CN100344266C - Vetebrae anterior biological osteogenesis-inducing type internal fixing device - Google Patents

Vetebrae anterior biological osteogenesis-inducing type internal fixing device Download PDF

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Publication number
CN100344266C
CN100344266C CNB2004100034273A CN200410003427A CN100344266C CN 100344266 C CN100344266 C CN 100344266C CN B2004100034273 A CNB2004100034273 A CN B2004100034273A CN 200410003427 A CN200410003427 A CN 200410003427A CN 100344266 C CN100344266 C CN 100344266C
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hole
fixing head
trough
fixing device
type inner
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CNB2004100034273A
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CN1663538A (en
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王岩
白一冰
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Abstract

The present invention relates to a vertebrae anterior biological osteogenesis inducting type inner fixing device which comprises a fixing plate and a fixing hole arranged on the fixing plate, wherein the bottom of the fixing plate is also provided with at least one bone preplacing groove which is used for implanting autogenous or variant bones or other artificial bones and is projected out of the fixing plate, four or more than four fixing holes are evenly distributed on the periphery of the fixing plate, and the fixing hole is a sloping hole or a positive thread hole or a sloping thread hole or a T-shaped hole or a reverse trapezoidal hole. The fixing plate has a longitudinal arc degree which is similar to the physiological curvature angle of the vertebra. The autogenous bones or the variant bones or other artificial bones can be placed into the preplacing bone groove in advance in an operation, the regeneration effect is induced by the interface of the fixing plate or is guided by bones, and simulative fixed adjacent vertebral bodies or more than two vertebral bodies form synostosis on the front parts or the outer sides of the vertebral bodies. The present invention is matched with the bone planting fusion among the vertebral bodies to obtain better fusion among the vertebral bodies.

