CN100459943C - Method for acquiring bioinformation using millimeter-wave band electromagnetic wave, device for acquiring and displaying bioinformation - Google Patents

Method for acquiring bioinformation using millimeter-wave band electromagnetic wave, device for acquiring and displaying bioinformation Download PDF

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Publication number
CN100459943C
CN100459943C CNB2005800232440A CN200580023244A CN100459943C CN 100459943 C CN100459943 C CN 100459943C CN B2005800232440 A CNB2005800232440 A CN B2005800232440A CN 200580023244 A CN200580023244 A CN 200580023244A CN 100459943 C CN100459943 C CN 100459943C
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organism
electromagnetic wave
meridian
electromagnetic
unit
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CN1984608A (en
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岩松诚一
丸井智敬
川口伸明
篠崎真
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Intellectual Property Bank Corp
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Intellectual Property Bank Corp
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Abstract

A method and device for extracting medically effective information by applying a millimeter-wave band electromagnetic wave to an organism and analyzing transmission, reflection and spontaneous radiation signals. The method and display comprise an acquiring step or means in which a database is so prepared in advance that from the transmission, reflection, and spontaneous electromagnetic wave data measured in a state that an organism is irradiated with an electromagnetic wave having wavelength components the wavelengths of which are 6 to 14 mm and a state that the organism is not irradiated, electromagnetic characteristics at the organism surface and in the organism is categorized and organized by actual condition of the organism constituent element, and the actual condition information on the organism constituent element of the subject is acquired according to the database information from the transmission, reflection, and spontaneous electromagnetic wave data measured in a state that the organism, the subject, is irradiated with a similar electromagnetic wave and a state that the organism is not irradiated; a step of associating the position information on the measurement portion of the subject with three-dimensional meridians and meridian points; and an image displaying step.

Description

Adopted the electromagnetic device that obtains and show Biont information of millimere-wave band
Technical field
The present invention is electromagnetic wave image analytical method and the device that a kind of bio-tissue is used, it possesses plural analytic unit, this analytic unit is at least one of following two kinds of analytic units, wherein, a kind of analytic unit have the electromagnetic illumination unit in millimeter wave zone and see through, the receiving element of reflection, spontaneous radiation; Another kind of analytic unit does not have the electromagnetic wave irradiation unit and only is made of the spontaneous electromagnetic receiving element that receives from as the bio-tissue of a corpse or other object for laboratory examination and chemical testing; and; by having the computer of suitable interface; signal from above-mentioned receiving element is synthesized and Flame Image Process and showing; and the unusual or three dimensional structure of bio-tissue, cross-section structure, surface texture etc. are carried out pictorial display, therefore be applicable to early diagnosis to the observation of human and animal's etc. tissue and various diseases, preventive assessment, treatment etc.
Background technology
As medical image method of diagnosis and device, ultrasound wave echological diagnosis method and device, tomography X method and device (X ray CT), Pumping Magnetic Resonance Method and device (MRI), positron emission Photographic technique and device (PET) etc. were arranged and extensively popularize in the past.
On the other hand, electromagnetic wave not only comprises the so-called electric wave that is used for radar or communication, also comprises than the electric wave light and the X ray (roentgen radiation) of high frequency far away.As medical instrumentation and the known utilization that X ray is arranged, but also known the zone of having adopted light and the medical instrumentation technology (with reference to patent documentation 1, patent documentation 2, patent documentation 3) in terahertz (THz) zone arranged.
Certainly, also known have a medical instrumentation (with reference to patent documentation 4, patent documentation 5, patent documentation 6) that has adopted so-called electric wave zone.Particularly, also known have: electromagnetic wave is ultra broadband (UWB:Ultra Wide Band) electromagnetic wave, and uses it can carry out medical instrumentation (with reference to patent documentation 7, patent documentation 8, patent documentation 9).Here, the ultra wide band electrically magnetic wave is meant the electromagnetic wave that has from the transmission band of mid frequency more than 25% or more than the 1.5GHz of signal.In patent documentation 9, also record: receive the echo of the electromagnetic pulse of vibration generation, and obtain medically useful image and be used for diagnosis from this signal.In addition, in patent documentation 12, disclose method and apparatus as follows: the electromagnetic wave of irradiation characteristic frequency (430-480MHz and multiple thereof), and observe absorption line and frequency shifting by this irradiation produced with the electromagnetism arrangements for analyzing frequency, and obtain the information relevant with the anisotropy of bio-tissue, thereby to a lot of bio-tissues assessments such as human and action have or not female chest unusual, unusual on the pathology such as agenosomia, cancer arranged.
In the general electromagnetic wave zone more than 10GHz, the accumulation of organism data is less.With respect to this, for (is the rank of " m " or " cm " with wavelength) about from the 1MHz frequency band to 10GHz, cancerous tumor cell and Normocellular electrical characteristics data have been accumulated, so also can carry out medical diagnosis as patent documentation 5, patent documentation 6.But, also do not possess the organism data that has surpassing under the frequency that wavelength is other 10GHz of " mm " level.Therefore, these medical image method of diagnosis and devices in the past have as follows problem, that is, resolution is low, to organism cause that radiation injury, Diagnostic Time are long, device costliness and diagnostic fees uprise etc.Especially be example as an example and with the cancerous diagnose, mostly the cancer of then utilizing present above-mentioned medical diagnosis method of popularizing and device to find is middle and advanced stage, in addition, although the pathological changes at early discovery initial stage is the key of treatment, realize that it is but very difficult.The resolution of above-mentioned medical diagnosis method and device is meticulous more also several mm, so the pathological changes at the initial stage about a few μ of early discovery m to 1mm is very difficult.
On the other hand, the also known technology that has use millimetre-wave radar device to improve the accuracy of detection of object of observation.For example, patent documentation 11 be relevant be used for observing the vehicle of travels down or be used to survey ground Rhizoma Anemones flaccidae, survey the content of resource.But,,, and also do not carry out open to it because the reason that does not possess organism data is as described above arranged about the millimeter wave electromagnetic wave being used in the content of medical imaging imaging yet.
But, the acquisition methods of above-mentioned Biont information be a kind of from shine to organism institute's instrumentation under the electromagnetic state to see through the method that electromagnetic wave and reflected electromagnetic wave datum " on one's own initiative " measure Biont information.With respect to this, also known have a kind of from do not shine to organism " passively " instrumentation under the electromagnetic state to spontaneous radiation electromagnetic wave data obtain the method for Biont information.The spontaneous radiation electromagnetic wave is a kind of electromagenetic wave radiation of region of ultra-red of so-called hot line, and can obtain depending on the information of the temperature of organism.Known moisture recorder (thermograph), thermoviewer surface temperature distribution imagers (imager) such as (thermoviewer) are exactly the instrument that utilizes it.These can be described as the information imaging device of organism surface surface temperature.
In the patent documentation 10 of the electromagnetic imaging device of relevant spontaneous radiation, disclose a kind of method as follows, promptly, from obtaining organism temperature inside information, thereby understand the existence of tumor and the method for intravital metabolic activity as the electromagnetic ultrared radiant intensity data of spontaneous radiation.This is a kind of such method, promptly, the intravital temperature propagation phenomenon of biology is replaced into circuit and makes both approximate, and the information of coming to obtain conversely the heat source position of organism inside by this circuit model, thereby the method for heat outputting source distribution image from the spontaneous radiation electromagnetic wave data of organism.But this invention can only be understood the ANOMALOUS VARIATIONS of the heat of surface, and can not carry out pictorial display to three dimensional structure.
Patent documentation 13 (the flat 10-192282 of TOHKEMY) is a kind of device as follows, promptly, by to tooth or skeleton irradiation electromagnetic wave and by radiating reflection or the electromagnetic wave that sees through is taken or by irradiation is taken by radiating electromagnetic wave, and can detect the whether healthy device of organism.Though as employed electromagnetic wave and the infrared ray of having given an example, but also can adopt coherent light and incoherent lights such as ultraviolet, visible light, radio wave, X ray, gamma-rays.Employed electromagnetic wave is not limited.Do not mention that relevant which type of electromagnetic wave is the content of effect how.
