CN100508880C - Electrical impedance scanning detection system and method of real-time multi-information extraction - Google Patents
Electrical impedance scanning detection system and method of real-time multi-information extraction Download PDFInfo
- Publication number
- CN100508880C CN100508880C CNB2007100186778A CN200710018677A CN100508880C CN 100508880 C CN100508880 C CN 100508880C CN B2007100186778 A CNB2007100186778 A CN B2007100186778A CN 200710018677 A CN200710018677 A CN 200710018677A CN 100508880 C CN100508880 C CN 100508880C
- Authority
- CN
- China
- Prior art keywords
- module
- electrical impedance
- data
- microprocessor
- frequency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
The invention discloses an electrical impedance scanning detection system for the withdrawal of real-time multi-information and the method thereof, wherein, the system comprises a PC machine, a data transmission interface module, a microprocessor, a control module, a data acquisition module, a preceding stage detection module, an excitation source and an exciting electrode; wherein, a detecting electrode array withdrawals a detection signal and sends the detection signal to the preceding stage detection module, the detection signal is sent to an A/D converter and a data buffer memory module corresponding to a data acquisition unit after passing through a current and voltage conversion module through a multiple way switch; the date buffer memory module enters into the microprocessor; the PC machine performs the data transmission, delivers a control command or revives date through the transmission interface module and a microprocessor module; a software with supporting data analysis, curve description, image display and information prompt is arranged in the PC machine; thereby obtaining the real-time electrical impedance information of a measured target body, the multiple frequency impedance information and the impedance property. The invention has the advantages that the detection accuracy is high, the processing speed is rapid, and the noise resistance ability is strong.
Description
Technical field
The invention belongs to biological tissue's electrical impedance detection range, particularly relate to a kind of in real time, can extract the electrical impedance scanning image-forming detecting system and the method for multiple electrical impedance information.
Background technology
It is by exciting electrode objective body to be applied certain range of excitation voltage that biological tissue's electrical impedance scanning detects, corresponding array detecting electrode detects tested regional body surface electric current, and on the analyzing and testing electrode unit electric current difference so that obtain the electrical impedance distribution of tested intra-zone.This detection method is generally used for interior tissue is existed the measurement of the objective body of big electrical impedance difference, and then obtains the electrical impedance information of different tissues.
Because be subjected to the restriction of detecting electrode array area, the electrical impedance scanning detection technique is divided into several zones with the objective body surface usually when target site is detected, and then each zone is detected respectively.Present detection system is because of its non real-time, and the operator places the surface of measured target body with detection probe, and the collection button that triggers on the probe is finished a frame imaging in this zone.Whether but usually because the operator can't judge it is that electrode surface does not contact well before pictorial display, or be region of interest under the electrode zone, the operator must trigger the measurement button repeatedly, and imaging is carried out in this zone, up to obtaining satisfied image.Set up the detection system of realtime imaging, the operator can see with the detecting electrode array and moving and the realtime imaging result that obtains helps to improve detection efficiency, and use that can the handled easily person.
Though present electrical impedance scanning imaging system can obtain under the multiple frequency imaging to target site, but the electrical impedance spectrum signature under the tested zone is not analyzed, it is the not well reflection of contact between these multifrequency imaging results, and the electrical impedance spectrum signature of tissue is the important information of identification different tissues, therefore is necessary to analyze the electrical impedance multi-frequency spectrum signature at measured target position.
The one-dimensional signal that detects of the electrical impedance electrical impedance characteristics rule over time that can react measured target body in addition, because of its one-dimensional signals of measured target body of different electrical impedance characteristicses may there are differences, therefore by also can obtain the electrical impedance characteristics of different tested tissue to the feature analysis of one dimension electrical impedance signal.The measuring ability that increases the one dimension electrical impedance information in the electrical impedance scanning system can provide more foundations for system discerns the detection of objective body.
Summary of the invention
Defective or deficiency at existing electrical impedance scanning existence, the objective of the invention is to propose a kind of electrical impedance scanning detection system and method for real-time many information retrievals, this system and method has the realtime imaging function, electrical impedance spectrum analysis function, and one dimension electrical impedance signal analysis function.
In order to realize above-mentioned task, the present invention takes following technical solution:
A kind of electrical impedance scanning detection system of real-time many information retrievals is characterized in that, this system mainly is made up of PC, data transmission interface module, microprocessor, control module, data acquisition module, prime detection module, driving source and exciting electrode; Microprocessor is connected with control module with data acquisition module respectively, is used for the data to control module transmitting control commands and processing collection; Data acquisition module is connected with the prime detection module, control unit is connected with driving source, prime detection module, data acquisition module respectively, amplitude output signal frequency to driving source is controlled, driving source is connected with exciting electrode, encouraged by the detecting electrode array of this exciting electrode to tested region surface setting, this detecting electrode array is connected with the prime detecting unit;
The detecting electrode array extracts detection signal, and data acquisition module is mainly to gathering from the analogue signal of prime detection module; And image data sent into data cache module, send into microprocessor by data cache module again; PC carries out transfer of data by coffret module and microprocessor module, sends control command or receives data; Have in the PC number of support according to one's analysis, curve describes, the software of pictorial display and information cue; And then obtain the electrical impedance distribution characteristic of measured target body.
