CN101044857A - Application of compounding preparation in medicine for treating human Aids hepatitis and skin diseases - Google Patents
Application of compounding preparation in medicine for treating human Aids hepatitis and skin diseases Download PDFInfo
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Abstract
A composite medicine for treating human AIDS, hepatitis and dermatopathy is prepared from 36 Chinese-medicinal materials including yam, scutellaria root, rehmannia root, cordyceps, etc through pulverizing, sieving, extracting, concentrating, sterilizing, and shaping to become oral liquid, cream, pill, or capsule.
Description
The application of 1 compound preparation in treatment people AIDS-like disease hepatitis and skin diseases medicine, be a kind ofly to be used for the acquired immunodeficiency syndrome that viral disease such as antiviral, treatment acquired immune deficiency syndrome (AIDS), hepatitis, skin disease and acquired immune deficiency syndrome (AIDS) occur late period and the ancillary drug that designs is characterized in that it is the medicament of being made by following materials of weight proportions medicine: (unit: gram)
Chinese yam 1-36 root of large-flowered skullcap 1-30 wrinkled giant hyssop 1-30 gypsum 1-60
Rde bean 1-60 dried rhizome of rehmannia 1-36 dandelion 1-90 golden cypress 1-30
Chinese caterpillar fungus 1-90 root of herbaceous peony 1-30 calamus 1-36 radix bupleuri 1-30
Corydalis tuber 1-30 courage grass 1-30 bark of official magnolia 1-30 cape jasmine 1-30
Honeysuckle 1-45 rhizoma alismatis 1-30 Radix Glycyrrhizae 1-09 plantain seed 1-30
Rhizoma atractylodis 1-30 oriental wormwood 1-30 Asian puccoon 1-30 desmodium 1-60
The stiff silkworm 1-30 of bark of ash 1-30 oldenlandia diffusa 1-36 glossy ganoderma 1---90
Capsule of weeping forsythia 1-30 cassia twig 1-18 ginger 1-18 date 1---90
Selfheal 1-30 Chinese violet 1-60 sweet wormwood 1-30 chrysanthemum 1-30
2, compound preparation according to claim 1 is characterized in that at the medicine of treatment acquired immune deficiency syndrome (AIDS), hepatitis, skin disorder said medicament is the said formulation of any pharmacy.
3, medicine according to claim 2 is characterized in that described pharmaceutically dosage form is: capsule, nutrient solution, pulvis, paste, pill.
4, according to right 3 described process for preparing medicine, it is characterized in that adopting following technical process:
(1) refine:
Raw material is selected in a, discriminating.
B, the traditional Chinese medicine raw material is cut into slices.
C, with Chinese medicine crushing screening respectively.
D, will pulverize medicinal raw material, with 4～10 times, 1 ℃～100 ℃ floodings, each 1～5 hour, the lixiviate secondary merge concentrate, dry, pulverize.
E, will cut into slices glossy ganoderma and part traditional Chinese medicine, 65% ethanol that is used for 4～10 times of medicine weight soaked 7～15 days, after filtering with alcohol leaching thing water extract, according to science ratio combination formula low temperature treatment.
(2) preparation:
A, medicinal extract is added appropriate amount of starch and dextrin and alcohol leaching water extract, slip oil and the abundant mixed pelletization drying of ethanol, the encapsulated antimicrobin storehouse that checks in to steam.
B, medicinal extract concentrate dilution is added an amount of sweetener make nutrient solution, filter at low temperature (4 ℃～-2 ℃), sterilization, bottling quality inspection warehouse-in.
C, medicinal extract is added an amount of dextrin, starch, atomized drying is made electuary, pack quality inspection warehouse-in.
5, administrated method: by its short treating period of principle Orally taken and externally of returning the science of channels and collaterals (3 days is a course of treatment), instant effect (3 days take effect), be one-period 4 courses of treatment.
Method is as follows: took with 9 o'clock morning by late 9 o'clock (1).(2) take by 3 o'clock mornings and afternoon 3 o'clock.