Patent documentation 14 (TOHKEMY 2002-248088) is invention as follows, promptly, by to first through cave emission hyperfrequency (UHF) electromagnetic wave and detect from second through the radiating electromagnetic wave in cave, and from two through between the cave the conductivity of signal or the invention of the state that dielectric constant is diagnosed out organ.In this invention is instrumentation between for 2 o'clock, rather than the instrumentation of the plane or stereo structure that whole human body is carried out.
Patent documentation 15 (TOHKEMY 2003-294535) be a kind of relevant as follows device and the invention of method, promptly, reception from human body radiating electromagnetic wave and measure the conductivity or the dielectric constant at position, and conductivity or dielectric constant be transformed to temperature, thereby measure the device and the method for the temperature at this mensuration position.But this is the invention that the specific part of human body is measured, rather than whole body is carried out the invention of instrumentation with plane or stereo structure.
In addition, in patent documentation 16 (TOHKEMY 2001-14446), patent documentation 17 (JP2004-180932), patent documentation 18 (2003-190101) etc., disclose a kind of for carrying out synthetic method by the same position of the resulting image of a plurality of medical image devices.
No. the 1911906th, patent documentation 1:JP patent " light layer image imaging device ", New Technology Enterprise Corp. etc.
No. the 3365397th, patent documentation 2:JP patent " many radio frequency channels light measuring device ", Shimadzu Scisakusho Ltd
Patent documentation 3: No. 00/50859, International Application No. WO " Method and apparatus for TeraHerzImaging ", Toshiba Research Europe Ltd.
Patent documentation 4: No. 6448788 " Fixed array microwave imagingapparatus and method " Microwave Imaging System Technologies of United States Patent (USP), Inc.
Patent documentation 5: No. 6421550 " Microwave discrimination betweenmalignant and benign breast tumors " INTERSTITIAL INC. of United States Patent (USP)
Patent documentation 6: No. 6061589 " Microwave antenna for cancer detectionsystem " INTERSTITIAL INC. of United States Patent (USP)
Patent documentation 7: No. 5361070 " Ultra-wideband radar motion sensor " Regents of the University of United States Patent (USP) of California
Patent documentation 8: U.S.'s publication 2003/0090407 " Ultra-wideband imaging system " Santhoff, John H.
Patent documentation 9: No. 01/18533 " Radar Apparatus for Imagingand/or Spectrometric Analysis and Methods of Performing Imaging and/orSpectrometric Analysis of a Substance for Dimensional Measurement, Identification and Precision Radar Mapping " Stove George Colin of International Application No. WO
Patent documentation 10: No. 6023637 " Method and apparatus for thermalradiation imaging " Liu of United States Patent (USP), et al
Patent documentation 11:JP spy opens " image processing apparatus and method thereof " Panasonic Electric Equipment Industrial Co.,Ltd 2003-299066 number
The special table of patent documentation 12:JP 2003-530902 " with the anisotropic emi analysis device in the system of chemical mode formation " Vedruccio (ベ De Le ッ チ ョ), and Clarbruno (Network ラ Le Block Le-ノ)
Patent documentation 13:JP spy opens flat 10-192282 " the organism diagnostic equipment " Co., Ltd.'s river and mountain
Patent documentation 14:JP spy opens 2002-248088 " the organism diagnosis that utilizes ultra-high frequency signal with data acquisition facility and method " Samsung
Patent documentation 15:JP spy opens 2003-294535 " determinator and the method thereof of the organism temperature of noninvasive " Samsung
Patent documentation 16:JP spy opens 2001-14446 " medical image-processing apparatus " Toshiba and other-individual company
Patent documentation 17:JP spy opens 2004-180932 " device of computer aided diagnosis " Toshiba
Patent documentation 18:JP spy opens 2003-190101 " the organism diagnostic equipment " Konica (コ ニ カ)
Disclosure of an invention
The problem that solves is wanted in invention
As patent documentation 1 as described in the patent documentation 12, known have following such method and apparatus: the irradiation of subtend organism comprises the various electromagnetic waves of light and the signal of seeing through of obtaining, reflection, spontaneous radiation is analyzed, thereby extracts the medically method and apparatus of Useful Information; And, the self power generation magnetic wave of organism is analyzed, thereby extracted the medically method and apparatus of Useful Information.But, obtain Useful Information more, then use the millimere-wave band electromagnetic wave more effective.The invention provides a kind of such method and apparatus, that is, the electromagnetic wave to organism irradiation millimeter wave zone, and to its see through, the signal of reflection, spontaneous radiation analyzes, thereby extracts the medically method and apparatus of Useful Information.
Be used to solve the means of problem
Promptly, the present invention is a kind of display packing of Biont information, have: when preparing first data base in advance (with reference to Fig. 3), prepare second data base (with reference to Fig. 4) in advance, and based on first database information, from shining the operation (with reference to Fig. 5) that electromagnetic wave and reflected electromagnetic wave datum are obtained the virtual condition information of the organism element of checking object that sees through that is measured under the electromagnetic state of millimere-wave band to the organism of checking object, wherein: above-mentioned first data base be from institute's instrumentation under the electromagnetic state of organism irradiation millimere-wave band to see through electromagnetic wave and reflected electromagnetic wave datum, by the virtual condition classification of each organism element and the data base who puts out the millimere-wave band electromagnetic characteristics of organism surface and organism inside in order; Above-mentioned second data base be from do not shine to organism institute's instrumentation under the electromagnetic state to spontaneous radiation electromagnetic wave data, promptly put out the electromagnetic wave spontaneous radiation property database of organism in order by the virtual condition classification of each organism element;
Based on second data base's information, from not shining the operation (with reference to Fig. 6) that the spontaneous radiation electromagnetic wave data that are measured under the electromagnetic state are obtained the virtual condition information of the organism element of checking object to the organism of checking object.In this manual, so-called " virtual condition " is meant states relevant, that institute's instrumentation arrives such as position on the physics with organism, hardness, size.
Fig. 3 is the key diagram of preparing according to the flow process of first database of the millimere-wave band electromagnetic characteristics of the virtual condition classification of each organism inscape and arrangement birth interior of articles; Fig. 4 prepares according to the virtual condition classification of each organism inscape and puts out the key diagram of flow process of second database of the electromagnetic wave spontaneous radiation characteristic of organism in order; Fig. 5 is based on first database information and from shining the key diagram of process flow of virtual condition information that electromagnetic wave and reflection electromagnetic wave data acquisition check the organism inscape of object that sees through that is measured under the electromagnetic state of millimere-wave band to the organism that checks object, and Fig. 6 is based on second database information and from not shining the spontaneous radiation magnetic wave data acquisition that is measured under the electromagnetic state to the organism that checks object and check the key diagram of process flow of virtual condition information of the organism inscape of object.
The millimere-wave band electromagnetic wave is preferably the electromagnetic wave of the electromagnetic wave composition with 6mm to 14mm, more preferably 8mm wavelength (37.5GHz).Preferably, this electromagnetic wave with ultra broadband (UWB:UltraWide Band) electromagnetic wave irradiation on organism.This is because if this is the ultra wide band electrically magnetic wave, then can reduce the energy of each frequency, so the adverse effect that can be avoided the electromagnetic wave of characteristic frequency to bring to organism.The electromagnetic wave energy density that shines organism surface is preferably 40mW/cm 2Below.
The ultra wide band electrically magnetic wave takes place by a plurality of repetition electromagnetic pulses continuous in time.Promptly, preferably, the electromagnetic bandwidth of millimere-wave band of the present invention is more than the 1.5GHz, at least having wavelength is the electromagnetic wave composition of 6mm to 14mm, the millimere-wave band electromagnetic characteristics of organism surface and organism inside is included in ripple at least becomes characteristic in the electromagnetic wave of 6mm to 14mm, millimere-wave band electromagnetic wave of the present invention produces by a plurality of repetition electromagnetic pulses continuous in time, the burst length width of this electromagnetic pulse was 0.1 to 10 nanosecond, and the repetition interval of a plurality of electromagnetic pulses is 0.1 to 10 delicate.