Described prime detection module comprises current/voltage modular converter and variable connector, and variable connector carries out the switching of signal path by control module control.Described data acquisition module is provided with and corresponding A/D analog-digital converter of variable connector and data cache module, and microprocessor internal has digital demodulator, data buffer and instruction translator.
Described pumping signal adopts the numerical frequency synthetic method to realize, output multi-frequency and amplitude adjustable voltage signal.
Described data acquisition module is the collection of four-way high-speed parallel, and the digital signal input microprocessor module through collecting is carried out digital demodulation.
Described data transmission interface module be serial line interface UART, USB1.1 or Ethernet interface one of them, and carry out communication between the PC.
The method that the electrical impedance scanning that the electrical impedance scanning detection system of above-mentioned real-time many information retrievals is realized detects and electrical impedance characteristics is analyzed is characterized in that this method step is as follows:
1. set the detected parameters of hardware system according to detecting needs, or the using system default parameters;
2. according to the rate of scanning of default, under this frequency, utilize the detecting electrode array that real time scan is carried out on the surface of objective body and detect;
3. system produces and shows the realtime imaging result, shows the one dimension impedance variation curve of detecting electrode array correspondence simultaneously according to default;
4. according to the realtime imaging result, freeze interested image and preserve this image information constantly, the image of preserving is carried out graphical analysis, and carry out the identification of characteristic area;
5. to the zone of image of interest correspondence, carry out multi-frequency scanning, and preserve imaging results according to the frequency range of default;
6. according to the result of multi-frequency scanning, can obtain the electrical impedance spectral property curve of the surveyed area of each detecting electrode correspondence;
7. the detecting electrode array is placed area-of-interest, carry out successive signals collecting, and write down the one dimension impedance variation curve of each detecting electrode array correspondence;
8. one or more in the real time imaging information in the detected zone of analysis-by-synthesis, multiple spectra information, the one-dimensional signal feature are to assess the electrical impedance distribution feature in the tested zone.
When carrying out electrical impedance scanning, be provided with the target area is carried out the real time scan imaging successively according to system default, the record of multi-frequency scanning imaging and one dimension electrical impedance signal, perhaps select the real time scan imaging according to detecting needs, the multi-frequency scanning imaging, a kind of detection mode in the one dimension impedance record, perhaps any two kinds combination.
In realtime imaging, when the operator need write down the image in a certain moment, touch the freeze frame button, the single-frame images of inscribing during with this is preserved, so that the image of preserving is carried out graphical analysis, and carrying out the identification of characteristic area, system can store the images acquired in the fixed time section, this images acquired of playback when needing.
Described multiple spectra information comprises electrical impedance real part information, imaginary part information, the mould value information, phase information, and carry out the spectrum curve feature analysis of the anti-information of corresponding resistor, so that the spectral characteristic data that obtain on two or more detecting electrodes unit are carried out computing, as obtain another kind of data that more can the anti-feature of reflected resistance after averaging, subtracting each other;
Described one-dimensional signal feature comprises real part information, imaginary part information, and the mould value information, phase information, and carry out the one dimension curvilinear characteristic analysis of the anti-information of corresponding resistor, so that the one dimension impedance data that obtains on two or more detecting electrodes unit is carried out computing.
System of the present invention has advantages such as accuracy of detection height, processing speed is fast, anti-noise ability is strong.Its main feature of electrical impedance scanning detection method based on real-time many information retrievals of this system is: (1) system can realtime imaging and extract corresponding electrical impedance information as required, avoids traditional detection result's occasionality; (2) system's multiple spectra characteristic information that can extract tissue feature analysis of line correlation of going forward side by side; (3) system can extract the one dimension electrical impedance information of tissue, the anti-time dependent rule of reflection tissue resistance; (4) system can carry out analysis-by-synthesis with realtime imaging information, multiple spectra electrical impedance characteristic information and the one dimension electrical impedance characteristic information of tissue, to reflect the electrical impedance characteristics difference of different tissues in the tested zone more accurately.
Description of drawings
Fig. 1 is a system structure schematic diagram of the present invention;
Fig. 2 is the stimulating module structural representation;
Fig. 3 is the acquisition module structural representation;
Fig. 4 is the control module structural representation;
Fig. 5 is that the detecting electrode handle constitutes and functional schematic;
Fig. 6 is the software processes functional schematic;
Fig. 7 is an imaging features analyzing and processing sketch map;
Fig. 8 is an electrical impedance scanning multifrequency imaging example;
Fig. 9 is the electrical impedance spectral characteristic curve example that multi-frequency scans the breast portion that obtains down;
Figure 10 A is that the contact skin impedance increases corresponding one dimension electrical impedance curve in time
Figure 10 B is the one dimension electrical impedance curve of contact skin impedance stabilization state correspondence
Figure 11 is after electrical impedance mould value that two electrodes obtain is subtracted each other, the curve of its difference correspondence.
The present invention is described in further detail below in conjunction with drawings and Examples.
