CN101001663A - A process of manufacturing an electrical lead - Google Patents
A process of manufacturing an electrical lead Download PDFInfo
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- CN101001663A CN101001663A CN 200580026483 CN200580026483A CN101001663A CN 101001663 A CN101001663 A CN 101001663A CN 200580026483 CN200580026483 CN 200580026483 CN 200580026483 A CN200580026483 A CN 200580026483A CN 101001663 A CN101001663 A CN 101001663A
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- elongated member
- electric
- lead
- electroconductive binder
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Abstract
A process for manufacturing an electrical lead (10) having one or more electrodes (11) includes providing an elongate member (14) having at least one polymeric region and further having at least one electrical conductor (13) that extends along at least a part of a length of the elongate member (14) and that is contained in a wall of the elongate member. A length of the at least one electrical conductor (13) is accessed at the at least one polymeric region (34). An electrically conductive adhesive (15) is applied to the length of the at least one electrical conductor (13) that has been accessed.
Description
The cross reference of related application
The application requires the U.S. Provisional Patent Application 60/599,651 submitted on August 5th, 2004 and the priority of the U.S. Provisional Patent Application 60/648,232 submitted on January 28th, 2005.
Technical field
The present invention relates to the manufacturing of electric lead, and relate more specifically to be used to make the method for electric lead (for example electrically conductive conduits), and relate to electric lead.
Background technology
The whole show of the electrical activity guiding heart of the muscle in heart.A lot of heart faults especially arrhythmia by the electrical activity proof of the normal function that is not suitable for heart or cause.Electric lead described herein is in the detection of cardiac electrical activity and be useful by stimulating, melt in the cardiac treatment with defibrillation.
Electric lead with electrode zone has been used for example and has used as previously mentioned in medical field.
Traditionally, the electrode by the metal or the winding line (coiled wire) of machining are made though it has essential electrical conductivity, can not be provided at the flexibility of needed expected degree in the medical applications.
Though considered use washing or metal filled polymer as medical-treatment electrode, the amount of metal that the electrical conductivity of acquisition proper level needs causes the lead that obtains harder, and not too is suitable for being implanted among the patient.
Summary of the invention
According to a first aspect of the invention, provide the method that is used to make the electric lead with one or more electrodes, this method comprises:
Elongated member is provided, and it has at least one polymer areas and further has at least one electric conductor, and it extends to small part along a length of described elongated member, and is contained in the wall of this elongated member;
Insert (access) length at least one electric conductor at least one polymer areas place; And
Apply the described length of electroconductive binder at least one electric conductor that has been access in.
One or more discrete electrodes can form along a length of this elongated member.Electrode can comprise to the band of small part around the circumferential extension of this elongated member.
Electroconductive binder can comprise the bonding base that is derived from the intrinsic conduction binding agent, comprises the solid conduction implant, comprise multiple material any of the bonding base that dissolves conductive material and these mixtures of material.The bonding base that comprises curable or coagulable polymeric material also is applicable to this purpose, and described polymeric material for example is not clamminess or viscid polymer after solidifying or solidifying.The epoxy resin that comprises microgranular or fibrous metal is suitable selection, the metal of the bio-compatible of especially high conduction, for example silver, gold, platinum, palladium, rhodium and their mixture, and comprise these metals and by the alloy of these metal construction in zone with heterogeneity.A selection can comprise silver-colored filling epoxy resin.
Can carry out another step that at least a conductive material is applied to electroconductive binder.Again, conductive material can be any of multiple material, but especially suitable be that those can and be arranged in the material that forms conductive layer between any other material outside this at least a conductive material at electroconductive binder.
These a kind of adequate types that will be applied in the conductive material of binding agent can be a kind of liquid carrier, especially volatility (volatile) carriers, for example differently comprise solvation or synthetic (complexed) conductor or comprise the solvent of solid conductor.The subclass of these materials can be to comprise particulate conducting metal, alloy or structure example as silver or be coated with the China ink of the silver of metal (as platinum or palladium).
Electroconductive binder or the conductive material that is applied to this electroconductive binder can further be coated with for example aforesaid conducting metal in the above.This metal can comprise platinum.
This elongated member can comprise a plurality of electric conductors, and this method can comprise each a length of a plurality of electric conductors at the interval that the circumference of access around this elongated member separates, and the liner (pad) of electroconductive binder is applied to the length that each electric conductor is access in.
This method can comprise that each liner to the electric conductor binding agent applies the layer of at least a conductive material.In addition, this method can comprise that utilization comprises platinum or palladic metal level covers on each liner of electroconductive binder.
The liner of this electroconductive binder can be arranged in around the circumference of elongated member with vertical alignment relation, and this method applies described metal level as pantostrat around can being included in the circumference of elongated member, and afterwards, for example this layer is separated into a plurality of electric insulation sections of arranging at interval that circumference separates, with a plurality of discrete electrodes of the circumference arranged around that is formed on this elongated member by cut.
This method can comprise by installing ring on elongated member and ring is fixed to correct position and applies the metal that comprises platinum.This ring can fix by binding agent, curl (crimping) or the like.
