CN101036795A - Method for disinfection and sterilization by hydrogen peroxide plasma - Google Patents
Method for disinfection and sterilization by hydrogen peroxide plasma Download PDFInfo
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- CN101036795A CN101036795A CN 200710039665 CN200710039665A CN101036795A CN 101036795 A CN101036795 A CN 101036795A CN 200710039665 CN200710039665 CN 200710039665 CN 200710039665 A CN200710039665 A CN 200710039665A CN 101036795 A CN101036795 A CN 101036795A
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Abstract
The invention relates to a sterilization methods using hydrogen peroxide plasma. The article to sterilize is put into a sealed container, and the inner of the sealed container becomes low pressure by the vacuum system, and then the hydrogen peroxide is injected into the sealed container by hydrogen peroxide injection device, furthermore the injected hydrogen peroxide is ionized into plasma by electrode discharging. The hydrogen peroxide plasma is full of the sealed container through diffusing action, and contacts with the article to sterilize, at a set temperature of 41-50 degree.
Description
Technical field
The present invention relates to a kind of method for disinfection and sterilization by hydrogen peroxide plasma, particularly a kind of hydrogen peroxide plasma sterilization process that can allow under certain environmental conditions reaches the method for optimum efficiency.
Background technology
In existing technology, utilization hydrogen peroxide plasma the finishing by foreign vendor exploitation of sterilizing methods that carry out disinfection, this type of sterilizing methods mainly is in low pressure (vacuum) environment ionic mediumization with hydrogen peroxide, and provide sterilization functions by this hydrogen peroxide plasma, this kind method does not need hot environment, so can be to the sterilization that carries out disinfection of more extensive medical apparatus and instruments, the time weak point that its sterilization process is required, the practical value height, it does not have drug residue after sterilization again, so safety is good, the method is a kind of splendid sterilizing methods really.
By ZL98115880.3 " a kind of high frequency low-temperature plasma sterilization sterilizing methods and equipment " and ZL 98217467.5 " a kind of high frequency low-temperature plasma sterilization bactericidal unit ", this two case is the patent that is obtained by China Science ﹠ Technology University, the device that proposes in this two patents case is to be arranged on metal cools electrode in the container and metal shell respectively as two electrodes that produce plasma, to be connected with the high frequency electric source outfan; The plasma operation material is a hydrogen peroxide; The metal cools electrode constitutes with the inner coolant of the metal tube of hollow.Though this design can reach the effect that produces low-temperature plasma, has technical difficulty on practice; In practical operation with hydrogen peroxide during as the plasma operation material, must be controlled at low temperature state to its temperature, its electrode of aforementioned patent case adopts high frequency electric source output, can produce high temperature in use, so adopted the metal cools electrode, but the personage who is familiar with this technology all can understand, it is controlled temperature with cooling method and difficult really in the practical operation its working environment is maintained within the precise dose scope, in the aforementioned patent case, also temperature or the pressure that sets is not defined again, still have its degree of difficulty on the implementation.
The inventor uses the disinfection and sterilization by hydrogen peroxide plasma technology of external exploitation, before developed the 200520045595.9th " hydrogen peroxide plasma low temperature sterilization equipment " utility model patent case, yet the environmental condition of its sterilization is not done appropriate control in this of the Ti Chuing technology abroad, when carrying out disinfection the sterilization operation, can't accurately grasp the effect that it is reached to making its equipment, modern for promoting the sterilization effect of this equipment, be to test and study, in the hope of this equipment being brought into play best sterilization effect at the terms and conditions of this method.