The specific embodiment
The electrical impedance scanning detection system of real-time many information retrievals that the present invention proposes, the system structure sketch map as shown in Figure 1.This system mainly is made up of PC, data transmission interface module, microprocessor, control module, data acquisition module, prime detection module, driving source and exciting electrode; Microprocessor is connected with control module with data acquisition module respectively, is used for the data to control module transmitting control commands and processing collection; Data acquisition module is connected with the prime detection module, control unit is connected with driving source, prime detection module, data acquisition module respectively, amplitude output signal frequency to driving source is controlled, driving source is connected with exciting electrode, encouraged by the detecting electrode array of this exciting electrode to tested region surface setting, this detecting electrode array is connected with the prime detecting unit;
The detecting electrode array extracts detection signal, and data acquisition module is mainly to gathering from the analogue signal of prime detection module; And image data sent into data cache module, send into microprocessor by data cache module again; PC carries out transfer of data by coffret module and microprocessor module, sends control command or receives data; Have in the PC number of support according to one's analysis, curve describes, the software of pictorial display and information cue; And then obtain the electrical impedance distribution characteristic of measured target body.
Described prime detection module comprises current/voltage modular converter and variable connector, and variable connector carries out the switching of signal path by control module control.Described data acquisition module is provided with and corresponding A/D analog-digital converter of variable connector and data cache module, and microprocessor internal has digital demodulator, data buffer and instruction translator.
System can adopt voltage drive, the current measurement mode; Also can adopt current excitation, the voltage measurement mode.Present embodiment is a voltage drive, the current measurement mode.Driving source can output AC variable ratio frequency changer voltage signal, puts on testee by exciting electrode.The placement location of exciting electrode changes according to the feature at tested position.The detecting electrode array is made of a plurality of small electrode unit of arranging by certain rule, and shown in Fig. 5 is the square electrode array element of a 11*11.The detecting electrode array places the surface of testee, is used to extract current signal.Multi-way current signal is converted to the voltage signal of multidiameter delay through current/voltage.The present embodiment design adopts variable connector to switch, and the plurality of voltages signal is transformed four road signals output to part of data acquisition, finishes the output of all signals by the control variable connector.The mode that adopts variable connector to switch can reduce the line between prime test section and the part of data acquisition.Can reduce simultaneously the passage that A/D gathers.Reach simultaneously the purpose of realtime imaging for the picking rate that improves system, present embodiment adopted four independently the high-speed a/d chip carry out data acquisition, the acquisition rate of chip is 800ksps under the normal mode, acquisition precision is 16.The data of gathering at first enter data buffer memory FIFO, under the control of microprocessor, data are read into microcontroller then, carry out date processing.Native system adopts modularized design, has used a slice fpga chip (EP1C3T144) to realize above-mentioned stimulating module in circuit, data acquisition module, the partial function of control module.Embedded microprocessor adopts an ARM7 chip (LPC2214) to realize in the present embodiment, and the data that are read into microprocessor can be carried out the digital demodulation processing, and digital demodulation is represented the electric conductivity value and the capacitance of tested regional undertissue electrical impedance characteristics.Final demodulation result is sent to PC.In native system, the data transmission interface between microprocessor and the PC has designed asynchronous serial port, USB interface, Ethernet interface.Can select appropriate interface as required, present embodiment has adopted USB interface in transfer of data.By USB interface, microprocessor is accepted the instruction from PC, deciphers the decoding of partly finishing instruction by instruction, and operates accordingly according to decode results.Control section in the system is mainly finished the control that driving source is exported according to the parameter that is provided with of system, to the control of variable connector part, to the control of data collection.Control section also according to the interrupt requests from hardware, is finished control corresponding simultaneously.PC mainly is that the data of importing into are wherein analyzed, and finishes as data analysis curve plotting, pictorial display, functions such as information cue as required.
Fig. 2 is the realization sketch map of hardware system driving source of the present invention, realize based on the numerical frequency composition principle in the system incentive source, comprise the variable frequency clock generator, wave memorizer, address generator, digital to analog converter, buffering operational amplifier, and signal processing circuits such as follow-up filtering, amplitude control.By control signal control variable frequency clock generator, thereby to change the frequency that digital to analog converter reads the frequency change output drive signal of Wave data.Wave memorizer and address generator part is realized by partial logic resource among the fpga chip EP1C3T14 in the hardware circuit and RAM resource in the present embodiment.Wherein the data in the wave memorizer are 16, and complete waveform is totally 1024 data; Analog-digital chip is AD9777, and its precision is 16, and speed is 160MSPS.
Fig. 3 is the sketch map that hardware system Acquisition Circuit of the present invention realizes, adopts 4 tunnel analog digital conversion passages that detection signal is carried out parallel acquisition in the present embodiment, and selected analog digital conversion (A/D) chip is AD7671, totally four.The AD7671 precision is 16, and the conversion speed maximum can reach 800kSPS.Under acquisition controlling, at first put into data buffer area from the image data of A/D chip.Acquisition control module in the present embodiment and image data buffer area module are realized by the partial logic resource of fpga chip (EP1C3T144).The data of gathering buffer area are read into chip internal by ARM chip LPC2214 then, carry out operation of data then and handle, and final result is sent into PC by data-interface.
