CN100372519C - Medicine filling method of levonorgestrel silica gel stick - Google Patents
Medicine filling method of levonorgestrel silica gel stick Download PDFInfo
- Publication number
- CN100372519C CN100372519C CNB2005100456142A CN200510045614A CN100372519C CN 100372519 C CN100372519 C CN 100372519C CN B2005100456142 A CNB2005100456142 A CN B2005100456142A CN 200510045614 A CN200510045614 A CN 200510045614A CN 100372519 C CN100372519 C CN 100372519C
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- China
- Prior art keywords
- pipe
- medicine
- silicone rubber
- rubber tube
- levonorgestrel
- Prior art date
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Abstract
The present invention discloses a method for filling levonorgestral silastic implant medicines. One end of a silicon rubber pipe is folded, and the other end is inserted in a charging funnel. Medicine powder is filled in the silicon rubber pipe by a rod-shaped tool in a mode of delivering the medicine into the pipe with the certain distance away from the pipe end. The present invention is simple and practical, the accuracy of the quantity of the loaded medicine is easily guaranteed, the medicine powder is difficult to flow out in weighing, both of the two ends of the silicon rubber pipe are conveniently plugged as required after being filled, and the productive efficiency and the product yield are high.
Description
Technical field
What the present invention relates to is pharmaceutical processing technology, particularly levonorgestrel silastic rod (I) medicine fill method.
Background technology
Levonorgestrel silastic rod is a kind of medicine to be filled subdermal implants in silicone rubber tube.The free volume of the medicine owing to pack in the silicone rubber tube is greater than the silicone rubber tube volume, common plain mode in the life to pipe inner stuffing material, the accuracy of dose can't guarantee to pack into, and medicated powder flows out easily when weighing, also inconvenience will be filled silicone rubber tube two ends, back peace and be required shutoff, can not satisfy the pharmaceutical processing requirement, influence product yield, can not satisfy the working (machining) efficiency demand.Do not see at present the disclosed filling technique method of this medicine is arranged.
Summary of the invention
The purpose of this invention is to provide a kind of simple and practical medicine filling method of levonorgestrel silica gel stick.
Medicine filling method of levonorgestrel silica gel stick of the present invention is:
(1), an end (about 1/3rd places) of silicone rubber tube is folding, insert the powder charge funnel from the other end, with rod tool medicine is sent in the pipe of certain (about 1/4th places) distance of pipe end, medicine is heaped in pipe naturally, and the outer end place that makes the medicine in the pipe of packing into is the silicone rubber tube stay infraction that rises, and decontrols to fold;
(2), insert the powder charge funnel, with rod tool medicine is sent in the pipe of certain (about 1/4th places) distance of pipe end, medicine is heaped in pipe naturally, and the outer end of the interior medicine of pipe of packing into is located the silicone rubber tube stay infraction that rises from the other end;
(3), weighing detects;
(4), the silicone rubber tube two ends are clean with adherent medicated powder cleaning with instrument greater than the inside pipe wall that seals length;
(5), with the two ends shutoff of silicone rubber with silicone rubber tube;
(6), treat that sealing two ends silicone rubber solidifies after, the silicone rubber rod is rubbed arrangement with flat board restores to the original state, make medicine uniform distribution in silicone rubber tube.
Medicine filling method of levonorgestrel silica gel stick of the present invention is simple and practical, and the accuracy of the dose that guarantees easily to pack into, and medicated powder is not easy to flow out when weighing is convenient to silicone rubber tube two ends, fillings back are pacified requiring shutoff, production efficiency and product yield height
Description of drawings
Fig. 1-the 5th, fill method schematic diagram of the present invention.
The specific embodiment
(1), the about 10mm of the end place of the silicone rubber tube that 34mm is long is folding, insert powder charge funnel (referring to Fig. 1) from the other end, with rod tool medicine is sent in the pipe of the about 8mm of pipe end place distance, and the outer end of the medicine in the pipe of packing into is located, promptly the silicone rubber tube stay risen (referring to Fig. 2) apart from the about 8mm of mouth of pipe place, form infraction, decontrol folding then;
(2), insert the powder charge funnel, with rod tool medicine is sent in the pipe of the about 8mm of pipe end place distance, and risen by the silicone rubber tube stay (referring to Fig. 3) in the place, outer end of the medicine in the pipe of packing into, formation is blocked from the other end,
(3), weighing detects;
(4), the silicone rubber tube two ends are clean with adherent medicated powder cleaning with instrument such as cotton swab greater than the inside pipe wall that seals length 2mm;
(5), with the two ends shutoff (referring to Fig. 4) of silicone rubber with silicone rubber tube;
(6), treat that sealing two ends silicone rubber solidifies after, the silicone rubber rod is rubbed arrangement with flat board restores to the original state, make medicine uniform distribution (referring to Fig. 5) in silicone rubber tube.