This type of plasma sterilizing equipment must be controlled accurately to temperature and pressure when utilization, temperature with regard to setting: then easily the article that are sterilized sterilization are produced harmful effect if temperature is too high, especially just can't be for the article of some non-refractories with the method sterilization that carries out disinfection, moreover, temperature Gao Ze needs suitable cool time after sterilization is finished, influence the whole required time of sterilization process, in addition, if it is temperature required higher, then must spend the energy of heating, consider it also is a disappearance with regard to economic angle, but then can't reach required sterilization efficacy if temperature is crossed to hang down, therefore how can find optimal temperature promptly is a considerable problem; Pressure with regard to setting again: if the excessive diffusion effect that then influences hydrogen peroxide of pressure then increases the load of equipment evacuation and directly has influence on equipment cost if pressure is too small.
Summary of the invention
Main purpose of the present invention is to seek can be for the minimum temperature and the maximum pressure value of method for disinfection and sterilization by hydrogen peroxide plasma use, that is to say that the terms and conditions that The present invention be directed to method for disinfection and sterilization by hydrogen peroxide plasma researchs and analyses, the method for the sterilization effect the best that after continuous test, draws.
Technical program of the present invention lies in: a kind of method for disinfection and sterilization by hydrogen peroxide plasma is provided, it is the method for sterilization of carrying out disinfection in the sealed container that a vacuum extractor and hydrogen peroxide injecting device are connected, in the sealing container, be assembled with an electrode that is used for hydrogen peroxide plasmaization, this method is after the article of desiring sterilization are inserted the sealing container, with vacuum extractor the sealing internal tank is pumped into low pressure, with hydrogen peroxide injecting device hydrogen peroxide is injected among the sealing container then, the hydrogen peroxide that will inject sealed container by electrode discharge is ionized into plasma again, allow hydrogen peroxide electricity plasma riddle in the sealed container by diffusion, and can contact the sterilization that carries out disinfection with the article of desiring sterilization, its design temperature scope that carries out disinfection sterilization is 41 ℃~50 ℃.
Aforementioned method for disinfection and sterilization by hydrogen peroxide plasma, its design temperature that carries out disinfection sterilization is preferably 0.5 ℃ of 45 ℃ of plus-minus.
Aforementioned method for disinfection and sterilization by hydrogen peroxide plasma, its design temperature that carries out disinfection sterilization is preferably 0.5 ℃ of 44 ℃ of plus-minus.
Aforementioned method for disinfection and sterilization by hydrogen peroxide plasma, its design temperature that carries out disinfection sterilization is preferably 0.5 ℃ of 43 ℃ of plus-minus.
Aforementioned method for disinfection and sterilization by hydrogen peroxide plasma, its design temperature that carries out disinfection sterilization is preferably 0.5 ℃ of 42 ℃ of plus-minus.
Aforesaid again method the preflood sealed container interior pressure of hydrogen peroxide be 3 the holder below negative pressure.
By method for disinfection and sterilization by hydrogen peroxide plasma of the present invention, can allow the hydrogen peroxide plasma sterilizing installation bring into play best sterilization effect.
The specific embodiment
The method for disinfection and sterilization by hydrogen peroxide plasma that the present invention proposes is a kind ofly to come the carry out disinfection method of sterilization of medical apparatus and instruments or relative article with hydrogen peroxide plasma in a sealed container, it is to be connected with vacuum extractor and hydrogen peroxide injecting device with a sealed container, in the sealing container, be assembled with simultaneously an electrode, by this can be after the desire sterilization article be inserted the sealing container, with vacuum extractor the sealing internal tank is pumped into low pressure (vacuum), with hydrogen peroxide injecting device an amount of hydrogen peroxide is injected among the sealing container then, the hydrogen peroxide that will inject sealed container by electrode discharge is ionized into plasma again, so can allow hydrogen peroxide electricity plasma riddle in the sealed container by diffusion, and can contact with the article of desiring sterilization, the sterilization effect of reaching is provided to provide.
For trying to achieve best sterilization effect, the inventor controls test at the terms and conditions of sterilization, through constantly having obtained this method of optimal conditions after the test, and can reach the sterilization effect desiring to reach in the sterilization process.