Fig. 4 is the sketch map of hardware system control section of the present invention, and the mode that realizes control in the present embodiment reads order from PC for ARM chip (LPC2214) at first, and the result according to instruction decoding operates accordingly then.Because the fpga chip (EP1C3T144) in the present embodiment hardware circuit has a plurality of I/O resources, therefore the control of the major part of system is realized by the partial logic unit of fpga chip, wherein mainly comprise the control of variable frequency generator, excitation output control and signals collecting control.
Fig. 5 is a detection probe sketch map in the one embodiment of the invention.As shown in the figure, detection probe comprises the detecting electrode array, prestage testing circuit plate, control knob, and display lamp.Wherein control knob detects display lamp and also can place on the system control position.Wherein start scan button, control system begins objective body is carried out real time scan.Freezing button is used for freezing interested image in the real time scan process.Multi-frequency scanning pushbutton enable multi-frequency scanning function is carried out scanning imagery under the multi-frequency point to objective body.
When the system that embodiments of the invention are described, system carry out the electrical impedance detection to certain objective body, detect and the specifically enforcement according to the following steps of electrical impedance information analytical method:
(1) start enters the system parameter setting interface, can set the parameter of system as required, comprises the excitation output parameter, excitation output frequency, detecting pattern, multi-frequency scanning scope; If system were not set according to the acquiescence parameter work.
(2) position of constant excitation electrode is convenient detection to objective body, and detecting electrode can move at the region of interest field surface.
(3) enter detected state after system's initialization is finished, the detecting pattern of system is divided into following several mode:
A. many information retrievals detecting pattern at first starts the real time scan function, carries out the real time scan imaging with detecting electrode on the surface of area-of-interest.When moving to a certain position at detecting electrode when finding image of interest, use freezing function freeze frame and storage.Keep the detection probe invariant position, start the multi-frequency scanning button, multi-frequency point imaging under the set point is carried out in this zone, obtain the imaging results of a plurality of frequency lower areas.Draw the spectral characteristic curve of resultant electrical impedance information on each detecting electrode unit simultaneously.By analysis (the concrete analysis process sees below) to testing result under the different frequency, under frequency-of-interest, objective body is carried out real time scan, can write down resulting one dimension impedance characteristic under each detecting electrode unit simultaneously.Can analyze (the concrete analysis process sees below) to the one dimension impedance characteristic at last, to obtain more electrical impedance information.
B. the detecting pattern of real time scan imaging, the electrical impedance characteristics of some tested regional undertissue does not have significant difference to the variation of frequency or only need obtain the electrical impedance information of a certain frequency undertissue, therefore for this kind detected object, can only carry out the real time scan imaging.Under the detection frequency of system default, enter detected state after, start the real time scan function, in the mobile detection probe in testee surface, when finding image of interest, start freezing button simultaneously, freeze and memory image.
C. the detecting pattern of multi-frequency imaging, the electrical impedance characteristics of some tested regional inner tissue to changing there was no significant difference in time, therefore do not need to carry out the extraction of one dimension impedance information for this kind detected object in a short time.System starts the real time scan function after entering detected state, when finding image of interest, start freezing button, freeze and memory image, the electrical impedance scanning imaging under the multi-frequency point in the default frequency range is carried out at this position simultaneously, and analyze imaging results.
D. the detecting pattern of one-dimension information changes apparent in viewly in time for its interior tissue electrical impedance characteristics of some tested zone, it is even more important therefore to extract its one dimension electrical impedance information.After system enters detected state, the detecting electrode array is placed surface interested, start the one-dimension information writing function, then can write down the electrical impedance characteristic curve of each detecting electrode unit correspondence, as required one dimension electrical impedance curve is analyzed at last.
(4) according to the electrical impedance information analysis result that obtains under different detecting patterns, system provides corresponding information cue or information output.Adopt a kind of detecting pattern optional in the step (3) after objective body is finished detection, system analyzes the electrical impedance information that detection obtains, and analysis result is carried out computer screen demonstration or printout.
(5) after system finishes a detection task, enter the next item down and detect task, perhaps log off.
The system that the foregoing description is described, system have the real time imaging of carrying out and show record, freeze frame feature analysis, multifrequency feature analysis, one dimension curve record analytic function.Fig. 6 is the software function interface of embodiment of the invention descriptive system, comprises the systematic parameter setting section, real time imaging display part, freeze frame display part, multi-frequency image and curved portion, one dimension impedance curve display part.
The realization of systems soft ware major function and being described below:
(1) real time imaging Presentation Function
In the system that the invention described above embodiment describes, system has the sampling rate of per second 20 frames, and data are imported computer into through USB interface, and carry out the real-time demonstration of image.After starting the real time scan button, enter the real time imaging show state,, in the realtime imaging window shown in Fig. 6 software interface sketch map, show real-time electric conductance imaging (also changeable is the capacitance parameter image formation state) along with moving of detection probe.The operator can freeze the imaging in a certain moment as required, and stores this image, and simultaneity factor is stored freeze frame moment front and back totally 20 seconds real time imaging information automatically.The starting and ending of the storage realtime imaging that system also can be provided with according to software is stored the realtime imaging record that obtains in the corresponding time period constantly.System has the function of realtime imaging record playback, can be as required the realtime imaging record of a certain moment segment record be carried out playback and shows.