At this, electromagnetic effectiveness with electromagnetic wave composition of 6mm to 14mm has in following three: 1, as first data base's preparation, and irradiation to have see through electromagnetic wave and the reflected electromagnetic wave datum in the resulting optional wavelength of electromagnetic wave zone of the electromagnetic wave composition of 6mm to 14mm be as Biont information and effectively; 2, as second data base's preparation, and do not shine to organism institute's instrumentation under the electromagnetic state to the spontaneous radiation electromagnetic wave data of wavelength region may of 6mm to 14mm be and effectively as Biont information; 3, after irradiation has the electromagnetic wave of electromagnetic wave composition of 6mm to 14mm, postpone on the time and spontaneous radiation occurs, the electromagnetic wave data of the wavelength region may of the 6mm to 14mm of this spontaneous radiation are as Biont information and effectively.
The 3rd, the electromagnetic irradiation with electromagnetic wave composition of 6mm to 14mm becomes blasting fuse (inducement) and causes biological intravital inductive reaction, thereby brings out the spontaneous radiation of the wavelength region may of 6mm to 14mm.Therefore, be included in 1 in a broad sense.In the nature of things, in order to utilize above-mentioned 1 effectiveness, and need to receive the electromagnetic unit of wavelength region may of (specific) arbitrarily.In addition, in the nature of things, in order to utilize above-mentioned 2,3 effectiveness, and need to receive the electromagnetic unit of 6mm to 14mm.
In order to obtain more Biont information, have from different fixed positions to the structure of the electromagnetic a plurality of fixedly radiation sources of organism emission millimere-wave band, as millimere-wave band electromagnetic wave radiation source is loaded in mobile unit mobile the time, from the structure of different positions to the mobile radiation source of organism launching electromagnetic wave and can adopt.Preferably, after all can receiving the information of the relative organism of electromagnetic wave with what kind of position relation (direction and distance) irradiation, arbitrary structure discerns.Therefore, preferably, the positional information of millimere-wave band electromagnetic wave generating source is imbedded (stack) shine to radiation electric wave self.This can realize by electromagnetic encryption technology.Password is decrypted after reception, and obtains having generated the electromagnetic positional information of the electromagnetic irradiation of reception.Preferably, the stack password is the numerical ciphers that obtaining of Biont information do not exerted an influence.As The radar exploration technique and knownly have: the numerical ciphers that on the radiation electric wave, superposes, and carry out password to decipher and the method utilized at receiver side.
Promptly, preferably, the millimere-wave band electromagnetic wave is the position took place an and information that encrypt and be superimposed with this generating means different in different fixed positions or on the time, based on the information of above-mentioned occurrence positions being encrypted and synergetic enciphered method, to shone institute's instrumentation under the electromagnetic state of millimere-wave band to see through electromagnetic wave and the reflected electromagnetic wave datum is decrypted, and resulting millimere-wave band electromagnetic wave occurrence positions information is attached to the millimere-wave band electromagnetic characteristics of organism surface and organism inside.
To take place simultaneously in different fixed positions or different in time position with millimere-wave band electromagnetic wave irradiation that a plurality of timing was taken place at organism and instrumentation arrives sees through electromagnetic wave and reflected electromagnetic wave datum, be transformed to two dimension or three-dimensional organism image information with the technology of known synthetic aperture radar (Synthetic Aperture Radar:SAP).In this image information generates, can utilize available millimere-wave band electromagnetic wave occurrence positions information by above-mentioned password to decipher.
When obtaining the organism image information,, then can improve the treatment effeciency of image transformation if there is the initialize data of the position of biological intravital tissue or internal organs.This position preset preferably the position (position at the acupuncture point of acupuncture) of so-called " through the cave " " meridians " medically to Japan.With these positions as initialize data, and can be used as the tentative position of when determining the position of biological intravital tissue or internal organs, representing the position relation or with these positions as the mesh of image analysis (mesh: focus grid) and utilizing.The meridian-acupoints meridian qi network is not only the three-dimensional relative position coordinates of organism, and is the instrumentation position of being measured Biont information by instrumentation person's health status for understanding.The Biont information value just often of meridian-acupoints meridian qi network is remembered in advance in the data base, and instrumentation is by the Biont information value of the meridian-acupoints meridian qi network of instrumentation person's correspondence, then this normal value and this instrumentation value are compared, and can be with it as being used to understand by instrumentation person's state clue whether normally.For example, suppose that the meridian function of small intestinal is out of balance, and draw the small intestine meridian winding thread by medical diagnosis device of the present invention, then and normal small intestine meridian winding thread between produce difference.If this difference is big more, represent that then the imbalance state is serious more, therefore preferably internal organs corresponding with the small intestinal meridians and histoorgan are carried out the inspection of emphasis.But, if function is normal, then mean institute's instrumentation to flow routes of the meridians and the difference of flow routes of the meridians is little or consistent and do not have condition of illness normally.In addition, in order to solve above-mentioned problem, electromagnetic wave medical diagnosis device of the present invention, it is characterized in that, obtain unit as follows, promptly, this unit possesses two or more analytical methods, this analytical method is at least one of following two kinds of analytical methods, and wherein, a kind of analytical method has the electromagnetic illumination unit and the receiving element in millimeter wave zone; Another kind of analytical method does not have the electromagnetic wave irradiation unit and only is made of the spontaneous electromagnetic unit that receives from as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, and, by having the computer of suitable interface, signal from above-mentioned method of reseptance is synthesized and Flame Image Process, and three dimensional structure, cross-section structure or the surface texture etc. of affected part are carried out pictorial display.In addition, for the electromagnetic wave medical diagnosis device of the present invention that solves above-mentioned problem is characterised in that, obtain unit as follows, promptly, to handle by the digital signal processor class via suitable interface class respectively from the class signal of above-mentioned two or more analytical method, and this class signal imported the digital signal processor class that has storage part and analysis portion and diagnostic software is installed, and synthesize two kinds of signals and implement the analyzing and diagnosing calculation process, the signal that this calculation process result is exported is input to the digital signal processor class and implements processing such as Flame Image Process then, then to outputs such as image display devices and show.
The effect of invention
Obtain the resulting Biont information of method by the Biont information that has used electromagnetic wave zone in the past relatively, by using the millimere-wave band electromagnetic wave, and obtain matter, measure all excellent more, effective Biont information, thereby can carry out more appropriate medical diagnosis with high efficiency.In addition, has following effect: provide a kind of high-resolution, radiationless line loss to hinder, can carry out the diagnostic imaging method and the device of diagnosis at a high speed, and can realize cheap diagnostic fees.In addition, if with the situation that the present invention is used for cancerous diagnose is example, then can utilize diagnosis that tinting of 3-D view diagnosis, profile image diagnosis and affected part show etc. etc. reliably, and therefore affected part that can the early discovery initial stage has and can realize easy effect for the treatment of with high-resolution.The key diagram that is provided for the Biont information of doctor's diagnosis by device of the present invention shown in Figure 7.
The simple declaration of accompanying drawing
Fig. 1 is the key diagram that has adopted with the deriving means (identical with the display device of ultrasound wave CT faultage image) of the Biont information of the present invention of the electromagnetic wave transmitter unit of organism surface contact and receiving element.
Fig. 2 is the key diagram that has adopted with the deriving means (identical with the display device of X ray CT faultage image) of the Biont information of the present invention of discontiguous electromagnetic wave transmitter unit of organism surface and receiving element.
Fig. 3 is the key diagram of preparing according to first data base's of the millimere-wave band electromagnetic characteristics of the virtual condition classification of each organism element and arrangement birth interior of articles flow process.
Fig. 4 prepares according to the virtual condition classification of each organism element and puts out key diagram to second data base's of the electromagnetic wave spontaneous radiation characteristic of organism flow process in order.