Test of the present invention at the test change condition comprise: pressure, temperature and time, rigid condition are then for the sealed container internal volume is 100 liters, the liquid hydroperoxide amount injected is that 2 milliliters, electrode are as the criterion can produce arc discharge; Each test is to contain: the stainless steel blade of 2.5*106 bacillus (Bacillus stearothermophilus) carries out biologic test, each blade of testing is to be contained in respectively in the elongated glass tubing, the length of this glass tubing is 300mm, internal diameter is 5mm, in order to suitable diffusion-restricted condition to be provided, in the results list ratio with number of blades that leaves the survival bacillus and the blade sum of testing.
Test 1
(with big pressure limit, large-spacing, large-temperature range, large-spacing are suitable for pressure and temperature is tentatively tested)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 121 holders with 1 holder, is spaced apart every 40 holders to carry out one group of test, four groups altogether;
Temperature is tested (owing to might cause user to scald more than 60 ℃, selecting 60 ℃ of upper limits for test) with 30 ℃~60 ℃ scope, is spaced apart every 5 ℃ and carries out one group of test, seven groups altogether;
The setting-up time of sterilizing is 1 hour (ideal time accepted that general hospital carries out the sterilization of instruments sterilization is in one hour);
Result of the test such as following table 1:
1 holder | 41 holders | 81 holders | 121 holders | |
30℃ | 6/6 | 6/6 | 6/6 | 6/6 |
35℃ | 6/6 | 6/6 | 6/6 | 6/6 |
40℃ | 0/6 | 6/6 | 6/6 | 6/6 |
45℃ | 0/6 | 5/6 | 6/6 | 6/6 |
50℃ | 0/6 | 6/6 | 6/6 | 6/6 |
55℃ | 0/6 | 5/6 | 6/6 | 6/6 |
60℃ | 0/6 | 6/6 | 6/6 | 6/6 |
Table 1
Conclusion (of pressure testing): design temperature is in the effect that all can't reach sterilization below 35 ℃ under various pressure conditions;
When 41 holders are above, all can't reach the effect of sterilization at the preflood sealed container interior pressure of hydrogen peroxide under all temps condition, its diffusion effect is not good, can't be for the sterilization utilization.
Test 2
(time is constant, and the pressure limit upper limit downgrades and pressure intervals is dwindled, and the temperature range lower limit increases and the temperature interval is constant tests)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 41 holders with 1 holder, is spaced apart every 10 holders to carry out one group of test, five groups altogether;
Temperature is tested with 35 ℃~60 ℃ scope, is spaced apart every 5 ℃ to carry out one group of test, six groups altogether;
The time of sterilizing is 1 hour;
Result of the test such as following table 2:
1 holder | 11 holders | 21 holders | 31 holders | 41 holders | |
35℃ | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
40℃ | 0/6 | 6/6 | 6/6 | 6/6 | 6/6 |
45℃ | 0/6 | 6/6 | 6/6 | 6/6 | 6/6 |
50℃ | 0/6 | 6/6 | 6/6 | 6/6 | 6/6 |
55℃ | 0/6 | 6/6 | 6/6 | 6/6 | 6/6 |
60℃ | 0/6 | 6/6 | 6/6 | 6/6 | 6/6 |
Table 2
Conclusion (of pressure testing): design temperature is 35 ℃ of effects that all can't reach sterilization under various pressure conditions;
When 11 holders are above, all can't reach the effect of sterilization at the preflood sealed container interior pressure of hydrogen peroxide under all temps condition, its diffusion effect is not good, can't be for the sterilization utilization.