Electric lead can comprise a plurality of conductors to the small part extension along a length of this electric lead.Though one or more conductors can specifically be associated with electrode, this electric lead can comprise the other conductor of the part of formation temperature inductive means.The temperature sense parts can be associated with electrode by this way, and it determines the temperature at described electrode place.In order to determine the temperature at described electrode place, these temperature sense parts can be from the counter electrode electric insulation.
Therefore, this method can comprise the electric contact of electric lead another step from described one or more electrode insulations.This electric contact can be by with the insulation of getting off:
Insert described electric contact;
The first electric contact is applied electroconductive binder; And
This electroconductive binder of electrochemical treatments makes the part of this electroconductive binder be converted into non-conducting portion.
Electrochemical treatments can comprise makes the step of electric current by electric contact, electric current also passes through electroconductive binder like this, this electroconductive binder is in ionic environment simultaneously, and this ionic environment comprises intention and forms the material of insulator (or resistive formation) with some compositions of electric contact.The ionic environment that comprises salt (NaCl) solution or Klorvess Liquid can be suitable, though other such materials also can be considered.
Such step will be in electroconductive binder electrochemical metal be converted to metal chloride.Comprise the place of silver-colored filling epoxy resin at electroconductive binder, the lip-deep silver that is positioned in the face of solution surface is converted into silver chloride.This silver chloride layer can play the effect of insulating barrier.
Electric contact can comprise for example part of thermocouple of temperature sense parts.
According to a second aspect of the invention, provide the first electric contact of the electric lead method from the second electric contact electric insulation of electric lead, this method comprises:
Insert the first electric contact;
This first electric contact is applied electroconductive binder; And
This electroconductive binder of electrochemical treatments makes the part of this electroconductive binder be converted into non-conducting portion.
Electrochemical treatments can comprise makes the step of electric current by electric contact, and make thus electric current by electroconductive binder to form insulator.Be similar to above step, this step can be implemented in comprising the ionic environment of active material, to produce insulator or highly resistant material.Contain in the situation of ag material in selection, salt (NaCl) solution or Klorvess Liquid can be suitable.
Electroconductive binder can comprise listed above those, comprise silver-colored filling adhesive, for example silver-colored filling epoxy resin.Again, if select like this, the silver in the part of binding agent can use electrochemical reaction step discussed above to be converted to silver chloride (AgCl).The silver chloride that forms is nonconducting.
The first electric contact can comprise the temperature sense parts.
The second electric contact can comprise the power transfer electrode.This electrode can be transmitted in electrode and be arranged near the energy that forms heat in its tissue that uses.
These temperature sense parts can be in the thermo-contact with the power transfer electrode.
Temperature sense parts in this modification and other situations described herein can comprise occasionally other temperature sensing devices of thermoelectricity, for example RTD, electro-hot regulator or IC device, the output in its medium frequency or cycle and temperature correlation.If selected thermocouple, then the suitable selection of conductor can comprise first electric wire that is made of copper and second electric wire of being made by constantan.
Electric lead can comprise such elongated member, and wherein the electric wire of thermocouple is along the extending to small part an of length of elongated member, and can be accommodated in the wall of this elongated member.Contact (junction) can be formed between two electric wires of the thermocouple that inserts electrode, with by this electric wire is applied electroconductive binder, forms the closed loop heat galvanic couple, so that electric wire is electrically connected each other at this contact place.
At least a conductive material can be applied on electrode and the thermal cross.
Broadly, according to a third aspect of the invention we, provide the method for making electric lead, this method comprises:
Elongated member is provided, it has near-end and far-end, at least one electric conductor, this electric conductor be contained in this elongated member and from the near-end of elongated member towards remote extension, this at least one electric conductor with the middle termination that is electrically connected that is arranged in conduction region outside the elongated member;
Cut-out is away from the elongated member of this conduction region;
Form non-conductive terminal away from this conduction region; And
On this conduction region and described terminal, apply conductive material, to form the termination electrode of electric lead.
More specifically, according to a third aspect of the invention we, provide the method for making electric lead, this method comprises:
Elongated member is provided, it has near-end and far-end, this elongated member has one or more polymer areas, and have a plurality of electric conductors in addition, these a plurality of electric conductors are along the remote extension to small part towards this elongated member of a length of this elongated member, and this electric conductor is accommodated in the wall of this elongated member;
For at least some of this electric conductor each, form and the electric conduction region that contacts of its electric conductor that is associated by following steps:
Polyidal field by elongated member inserts each a length of at least some electric conductors, and the electric conductor of each access is applied electroconductive binder;
Apply conductive material at the access point place that is associated with each electric conductor, form a plurality of conduction regions that vertically separate with length along this elongated member;
Cut-out is away from the elongated member of one of conduction region;
Apply non-conductive terminal away from a conduction region; And
Use conductive material and come bridge joint conduction region and terminal, to form the termination electrode of elongated member.
Terminal can apply under liquid state.This terminal can divide two stages to apply.
Therefore, ground floor can be used for sealing the far-end of elongated member.The second layer can be used and be shaped provide intended shape to termination electrode.