Description

The preceding road of a kind of vertebra biotic induce osteogenesis type inner fixing device
Technical field
The present invention relates to a kind of medical apparatus and instruments, particularly a kind of intervertebral fixation plate and relevant special equipment thereof that is used for the preceding road of spinal column belongs to medical instruments field.
Background technology
The extensive use of the operative treatment of spine disorders, wherein the intervertebral fusion technology obtains better effects because of the progress of internal fixation device, but still there are some defectives in internal fixation device, causes intervertebral fusion not reach gratifying degree.For example: the success rate of cervical intervertebral fusion at present is up to 95% in the single-unit section, can only reach 75% at multi-segmental.Existing intervertebral fusion method is the mode by preceding road fixing head and/or Invasive lumbar fusion device and/or titanium cage, makes and forms the bone connection between vertebral body, even but because the peculiar rule that bone merges can not all be grasped for people, still can not realize hundred-percent fusion rate.
Summary of the invention
The present invention solves the technological deficiency that the intervertebral fusion rate can not further improve in the prior art, provide a kind of and utilize up-to-date " spatial induction effect theory " to be the basis, rely on the induced osteogenesis effect of implant itself and realize the preceding road of the vertebra intervertebral fixation device of intervertebral fusion.
Technical scheme of the present invention is such:
The preceding road of a kind of vertebra biotic induce osteogenesis type inner fixing device comprises at least: fixing head, be arranged on the fixing hole on the fixing head; That the bottom of described fixing head also is provided with induced osteogenesis or guiding osteanagenesis is for the pre-trough for placing ribs of implanting from body or allograph bone or other artificial bones of at least one fixing head.Described artificial bone can be the nanometer bone, and the artificial bone that can make for hydroxyapatite material can also be activated cell engineering bone.
The pre-trough for placing ribs of aforesaid fixing head protrudes in the fixing head bottom, and the opening direction of pre-trough for placing ribs is downward, and its shape of cross section is rectangle or other geometry.
Aforesaid fixing head is provided with four or more fixing hole, and those holes lay respectively at the two ends of fixing head, arranges with transverse axis.Aforesaid fixing hole is angling hole or forward screwed hole or leaning thread hole or T shape hole or the trapezoidal hole that falls.
Aforesaid fixing head has and the akin vertical radian of the physiological bending angle of vertebra; Described vertical radian is the 10-15 degree, and laterally radian is 6 degree; The edge of described fixing head is further designed to circular-arc.
The present invention also can comprise an osteotome, and described osteotome cross-sectional width is identical with corresponding fixing head bottom bone groove cross-sectional width, so that pre-trough for placing ribs can embed just.
Aforesaid fixing head and staple are made by titanium alloy or other metal or nonmetallic materials.
The periphery of the pre-trough for placing ribs of aforesaid fixing head is provided with porose, and making pre-trough for placing ribs is the cage shape.
The pre-trough for placing ribs of aforesaid fixing head adds the biotic factor of promotion skeletonization such as having, and described biotic factor is BMP or other biotic factor, and described biotic factor is liquid state or graininess or is combined into membranaceous.Biotic factor can directly be sneaked in the pre-trough for placing ribs of fixing head in operation process; Also can be preset in the pre-trough for placing ribs of fixing head
The present invention compared with prior art has remarkable advantages and beneficial effect.
The present invention is owing to be provided with for the pre-trough for placing ribs of implanting from body or allograph bone or other artificial bones that protrudes in plate in the bottom of plate, when operation, in advance bone is inserted in the groove, utilize the spatial induction effect of fixing head, make and intend between fixed adjacent vertebral bodies or two above vertebral bodys in the vertebral body front portion or the outside forms synostosis, cooperate interbody bone graft to merge, can reach between better vertebral body and merge.The high fusion rate that technical solution of the present invention realizes can make patient's vertebral body disease obtain radical cure, has avoided the patient because of not merging the misery of operation once more that causes.The length of described fixing head and fixing hole what as required fixed intervertebral space what and decide, vertical radian of fixing head helps recovering normal vertebra physiological bending after making the present invention fixing, the edge of fixing head becomes the circular-arc stimulation that reduces fixing head to tissue, also can reduce materials and reduce cost.The present invention digs out the shallow slot that is complementary with pre-trough for placing ribs in advance fast on vertebral body when osteotome being set being used to perform the operation, to shorten operating time as far as possible.
Description of drawings
Fig. 1 is the structural representation of an embodiment of fixing head of the present invention;
Fig. 2 is the longitudinal sectional drawing of Fig. 1 of the present invention;
Fig. 3 is the section of structure of grooved osteotome of the present invention;
Fig. 4 is the vertical view of Fig. 3 of the present invention;
Fig. 5 is fixed in the sketch map of vertebrae for the present invention.
The specific embodiment
The present invention is described in further detail below in conjunction with accompanying drawing and specific embodiment:
See also the structural representation that Figure 1 shows that an embodiment of fixing head of the present invention, the centre position of fixing head 1 is that a cross section with fixing head 1 one is rectangular pre-trough for placing ribs 4, the pre-trough for placing ribs 4 of rectangle is for implanting from body or allograph bone or other artificial bones, the pre-trough for placing ribs 4 of rectangle protrudes in the bottom of plate, see Fig. 2, the pre-trough for placing ribs of rectangle 4 is implanted from body or allograph bone or artificial bone and with after vertebral body is connected, can be connected with user cone shape skeletonization, promptly pre-trough for placing ribs 4 has the spatial induction effect of induced osteogenesis or guiding osteanagenesis.Pre-trough for placing ribs 4 can be for protruding in the random geometry of fixing head 1, and is cylindrical as rhombus, can also the hole be set in the part that protrudes in fixing head 1, forms the pre-trough for placing ribs of cage shape.On a fixing head 1 two or more pre-trough for placing ribs 4 can be set, fixing head 1 can be across two or more cones.
Be respectively equipped with 2 oblique fixing holes 3 at the two ends of fixing head 1, those fixing holes 3 are arranged with the transverse axis of fixing head 1.Four fixing holes 3 are angling hole or forward screwed hole or leaning thread hole or T shape hole or the trapezoidal hole that falls.Steel nail is oblique to be passed steel plate by fixing hole 3 and hammers into vertebrae.
Seeing also shown in Figure 2ly, is the longitudinal sectional drawing of Fig. 1 of the present invention, as can be seen from the figure, and its top 12 curved shapes, its underpart 14,15 also curved shapes; Fixing head 1 thereby have and the akin vertical radian of the physiological bending angle of vertebra; Described vertical radian can be the 10-15 degree, and laterally radian the best is 6 degree; The edge 11 of fixing head 1 is further designed to circular-arc.
See also Fig. 3, shown in Figure 4, be the section of structure and the vertical view of osteotome of the present invention;
The four edges of described osteotome 30 bottom surfaces is a bit larger tham the four edges with the pre-trough for placing ribs 4 in fixing head bottom, so that pre-trough for placing ribs 4 can embed just; The periphery of the bottom of osteotome 30 is sharp shape, and the mid portion 31 of bottom is a hollow form, and 313 is the edge of grooved osteotome 30 hollow forms as shown in Figure 4, and the top 32 of grooved osteotome 30 is for impacting the force part of grooved osteotome downwards.311 and 312 of grooved osteotome corresponds respectively to the width and the length of pre-trough for placing ribs as shown in Figure 1 and Figure 2.
When operation, in advance bone is placed in the pre-trough for placing ribs 4, utilize the spatial induction effect of fixing head, make and intend between fixed adjacent vertebral bodies or two above vertebral bodys in the vertebral body front portion or the outside forms synostosis, cooperate interbody bone graft to merge, merge to reach between better vertebral body, for cervical vertebra, vertebral body single-unit section fusion rate is approached or reach 100%, the multi-segmental fusion rate is far above 75%.Also can reach close fusion rate for lumbar vertebra and thoracic vertebra.Ready-formed bone not only comprises from body or allograph bone, also comprises artificial bone, the artificial bone that forms as nanotechnology, the artificial bone that can also make for hydroxyapatite material, or activated tissue engineered bone.That presets can also add the biotic factor that BMP etc. promotes skeletonization from body or allograph bone or other artificial bones, biotic factor comprises that a variety of BMP are a kind of, biotic factor can be a variety of way with mixing of bone, as being dissolved in advance in the bone, also can be mixed in the bone temporarily, also can earlier biotic factor and other materials be prefabricated into particle, thin film or the like shape, or mix or be wrapped in the bone graft.
See also shown in Figure 5, be fixed in the sketch map of vertebrae for the present invention, as we can see from the figure, fixing head 1 be fixed in the anterior longitudinal ligaments of two vertebral bodys 20 and vertebral body the first five/position, preset bone in the pre-trough for placing ribs 4 of fixing head 1 bottom, combine with the part of vertebral body 20, staple 22 is by fixing head 1 outer penetrating, be fixed in the vertebral body 20,21 are equipped with in being and preset bone and connect the titanium cage of going up hypocentrum 20.
Aforementioned fixation plate 1 and staple 22 are made by titanium alloy or steel plate; Used steel plate has 33 kinds of specifications, presses the length branch: the 20-90mm steel plate, and whenever increasing progressively 2.5mm is a kind of specification; The 90-110mm steel plate, whenever increasing progressively 5mm is a kind of specification.All steel plate widths are 15mm, and steel plate thickness is 1.6-2.5mm, and steel plate screw fixing hole diameter is 3.5mm or 4.5mm, and screw length is 11-15mm, and screw diameter is 3.5mm or 4.5mm.
The present invention still needs and cooperates interbody bone graft to merge, to strive for reaching hundred-percent fusion rate.The length of described plate and hole what as required fixed intervertebral space what and decide.Vertical radian of fixing head helps recovering normal vertebra physiological bending after making the present invention fixing.The edge of fixing head becomes the circular-arc stimulation that reduces fixing head to tissue, also can reduce materials and reduce cost.
It should be noted that at last: above embodiment only in order to the explanation the present invention and and unrestricted technical scheme described in the invention; Therefore, although this description has been described in detail the present invention with reference to each above-mentioned embodiment,, those of ordinary skill in the art should be appreciated that still and can make amendment or be equal to replacement the present invention; And all do not break away from the technical scheme and the improvement thereof of the spirit and scope of the present invention, and it all should be encompassed in the middle of the claim scope of the present invention.