(2) image characteristic analysis processing capacity
In the system that the invention described above embodiment describes,, can use the image characteristic analysis processing capacity that image is carried out feature identification and further analysis for the single-frame images after freezing.In the present embodiment, can adopt the interference factor of filtering method removal of images, make the more clear demonstration of image.The image of describing in the present embodiment is a gray level image, and high being organized in is the clear zone and shows that the tissue that electrical conductivity is low is the dark space and shows in the gray level image for electrical conductivity.In to image characteristic analysis, use the characteristics of image recognition function, can discern the imaging region of high conductivity.Simultaneously adopt GTG display process processing method in the present embodiment, can strengthen demonstration, so that image readability directly perceived more image.In as Fig. 6 software interface, there is image characteristic analysis to handle window, the image that is primarily aimed at after freezing to store carries out feature analysis, by analysis the image after the identification can assist operator to the analysis of image, improve the efficient of interpreting blueprints, reduce interpreting blueprints person's subjective judgment.
(3) electrical impedance multi-frequency feature analyzing function
In the system that the invention described above embodiment describes, can in certain frequency band range, carry out the multi-frequency spot scan to a certain fixed area under the detecting electrode array.The electrical impedance characteristics of some tested regional inner tissue has the variation of significance with frequency change, therefore can find the characteristic frequency point of different tissues by multi-frequency scanning, promptly significant difference be arranged at the electrical impedance characteristics of this this tissue of Frequency point and the electrical impedance characteristics of other tissue.For the system of describing in the present embodiment, the frequency range that can detect is 100Hz～100kHz.When carrying out multi-frequency scanning 12,24 or 48 Frequency points can be set and carry out frequency scanning.After the rate of scanning parameter of the system of setting, start the multi-frequency scanning button in selected zone, enter the multi-frequency scanning state, finish multi-frequency scanning after, can obtain corresponding electrical impedance information image under the different frequency point.As multi-frequency image display window and multifrequency electrical impedance spectral curve display window are arranged in Fig. 6 software interface, in the multi-frequency image display window, the real part (resistance) that can show tested regional electrical impedance, imaginary part (electric capacity) image also can show the mould value image and the phase image of electrical impedance.The operator can show corresponding multifrequency electrical impedance scanning image as required.Simultaneously in multifrequency electrical impedance spectral curve display window, software can be drawn the multi-frequency impedance characteristic curve that extracts on each electrode unit, and be chosen on the software interface multifrequency electrical impedance characteristics curve that shows 4 electrode unit correspondences as required, what show among the figure is the variation relation of electrical impedance mould value with frequency, can show the mould value as required, phase place, or real part, imaginary part is with the variation relation of frequency.Be elaborated in conjunction with Fig. 9 (multifrequency characteristic curve) about the system multi-frequency feature analyzing function.
(4) one dimension electrical impedance characteristics tracing analysis
In the system that the invention described above embodiment describes, system has the function of record one dimension electrical impedance characteristics curve.
The one-dimensional signal feature comprises real part information, imaginary part information, and the mould value information, phase information, and carry out the one dimension curvilinear characteristic analysis of the anti-information of corresponding resistor, so that the one dimension impedance data that obtains on two or more detecting electrodes unit is carried out computing.
One dimension electrical impedance curve display electrical impedance characteristics parameter dynamic change procedure in time has conveniently, advantage intuitively.The electrical impedance characteristics of some measured target body is changed significantly in time, as the one dimension impedance bioelectrical measurement is carried out in the abundant zone of human body blood supply, can see that with the heart one dimension impedance bioelectrical measurement value of beating obvious variation is arranged.The one dimension electrical impedance curve record that causes with respiratory variations is similarly also arranged.Another aspect, the electrical impedance characteristics of biological tissue has obvious variation with temperature, humidity, therefore use one dimension electrical impedance characteristics curve also can the control measurement process in, whether measurement result is subjected to the influence of temperature and humidity.As one dimension electrical impedance curve display window is arranged in Fig. 6 software interface, software can be drawn the one dimension electrical impedance characteristics curve that extracts on each electrode unit, and is chosen in the one dimension electrical impedance characteristics curve that shows 4 electrode unit correspondences on the software interface as required.What show among the figure concerns over time for electrical impedance mould value, can show electrical impedance mould value as required, phase place, or real part, and imaginary part concerns over time.The function of analyzing about system one dimension electrical impedance characteristics is in conjunction with Figure 10, and Figure 11 is described in detail.
(5) analysis-by-synthesis of multiple electrical impedance information
In order effectively to distinguish the difference of different tissues electrical impedance characteristics under the tested zone, need sometimes multiple impedance information analysis-by-synthesis.Be about to the electrical impedance images feature difference, spectral characteristic difference, one dimension impedance variation trend difference analysis-by-synthesis is according to the electrical impedance characteristics difference of Comprehensive analysis results differentiation different tissues.
Fig. 7 is that image characteristic analysis is handled example, 7A is the original measurement electrical impedance real part image that system acquisition arrives among the figure, noise spot with a high brightness, because other useful information in the image has been flooded in the existence of noise spot, adopt filtering algorithm, the noise spot filtering can be made the useful information reduction of image.Fig. 7 B is the image through obtaining after the filtering, the imaging of the corresponding high conductivity objective body in speck zone in the image, adopt characteristics of image identification speck zone in the image can be discerned, distinguishing high conductivity target and low conductivity target, 7C carries out the image that obtains behind the feature analysis to original image.
