CL2022001806A1 - Method for producing diphenylmethane derivative. - Google Patents
Method for producing diphenylmethane derivative.Info
- Publication number
- CL2022001806A1 CL2022001806A1 CL2022001806A CL2022001806A CL2022001806A1 CL 2022001806 A1 CL2022001806 A1 CL 2022001806A1 CL 2022001806 A CL2022001806 A CL 2022001806A CL 2022001806 A CL2022001806 A CL 2022001806A CL 2022001806 A1 CL2022001806 A1 CL 2022001806A1
- Authority
- CL
- Chile
- Prior art keywords
- diphenylmethane derivative
- producing
- synthesis route
- synthesis
- linear
- Prior art date
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- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
La presente invención se refiere a un método mejorado para producir un derivado de difenilmetano que es eficaz como inhibidor del cotransportador de glucosa dependiente de sodio (SGLT), el método se lleva a cabo por medio de un método de síntesis convergente en el cual cada grupo principal se sintetiza por separado y luego se acopla. Como tal, en comparación con un método de síntesis lineal descrito en documentos existentes, la ruta de síntesis es compacta y el rendimiento puede aumentarse, y los factores de riesgo inherentes a la ruta de síntesis lineal pueden reducirse. Además, la forma cristalina del compuesto producido de acuerdo con el método tiene excelentes características fisicoquímicas y, por lo tanto, puede utilizarse de manera efectiva en campos como la fabricación farmacéutica.The present invention refers to an improved method for producing a diphenylmethane derivative that is effective as an inhibitor of the sodium-dependent glucose cotransporter (SGLT), the method is carried out by means of a convergent synthesis method in which each group main is synthesized separately and then coupled. As such, compared to a linear synthesis method described in existing papers, the synthesis route is compact and the yield can be increased, and the risk factors inherent in the linear synthesis route can be reduced. Furthermore, the crystalline form of the compound produced according to the method has excellent physicochemical characteristics and therefore can be effectively used in fields such as pharmaceutical manufacturing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2022001806A CL2022001806A1 (en) | 2022-07-01 | 2022-07-01 | Method for producing diphenylmethane derivative. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2022001806A CL2022001806A1 (en) | 2022-07-01 | 2022-07-01 | Method for producing diphenylmethane derivative. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2022001806A1 true CL2022001806A1 (en) | 2023-04-14 |
Family
ID=86337436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2022001806A CL2022001806A1 (en) | 2022-07-01 | 2022-07-01 | Method for producing diphenylmethane derivative. |
Country Status (1)
| Country | Link |
|---|---|
| CL (1) | CL2022001806A1 (en) |
-
2022
- 2022-07-01 CL CL2022001806A patent/CL2022001806A1/en unknown
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