effects such as muscles and tendons relaxing to alleviate pain, remarkable to effects such as treatment rheumatism, rheumatoid, scapulohumeral periarthritis, numb limbs and tense tendons, general aching, spinal canal stenosis, sciatica, aseptic osteonecrosis, have no side effect.
The specific embodiment
Below in conjunction with embodiment the present invention is further detailed.
Case 1
Dong, the man, 78 years old, the Yueling City is Hu Jia people from village, local recklessly;
On October 19th, 2004 is when going to a doctor to this place, patient's right thigh radioactivity electric shock pain 5～6 days, intermittent claudication, 1～5 lumbar vertebra edge are hyperosteogeny, ossified, the waist sacrum gap turn narrow of anterior margin of vertebral body soft tissue, once examined into: lumbar spinal stenosis, lumbar degenerative change.Through external application the present invention " the deep pain-relieving powder for treating of Moschus collateral dredging " 5 times, every 5 days once, after 1 month, disease disappears, and follows up a case by regular visits to after 1 year, does not have recurrence.
Case 2
Song, male, 48 years old, people from Yueling City;
On May 6th, 2003, pain was 2～3 months under the right omoplate, does not have obvious pressure pain point, stomach discomfort during pain when going to a doctor to this place.Through external application the present invention " the deep pain-relieving powder for treating of Moschus collateral dredging " 1 bag/time, 90 minutes, sickly after 5 days accuse recovery from illness, follow up a case by regular visits to after 2 months, do not have recurrence.
Case 3
Zhang, woman, 64 years old, seven people from village Hu local Liu;
On October 13rd, 2006, left knee joint once was diagnosed as gonarthritis before 7 years, once took Western medicine, carried out block therapy when going to a doctor.Nearest 2 months inboard pain of right knee joint, swelling, not red not hot, after diagnosing: the cold arthritis of rheumatism.By external application the present invention " the deep pain-relieving powder for treating of Moschus collateral dredging " 1 bag 35 grams, applied ointment or plaster 90 minutes, according to every 5 days last medicines, pain complete obiteration after 3 times, recurrence so far.
From nineteen ninety, the present invention's " deep pain-relieving powder for treating of Moschus collateral dredging " carries out clinical trial to thousands of routine patients, and total effective rate is 96%.
One, rheumatoid arthritis: powdered repellent-antalgesic medicine
1, clinical data
Take randomized blocks, establish treatment group and matched group.18 examples are organized in treatment, reactive arthritis 8 examples wherein, rheumatoid arthritis 6 examples, osteoarthritis 4 examples; Matched group: reactive arthritis 12 examples in 18 examples, rheumatoid arthritis 3 examples, osteoarthritis 3 examples.
2 Therapeutic Method
Treatment group: with invention " the deep pain-relieving powder for treating of Moschus collateral dredging " treatment, external application; Matched group: local acupoint injection therapy ZHENGQINGFENGTONGNING, every day 1 time, each ml.
3 therapeutic outcomes
Efficacy determination: clinical cure, arthralgia disappears fully; Produce effects, arthralgia obviously disappear (disappearing 2/3); Take a turn for the better. arthralgia partly disappear (disappearing 1/3); Invalid: the arthralgia no change.Per 5 days 1 courses of treatment, promptly judge curative effect after finish 1 course of treatment.
Result: treatment group: pyretic arthralgia 14 examples, arthralgia aggravated by cold 4 examples are cured 14 examples, 3 examples that take a turn for the better, invalid 1 example cures 77%, total effective rate 94%;
Matched group: pyretic arthralgia 12 examples, arthralgia aggravated by cold 4 examples, 10 examples that take a turn for the better, invalid 6 examples, total effective rate 62.5%.
4 discuss:
The present invention adopts Chinese medicine to grind external (applying) into powder, just on the books as far back as Huatuo's epoch, ancient Chinese medicine doctor development exterior-applied prescription is innumerable, we are in treatment rheumatism process, once oral Chinese medicine cooperated acupoint injection therapy, arthralgia disappears not obvious, still developed " the deep pain-relieving powder for treating of Moschus collateral dredging " external application for curing arthritis, curative effect is very satisfied.Most of inflammatory arthritis all belong to traditional Chinese medical science pyretic arthralgia category, so reach antibacterial action with this medicine heat-clearing and toxic substances removing, play the reducing swelling and alleviating pain effect; And for non-inflammatory arthritis, as osteoarthritis, bursitis, we also more are aided with the medicine of blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian except that heat-clearing and toxic substances removing, make local normal circulation of qi and blood, general rule not bitterly, thereby reach the purpose of reducing swelling and alleviating pain.