Terminal can be made from suitable electrically non-conductive material (comprising resin).Especially, terminal can be synthetic resin, for example epoxy resin.
Instead, terminal can be the solid-state components that adhesively are fixed to the far-end of elongated member, with the intended shape of hermetic terminal and formation termination electrode.
The shape of this expectation can be a dome shape roughly.
Conductive material can be any of multiple material.Preferably, conductive material divides two stages to apply.At first, the ground floor of conductive material can apply with liquid form.This liquid form can be liquid carrier, particularly volatile vehicle, solvent for example, and this liquid carrier comprises conductive compositions solvation or synthetic or comprises solid-state conductive compositions.The subclass of these materials can be to comprise for example China ink of silver of particulate conducting metal, alloy or mechanism.
As noted above, ground floor can be applied to non-conductive terminal and be applied to conduction region, comes bridge joint conduction region and terminal.This conductive layer can apply by suitable method, comprises brushing, dipping, bat printing or the like.
This layer can further utilize conductive biological compatible material (for example suitable metal) to cover thereon, and suitable metal is platinum for example.
According to a forth aspect of the invention, provide a kind of electric lead, it comprises:
Elongated member, it has near-end and far-end, at least one electric conductor, this electric conductor is contained in this elongated member, and from the near-end of elongated member towards remote extension, stop in the conduction region of this at least one electric conductor outside being arranged in elongated member;
Non-conductive terminal, it is arranged away from conduction region and at the far-end of elongated member; And
At least layer of conductive material, its bridge joint conduction region and non-conductive terminal are to form the termination electrode of this conductive component.
According to a fifth aspect of the invention, provide a kind of method of making electric lead, this method comprises:
Elongated member is provided, and it has near-end and far-end, at least one electric conductor, this electric conductor is contained in this elongated member, and from the near-end of this elongated member towards remote extension, this at least one electric conductor with the middle termination of being electrically connected of conduction region, this conduction region is arranged in outside the elongated member;
In elongated member, form access point, so that the access for this at least one electric conductor to be provided;
Do not apply radiation opaque (radio opaque) material to vertically aiming at still with the zone of the electric elongated member that contacts of this access point with this access point; And
Layer of conductive material forms conduction region by applying at least around elongated member, makes it to contact by access point and conductor are electric, and covers on this radiation opaque material.
According to a sixth aspect of the invention, provide a kind of electric lead, it comprises:
Elongated member, it has near-end and far-end, at least one electric conductor, this electric conductor is contained in the elongated member, and from the near-end of this elongated member to remote extension;
Access point, it is formed on the pre-position in the wall of elongated member, so that the access for electric conductor to be provided;
Radiation opaque material district, it is had by elongated member the zone of the elongated member that vertically aligns with access point but separate from this access point circumference; And
At least layer of conductive material, this layer has in the pre-position of elongated member, contacts to provide by access point with the electric of electric conductor, and covers on the described radiation opaque material.
Access point can be the form of the slit of lateral arrangement in the wall of elongated member.In this respect, this elongated member can be spiral type be wound with the form of the tubular part of a plurality of electric conductors, these a plurality of electric conductors are embedded in the wall of this elongated member.Therefore, slit can be along the winding direction of this electric conductor.
Among the embodiment in this aspect of the invention, the radiation opaque material can be one deck radiation opaque material, and it is applied to the outer surface of elongated member, to form cuff around elongated member.This cuff can be in the position relative with access point diameter on the elongated member.This radiation opaque material can apply by bat printing.
Afterwards, this method can comprise and applies conductive material layer.This conductive material layer can comprise ground floor, example silver China ink as mentioned previously.Afterwards, ground floor can utilize the second bio-compatible conductive material (for example platinum) to cover thereon.
Among another embodiment in this aspect of the invention, the radiation opaque material can be inserted in the groove that forms in elongated member.This groove can form in the zone of the elongated member relative with the access point diameter.This groove can have any suitable shape, for example slit, cross shape, circle or the like.In this embodiment, this conductive layer can divide two stages to apply again.These layers can apply by bat printing.
This radiation opaque material can comprise about electrically non-conductive material of 70% to 80% and about jointing material of 20% to 30%.
This jointing material can comprise epoxy resin.Preferably, the epoxy resin of radiation opaque material mates with convenient bat printing with the epoxy resin of silver China ink.
Under the radiation opaque material was contained in situation in the groove of elongated member, it is the same with the epoxy resin that is used for populating access point that the epoxy resin of this radiation opaque material can be selected as.This purpose for bio-compatibility is favourable.