Test 3
(temperature, time are constant, in littler pressure limit and dwindle pressure intervals and test)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 11 holders with 1 holder, is spaced apart every 2 holders to carry out one group of test, six groups altogether;
Temperature is tested with 35 ℃~60 ℃ scope, is spaced apart every 5 ℃ to carry out one group of test, six groups altogether;
The time of sterilizing is 1 hour;
Result of the test such as following table 3:
1 holder | 3 holders | 5 holders | 7 holders | 9 holders | 11 holders | |
35℃ | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
40℃ | 0/6 | 0/6 | 5/6 | 6/6 | 6/6 | 6/6 |
45℃ | 0/6 | 0/6 | 5/6 | 6/6 | 6/6 | 6/6 |
50℃ | 0/6 | 0/6 | 2/6 | 6/6 | 6/6 | 6/6 |
55℃ | 0/6 | 0/6 | 3/6 | 6/6 | 6/6 | 6/6 |
60℃ | 0/6 | 0/6 | 4/6 | 6/6 | 6/6 | 6/6 |
Table 3
Conclusion (of pressure testing): design temperature is 35 ℃ of effects that all can't reach sterilization under various pressure conditions;
When 5 holders are above, all can't reach the effect of sterilization at the preflood sealed container interior pressure of hydrogen peroxide under all temps condition, its diffusion effect is not good, can't be for the sterilization utilization.
Test 4
(temperature, time are constant, dwindle pressure intervals in low-pressure scope more and test)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 5 holders with 1 holder, is spaced apart every 1 holder to carry out one group of test, five groups altogether;
Temperature is tested with 35 ℃~60 ℃ scope, is spaced apart every 5 ℃ to carry out one group of test, six groups altogether;
The time of sterilizing is 1 hour;
Result of the test such as following table 4:
1 holder | 2 holders | 3 holders | 4 holders | 5 holders | |
35℃ | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
40℃ | 0/6 | 0/6 | 0/6 | 1/6 | 2/6 |
45℃ | 0/6 | 0/6 | 0/6 | 0/6 | 2/6 |
50℃ | 0/6 | 0/6 | 0/6 | 1/6 | 1/6 |
55℃ | 0/6 | 0/6 | 0/6 | 0/6 | 1/6 |
60℃ | 0/6 | 0/6 | 0/6 | 0/6 | 3/6 |
Table 4
Conclusion (of pressure testing): design temperature is 35 ℃ of effects that all can't reach sterilization under various pressure conditions;
When 4 holders are above, sterilization incomplete result respectively occur at 40 ℃ and 50 ℃ at the preflood sealed container interior pressure of hydrogen peroxide, its diffusion effect is not good, can't be for the sterilization utilization.
Test 5
(time is constant, dwindles pressure limit between 1 holder is held in the palm to 4, dwindles the temperature interval in littler temperature range and tests)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 4 holders with 1 holder, is spaced apart every 1 holder to carry out one group of test, four groups altogether;
Temperature is tested with 36 ℃~60 ℃ scope, is spaced apart every 4 ℃ to carry out one group of test, seven groups altogether;
The time of sterilizing is 1 hour;
Result of the test such as following table 5:
1 holder | 2 holders | 3 holders | 4 holders | |
36℃ | 6/6 | 6/6 | 6/6 | 6/6 |
40℃ | 0/6 | 0/6 | 0/6 | 0/6 |
44℃ | 0/6 | 0/6 | 0/6 | 0/6 |
48℃ | 0/6 | 0/6 | 0/6 | 0/6 |
52℃ | 0/6 | 0/6 | 0/6 | 0/6 |
56℃ | 0/6 | 0/6 | 0/6 | 0/6 |
60℃ | 0/6 | 0/6 | 0/6 | 0/6 |
Table 5
Conclusion (of pressure testing): design temperature is 36 ℃ of effects that all can't reach sterilization under various pressure conditions;
Under each pressure condition, all can finish the sterilization effect in each temperature interval more than 40 ℃.