Fig. 8 is a plurality of images that collect under the multi-frequency.Be respectively at 200Hz 500Hz, 1kHz, 5kHz, 10kHz, the electrical impedance real part that obtains under the 20kHz respective frequencies and the imaging results of imaginary part.The result can see from figure, and the speck region area in the electrical impedance real part image diminishes along with the increase of frequency, and in the corresponding imaginary part imaging results, along with the increase of frequency, the speck zone disappears.The electrical impedance real part property difference that low frequency time domain inner tissue is described is bigger, and the real part property difference that increases electrical impedance with frequency reduces, therefore at the low-frequency range different tissues in the distinguishable region preferably.
Fig. 9 is the electrical impedance spectral characteristic curve that multi-frequency scans the breast portion that obtains down.Shown the EIS data frequency characteristic curve that covers teat tissue among the figure, its mid point wire list shows the frequency curve of a certain electrode position in the normal surrounding tissue, and the triangle line is represented the frequency curve of teat tissue.The frequency curve of teat tissue numerically is woven with significant difference with normal group, and two curves are also having bigger difference in shape.The electric conductance real part and the amplitude integral body of teat tissue are bigger, and when frequency was higher, the slope of its rising significantly diminished, and was tending towards saturated; (f＜3000Hz) be higher than normal structure to compare then drops to when high frequency below the normal structure electric conductance imaginary part of teat tissue, the intersection of two curves occurs when low frequency; And its corner frequency (f=992Hz) is obviously lower; The electric conductance phase curve of teat tissue is not to descend earlier to rising again, but dull always the rising.
Figure 10 is the one dimension electrical impedance characteristics curve of electrode-contact skin impedance variation correspondence.Figure 10 A and Figure 10 B are respectively the one dimension electrical impedance characteristics curve of two electrode unit correspondences in the electrod-array.In Figure 10 A, can see, along with the increase of time, the one dimension electrical impedance mould value that records on this electrode unit increases, and reason is that the conductive paste between electrode and the testee surface becomes dry, cause contact impedance to increase, therefore obtain the one dimension electrical impedance curve shown in Figure 10 A.One dimension electrical impedance curve among Figure 10 B is then milder, illustrates in time to change, and the impedance value that this electrode unit records does not have significant change.Because system can record the one dimension impedance characteristic of each electrode unit correspondence in the electrod-array simultaneously, so when analyzing, feature that can comprehensive a plurality of curves is perhaps carried out certain calculation and obtained having more the curve that the reaction impedance of feature changes.Figure 11 promptly is that its difference was with respect to the curve of the variable quantity correspondence of an original measurement value after the electrical impedance mould value that two electrodes obtain was subtracted each other.Can see can the reaction resistance anti-variation with heart beating of this curve from curve, the pump blood that can be interpreted as heart makes the electrical impedance mould value reduction of the abundant tissue of corresponding blood supply detecting electrode the unit under.
The present invention compared with prior art has following technique effect:
In existing electrical impedance scanning detection method for the biology tissue, do not adopt real-time imaging skill Art is by repeatedly single frames measurement to area-of-interest, keeps at last the satisfied image of a width of cloth, because lack In real time imaging prompting, this kind detection method contingency is big, usually because electrod-array and objective body surface connect Tactile bad, and need repeated measurement. Simultaneously existing electrical impedance scanning detection method extract organism (as Human body) during tested regional electrical impedance information, only pay close attention to the image under a certain fixed frequency, perhaps multiple The independent image that obtains respectively under the frequency. The line combining image of electrical impedance that records under the multifrequency not being set a song to music letter Breath is analyzed, and also a dimension electrical impedance information combination is not analyzed, and some can be utilized Electrical impedance feature information is not excavated and comprehensive the use. The present invention adopts the mode of real-time imaging to survey Amount, the operator can freeze interested image under picture cues, reduced the contingency that detects. With The time system with the electrical impedance images information of tested regional inner tissue, multiple spectra curve characteristic and a dimension are in real time Electrical impedance information combines and analyzes, and can provide for the tissue of distinguishing different electrical impedance characteristicses sufficient Information improves the ability of distinguishing different tissues.
Claims (2)
1. the electrical impedance scanning detection system of real-time many information retrievals is characterized in that, this system mainly is made up of PC, data transmission interface module, microprocessor, control module, data acquisition module, prime detection module, driving source and exciting electrode; Microprocessor is connected with control module with data acquisition module respectively, is used for the data to control module transmitting control commands and processing collection; Data acquisition module is connected with the prime detection module, control unit is connected with driving source, prime detection module, data acquisition module respectively, amplitude output signal frequency to driving source is controlled, driving source is connected with exciting electrode, encouraged by the detecting electrode array of this exciting electrode to tested region surface setting, this detecting electrode array is connected with the prime detecting unit;
The detecting electrode array extracts detection signal, and data acquisition module is mainly to gathering from the analogue signal of prime detection module; And image data sent into data cache module, send into microprocessor by data cache module again; PC carries out transfer of data by coffret module and microprocessor module, sends control command or receives data; Have in the PC number of support according to one's analysis, curve describes, the software of pictorial display and information cue; And then obtain the electrical impedance distribution characteristic of measured target body;
Described prime detection module comprises current/voltage modular converter and variable connector, and variable connector carries out the switching of signal path by control module control;
Described data acquisition module is provided with and corresponding A/D analog-digital converter of variable connector and data cache module, and microprocessor internal has digital demodulator, data buffer and instruction translator;
Described pumping signal adopts the numerical frequency synthetic method to realize, output multi-frequency and amplitude adjustable voltage signal;
Described data acquisition module is the collection of four-way high-speed parallel, and the digital signal input microprocessor through collecting carries out digital demodulation.