Description of drawings
Fig. 1 has schematically shown the part cutaway side sectional view of electric lead according to an embodiment of the invention;
Fig. 2 a has schematically shown the step of the method for the electric lead that is used for shop drawings 1 according to an embodiment of the invention to 2f;
Fig. 3 has schematically shown the electric lead after finishing this method;
Fig. 4 has shown the schematic cross sectional end view of the electric lead that method is according to another embodiment of the present invention made;
Fig. 5 has shown the schematic side elevation of the part of the electric lead that method is according to still another embodiment of the invention made;
Fig. 6 a to 6d schematically shown according to another embodiment of the present invention with the first electric contact of electric lead step from the method for the second electric contact electric insulation of electric lead;
Fig. 7 a has schematically shown according to still another embodiment of the invention the step of method that is used to make electric lead to 7e;
Fig. 8 has schematically shown the 3-D view of initial step of method that is used to make electric lead according to still a further embodiment;
Fig. 9 has shown the schematic cross sectional end view of first example of the electric lead of making according to a method again of making electric lead;
Figure 10 has shown the schematic cross sectional end view of second example of the electric lead of making according to a method again of making electric lead; And
Figure 11 a has schematically shown the modification of the example of the electric lead that shows among Fig. 9 to 11d.
The specific embodiment
With reference to the accompanying drawings, according to one embodiment of present invention, the electric lead according to the method that is used to make electric lead is made utilizes reference number 10 to represent usually.
Fig. 3 has shown the effect of the electrode sleeve that plays conduit and the side view of the resulting electric lead 10 that extends from introducer 30 or similar device.This lead 10 comprises a plurality of electrodes that vertically separate 11, and at least some of these electrodes 11 are band electrodes.
As what describe in paragraph before, electric lead 10 is used as the electrode sleeve of cardiac catheter.This electrode 11 is as induction electrode, responds to electrical activity in the muscle of heart whether (normally).In addition, electrode 11 can be used for melting the zone of the tissue of heart, corrects that some are unusual.
Therefore, each electrode 11 just begins operation as induction electrode.Such electrode 11 makes the clinician can be identified in the zone of the electrical Interference in patient's the heart.This electrical Interference may be caused by the infringement zone of the heart tissue of " misfire (mis-firing) ".In case the location, this identical electrode 11 can be switched to ablation functionality to melt this damaging tissue.
The manufacturing of electric lead 10 is presented at Fig. 2 a in 2f.Originally, as showing, provide internal part 12 in Fig. 2 a, it is by for example polyethylene or polyether block amide (PEBAX) manufacturing of suitable polymers.Other polymeric materials also are acceptables and can easily determine from this area.
As shown in Fig. 2 b, a plurality of conductors 13 are reeled around the outer surface of internal part 12 in a spiral manner.Alternate, conductor 13 is contained in the inner chamber of internal part 12.Up to 24 or more conductor 13 can be used in the electric lead 10, and spiral type ground twines the inner chamber of internal part 12 or is arranged in the inner chamber of this internal part.
As shown in Fig. 2 c, for example by outstanding formation outer polymer jacket 14 on internal part 12 and conductor 13, to form elongated member 10a.This outer polymer jacket 14 is from being similar to or the material manufacture the same with the material of internal part 12.But other materials can be selected the content as design alternative.
The elongated member 10a that comprises internal part 12, conductor 13 and outer polymer jacket 14 by heat treatment so that this outer polymer jacket 14 is fixed to internal part 12 and conductor 13.Should be realized that the internal layer that the wall of electric lead 10 therefore can be limited by internal part 12 effectively, the intermediate layer that is made of spiral type wound conductor 13 and the skin that is limited by external jacket 14 constitute.In fact, conductor 13 is embedded in the wall, and has seldom the polymeric material of (if any) between the adjacent turn of conductor 13, so has limited mobile performance between the adjacent turn, thereby has increased the flexibility of electric lead 10.
As shown in Fig. 2 d,, reach or expose the desired length of one or more leads 13 by the part of this external jacket 14 of cut.Cut is accurate, and provides the part 32 of removing outer polymer jacket 14 easily to produce the appropriate method of opening 34 simultaneously.Be removed the zone 34 of outer polymer jacket, had the width of width of the conductor 13 of the exposure of being similar to, and had the selection length that the predetermined length along conductor 13 of the coiling of following conductor 13 or spirality path extends.The amount of the outer polymer jacket of removing 14 depends on the demand of final electrode 11 largely.For example, have such example, wherein expectation exposes two or more adjacent conductors 13, with the electrode 11 of mechanical strength that electrical conductivity with increase and increase are provided.
If conductor 13 is insulated, expose the counterpart of the step of conductor except cutting and removal outer polymer jacket 14, also cut and remove the insulating barrier on lead.
As shown in Fig. 2 e, the opening 34 that is formed in the outer polymer jacket 14 utilizes the above for example silver-colored filling epoxy resin of electroconductive binder 15 that type is discussed to fill fully.This conductor 13 that is coated with electroconductive binder 15 provides competent electrical conductivity to play the effect of electrode 11.Such electrode 11 has special applications as induction electrode.
Yet as shown in Fig. 2 f, this method preferably further comprises the step of utilizing the solvent that contains one or more conductive materials to cover this electroconductive binder 15.The kind of suitable material is discussed in the above.These materials can apply in many ways, and for example splash, static be long-pending attached, as by brushing or the direct application of padding or the like.Use the bat printing that utilizes silver to fill China ink or palladium filling China ink or palladium/silver China ink 16 to obtain result preferably.
