CN100531744C - Method for extracting active components of ginseng by mechanical means - Google Patents

Method for extracting active components of ginseng by mechanical means Download PDF

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Publication number
CN100531744C
CN100531744C CNB2005800113865A CN200580011386A CN100531744C CN 100531744 C CN100531744 C CN 100531744C CN B2005800113865 A CNB2005800113865 A CN B2005800113865A CN 200580011386 A CN200580011386 A CN 200580011386A CN 100531744 C CN100531744 C CN 100531744C
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radix ginseng
powder
ginseng
mill
active component
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CN1942109A (en
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金尚郁
朴东俊
金永灿
金敬卓
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Kuan Industrial Co Ltd
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    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05BELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00Heating by electric, magnetic or electromagnetic fields
    • H05B6/64Heating using microwaves
    • H05B6/6408Supports or covers specially adapted for use in microwave heating apparatus
    • H05B6/6411Supports or covers specially adapted for use in microwave heating apparatus the supports being rotated
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/01Instant products; Powders; Flakes; Granules

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Abstract

The present invention relates to a method of processing ginseng and extracting active components therefrom; more specifically, a method of extracting active components of ginseng by mechanical means of milling and air-classifying dehydrated ginseng via a mill and an air classification system, respectively. The constitution of the present invention includes: a process of placing the dehydrated ginseng into a crude mill and obtaining ginseng granules having 60~80mesh of fineness; a process of placing thus obtained granules into a single track jet mill to obtain hyperfine ginseng powder with its particles having a size of 1~100 mum; a process of air-classifying thus obtained powder in an air classification system to produce a powder with its particles having a size of 1~9 mum.