Background: there are AIDS patient 5,000 ten thousand people in the whole world at present, is ascendant trend year by year; Hepatitis: hepatitis carrier 1.2 hundred million people have the part patient to transfer liver cancer to, so China also are the liver cancer districts occurred frequently; Do not have specific drug treatment acquired immune deficiency syndrome (AIDS), hepatitis B, hepatitis A (HAV), third liver (HCV), its oncoming force act of violence of viral hepatitis type E (HEV) at present, contagiosity is strong, and is serious to the damage of liver; Present treatment is to vaccinate; The present invention mainly provides a kind of instant effect, has no side effect, and can effectively treat acquired immune deficiency syndrome (AIDS), hepatitis B, the medicine of the complication of hepatitis A, hepatitis C, Hepatitis E and acquired immune deficiency syndrome (AIDS) appearance in late period.
AIDS virus: promptly human immunodeficiency virus (human immunodeficiency virus, HIV).(acquired immunodeficiency syndrome AIDS) is the No.1 killer of human diseases to the acquired immune deficiency syndrome (AIDS) that this virus causes.China found the first routine acquired immune deficiency syndrome (AIDS) (AIDS) 30 years so far from 1985.People develop into what is said or talked about AIDS till now and become with regard to look from ignorant to the attention.HIV paces up and down with you just as the demon, and you get vigilant constantly.Will involve pernicious consequences to you if you are careless slightly or unclean.So that become a member in the HIV infection.From HIV to AIDS, also have very long " ignorant " phase, make you have no to take precautions against,, arrived relevant disease (ARC) phase of AIDS in case find.This is just indicating and is entering the AIDS phase; Just indicating that also life closes to an end.Acquired immune deficiency syndrome (AIDS) is called as incurable disease, is because in a single day it develop into AIDS, almost yields to no remedy.The HIV aberration rate is exceedingly fast, and is just replaced by drug resistance strain fully in the body when a kind of medicine is used 14～28d
[1]This antibody just begins during from medication to produce.Another reason people can't obtain complete virion, and are difficult in treatment.
HIV belongs to Retroviridae (Retroviridae), lentivirus (Lentivirus), spirit palm class Slow virus group (Primatitentivirus group), para-immunity defective subgenus is slapped in spirit, is that the revertase (reverse transcriptase) of template synthetic DNA is gained the name with RNA.HIV is a RNA viruses, only infects spirit palm order animal.Found that human immunodeficiency virus has two kinds: HIV-1, HIV-2.HIV-2 is confined to western Africa, and virulence a little less than, the course of disease is long, mild symptoms.HIV-1 can cause the popular of global acquired immune deficiency syndrome (AIDS).The research of HIV at present, the laboratory, clinical all be based on HIV-1.Another member of this subgenus be gorilla, monkey (Simian immunodeficiencyvirus, SIV) similar to human HIV.In clinical trial, to set up model with it and carry out various experiments, the approach of its infection is the body fluid exchange.After HIV infects human body, mainly be to invade CD
4 +T lymphocyte and macrophage, receptors bind such as the CD4 of virion memebrane protein gp120 and cell surface and CCR5, and cause the change of a series of outer virionic membrane albumen space structures, finally cause outer virionic membrane and cell membrane to produce and merge; Virus core enters cell and slough protein shell under the work of enzyme is same.RT is the synthesizing single-stranded DNA of template with the viral RNA, thereupon through the archaeal dna polymerase synthetic double chain cDNA of cell; CDNA is through being incorporated into after the cyclisation on the cell chromosome, and viral nucleic acid passes daughter cell with cell division, and is very stable, can hide for a long time (Jin Qi edits " medical science viruses molecule " Science Press).Be transcribed into RNA in the fullness of time,, be assembled into the HIV core granule through a series of conversions, blastogenesis from the cell membrane, obtaining coating becomes ripe virus, infects new cell.
At present, not only infect lymphocyte and macrophage by discovering HIV, also infect the B cell, astrocyte in the enterocyte, brain and prominent less neurotic spongiocyte, and capillary endothelial cell cause the dirty damage of many devices.According to each one physique difference, the difference that the progress of HIV is free, the weakling will develop into AIDS in 6 months, and the body person of building just the AIDS symptom can occur in 8～10 years.That have even performance just arranged later in 15～20 years.In case the AIDS acquired immunodeficiency syndrome occurs, the neither one survivor.