Fig. 5 is based on first database information and from shining the key diagram of process flow that electromagnetic wave and reflected electromagnetic wave datum are obtained the virtual condition information of the organism element of checking object that sees through that is measured under the electromagnetic state of millimere-wave band to the organism of checking object.
Fig. 6 is based on second database information and from do not shining the key diagram of process flow that the spontaneous radiation electromagnetic wave data that are measured under the electromagnetic state are obtained the virtual condition information of the organism element of checking object to the organism of checking object.
Fig. 7 is the key diagram that is provided for the Biont information of diagnosis by apparatus of the present invention.
Fig. 8 is the key diagram about electromagnetic ciphering unit of millimere-wave band and decrypting device thereof.
Fig. 9 is the figure about the structure example of millimere-wave band electromagnetic wave transmitter unit.
Figure 10 is the figure about the structure example of electromagnetic wave receiving element.
Figure 11 is the block diagram of wanting portion of an example of the expression radar therapeutic diagnostic equipment of the present invention.
Figure 12 is a block diagram of wanting portion that is suitable for example of expression radar therapeutic method of diagnosis of the present invention and device.
Figure 13 is the flow chart that makes stereo-picture.
Figure 14 is the flow chart that makes of two kinds of stereo-pictures.
Figure 15 is the comparison for MB method and MC method computing required time.
Figure 16 is the block diagram about the DMC method.
Figure 17 is the block diagram about the VOMI system.
Figure 18 is that expression utilizes the radar therapeutic diagnostic equipment of the present invention to come the human body of an example of display gray scale 3-D view to want the sketch map of portion.
The explanation of Reference numeral
D1: with the electromagnetic wave receiving element (identical) of the mode of organism surface contact with the display device of ultrasound wave CT faultage image
D2: with the discontiguous electromagnetic wave receiving element of organism surface (identical) with the display device of X ray CT faultage image
M: the organism of stowage survey object, and the unit that straight line moves in the examination scope of D2
P: the organism of checking object
Rad: the electromagnetic transmitter unit of millimere-wave band (transmitting antenna)
Rec: the millimere-wave band electromagnetic wave is at electromagnetic receiving element or the electromagnetic receiving element of organism spontaneous radiation (reception antenna) of checking that organism is reflected and sees through
DSP: digital signal processor
101: analytic unit portion with electromagnetic wave irradiation unit and receiving element
102: do not have the electromagnetic wave irradiation unit and only by receiving the analytic unit portion that constitutes from spontaneous electromagnetic unit as the bio-tissue of a corpse or other object for laboratory examination and chemical testing
103: image processing part
201: diagnostic bed
202: human body
203: receiving element
204: the scanning direction
301: data acquisition portion
302: resampling portion
303: cut apart/division
304: polygon portion (transformation component and solid are drawn portion)
305: polygon portion (surface extraction portion and transformation component)
306: display part
501: mastery routine (master)
502: secondary program (slave)
601: data acquisition portion
602: data processing division
603: the visual field transformation component
604: electromagnetic beam tracking portion
605: the body unit Projection Division
606: the visual field transformation component
607: display part
701: stereoscopic image data
702: the median surface display part
703: digital stereoscopic image portion
801: data acquisition portion
802: data processing division
803: the data base
804: pre-treatment portion
805: the point of observation transformation component
806: section (slice) makes portion
807: the face image makes portion
808: volume image makes portion
809: display part
810: human computer conversation (interactive) portion
811: image transformation portion
The best mode that is used to carry out an invention
Implement best mode of the present invention as being used to, and device of the present invention is described.Device of the present invention is made of electromagnetic pulse generator, wave frequency adjustor, electromagnetic wave receiver, signal processor etc., but these can be realized by the combination of known technology.As receptor, can use the electromagnetic wave receiver (moisture recorder) in acoustic receiver, optical receiver and infrared ray (temperature) zone etc. as required.
In addition, in the present invention, first, second data base's physical data value is used as color and deep or light information, and to CT (Computer Tomography: same organism faultage image or the three-dimensional stereo-picture demonstration of recombinating computer tomography), but this also can easily realize by known software, image display device.In order to hold complicated organism internal information, also preferred demonstration side by side is as the faultage image or the three-dimensional stereo-picture of the organism of object, but this also can easily realize by known technology.
About constituting hardware of the present invention (electromagnetic wave generator and electromagnetic wave receiver), can consider two kinds of implementation methods (implementations).A kind of is the mode that electromagnetic wave (sound wave) generator and receptor and organism surface are directly contacted, another kind is as X ray CT (Computer Tomography: electromagnetic wave (X ray) generator and receptor are separated from organism, for example surrounded organism with ring-type and be configured.Fig. 1 represents the former, and Fig. 2 represents the latter.
In Fig. 1 and Fig. 2, D1 is the electromagnetic wave receiving element (identical with the display device of ultrasound wave CT faultage image) with the mode of organism surface contact, D2 is and the discontiguous electromagnetic wave receiving element of organism surface (identical with the display device of X ray CT faultage image), M is the organism of stowage survey object, and the unit that straight line moves in the examination scope of D2, P is an organism of checking object, Rad is electromagnetic active transmitter unit, and Rec is the electromagnetic reflection of being launched by Red and sees through electromagnetic detecting unit, perhaps do not shining the electromagnetic detecting unit of spontaneous radiation that institute's instrumentation arrives under the electromagnetic state of millimere-wave band to organism.Rec represents the two, promptly reflects the both sides that reach through electromagnetic active detecting unit and the electromagnetic passive detecting unit of spontaneous radiation, in order to simplify, they is separately illustrated.
The D2 of Fig. 2 is configured in the entire circumference of 360 degree with ring-type, still, also it can be configured in the part, and so that this configuration section measure around the method for the central shaft rotation of ring.This technology is at CT (Computer Tomography: also be known in the technology computer tomography), it easily can be realized based on this.
First, second data base of the present invention is the general data base who is made of common Computer Memory Unit etc., rather than special data base.In data base's making, not only to consider the intensity of electromagnetic wave seeing through in vivo, reflection, spontaneous radiation signal, also preferably carry out data compilation, and can utilize common known signal treatment technology, data base to construct technology at time domain (frequency domain), phase field.
If apparatus structure is summarized record, then for having following Biont information deriving means: first data base, its from organism has been shone institute's instrumentation under the electromagnetic state of millimere-wave band to see through electromagnetic wave and reflected electromagnetic wave datum, classify according to the various virtual conditions of organism element and put out the millimere-wave band electromagnetic characteristics of organism surface and organism inside in order; Second data base, its from organism is not shone institute's instrumentation under the electromagnetic state to spontaneous radiation electromagnetic wave data, the electromagnetic wave spontaneous radiation characteristic of classifying and putting out organism in order according to the various virtual conditions of organism element; Millimere-wave band electromagnetic wave transmitter unit, it is to the organism emission millimere-wave band electromagnetic wave of checking object; First receiving element, it receives electromagnetic wave from the organism that has shone the electromagnetic inspection object of this millimere-wave band; Second receiving element, it receives spontaneous radiating electromagnetic wave from the organism of checking object; Based on the data and above-mentioned first data base and second database information that are obtained by above-mentioned first receiving element and second receiving element, and obtain checking the unit of virtual condition information of the organism element of object.(here, millimere-wave band electromagnetic wave transmitter unit is the Rad among Fig. 1, Fig. 2; First receiving element and second receiving element are not separate illustrated Rec in Fig. 1, Fig. 2.)
Millimere-wave band electromagnetic wave transmitter unit has the radiation source of launching electromagnetic wave, this electromagnetic wave has the electromagnetic wave composition that wavelength is 6mm to 14mm at least, first receiving element has the electromagnetic receptor of reception, and this electromagnetic wave has the electromagnetic wave composition that wavelength is 6mm to 14mm at least.In addition, here, radiation source possesses electromagnetic pulse generator, successive a plurality of repetition electromagnetic pulses on this electromagnetic pulse generator time of origin, and the burst length width of this electromagnetic pulse was 0.1 to 10 nanosecond, and the repetition interval of a plurality of electromagnetic pulses is 0.1 to 10 microsecond.The structure example of these transmitter units of expression and receiving element in Fig. 9 and Figure 10." programmable time-delay regulator " among Fig. 9 and Figure 10 relates to following illustrated encryption.Omit the explanation of square frame among other the figure.