Be coated with platinum layer 17 above the bat printing coating of electroconductive binder 15 or China ink 16, to increase electrical conductivity across electrode.The electrode 11 that comprises platinum layer 17 melts except induction also is applicable to.Palladium 17 is applied to electrode 11 by chemical plating, but also can apply by the electrodeposition technology.
In Fig. 4 of accompanying drawing, another embodiment of the present invention has been described, wherein with reference to accompanying drawing before, same reference numbers is represented same section, unless otherwise noted.In this embodiment, a plurality of parts 32 (but be not presented among Fig. 4 be presented among Fig. 2 d) are excised at the interval that separates by the circumference around the sheath externally 14, to form a plurality of openings 34 that separate along circumference, insert a plurality of electric conductors 13.Though the opening 34 that Fig. 4 describes is vertically alignment, should know that opening 34 can be relative to each other staggered along the length of external jacket 14.
Each opening 34 is full of electroconductive binder 15, and bat printing around the circumference of the external jacket 14 on the electroconductive binder 15 of conductive material layer 16 in covering each opening 34.Biocompatible metal layer 17 is applied on the conductive material layer 16.
In case applied metal level 17, carry out cut 19 by layer 16 and 17, to form a plurality of discrete electrodes 11 that separate along circumference.An advantage knowing this embodiment of the present invention is, can realize three-dimensional induction or melts.In addition, more the easy arrangement conduit 10, because the electrode 11 of conduit 10 is not critical with respect to the position at the position of the patient body that will treat, because always may have and at least one electrode 11 that tissue contacts.
With reference now to accompanying drawing, Fig. 5 has described another embodiment of the present invention.Again, with reference to accompanying drawing before, same reference numbers is represented same section, unless otherwise noted.
In this embodiment, replace by the layer 17 of each electrode 11 of bat printing, ring 60 is applied on the layer 16.This ring 60 is crossed layer 16 appropriate position that is fixed on this external jacket 14 that are associated with external jacket 14 by suitable technique for fixing, this technique for fixing for example binding agent, curl, interference fit or the like.
Measurement is useful in the temperature at electrode 11 places, and electrode 11 is used to melt under the situation of purpose especially therein.Therefore, this electric lead 10 comprises thermocouple 20 (Fig. 6 b) or other suitable temperature measurement units.
As shown in Fig. 6 a, in the variation that comprises thermocouple 20, this thermocouple 20 comprises by first line 21 of copper production and second line 22 made by constantan.This outer polymer jacket 14 is for example cut by cut, to expose line 21 and 22.Electroconductive binder 15 is applied to the line of exposure, as shown in Fig. 6 b.This lead binding agent 15 makes two lines 21 and 22 electric each other contacts of thermocouple 20, thereby thermocouple junction 23 is provided.
When forming thermocouple 20 by this way and when guaranteeing the precise dose reading, this thermocouple 20 needs as the electrode 11 from being associated described in the following steps insulate.As shown in Fig. 6 c, be exposed and after electroconductive binder 15 has been applied to the line 21 and 22 of exposure at the line 21 and 22 of thermocouple 20, line and binding agent are exposed to salt (NaCl) solution and electric current flow through thermocouple 20 from constant voltage source 26 line 21 and 22.The electric current that flows through binding agent 15 that obtains causes the metal in this binding agent to be converted into metal chloride.When this binding agent 15 was silver-colored filling epoxy resin, the silver on the outer lining face (facing surface) of this binding agent was converted into relatively thin silver chloride layer 25, and as insulating barrier, with electrode 11 electric insulations of thermocouple 20 from electric lead 10.
As shown in Fig. 6 d, the binding agent 15 of electrode 11 and the binding agent 15 of thermocouple 20 utilize silver to fill black 16 bat printings then, and platinum layer 17 selectively is applied to China ink 16.
Example
Cable source from the Microhelix of Oregon Portland (Microhelix, Portland, Oregon).This cable prepares by mold pressing PEBAX sheath on polymer-coated line axle.The mixture of the copper of nylon/polyurethane insulating and constantan line (each 0.125mm) by with control gradient/winding angle spiral type be wound on around the line axle of polymer-coated.This PEBAX sheath is arranged on the winding line then.Cable section of being cut into that obtains and removal axle.This cable is fixed to winding line by heat treatment with outside PEBAX sheath then.
On each line of pre-position, cut excimers (excimer) cut window then.The exact position of window is programmed in the laser.Outside PEBAX sheath on each line is removed together with the insulating barrier of this line, and the electric wire under not disturbing.
The opening that removal by PEBAX and insulating regions forms uses pneumatic distributor to fill with the silver-colored filling epoxy resin from Creative Materials.This silver filling epoxy resin solidifies under about 140 ° temperature, carries out Cement Composite Treated by Plasma subsequently and reach about 1 minute in the argon atmosphere.
This silver filling epoxy resin zone utilizes silver filling China ink to come bat printing then.The plate that has about the breach of expectation size of electrode and spacing utilizes silver to fill black wiping, leaves over China ink in breach.Liner is lowered on the top of this plate along the length of China ink filling well then.This liner picks up China ink and is arranged on the cable, and is like this should the China ink liner corresponding with the epoxy regions on the cable, China ink is deposited on the cable on this epoxy regions.This step is along with the rotation of cable is repeated repeatedly, and a series of like this bands are formed on around the circumference of cable.
