CN100462360C - N-cyclohexyl-5-(4-chlorobutyl)-1H-tetrazole synthesis method - Google Patents
N-cyclohexyl-5-(4-chlorobutyl)-1H-tetrazole synthesis method Download PDFInfo
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- CN100462360C CN100462360C CNB2005100288043A CN200510028804A CN100462360C CN 100462360 C CN100462360 C CN 100462360C CN B2005100288043 A CNB2005100288043 A CN B2005100288043A CN 200510028804 A CN200510028804 A CN 200510028804A CN 100462360 C CN100462360 C CN 100462360C
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- cyclohexyl
- chlorobutyl
- tetrazole
- chloro
- synthetic method
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- Plural Heterocyclic Compounds (AREA)
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CNB2005100288043A CN100462360C (en) | 2005-08-15 | 2005-08-15 | N-cyclohexyl-5-(4-chlorobutyl)-1H-tetrazole synthesis method |
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CNB2005100288043A CN100462360C (en) | 2005-08-15 | 2005-08-15 | N-cyclohexyl-5-(4-chlorobutyl)-1H-tetrazole synthesis method |
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CN1733743A CN1733743A (en) | 2006-02-15 |
CN100462360C true CN100462360C (en) | 2009-02-18 |
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CNB2005100288043A Expired - Fee Related CN100462360C (en) | 2005-08-15 | 2005-08-15 | N-cyclohexyl-5-(4-chlorobutyl)-1H-tetrazole synthesis method |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102906075B (en) * | 2010-03-12 | 2016-01-13 | 拜耳知识产权有限责任公司 | The preparation method of the 1-alkyl tetrazolium that 5-replaces |
CN107266330A (en) * | 2017-07-20 | 2017-10-20 | 上海立科化学科技有限公司 | A kind of 5 chlorine N cyclohexyl pentanamide synthetic methods |
CN111233777A (en) * | 2020-03-31 | 2020-06-05 | 上海立科药物化学有限公司 | Synthesis method of N-cyclohexyl-5- (4-chlorobutyl) -1H-tetrazole |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4277479A (en) * | 1978-09-01 | 1981-07-07 | Otsuka Pharmaceutical Co., Ltd. | Tetrazolylalkoxycarbostyril derivatives and pharmaceutical compositions containing them |
WO2005019204A1 (en) * | 2003-08-26 | 2005-03-03 | Dipharma S.P.A. | A process for the preparation of cilostazol and of the intermediates thereof |
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2005
- 2005-08-15 CN CNB2005100288043A patent/CN100462360C/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4277479A (en) * | 1978-09-01 | 1981-07-07 | Otsuka Pharmaceutical Co., Ltd. | Tetrazolylalkoxycarbostyril derivatives and pharmaceutical compositions containing them |
WO2005019204A1 (en) * | 2003-08-26 | 2005-03-03 | Dipharma S.P.A. | A process for the preparation of cilostazol and of the intermediates thereof |
Non-Patent Citations (4)
Title |
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医药新品种西洛他唑的合成研究. 唐传久等.安徽化工,第3期. 2004 |
医药新品种西洛他唑的合成研究. 唐传久等.安徽化工,第3期. 2004 * |
血小板阻聚药物中间体N-环己基-5-氯丁基-1H-四氮唑的合成. 贾义霞等.合成化学,第11卷第(2)期. 2003 |
血小板阻聚药物中间体N-环己基-5-氯丁基-1H-四氮唑的合成. 贾义霞等.合成化学,第11卷第(2)期. 2003 * |
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CN1733743A (en) | 2006-02-15 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee | ||
CP03 | Change of name, title or address |
Address after: Room 6, building 3727, No. 201, south highway, Pudong New Area, Shanghai Patentee after: Like Medicine Chemistry Co., Ltd., Shanghai Address before: No. 329, Lane 17, Luding Road, Shanghai, Putuo District Patentee before: Like Medicine Chemistry Co., Ltd., Shanghai |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: N- -5- (Ding Ji 4- cyclohexyl chloride) synthesis method of -1H- tetrazole Effective date of registration: 20100301 Granted publication date: 20090218 Pledgee: Pudong Productivity Promotion Center, Shanghai Pledgor: Like Medicine Chemistry Co., Ltd., Shanghai Registration number: 2010990000713 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20110314 Granted publication date: 20090218 Pledgee: Pudong Productivity Promotion Center, Shanghai Pledgor: Like Medicine Chemistry Co., Ltd., Shanghai Registration number: 2010990000713 |
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C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090218 Termination date: 20100815 |