CN101033237A - Medicinal disodium creatine phosphate hexahydrate and preparing method thereof - Google Patents
Medicinal disodium creatine phosphate hexahydrate and preparing method thereof Download PDFInfo
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- CN101033237A CN101033237A CN 200710038838 CN200710038838A CN101033237A CN 101033237 A CN101033237 A CN 101033237A CN 200710038838 CN200710038838 CN 200710038838 CN 200710038838 A CN200710038838 A CN 200710038838A CN 101033237 A CN101033237 A CN 101033237A
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- phosphoric acid
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- creatinine
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CNB200710038838XA CN100488968C (en) | 2007-03-30 | 2007-03-30 | Medicinal disodium creatine phosphate hexahydrate and preparing method thereof |
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CNB200710038838XA CN100488968C (en) | 2007-03-30 | 2007-03-30 | Medicinal disodium creatine phosphate hexahydrate and preparing method thereof |
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CN101033237A true CN101033237A (en) | 2007-09-12 |
CN100488968C CN100488968C (en) | 2009-05-20 |
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Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101723972A (en) * | 2008-10-21 | 2010-06-09 | 上海奇成化工科技发展有限公司 | Method for extracting croatine phosphate disodium salt from reaction solution |
CN101812088A (en) * | 2010-03-19 | 2010-08-25 | 海南美大制药有限公司 | High-purity creatine phosphate sodium compound |
CN101492470B (en) * | 2008-01-22 | 2012-01-11 | 上海慈瑞医药科技有限公司 | Synthesis of phosphocreatine disodium salt |
CN102558227A (en) * | 2011-12-29 | 2012-07-11 | 中山百灵生物技术有限公司 | Novel method for preparing high-purity creatine phosphate sodium |
CN102633833A (en) * | 2012-04-06 | 2012-08-15 | 南京臣功制药股份有限公司 | Creatine phosphate sodium preparation method |
CN102690285A (en) * | 2011-03-24 | 2012-09-26 | 重庆莱美药业股份有限公司 | Preparation method of disodium creatine phosphate |
CN102702253A (en) * | 2012-03-23 | 2012-10-03 | 上海龙翔生物医药开发有限公司 | Method for preparing high-content creatine phosphate disodium salt |
CN103204875A (en) * | 2013-04-25 | 2013-07-17 | 孙威 | Creatine phosphate sodium compound and preparation method thereof |
CN103242364A (en) * | 2012-12-28 | 2013-08-14 | 开封明仁药业有限公司 | Creatine phosphate sodium preparation method |
CN104109171A (en) * | 2013-04-19 | 2014-10-22 | 上海和臣医药工程有限公司 | Disodium N-[imino(phosphinoamino)methyl]-N-methylglycinate hydrate and preparation method thereof |
CN104530120A (en) * | 2014-12-30 | 2015-04-22 | 哈尔滨莱博通药业有限公司 | Creatine phosphate sodium compound and crystal form thereof |
CN105294768A (en) * | 2015-10-26 | 2016-02-03 | 上海华拓医药科技发展有限公司 | Phosphocreatine compound and application thereof |
CN106279267A (en) * | 2015-05-20 | 2017-01-04 | 重庆圣华曦药业股份有限公司 | The purification process of a kind of Creatine Phosphate Sodium and the preparation of aseptic powder thereof |
CN107501320A (en) * | 2017-08-03 | 2017-12-22 | 江苏汉斯通药业有限公司 | The preparation method of Creatine Phosphate Sodium |
CN110294775A (en) * | 2018-03-23 | 2019-10-01 | 安徽古特生物科技有限公司 | A kind of purification process of Creatine Phosphate Sodium |
CN111777636A (en) * | 2020-07-09 | 2020-10-16 | 山东罗欣药业集团股份有限公司 | Preparation method of medicine for protecting cardiac muscle |
-
2007
- 2007-03-30 CN CNB200710038838XA patent/CN100488968C/en active Active
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101492470B (en) * | 2008-01-22 | 2012-01-11 | 上海慈瑞医药科技有限公司 | Synthesis of phosphocreatine disodium salt |
CN101723972A (en) * | 2008-10-21 | 2010-06-09 | 上海奇成化工科技发展有限公司 | Method for extracting croatine phosphate disodium salt from reaction solution |
CN101812088A (en) * | 2010-03-19 | 2010-08-25 | 海南美大制药有限公司 | High-purity creatine phosphate sodium compound |
CN101812088B (en) * | 2010-03-19 | 2012-09-26 | 海南美大制药有限公司 | High-purity creatine phosphate sodium compound |
CN102690285B (en) * | 2011-03-24 | 2014-12-24 | 重庆莱美药业股份有限公司 | Preparation method of disodium creatine phosphate |
CN102690285A (en) * | 2011-03-24 | 2012-09-26 | 重庆莱美药业股份有限公司 | Preparation method of disodium creatine phosphate |
CN102558227A (en) * | 2011-12-29 | 2012-07-11 | 中山百灵生物技术有限公司 | Novel method for preparing high-purity creatine phosphate sodium |
CN102558227B (en) * | 2011-12-29 | 2015-01-28 | 中山百灵生物技术有限公司 | Novel method for preparing high-purity creatine phosphate sodium |
CN102702253B (en) * | 2012-03-23 | 2015-09-02 | 上海龙翔生物医药开发有限公司 | The preparation method of high-content disodium creatine phosphate |
CN102702253A (en) * | 2012-03-23 | 2012-10-03 | 上海龙翔生物医药开发有限公司 | Method for preparing high-content creatine phosphate disodium salt |
CN102633833A (en) * | 2012-04-06 | 2012-08-15 | 南京臣功制药股份有限公司 | Creatine phosphate sodium preparation method |
CN102633833B (en) * | 2012-04-06 | 2014-10-29 | 南京臣功制药股份有限公司 | Creatine phosphate sodium preparation method |
CN103242364A (en) * | 2012-12-28 | 2013-08-14 | 开封明仁药业有限公司 | Creatine phosphate sodium preparation method |