Cable solidifies in about 140 ℃ stove then and reaches 15 hours.
The band of cable further utilizes acid PdCl solution catalyzing then.
Finally, cable use hydrazine is placed under about 60 ℃ in the electroless plating Pt solution that can buy as Reducing agent and reaches about 1 hour.Thickness is approximately 0.5 micron palladium layer and forms on tape, to form final band electrode.
Fig. 7 a has with reference to the accompanying drawings described another embodiment that makes the method for electric lead 10 to 7e.With reference to accompanying drawing before, identical reference number is represented same section, unless otherwise noted.
In this embodiment of the present invention, electrode 11 forms at the interval that separates along the length of elongated member 10a, with its under conductor 13 (not shown in the 7e) electrical communication at Fig. 7 a.
In following step, as shown in Fig. 7 of accompanying drawing d, configured ends 46 is coated with conductive silver ink, the composition of this conductive silver ink with form electrode 11 in use identical.Therefore will know that termination electrode 46 was forming before applying platinum layer on the electrode 11.
Therefore, in case configured ends 46 has been coated with Yin Mo, all of electrode 11 and termination electrode 48 all are coated with platinum layer 17, as shown in Fig. 7 of accompanying drawing e.Again, platinum layer 17 applies by chemical plating.
With reference now to Fig. 8 of accompanying drawing, to Figure 11, the another method of making electric lead 10 has been described.Again, with reference to accompanying drawing before, identical reference number is represented identical part, unless otherwise indicated.
In this embodiment, externally form before the electrode 11 around the sheath 14, in case externally formed each opening 34 in the sheath 14, each of then radiating at least some of opaque material 50 and opening 34 applies with vertically being aligned with each other.
Under the situation of the embodiment that in Fig. 8 of accompanying drawing and Fig. 9, shows, radiation opaque material 50 with the form of cuff (cuff) 52 externally the circumference of sheath 14 part around apply.
Radiation opaque material 50 applies by bat printing, and comprises electrically non-conductive material between 70% to 80% and 20% to 30% binding agent.This radiation opaque material is the Tyngsboro that is derived from the U.S., MA, the radiation opaque ink of the Creative Material company on 01879 141 Middlesex roads.The stick portion tradition of this radiation opaque material is an epoxy resin.The epoxy resin coupling of the epoxy resin of this radiation opaque material 50 and silver layer 16 is favourable for bio-compatibility like this.
In case applied radiation opaque material 50, conductive silver material layer 16 by bat printing to cover radiation opaque material and above the binding agent in opening 34 15.Afterwards, apply platinum layer 17 by chemical plating.
Among the embodiment that in Figure 10 of accompanying drawing and Figure 11, shows, replace applying radiation opaque material 50 as cuff 52, with 34 one-tenths diameter relativenesses ground of opening formation groove 54 in the sheath 14 externally.Know that the degree of depth of this groove 54 is to make it not be exposed to any conductor 13 in the outer cover 14.
Radiation opaque material 50 is filled in the groove 54.In this embodiment, the epoxy resin of radiation opaque material is selected as identical with the conductive fill 15 employed epoxy resin that are used to form opening 34.Again, this purpose for bio-compatibility is favourable.
In case groove 54 comprises radiation opaque material 50, silver China ink 16 applies by bat printing, and then is that counter electrode 11 carries out chemical plating and forms platinum layer 17.
Should be understood that silver ink layer 16 or platinum layer 17 need not extend, and depend upon circumstances on radiation opaque material 52 or 54.Essential just radiate opaque material 52 or 54 with its explicitly electrode 11 vertically aim at.
The advantage of this embodiment is: the radiation zone of opacity forms with electrode 11 aims at, and allows to carry out arranging fast and accurately of electrode 11 by the clinician who observes the position of electrode 11 on fluorescent screen.
One skilled in the art will appreciate that for the method for this description and can make many changes and/or modification, and do not depart from broadly described spirit or scope.Therefore special the description all be considered to descriptive and nonrestrictive in all fields.
These modifications and change all are included in the scope of the present invention that is defined by the following claims.
Claims (46)
1. method that is used to make electric lead with one or more electrodes, this method comprises:
Elongated member is provided, and it has at least one polymer areas and further has at least one electric conductor, and this electric conductor extends to small part along a length of this elongated member, and is contained in the wall of this elongated member;
Insert a length of this at least one electric conductor at least one polymer areas place; And
Length at least one electric conductor of this access applies electroconductive binder.
2. method according to claim 1, wherein said electroconductive binder comprises silver-colored filling epoxy resin.
3. method according to claim 2, at least some of the silver particles of wherein said silver-colored filling epoxy resin are coated with platinum or palladium.
4. according to any one described method of claim before, it comprises described electroconductive binder is applied at least a conductive material.
5. method according to claim 1, it comprises that utilization comprises that the metal of platinum covers above the described electroconductive binder.