The pathological change emphasis of AIDS 1 phase occurred in the thin system of lymph: the normal enlargement of lymph node.2 phases: enlarged lymph node retraction.3 phases: lymph dwindles, only remaining minority lymph follicle or full the disappearance.Lymphocyte is exhausted (burn-out).Lymph node generation fibrillatable.At thymus gland: thymus gland dwindles, and the cortilymph cell reduces even disappears, the medullary substance atrophy, and cortex is unclear with the medullary substance boundary, visible thick liquid cell, mast cell and multinucleate giant cell infiltration.At spleen: have the half patient that in various degree splenomegaly is arranged, at marrow: bone marrow smear changes not conform to the peripheral blood cells counting and the ineffective hematopoiesis phenomenon occurs, reticular fibre occurs and deposits and symptom such as increase.Enter axoneure at nervous system lesion: HIV by blood-brain barrier and cause multiple HIV meningitis, subacute encephalitis (AIDS chronic brain syndrome) nervous lesion, encephalatrophy, Deiter's cells hyperplasia at this moment occur or forms tubercle and demyelinate pathology; Cavity myelopathy: the marrow sheath occurs and attenuate and diseases such as vacuolar degeneration occur.
There is 15% patient to be associated with peripheral nerve injury.The supervention pathology, immunity is destroyed, many opportunistic illnesss have appearred, as, pneumocystis carinii pneumonia, toxoplasmosis, cryptococcosis, candidiasis, the infection of bird type Mycobacterium intracellulare, herpes simplex infections, cytomegalovirus infection, mycobacterium tuberculosis infection, Kaposis sarcoma etc. all are to control with the disease opinion in treatment.Some endemic mycosises are arranged, certain Characteristics of Geographical Distribution is arranged: Darling disease belongs to diphasic fungi, is present in to be subjected in the birds droppings contaminated soil: clinical manifestation is high heat, maculopapule or gangrenosum acne blood rash, hepatomegaly, splenomegaly, lymphnoditis, kitchen range etc. is soaked in anaemia and lung.Incomplete granuloma and lymphatic tissue cell aggregation appear in the posadasis spheriforme disease, with other opportunistic infections and deposit.Behind the patient's of AIDS the HSV infection morbidity, oral cavity, lip week appear, position bleb and damages such as genital tract and nasal cavity, and the retinitis or downright bad equivalent damage, serious difficult recovery of its damage.
Malignant tumour (KS) is modal malignant lymphoma and lymphadenopathy, as, the Huo Qijin malignant lymphoma; Also has other malignant tumour, T chronic myeloid leukemia, squama cancer, gland cancer, malignant mela noma, basal cell tumor, the carcinoma of the rectum, oral squamous cell carcinomas etc.Vascular lesion and connective tissue pathology all are the damages that virus immerses a series of human body that human body causes, the invasion of metabolic disorder and pathogeny microorganism causes.This product can obviously improve symptom, the activity of enhance immunity antibody; Remove virus, pathogenic microorganismss such as inhibition virus are to Normocellular injury, and repair cell is assisted the reparation of human body to impaired tissue.
Do not find protective immunity by African prostitute being infected example
[1], strengthen T lymphocyte reaction (CTL) activity of self cd4 cell mediation; By discovering that scope that CTL replys and intensity and CD4+T cell are proportionate, and are negative correlation with virus load; Phase when CTL has killed and wounded three: (1) contact: CTL contacts with target cell by adhesion molecule, and this process is several minutes.(2) by CTL particle born of the same parents release particles enzyme, perforin.
(3) cracking performance: occur a large amount of apertures on the target cell membrane, make moisture enter target cell and cause inside and outside differential pressure to increase spalling death.At present, China only is in elementary clinical stage aspect acquired immune deficiency syndrome (AIDS) research.Compare with HIV molecular biology research level, we are preliminary (Jin Qi edits " medical science viruses molecule ") to immunologic mechanism, the especially understanding of protective immunity mechanism that HIV infects.HIV enters the host and hides for a long time, and a small amount of virus protein structure representation is arranged again, causes " no antigen " genetic mutation and causes " neoantigen ", escapes immunity of organism supervision etc., all is the obstacle of research, has limited the development of vaccine.Therefore, need more research and analyse with a large amount of clinical.