Test 6
(pressure is constant, dwindles the temperature interval in littler temperature range and tests)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 4 holders with 1 holder, is spaced apart every 1 holder to carry out one group of test, four groups altogether;
Temperature is tested with 37 ℃~40 ℃ scope, is spaced apart every 1 ℃ to carry out one group of test, four groups altogether;
The time of sterilizing is 1 hour;
Result of the test such as following table 6:
1 holder | 2 holders | 3 holders | 4 holders | |
37℃ | 5/6 | 6/6 | 5/6 | 6/6 |
38℃ | 6/6 | 6/6 | 6/6 | 6/6 |
39℃ | 6/6 | 6/6 | 4/6 | 6/6 |
40℃ | 0/6 | 0/6 | 1/6 | 3/6 |
Table 6
Conclusion (of pressure testing): design temperature is in the effect that all can't reach sterilization below 39 ℃ under various pressure conditions;
At 40 ℃ of pressure is can't reach sterilization effect under 3~4 holder conditions;
Test 7
(pressure, time are constant, adjust temperature range and test)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 4 holders with 1 holder, is spaced apart every 1 holder to carry out one group of test, four groups altogether;
Temperature is tested with 40 ℃~43 ℃ scope, is spaced apart every 1 ℃ to carry out one group of test, four groups altogether;
The time of sterilizing is 1 hour;
Result of the test such as following table 7:
1 holder | 2 holders | 3 holders | 4 holders | |
40℃ | 0/6 | 0/6 | 0/6 | 5/6 |
41℃ | 0/6 | 0/6 | 0/6 | 2/6 |
42℃ | 0/6 | 0/6 | 0/6 | 2/6 |
43℃ | 0/6 | 0/6 | 0/6 | 3/6 |
Table 7
Conclusion (of pressure testing): design temperature is the effect that all can arrive sterilization under the 3 holder conditions at 40 ℃~43 ℃ at pressure;
Design temperature is all can't reach sterilization effect under the 4 holder conditions at 40 ℃~43 ℃ at pressure;
Test 8
(pressure is constant, adjusts temperature range, and the shortening time tests)
The preflood sealed container interior pressure of hydrogen peroxide is tested to the negative pressure of 4 holders with 1 holder, is spaced apart every 1 holder to carry out one group of test, four groups altogether;
Temperature is tested with 40 ℃~50 ℃ scope, is spaced apart every 1 ℃ to carry out one group of test, 11 groups altogether;
The time of sterilizing is 50 minutes;
Result of the test such as following table 8:
1 holder | 2 holders | 3 holders | 4 holders | |
40℃ | 4/6 | 4/6 | 4/6 | 3/6 |
41℃ | 4/6 | 2/6 | 4/6 | 6/6 |
42℃ | 0/6 | 0/6 | 2/6 | 3/6 |
43℃ | 0/6 | 0/6 | 1/6 | 5/6 |
44℃ | 0/6 | 0/6 | 1/6 | 5/6 |
45℃ | 0/6 | 0/6 | 0/6 | 6/6 |
46℃ | 0/6 | 0/6 | 0/6 | 4/6 |
47℃ | 0/6 | 0/6 | 0/6 | 5/6 |
48℃ | 0/6 | 0/6 | 0/6 | 3/6 |
49℃ | 0/6 | 0/6 | 0/6 | 4/6 |
50℃ | 0/6 | 0/6 | 0/6 | 2/6 |
Table 8
Conclusion (of pressure testing): design temperature is 50 minutes at 40 ℃ and 41 ℃ in the sterilization time, all can't reach the effect of sterilization under various pressure conditions;
Is 50 minutes at 42 ℃~44 ℃ in the sterilization time, and pressure is can't reach sterilization effect under 3 holders~4 holder conditions;
Each temperature interval more than 45 ℃ in the sterilization time be 50 minutes pressure be 3 the holder below condition under all can finish the sterilization effect.