6. method according to claim 4, it comprises that utilization comprises that the metal of platinum covers on the described conductive material.
7. according to any described method of claim 1 to 3, wherein said elongated member comprises a plurality of electric conductors, and wherein this method comprises a length that inserts in a plurality of electric conductors each, the interval that the circumference of these a plurality of electric conductors around described elongated member separates, this method comprises that also the length to the access of each electric conductor applies the liner of electroconductive binder.
8. method according to claim 7, it comprises that each liner to electroconductive binder applies the layer of at least a conductive material.
9. according to claim 7 or 8 described methods, it comprise utilize comprise that platinum or palladic metal level cover electroconductive binder each above the liner.
10. method according to claim 9, the liner of wherein said electroconductive binder is arranged in around the circumference of described elongated member with vertical aligned relation, and wherein this method applies metal level as pantostrat around being included in the circumference of described elongated member, and thereafter, this layer is separated into a plurality of electric insulation sections that are arranged in the interval that circumference separates, with a plurality of discrete electrodes of the circumference arranged around that is formed on described elongated member.
11. according to claim 6 or the described method of claim 10, it comprises by installing ring on described elongated member and this ring is fixed on the appropriate location and applies the metal that comprises platinum.
12. according to the arbitrary described method of claim before, it comprises by following steps from the electric contact insulation of described one or more electrodes with described electric lead:
Insert described electric contact;
The first electric contact is applied electroconductive binder; And
The described electroconductive binder of electrochemical treatments makes the part of described electroconductive binder be converted into non-conducting portion.
13. method according to claim 12, wherein the described conductive material of electric treatment comprises and makes electric current pass through described electric contact in ionic environment.
14. method according to claim 13, wherein said ionic environment comprise salt (NaCl) solution, with will the electrochemical metal in the described electroconductive binder be converted to metal chloride.
15. according to any described method of claim 12 to 14, wherein said electric contact is the contact of thermal cross.
16. one kind with the first electric contact of the electric lead method from the second electric contact electric insulation of described electric lead, this method comprises:
Insert the first electric contact;
The described first electric contact is applied electroconductive binder; And
The described electroconductive binder of electrochemical treatments makes the part of described electroconductive binder be converted into non-conducting portion.
17. method according to claim 16, wherein said electrochemical treatments comprise the step that makes electric current pass through the electric contact in ionic environment.
18. method according to claim 17, wherein said ionic environment comprise salt (NaCl) solution, with the electrochemical metal in the described electroconductive binder be converted to metal chloride.
19. according to any described method of claim 15 to 18, the wherein said first electric contact comprises the temperature sense parts.
20. according to any described method of claim 16 to 19, the wherein said second electric contact comprises the power transfer electrode.
21. method according to claim 20, wherein said temperature sense parts comprise thermocouple, and this thermocouple has first line that is made of copper and second line of being made by constantan.
22. a method of making electric lead, this method comprises:
Elongated member is provided, this elongated member has near-end and far-end, be contained in the described elongated member and from the near-end of described elongated member at least one electric conductor to its remote extension, this at least one electric conductor with the middle termination of being electrically connected of conduction region, this conduction region is arranged in outside the described elongated member;
Cut-out is away from the elongated member of described conduction region;
Formation is away from the non-conductive terminal of described conduction region; And
On described conduction region and terminal, apply conductive material, to form the termination electrode of described electric lead.
23. a method of making electric lead, this method comprises:
Elongated member is provided, it has near-end and far-end, this elongated member has one or more polymer areas, and further have a plurality of electric conductors, described electric conductor is along the remote extension to small part towards described elongated member of a length of described elongated member, and described electric conductor is accommodated in the wall of described elongated member;
For at least some of described electric conductor each, form the electric conduction region that contacts with its electric conductor that is associated by following steps:
By the polymer areas of described elongated member, insert each a length of at least some electric conductors, and the electric conductor of each access is applied electroconductive binder;
Apply conductive material at the access point place that is associated with each electric conductor, to form a plurality of conduction regions that vertically separate along the length of described elongated member;
Cut-out is away from the elongated member of one of described conduction region;
Apply non-conductive terminal away from this conduction region; And
Apply conductive material and come described conduction region of bridge joint and terminal, to form the termination electrode of described elongated member.
24. according to claim 22 or the described method of claim 23, it is included under the liquid state and applies terminal.
25. method according to claim 24, it comprises that two stages of branch apply terminal, and ground floor is applied in sealing the far-end of described elongated member, and the second layer is applied in and is shaped to provide intended shape to termination electrode.
26. according to claim 22 or the described method of claim 23, it comprises that the far-end to described elongated member applies solid-state terminal.
27. according to claim 22 or the described method of claim 23, it comprises that two stages of branch apply conductive material.
28. method according to claim 27, it comprises described non-conductive terminal and described conduction region is applied ground floor, with described conduction region of bridge joint and described terminal.
29. method according to claim 28, it comprises and utilizes the conductive biological compatible material to cover on the described ground floor.