Aspect the research of new drug, each state has all taked a lot of methods, develops many medicines.As the HAART of the U.S., the use by medical institutions such as BeiJing, China ditan hospitals has obtained good effect; But its side effect is big, and serious vomiting is arranged after the patient takes, and expensive expense makes many patients be difficult to bear.The Japan scholar sticks with paste soup with little bavin and makes electuary treatment acquired immune deficiency syndrome (AIDS), and the active of HIV-RT that can suppress 70% patient also can suppress PGE
2Generation with peroxide.Because virus is to be the host with the cell, consistent with the life cycle of cell, the corresponding pair cell of the medicine of some kill virus also kills and wounds.Therefore influenced the development of virus killing drug.In addition, there are some forbidden zones in human body, as blood-brain barrier, have only virus to come in and go out, and immunocyte can't enter (Bai Xuefan, Zhang Shulin." Clinics and Practices of acquired immune deficiency syndrome (AIDS) ").This provides sanctuary to virus, and treatment is got into a difficult position.In case the human body defense function goes down, virus will be walked crosswise once more.The development of therefore treating the medicine of acquired immune deficiency syndrome (AIDS) must be a prerequisite not injure normal cell.
The application of compound preparation in treatment people AIDS-like disease hepatitis and skin diseases medicine is to utilize traditional Chinese medicine in conjunction with modern biotechnology, for acquired immune deficiency syndrome (AIDS), hepatitis, treating for skin disease, adopt the strengthening the body resistance to consolidate the constitution of the traditional Chinese medical science, clearing heat and detoxicating, promoting blood circulation and removing blood stasis, strengthening vital QI to eliminate pathogenic factors, clearing liver cholagogic, strengthening the spleen and stomach to consider, from these row, concussion, resistance dawn, kill, repair five aspects and set about comprehensively.
These row: be the orderly metabolism of all immune systems, baicalin in the compound preparation and baicalein etc. can suppress the function of viral reverse transcription, and clearing heat and detoxicating effect is arranged.Can resist the activity of the reverse transcriptase HIV-RT of virus generation, make HIV can not transcribe maturation, assemble new individuality, and lose infection ability.
Concussion: the glycyrrhizin in the compound preparation, licoisoflavanone, disulfoxide etc., can suppress duplicating of HIV, suppress the expression of virus and antigen, make the virus that enters in the cell can't carry out self-replacation (the unlatching closure by cell is finished).
The resistance dawn: to the body of infective virus, selfheal element in the compound preparation and sulfated sugar etc. can be blocked HIV and combine with target cell.Salaspermic acid in compound preparation HIV active to HIV-RT and that infect in the H9 cell has inhibitory action.No. 1 Type B of infant genius in the compound preparation can be resisted virus and immunocyte be infected the defence capability of booster immunization cell.Make acceptors such as CD4-, CCR5 by combination competitively, thereby suppress the expression of HIV albumen.Big molecular saccharides PROTEIN C arrisyn can stop HIV to invade the T cell, increases CD4
+Cell and macrophage (CD
8 +The T lymphocyte) amount; CTL can secrete C-C chemotactic factor (CF), (giant cell inflammatory protein) MIP-la, MIP-l β etc., can combine inhibition HIV with chemokine receptor CCR 5 and enter cell.The antiviral cell of human body a new generation is produced.
Kill: the MAR-20 in the application composition of compound preparation in treatment people AIDS-like disease hepatitis and skin diseases medicine, α-Charantin, β-Charantins etc. can make that HIV's is ribosomal deactivated, GLQ-223, MAP-20 etc. are to the selective killing action of the macrophage of carrying HIV (Bai Xuefan, Zhang Shulin." Clinics and Practices of acquired immune deficiency syndrome (AIDS) "); After the CTL activation, FasL expresses, the death of Fas molecule inner segment, and activation cysteine proteinase 8 (caspase) causes the caspase cascade reaction, activates the DNA restriction endonuclease, makes the nucleosome fracture, causes cell structure to be damaged and death.CTL is by two kinds of mechanism (1) release particles enzyme, and the aperture that makes up by perforin enters cell, activates caspase10 and causes cascade reaction, causes Apoptosis, and kills the cell that is infected by HIV.(2) by activating the endogenous dna restriction endonuclease, the supply of blocking-up ATP energy; Quicken the programmed cell death of infected HIV.Make the immunocyte increment.
Repair:, cause the damage of many internal organs because HIV immune deficiency occurs to immune cell destruction; Biomembrane and compound preparation active ingredient in the present compound preparation of body dummy are repaired it, rebuild immune system.
