CN100404679C - GRF(1-32)and SS-HbsAg fusion gene combination and its constructed expression system and pharmaceutical preparation - Google Patents
GRF(1-32)and SS-HbsAg fusion gene combination and its constructed expression system and pharmaceutical preparation Download PDFInfo
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- CN100404679C CN100404679C CNB2005100171542A CN200510017154A CN100404679C CN 100404679 C CN100404679 C CN 100404679C CN B2005100171542 A CNB2005100171542 A CN B2005100171542A CN 200510017154 A CN200510017154 A CN 200510017154A CN 100404679 C CN100404679 C CN 100404679C
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- grf
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Abstract
Description
Time (d) | Physiological saline | p-GRF | p-HBsAg/SS | p-GRF-HBsAg/SS |
15 | 333.75± 36.84 | 500.00±25.35** | 413.25±29.61* | 528.75±29.69** |
30 | 488.75± 32.92 | 767.50±33.58** | 785.00±69.26** | 848.75±54.95** |
45 | 871.25± 58.23 | 1170.00±38.91** | 1135.00±65.44** | 1221.25±59.00** |
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CNB2005100171542A CN100404679C (en) | 2005-09-23 | 2005-09-23 | GRF(1-32)and SS-HbsAg fusion gene combination and its constructed expression system and pharmaceutical preparation |
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CNB2005100171542A CN100404679C (en) | 2005-09-23 | 2005-09-23 | GRF(1-32)and SS-HbsAg fusion gene combination and its constructed expression system and pharmaceutical preparation |
Publications (2)
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CN1769453A CN1769453A (en) | 2006-05-10 |
CN100404679C true CN100404679C (en) | 2008-07-23 |
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CNB2005100171542A Active CN100404679C (en) | 2005-09-23 | 2005-09-23 | GRF(1-32)and SS-HbsAg fusion gene combination and its constructed expression system and pharmaceutical preparation |
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Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101804209B (en) * | 2010-03-31 | 2012-07-04 | 四川大学 | PEDF (Pigment Epithelial Derived Factor) gene PLGA nano compound as well as preparation method and use thereof |
CN105194662B (en) * | 2015-09-16 | 2018-08-28 | 华北制药金坦生物技术股份有限公司 | Sustained release microsphere agents and preparation method thereof containing recombination hepatitis B surface antigen |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0459747A1 (en) * | 1990-05-29 | 1991-12-04 | Eli Lilly And Company | Precursor forms of porcine growth hormone releasing factor and related DNA compounds |
CN1201831A (en) * | 1997-06-05 | 1998-12-16 | 中国科学院微生物研究所 | Method for preparation of recombined human luteinizing-hormone releasing factor |
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2005
- 2005-09-23 CN CNB2005100171542A patent/CN100404679C/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0459747A1 (en) * | 1990-05-29 | 1991-12-04 | Eli Lilly And Company | Precursor forms of porcine growth hormone releasing factor and related DNA compounds |
CN1201831A (en) * | 1997-06-05 | 1998-12-16 | 中国科学院微生物研究所 | Method for preparation of recombined human luteinizing-hormone releasing factor |
Non-Patent Citations (4)
Title |
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. 动物生理生化第八次学术会议论文摘要汇编. 2004 |
. 动物生理生化第八次学术会议论文摘要汇编. 2004 * |
生长激素释放因子(GRF)的基因改造及化学合成. 冯立文等.中国兽医学报,第18卷第6期. 1998 |
生长激素释放因子(GRF)的基因改造及化学合成. 冯立文等.中国兽医学报,第18卷第6期. 1998 * |
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CN1769453A (en) | 2006-05-10 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Shenzhen agriculture and animal husbandry industry Co., Ltd. Assignor: Zhang Yongliang Contract fulfillment period: 2008.8.25 to 2013.8.25 contract change Contract record no.: 2008440000381 Denomination of invention: GRF (1-32) and SS-HBsAg fusion gene combinations and their expressed expression systems and pharmaceutical formulations Granted publication date: 20080723 License type: Exclusive license Record date: 20081118 |
|
LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.8.25 TO 2013.8.25; CHANGE OF CONTRACT Name of requester: SHENZHEN CITY NONGMU INDUSTRY CO.,LTD. Effective date: 20081118 |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20180129 Address after: 510000 Guangdong province high tech Industrial Development Zone of Guangzhou Science City A804 skim Springs Road No. 3 Guangzhou international business incubator District real A Patentee after: Guangzhou Chuang Xi Wan biological science and Technology Co., Ltd. Address before: 130021 Xinmin Street, Changchun, Changchun, Jilin Province, Jilin University Patentee before: Zhang Yongliang |