Description

Extract the method for the active component of Radix Ginseng by mechanical means
Technical field
The present invention relates to Radix Ginseng is processed to extract the method for active component from Radix Ginseng; More specifically, the present invention relates to use grinding machine to milling through the Radix Ginseng of dehydration and the Radix Ginseng through milling being carried out selecting crude drugs with winnower and from Radix Ginseng, extract the method for active component by mechanical means with aidr bells blast system.
Background technology
After Garrigues in 1854 isolated panaxcoside, the scientific research of relevant Radix Ginseng had obtained comprehensively carrying out.Particularly the main component saponin of panaxcoside has become the focus of research; Correspondingly, the various products that contain saponin have obtained positive exploitation and sale.
In addition, along with the growth of the sale of the various products that contain constituent of ginseng, the productivity's that improves the Radix Ginseng product interest is also being increased.That is to say that along with increasing of the various products that contain the Radix Ginseng active component that come into the market, providing at a low price, the Radix Ginseng product has become main market strategy.For this reason, the method for minimizing Radix Ginseng production cost has obtained deep research.
Yet although to improving the research that the method for extracting the efficient of active component from Radix Ginseng continues, research worker does not also propose any effective method.Extracting the method that active component adopted at present from Radix Ginseng is hydrothermal solution extraction method or organic solvent extraction method.
The shortcoming of hydrothermal solution extraction method and organic solvent extraction method is: complex manufacturing, and production cost can not significantly be reduced, and this is because the constituent of ginseng waste material contains the active component of utmost point low content.
In addition, study improving the method for from Radix Ginseng, extracting the efficient of active component by the extraction conditions in the control said method.Yet the effort of adopting these methods to improve extraction efficiency has reached their limit; Therefore, study shortening extraction time.
In case develop the active component required time is extracted in shortening from Radix Ginseng method, just can obviously reduce the Radix Ginseng production cost of products; Yet the result does not also have extremely successful.
Therefore, press for the active component required time is extracted in shortening from Radix Ginseng the method for developing.
Summary of the invention
Technical problem to be solved
The present inventor has made great efforts to solve existing problem in the prior art; As a result, they propose to use grinding machine and aidr bells blast system to obtain to contain the simple and rapid method of Radix Ginseng powder of the Radix Ginseng active component of high percentage ratio.
Formation of the present invention comprises: will put into kibbling mill and obtain the operation that fineness is 60~80 purpose ginseng granules through the Radix Ginseng of dehydration; The granule of gained is sent in the single track aeropulverizer (single trackjet mill) and obtained the operation that particle size is the hyperfine Radix Ginseng powder of 1 μ m~100 μ m; And the Radix Ginseng powder to gained carries out selecting crude drugs with winnower and produces the hyperfine Radix Ginseng powder that particle size is 1 μ m~9 μ m in aidr bells blast system.
To put into kibbling mill and can provide superfine Radix Ginseng powder to the operation that the granule that so obtains carries out selecting crude drugs with winnower through the Radix Ginseng of dehydration at aidr bells blast system, described superfine Radix Ginseng powder contains polysaccharide acid (polysaccharide acid), total sugar, crude protein of high concentration etc., also contains the main component saponin of Radix Ginseng simultaneously; Therefore, this will shorten the extraction required time of active component from Radix Ginseng.
Formation to the grinding machine (kibbling mill) of granulation Radix Ginseng has no particular limits, but preferably uses such as grinding machines such as needle mill, impact mill, roller mill, vibratory bowl or colloid mills.In addition, the ginseng granules of milling is also had no particular limits with the formation of the single track aeropulverizer that obtains hyperfine Radix Ginseng powder, but preferably use such as aeropulverizer or vibratory bowl grinding machine grinding machines such as (vibratory bowl mill).
These millings and selecting crude drugs with winnower operation can be used as series interlocking operation and are undertaken by automatization.
With different such as existing methods such as hydrothermal solution extraction method and organic solvent extraction methods, the present invention extracts active component from Radix Ginseng method allows to use kibbling mill, single track aeropulverizer and aidr bells blast system to come carrying out rapid extraction such as Radix Ginseng active component such as saponin, acidic polysaccharose (acid polysaccharide), total sugar, crude protein.
The specific embodiment
Extracting the method for Radix Ginseng active component can further explain by following embodiment by the mechanical means with above-mentioned formation.
Provide these embodiment to come the present invention is explained in more detail, and, according to main points of the present invention, it will be apparent to those of ordinary skill in the art that scope of the present invention is not limited to these embodiment.
Embodiment
Embodiment 1