CN103242364B (en) * | 2012-12-28 | 2016-03-23 | 开封明仁药业有限公司 | The preparation method of Disodium phosphocreatine |
CN104109171A (en) * | 2013-04-19 | 2014-10-22 | 上海和臣医药工程有限公司 | Disodium N-[imino(phosphinoamino)methyl]-N-methylglycinate hydrate and preparation method thereof |
CN104109171B (en) * | 2013-04-19 | 2017-02-08 | 上海华拓医药科技发展有限公司 | Disodium N-[imino(phosphinoamino)methyl]-N-methylglycinate hydrate and preparation method thereof |
CN103204875B (en) * | 2013-04-25 | 2015-04-08 | 孙威 | Creatine phosphate sodium compound and preparation method thereof |
CN103204875A (en) * | 2013-04-25 | 2013-07-17 | 孙威 | Creatine phosphate sodium compound and preparation method thereof |
CN104530120A (en) * | 2014-12-30 | 2015-04-22 | 哈尔滨莱博通药业有限公司 | Creatine phosphate sodium compound and crystal form thereof |
CN106279267A (en) * | 2015-05-20 | 2017-01-04 | 重庆圣华曦药业股份有限公司 | The purification process of a kind of Creatine Phosphate Sodium and the preparation of aseptic powder thereof |
CN106279267B (en) * | 2015-05-20 | 2018-03-13 | 重庆圣华曦药业股份有限公司 | A kind of purification process of Creatine Phosphate Sodium and its preparation of aseptic powder |
CN105294768A (en) * | 2015-10-26 | 2016-02-03 | 上海华拓医药科技发展有限公司 | Phosphocreatine compound and application thereof |
CN105294768B (en) * | 2015-10-26 | 2017-06-16 | 上海华拓医药科技发展有限公司 | Phosphocreatine class compound and its application |
CN107501320A (en) * | 2017-08-03 | 2017-12-22 | 江苏汉斯通药业有限公司 | The preparation method of Creatine Phosphate Sodium |
CN110294775A (en) * | 2018-03-23 | 2019-10-01 | 安徽古特生物科技有限公司 | A kind of purification process of Creatine Phosphate Sodium |
CN110294775B (en) * | 2018-03-23 | 2021-11-26 | 安徽古特生物科技有限公司 | Purification method of creatine phosphate sodium |
CN111777636A (en) * | 2020-07-09 | 2020-10-16 | 山东罗欣药业集团股份有限公司 | Preparation method of medicine for protecting cardiac muscle |
CN111777636B (en) * | 2020-07-09 | 2023-06-16 | 山东罗欣药业集团股份有限公司 | Preparation method of medicine for myocardial protection |
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Publication number | Publication date |
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CN100488968C (en) | 2009-05-20 |
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Assignee: QIDONG HUATUO PHARMACEUTICAL CO., LTD. Assignor: Shanghai Huatuo Medical Science Co., Ltd. Contract record no.: 2011310000024 Denomination of invention: Medicinal disodium creatine phosphate hexahydrate and preparing method thereof Granted publication date: 20090520 License type: Exclusive License Open date: 20070912 Record date: 20110323 |
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Assignee: QIDONG HUATUO PHARMACEUTICAL CO., LTD. Assignor: Shanghai Huatuo Medical Science Co., Ltd. Contract record no.: 2011310000024 Date of cancellation: 20140508 |
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Application publication date: 20070912 Assignee: Haikou Qili Pharmaceutical Co., Ltd. Assignor: Shanghai Huatuo Medical Science Co., Ltd. Contract record no.: 2014310000099 Denomination of invention: Medicinal disodium creatine phosphate hexahydrate and preparing method thereof Granted publication date: 20090520 License type: Common License Record date: 20140528 |
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Application publication date: 20070912 Assignee: QIDONG HUATUO PHARMACEUTICAL CO., LTD. Assignor: Shanghai Huatuo Medical Science Co., Ltd. Contract record no.: 2014310000108 Denomination of invention: Medicinal disodium creatine phosphate hexahydrate and preparing method thereof Granted publication date: 20090520 License type: Common License Record date: 20140619 |
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Owner name: SHANGHAI HUATUO MEDICINE SCI-TECH DEVELOPMENT CO., Free format text: FORMER NAME: SHANGHAI HUATUO MEDICAL SCIENCE CO., LTD. |
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Address after: 200093 No. 90, Shulan Road, Shanghai, Yangpu District Patentee after: Shanghai Huatuo Medicine Sci-Tech Development Co., Ltd. Address before: 200093 No. 90, Shulan Road, Shanghai, Yangpu District Patentee before: Shanghai Huatuo Medical Science Co., Ltd. |
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Application publication date: 20070912 Assignee: HARBIN LAIBOTEN PHARMACEUTICAL CO., LTD. Assignor: Shanghai Huatuo Medicine Sci-Tech Development Co., Ltd. Contract record no.: 2015310000070 Denomination of invention: Medicinal disodium creatine phosphate hexahydrate and preparing method thereof Granted publication date: 20090520 License type: Common License Record date: 20150629 |
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Effective date of registration: 20210415 Address after: 226200 No.88 Jiangsu Road, Beixin fine chemical industry park, Qidong City, Nantong City, Jiangsu Province Patentee after: QIDONG HUATUO PHARMACEUTICAL Co.,Ltd. Address before: 200093 No. 90, Shulan Road, Shanghai, Yangpu District Patentee before: SHANGHAI HOTMED SCIENCES Co.,Ltd. |
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