Two, toxicity test:
Laboratory animal: get 24 of adult healthy SD rats, after adaptability fed for 1 week, be divided into 3 groups immediately, be i.e. blank group (A group), the deep pain-relieving powder for treating small dose group of Moschus collateral dredging (B group) and the deep pain-relieving powder for treating small dose group of Moschus collateral dredging (C group), 8 every group.
Medicine and reagent: the present invention's " deep pain-relieving powder for treating of Moschus collateral dredging "; Be mixed with every milliliter with distilled water and contain former medicine 0.5g (low dose), two kinds of dosage of 1.5g (heavy dose).
Method:
After SD rat adaptability fed for 1 week, begin to irritate stomach respectively, every day, the A group gave normal saline 2ml, and the B group gives the deep pain-relieving powder for treating 2ml of low dose of Moschus collateral dredging (0.5g/ml), and the C group gives the deep pain-relieving powder for treating 2ml of heavy dose of Moschus collateral dredging (1.5g/ml).1 week of continuous irrigation stomach, after not inferior administration, measure every right back sufficient sole of the foot volume of rat, observe its analgesic activity by writhing method, hot plate method, pressure tail method.30min after the not inferior administration, every right back sufficient plantar subcutaneous injection 1% agar 0.1ml of rat causes inflammation.1h, 2h, 3h, 4h, the right back sole of the foot volume of 5h difference continuous measurement rat after modeling calculate the swelling rate subsequently.
Swelling rate=(cause scorching metapedes sole of the foot volume-cause scorching front foot sole of the foot volume)/cause scorching front foot sole of the foot volume * 100%.After the agar modeling success, measure rat and cause scorching foot swelling rate and inflammatory tissue prostaglandin (PG E2) content.
The result:
The present invention's " deep pain-relieving powder for treating of Moschus collateral dredging " has good anti-inflammatory and analgesic effect, and can obviously reduce inflammatory tissue PGE2 content.
Conclusion:
The present invention's " deep pain-relieving powder for treating of Moschus collateral dredging " has stronger anti-inflammatory and analgesic effect.
Embodiment 1
Take by weighing Semen Sinapis Albae 160 grams, Rhizoma Arisaematis 45 grams, Radix Aconiti 45 grams, Radix Aconiti Kusnezoffii 45 grams, Herba Asari 45 grams, Radix Clematidis 45 grams, Semen Strychni 25 grams, ZHENMEIPIAN 15 grams, Radix Dipsaci 10 grams, Pyritum 10 grams, Flos Carthami 10 grams, Olibanum 10 grams, Myrrha 10 grams, Herba speranskiae tuberculatae 9.75 grams, Herba Lycopodii 5 grams, Sanguis Draxonis 5 grams, Squama Manis 5 grams according to percentage by weight, 120 mesh sieves, standby altogether ground to the powder; Again with Moschus according to 0.25 gram weigh, with 15 milliliters of Chinese liquor dissolve the back be sprayed onto in the above-mentioned mixed powder evenly in the medicamental pulverata ratio stir, sealed package, packing is by 35 gram/bags, the external application of accent cream.During use, can be affixed on the affected part with medicated powder with hot water furnishing thick paste, generally applying the cream time is 90 minutes, each medication interval 5～9 days, and the general patient treatment phase can fully recover for 3～5 times.
Embodiment 2
Take by weighing Semen Sinapis Albae 175 grams, Rhizoma Arisaematis 30 grams, Radix Aconiti 30 grams, Radix Aconiti Kusnezoffii 30 grams, Herba Asari 30 grams, Radix Clematidis 30 grams, Semen Strychni 10 grams, ZHENMEIPIAN 10 grams, Radix Dipsaci 7.5 grams, Pyritum 7.5 grams, Flos Carthami 7.5 grams, Olibanum 7.5 grams, Myrrha 7.5 grams, Herba speranskiae tuberculatae 1.2 grams, Herba Lycopodii 2.5 grams, Sanguis Draxonis 2.5 grams, Squama Manis 2.5 grams according to percentage by weight, 120 mesh sieves, standby altogether ground to the powder; Again with Moschus according to 0.01 gram weigh, with 15 milliliters of Chinese liquor dissolve the back be sprayed onto in the above-mentioned mixed powder evenly in the medicamental pulverata ratio stir, sealed package, packing is by 35 gram/bags, the external application of accent cream.During use, can be affixed on the affected part with medicated powder with hot water furnishing thick paste, generally applying the cream time is 60 minutes, each medication interval 5～9 days, and the general patient treatment phase can fully recover for 3～5 times.