As shown in Figure 1 and Figure 2, millimere-wave band electromagnetic wave transmitter unit by from different fixed positions under the situation that the electromagnetic a plurality of fixedly radiation sources of organism emission millimere-wave band constitute, it has the electromagnetic wave ciphering unit simultaneously, this electromagnetic wave ciphering unit is encrypted and is superimposed upon on the electromagnetic wave that above-mentioned radiation source launches the fixed position information of radiation source, and, first receiving element has the password to decipher unit simultaneously, this password to decipher unit is decrypted receiving the electromagnetic wave data according to the said fixing positional information is encrypted and synergetic enciphered method.So, after the information that the relative organism of reception millimere-wave band electromagnetic wave with what kind of position relation (direction and distance) has carried out shining it is discerned, this helps the assurance to Biont information.More particularly, about to the determining of the position of intravital tissue of biology or internal organs, to the judgement of the state of intravital tissue of biology or internal organs, shine electromagnetic direction and distance can become important condition.
If millimere-wave band electromagnetic wave transmitter unit is to be loaded in mobile unit and mobile the time, from diverse location the mobile radiation source that the millimere-wave band electromagnetic wave is transmitted into organism (is omitted and illustrates: claim 9), then it has the electromagnetic wave ciphering unit simultaneously, this electromagnetic wave ciphering unit is encrypted and is superimposed upon on the electromagnetic wave that above-mentioned mobile radiation source launches the positional information in when emission, and, first receiving element has the password to decipher unit simultaneously, this password to decipher unit information according to above-mentioned launching electromagnetic wave the time is encrypted and synergetic enciphered method, is decrypted receiving the electromagnetic wave data.With above-mentioned same, after the information that the relative organism of reception millimere-wave band electromagnetic wave with what kind of position relation (direction and distance) has carried out shining, it to be discerned, this helps the assurance to Biont information.Fig. 8 is the key diagram about electromagnetic ciphering unit of millimere-wave band and decrypting device thereof.Omission is to the explanation of block diagram among the figure of Fig. 8.
Below, the electromagnetic wave medical diagnosis device at embodiment of the present invention is elaborated based on accompanying drawing.
Figure 11 is the block diagram of wanting portion of an example of expression electromagnetic wave medical diagnosis device of the present invention.
Above-mentioned medical diagnosis device is made up of three parts of analytic unit portion 101, analytic unit portion 102, image processing part 103, and wherein: analytic unit portion 101 has electromagnetic illumination unit and receiving element; Analytic unit 102 does not have the electromagnetic wave irradiation unit and only is made of the spontaneous electromagnetic unit that receives from as the bio-tissue of a corpse or other object for laboratory examination and chemical testing; 103 pairs of signals from the analytic unit of these two systems of image processing part synthesize and analyzing and diagnosing and generate picture signal.
In having the analytic unit portion 101 of electromagnetic illumination unit and receiving element, to handle utilizing amplifier to zoom in about 32 the small-scale digital signal processor (DSP) of suitable digital signal from the signal of synthetic aperture radar, send to image processing part 103 then, wherein, lower powered variable frequency oscillating portion and the antenna part of synthetic aperture radar about by 10~20mW constitutes.
One of the method that is used as the analytic unit with electromagnetic illumination unit and receiving element and device can be enumerated synthetic aperture radar.Synthetic aperture radar is to have used the radar of the technology of phased array antennas (phased array antenna).
In phased array antennas, use the antenna of a plurality of microwave remote sensors in groups.Be provided with phaser at each antenna, and, by the phase place that staggers separately interimly, and with phased array antennas as an antenna sets, so that the mode that a bit (direction and the distance) of focus and the electric wave that is focused overlaps is set.Since electric wave in phase place, be that the point of focus unanimity strengthens, so can measure with the directivity (directionality) and the high resolution of sensitivity.Synthetic aperture radar is a kind of radar as follows, that is, based on phased array antennas, and for example on meteorological satellite the time, get the number of winning the confidence according to moving of satellite continuously with wire, and by date processing it is transformed to the radar of planar instrumentation.
Synthetic aperture radar is the resolution that obtains bigbore relatively radar by little sensor groups, therefore can access high resolution, on the other hand, the Signal Processing that is received need be carried out huge amount of calculation, therefore the property development at computer is utilized very actively to high-caliber in recent years, and mainly is loaded on meteorological satellite and the military aircraft.
Utilize the high-resolution of synthetic aperture radar in the present invention, and can early discovery count the pathological changes at the initial stage of the subject about μ m to 1mm.
Second receiving element as this example, and do not have the electromagnetic wave irradiation unit and only by receiving in the analytic unit portion 102 that constitutes from spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, utilize the small-scale digital signal processor (DSP) about 32 that the signal from receiving element is handled in this example, and implement the removal of various noises, in the time of signal processing such as the smoothing of signal, dwindle data size and make suitable digital signal, and send to image processing part 103, wherein, above-mentioned receiving element is by comprising reception from the lens combination of the infrared radiation of subject, plural infrared ray sensor group portion constitutes.
In image processing part 103, to synthesize from the signal of analytic unit 101 with from packed into about 256 large-scale digital signal processor (DSP) of the diagnostic software that comprises storage part and analysis portion of the signal utilization of subdivision 102, and to implement the calculation process of analyzing and diagnosing at a high speed, the signal that to implement this calculation process then utilizes the digital signal processor (DSP) of the middle scale about 64 to implement Flame Image Process, and this Flame Image Process signal outputed to image display, wherein: above-mentioned analytic unit portion 101 has electromagnetic illumination unit and receiving element; Above-mentioned analytic unit portion 102 does not have the electromagnetic wave irradiation unit and only is made of the spontaneous electromagnetic unit that receives from as the bio-tissue of a corpse or other object for laboratory examination and chemical testing.
By large, medium and small and be expressed as 256,64,32, still, this scale only is for example with the scale of digital signal processor (DSP), and the qualification that is not in the present invention to be done.
In the present invention, the constructional pathological changes with the tissue that detects the patient is the receiving element that purpose utilization has electromagnetic illumination unit.
As not having the electromagnetic wave irradiation unit and, also having the application of infrared ray sensor only by receiving from as one of unitary example of spontaneous electromagnetic unit component analysis of the bio-tissue of a corpse or other object for laboratory examination and chemical testing.The principle origin of this receiving element is in the viewpoint of Japan's medical science, and it is by measuring the Temperature Distribution of body surface, detects the position of the focus that also comprises from the degree of depth of body surface.
In Japan medically, can carry out following judgement: for example, if the rising of the temperature of lip, the then environment that is easy to grow up for tumor; If the temperature of umbilicus descends, then be unfavorable for recovery etc. after being ill.On the mensuration of shell temperature, utilize infrared ray sensor etc.
For the part of the method for utilizing infrared ray sensor, following viewpoint is arranged.Measure heat radiation with infrared ray sensor, thereby obtain the temperature profile of body surface from body surface.The degree of depth of thermal source, promptly be based on such supposition, that is, Gauss distribution can be used in the modelling of the Temperature Distribution of body surface from the inferring of the abnormal portion bit position of the bio-tissue of body surface.Half value point is exactly will be by the binary point of the area that Gaussian distribution curve is surrounded.If can find the half value point, then just can find the degree of depth of thermal source.Carry out aforesaid hypothesis exactly.
In the present invention, by not having the electromagnetic wave irradiation unit and only using one or two above infrared ray sensors by receiving the analytic unit that constitutes from spontaneous electromagnetic unit as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, and the position that can more correctly hold objects such as affected part.