2. the electrical impedance scanning detection system of real-time many information retrievals as claimed in claim 1 is characterized in that, described data transmission interface module be serial line interface UART, USB1.1 or Ethernet interface one of them, and carry out communication between the PC.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100186778A CN100508880C (en) | 2007-09-17 | 2007-09-17 | Electrical impedance scanning detection system and method of real-time multi-information extraction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100186778A CN100508880C (en) | 2007-09-17 | 2007-09-17 | Electrical impedance scanning detection system and method of real-time multi-information extraction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101156776A CN101156776A (en) | 2008-04-09 |
| CN100508880C true CN100508880C (en) | 2009-07-08 |
Family
ID=39305116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2007100186778A Expired - Fee Related CN100508880C (en) | 2007-09-17 | 2007-09-17 | Electrical impedance scanning detection system and method of real-time multi-information extraction |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100508880C (en) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370480A (en) * | 2011-09-30 | 2012-03-14 | 中国人民解放军第四军医大学 | Impedance detection device and detection method for craniocerebral radiation therapy treatment |
| CN102379697B (en) * | 2011-10-12 | 2012-10-24 | 中国人民解放军第四军医大学 | Detection device and calibration method for scanning and imaging pre-signal conditioning module by electrical impedance |
| US9445741B2 (en) * | 2011-10-31 | 2016-09-20 | General Electric Company | System and method for beamforming in soft-field tomography |
| CN102512169B (en) * | 2011-12-31 | 2013-06-05 | 重庆邮电大学 | Adaptive control method and device for deviation in skin electrical signal testing |
| CN102579044B (en) * | 2012-02-27 | 2013-07-10 | 天津大学 | Electrical impedance imaging system of exciting and acquisition dual-scanning mode and information acquisition method thereof |
| CN102727183A (en) * | 2012-06-14 | 2012-10-17 | 深圳市元征科技股份有限公司 | Device for detecting cell vigor |
| CN103054578B (en) * | 2013-01-24 | 2015-04-01 | 四川大学 | Meridian point search tester |
| CN103190907B (en) * | 2013-04-17 | 2015-02-18 | 深圳大学 | Impedance-analysis-based vocal cord detecting device and impedance-analysis-based signal detecting method |
| CN103235190B (en) * | 2013-04-19 | 2015-10-28 | 重庆金山科技（集团）有限公司 | A kind of impedance test method |
| CN103267884A (en) * | 2013-05-11 | 2013-08-28 | 桂林理工大学 | Leakage current detection device for bipolar square-wave pulse voltage insulation life test |
| CN103690166B (en) * | 2013-12-16 | 2016-06-08 | 天津科技大学 | A kind of anti-imaging system of respiratory three-dimensional resistance based on PXI bus and formation method thereof |
| GB2524470B (en) * | 2014-02-16 | 2019-04-17 | Wang Wei | An apparatus and method for "high-resolution" electrical impedance imaging |
| TWI563972B (en) * | 2014-06-11 | 2017-01-01 | 國立成功大學 | Signal process system and method for the same and bioimpedance detection device and element |
| CN104007322B (en) * | 2014-06-12 | 2017-05-17 | 中国人民解放军第四军医大学 | High-precision data acquisition system for electrical impedance imaging |
| CN105708457A (en) * | 2014-12-05 | 2016-06-29 | 中国人民解放军第三军医大学第三附属医院 | Cardio-pulmonary resuscitation monitoring method and system |
| CN104905787B (en) * | 2015-04-30 | 2017-06-16 | 中国人民解放军第三军医大学第二附属医院 | The apparatus for evaluating and method of peripheral tissues' impedance spectrum characteristic that cardiac impedance extreme value drives |
| CN105023412B (en) * | 2015-07-06 | 2018-06-15 | 成都科力德科技有限责任公司 | Collecting sensor signal device |
| CN105403595B (en) * | 2015-12-22 | 2018-06-22 | 北京交通大学 | Stem tuber resistance imaging data based on FPGA obtains system |
| GB2553261B (en) * | 2016-05-31 | 2022-05-04 | Wang Wei | Electrical impedance measurement and EIT image for location of a micro bio-channel under skin |
| CN106093632B (en) * | 2016-06-03 | 2018-11-06 | 温州大学 | The IP address setting method and system of electronic equipment position are tested based on scanning |
| CN106618568B (en) * | 2016-10-12 | 2020-05-12 | 西安石油大学 | Rapid EIS (electronic impedance spectroscopy) mixing measuring device applied to breast cancer detection |
| CN107228854A (en) * | 2017-06-26 | 2017-10-03 | 河北百强医用设备制造有限公司 | Using the tidal air Volatile Organic Components automatic detection device and its detection method of optical camera |
| CN109717868A (en) * | 2018-12-25 | 2019-05-07 | 武汉中科科理光电技术有限公司 | Radio frequency detects imaging device and method |