Claims (2)
1. medicine filling method of levonorgestrel silica gel stick is characterized in that:
(1), an end of silicone rubber tube is folding, insert the powder charge funnel from the other end, with rod tool medicine is sent in the pipe of pipe end certain distance, medicine is heaped in pipe naturally, and the outer end place that makes the medicine in the pipe of packing into is the silicone rubber tube stay infraction that rises, and decontrols to fold;
(2), insert powder charge funnel from decontroling this end of folding sebific duct again, with rod tool medicine is sent in the pipe of this end pipe end certain distance, medicine is heaped in pipe naturally, and the outer end of the interior medicine of pipe of packing into is located the silicone rubber tube stay infraction that rises;
(3), weighing detects;
(4), silicone rubber tube two ends oral area inside pipe wall is clean with adherent medicated powder cleaning with instrument;
(5), with the two ends shutoff of silicone rubber with silicone rubber tube;
(6), treat that sealing two ends silicone rubber solidifies after, the silicone rubber rod is rubbed arrangement with flat board restores to the original state, make medicine uniform distribution in silicone rubber tube.
2. according to right 1 described medicine filling method of levonorgestrel silica gel stick, it is characterized in that: about 1/3rd places of an end of silicone rubber tube are folding; With rod tool medicine is sent in the pipe of about 1/4th place's distances of pipe end.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100456142A CN100372519C (en) | 2005-01-06 | 2005-01-06 | Medicine filling method of levonorgestrel silica gel stick |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100456142A CN100372519C (en) | 2005-01-06 | 2005-01-06 | Medicine filling method of levonorgestrel silica gel stick |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1799530A CN1799530A (en) | 2006-07-12 |
| CN100372519C true CN100372519C (en) | 2008-03-05 |
Family
ID=36809891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100456142A Expired - Fee Related CN100372519C (en) | 2005-01-06 | 2005-01-06 | Medicine filling method of levonorgestrel silica gel stick |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100372519C (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2090277U (en) * | 1990-05-29 | 1991-12-11 | 中国人民解放军89720部队513医院 | Full-embedded semi-automatic administering apparatus for analgesic |
| CN1295022A (en) * | 1999-09-30 | 2001-05-16 | 钟渊化学工业株式会社 | Powder-filling method and device |
| US20030100806A1 (en) * | 2001-01-23 | 2003-05-29 | Lal Gauri Sankar | Synthesis of vicinal difluoro aromatics and intermediates thereof |
| US20040003866A1 (en) * | 2002-06-27 | 2004-01-08 | Nektar Therapeutics | Apparatus and method for filling a receptacle with powder |
| CN1634077A (en) * | 2004-11-18 | 2005-07-06 | 王立强 | Orally disintegrating tablet of levonogestrel and its preparing process |
-
2005
- 2005-01-06 CN CNB2005100456142A patent/CN100372519C/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2090277U (en) * | 1990-05-29 | 1991-12-11 | 中国人民解放军89720部队513医院 | Full-embedded semi-automatic administering apparatus for analgesic |
| CN1295022A (en) * | 1999-09-30 | 2001-05-16 | 钟渊化学工业株式会社 | Powder-filling method and device |
| US20030100806A1 (en) * | 2001-01-23 | 2003-05-29 | Lal Gauri Sankar | Synthesis of vicinal difluoro aromatics and intermediates thereof |
| US20040003866A1 (en) * | 2002-06-27 | 2004-01-08 | Nektar Therapeutics | Apparatus and method for filling a receptacle with powder |
| CN1634077A (en) * | 2004-11-18 | 2005-07-06 | 王立强 | Orally disintegrating tablet of levonogestrel and its preparing process |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1799530A (en) | 2006-07-12 |
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|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080305 Termination date: 20140106 |