Even utilized an infrared ray sensor, also can infer the degree of depth of the abnormal portion of bio-tissue.But, detect the position of thermal source by infrared ray sensor with different angles, and can more correctly determine the position of thermal source by a plurality of these receiving elements.
In method of the present invention or device, use so-called analytic unit portion with electromagnetic illumination unit and receiving element and do not have the electromagnetic wave irradiation unit and only by the analytic unit that receives multiple modes analytic unit, that principle is different that constitute from spontaneous electromagnetic unit as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, detect the different pathological changes of affected part, and this testing result carried out computing and it is realized various visual anglesization, thereby can more correctly diagnose out affected part.
Figure 12 is a sketch map of wanting portion that is suitable for example of expression electromagnetic wave medical diagnosis device of the present invention.
Diagnostic bed 201 is provided with the human body 202 as an example of subject, and receiving elements such as synthetic aperture radar 203 scan in scanning direction, human body upper edge 104.Here, so-called receiving element is for the receiving element with electromagnetic illumination unit and does not have the electromagnetic wave irradiation unit and only by the general name that receives the method that constitutes from the spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing.
Diagnostic bed 201 size is wide for about 2m length * 80cmm, and is set in the screened room of shielding from the noise class of the electromagnetic wave noise of external environment condition etc. or noise etc.Be provided with the reflecting plate of reflection electromagnetic wave at diagnostic bed 201.
Be set at human body 202 corpse or other object for laboratory examination and chemical testing such as organism such as grade on the diagnostic bed 201, should put on the patient's clothes that constitute by synthetic fibers such as the acrylon that electromagnetic wave or infrared ray are seen through and polyester or nylon etc.
The scan method of receiving element 203 has two kinds of methods, a kind ofly is that human body 202 is static and method that receiving element moves, and another kind is that receiving element 203 is static and method that diagnostic bed 201 and human body 202 move.
The stereoscopic image data that is read in is shown as transparent image as an example.The explicit representation of transparent image for example has maximum echo ripple method, minimum echo method, x-ray method etc.Draw out three dimensional structure, cross-section structure, surface texture, crown structure etc.
Maximum echo ripple method is passed through to show the big position of echo, thereby can be detected for example such pathological changes of hepatic haemangioma.Minimum echo method can detect the pathological changes at the little position of cyst tumor equal echo ripple.X-ray method is a kind of explicit representation similar with the figure of X-ray examination, and its average gray with the result of maximum echo method and minimum echo method is illustrated.
Fig. 7 carries out visual flow chart to the signal of being got by receiving element, mainly illustrates in greater detail 103 parts of Figure 11.Be indicated on the part of this figure with diagnostic bed 201 pairing parts shown in Figure 12.
It is used for from as the internal extraction of the bio-tissue of the human body of determination object etc. and the method for drawing the image of the affected part that becomes object or organism internal organs etc. for a kind of.By the setting suitable threshold, and judge determination objects such as affected part or organism internal organs.
Receive the signal of being got from receiving element 203 by data acquisition portion 301, and carry out following processing: remove noise at 302 pairs of these signals of resampling portion; With the different-format unification of two receiving elements is with a kind of image file format; The volume elements of unified two receiving elements (is also referred to as voxel: size voxel); And the space coordinates of unified volume elements etc.Cutting apart/division 303 in, signal allocation is arrived other system, and, utilize the processing of three-dimensional handling part 304 a side for determination objects such as affected part or organism internal organs, and utilize the processing of polygonization handling part 305, thereby display shape the opposing party.It is a kind of method of drawing out internal structure at three-dimensional the handling part 304 just like transparent human body of equally observing determination object etc.In polygonization handling part 305, draw out the shape of affected part or organism internal organs etc. by the volume elements of drawing a threshold value.Pictorial display processed in three-dimensional handling part 304 and polygonization handling part 305 is at display part 306.
Figure 13 is the flow chart that is used to make stereo-picture.Data from receiving element 203 are read into data acquisition portion 601.And then these data are admitted to amplifies the data processing division of handling with noise remove etc. 602 to signal.Then, will be in visual field transformation component 603 initial data that is read in be carried out to the conversion of the value of the volume elements of solid space, the conversion of coordinate system, conversion of screen coordinate system etc.
In electromagnetic beam tracking portion 604, utilize the processing of electromagnetic beam tracing.In the electromagnetic beam tracing, suppose from the each point launching electromagnetic wave bundle (Beam) of point of observation, and obtain the colour and the opacity of the point on this electromagnetic beam to determination object, and, principle based on " investigation can be seen what color where at this point, and it is all added up ".
The body unit sciagraphy is a kind of colour and opacity method of obtaining spatial shape by obtaining each volume elements.In body unit Projection Division 605, calculate the transparency of the each point that will draw on this contour surface and the gradient of colour (RGB) and inclination etc., and according to material calculate bright dipping diffusion, reflection, see through, absorption, scattering etc. the gloss model, thereby make the stereo-picture of curved surface.
In visual field transformation component 606, according to the angle of looking into the distance determination objects such as affected part or organism internal organs, amplify the multiplying power dwindle or the setting of threshold value, specify and to detect which affected part etc.In display part 607, show the stereo-picture of being drawn.
Figure 14 is the figure of two kinds of manufacture methods of narration solid figure.A kind of method is called the face image making, and it is exactly the method for narrating at Fig. 4.Use threshold value or extreme value to extract contour surface from former stereoscopic image data 701, and will be called median surface by the formed image of contour surface, and, median surface display part 702 is carried out reflection of light, calculating such as sees through as narrating at Fig. 4, thereby make the surface chart picture, and be presented at digital stereoscopic image portion 703.
The face image making is suitable for the mensuration of volume, area, length about object etc.The computing of face image making is light to the burden of hardware, is main flow at present therefore.
Volume image is made not to be needed to constitute median surface from former stereoscopic image data 701, and directly draws.Image is the non-bianry image with gray scale, by drawing translucent structure, and image appearance can be got reality, more directly perceived more.This method for receiving much concern in recent years.
Embodiment 1
Below, to the radar therapeutic diagnostic equipment of the present invention, record and narrate other embodiment among Figure 11 and Figure 12 in detail.
The electromagnetic wave of electromagnetic wave irradiation device with analytic unit of electromagnetic illumination unit and receiving element, be a kind of institute irradiated electromagnetic wave persistent period for from 0.1 nanosecond nanosecond to 10 and interpulse be 100 times to 10000 times the pulse electromagnetic wave in this pulse duration at interval, and be a kind of electromagnetic wave of the single wavelength from 6mm to 12mm wavelength region may.The receiving sensor of this radar is the antenna sets of microwave remote sensor, and with the power of institute's irradiated electromagnetic wave emitters such as wavelength variable microwave, for it is controlled at a corpse or other object for laboratory examination and chemical testing there is not effect so that alleviate burden to an organism corpse or other object for laboratory examination and chemical testing, and below being set at about 10kW, and, when a whole corpse or other object for laboratory examination and chemical testing is scanned, the electromagnetic wave about irradiation 10mW, and when only affected part being scanned, the electromagnetic wave about irradiation 20mW.
Be 10~30 seconds short time the sweep time a when corpse or other object for laboratory examination and chemical testing is human body.Especially mark off affected part and when scanning, only spend the short time about 10 seconds just to finish.Because detection ripple in having the receiving element of this electromagnetic illumination unit is a small-signal, so amplify and send to elementary digital signal processor (DSP) by amplifier.
Do not have the electromagnetic wave irradiation unit and, can also receive self power generation magnetic wave from the micropower of organism only by receiving the analytic unit that constitutes from spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing.
