CN100536861C - Preparation technology of metaplexis and rostellularia extract - Google Patents
Preparation technology of metaplexis and rostellularia extract Download PDFInfo
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- CN100536861C CN100536861C CNB2005101116415A CN200510111641A CN100536861C CN 100536861 C CN100536861 C CN 100536861C CN B2005101116415 A CNB2005101116415 A CN B2005101116415A CN 200510111641 A CN200510111641 A CN 200510111641A CN 100536861 C CN100536861 C CN 100536861C
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- herba
- extract
- ethanol
- dry extract
- seu radix
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Abstract
A process for preparing the extract of Japanese metaplexis herb and creeping rostellularia herb includes such steps as extracting in water or alcohol to obtain dryextract, diluting by water, separating by macroreticular adsorptive resin, and eluting. Said extract can be used to prepare medicine for treating infantile malnutrition with accumulation.
Description
Technical field:
The present invention relates to the preparation technology of a kind of Herba seu radix metaplexis, Herba Rostellulariae extract.
Background technology:
Contain the prescription of Herba seu radix metaplexis, Herba Rostellulariae composition, the Chinese traditional patent formulation preparation valiant fighter syrup that is used for the infantile malnutrition treatment is put into 17 of ministry standards, is the kind by the exclusive development and production of Tianshikang Chinese Medicines Co., Ltd., Jiangxi.The Main Ingredients and Appearance of this medicine is the extract of Herba seu radix metaplexis and Herba Rostellulariae, because there is defective in the preparation technology of this extract, causes the effective percentage of this medicine on the low side, has only 90%.
Summary of the invention:
The preparation technology who the purpose of this invention is to provide a kind of Herba seu radix metaplexis, Herba Rostellulariae extract is used to make the Chinese medicine for the treatment of infantile malnutrition with the produced Herba seu radix metaplexis of this technology, Herba Rostellulariae extract, can improve the effective percentage of this Chinese medicine.
Purpose of the present invention can realize by the following method:
(1) gets Herba seu radix metaplexis, the Herba Rostellulariae medical material of equivalent recipe quantity, decoct with water secondary, 1.5-2 hour for the first time, 1-2 hour for the second time, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.08-1.25 (60 ℃), adds ethanol, makes the alcohol amount of containing reach 50-85%, left standstill 24 hours, filter, filtrate recycling ethanol continues concentrating under reduced pressure, cold drying gets dry extract; Or get Herba seu radix metaplexis, the Herba Rostellulariae medical material of equivalent recipe quantity, chopping is extracted secondary with ethanol or the methanol eddy of 40%-95%, each 1-3 hour, merge extractive liquid, filtered, and reclaimed alcohol to there not being the alcohol flavor, continued concentrating under reduced pressure, cold drying, dry extract.Or reclaim ethanol and extremely do not have the alcohol flavor, concentrate, add water washing and precipitating, to leave standstill, the precipitum cold drying gets dry extract.
(2) with above-mentioned Herba seu radix metaplexis, Herba Rostellulariae dry extract, thin up pumps into macroporous adsorptive resins with constant flow pump and adsorbs, and doubly measures the washing of column volume with 1-3, closely colourless to eluent, last 50% and 95% ethanol difference eluting secondary with 2-6 times of medical material amount, and collect eluent respectively, reclaim ethanol, merge extractive liquid,, concentrating under reduced pressure continues cold drying, gets dry extract.
Described macroporous adsorbent resin model can be one or more applied in any combination among D101,24-6, LD605, LD606, LD607, D4006, AB-8, HPD100, HPD300, HPD400, HPD500, the HPD600.
Technology of the present invention is simple, the Herba seu radix metaplexis of producing, Herba Rostellulariae extract purity height.
Claims (1)
1, the preparation technology of a kind of Herba seu radix metaplexis and Herba Rostellulariae extract, its technology is as follows:
(1) gets the Herba seu radix metaplexis and the Herba Rostellulariae medical material of equivalent recipe quantity, decoct with water secondary, 1.5-2 hours for the first time, 1-2 hours for the second time, collecting decoction filtered, it is 1.08-1.25 clear paste that filtrate is concentrated into relative density, adds ethanol, makes to contain the alcohol amount and reach 50-85%, left standstill 24 hours, filter, filtrate recycling ethanol continues concentrating under reduced pressure, cold drying gets dry extract; Or get the Herba seu Radix Metaplexis hemsleyanae and the Herba Rostellulariae medical material of equivalent recipe quantity, and chopping, ethanol with 40%-95% or methanol eddy extract secondary, and each 1-3 hour, merge extractive liquid, filtered; Reclaim the pure alcohol flavor continuation concentrating under reduced pressure that extremely do not have, cold drying gets dry extract; Or reclaim ethanol and extremely do not have the alcohol flavor, concentrate, add water washing and precipitating, to leave standstill, the precipitum cold drying gets dry extract;
(2) with above-mentioned Herba seu radix metaplexis and Herba Rostellulariae dry extract, thin up, the macroporous adsorptive resins that pumps into low pole or nonpolar or its combination with constant flow pump adsorbs, with the washing of 1-3 times of amount column volumes, closely colourless to eluent, distinguish the eluting secondary with 50% and 95% ethanol of 2-6 times of medical material amounts at last, and collect eluent respectively, reclaim ethanol, merge extractive liquid,, concentrating under reduced pressure continues cold drying, gets dry extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005101116415A CN100536861C (en) | 2005-12-14 | 2005-12-14 | Preparation technology of metaplexis and rostellularia extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005101116415A CN100536861C (en) | 2005-12-14 | 2005-12-14 | Preparation technology of metaplexis and rostellularia extract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1823861A CN1823861A (en) | 2006-08-30 |
| CN100536861C true CN100536861C (en) | 2009-09-09 |
Family
ID=36934801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005101116415A Expired - Fee Related CN100536861C (en) | 2005-12-14 | 2005-12-14 | Preparation technology of metaplexis and rostellularia extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100536861C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102934741A (en) * | 2012-11-30 | 2013-02-20 | 辽宁医学院 | Chinese herbal medicine feed additive containing Metaplexis japonica Makino |
| CN104706698B (en) * | 2015-04-08 | 2017-11-21 | 青岛大学 | Trailing plants Japonica C21 steroidal extracts and its production and use |
| CN108096302A (en) * | 2018-01-10 | 2018-06-01 | 湖北中医药大学 | A kind of Herba Rostellulariae extract of platelet aggregation-against and its preparation method and application |
-
2005
- 2005-12-14 CN CNB2005101116415A patent/CN100536861C/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| 药品标准 中药成方制剂 第十七册. 中华人民共和国卫生部药典委员会，206. 1998 |
| 药品标准 中药成方制剂 第十七册. 中华人民共和国卫生部药典委员会，206. 1998 * |
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| Publication number | Publication date |
|---|---|
| CN1823861A (en) | 2006-08-30 |
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