For the virus that enters barrier zones, the micromolecule polypeptide in the compound preparation can directly enter, and penetrable barrier zones arrives focus, and virus is removed in effectively treatment.
The treatment of hepatitis: hepatitis viruse belongs to has a liking for liver venereal disease poison, its common feature: be to enter body, at first enter liver, duplicate in liver, and then be released into blood and bile; Destroy the function of liver, the infringement liver.Its treatment is a liver protecting, removes virus, repairs damaged tissues.
Hepatitis A (hepatitis A virus, HAV): its virion has stronger tolerance that organic solvent is had suitable resistance to the variation of factors such as temperature and PH; 81 ℃, 10 minutes, still have half virus survival; Stable when PH=3,20% ether can not deactivation.HAV is that the water source by food and pollution enters human body, enters liver cell by the surface of hepatocytes acceptor again.The phenomenon that causes liver cell to destroy mainly is cellular swelling, sex change and necrosis.HAV infects the later stage, and immune system is removed virus in body fully, also follows hepatocellular destruction and regeneration simultaneously.The medicine of the application of compound preparation in treatment human virus's property disease is embodied in the protection of its active ingredient to liver to the treatment of hepatitis A; strengthen natural killer cell (natural killer cell; NK) activity promotes the hepatocellular lethal effect of NK cell to contamination.Simultaneously also strengthened the T lymphocyte activity, IFN-(interferon-γ) is produced to be increased, and has promoted the expression of HLA, suppress virus replication, the diffusion of limiting virus in liver organization under the mediation of HLA (human leukocyte antigen), strengthened CD simultaneously
8Cell makes cell degeneration, swelling, dissolving and the necrosis of infective virus to infective virus cell generation perforate membrane.The patient is rehabilitated.
China is as the district occurred frequently of hepatitis B, account for global HBV surface antigen (hepatitis B virus surfaceantigen, HBsAg) nearly 50% of total carrying rate, 60% people was subjected to the infection of HBV, 8%～10% people (may surpass 1.2 hundred million) is HBsAg carrier (" medical science viruses molecule " Jin Qi chief editor, Science Press 2001), wherein there is the part hepatitis patient to develop into liver cancer; Therefore China also is the liver cancer district occurred frequently.Its treatment mainly protects the liver, and protects liver, removes virus, repairs impaired tissue.Recover the metabolic function of liver.
Third liver (hepatitis C virus, HCV): genomic high energy variability, from different areas, the gene of different crowd Different Individual isolated viral is all different.Be divided into 6 groups, more than totally 20 genotype (genotype).Be to infect by blood transfusion, its result causes the damage of liver, and its treatment is to protect the liver, to remove virus, to repair liver cell.
(hepatitis E virus, HEV) similar to hepatitis A virus, it is very popular all and causes because of pollution of waterhead and poor hygienic viral hepatitis type E.Its virus all is to enter blood through stomach and intestine, duplicates in liver cell, is discharged in blood and the bile through liver cell again.Its pathology is portal vein district inflammation, Kupffer Cell hyperplasia, ballooning degeneration of liver cells, bile capillaries cholestasis, the necrosis of liver cell focus sheet.Compound preparation mainly is that liver protecting is main for the treatment of this disease.Improve immunity.Excite activity of immune cells.Repair impaired body.
Lupus erythematosus: belong to many internal organs card marquis.It can't be drawn clearly and belong to a certain concrete illness.Be similar to " wet poison is sent out spot " of the traditional Chinese medical science, " YIN YANG toxin syndrome " " red rash " " red butterfly " etc.Involve all tissues in the whole body.Claim general arthralgia again.Because of its onset damp evil that often is affected by the cold, its morbidity is from inside to outside.With physique, heredity, sex hormone, environment, virus infections etc. are in close relations.There is 80% patient that heating paresthesia is arranged.If arthralgia appears in the invasion and attack joint.Oedema appears in the invasion and attack kidney, produces water liquid dysbolism; " hypochondriac pain " " jaundice " can appear, in the invasion and attack liver; Palpitaition acute endocarditis appears, in the invasion and attack heart.Pulmonary interstitial fibrosis the lupus pneumonia appears, in the invasion and attack lung; The lupus myasthenia appears in the invasion and attack spleen; Invasion and attack nervous system patient can have a convulsion, and is manic, anxiety, illusion, diseases such as vain hope.Taking hormone is one of main treatment means of modern medicine.In case the use hormone is difficult to control on decrement, certain side effect is arranged again, control bad can the appearance and bounce, increase the weight of the state of an illness, very then jeopardize patient's life.The normal phase makes the patient be difficult to bear pressure from each side.The present invention mainly provides a kind of safety, effectively, and the medicine that has no side effect.Can obviously strengthen patient's physique, repair the impaired dirty tissue of device, suppress the diffusion of disease, improve symptom.The application of compound preparation in treatment people AIDS-like disease hepatitis and skin diseases medicine passed through the different state of an illness, and patient's medication of all ages and classes is systematically treated, and 3 days courses of treatment, be the treatment of one-period 4 courses of treatment.