At first; Radix Ginseng to life in 6 years dewaters; take by weighing 4.5kg and do not comprise the Radix Ginseng of its upper end; being granulated into fineness in needle mill is about 60~80 purpose granules; promoting pressure and 0.7MPa with 2.0 kilograms/hour charging rate at 0.7MPa then mills under the condition of pressure in single track aeropulverizer (Alpine, Germany) to described particle grinding once.Adopt granularity analyser (LMS-30, Seishin, Japan) that the particles of powder degree of the gained of milling by electricity is measured, intermediate value granularity (median granularity) is X 10=2.511 μ m, X 50=7.789 μ m and X 90=25.245 μ m.
Then, in aidr bells blast system (Alpine, Germany) with 6,500rpm (rev/min), 5,000rpm, 3,500rpm and 2, the separation wheel of 000rpm (classification wheel) speed is to 4, the hyperfine Radix Ginseng powder of 341.6g carries out selecting crude drugs with winnower.That is to say, it is 6 that described hyperfine Radix Ginseng powder is put into separation wheel speed, in the aidr bells blast system of 500rpm, and fine powder that will be by separation wheel (6,500F) with unsanctioned corase meal (6,500C) separate, with 5, the speed of 000rpm puts on described corase meal then, will be by the described fine powder of taking turns (5,000F) with unsanctioned corase meal (5,000C) separate, then with 3, the speed of 500rpm puts on described 5, the 000C powder, will by described fine powder of taking turns (3,500F) with unsanctioned corase meal (3,500C) separate, then with 2, it is described 3 that the speed of 000rpm puts on, and the 500C powder will be by the described fine powder of taking turns (2,000F) with unsanctioned corase meal (2,000C) separate (seeing: table 1).
[table 1]
The selecting crude drugs with winnower condition
Carry out the number of times of sorting 1 2 3 4
Processing capacity (kilogram/hour) 2.5 2.3 2.8 3.0
Separation velocity (rpm) 6,500 5,000 3,500 2,000
Pressure reduction (mmAq) 300 300 280 300
Air-supply equipment (Hz) 54.5 56.4 60.1 60.5
Running time (hour) 100 100 75 50
The analysis result of the granularity of the Radix Ginseng powder by the selecting crude drugs with winnower gained under the condition of last table 1 is as shown in table 2.
[table 2]
The granularity analysis of Radix Ginseng powder
Figure C200580011386D00061
As above shown in the table 2, these results show that particle size increases with the reduction of separation velocity.
Then, by the AOAC method basis of above-mentioned Radix Ginseng powder through sorting is carried out quantitatively.Measure moisture by 105 ℃ of air dryings; Measure crude protein content by semimicro-Kjeldahl method; Come cinder content is carried out quantitatively by 550 ℃ of incinerations; Carbohydrate content is for getting rid of back remaining surpluses such as moisture, crude protein, cinder.Use without the Radix Ginseng powder of sorting and organize (seeing: table 3) in contrast.
Basis content (unit: weight %) through the Radix Ginseng powder of sorting
Sample Moisture Cinder Carbohydrate Crude protein
Matched group 6.72 4.36 76.21 15.22
2,000C 6.43 4.20 76.77 14.49
3,500C 6.25 4.17 77.55 14.58
5,000C 6.39 4.27 77.66 14.42
6,500C 6.85 4.34 76.11 14.66
2,000F 6.13 4.42 77.88 14.19
3,500F 6.01 4.44 76.68 15.37
5,000F 5.38 4.81 73.65 18.27
6,500F 5.54 5.04 71.51 20.99
As shown in table 3, crude protein and cinder tend to 5, and 000F and 6,500F obtain separating; Particularly 6, the crude protein concentration of 500F is up to 1.38 times of matched group concentration, and this shows active component enrichment by selecting crude drugs with winnower of Radix Ginseng, and depends on separation velocity through the content of the active component of enrichment.
Through the polysaccharide of the Radix Ginseng powder of sorting and the content analysis of saponin
Use glucose total sugar content to be measured by the phenol sulfuric acid process as reference material.Use β-D-galacturonic acid acidic polysaccharose content to be measured by a hydroxy phenyl method (m-hydroxyphenyl method) as reference material.
According to the method for analyzing constituent of ginseng, the 1g sample dissolution in the 80 volume % methanol of 30ml, is extracted and vacuum drying, thereby obtained powder, then described powder dissolution is extracted in distilled water and with ether, thereby obtain aqueous layer.Then, the aqueous layer that so obtains with butanols extraction, thereby obtain classified butanols, vacuum drying and obtain powder, with this powder dissolution in 50ml methanol and obtain wherein 100 μ l.
In the gained sample, 8 volume % vanillin-alcoholic solution of 300 μ l are mixed with the sulphuric acid of the 72 volume % of 4ml, measure the absorbance at 545nm place then and carry out quantitatively after 10 minutes 60 ℃ of colour developings.Employing is without the Radix Ginseng powder of the sorting matched group (seeing Table 4) as this method.
[table 4]
Through the polysaccharide of the Radix Ginseng powder of sorting and the content (unit: mg/g) of saponin
Sample Acidic polysaccharose Saponin Total sugar
Matched group 18.98 27.33 275.22
2,000C 16.99 24.89 252.01
3,500C 17.77 21.15 251.33
5,000C 18.12 26.55 265.42
6,500C 18.79 26.01 271.33
2,000F 19.46 24.98 269.25
3,500F 20.43 28.21 315.22
5,000F 24.37 41.23 377.43
6,500F 29.34 48.55 431.22
The same with in the table 3, table 4 also shows acidic polysaccharose, saponin and total sugar content 6,500F is highly enriched.Compare with matched group, the acidic polysaccharose of institute's enrichment is up to 1.54 times, and saponin is up to 1.78 times, and total sugar is up to 1.57 times.Therefore, by control selecting crude drugs with winnower condition, the more effectively active component of enrichment Radix Ginseng.
Embodiment 2
Improve the establishment of the sorting condition of the Radix Ginseng powder amount of returning
The foregoing description 1 shows can be by the active component of selecting crude drugs with winnower enrichment Radix Ginseng.Yet 6, the Radix Ginseng powder amount that 500F and 5,000F obtain only is 9.5 weight % of used Radix Ginseng; Therefore, we attempt to improve the amount of returning of described powder.
That is, with 4, the hyperfine Radix Ginseng powder that 895g adopts embodiment 1 method milling with the method for embodiment 16,000rpm selecting crude drugs with winnower 2 times, 5,000rpm selecting crude drugs with winnower 2 times and 3, the 500rpm selecting crude drugs with winnower once (is seen: table 5).