Embodiment 3
Take by weighing Semen Sinapis Albae 145 grams, Rhizoma Arisaematis 60 grams, Radix Aconiti 60 grams, Radix Aconiti Kusnezoffii 60 grams, Herba Asari 60 grams, Radix Clematidis 60 grams, Semen Strychni 40 grams, ZHENMEIPIAN 20 grams, Radix Dipsaci 12.5 grams, Pyritum 12.5 grams, Flos Carthami 12.5 grams, Olibanum 12.5 grams, Myrrha 12.5 grams, Herba speranskiae tuberculatae 13.5 grams, Herba Lycopodii 7.5 grams, Sanguis Draxonis 7.5 grams, Squama Manis 7.5 grams according to percentage by weight, 120 mesh sieves, standby altogether ground to the powder; Again with Moschus according to 0.5 gram weigh, with 15 milliliters of Chinese liquor dissolve the back be sprayed onto in the above-mentioned mixed powder evenly in the medicamental pulverata ratio stir, sealed package, packing is by 35 gram/bags, the external application of accent cream.During use, can be affixed on the affected part with medicated powder with hot water furnishing thick paste, generally applying the cream time is 120 minutes, each medication interval 5～9 days, and the general patient treatment phase can fully recover for 3～5 times.
Claims (2)
1. Chinese medicine composition for the treatment of rheumatic osteopathia is characterized in that calculating according to percentage by weight and is made up of following medicine:
Semen Sinapis Albae 29%～35%, Rhizoma Arisaematis 6%～12%, Radix Aconiti 6%～12%, Radix Aconiti Kusnezoffii 6%～12%, Herba Asari 6%～12%, Radix Clematidis 6%～12%, Semen Strychni 2%～8%, Borneolum Syntheticum 2%～4%, Radix Dipsaci 1.5%～2.5%, Pyritum 1.5%～2.5%, Flos Carthami 1.5%～2.5%, Olibanum 1.5%～2.5%, Myrrha 1.5%～2.5%, Herba speranskiae tuberculatae 1.2%～2.7%, Herba Lycopodii 0.5%～1.5%, Sanguis Draxonis 0.5%～1.5%, Squama Manis 0.5%～1.5%, Moschus 0%～0.1%.
2. a kind of Chinese medicine composition for the treatment of rheumatic osteopathia according to claim 1 is characterized in that being made up of following medicine according to percentage by weight calculating:
Semen Sinapis Albae 32%, Rhizoma Arisaematis 9%, Radix Aconiti 9%, Radix Aconiti Kusnezoffii 9%, Herba Asari 9%, Radix Clematidis 9%, Semen Strychni 5%, ZHENMEIPIAN 3%, Radix Dipsaci 2%, Pyritum 2%, Flos Carthami 2%, Olibanum 2%, Myrrha 2%, Herba speranskiae tuberculatae 1.95%, Herba Lycopodii 1%, Sanguis Draxonis 1%, Squama Manis 1%, Moschus 0.05%, wherein Herba Asari is a root of taking from it.
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102552593B (en) * | 2012-01-19 | 2013-07-17 | 广州军区广州总医院 | Chinese medicinal composition for treating wind-cold-dampness arthralgia and using method thereof |
| CN102600257A (en) * | 2012-03-27 | 2012-07-25 | 李承平 | Medicinal composition for relaxing muscle, activating blood and relieving pain |
| CN103393872A (en) * | 2013-08-05 | 2013-11-20 | 王振卿 | Antirheumatic plaster and preparation method thereof |
| CN104208335A (en) * | 2014-09-10 | 2014-12-17 | 史子平 | Traditional Chinese medicine wet therapeutic bag for treating neck-shoulder and lumbocrural pains |
| CN104435496A (en) * | 2014-11-06 | 2015-03-25 | 张学举 | External traditional Chinese medicinal ointment for treating rheumatism and preparation method of traditional Chinese medicinal ointment |
| CN105055647A (en) * | 2015-09-17 | 2015-11-18 | 彭建国 | Traditional Chinese medicine composition for curing rheumatoid, stiffness and erythema and preparation method thereof |
| CN105168866A (en) * | 2015-10-26 | 2015-12-23 | 徐志英 | External traditional Chinese medicine for treating scapulohumeral periarthritis |
| CN105311514A (en) * | 2015-11-29 | 2016-02-10 | 蒋成友 | External-use Miao medicine liniment for treating bone diseases |
| CN106267080A (en) * | 2016-08-31 | 2017-01-04 | 唐秀宗 | For Chinese herbal medicine sticking acupuncture point and preparation method thereof, using method |
| CN108066736A (en) * | 2018-01-17 | 2018-05-25 | 肖春玲 | A kind of production method for the drug for treating rheumatism bone disease |
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2007
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Non-Patent Citations (2)
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| 权觉武.中药内外合治治疗中药内外合治治疗类风湿性关节炎的研究进展.中国民间疗法15 2.2007,15(2),62-63. |
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