CL2022001937A1 - Anti-pmel17 antibodies and conjugates thereof (divisional 202101607) - Google Patents

Anti-pmel17 antibodies and conjugates thereof (divisional 202101607)

Info

Publication number
CL2022001937A1
CL2022001937A1 CL2022001937A CL2022001937A CL2022001937A1 CL 2022001937 A1 CL2022001937 A1 CL 2022001937A1 CL 2022001937 A CL2022001937 A CL 2022001937A CL 2022001937 A CL2022001937 A CL 2022001937A CL 2022001937 A1 CL2022001937 A1 CL 2022001937A1
Authority
CL
Chile
Prior art keywords
antibodies
antigen
binding fragments
antibody
methods
Prior art date
Application number
CL2022001937A
Other languages
Spanish (es)
Inventor
Burger Matthew
Anthony D'ALESSIO Joseph
Fleming Tony
Rauniyar Vivek
Manchado ROBLES Eusebio
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to CL2022001937A priority Critical patent/CL2022001937A1/en
Publication of CL2022001937A1 publication Critical patent/CL2022001937A1/en

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente solicitud describe anticuerpos anti-PMEL17, fragmentos de unión a antígeno de los mismos, y conjugados de anticuerpo fármaco de dichos anticuerpos o fragmentos de unión a antígeno conjugados a un inhibidor de GNAQ/GNA11. La invención además se refiere a métodos para tratar o prevenir el cáncer usando los anticuerpos, fragmentos de unión a antígeno, y conjugados de anticuerpo fármaco. Además se describen métodos de preparación de anticuerpos, fragmentos de unión a antígeno, y conjugados de anticuerpo fármaco, y métodos de uso de los anticuerpos y fragmentos de unión a antígeno como reactivos de diagnóstico.The present application describes anti-PMEL17 antibodies, antigen-binding fragments thereof, and antibody-drug conjugates of such antibodies or antigen-binding fragments conjugated to a GNAQ/GNA11 inhibitor. The invention further relates to methods of treating or preventing cancer using the antibodies, antigen-binding fragments, and antibody-drug conjugates. Further described are methods of preparing antibodies, antigen-binding fragments, and antibody-drug conjugates, and methods of using the antibodies and antigen-binding fragments as diagnostic reagents.

CL2022001937A 2022-07-18 2022-07-18 Anti-pmel17 antibodies and conjugates thereof (divisional 202101607) CL2022001937A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CL2022001937A CL2022001937A1 (en) 2022-07-18 2022-07-18 Anti-pmel17 antibodies and conjugates thereof (divisional 202101607)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2022001937A CL2022001937A1 (en) 2022-07-18 2022-07-18 Anti-pmel17 antibodies and conjugates thereof (divisional 202101607)

Publications (1)

Publication Number Publication Date
CL2022001937A1 true CL2022001937A1 (en) 2023-04-10

Family

ID=86337435

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2022001937A CL2022001937A1 (en) 2022-07-18 2022-07-18 Anti-pmel17 antibodies and conjugates thereof (divisional 202101607)

Country Status (1)

Country Link
CL (1) CL2022001937A1 (en)

Similar Documents

Publication Publication Date Title
CL2021001607A1 (en) Anti-pmel17 antibodies and conjugates thereof
CY1121254T1 (en) ANTI-CTLA-4 ANTIBODIES COMPOSITIONS
BR112021023229A2 (en) mcl-1 inhibitor antibody-drug conjugates and methods of use
ES2328474T3 (en) ISCOM PREPARATION AND ITS USE.
BR112021008060A2 (en) Polypeptide, anti-ctla4 antibody or antibody fragment, immunoconjugate, pharmaceutical composition, single dose of pharmaceutical composition, method of treating cancer, and, kit for diagnosis or treatment
CO2022003582A2 (en) Methods for the treatment of thyroid ophthalmopathy
BR112022024833A2 (en) ANTI-BCMA-DRUG ANTIBODY CONJUGATES AND METHODS OF USE
CO2023002375A2 (en) Antibodies against ilt2 and use thereof
CO2022002573A2 (en) Antibodies against ilt2 and their use
BR112021016596A2 (en) Anti-pd-l1 antibody and its use
PE20231104A1 (en) BRM ANTIBODY CONJUGATED CHEMICAL DEGRADATION INDUCERS AND METHODS THEREOF
ECSP23073625A (en) ANTI-NECTIN-4 ANTIBODY AND EXATECANE CONJUGATES
CO2023004110A2 (en) Anti-fgfr2 antibodies and methods of using them
CL2022001937A1 (en) Anti-pmel17 antibodies and conjugates thereof (divisional 202101607)
CO2021017477A2 (en) combination therapy
CO2023016712A2 (en) Neodegrader-anti-cd33 antibody conjugates
BR112023000455A2 (en) TREATMENT OF INFLAMMATORY DISEASE USING ANTI-TISSUE FACTOR ANTIBODIES
BR112023021475A2 (en) ANTIBODY-DRUG CONJUGATES AND METHODS FOR PRODUCING THEM
BR112022009672A2 (en) TREATMENT OF CANCER WITH ANTIBODY-DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS
CL2023000084A1 (en) Anti-betacellulin antibodies, fragments thereof, and multispecific binding molecules
BR112022024361A2 (en) TUBULISINS AND PROTEIN-TUBULISIN CONJUGATES
AR122660A2 (en) ANTI-PMEL17 ANTIBODIES AND CONJUGATES THEREOF
BR112022024691A2 (en) BISPECIFIC ANTIBODY CONJUGATES - DRUG TARGETED TO EGFR AND MUC1 AND THEIR USES
CO2021016982A2 (en) Methods of using a bispecific antigen-binding construct targeting her2 for the treatment of bile duct cancers
BR112022020716A2 (en) ANTI-TUMOR ANTIBODIES ASSOCIATED WITH ANTIGEN AND THEIR USES