When measuring the granularity of above-mentioned hyperfine Radix Ginseng powder, the intermediate value granularity is as follows: X 10=2.511 μ m, X 50=7.789 μ m and X 90=25.245 μ m.
[table 5]
The selecting crude drugs with winnower condition
Carry out the number of times of sorting 1 2 3 4 5
Processing capacity (kilogram/hour) 2.5 2.3 2.9 3.0 3.5
Separation velocity (rpm) 6,000 6,000 5,000 5,000 3,500
Pressure reduction (mmAq) 310 270 245 230 210
Air-supply equipment (Hz) 60 60 60 60 60
Running time (hour) 110 70 60 45 50
Result with the granularity of the methods analyst Radix Ginseng powder of embodiment 1 is as shown in table 6.
[table 6]
The granularity analysis of Radix Ginseng powder
Figure C200580011386D00091
As above shown in the table 6,4 times selecting crude drugs with winnower has obtained 1, and the Radix Ginseng fine powder of 110g accounts for the about 22.7 weight % through the Radix Ginseng powder of sorting.
Method by embodiment 1 is measured the content through content, polysaccharide and the saponin of the basis of the Radix Ginseng powder of sorting, and the result is respectively shown in table 7 and table 8.
[table 7]
Basis content (unit: weight %) through the Radix Ginseng powder of sorting
Sample Moisture Cinder Carbohydrate Crude protein
Matched group 8.25 4.69 77.11 14.55
The first time 6,000F 4.79 4.51 76.44 19.88
The second time 6,000F 5.09 4.65 76.45 19.35
The first time 5,000F 4.78 4.75 78.79 16.66
The second time 5,000F 5.10 4.48 79.23 15.86
3,500F 5.54 4.49 79.79 14.34
The first time 6,000C 6.38 4.23 79.34 13.99
The second time 6,000C 6.18 4.49 79.67 13.22
The first time 5,000C 6.19 4.42 79.89 13.44
The second time 5,000C 6.39 4.39 79.87 13.25
3,500C 5.92 4.29 80.79 13.02
[table 8]
Through the polysaccharide of the Radix Ginseng powder of sorting and the content (unit: mg/g) of saponin
Sample Acidic polysaccharose Saponin Total sugar
Matched group 16.38 34.38 229.67
The first time 6,000F 29.14 63.05 405.01
The second time 6,000F 27.87 51.28 399.22
The first time 5,000F 23.46 45.99 340.84
The second time 5,000F 21.79 40.50 317.30
3,500F 16.67 34.88 277.35
The first time 6,000C 19.24 36.45 274.52
The second time 6,000C 18.78 34.69 261.35
The first time 5,000C 18.01 33.21 258.27
The second time 5,000C 18.22 30.19 249.12
3,500C 17.45 30.00 241.44
As above shown in table 7 and the table 8, these results show the content of content, polysaccharide and saponin of the basis of Radix Ginseng 6,000F and 5,000F enrichment; Particularly 6,000F, the acidic polysaccharose of institute's enrichment up to about 1.78 times, saponin up to about 1.83 times, total sugar is up to about 1.76 times, this show described active component in this Radix Ginseng powder than the more effectively enrichment in the Radix Ginseng powder of sorting that in embodiment 1, obtains.
According to the abovementioned embodiments of the present invention 1 and 2, when be of a size of 1 μ m~Radix Ginseng powder of 100 μ m in aidr bells blast system with 5,000rpm~6, when 500rpm carried out sorting, the active component of Radix Ginseng obtained the most effective enrichment; Yet the above-mentioned separation wheel speed of aidr bells blast system depends on the size of this aidr bells blast system.
That is, have the aidr bells blast system that is different from the used size of the embodiment of the invention if use, then the separation velocity of separation wheel (rpm) will change according to the size of this aidr bells blast system.
For example, if adopt the aidr bells blast system that has greater than the used size of the present invention, even be lower than the separation wheel speed that the foregoing description 1 and 2 is adopted so, also can obtaining wherein, the active component of Radix Ginseng obtains the Radix Ginseng powder that the most effective enrichment is of a size of 1 μ m~9 μ m; If adopt the aidr bells blast system that has less than the used size of the present invention, so adopted faster than the foregoing description 1 and 25,000rpm~6, the speed of 500rpm, can obtaining wherein, the active component of Radix Ginseng obtains the Radix Ginseng powder that the most effective enrichment is of a size of 1 μ m~9 μ m.
To be limited in 1 μ m~9 μ m through the granularity of the Radix Ginseng powder of aidr bells blast system sorting, this is because reach 9 μ m or when bigger, the bioaccumulation efficiency of Radix Ginseng active component can reduce when the granularity through the Radix Ginseng powder of sorting.
In this, by using aidr bells blast system rather than separating and the Radix Ginseng powder that obtains to be of a size of 1 μ m~9 μ m is important by control separation wheel speed.
Industrial applicibility
Explain in detail and description such as above-mentioned institute, the present invention make by the dry method of utilizing grinding machine and aidr bells blast system rather than wet method obtain containing high level the ginseng active component hyperfine Ginseng Root Powder simple and easy and fast method become easily, described ginseng active component is such as being saponin(e, acidic polysaccharose, total reducing sugar and crude protein etc.; Therefore, the present invention can be widely used for improving use by the productivity of the various Ginseng Products of the Ginseng Root Powder of its gained.

Claims (2)

1. extract the method for the active component of Radix Ginseng by mechanical means, described method comprises: will put into kibbling mill and obtain the operation that fineness is 60~80 purpose ginseng granules through the Radix Ginseng of dehydration; The granule that so obtains is put into the single track aeropulverizer and obtained the operation that particle size is the hyperfine Radix Ginseng powder of 1 μ m~100 μ m; In aidr bells blast system, the powder that so obtains is carried out selecting crude drugs with winnower and obtains the operation that particle size is the powder of 1 μ m~9 μ m.
2. the method for claim 1 is characterized in that, described kibbling mill is a kind of in needle mill, impact mill, roller mill, vibratory bowl or the colloid mill.
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