As not having the electromagnetic wave irradiation unit and only by an example that receives the method that constitutes from spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, and be utilized do not have the infrared ray radiation unit and only by as receiving the analytic unit that constitutes from spontaneous electromagnetic unit as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, be a kind ofly to detect from infrared ray that a corpse or other object for laboratory examination and chemical testing took place such as human body or far infrared, do not have the electromagnetic wave irradiation unit and only by receiving the analytic unit that constitutes from spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, and, utilize electromagnetic wave irradiation unit such as not having this infrared ray and, detect the unusual position and the phenomenon of bio-tissue with heat only by receiving the method that constitutes from spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing.Owing to do not have the electromagnetic wave irradiation unit of infrared ray etc. and only big, handle and control so dwindle at primary signal processor (DSP) by the semaphore that receives the analytic unit that constitutes from spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing.
Large-scale digital signal processor (DSP) is a kind of to from the analytic unit with electromagnetic illumination unit and receiving element with do not have the electromagnetic wave irradiation unit and only analyzed and center synthetic, Flame Image Process by the signal that receives the analytic unit that constitutes from the spontaneous electromagnetic receiving element as the bio-tissue of a corpse or other object for laboratory examination and chemical testing, carry out calculation process by Flame Image Process with chip and software, judge position and phenomenon can utilize image and signal.
In the digital signal processor (DSP) of middle scale, be used for the signal from large-scale digital signal processor (DSP) is carried out the processing of image output.
In order to detect the dynamic position in the corpse or other object for laboratory examination and chemical testing, and detect motion with the mensuration of Doppler effect.The dynamically vermicular movement of intentionally dirty, the blood vessel in position, blood flow or the intestines and stomach etc.
As the one example,, and can detect the new life of the blood vessel of the obturation of following internal organs and tumor by the inflow of assessment to the blood of internal organs.
Can form and the position that new vessels is applied to judge tumor will be detected.
The abnormal portion of a corpse or other object for laboratory examination and chemical testing (affected part) is to realize that the method for various visual anglesization detects to use plural pick off.
The performance of composograph has the performance that can tint and show abnormal portion.
For example adopt for fear of interference solid higher-order of oscillation pipe and with 1 the degree the angle of departure, 5 * 5m 2Scope carry out under the situation of the irradiation of multi radiation sources (for example 3 radiation sources), the resolution of composograph is 0.05 * 0.05m 2High-resolution.
As mentioned above, this mode is a high-resolution, thus can find precancer, and (for example no matter be enteral wall or intestinal outer wall) can both determine the position of affected part in all positions of a corpse or other object for laboratory examination and chemical testing.
Embodiment 2
Figure 15 is that the various computational methods of extraction that expression will be carried out contour surface are tried out the example in the processing time when various determination object.The MC method is Marching Cube (mobile cube) method, is a kind of computational methods of allusion.This is to find out the identical volume elements of brightness of volume elements in a kind of adjacent volume elements and the method for shape of drawing out the contour surface of determination object.
Computing is simple in structure, and but then, it is huge that operand becomes, and require computer to have high performance.
The MB method is a Marching Boxes method, be a kind of computational methods as follows, promptly, with the volume segmentation of former stereo data is little unit cube group, and successively and the unit cube that brightness equates in the other unit cube adjacent with unit cube merge, thereby the computational methods of drawing contour surface.
The OctreeMB method is a kind of computational methods that are used for carrying out at high speed the detection of contour surface, and it is with Octree (Octree) performance original digital image data.
Operation time can be shortened, and the high speed of processing can be realized.
Figure 15 represents that with A, B, C be the operation time that object has been used MB method, MC method, OctreeMB method respectively.Compare with the MC method, the face limit number with polygon (being also referred to as polygon (polygon)) in MB method and OctreeMB method is cut to 40% rank.About operation time, concerning all determination objects, the MB method all more spends operation time than MC method mutually, and, if adopt the OctreeMB method, then operation time can be shortened to the degree identical with the MC method.
Embodiment 3
Figure 16 be expression the inventor implemented, on UNIX (registered trade mark) network that has connected computers such as Sun Sparcl the block diagram of the structure of constructed computing method, be called DMC method (DistributedMarching Cubes (disperseing mobile cube) method).
Program is divided into mastery routine side 501 and secondary program side 502, and, in mastery routine side 501, carry out user interface, data collection and data decomposition etc., the calculating of carrying out contour surface in secondary program side 502, and the result offered the mastery routine side.
Mastery routine 501 is determined the quantity of the secondary program 502 that will use according to the scale of data.Secondary program 502 is carried out MC method and Phong model, and result is offered mastery routine 501.Mastery routine 501 usefulness z-buffer methods are implemented hidden surface and are eliminated, and show at the display epigraph.
Adopt the MC method in the extraction computing method of contour surface in the present embodiment, adopt the simply Phong model of gloss model of conduct at the gloss model, the hidden surface of the method that shows becoming the part of the spatial back as cancellation on picture adopts the z-buffer method in eliminating.In addition, in Figure 16, secondary program number is made as three of secondary program 502-1, secondary program 502-2, secondary program 502-3.Above computing method only is an illustration, and the qualification that is not in invention to be done.
The Phong model is characterised in that, uses three characteristics of scattering diffusion, direct reflection, ambient lighting, makes having by the hi-lite of illumination and level and smooth curved surface.The z-buffer method is a kind of method of each pixel memory being wanted the Z value (from the depth of point of observation) of the face that shows.Each face is projected on the perspective projection face, and the shared location of pixels of this face is stored the Z value of this face.At this moment, if there be stored, then compare, and store the information of a little side's face with this Z value.
Embodiment 4
Figure 17 is the example about the flow chart of medical image visual (visualization of medical imaging).Be called the VOMI system.
Initial data from the radar class is read into data acquisition portion 801.These data are saved to data base 803 by data processing division 802 or are read out from data base 803.
Data base 803 is hard disk, floppy disc, CD-R, photomagneto disk, extensive capacity storage devices of computer.
These data enter into pre-treatment portion 804, and implement processing such as noise remove.Carry out the setting at position etc. for the section of the angle of wanting the object of observation or object by point of observation transformation component 805.
Point of observation can be changed by user input apparatus such as mouse, keyboards, and demonstration can be indicated from various angles.
Then, be divided into three operations as required.Can select one or two above operations as required.
Make in the portion 806 in section, draw the calculating of the section of wanting the position observed of object.Make the section of arbitrary plane according to three-dimensional data.
Make in the portion 807 at the face image, draw the position of object, for example calculating of three-dimensional shape such as specific internal organs or tumor.Can carry out the volume calculation, statistical analysis, two dimension, three dimensional shapes mensuration at object position etc.
Make portion 808 at volume image, make the calculating of translucent stereo-picture with gray scale.
At display part 809, the pictorial display that will be calculated in 806,807,808 is on display, printer, film etc.
In human computer conversation portion 810, about the angle of the image that shows, amplify the setting of the threshold value of dwindling, be used to draw which internal organs or affected part etc., the user indicates computer.
In image transformation portion 811, come changing image according to the indication that is provided by human computer conversation portion 810.
Embodiment 5
Figure 18 is that expression utilizes the radar therapeutic diagnostic equipment of the present invention to come the human body of an example of display gray scale 3-D view to want the sketch map of portion.
As mentioned above, can solve problem by radar therapeutic diagnostic method of the present invention and device.That is, the employed microwave of the radar therapeutic diagnostic equipment of the present invention, infrared ray, to compare its resolution all high with ultrasound wave echological diagnosis method and device etc., and can both obtain the resolution of a few μ m.
The radar therapeutic diagnostic equipment of the present invention is not owing to use radiation as tomography X method and device (X ray CT) or positron emission Photographic technique and device (PET), so the danger that the radiant energy of organisms such as human body is damaged not.
As described in embodiment 1, the radar therapeutic diagnostic equipment of the present invention is compared with tomography X method and device (X ray CT), Pumping Magnetic Resonance Method and device (MRI), positron emission Photographic technique and device (PET) etc., and Diagnostic Time is short.
The radar therapeutic diagnostic equipment of the present invention does not need the device as such extensive and high price such as the X-ray generator tomography X method and the device (X ray CT), field generator for magnetic as Pumping Magnetic Resonance Method and device (MRI) and gamma-rays checkout gear, and can be only form by simple and small-sized antenna or pick off with as the digital signal processor of circuit, so can make with cheapness.