By above Test Summary, method for disinfection and sterilization by hydrogen peroxide plasma of the present invention is that 3 holders are when following at the preflood sealed container interior pressure of hydrogen peroxide, sterilization effect under each design temperature condition has notable difference, result by test 6,7, temperature conditions should be more than 41 ℃, result by test 8, the time be 50 minutes constantly in the effect that can reach sterilization more than 45 ℃, based on security consideration, add temperature controlled accuracy consideration, in practical operation, can select 45 ℃ to be optimum temperature; In addition since the temperature more than 45 ℃ for sterilization effect no significant difference based on safety in utilization (avoid scalding and to the harmful effect of sterilization article) and energy savings and reduce cool time, so its temperature range upper limit is set in 50 ℃
Method for disinfection and sterilization by hydrogen peroxide plasma of the present invention again in aforementioned optimum temperature range, the preflood sealed container interior pressure of hydrogen peroxide be 3 the holder below negative pressure under can reach desired sterilization effect.
The present invention is directed to the method for disinfection and sterilization by hydrogen peroxide plasma of developing abroad and carry out more deep research, after constantly testing, draw best temperature range, and allow the method in utilization, can obtain more perfect sterilization effect.
Claims (10)
1, a kind of method for disinfection and sterilization by hydrogen peroxide plasma, it is the method for sterilization of carrying out disinfection in the sealed container that a vacuum extractor and hydrogen peroxide injecting device are connected, in the sealing container, be assembled with an electrode that is used for hydrogen peroxide plasmaization, this method is after the article of desiring sterilization are inserted the sealing container, with vacuum extractor the sealing internal tank is pumped into low pressure, with hydrogen peroxide injecting device hydrogen peroxide is injected among the sealing container then, the hydrogen peroxide that will inject sealed container by electrode discharge is ionized into plasma again, allow hydrogen peroxide electricity plasma riddle in the sealed container by diffusion, and can contact the sterilization that carries out disinfection with the article of desiring sterilization, it is characterized in that: the design temperature scope of the sterilization that carries out disinfection is 41 ℃~50 ℃.
2, method for disinfection and sterilization by hydrogen peroxide plasma according to claim 1 is characterized in that: the preflood sealed container interior pressure of hydrogen peroxide be 3 the holder below negative pressure.
3, a kind of method for disinfection and sterilization by hydrogen peroxide plasma, it is the method for sterilization of carrying out disinfection in the sealed container that a vacuum extractor and hydrogen peroxide injecting device are connected, in the sealing container, be assembled with an electrode that is used for hydrogen peroxide plasmaization, this method is after the article of desiring sterilization are inserted the sealing container, with vacuum extractor the sealing internal tank is pumped into low pressure, with hydrogen peroxide injecting device hydrogen peroxide is injected among the sealing container then, the hydrogen peroxide that will inject sealed container by electrode discharge is ionized into plasma again, allow hydrogen peroxide electricity plasma riddle in the sealed container by diffusion, and can contact the sterilization that carries out disinfection with the article of desiring sterilization, it is characterized in that: the design temperature of the sterilization that carries out disinfection is 0.5 ℃ of 45 ℃ of plus-minus.
4, method for disinfection and sterilization by hydrogen peroxide plasma according to claim 3 is characterized in that: the preflood sealed container interior pressure of hydrogen peroxide be 3 the holder below negative pressure.
5, a kind of method for disinfection and sterilization by hydrogen peroxide plasma, it is the method for sterilization of carrying out disinfection in the sealed container that a vacuum extractor and hydrogen peroxide injecting device are connected, in the sealing container, be assembled with an electrode that is used for hydrogen peroxide plasmaization, this method is after the article of desiring sterilization are inserted the sealing container, with vacuum extractor the sealing internal tank is pumped into low pressure, with hydrogen peroxide injecting device hydrogen peroxide is injected among the sealing container then, the hydrogen peroxide that will inject sealed container by electrode discharge is ionized into plasma again, allow hydrogen peroxide electricity plasma riddle in the sealed container by diffusion, and can contact the sterilization that carries out disinfection with the article of desiring sterilization, it is characterized in that: the design temperature of the sterilization that carries out disinfection is 0.5 ℃ of 44 ℃ of plus-minus.