The present invention is from the characteristics of the traditional Chinese medical science " organic conception " and " diagnosis and treatment ", to remove virus, trophozyte, repair cell are main, adopt the clearing liver cholagogic of the traditional Chinese medical science, strengthening the spleen and stomach, clearing heat and detoxicating principle of reatment promoting blood circulation and removing blood stasis, carry out multisystem, many organs, conditioning comprehensively, the enhancing body immunologic function is to reach human body dynamic equilibrium.Compare with modern technologies, the present invention has following holding a little:
1, the present invention is that the medicine of also eating with a doctor is the Chinese medicine preparation of raw material, has no side effect.
2, Main Ingredients and Appearance of the present invention and pharmacology have multifunctional effect, and the medical instrument that has has liver protecting, and the medical instrument that has has the immunity of adjusting, and the function of its various medicines is directly not identical, and its multi-functional meaning is that toxin expelling, inhibition and reparation, enhancing and reconstruction develop simultaneously.
3, the present invention can obviously improve symptom, improves a poor appetite, and regains one's strength.Its instant effect, (3 days take effect), short treating period (3 days is a course of treatment), be one-period 4 courses of treatment.It has solved existing treatment acquired immune deficiency syndrome (AIDS), and the drug toxicity of viral diseases such as hepatitis is big, and the patient obeys the serious problem of afterreaction.
Annotate: health depends on inside and outside living environment.The inside and outside living environment of appropriateness is healthy guarantee.Life is in to adjust in the complex environment of continuous variation evolves oneself.Seeking the material base of repairing cell in other words is the source that biology is grown up healthy and sound and evolved.Traditional Chinese medicine is maximum to human health contribution, its most suitable body-care, prolong life, prevent disease, treatment disease.Traditional Chinese medicine is human life's philosophy; Chinese pharmacology is the guarantee that human health is evolved; Chinese medicine is the food medicine of curing the disease, and is selecting of biological 1 years food.It is deposit in vivo biochemistry and the engineering of oxidation.(the biological function that self-regeneration is arranged itself, the long energy of course of disease generation uses up, especially to the selection produce effects of food).It is not the instrument of curing the disease, and it is the demand of biological existence.
Claims (5)
1, the application of compound preparation in treatment people AIDS-like disease hepatitis and skin diseases medicine, be a kind ofly to be used for the acquired immunodeficiency syndrome that viral disease such as antiviral, treatment acquired immune deficiency syndrome (AIDS), hepatitis, skin disease and acquired immune deficiency syndrome (AIDS) occur late period and the ancillary drug that designs, it is characterized in that it is, the medicament of making by following materials of weight proportions medicine: (unit: gram)
Chinese yam 1-36 root of large-flowered skullcap 1-30 wrinkled giant hyssop 1-30 gypsum 1-60
Rde bean 1-60 dried rhizome of rehmannia 1-36 dandelion 1-90 golden cypress 1-30
Chinese caterpillar fungus 1-90 root of herbaceous peony 1-30 calamus 1-36 radix bupleuri 1-30
Corydalis tuber 1-30 courage grass 1-30 bark of official magnolia 1-30 cape jasmine 1-30
Honeysuckle 1-45 rhizoma alismatis 1-30 Radix Glycyrrhizae 1-09 plantain seed 1-30
Rhizoma atractylodis 1-30 oriental wormwood 1-30 Asian puccoon 1-30 desmodium 1-60
The stiff silkworm 1-30 of bark of ash 1-30 oldenlandia diffusa 1-36 glossy ganoderma 1---90
Capsule of weeping forsythia 1-30 cassia twig 1-1 8 ginger 1-18 date 1---90
Selfheal 1-30 Chinese violet 1-60 sweet wormwood 1-30 chrysanthemum 1-30
2, treatment according to claim 1 is a kind ofly to be used for the acquired immunodeficiency syndrome that viral disease such as antiviral, treatment acquired immune deficiency syndrome (AIDS), hepatitis, skin disease and acquired immune deficiency syndrome (AIDS) occur late period and the medicine of the supplemental treatment that designs is characterized in that said medicament is the said formulation of any pharmacy.