Claims (10)

1, the preceding road of a kind of vertebra biotic induce osteogenesis type inner fixing device comprises at least: fixing head, be arranged on the fixing hole on the fixing head; It is characterized in that: the bottom of described fixing head also is provided with at least one fixing head pre-trough for placing ribs of the confession implantation of induced osteogenesis or guiding osteanagenesis from body or allograph bone or other artificial bones, the pre-trough for placing ribs of described fixing head protrudes in the fixing head bottom, and the opening direction of pre-trough for placing ribs is downward.
2, the preceding road of a kind of vertebra according to claim 1 biotic induce osteogenesis type inner fixing device is characterized in that: described pre-trough for placing ribs shape of cross section is a rectangle.
3, the preceding road of a kind of vertebra according to claim 1 and 2 biotic induce osteogenesis type inner fixing device, it is characterized in that: described fixing head is provided with four or more fixing hole, and those holes lay respectively at the two ends of fixing head, arrange with transverse axis.
4, the preceding road of a kind of vertebra according to claim 3 biotic induce osteogenesis type inner fixing device is characterized in that: described fixing hole is angling hole or forward screwed hole or leaning thread hole or T shape hole or the trapezoidal hole that falls.
5, the preceding road of a kind of vertebra according to claim 1 and 2 biotic induce osteogenesis type inner fixing device is characterized in that: described fixing head has and the akin vertical radian of the physiological bending angle of vertebra; Described vertical radian is the 10-15 degree, and laterally radian is 6 degree; The edge of described fixing head is further designed to circular-arc.
6, the preceding road of a kind of vertebra according to claim 1 and 2 biotic induce osteogenesis type inner fixing device, it is characterized in that: also comprise an osteotome, described osteotome cross-sectional width is identical with the pre-trough for placing ribs cross-sectional width in corresponding fixing head bottom, so that pre-trough for placing ribs can embed just.
7, the preceding road of a kind of vertebra according to claim 1 and 2 biotic induce osteogenesis type inner fixing device, it is characterized in that: described fixing head is made by titanium alloy or steel.
8, the preceding road of a kind of vertebra according to claim 1 and 2 biotic induce osteogenesis type inner fixing device is characterized in that: the peripherally disposed apertures of the pre-trough for placing ribs of described fixing head, making pre-trough for placing ribs is the cage shape.
9, the preceding road of a kind of vertebra according to claim 1 and 2 biotic induce osteogenesis type inner fixing device is characterized in that: described pre-trough for placing ribs adds the biotic factor that promotes skeletonization.
10, the preceding road of a kind of vertebra according to claim 9 biotic induce osteogenesis type inner fixing device is characterized in that described biotic factor is a bone morphogenetic protein, and described biotic factor is liquid state or graininess or is combined into membranaceous.
CNB2004100034273A 2004-03-01 2004-03-01 Vetebrae anterior biological osteogenesis-inducing type internal fixing device Expired - Fee Related CN100344266C (en)

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100553578C (en) * 2008-03-31 2009-10-28 中国人民解放军第三军医大学第二附属医院 Waist 5 vertebras of spinal column and the preceding road of sacrum 1 vertebra internal fixation steel plate
CN101716095B (en) * 2009-12-30 2012-07-11 中国科学院长春应用化学研究所 Orthopedic internal fixation plate and preparation method thereof
CN102048601B (en) * 2010-12-29 2013-04-17 哈尔滨医科大学 Piston type titanium wire mesh cage and manufacturing method thereof
CN103536346A (en) * 2013-10-18 2014-01-29 江苏艾迪尔医疗科技股份有限公司 Manufacturing method of orthopaedic fixing device
CN110025410A (en) * 2019-05-10 2019-07-19 云南欧铂斯医疗科技有限公司 Fixed device is merged in embedded anterior cervical vertebrae pressurization

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066175A (en) * 1993-02-16 2000-05-23 Henderson; Fraser C. Fusion stabilization chamber
US6235059B1 (en) * 1996-04-03 2001-05-22 Scient'x (Societe A Responsabilite Limitee) Intersomatic setting and fusion system
CN1372869A (en) * 2002-04-09 2002-10-09 中国人民解放军第二军医大学 Equipment for fusing steel sheet before neck

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066175A (en) * 1993-02-16 2000-05-23 Henderson; Fraser C. Fusion stabilization chamber
US6235059B1 (en) * 1996-04-03 2001-05-22 Scient'x (Societe A Responsabilite Limitee) Intersomatic setting and fusion system
CN1372869A (en) * 2002-04-09 2002-10-09 中国人民解放军第二军医大学 Equipment for fusing steel sheet before neck

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Assignee: Nayao Medical Technology Co., Ltd., Beijing

Assignor: Wang Yan

Contract fulfillment period: 2007.10.31 to 2017.10.30 contract change

Contract record no.: 2008110000143

Denomination of invention: Vetebrae anterior biological osteogenesis-inducing type internal fixing device

Granted publication date: 20071024

License type: Exclusive license

Record date: 2008.12.1

LIC Patent licence contract for exploitation submitted for record

Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2007.10.31 TO 2017.10.30; CHANGE OF CONTRACT

Name of requester: BEIJING NATONG MEDICAL TREATMENT TECHNOLOGY CO., L

Effective date: 20081201

C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20071024

Termination date: 20120301