| CN109528306B (en) * | 2019-01-08 | 2020-09-15 | 华北电力大学（保定） | Electromagnetic/resistance bimodal imaging device for guiding hip joint replacement revision surgery |
| CN212015588U (en) * | 2019-04-04 | 2020-11-27 | 经纬泰和健康产业投资控股（北京）有限公司 | Detection equipment based on biomedical electrical impedance imaging technology and health risk assessment system |
| CN110200628A (en) * | 2019-05-13 | 2019-09-06 | 南京航空航天大学 | A kind of portable impedance detection system |
| CN110279416A (en) * | 2019-05-20 | 2019-09-27 | 南京航空航天大学 | A kind of portable impedance imaging system and its working method based on FPGA |
| CN110367984B (en) * | 2019-07-08 | 2022-11-08 | 中国人民解放军第四军医大学 | Electrical impedance scanning imaging detection probe with gradient sensitivity |
| CN112734909B (en) * | 2020-12-31 | 2022-02-01 | 杭州堃博生物科技有限公司 | Radio frequency operation prompting method, electronic device and computer readable storage medium |
| CN112529016A (en) * | 2020-12-21 | 2021-03-19 | 浙江欣奕华智能科技有限公司 | Method and device for extracting feature points in image |
| CN113040741A (en) * | 2021-03-01 | 2021-06-29 | 中国农业大学 | Multi-frequency electrical impedance imaging method and system for crop root zone |
| CN114137033A (en) * | 2021-11-25 | 2022-03-04 | 常州先趋医疗科技有限公司 | Method and apparatus for detecting target analyte |
| CN114632559B (en) * | 2022-01-26 | 2023-03-31 | 浙江大学 | On-chip micro-groove array digital PCR chip based on electrical impedance detection and manufacturing method thereof |
| CN116509368B (en) * | 2023-03-02 | 2024-02-09 | 南京航空航天大学 | Bimodal coupling detection system, method and storage medium based on electrical impedance and ultrasound |
-
2007
- 2007-09-17 CN CNB2007100186778A patent/CN100508880C/en not_active Expired - Fee Related
Non-Patent Citations (4)
| Title |
|---|
| 人体复阻抗断层成像系统. 王化祥，曲志刚，魏娟.医疗卫生装备，第3期. 2004 |
| 人体复阻抗断层成像系统. 王化祥，曲志刚，魏娟.医疗卫生装备，第3期. 2004 * |
| 数字化生物电阻抗成像系统. 曲志刚，王化祥，靳世久.电子测量与仪器学报，第20卷第4期. 2006 |
| 数字化生物电阻抗成像系统. 曲志刚，王化祥，靳世久.电子测量与仪器学报，第20卷第4期. 2006 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101156776A (en) | 2008-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100508880C (en) | Electrical impedance scanning detection system and method of real-time multi-information extraction | |
| KR102411010B1 (en) | 3d gesture recognition | |
| TWI652628B (en) | Method and device for fingerprint recognition | |
| CN111553307B (en) | Gesture recognition system fusing bioelectrical impedance information and myoelectric information | |
| CN107710225B (en) | Fingerprint acquisition apparatus and method therein for noise measuring | |
| JP5886211B2 (en) | Electronic imaging device using impedance sensor grid array mounted on or around the switch | |
| US20120293404A1 (en) | Low Cost Embedded Touchless Gesture Sensor | |
| US20190374156A1 (en) | Skin detection device and product information determination method, device and system | |
| CN102341039A (en) | Method and apparatus for diagnosing a diseased condition in tissue of a subject | |
| CN102879763B (en) | System and method for quickly positioning noise source through image identification and sound intensity scanning | |
| CN1720001A (en) | Live finger detection by four-point measurement of complex impedance | |
| US10635797B2 (en) | Method and electronic device for determining whether to allow user access | |
| CA2858409C (en) | Imaging apparatus | |
| CN112099624B (en) | Multimode diamond-shaped frame type capacitive sensing gesture recognition system | |
| CN110325951A (en) | Classification method and fingerprint sensing system are touched according to the finger of finger pressure | |
| CN107169427A (en) | One kind is applied to psychologic face recognition method and device | |
| CN102496032B (en) | Electrical equipment X ray digital image processing algorithm support system | |
| US20180120425A1 (en) | Ultrasound Testing | |
| CN106326869A (en) | Fingerprint identification method, device and mobile terminal | |
| CN104345979B (en) | Touch panel, information recording carrier and information acquisition method | |
| CN107102190A (en) | A kind of triboelectricity measuring system and its analysis method based on Labview | |
| CN113792587A (en) | Method and device for acquiring and identifying image, storage medium and electronic equipment | |
| CN110308821A (en) | Touch-control response method and electronic equipment | |
| CN107148117A (en) | Lighting Control Assembly, device and method | |
| CN206977750U (en) | Lighting Control Assembly and device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090708 Termination date: 20210917 |