Utilizability on the industry
The present invention not only can be used in the electromagnetic wave medical diagnosis, and can be used in: for coagulation The non-destruction of soil and the structure such as tunnel and the be full of cracks of material bodies or the state of reinforcing bar etc., organizer etc. is examined Non-broken ring diagnosis on disconnected, the geology, also have for the stratum, in the state, the spy of water vein of pipeline Various non-destruction diagnosis on the treasure trove diagnosis of looking into etc., other physics.

Claims (10)

1. device that obtains and show Biont information is characterized in that having:
From shone to organism institute's instrumentation under the electromagnetic state of millimere-wave band to see through electromagnetic wave and reflected electromagnetic wave datum, by each the organism element classification and first data base that puts out the millimere-wave band electromagnetic characteristics of organism surface and organism inside in order;
From do not shine to organism institute's instrumentation under the electromagnetic state to spontaneous radiation electromagnetic wave data, by the virtual condition classification of each organism element and put out second data base of the electromagnetic wave spontaneous radiation characteristic of organism in order;
Millimere-wave band electromagnetic wave transmitter unit, it is to the organism emission millimere-wave band electromagnetic wave of checking object;
First receiving element, it receives electromagnetic wave from the organism that is irradiated to the electromagnetic inspection object of this millimere-wave band;
Second receiving element, it accepts the electromagnetic wave of spontaneous radiation from the organism of checking object;
The first organism virtual condition information acquisition unit, it obtains the virtual condition information of the organism element of checking object based on by resulting data of above-mentioned first receiving element and above-mentioned first data of database;
The second organism virtual condition information acquisition unit, it obtains the virtual condition information of the organism element of checking object based on by resulting data of second receiving element and above-mentioned second data of database;
Based on first and second data of database and by the resulting information of the first and second organism virtual condition information acquisition unit, show the unit of Biont information.
2. the device that obtains and show Biont information as claimed in claim 1 is characterized in that,
First or second data base comprises and the relevant data of meridian-acupoints meridian qi network preset position information, and this meridian-acupoints meridian qi network preset position information to be representing the position of the meridian-acupoints meridian qi network of organism with the relative far and near relation of organism element,
First or the second organism virtual condition information acquisition unit of obtaining the virtual condition information of the organism element of checking object comprises: from the meridian-acupoints meridian qi network preset position information that is comprised above-mentioned first or second data of database, with shone to the organism of checking object be measured under the electromagnetic state of millimere-wave band see through electromagnetic wave and reflected electromagnetic wave datum, do not shining the spontaneous radiation electromagnetic wave data that are measured under the electromagnetic state of millimere-wave band to the organism of checking object, the unit of the virtual condition position of the meridian-acupoints meridian qi network of the organism of judgement inspection object
The unit of demonstration Biont information comprises the unit of the virtual condition position that shows the meridian-acupoints meridian qi network, and the virtual condition position of this meridian-acupoints meridian qi network is resulting by the unit of the virtual condition position of the meridian-acupoints meridian qi network of the organism of judging above-mentioned inspection object.
3. the device that obtains and show Biont information as claimed in claim 2 is characterized in that,
First or second data of database comprises the relevant data of position range information with just often meridian-acupoints meridian qi network, the position range information of this meridian-acupoints meridian qi network just often is to represent the position range of the meridian-acupoints meridian qi network of organism just often with the relative far and near relation of organism element
First or the second organism virtual condition information acquisition unit of obtaining the virtual condition information of the organism element of checking object comprises: according to by the virtual condition position of the resulting meridian-acupoints meridian qi network in unit of the virtual condition position of the meridian-acupoints meridian qi network of judging the organism of checking object and above-mentioned just often the position range information of meridian-acupoints meridian qi network, judge the unit in normal range whether, position of the meridian-acupoints meridian qi network of the organism of checking object
The unit that shows Biont information comprises the unit that is used to show, this unit that is used to show shows whether the above-mentioned unit of judging is judged to be in normal range.
4. as each described device that obtains and show Biont information in the claim 1 to 3, it is characterized in that,
The electromagnetic bandwidth of the millimere-wave band of being shone is more than the 1.5GHz, and has the electromagnetic wave composition that wavelength is 6mm to 14mm in this frequency band at least,
The electromagnetic wave spontaneous radiation characteristic of the millimere-wave band electromagnetic characteristics of first data base's organism surface and organism inside and/or second data base's organism comprises that at least wavelength is the electromagnetic characteristic of 6mm to 14mm,
Millimere-wave band electromagnetic wave transmitter unit has radiation source, and this radiation source emission has the electromagnetic wave that wavelength is the electromagnetic wave composition of 6mm to 14mm at least,
First receiving element has receptor, and this receptor receives has the electromagnetic wave that wavelength is the electromagnetic wave composition of 6mm to 14mm at least.
5. as each described device that obtains and show Biont information in the claim 1 to 3, it is characterized in that,
The millimere-wave band electromagnetic wave that is shone is to take place by a plurality of repetition electromagnetic pulses continuous in time, and the burst length width of this electromagnetic pulse was 0.1 to 10 nanosecond, and the repetition interval of a plurality of electromagnetic pulses is 0.1 to 10 microsecond.
6. the device that obtains and show Biont information as claimed in claim 5 is characterized in that,
Interpulse period between a plurality of repetition electromagnetic pulses is 100 times to 10000 times of burst length width of this electromagnetic pulse.
7. as each described device that obtains and show Biont information in the claim 1 to 3, it is characterized in that,
The millimere-wave band electromagnetic wave transmitter unit and first receiving element are the transmission receiving elements of synthetic aperture radar, send to receive seeing through or reflection electromagnetic wave of a plurality of phase shiftings, receive and electromagnetic wave by the resulting electromagnetic wave same degree of receiving element that opening degree is big in appearance from the organism of checking object.
8. as each described device that obtains and show Biont information in the claim 1 to 3, it is characterized in that,
Millimere-wave band electromagnetic wave transmitter unit is by constituting from different fixed positions to the electromagnetic a plurality of fixedly radiation sources of organism emission millimere-wave band, and, has the electromagnetic wave ciphering unit simultaneously, this electromagnetic wave ciphering unit is encrypted and is superimposed upon on the electromagnetic wave that above-mentioned radiation source launches the fixed position information of radiation source
First receiving element has the password to decipher unit simultaneously, and this password to decipher unit is decrypted receiving the electromagnetic wave data based on the said fixing positional information being encrypted and synergetic enciphered method.
9. as each described device that obtains and show Biont information in the claim 1 to 3, it is characterized in that,
Millimere-wave band electromagnetic wave transmitter unit be loaded in mobile unit and mobile the time from diverse location to the electromagnetic mobile radiation source of organism emission millimere-wave band, and, has the electromagnetic wave ciphering unit simultaneously, this electromagnetic wave ciphering unit is encrypted and is superimposed upon on the electromagnetic wave that above-mentioned mobile radiation source launches the positional information in when emission
First receiving element has the password to decipher unit simultaneously, and the positional information of this password to decipher unit based on to above-mentioned launching electromagnetic wave the time encrypted and synergetic enciphered method, is decrypted receiving the electromagnetic wave data.
10. the device that obtains and show Biont information as claimed in claim 2 is characterized in that,
The unit of the virtual condition position of above-mentioned demonstration meridian-acupoints meridian qi network comprises:
Will be through the cave as point, with meridians as line, and to the preset position information of meridian-acupoints meridian qi network and institute's instrumentation to the virtual condition positional information of meridian-acupoints meridian qi network construct the unit of three-dimensional data respectively;
This three-dimensional data of naming a person for a particular job according to the observation is converted to the unit that two dimension shows.
CNB2005800232440A 2004-07-09 2005-07-11 Method for acquiring bioinformation using millimeter-wave band electromagnetic wave, device for acquiring and displaying bioinformation Expired - Fee Related CN100459943C (en)

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