3, medicine according to claim 2 is characterized in that described pharmaceutical formulation is: capsule, nutrient solution, pulvis, paste, pill.
4, according to right 3 described process for preparing medicine, it is characterized in that adopting following technical process:
(1) refine:
Raw material is selected in a, discriminating.
B, the traditional Chinese medicine raw material is cut into slices.
C, with Chinese medicine crushing screening respectively.
D, will pulverize medicinal raw material, with 4～10 times, 1 ℃～100 ℃ floodings, each 1～5 hour, the lixiviate secondary merge concentrate, dry, pulverize.
E, will cut into slices glossy ganoderma and part traditional Chinese medicine, 65% ethanol that is used for 4～10 times of medicine weight soaked 7～15 days, after filtering alcohol leaching thing water was carried, according to science ratio combination formula low temperature treatment.
(2) preparation:
A, medicinal extract is added appropriate amount of starch and dextrin and alcohol leaching water extract, slip oil and the abundant mixed pelletization drying of ethanol, the encapsulated antimicrobin storehouse that checks in to steam.
B adds an amount of sweetener with the dilution of medicinal extract concentrate and makes nutrient solution, filter at low temperature (4 ℃～-2 ℃), sterilization, bottling quality inspection warehouse-in.
C adds an amount of dextrin with medicinal extract, starch, and atomized drying is made electuary, pack quality inspection warehouse-in.
5, administrated method: by 3 days courses of treatment of the principle Orally taken and externally of returning the science of channels and collaterals, be one-period 4 courses of treatment.
Method is as follows: took with 9 o'clock morning by late 9 o'clock (1).(2) take by 3 o'clock mornings and afternoon 3 o'clock.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710107133 CN101044857A (en) | 2007-05-08 | 2007-05-08 | Application of compounding preparation in medicine for treating human Aids hepatitis and skin diseases |
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|---|---|---|---|
| CN 200710107133 CN101044857A (en) | 2007-05-08 | 2007-05-08 | Application of compounding preparation in medicine for treating human Aids hepatitis and skin diseases |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695515B (en) * | 2009-11-03 | 2011-10-12 | 戴勇 | Chinese medicament for treating acquired immune deficiency syndrome and preparation method thereof |
| CN103585406A (en) * | 2013-10-28 | 2014-02-19 | 泰安市岱岳区山农高科兽药研究所 | Traditional Chinese medicine preparation for controlling poultry liver and kidney diseases |
| CN105456444A (en) * | 2015-12-03 | 2016-04-06 | 刘彩虹 | Chinese herbal preparation for treating melanoma and preparation method and application thereof |
| CN108186946A (en) * | 2018-02-10 | 2018-06-22 | 郑小眼 | It is a kind of to treat AIDS skin system Chinese medicine composition |
-
2007
- 2007-05-08 CN CN 200710107133 patent/CN101044857A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101695515B (en) * | 2009-11-03 | 2011-10-12 | 戴勇 | Chinese medicament for treating acquired immune deficiency syndrome and preparation method thereof |
| CN103585406A (en) * | 2013-10-28 | 2014-02-19 | 泰安市岱岳区山农高科兽药研究所 | Traditional Chinese medicine preparation for controlling poultry liver and kidney diseases |
| CN103585406B (en) * | 2013-10-28 | 2016-03-02 | 泰安市岱岳区山农高科兽药研究所 | A kind of Chinese medicine preparation preventing and treating poultry hepatorenal disease |
| CN105456444A (en) * | 2015-12-03 | 2016-04-06 | 刘彩虹 | Chinese herbal preparation for treating melanoma and preparation method and application thereof |
| CN108186946A (en) * | 2018-02-10 | 2018-06-22 | 郑小眼 | It is a kind of to treat AIDS skin system Chinese medicine composition |
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Application publication date: 20071003 |