CN100411955C - Temperature monitoring method of object during transportation process - Google Patents
Temperature monitoring method of object during transportation process Download PDFInfo
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- CN100411955C CN100411955C CNB200410035477XA CN200410035477A CN100411955C CN 100411955 C CN100411955 C CN 100411955C CN B200410035477X A CNB200410035477X A CN B200410035477XA CN 200410035477 A CN200410035477 A CN 200410035477A CN 100411955 C CN100411955 C CN 100411955C
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Abstract
The present invention relates to a temperature monitoring method for an article in the process of transportation and storage, which orderly comprises the steps that monitoring agents are selected, the monitoring agents are pulverized, the monitoring agents are enclosed, and the monitoring agents and a monitored article are sealed and packed in a transparent packing bag, wherein the monitoring agents are selected according to a limited temperature upper limit value of the monitored article in the process of transportation and storage, and a compound with the melting point less than or equal to the temperature upper limit value is selected. By adopting the temperature monitoring method for an article in the process of transportation and storage of the present invention, whether the temperature of the monitored article in the process of transportation and storage exceeds the limited temperature upper limit value or not can be judged by observing the form of the monitoring agents which are packed with the monitored article to guarantee the quality of the monitored article.
Description
Technical field
The present invention relates to a kind of temperature monitoring method, the temperature monitoring method of a kind of article in the transportation storage process of more specifically saying so.
Background technology
Some product, particularly medicine have strict qualification to temperature in transporting storage process, as hepatitis B vaccine, be limited to 2 ℃-8 ℃ temperature conditions transportation and storage down, and when the temperature of temperature above this qualification, its quality just is difficult to guarantee.At present, about these have the strict product that limits to temperature in transportation and storage process, manufacturer just marks in the specification sheets of product export especially, as for each link in transportation behind the product export and the storage keeping, whether go to carry out, also lack the efficient temperature monitoring means by the requirement of product description.The patent No. is 01262241.9 " a kind of blood hutch ", has just solved the temperature requirement of storing different blood products, has prolonged the preservation haulage time, but is not suitable for the storage transportation to other article.
Summary of the invention
The purpose of this invention is to provide the temperature monitoring method of a kind of article in the transportation storage process.
The temperature monitoring method of the article that provided in the transportation storage process comprises the steps: successively
A, selection monitoring agent, the temperature upper limit of article defined in the transportation storage process that foundation is monitored, select fusing point to be less than or equal to the cmpd of this temperature upper limit, this cmpd is thin agllutination crystal, after temperature becomes melt above fusing point, even temperature drops to again below the fusing point, formed macrocrystalline body can not revert to former thin agllutination crystal yet;
B, pulverize the monitoring agent, the monitoring agent that will select earlier is lower than in temperature that usual manner is dried to and can pulverizes under the condition of its fusing point, is ground into the thin piece that granularity is not more than 2mm again;
C, encapsulation monitoring agent, the monitoring agent that will be ground into thin piece earlier is contained in the vitreous glazing container, again with this glass container sealing;
D, packing, be equipped with monitoring agent and sealed glass container with monitored article sealed package in transparent packaging bag.
The temperature monitoring method of article of the present invention in the transportation storage process, its described article comprise medicine, Food ﹠ Drink.
The temperature monitoring method of above-mentioned article in the transportation storage process, when the monitored temperature upper limit that article limited is 8 ℃, the monitoring agent is a cinnamyl chlorine, when the monitored temperature upper limit that article limited is 11 ℃, the monitoring agent is o-chlorobenzaldehyde or 2-benzyl pyridine, when the monitored temperature upper limit that article limited is 12 ℃, the monitoring agent is an ethyl myristate, when the monitored temperature upper limit that article limited is 20 ℃, the monitoring agent is a sodium chromate, when the monitored temperature upper limit that article limited is 21 ℃, the monitoring agent is 1, the 2-dimethoxy benzene, when the monitored temperature upper limit that article limited was 29 ℃, the monitoring agent was a cyclohexane-carboxylic acid.
In the present invention, the physical property of selected monitoring agent all is a crystlline, is acicular crystals as cinnamyl chlorine, and cyclohexane-carboxylic acid is the prismatic crystlline.Pack with monitored article when it being ground into thin piece, in the transportation storage process, in case temperature surpasses the fusing point of selected monitoring agent, this monitoring agent will be melted, its form changes, and becomes melt, even temperature is reduced to below the fusing point again, what its form presented is the crystlline of bulk, can not return to former thin agllutination crystal.
Learn by top narration, adopt the temperature monitoring method of article of the present invention in the transportation storage process, by observing the form of the monitoring agent of packing with monitored article, just can judge the temperature of monitored article in the transportation storage process and whether surpass the temperature upper limit that is limited, promptly monitor agent and still be thin agllutination crystalline substance, prove that the temperature of monitored article in the transportation storage process do not surpass the temperature upper limit that is limited, the monitoring agent is if become melt, prove that the temperature of monitored article in the transportation storage process surpasses the temperature upper limit that is limited, the monitoring agent is if become the crystlline of bulk, prove that the temperature of monitored article in the transportation storage process once surpassed the temperature upper limit that is limited, and guaranteed article quality.