30. an electric lead, it comprises:
Elongated member, it has near-end and far-end, be contained in the described elongated member and at least one electric conductor from the near-end of described elongated member towards remote extension, this at least one electric conductor with the middle termination of being electrically connected of conduction region, this conduction region is arranged in outside the described elongated member;
Non-conductive terminal, it is arranged away from described conduction region and at the far-end of described elongated member; And
At least layer of conductive material, described conduction region of its bridge joint and non-conductive terminal are to form the termination electrode of conductive component.
31. lead according to claim 30, wherein said terminal is by the electrically non-conductive material manufacturing that comprises resin.
32. lead according to claim 31, wherein said terminal are synthetic resin.
33. according to any described lead of claim 30 to 32, wherein said terminal is solid-state components, it adhesively is fixed to the far-end of described elongated member, to seal the intended shape of described end and the described termination electrode of formation.
34. a method of making electric lead, this method comprises:
Elongated member is provided, it has near-end and far-end, be contained in the described elongated member and at least one electric conductor from the near-end of described elongated member towards remote extension, this at least one electric conductor with the middle termination of being electrically connected of conduction region, described conduction region is arranged in outside the described elongated member;
In described elongated member, form access point, so that the access for described at least one electric conductor to be provided;
To the zone of described elongated member, with described access point vertically aim at ground but not with the electric radiation opaque material that applies contiguously of described access point; And
Layer of conductive material forms conduction region by applying at least around described elongated member, makes it to contact with described conductor is electric by described access point, and covers on the described radiation opaque material.
35. method according to claim 34, it comprises that the outer surface to described elongated member applies described radiation opaque material as layer, to form cuff around described elongated member.
36. method according to claim 35, it comprise with described cuff be arranged in described elongated member on the relative position of described access point diameter.
37. method according to claim 36, it is included in and applies described conductive material layer on the described cuff, and this conductive material layer comprises first conductive layer that is coated with the second bio-compatible conductive material layer on it.
38. method according to claim 34, it comprises described radiation opaque material is inserted in the groove that is formed in the described elongated member that this groove is formed in the zone of the described elongated member relative with described access point diameter.
39. an electric lead, it comprises:
Elongated member, it has near-end and far-end, is contained in the described elongated member and at least one electric conductor from the near-end of described elongated member towards remote extension;
Access point, it is formed on the pre-position in the wall of described elongated member, so that the access for described electric conductor to be provided;
Radiation opaque material district, it has by being in the described elongated member of vertically aiming at still the zone of the described elongated member that separates from described access point circumference with described access point; And
At least one conductive material layer, its pre-position at described elongated member has, and contacts with the electric of described electric conductor to provide by described access point, and covers on the described radiation opaque material.
40. according to the described lead of claim 39, wherein said access point is the form of the slit of the lateral arrangement in the wall of described elongated member, this slit is along the winding direction of described electric conductor.
41. according to claim 39 or the described lead of claim 40, wherein said radiation opaque material comprises about electrically non-conductive material of 70% to 80% and about adhesive material of 20% to 30%.
42. according to the described lead of claim 41, wherein said adhesive material comprises epoxy resin.
43. according to claim 41 or 42 described leads, wherein said radiation opaque material applies as layer around the part of the circumference of described elongated member.
44. according to the described lead of claim 43, the epoxy resin of the adhesive material of wherein said radiation opaque material and the epoxy resin of described conductive material layer coupling.
45. according to the described lead of claim 42, wherein said radiation opaque material is contained in the groove of described elongated member, this groove arrangement is in respect to the relative position of the diameter of described access point.
46. according to the described lead of claim 45, it is identical with the epoxy resin that uses in filling described access point that the epoxy resin of wherein said radiation opaque material is selected as.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59965104P | 2004-08-05 | 2004-08-05 | |
| US60/599,651 | 2004-08-05 | ||
| US60/648,232 | 2005-01-28 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010101179839A Division CN101879347A (en) | 2004-08-05 | 2005-06-10 | Be used to make the method for electric lead |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101001663A true CN101001663A (en) | 2007-07-18 |
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ID=38693304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200580026483 Pending CN101001663A (en) | 2004-08-05 | 2005-06-10 | A process of manufacturing an electrical lead |
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| Country | Link |
|---|---|
| CN (1) | CN101001663A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102551672A (en) * | 2010-12-29 | 2012-07-11 | 韦伯斯特生物官能(以色列)有限公司 | Braid with integrated signal conductors |
| CN104870051A (en) * | 2012-10-31 | 2015-08-26 | 美敦力公司 | Implantable medical electrical lead conductors and construction methods |
-
2005
- 2005-06-10 CN CN 200580026483 patent/CN101001663A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102551672A (en) * | 2010-12-29 | 2012-07-11 | 韦伯斯特生物官能(以色列)有限公司 | Braid with integrated signal conductors |
| CN102551672B (en) * | 2010-12-29 | 2016-08-10 | 韦伯斯特生物官能(以色列)有限公司 | There is the fabric of integration signal conductor |
| CN104870051A (en) * | 2012-10-31 | 2015-08-26 | 美敦力公司 | Implantable medical electrical lead conductors and construction methods |
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