6, method for disinfection and sterilization by hydrogen peroxide plasma according to claim 5 is characterized in that: the preflood sealed container interior pressure of hydrogen peroxide be 3 the holder below negative pressure.
7, a kind of method for disinfection and sterilization by hydrogen peroxide plasma, it is the method for sterilization of carrying out disinfection in the sealed container that a vacuum extractor and hydrogen peroxide injecting device are connected, in the sealing container, be assembled with an electrode that is used for hydrogen peroxide plasmaization, this method is after the article of desiring sterilization are inserted the sealing container, with vacuum extractor the sealing internal tank is pumped into low pressure, with hydrogen peroxide injecting device hydrogen peroxide is injected among the sealing container then, the hydrogen peroxide that will inject sealed container by electrode discharge is ionized into plasma again, allow hydrogen peroxide electricity plasma riddle in the sealed container by diffusion, and can contact the sterilization that carries out disinfection with the article of desiring sterilization, it is characterized in that: the design temperature of the sterilization that carries out disinfection is 0.5 ℃ of 43 ℃ of plus-minus.
8, method for disinfection and sterilization by hydrogen peroxide plasma according to claim 7 is characterized in that: the preflood sealed container interior pressure of hydrogen peroxide be 3 the holder below negative pressure.
9, a kind of method for disinfection and sterilization by hydrogen peroxide plasma, it is the method for sterilization of carrying out disinfection in the sealed container that a vacuum extractor and hydrogen peroxide injecting device are connected, in the sealing container, be assembled with an electrode that is used for hydrogen peroxide plasmaization, this method is after the article of desiring sterilization are inserted the sealing container, with vacuum extractor the sealing internal tank is pumped into low pressure, with hydrogen peroxide injecting device hydrogen peroxide is injected among the sealing container then, the hydrogen peroxide that will inject sealed container by electrode discharge is ionized into plasma again, allow hydrogen peroxide electricity plasma riddle in the sealed container by diffusion, and can contact the sterilization that carries out disinfection with the article of desiring sterilization, it is characterized in that: the design temperature of the sterilization that carries out disinfection is 0.5 ℃ of 42 ℃ of plus-minus.
10, method for disinfection and sterilization by hydrogen peroxide plasma according to claim 9 is characterized in that: the preflood sealed container interior pressure of hydrogen peroxide be 3 the holder below negative pressure.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103071166A (en) * | 2013-01-29 | 2013-05-01 | 连云港佑源医药设备制造有限公司 | Sterilization method of surgical device and anesthetic catheter |
WO2013127041A1 (en) * | 2012-03-01 | 2013-09-06 | 北京白象新技术有限公司 | Hydrogen peroxide injection device for rotating-disc-type low-temperature plasma sterilizer |
CN113577337A (en) * | 2014-12-22 | 2021-11-02 | 蓝波技术公司 | Plasma processing apparatus and article processing method |
-
2007
- 2007-04-19 CN CN 200710039665 patent/CN101036795A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013127041A1 (en) * | 2012-03-01 | 2013-09-06 | 北京白象新技术有限公司 | Hydrogen peroxide injection device for rotating-disc-type low-temperature plasma sterilizer |
CN103071166A (en) * | 2013-01-29 | 2013-05-01 | 连云港佑源医药设备制造有限公司 | Sterilization method of surgical device and anesthetic catheter |
CN103071166B (en) * | 2013-01-29 | 2015-01-28 | 连云港佑源医药设备制造有限公司 | Sterilization method of surgical device and anesthetic catheter |
CN113577337A (en) * | 2014-12-22 | 2021-11-02 | 蓝波技术公司 | Plasma processing apparatus and article processing method |
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Application publication date: 20070919 |