The specific embodiment
Example 1
When monitored medicine is refined diphtheria antitoxin, refined tetanus antitoxin, human rabies purified vaccine or hepatitis B vaccine, these medicines are 8 ℃ at the temperature upper limit of transportation defined in the storage process, and it is 8 ℃ cinnamyl chlorine that fusing point is selected in the monitoring agent for use.At cinnamyl chlorine below 8 ℃ is acicular crystals, with dryer or vacuum drying apparatus cinnamyl chlorine is being dried to and can pulverizing below 8 ℃, again it is ground into the thin piece that granularity is not more than 2mm, is contained in long 50mm, wall thickness 0.6mm, internal diameter is in the glass tube of 5mm, at last glass tube is sealed.With being housed, the sealed glass tube of cinnamyl chlorine and monitored medicine be packaged together with same transparent plastic bag.If surpass 8 ℃ in transportation certain link temperature in the storage process, cinnamyl chlorine can melt, and form changes and resilient not, realizes the monitoring temperature of said medicine in the transportation storage process by cinnamyl chlorine.
Example 2
When monitored medicine is oxytocin inj, idoxuridine ophthalmic solution, chloramphenicol ophthalmic solution or gentamicine sulphate injection, when the temperature upper limit defined in the transportation storage process is 20 ℃, it is 19.9 ℃ of sodium chromates that are the yellow crystal body that fusing point is selected in the monitoring agent for use, and all the other are with example 1.
Example 3
When monitored article were Foods or drinks, if when the temperature upper limit of transportation defined in the storage process is 29 ℃, it was that 29 ℃, form are the cyclohexane-carboxylic acids of prismatic crystlline that fusing point is selected in the monitoring agent for use, and all the other are with example 1.
Claims (8)
1. the temperature monitoring method of article in the transportation storage process is characterized in that comprising the steps: successively
A, selection monitoring agent, the temperature upper limit of article defined in the transportation storage process that foundation is monitored, select fusing point to be less than or equal to the cmpd of this temperature upper limit, this cmpd is thin agllutination crystal, after temperature becomes melt above fusing point, even temperature drops to again below the fusing point, formed macrocrystalline body can not revert to former thin agllutination crystal yet;
B, pulverize the monitoring agent, the monitoring agent that will select earlier is lower than in temperature that usual manner is dried to and can pulverizes under the condition of its fusing point, is ground into the thin piece that granularity is not more than 2mm again;
C, encapsulation monitoring agent, the monitoring agent that will be ground into thin piece earlier is contained in the vitreous glazing container, again with this glass container sealing;
D, packing, be equipped with monitoring agent and sealed glass container with monitored article sealed package in transparent packaging bag.
2. the temperature monitoring method of article according to claim 1 in the transportation storage process is characterized in that said article comprise medicine, Food ﹠ Drink.
3. the temperature monitoring method of article according to claim 1 in the transportation storage process is characterized in that when the monitored temperature upper limit that article limited is 8 ℃ the monitoring agent is a cinnamyl chlorine.
4. the temperature monitoring method of article according to claim 1 in the transportation storage process is characterized in that when the monitored temperature upper limit that article limited is 11 ℃ the monitoring agent is o-chlorobenzaldehyde or 2-benzyl pyridine.
5. the temperature monitoring method of article according to claim 1 in the transportation storage process is characterized in that when the monitored temperature upper limit that article limited is 12 ℃ the monitoring agent is an ethyl myristate.
6. the temperature monitoring method of article according to claim 1 in the transportation storage process is characterized in that when the monitored temperature upper limit that article limited is 20 ℃ the monitoring agent is a sodium chromate.
7. the temperature monitoring method of article according to claim 1 in the transportation storage process is characterized in that when the monitored temperature upper limit that article limited is 21 ℃ the monitoring agent is 1, the 2-dimethoxy benzene.
8. the temperature monitoring method of article according to claim 1 in the transportation storage process is characterized in that when the monitored temperature upper limit that article limited is 29 ℃ the monitoring agent is a cyclohexane-carboxylic acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200410035477XA CN100411955C (en) | 2004-07-31 | 2004-07-31 | Temperature monitoring method of object during transportation process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200410035477XA CN100411955C (en) | 2004-07-31 | 2004-07-31 | Temperature monitoring method of object during transportation process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1597459A CN1597459A (en) | 2005-03-23 |
| CN100411955C true CN100411955C (en) | 2008-08-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB200410035477XA Expired - Fee Related CN100411955C (en) | 2004-07-31 | 2004-07-31 | Temperature monitoring method of object during transportation process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100411955C (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0563769A1 (en) * | 1992-04-01 | 1993-10-06 | BASF Magnetics GmbH | Temperature indicator for deep-frozen products |
| WO1998038112A1 (en) * | 1997-02-27 | 1998-09-03 | Visual Indicator Tag Systems - Vitsab Ab | Package and method of making the same |
| DE29907082U1 (en) * | 1999-04-21 | 1999-09-09 | Hebben Michael | Clear plastic shell with three recesses for fixing colored frozen liquids |
| US6030118A (en) * | 1995-06-30 | 2000-02-29 | Emtec Magnetics Gmbh | Temperature indicator for refrigerated products or the like |
-
2004
- 2004-07-31 CN CNB200410035477XA patent/CN100411955C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0563769A1 (en) * | 1992-04-01 | 1993-10-06 | BASF Magnetics GmbH | Temperature indicator for deep-frozen products |
| US6030118A (en) * | 1995-06-30 | 2000-02-29 | Emtec Magnetics Gmbh | Temperature indicator for refrigerated products or the like |
| WO1998038112A1 (en) * | 1997-02-27 | 1998-09-03 | Visual Indicator Tag Systems - Vitsab Ab | Package and method of making the same |
| DE29907082U1 (en) * | 1999-04-21 | 1999-09-09 | Hebben Michael | Clear plastic shell with three recesses for fixing colored frozen liquids |
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| Publication number | Publication date |
|---|---|
| CN1597459A (en) | 2005-03-23 |
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Granted publication date: 20080820 Termination date: 20100731 |